Page last updated: 2024-08-17

tetrabenazine and Depression

tetrabenazine has been researched along with Depression in 37 studies

Research

Studies (37)

TimeframeStudies, this research(%)All Research%
pre-199015 (40.54)18.7374
1990's0 (0.00)18.2507
2000's3 (8.11)29.6817
2010's16 (43.24)24.3611
2020's3 (8.11)2.80

Authors

AuthorsStudies
Depoortere, R; Jastrzębska-Więsek, M; Kołaczkowski, M; Newman-Tancredi, A; Varney, MA; Wesołowska, A1
Gürağaç Dereli, FT; Ilhan, M; Küpeli Akkol, E2
Asar, S; Correa, M; Murray, F; Presby, RE; Rotolo, RA; Salamone, JD; Tracy, O; Yang, JH1
Bogner, RH; Collins, S; Correa, M; Gorka, D; Manchanda, A; Mistry, A; Qian, E; Salamone, JD; Yohn, SE1
Abler, V; Claassen, DO; DiBonaventura, M; Gandhi, SK; Iyer, RG; Shah-Manek, B; Sung, VW1
Chabal, CC; Kamholz, JA; Killoran, A; Moser, DJ; Nopoulos, PC; Schultz, JL1
Aziz, NA1
Schultz, JL1
Macleod, M; Munafò, M; Sampaio, C; Wagenmakers, EJ; Ware, JJ1
Kamholz, JA; Killoran, A; Moser, DJ; Nopoulos, PC; Schultz, JL1
Shahani, L1
Baqi, Y; Correa, M; Freeland, C; Hart, EE; López-Cruz, L; Müller, CE; Nunes, EJ; Randall, PA; Salamone, JD; Yohn, SE1
Agarwal, PA; Appel-Cresswell, S; Dinelle, K; Farrer, MJ; Felicio, AC; Heffernan, N; McKenzie, J; Road, JD; Schulzer, M; Sossi, V; Stoessl, AJ; Wszolek, ZK1
Baqi, Y; Correa, M; Khan, B; Lee, CA; Makriyannis, A; Müller, CE; Nowak, V; Nunes, EJ; Pandit, S; Randall, PA; Salamone, JD; Shah, P; Vemuri, VK; Yohn, SE1
Anderson, KE; Beck, CA; Biglan, KM; Brocht, AF; Darwin, KC; Dorsey, ER; Nichols, PE; Shoulson, I; Singh, S1
Margolis, RL1
Guay, DR1
Franch, O; Kurtis, MM1
Rehavi, M; Schwartz, K; Weizman, A; Yadid, G1
POELDINGER, W1
ADLER, MW1
Bonelli, RM; Hofmann, P1
Battegay, R; Kahr, H; Pöldinger, W1
Nagayama, H; Tachiki, KH; Takahashi, R; Tateishi, T; Yoshida, H1
Glotzbach, RK; Irwin, GH; Kent, TA; Preskorn, SH; Solnick, JV1
Kido, A; Nagayama, H; Nakamura, E; Nishiwaki, K; Tachiki, KH; Takagi, A; Takahashi, R; Tateishi, T1
Baizman, ER; Ezrin, AM; Ferrari, RA; Luttinger, D1
Soutar, CA1
Heathfield, KW; Roberts, AH; Swash, M; Zakko, H1
McLellan, DL1
Kido, A; Morita, T; Nagayama, H; Takahashi, R1
Durell, J; Kopin, IJ; Schanberg, SM; Schildkraut, JJ1
Harmon, JB; Lynes, TE; Marvel, JP; Smith, DH; Stump, JM; Vernier, VG1
Avrutskii, GIa; Mashkovskii, MD; Polezhaeva, AI; Smulevich, AB; Vertozgadova, OP1
Benesová, O; Náhunek, K1

Reviews

3 review(s) available for tetrabenazine and Depression

ArticleYear
Tetrabenazine (Xenazine) for Huntington's chorea.
    The Medical letter on drugs and therapeutics, 2009, Jan-26, Volume: 51, Issue:1304

    Topics: Animals; Controlled Clinical Trials as Topic; Depression; Humans; Huntington Disease; Tetrabenazine; Vesicular Monoamine Transport Proteins

