Page last updated: 2024-10-25

amphetamine and Depression

amphetamine has been researched along with Depression in 168 studies

Amphetamine: A powerful central nervous system stimulant and sympathomimetic. Amphetamine has multiple mechanisms of action including blocking uptake of adrenergics and dopamine, stimulation of release of monamines, and inhibiting monoamine oxidase. Amphetamine is also a drug of abuse and a psychotomimetic. The l- and the d,l-forms are included here. The l-form has less central nervous system activity but stronger cardiovascular effects. The d-form is DEXTROAMPHETAMINE.
1-phenylpropan-2-amine : A primary amine that is isopropylamine in which a hydrogen attached to one of the methyl groups has been replaced by a phenyl group.
amphetamine : A racemate comprising equimolar amounts of (R)-amphetamine (also known as levamphetamine or levoamphetamine) and (S)-amphetamine (also known as dexamfetamine or dextroamphetamine.

Depression: Depressive states usually of moderate intensity in contrast with MAJOR DEPRESSIVE DISORDER present in neurotic and psychotic disorders.

Research Excerpts

ExcerptRelevanceReference
"Prescription amphetamines are utilized for treatment of depression in older adults, yet cardiovascular risks in this population are not well described."8.12Cardiovascular Outcomes Among Older Individuals With Depression Prescribed Amphetamines: A Retrospective Cohort Study. ( Bone, C; Clegg, TJ; Latronica, JR; Silvis, ML; Tuan, WJ, 2022)
" The present report deals with the effects of imipramine and mianserine on two animal models of depression, after acute or prolonged previous treatment with these antidepressants."7.68Lack of tolerance to imipramine or mianserine in two animal models of depression. ( Barros, HM; Tannhauser, M; Wainstein, M, 1990)
"Seventy unwed pregnant patients in states of mild to moderate depression evidenced by one or more symptoms (tenseness, "nervousness," crying spells, listlessness, fatigue, nausea and vomiting, insomnia and overeating), received informal psychotherapy and a sustained-release capsule combining d-amphetamine sulfate and amobarbital."7.63Prepartum depression; a study of seventy unwed mothers treated with d-amphetamine sulfate and amobarbital. ( CALDWELL, WG; NOWERS, W, 1958)
"Schizophrenia is a chronic mental disorder related to hypo-functioning of glutamatergic neurotransmission."5.40A novel analog of olanzapine linked to sarcosinyl moiety (PGW5) demonstrates high efficacy and good safety profile in mouse models of schizophrenia. ( Bidder, M; Gil-Ad, I; Kramer, M; Portnoy, M; Taler, M; Tarasenko, I; Weizman, A, 2014)
"Myo-inositol is an important precursor in cellular second-messenger synthesis."5.29The effect of peripheral inositol injection on rat motor activity models of depression. ( Alpert, C; Belmaker, RH; Bersudsky, Y; Kofman, O; Vinnitsky, I, 1993)
" We assessed changes in [(11)C]-raclopride binding potential (BP) using positron emission tomography (PET) before and after the oral administration of d-amphetamine in healthy controls and unmedicated patients with current depression with and without current tobacco dependence."5.14Dopaminergic activity in depressed smokers: a positron emission tomography study. ( Busto, UE; Houle, S; Kapur, S; Mayberg, H; Redden, L; Zawertailo, LA, 2009)
"The use of traditional psychostimulants (methylphenidate and dexamphetamine) and stimulant-like drugs (modafinil and armodafinil) for the treatment of depression is a growing concern given the lack of research evidence supporting their effectiveness."4.93Stimulants for depression: On the up and up? ( Bassett, D; Boyce, P; Byrow, Y; Hopwood, M; Lyndon, W; Malhi, GS; Mulder, R; Murray, G; Porter, R; Singh, A, 2016)
"Prescription amphetamines are utilized for treatment of depression in older adults, yet cardiovascular risks in this population are not well described."4.12Cardiovascular Outcomes Among Older Individuals With Depression Prescribed Amphetamines: A Retrospective Cohort Study. ( Bone, C; Clegg, TJ; Latronica, JR; Silvis, ML; Tuan, WJ, 2022)
"Via linkage of the Danish nationwide health registers, we identified all patients with a diagnosis of depression initiating stimulants, including methylphenidate, modafinil, amphetamine, dexamphetamine or lisdexamphetamine, from 1995 to 2012."3.96The use of stimulants in depression: Results from a self-controlled register study. ( Brink, P; Nielsen, J; Rohde, C; Østergaard, SD, 2020)
"Abrupt discontinuation of chronic amphetamine consumption leads to withdrawal symptoms including depression, anhedonia, dysphoria, fatigue, and anxiety."3.88Involvement of NO/NMDA-R pathway in the behavioral despair induced by amphetamine withdrawal. ( Afshari, K; Amini-Khoei, H; Amiri, S; Dehpour, AR; Ghesmati, M; Haj-Mirzaian, A; Hashemiaghdam, A; Ramezanzadeh, K, 2018)
