Page last updated: 2024-10-20

pyruvic acid and Depression

pyruvic acid has been researched along with Depression in 5 studies

Pyruvic Acid: An intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
pyruvic acid : A 2-oxo monocarboxylic acid that is the 2-keto derivative of propionic acid. It is a metabolite obtained during glycolysis.

Depression: Depressive states usually of moderate intensity in contrast with MAJOR DEPRESSIVE DISORDER present in neurotic and psychotic disorders.

Research Excerpts

ExcerptRelevanceReference
"Depression is a common psychopathological state or mood disorder syndrome."1.72Stable Isotope-Resolved Metabolomics Studies on Corticosteroid-Induced PC12 Cells: A Strategy for Evaluating Glucose Catabolism in an in Vitro Model of Depression. ( Gao, Y; Ling-Hu, T; Liu, SB; Qin, XM; Tian, JS; Wu, WZ; Zhao, YH, 2022)
"Both stroke and depression have independently been associated with pathologically elevated glutamate levels in the brain's extra-cerebral fluid (ECF)."1.51The effect of pyruvate on the development and progression of post-stroke depression: A new therapeutic approach. ( Boyko, M; Brotfain, E; Frank, D; Grinshpun, Y; Gruenbaum, BF; Kuts, R; Natanel, D; Shelef, I; Tsenter, P; Zlotnik, A; Zvenigorodsky, V, 2019)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19902 (40.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (40.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Tian, JS1
Wu, WZ1
Liu, SB1
Ling-Hu, T1
Zhao, YH1
Gao, Y1
Qin, XM1
Frank, D1
Kuts, R1
Tsenter, P1
Gruenbaum, BF1
Grinshpun, Y1
Zvenigorodsky, V1
Shelef, I1
Natanel, D1
Brotfain, E1
Zlotnik, A1
Boyko, M1
Detka, J1
Kurek, A1
Kucharczyk, M1
Głombik, K1
Basta-Kaim, A1
Kubera, M1
Lasoń, W1
Budziszewska, B1
FEATHERSTONE, RM1
CARTER, HR1
GOTTLIEB, JS1
WESTFALL, BA1

Other Studies

5 other studies available for pyruvic acid and Depression

ArticleYear
Stable Isotope-Resolved Metabolomics Studies on Corticosteroid-Induced PC12 Cells: A Strategy for Evaluating Glucose Catabolism in an in Vitro Model of Depression.
    Journal of proteome research, 2022, 03-04, Volume: 21, Issue:3

    Topics: Adrenal Cortex Hormones; Animals; Citric Acid Cycle; Depression; Female; Glucose; Humans; Isotopes;

2022
The effect of pyruvate on the development and progression of post-stroke depression: A new therapeutic approach.
    Neuropharmacology, 2019, 09-01, Volume: 155

    Topics: Animals; Depression; Glutamic Acid; Infarction, Middle Cerebral Artery; Male; Pyruvic Acid; Random A

2019
Brain glucose metabolism in an animal model of depression.
    Neuroscience, 2015, Jun-04, Volume: 295

    Topics: Administration, Oral; Animals; Brain; Depression; Disease Models, Animal; Female; Glucose; Glucoseph

2015
Psychopharmacologic study of schizophrenia and depressions; lactic and pyruvic acid content of the blood before and after administration of sodium amytal.
    Archives of neurology and psychiatry, 1947, Volume: 58, Issue:2

    Topics: Amobarbital; Brain; Depression; Nervous System Physiological Phenomena; Pyruvic Acid; Schizophrenia

1947
Pyruvic acid antagonism to barbiturate depression.
    The Journal of pharmacology and experimental therapeutics, 1946, Volume: 87

    Topics: Barbital; Barbiturates; Depression; Depressive Disorder; Pyruvic Acid

1946