2009
Tetrabenazine, a monoamine-depleting drug used in the treatment of hyperkinetic movement disorders.
    The American journal of geriatric pharmacotherapy, 2010, Volume: 8, Issue:4

    Topics: Adrenergic Uptake Inhibitors; Adult; Aged; Aged, 80 and over; Clinical Trials as Topic; Cytochrome P-450 CYP2D6; Depression; Dopamine; Drug Interactions; Genotype; Humans; Huntington Disease; Hyperkinesis; Middle Aged; Movement Disorders; Neuroleptic Malignant Syndrome; Parkinson Disease, Secondary; Quinolizines; Reserpine; Serotonin; Tetrabenazine; Vesicular Monoamine Transport Proteins; Young Adult

2010
A systematic review of the treatment studies in Huntington's disease since 1990.
    Expert opinion on pharmacotherapy, 2007, Volume: 8, Issue:2

    Topics: Amantadine; Antipsychotic Agents; Chorea; Depression; Humans; Huntington Disease; Neuroprotective Agents; Riluzole; Sexual Dysfunctions, Psychological; Tetrabenazine

2007

Trials

2 trial(s) available for tetrabenazine and Depression

ArticleYear
Affective disorders and norepinephrine pharmacology.
    International psychiatry clinics, 1969, Volume: 6, Issue:2

    Topics: Animals; Behavior; Behavior, Animal; Body Temperature; Brain; Brain Chemistry; Chlorpromazine; Clinical Trials as Topic; Cocaine; Depression; Emotions; Female; Humans; Hypothermia, Induced; Imipramine; Lithium; Male; Methyltyrosines; Middle Aged; Monoamine Oxidase Inhibitors; Norepinephrine; Normetanephrine; Placebos; Rats; Reserpine; Tetrabenazine; Vanilmandelic Acid

1969
Correlation between the experimental data from animal studies and therapetical effects of antidepressant drugs.
    Psychopharmacologia, 1971, Volume: 20, Issue:4

    Topics: Animals; Antidepressive Agents; Depression; Electroencephalography; Female; Humans; Male; Nicotine; Norepinephrine; Physostigmine; Placebos; Rabbits; Reserpine; Tetrabenazine; Tremorine

1971

Other Studies

32 other study(ies) available for tetrabenazine and Depression

ArticleYear
The selective 5-HT 1A receptor agonist, NLX-112, overcomes tetrabenazine-induced catalepsy and depression-like behavior in the rat.
    Behavioural pharmacology, 2022, 08-01, Volume: 33, Issue:5

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antidepressive Agents; Buspirone; Catalepsy; Depression; Huntington Disease; Parkinsonian Disorders; Piperidines; Pyridines; Rats; Receptor, Serotonin, 5-HT1A; Serotonin; Serotonin 5-HT1 Receptor Agonists; Serotonin Receptor Agonists; Tetrabenazine

2022
Identification of the main active antidepressant constituents in a traditional Turkish medicinal plant, Centaurea kurdica Reichardt.
    Journal of ethnopharmacology, 2020, Mar-01, Volume: 249

    Topics: Animals; Antidepressive Agents; Centaurea; Depression; Flowers; Hindlimb Suspension; Male; Medicine, Traditional; Methanol; Mice; Mice, Inbred BALB C; Phytotherapy; Plant Components, Aerial; Plant Extracts; Plant Leaves; Plants, Medicinal; Quercetin; Tetrabenazine

2020
The novel atypical dopamine transport inhibitor CT-005404 has pro-motivational effects in neurochemical and inflammatory models of effort-based dysfunctions related to psychopathology.
    Neuropharmacology, 2021, 02-01, Volume: 183

    Topics: Animals; Choice Behavior; Conditioning, Operant; Depression; Dopamine Plasma Membrane Transport Proteins; Feeding Behavior; Interleukin-1beta; Male; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Reward; Tetrabenazine; Vesicular Monoamine Transport Proteins