"Administration of amphetamine (AMPH) can induce symptoms of psychosis in humans and locomotor sensitization in rats; in contrast, withdrawal from a period of AMPH intake is most often associated with symptoms of human endogenous depression."3.72Amphetamine withdrawal does not produce a depressive-like state in rats as measured by three behavioral tests. ( Feldon, J; Murphy, CA; Nanz-Bahr, NI; Pezze, MA; Pryce, CR; Russig, H, 2003)
"Withdrawal from chronic amphetamine administration results in behavioral changes that may be analogous to some aspects of depression in humans, such as reward deficits (i."3.72Withdrawal from chronic amphetamine induces depressive-like behavioral effects in rodents. ( Cryan, JF; Hoyer, D; Markou, A, 2003)
"The symptom of "diminished interest or pleasure" in rewarding stimuli is an affective symptom of nicotine and amphetamine withdrawal, and a core symptom of depression."3.71Fluoxetine combined with a serotonin-1A receptor antagonist reversed reward deficits observed during nicotine and amphetamine withdrawal in rats. ( Harrison, AA; Liem, YT; Markou, A, 2001)
"The study of the effects of repeated amphetamine administration and withdrawal on brain reward function has relevance to both amphetamine dependence and non-drug-induced depressions."3.70Effects of repeated withdrawal from continuous amphetamine administration on brain reward function in rats. ( Markou, A; Myers, C; Paterson, NE, 2000)
" The present report deals with the effects of imipramine and mianserine on two animal models of depression, after acute or prolonged previous treatment with these antidepressants."3.68Lack of tolerance to imipramine or mianserine in two animal models of depression. ( Barros, HM; Tannhauser, M; Wainstein, M, 1990)
"A controlled study of 101 patients indicated that a combination of amphetamine and Rauwolfia was effective in the treatment of prepartum nausea and vomiting."3.63Prepartum nausea and vomiting; a new approach to treatment. ( CALDWELL, WG; HOBBS, K, 1958)
"Seventy unwed pregnant patients in states of mild to moderate depression evidenced by one or more symptoms (tenseness, "nervousness," crying spells, listlessness, fatigue, nausea and vomiting, insomnia and overeating), received informal psychotherapy and a sustained-release capsule combining d-amphetamine sulfate and amobarbital."3.63Prepartum depression; a study of seventy unwed mothers treated with d-amphetamine sulfate and amobarbital. ( CALDWELL, WG; NOWERS, W, 1958)
"Some evidence indicates that bipolar depression may be more responsive to dopaminergic agents, suggesting that adjunctive stimulant medication may be an effective treatment for bipolar depression as well as for medication-induced sedation."2.71Adjunctive stimulant use in patients with bipolar disorder: treatment of residual depression and sedation. ( Carlson, PJ; Merlock, MC; Suppes, T, 2004)
"d-Amphetamine was 2 to 2."2.64Attenuation of the euphoriant and activating effects of d- and l-amphetamine by lithium carbonate treatment. ( Murphy, DL; Van Kammen, DP, 1975)
"Overall, 319 individuals with substance use disorders (273 males) with a mean (± SD) age of 42."1.72Temporal associations between depressive features and self-stigma in people with substance use disorders related to heroin, amphetamine, and alcohol use: a cross-lagged analysis. ( Chang, CW; Chang, KC; Chen, IH; Chen, JS; Huang, SW; Lin, CY; Liu, CH; Potenza, MN; Saffari, M, 2022)
"Tranylcypromine is an effective antidepressant from the class of monoamine oxidase inhibitors and is structurally related to amphetamine."1.46Discrimination Between Drug Abuse and Medical Therapy: Case report of a tranylcypromine overdose-related fatality. ( Akhgari, M; Etemadi-Aleagha, A; Ghasemi, A; Jokar, F, 2017)
"Schizophrenia is a chronic mental disorder related to hypo-functioning of glutamatergic neurotransmission."1.40A novel analog of olanzapine linked to sarcosinyl moiety (PGW5) demonstrates high efficacy and good safety profile in mouse models of schizophrenia. ( Bidder, M; Gil-Ad, I; Kramer, M; Portnoy, M; Taler, M; Tarasenko, I; Weizman, A, 2014)
"Amphetamine has a significant potential for abuse and addiction."1.39Abstinence from repeated amphetamine treatment induces depressive-like behaviors and oxidative damage in rat brain. ( Andreazza, AC; Che, Y; Cui, YH; Tan, H; Wang, JF; Young, LT, 2013)
"Depression is the most common psychiatric complication in Parkinson's disease (PD)."1.34Lesions of dopaminergic neurons in the substantia nigra pars compacta and in the ventral tegmental area enhance depressive-like behavior in rats. ( Juckel, G; Klein, J; Kupsch, A; Lee, T; Morgenstern, R; Mundt, A; Petrus, D; von Rumohr, A; Winter, C, 2007)
"Myo-inositol is an important precursor in cellular second-messenger synthesis."1.29The effect of peripheral inositol injection on rat motor activity models of depression. ( Alpert, C; Belmaker, RH; Bersudsky, Y; Kofman, O; Vinnitsky, I, 1993)
"This article focuses on the treatment of depression with special reference to pharmacotherapy."1.26The pharmacologic treatment of depression. ( Denber, HC, 1979)

