sumatriptan has been researched along with Depression in 8 studies
Sumatriptan: A serotonin agonist that acts selectively at 5HT1 receptors. It is used in the treatment of MIGRAINE DISORDERS.
sumatriptan : A sulfonamide that consists of N,N-dimethyltryptamine bearing an additional (N-methylsulfamoyl)methyl substituent at position 5. Selective agonist for a vascular 5-HT1 receptor subtype (probably a member of the 5-HT1D family). Used (in the form of its succinate salt) for the acute treatment of migraine with or without aura in adults.
Depression: Depressive states usually of moderate intensity in contrast with MAJOR DEPRESSIVE DISORDER present in neurotic and psychotic disorders.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In order to investigate the plausible association of migraine recurrence with anxiety and depressive symptoms, a multicentre, randomized, double-blind, placebo-controlled, crossover clinical trial was conducted using sumatriptan as a vehicle drug." | 5.14 | Migraine recurrence is not associated with depressive or anxiety symptoms. Results of a randomized controlled trial. ( Charmoussi, S; Doitsini, S; Georgiadis, G; Kodounis, A; Mitsikostas, DD; Thomas, A; Vikelis, M; Xifaras, M; Zaglis, D, 2010) |
| "1997, sumatriptan-treated migraineurs had significantly higher depression PCRs (22." | 3.70 | Are triptans with enhanced lipophilicity used for the acute treatment of migraine associated with an increased consulting rate for depressive illness? ( Croft, P; Frischer, M; Goadsby, PJ; Millson, D, 2000) |
| "The prevalence of migraine is 8% in men and 12-15% in women." | 2.44 | [Current diagnosis and treatment of migraine]. ( Diener, HC; Katsarava, Z; Limmroth, V, 2008) |
| "Major depression and migraine are commonly comorbid." | 1.30 | Co-administration of fluoxetine and sumatriptan: the Canadian experience. ( Joffe, RT; Sokolov, ST, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (50.00) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mitsikostas, DD | 1 |
| Vikelis, M | 1 |
| Kodounis, A | 1 |
| Zaglis, D | 1 |
| Xifaras, M | 1 |
| Doitsini, S | 1 |
| Georgiadis, G | 1 |
| Thomas, A | 1 |
| Charmoussi, S | 1 |
| Lee, LY | 1 |
| Abbott, L | 1 |
| Mahlangu, B | 1 |
| Moodie, SJ | 1 |
| Anderson, S | 1 |
| Diener, HC | 1 |
| Katsarava, Z | 1 |
| Limmroth, V | 1 |
| Leung, M | 1 |
| Ong, M | 1 |
| Meyer, C | 1 |
| Joffe, RT | 1 |
| Sokolov, ST | 1 |
| Putnam, GP | 1 |
| O'Quinn, S | 1 |
| Bolden-Watson, CP | 1 |
| Davis, RL | 1 |
| Gutterman, DL | 1 |
| Fox, AW | 1 |
| Millson, D | 1 |
| Frischer, M | 1 |
| Croft, P | 1 |
| Goadsby, PJ | 1 |
2 reviews available for sumatriptan and Depression
| Article | Year |
|---|---|
The management of cyclic vomiting syndrome: a systematic review.
Topics: Adrenergic beta-Antagonists; Age of Onset; Antidepressive Agents, Tricyclic; Depression; Female; Hea | 2012 |
[Current diagnosis and treatment of migraine].
Topics: Acupuncture Therapy; Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Analgesics; Behavior Ther | 2008 |
1 trial available for sumatriptan and Depression
| Article | Year |
|---|---|
Migraine recurrence is not associated with depressive or anxiety symptoms. Results of a randomized controlled trial.
Topics: Adult; Anxiety; Cross-Over Studies; Depression; Double-Blind Method; Female; Humans; Male; Middle Ag | 2010 |
5 other studies available for sumatriptan and Depression
| Article | Year |
|---|---|
Lack of an interaction between sumatriptan and selective serotonin reuptake inhibitors.
Topics: Adult; Antidepressive Agents, Second-Generation; Depression; Drug Interactions; Female; Humans; Male | 1995 |
New drugs. In the realm of the brain.
Topics: Central Nervous System Agents; Depression; Humans; Hypnotics and Sedatives; Migraine Disorders; Paro | 1993 |
Co-administration of fluoxetine and sumatriptan: the Canadian experience.
Topics: Canada; Depression; Drug Interactions; Drug Therapy, Combination; Fluoxetine; Humans; Migraine Disor | 1997 |
Migraine polypharmacy and the tolerability of sumatriptan: a large-scale, prospective study.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Anti-As | 1999 |
Are triptans with enhanced lipophilicity used for the acute treatment of migraine associated with an increased consulting rate for depressive illness?
Topics: Cohort Studies; Depression; Female; Humans; Indoles; Male; Migraine Disorders; Oxazolidinones; Piper | 2000 |