2021
Oral Ingestion and Intraventricular Injection of Curcumin Attenuates the Effort-Related Effects of the VMAT-2 Inhibitor Tetrabenazine: Implications for Motivational Symptoms of Depression.
    Journal of natural products, 2017, 10-27, Volume: 80, Issue:10

    Topics: Administration, Oral; Animals; Choice Behavior; Curcuma; Curcumin; Depression; Feeding Behavior; Injections, Intraventricular; Male; Molecular Structure; Motivation; Rats; Rats, Sprague-Dawley; Tetrabenazine; Vesicular Monoamine Transport Proteins

2017
Physician perceptions of pharmacologic treatment options for chorea associated with Huntington disease in the United States.
    Current medical research and opinion, 2018, Volume: 34, Issue:4

    Topics: Activities of Daily Living; Adult; Aged; Chorea; Cross-Sectional Studies; Depression; Female; Humans; Huntington Disease; Male; Middle Aged; Perception; Physicians; Quality of Life; Surveys and Questionnaires; Tetrabenazine; United States

2018
Evaluating depression and suicidality in tetrabenazine users with Huntington disease.
    Neurology, 2018, 07-17, Volume: 91, Issue:3

    Topics: Adrenergic Uptake Inhibitors; Adult; Aged; Depression; Female; Humans; Huntington Disease; Longitudinal Studies; Male; Middle Aged; Suicidal Ideation; Tetrabenazine; Vesicular Monoamine Transport Proteins

2018
Discovery of new antidepressant agents: In vivo study on Anthemis wiedemanniana Fisch. & Mey.
    Journal of ethnopharmacology, 2018, Nov-15, Volume: 226

    Topics: Adrenergic Uptake Inhibitors; Animals; Anthemis; Antidepressive Agents; Behavior, Animal; Depression; Female; Flowers; Hindlimb Suspension; Hypothermia; Locomotion; Male; Mice, Inbred BALB C; Plant Extracts; Tetrabenazine

2018
Reader response: Evaluating depression and suicidality in tetrabenazine users with Huntington disease.
    Neurology, 2019, 02-26, Volume: 92, Issue:9

    Topics: Depression; Depressive Disorder; Humans; Huntington Disease; Suicide; Tetrabenazine

2019
Author response: Evaluating depression and suicidality in tetrabenazine users with Huntington disease.
    Neurology, 2019, 02-26, Volume: 92, Issue:9

    Topics: Depression; Depressive Disorder; Humans; Huntington Disease; Suicide; Tetrabenazine

2019
Reader response: Evaluating depression and suicidality in tetrabenazine users with Huntington disease.
    Neurology, 2019, 02-26, Volume: 92, Issue:9

    Topics: Depression; Depressive Disorder; Humans; Huntington Disease; Suicide; Tetrabenazine

2019
Author response: Evaluating depression and suicidality in tetrabenazine users with Huntington disease.
    Neurology, 2019, 02-26, Volume: 92, Issue:9

    Topics: Depression; Depressive Disorder; Humans; Huntington Disease; Suicide; Tetrabenazine

2019
Tetrabenazine and suicidal ideation.
    The Journal of neuropsychiatry and clinical neurosciences, 2013,Winter, Volume: 25, Issue:1

    Topics: Adrenergic Uptake Inhibitors; Depression; Female; Humans; Huntington Disease; Middle Aged; Suicidal Ideation; Tetrabenazine

2013
Effort-related motivational effects of the VMAT-2 inhibitor tetrabenazine: implications for animal models of the motivational symptoms of depression.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2013, Dec-04, Volume: 33, Issue:49

    Topics: Adenosine A2 Receptor Antagonists; Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents, Second-Generation; Behavior, Animal; Bupropion; Conditioning, Operant; Depression; Disease Models, Animal; Dopamine; Dopamine and cAMP-Regulated Phosphoprotein 32; Enkephalins; Feeding Behavior; Immunohistochemistry; Male; Microdialysis; Motivation; Nucleus Accumbens; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Substance P; Tetrabenazine; Vesicular Monoamine Transport Proteins; Xanthines

2013
In vivo dopaminergic and serotonergic dysfunction in DCTN1 gene mutation carriers.
    Movement disorders : official journal of the Movement Disorder Society, 2014, Volume: 29, Issue:9