Research

Studies (168)

TimeframeStudies, this research(%)All Research%
pre-1990129 (76.79)18.7374
1990's6 (3.57)18.2507
2000's14 (8.33)29.6817
2010's15 (8.93)24.3611
2020's4 (2.38)2.80

Authors

AuthorsStudies
Latronica, JR1
Tuan, WJ1
Clegg, TJ1
Silvis, ML1
Bone, C1
Saffari, M1
Chang, KC1
Chen, JS1
Chang, CW1
Chen, IH1
Huang, SW1
Liu, CH1
Lin, CY1
Potenza, MN1
Fu, YP1
Wang, Y1
Rohde, C1
Brink, P1
Østergaard, SD1
Nielsen, J1
Akhgari, M1
Jokar, F1
Etemadi-Aleagha, A1
Ghasemi, A1
Haj-Mirzaian, A2
Amiri, S1
Amini-Khoei, H1
Hashemiaghdam, A1
Ramezanzadeh, K1
Ghesmati, M1
Afshari, K1
Dehpour, AR1
Bananej, A1
Völkl-Kernstock, S1
Lesch, O1
Walter, H1
Skala, K1
Kim, W1
Won, SY1
Yoon, BJ1
Bao, YP1
Qiu, Y1
Yan, SY1
Jia, ZJ1
Li, SX1
Lian, Z1
Mu, Y1
Liu, ZM1
Gil-Ad, I1
Portnoy, M1
Tarasenko, I1
Bidder, M1
Kramer, M1
Taler, M1
Weizman, A1
Yu, Q1
Teixeira, CM1
Mahadevia, D1
Huang, Y1
Balsam, D1
Mann, JJ1
Gingrich, JA1
Ansorge, MS1
Fulde, GW1
Forster, SL1
Malhi, GS1
Byrow, Y1
Bassett, D1
Boyce, P1
Hopwood, M1
Lyndon, W1
Mulder, R1
Porter, R1
Singh, A1
Murray, G1
Marszalek-Grabska, M1
Gibula-Bruzda, E1
Jenda, M1
Gawel, K1
Kotlinska, JH1
Bespalov, AY1
van Gaalen, MM1
Sukhotina, IA1
Wicke, K1
Mezler, M1
Schoemaker, H1
Gross, G1
Busto, UE1
Redden, L1
Mayberg, H1
Kapur, S1
Houle, S1
Zawertailo, LA1
Romeas, T1
Morissette, MC1
Mnie-Filali, O1
Piñeyro, G1
Boye, SM1
RUDOLF, GD1
Der-Avakian, A1
Markou, A4
Wesołowska, A1
Partyka, A1
Jastrzębska-Więsek, M1
Kolarz, A1
Mierzejewski, P1
Bieńkowski, P1
Kołaczkowski, M1
Iezhitsa, IN1
Spasov, AA1
Kharitonova, MV1
Kravchenko, MS1
Casas, S1
García, S1
Cabrera, R1
Nanfaro, F1
Escudero, C1
Yunes, R1
Che, Y1
Cui, YH1
Tan, H1
Andreazza, AC1
Young, LT1
Wang, JF1
Holmes, PV1
Masini, CV1
Primeaux, SD1
Garrett, JL1
Zellner, A1
Stogner, KS1
Duncan, AA1
Crystal, JD1
Alcaro, A1
Cabib, S1
Ventura, R1
Puglisi-Allegra, S1
Russig, H1
Pezze, MA1
Nanz-Bahr, NI1
Pryce, CR1
Feldon, J1
Murphy, CA1
Cryan, JF1
Hoyer, D1
LEHEW, JL1
GALLINEK, A1
ROBERTS, E1
GRAHN, HV2
COHEN, BD1
SENF, R2
HUSTON, PE2
DE RUDOLF, GM1
SETTEL, E1
CALDWELL, WG2
HOBBS, K1
NOWERS, W1
DAVIDOFF, E1
LEMERE, F1
KLIMO, Z1
KARKOSKA, V1
LUKASSIEWICZ, M1
BUSHNELL, LF1
HARRIS, LS2
UHLE, FC1
TEBROCK, HE1
YOUNG, W1
O'DONNELL, W1
KAUFMAN, M1
FEIGLEY, DM1
GIBERTI, F2
ROSSI, R2
BATTISTELLA, G1
HARE, EH1
DOMINIAN, J1
SHARPE, L1
STEIN, L1
HARRISON, RM1
SIEGLER, PE1
BATTERMAN, RC1
FELLNER, CH1
RECH, RH1
CLANCY, J1
LAPOLLA, A1
NASH, LR1
FISCHER, E1
ORLANDO, J1
LUDMER, RL1
PARE, CM1
LEWIS, E1
ANCHERSEN, P1
JOHNSEN, G1
Carlson, PJ1
Merlock, MC1
Suppes, T1
HOLLISTER, LE1
PRUSMACK, JJ1
Mällo, T1
Alttoa, A1
Kõiv, K1
Tõnissaar, M1
Eller, M1
Harro, J1
Winter, C1
von Rumohr, A1
Mundt, A1
Petrus, D1
Klein, J1
Lee, T1
Morgenstern, R1
Kupsch, A1
Juckel, G1
Siuciak, JA1
McCarthy, SA1
Chapin, DS1
Martin, AN1
Harms, JF1
Schmidt, CJ1
GOTTLIEB, JS1
Seelye, EE1
Varga, E1
Tringer, L1
Reisine, T1
Johnson, R1
Wiech, N1
Ursillo, R1
Yamamura, HI1
Reisberg, B1
Ferris, SH1
Gershon, S3
Antelman, SM1
Chiodo, LA1
DeGiovanni, LA1
Katz, RJ1
Roth, KA1
Schmaltz, K1
Kofman, O1
Bersudsky, Y1
Vinnitsky, I1
Alpert, C1
Belmaker, RH1
West, CH1
Bonsall, RW1
Emery, MS1
Weiss, JM1
Weintraub, D1
Linder, MW1
Paterson, NE1
Myers, C1
Harrison, AA1
Liem, YT1
Van Kammen, DP3
Murphy, DL3
Denber, HC1
Sachar, EJ1
Spencer, PS1
Buchsbaum, MS1
Binks, SM1
Murchie, JK1
Greenwood, DT1
McLellan, AT1
Druley, KA1
Reuter, CJ1
Beckmann, H1
Goodwin, FK1
Brook, R1
Szandorowska, B1
Whitehead, PC1
Langer, G1
Heinze, G1
Reim, B1
Matussek, N1
Woody, GE1
O'Brien, CP1
Rickels, K1
Siever, L1
Kraemer, H1
Sack, R1
Angwin, P1
Berger, P1
Zarcone, V1
Barchas, J1
Brodie, HK1
Boyd, P1
Singh, V1
Khanna, R1
Srivastava, VK1
Palit, G1
Shanker, K1
Carlson, JN1
Glick, SD1
Bennett, G1
Rigby, K1
Wainstein, M1
Tannhauser, M1
Barros, HM1
Koella, WP1
Caldecott-Hazard, S1
Mazziotta, J1
Phelps, M1
Burov, IuV1
Kampov-Polevoĭ, AV1
Nikitina, LN1
Schildkraut, JJ4
Watson, R2
Draskoczy, PR1
Schmidt, CW1
Jefferson, JW1
Ginestet, D1
Rosen, S1
Martorano, J1
Hartmann, E3
Guilleminault, C1
Carskadon, M1
Dement, WC1
Aceto, MD1
Lesher, GY1
Pearl, J1
Brown, TG1
Ferrini, R1
Miragoli, G1
Croce, G1
Schnee, J1
Bilikiewicz, A1
Góra, S1
Burke, EL1
Eichberg, RH1
Pearlman, CA1
Greenberg, R1
Heller, ME1
Mordkoff, AM1
Henriques, E1
Arsenian, J1
Cutter, H1
Samaraweera, AB1
Klerman, GL1
Kipperman, A1
Fine, EW1
Wallace, D1
Hiner, D1
Angrist, B1
Sathananthan, G1
Wilk, S1
van Praag, HM3
Korf, J2
Enelow, AJ1
Lapin, IP1
Arnold, LE1
Strobl, D1
Weisenberg, A1
Axelrod, J1
Müller-Oswald, U1
Ruppen, R1
Baumann, U1
Angst, J1
Green, RS1
Rau, JH1
Klein, DF1
Nail, RL1
Gunderson, EK1
Kolb, D1
Lehmann, HE1
Rysánek, K1
Stone, WN1
Hofling, CK1
Winslow, WW1
Cole, JO1
Stern, H1
Mashkovskiĭ, MD2
Davis, JM1
Park, LC1
Imboden, JB1
van Woudenberg, F1
Goldstein, BJ1
Brauzer, B1
Gardner, R1
Connell, PH1
Florio, V1
Fuentes, JA1
Ziegler, H1
Longo, VG1
Gunne, LM1
Holmgren, P1
Lindquist, O1
Saldeen, T1
Tinklenberg, JR1
Iriye, TT1
Simmonds, FA1
Polezhaeva, AI1
Avrutskii, GIa1
Vertozgadova, OP1
Smulevich, AB1
Paulshock, BZ1
Callaway, E1
Fischer, A1
Guerrant, J1
Murphey, BG1
Weinstein, MR1
Johnson, MH1
Edison, GR1
Traugott, NN1
Kaufman, DA1
Schut, T1
Bosma, E1
van den Bergh, R1
Marino, A1
Lloyd, G1
Dasberg, H1
Feldman, S1
Hekimian, LJ1
Hubin, P2
Servais, J2
Pelczarska, A1
McNair, FE1
Johnson, J1
Milner, G1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Neuroactive Steroids in Acute Ischemic Stroke: Association With Cognitive, Functional and Neurological Outcomes.[NCT02914106]60 participants (Actual)Observational2014-06-30Completed
Changes in Plasma Cortisol, Brain-derived Neurotrophic Factor, and Nitrites in Patients With Acute Ischemic Stroke[NCT03242304]40 participants (Actual)Observational2016-04-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