    Topics: Adult; Aniline Compounds; Corpus Striatum; Depression; Dopamine; Dynactin Complex; Fluorine Radioisotopes; Humans; Hypoventilation; Microtubule-Associated Proteins; Middle Aged; Mutation; Parkinsonian Disorders; Positron-Emission Tomography; Raclopride; Serotonin; Sulfides; Tetrabenazine; Tomography, Emission-Computed

2014
The VMAT-2 inhibitor tetrabenazine affects effort-related decision making in a progressive ratio/chow feeding choice task: reversal with antidepressant drugs.
    PloS one, 2014, Volume: 9, Issue:6

    Topics: Animals; Antidepressive Agents; Benzazepines; Benzophenones; Bupropion; Cannabinoid Receptor Antagonists; Choice Behavior; Depression; Dopamine Antagonists; Drug Evaluation, Preclinical; Feeding Behavior; Male; Nitrophenols; Pyrazoles; Rats, Sprague-Dawley; Salicylamides; Selegiline; Tetrabenazine; Tolcapone; Vesicular Monoamine Transport Proteins; Xanthines

2014
Depressed mood and suicidality in individuals exposed to tetrabenazine in a large Huntington disease observational study.
    Journal of Huntington's disease, 2013, Volume: 2, Issue:4

    Topics: Adrenergic Uptake Inhibitors; Adult; Depression; Female; Humans; Huntington Disease; Male; Middle Aged; Suicidal Ideation; Tetrabenazine

2013
Tetrabenazine, depression and suicide: good news.
    Journal of Huntington's disease, 2014, Volume: 3, Issue:2

    Topics: Adrenergic Uptake Inhibitors; Depression; Humans; Huntington Disease; Suicide; Tetrabenazine

2014
Tardive syndrome and Parkinson's disease responsive to concomitant tetrabenazine and levodopa therapy.
    Parkinsonism & related disorders, 2011, Volume: 17, Issue:10

    Topics: Aged; Antiparkinson Agents; Antipsychotic Agents; Depression; Female; Flupenthixol; Humans; Levodopa; Movement Disorders; Parkinson Disease; Tetrabenazine

2011
Decreased limbic vesicular monoamine transporter 2 in a genetic rat model of depression.
    Brain research, 2003, Mar-07, Volume: 965, Issue:1-2

    Topics: Animals; Depression; Disease Models, Animal; Limbic System; Male; Membrane Glycoproteins; Membrane Transport Proteins; Neuropeptides; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tetrabenazine; Vesicular Biogenic Amine Transport Proteins; Vesicular Monoamine Transport Proteins

2003
COMBINED ADMINISTRATION OF DESIPRAMINE AND RESERPINE OR TETRABENAZINE IN DEPRESSIVE PATIENTS.
    Psychopharmacologia, 1963, May-21, Volume: 4

    Topics: Antidepressive Agents; Depression; Depressive Disorder; Desipramine; Humans; Imipramine; Reserpine; Tetrabenazine

1963
ENHANCED DEPRESSANT EFFECT OF TETRABENAZINE AFTER REPEATED ADMINISTRATION.
    Psychopharmacologia, 1964, Apr-03, Volume: 5

    Topics: Depression; Depressive Disorder; Movement; Pharmacology; Rats; Research; Tetrabenazine

1964
[Psychopathological complications in antidepressant medication].
    Arzneimittel-Forschung, 1966, Volume: 16, Issue:2

    Topics: Amitriptyline; Animals; Antidepressive Agents; Blood Pressure; Delirium; Depression; Desipramine; Dogs; Guinea Pigs; Humans; Imipramine; Mice; Movement; Rats; Tetrabenazine

1966
Serotonin metabolism of animal model of depression.
    Advances in experimental medicine and biology, 1981, Volume: 133

    Topics: Animals; Behavior, Animal; Brain; Conditioning, Psychological; Depression; Disease Models, Animal; Dopamine; Humans; Hydroxyindoleacetic Acid; Male; Motor Activity; Movement; Norepinephrine; Rats; Serotonin; Tetrabenazine