24 reviews available for amphetamine and Depression

ArticleYear
Amphetamines abuse and depression: Focus on TRPC channels.
    Experimental neurology, 2023, Volume: 364

    Topics: Amphetamine; Amphetamines; Central Nervous System Stimulants; Depression; Methamphetamine; Transient

2023
The impact of amphetamine-type stimulants on emergency services.
    Current opinion in psychiatry, 2015, Volume: 28, Issue:4

    Topics: Acute Disease; Aggression; Amphetamine; Amphetamine-Related Disorders; Anxiety; Central Nervous Syst

2015
Stimulants for depression: On the up and up?
    The Australian and New Zealand journal of psychiatry, 2016, Volume: 50, Issue:3

    Topics: Amphetamine; Antidepressive Agents; Benzhydryl Compounds; Bipolar Disorder; Central Nervous System S

2016
CURRENT STATUS OF DRUG TREATMENT IN THE DEPRESSIVE STATE.
    The Medical clinics of North America, 1964, Volume: 48

    Topics: Amitriptyline; Amphetamine; Amphetamines; Antidepressive Agents; Aspartic Acid; Benactyzine; Classif

1964
Pharmacotherapy of senile dementia.
    Proceedings of the annual meeting of the American Psychopathological Association, 1980, Volume: 69

    Topics: Adult; Age Factors; Aged; Alzheimer Disease; Amphetamine; Antidepressive Agents, Tricyclic; Dementia

1980
Evidence for neuroendocrine abnormalities in the major mental illnesses.
    Research publications - Association for Research in Nervous and Mental Disease, 1975, Volume: 54

    Topics: Adrenocorticotropic Hormone; Aged; Amphetamine; Bipolar Disorder; Chlorpromazine; Circadian Rhythm;

1975
Review of the pharmacology of existing antidepressants.
    British journal of clinical pharmacology, 1977, Volume: 4Suppl 2

    Topics: Amphetamine; Animals; Antidepressive Agents; Brain; Catecholamines; Depression; Humans; Imipramine;

1977
A review of the CNS effects of fenfluramine, 780SE and norfenfluramine on animals and man.
    Postgraduate medical journal, 1975, Volume: 51 Suppl 1

    Topics: Acetylcholine; Amphetamine; Analgesia; Animals; Behavior; Biogenic Amines; Body Temperature Regulati

1975
CNS-related (side-)effects of beta-blockers with special reference to mechanisms of action.
    European journal of clinical pharmacology, 1985, Volume: 28 Suppl

    Topics: Adrenergic beta-Antagonists; Amphetamine; Animals; Anxiety; Blood-Brain Barrier; Central Nervous Sys

1985
Beta-adrenergic receptor blocking drugs in psychiatry.
    Archives of general psychiatry, 1974, Volume: 31, Issue:5

    Topics: Acute Disease; Adrenergic beta-Antagonists; Alcoholism; Amphetamine; Animals; Antidepressive Agents;

1974
The D-state and norepinephrine-dependent systems.
    International psychiatry clinics, 1970, Volume: 7, Issue:2

    Topics: Adult; Amphetamine; Animals; Attention; Brain; Brain Chemistry; Cats; Child; Depression; Feedback; H

1970
Medical-psychological implications of recent sleep research.
    Psychiatry in medicine, 1970, Volume: 1, Issue:4

    Topics: Adaptation, Psychological; Amphetamine; Barbiturates; Central Nervous System Stimulants; Chloral Hyd

1970
Drug therapoy of clinical depressions--current status and implications for research on neuropharmacology of the affective disorders.
    Journal of psychiatric research, 1972, Volume: 9, Issue:3

    Topics: Adjustment Disorders; Affective Symptoms; Amphetamine; Antidepressive Agents; Antipsychotic Agents;

1972
The use and abuse of the psychotropic drugs.
    The Journal of the Oklahoma State Medical Association, 1973, Volume: 66, Issue:8

    Topics: Adult; Amphetamine; Antidepressive Agents; Anxiety; Chlorpromazine; Depression; Drug Utilization; Fe

1973
Kynurenines as probable participants of depression.
    Pharmakopsychiatrie, Neuro-Psychopharmakologie, 1973, Volume: 6, Issue:6

    Topics: 5-Hydroxytryptophan; Amphetamine; Animals; Behavior; Blood Pressure; Body Temperature; Depression; D

1973
[Recent knowledge on the biochemical effects of antidepressive agents].
    Activitas nervosa superior, 1968, Volume: 10, Issue:1

    Topics: Amines; Amphetamine; Animals; Antidepressive Agents; Catecholamines; Cell Membrane; Depression; Huma

1968
Drug therapy.
    Progress in neurology and psychiatry, 1968, Volume: 23

    Topics: Amphetamine; Animals; Antidepressive Agents; Bipolar Disorder; Butyrophenones; Chlorprothixene; Clin

1968
Neuropsychopharmacology and the affective disorders. (Third of three parts)
    The New England journal of medicine, 1969, Aug-07, Volume: 281, Issue:6

    Topics: Affective Symptoms; Amines; Amphetamine; Animals; Antidepressive Agents; Brain; Catecholamines; Coca

1969
Psychopharmacology and psychopathology.
    Proceedings of the annual meeting of the American Psychopathological Association, 1969, Volume: 58

    Topics: Amphetamine; Barbiturates; Catatonia; Depression; Humans; Mental Disorders; Neurotic Disorders; Para

1969
Serotonin, and its effects on the pituitary-adrenal axis in depression.
    The Chicago Medical School quarterly, 1970, Volume: 29, Issue:1

    Topics: Amphetamine; Animals; Behavior, Animal; Brain Chemistry; Depression; Humans; Hypothalamus; Mental Di

1970
[Adrenergic mechanisms of antidepressant action].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1970, Volume: 70, Issue:5

    Topics: Amphetamine; Animals; Antidepressive Agents; Brain; Brain Chemistry; Cats; Depression; Dogs; Humans;

1970
Theories of biological etiology of affective disorders.
    International review of neurobiology, 1970, Volume: 12

    Topics: Adrenal Cortex Hormones; Affective Symptoms; Amines; Amphetamine; Antidepressive Agents; Bipolar Dis

1970
Clinical and heuristic value of clinical drug research.
    The Journal of nervous and mental disease, 1970, Volume: 151, Issue:5

    Topics: Affective Symptoms; Amitriptyline; Amphetamine; Butyrophenones; Child Behavior Disorders; Chlorproma

1970
Pharmacologic considerations in the treatment of anxiety and depression in medical practice.
    The Medical clinics of North America, 1971, Volume: 55, Issue:2

    Topics: Adult; Amphetamine; Antidepressive Agents; Anxiety; Autonomic Nervous System; Cardiovascular System;

1971

Trials

13 trials available for amphetamine and Depression

ArticleYear
Dopaminergic activity in depressed smokers: a positron emission tomography study.
    Synapse (New York, N.Y.), 2009, Volume: 63, Issue:8

    Topics: Adolescent; Adult; Age Factors; Aged; Amphetamine; Binding, Competitive; Depression; Dopamine; Dopam

2009
Adjunctive stimulant use in patients with bipolar disorder: treatment of residual depression and sedation.
    Bipolar disorders, 2004, Volume: 6, Issue:5

    Topics: Adult; Aged; Amphetamine; Antipsychotic Agents; Bipolar Disorder; Central Nervous System Stimulants;

2004
Attenuation of the euphoriant and activating effects of d- and l-amphetamine by lithium carbonate treatment.
    Psychopharmacologia, 1975, Nov-21, Volume: 44, Issue:3

    Topics: Adult; Amphetamine; Bipolar Disorder; Depression; Dextroamphetamine; Euphoria; Female; Humans; Hydro

1975
Individual differences in average evoked responses to d- and l-amphetamine with and without lithium carbonate in depressed patients.
    Psychopharmacology, 1977, Jan-31, Volume: 51, Issue:2

    Topics: Adult; Amphetamine; Blood Platelets; Depression; Dextroamphetamine; Drug Interactions; Drug Therapy,

1977
Urinary excretion of 3-methoxy-4-hydroxyphenylglycol in depressed patients: modifications by amphetamine and lithium.
    Biological psychiatry, 1976, Volume: 11, Issue:4