1981
Cerebromicrocirculatory defects in animal model of depression.
    Psychopharmacology, 1984, Volume: 84, Issue:2

    Topics: Amitriptyline; Animals; Brain; Carbon Dioxide; Cerebrovascular Circulation; Depression; Disease Models, Animal; Dopamine; Humans; Male; Microcirculation; Norepinephrine; Rats; Rats, Inbred Strains; Tetrabenazine

1984
Animal model of depression. III. Mechanism of action of tetrabenazine.
    Biological psychiatry, 1978, Volume: 13, Issue:4

    Topics: 5-Hydroxytryptophan; Animals; Brain; Brain Chemistry; Depression; Disease Models, Animal; Dopamine; Drug Synergism; Fenclonine; Humans; Hydroxyindoleacetic Acid; Male; Motor Activity; Norepinephrine; Rats; Serotonin; Serotonin Antagonists; Tetrabenazine

1978
Pharmacologic profile of fezolamine fumarate: a nontricyclic antidepressant in animal models.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 243, Issue:1

    Topics: Animals; Antidepressive Agents; Biological Transport; Blepharoptosis; Brain; Depression; Disease Models, Animal; Dogs; Dopamine; Imipramine; Mice; Monoamine Oxidase Inhibitors; Motor Activity; Norepinephrine; Purkinje Cells; Pyrazoles; Rats; Reserpine; Serotonin; Synaptosomes; Tetrabenazine

1987
Tetrabenazine for Huntington's chorea.
    British medical journal, 1970, Oct-03, Volume: 4, Issue:5726

    Topics: Depression; Humans; Huntington Disease; Male; Middle Aged; Tetrabenazine

1970
Treatment of involuntary movement disorders with tetrabenazine.
    Journal of neurology, neurosurgery, and psychiatry, 1972, Volume: 35, Issue:2

    Topics: Adolescent; Adult; Aged; Amantadine; Child; Depression; Dystonia Musculorum Deformans; Evaluation Studies as Topic; Female; Humans; Huntington Disease; Male; Middle Aged; Movement Disorders; Sleep Initiation and Maintenance Disorders; Tetrabenazine; Torticollis

1972
The suppression of involuntary movements with tetrabenazine.
    Scottish medical journal, 1972, Volume: 17, Issue:11

    Topics: Adolescent; Adult; Aged; Ataxia; Athetosis; Depression; Diencephalon; Evaluation Studies as Topic; Female; Humans; Huntington Disease; Male; Middle Aged; Movement Disorders; Nausea; Parkinson Disease; Tetrabenazine; Time Factors; Tremor

1972
An animal model of depression.
    Biological psychiatry, 1974, Volume: 9, Issue:2

    Topics: Acoustic Stimulation; Animals; Behavior, Animal; Conditioning, Classical; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Humans; Imipramine; Injections, Intraperitoneal; Male; Motor Activity; Rats; Tetrabenazine

1974
The toxicologic and pharmacologic properties of amantadine hydrochloride.
    Toxicology and applied pharmacology, 1969, Volume: 15, Issue:3

    Topics: Abnormalities, Drug-Induced; Acetylcholine; Amantadine; Analgesia; Animals; Arrhythmias, Cardiac; Blood Chemical Analysis; Blood Pressure; Central Nervous System; Depression; Dextroamphetamine; Dogs; Drug Synergism; Electrocardiography; Female; Guinea Pigs; Haplorhini; Heart Rate; Histamine; Horses; Humans; Imipramine; Injections, Intraperitoneal; Injections, Intravenous; Male; Mice; Motor Activity; Nicotine; Norepinephrine; Phenethylamines; Rabbits; Rats; Reproduction; Tetrabenazine; Tritium

1969
[The pharmacologic properties and therapeutic effectiveness of the new antidepressant preparation Azaphen].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1969, Volume: 69, Issue:8

    Topics: Adult; Aged; Amphetamine; Animals; Antidepressive Agents; Bipolar Disorder; Cats; Depression; Depressive Disorder, Major; Dogs; Drug Synergism; Humans; Male; Mice; Middle Aged; Neurocognitive Disorders; Rats; Reserpine; Schizophrenia; Tetrabenazine

1969