    Topics: Adult; Amphetamine; Clinical Trials as Topic; Depression; Drug Therapy, Combination; Euphoria; Femal

1976
Depression and anxiety in heroin addicts: a placebo-controlled study of doxepin in combination with methadone.
    The American journal of psychiatry, 1975, Volume: 132, Issue:4

    Topics: Administration, Oral; Adult; Alcoholic Intoxication; Amphetamine; Anxiety; Barbiturates; Capsules; C

1975
Beta-adrenergic receptor blocking drugs in psychiatry.
    Archives of general psychiatry, 1974, Volume: 31, Issue:5

    Topics: Acute Disease; Adrenergic beta-Antagonists; Alcoholism; Amphetamine; Animals; Antidepressive Agents;

1974
4-Chloramphetamines. Chance and trend in the development of new antidepressants.
    The Journal of clinical pharmacology and new drugs, 1973, Volume: 13, Issue:1

    Topics: Amines; Amphetamine; Antidepressive Agents; Behavior; Brain Chemistry; Carbon Isotopes; Chlorine; Cl

1973
Hyperkinetic adult. Study of the "paradoxical" amphetamine response.
    JAMA, 1972, Nov-06, Volume: 222, Issue:6

    Topics: Adult; Age Factors; Amphetamine; Anxiety; Depression; Dextroamphetamine; Humans; Hyperkinesis; Male;

1972
Drug therapy.
    Progress in neurology and psychiatry, 1968, Volume: 23

    Topics: Amphetamine; Animals; Antidepressive Agents; Bipolar Disorder; Butyrophenones; Chlorprothixene; Clin

1968
Clinical and heuristic value of clinical drug research.
    The Journal of nervous and mental disease, 1970, Volume: 151, Issue:5

    Topics: Affective Symptoms; Amitriptyline; Amphetamine; Butyrophenones; Child Behavior Disorders; Chlorproma

1970
Investigation into the possible influence of chlorinated amphetamine derivatives on 5-hydroxytryptamine synthesis in man.
    Psychopharmacologia, 1970, Volume: 18, Issue:4

    Topics: 5-Hydroxytryptophan; Amphetamine; Antidepressive Agents; Brain; Carbon Isotopes; Clinical Trials as

1970
On the pharmacology of dreaming sleep. (The D state).
    The Journal of nervous and mental disease, 1968, Volume: 146, Issue:2

    Topics: Adaptation, Psychological; Adult; Amphetamine; Antidepressive Agents; Atropine; Barbiturates; Depres

1968

Other Studies

134 other studies available for amphetamine and Depression

ArticleYear
Cardiovascular Outcomes Among Older Individuals With Depression Prescribed Amphetamines: A Retrospective Cohort Study.
    The journals of gerontology. Series A, Biological sciences and medical sciences, 2022, 12-29, Volume: 77, Issue:12

    Topics: Aged; Amphetamine; Amphetamines; Cardiovascular Diseases; Central Nervous System Stimulants; Cohort

2022
Temporal associations between depressive features and self-stigma in people with substance use disorders related to heroin, amphetamine, and alcohol use: a cross-lagged analysis.
    BMC psychiatry, 2022, 12-21, Volume: 22, Issue:1

    Topics: Adult; Amphetamine; Cross-Sectional Studies; Depression; Heroin; Humans; Male; Middle Aged; Social S

2022
The use of stimulants in depression: Results from a self-controlled register study.
    The Australian and New Zealand journal of psychiatry, 2020, Volume: 54, Issue:8

    Topics: Adult; Amphetamine; Central Nervous System Stimulants; Denmark; Depression; Dextroamphetamine; Drug

2020
Discrimination Between Drug Abuse and Medical Therapy: Case report of a tranylcypromine overdose-related fatality.
    Sultan Qaboos University medical journal, 2017, Volume: 17, Issue:2

    Topics: Adult; Amphetamine; Antidepressive Agents; Central Nervous System Stimulants; Depression; Drug Overd

2017
Involvement of NO/NMDA-R pathway in the behavioral despair induced by amphetamine withdrawal.
    Brain research bulletin, 2018, Volume: 139

    Topics: Amphetamine; Analysis of Variance; Animals; Central Nervous System Stimulants; Depression; Disease M

2018
No evidence of subgroups found in amphetamine consumers in Iran.
    Neuropsychiatrie : Klinik, Diagnostik, Therapie und Rehabilitation : Organ der Gesellschaft Osterreichischer Nervenarzte und Psychiater, 2018, Volume: 32, Issue:2

    Topics: Amphetamine; Anxiety; Depression; Drug Users; Humans; Iran; Substance-Related Disorders

2018
CRMP2 mediates GSK3β actions in the striatum on regulating neuronal structure and mania-like behavior.
    Journal of affective disorders, 2019, 02-15, Volume: 245

    Topics: Amphetamine; Animals; Bipolar Disorder; Cells, Cultured; Corpus Striatum; Dendrites; Depression; Dis

2019
Pattern of drug use and depressive symptoms among amphetamine type stimulants users in Beijing and Guangdong province, China.
    PloS one, 2013, Volume: 8, Issue:4

    Topics: Adult; Alcohol Drinking; Amphetamine; Central Nervous System Stimulants; China; Comorbidity; Cross-S

2013
A novel analog of olanzapine linked to sarcosinyl moiety (PGW5) demonstrates high efficacy and good safety profile in mouse models of schizophrenia.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2014, Volume: 24, Issue:3

    Topics: Alanine; Amphetamine; Animals; Antipsychotic Agents; Anxiety; Benzodiazepines; Brain; Central Nervou

2014
Dopamine and serotonin signaling during two sensitive developmental periods differentially impact adult aggressive and affective behaviors in mice.
    Molecular psychiatry, 2014, Volume: 19, Issue:6

    Topics: 3,4-Dihydroxyphenylacetic Acid; Affect; Aggression; Amphetamine; Animals; Anxiety; Brain; Central Ne

2014
Memantine improves memory impairment and depressive-like behavior induced by amphetamine withdrawal in rats.
    Brain research, 2016, 07-01, Volume: 1642

    Topics: Amphetamine; Amphetamine-Related Disorders; Animals; Antidepressive Agents; Central Nervous System S

2016
Behavioral characterization of the mGlu group II/III receptor antagonist, LY-341495, in animal models of anxiety and depression.
    European journal of pharmacology, 2008, Sep-11, Volume: 592, Issue:1-3

    Topics: Amino Acids; Amphetamine; Animals; Anti-Anxiety Agents; Antidepressive Agents, Second-Generation; An

2008
Simultaneous anhedonia and exaggerated locomotor activation in an animal model of depression.
    Psychopharmacology, 2009, Volume: 205, Issue:2

    Topics: Amphetamine; Analgesics, Non-Narcotic; Analysis of Variance; Animals; Body Weight; Central Nervous S

2009
The effect of amphetamine on fatigue and depression.
    The British journal of addiction to alcohol and other drugs, 1947, Volume: 44, Issue:2

    Topics: Amphetamine; Amphetamines; Depression; Depressive Disorder; Fatigue; Humans

1947
Withdrawal from chronic exposure to amphetamine, but not nicotine, leads to an immediate and enduring deficit in motivated behavior without affecting social interaction in rats.
    Behavioural pharmacology, 2010, Volume: 21, Issue:4

    Topics: Amphetamine; Animals; Body Weight; Central Nervous System Stimulants; Conditioning, Operant; Depress

2010
Tail suspension test does not detect antidepressant-like properties of atypical antipsychotics.
    Behavioural pharmacology, 2011, Volume: 22, Issue:1

    Topics: Amphetamine; Animals; Antidepressive Agents; Antipsychotic Agents; Behavior, Animal; Central Nervous

2011
Effect of magnesium chloride on psychomotor activity, emotional status, and acute behavioural responses to clonidine, d-amphetamine, arecoline, nicotine, apomorphine, and L-5-hydroxytryptophan.
    Nutritional neuroscience, 2011, Volume: 14, Issue:1

    Topics: 5-Hydroxytryptophan; Amphetamine; Animals; Anxiety; Apomorphine; Arecoline; Clonidine; Depression; D

2011
Progesterone prevents depression-like behavior in a model of Parkinson's disease induced by 6-hydroxydopamine in male rats.
    Pharmacology, biochemistry, and behavior, 2011, Volume: 99, Issue:4

    Topics: Amphetamine; Animals; Antidepressive Agents; Apomorphine; Cues; Depression; Dopamine Agonists; Male;

2011
Progesterone prevents depression-like behavior in a model of Parkinson's disease induced by 6-hydroxydopamine in male rats.
    Pharmacology, biochemistry, and behavior, 2011, Volume: 99, Issue:4

    Topics: Amphetamine; Animals; Antidepressive Agents; Apomorphine; Cues; Depression; Dopamine Agonists; Male;

2011
Progesterone prevents depression-like behavior in a model of Parkinson's disease induced by 6-hydroxydopamine in male rats.
    Pharmacology, biochemistry, and behavior, 2011, Volume: 99, Issue:4

    Topics: Amphetamine; Animals; Antidepressive Agents; Apomorphine; Cues; Depression; Dopamine Agonists; Male;

2011
Progesterone prevents depression-like behavior in a model of Parkinson's disease induced by 6-hydroxydopamine in male rats.
    Pharmacology, biochemistry, and behavior, 2011, Volume: 99, Issue:4

    Topics: Amphetamine; Animals; Antidepressive Agents; Apomorphine; Cues; Depression; Dopamine Agonists; Male;

2011
Abstinence from repeated amphetamine treatment induces depressive-like behaviors and oxidative damage in rat brain.
    Psychopharmacology, 2013, Volume: 227, Issue:4

    Topics: Amphetamine; Amphetamine-Related Disorders; Animals; Behavior, Animal; Brain; Depression; Disease Mo

2013
Intravenous self-administration of amphetamine is increased in a rat model of depression.
    Synapse (New York, N.Y.), 2002, Volume: 46, Issue:1

    Topics: Amphetamine; Amphetamine-Related Disorders; Analysis of Variance; Animals; Behavior, Animal; Central

2002
Genotype- and experience-dependent susceptibility to depressive-like responses in the forced-swimming test.
    Psychopharmacology, 2002, Volume: 164, Issue:2

    Topics: Adrenergic Uptake Inhibitors; Amphetamine; Analysis of Variance; Animals; Antidepressive Agents, Tri

2002
Amphetamine withdrawal does not produce a depressive-like state in rats as measured by three behavioral tests.
    Behavioural pharmacology, 2003, Volume: 14, Issue:1

    Topics: Adrenocorticotropic Hormone; Amphetamine; Animals; Behavior, Animal; Central Nervous System Stimulan

2003
Withdrawal from chronic amphetamine induces depressive-like behavioral effects in rodents.
    Biological psychiatry, 2003, Jul-01, Volume: 54, Issue:1

    Topics: Amphetamine; Amphetamine-Related Disorders; Animals; Behavior, Animal; Central Nervous System Stimul

2003
Amycal comp.
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1953, 02-01, Volume: 73, Issue:3

    Topics: Amphetamine; Amphetamines; Atropa belladonna; Barbiturates; Depression; Depressive Disorder

1953
Evaluation of an amphetamine-barbiturate combination in the supportive treatment of the aged.
    Journal of the American Geriatrics Society, 1954, Volume: 2, Issue:2

    Topics: Aged; Amphetamine; Amphetamines; Anxiety; Barbiturates; Depression; Depressive Disorder; Humans

1954
Syndrome of episodes of hypersomnia, bulimia, and abnormal mental states.
    Journal of the American Medical Association, 1954, Mar-27, Volume: 154, Issue:13

    Topics: Amphetamine; Amphetamines; Bulimia; Depression; Disorders of Excessive Somnolence; Humans; Hunger; M

1954
D'amphetamine therapy in obesity or depression complicated by benign hypertension.
    American practitioner and digest of treatment, 1954, Volume: 5, Issue:8

    Topics: Amphetamine; Amphetamines; Depression; Depressive Disorder; Dextroamphetamine; Humans; Hypertension;

1954
Use of a d-amphetamine-amobarbital combination as an adjunct to the treatment of carcinoma.
    Journal of the American Geriatrics Society, 1954, Volume: 2, Issue:9

    Topics: Amobarbital; Amphetamine; Amphetamines; Anxiety; Barbiturates; Depression; Depressive Disorder; Dext

1954
Perceptual accuracy in schizophrenia, depression, and neurosis, and effects of amytal.
    Journal of abnormal psychology, 1956, Volume: 52, Issue:3

    Topics: Amobarbital; Amphetamine; Amphetamines; Barbiturates; Depression; Depressive Disorder; Humans; Neuro

1956
The treatment of depression with methylamphetamine.
    The Journal of mental science, 1956, Volume: 102, Issue:427

    Topics: Amphetamine; Amphetamines; Depression; Depressive Disorder; Humans; Methamphetamine

1956
Dextro-amphetamine sulfate in mild depression and anxiety.
    International record of medicine and general practice clinics, 1957, Volume: 170, Issue:9

    Topics: Amphetamine; Amphetamines; Anxiety; Anxiety Disorders; Depression; Depressive Disorder; Dextroamphet

1957
Prepartum nausea and vomiting; a new approach to treatment.
    California medicine, 1958, Volume: 88, Issue:2

    Topics: Amphetamine; Depression; Female; Humans; Nausea; Pregnancy; Secologanin Tryptamine Alkaloids; Vomiti

1958
Prepartum depression; a study of seventy unwed mothers treated with d-amphetamine sulfate and amobarbital.
    California medicine, 1958, Volume: 88, Issue:5

    Topics: Amobarbital; Amphetamine; Amphetamines; Anxiety; Apathy; Depression; Depressive Disorder; Dextroamph

1958
Effect of combined chlorpromazine and dextro-amphetamine on severely depressed patients.
    Diseases of the nervous system, 1958, Volume: 19, Issue:6

    Topics: Amphetamine; Amphetamines; Chlorpromazine; Depression; Depressive Disorder; Dextroamphetamine; Human

1958
JB-516 and iproniazid.
    The American journal of psychiatry, 1958, Volume: 115, Issue:6

    Topics: Amphetamine; Amphetamines; Depression; Depressive Disorder; Hydrazines; Iproniazid; Niacin; Nicotini

1958
[Treatment of depressive states].
    Ceskoslovenska psychiatrie, 1959, Volume: 55, Issue:1

    Topics: Amphetamine; Amphetamines; Convulsive Therapy; Depression; Depressive Disorder; Electroconvulsive Th

1959
First-trimester depression: a suggested treatment.
    Obstetrics and gynecology, 1961, Volume: 18

    Topics: Amphetamine; Amphetamines; Depression; Depressive Disorder; Female; Humans; Pregnancy; Pregnancy Tri

1961
Enhancement of amphetamine stimulation and prolongation of barbiturate depression by a substituted pyridl 3,4-blindole derivative.
    The Journal of pharmacology and experimental therapeutics, 1961, Volume: 132

    Topics: Amphetamine; Amphetamines; Analgesia; Anesthesia; Anesthesia and Analgesia; Barbiturates; Depression

1961
A combined psychic and somatic stimulant in the management of industrial fatigue and mild depression.
    International record of medicine, 1959, Volume: 172

    Topics: Amphetamine; Amphetamines; Central Nervous System Stimulants; Depression; Fatigue; Humans; Occupatio

1959
Office care of mild emotional distress.
    Diseases of the nervous system, 1962, Volume: 23

    Topics: Amobarbital; Amphetamine; Amphetamines; Anxiety; Anxiety Disorders; Atropa belladonna; Depression; D

1962
[Preliminary contribution to the application of a psychopharmacological method of differential diagnostic evaluation of depression].
    Rivista sperimentale di freniatria e medicina legale delle alienazioni mentali, 1961, Dec-31, Volume: 85

    Topics: Amphetamine; Amphetamines; Central Nervous System; Depression; Depressive Disorder; Diagnosis, Diffe

1961
Proposal of a psychopharmacological test ("stimulation threshold") for differentiating neurotic from psychotic depressions. Preliminary report.
    Psychopharmacologia, 1962, Volume: 3

    Topics: Amphetamine; Amphetamines; Bipolar Disorder; Depression; Depressive Disorder; Humans; Psychotic Diso

1962
Phenelzine and dexamphetamine in depressive illness. A comparative trial.
    British medical journal, 1962, Jan-06, Volume: 1, Issue:5270

    Topics: Amphetamine; Amphetamines; Depression; Depressive Disorder; Dextroamphetamine; Hydrazines; Phenelzin

1962
Effects and interactions of imipramine, chlorpromazine, reserpine and amphetamine on self-stimulation: possible neurophysiological basis of depression.
    Recent advances in biological psychiatry, 1961, Volume: 4

    Topics: Amphetamine; Amphetamines; Chlorpromazine; Depression; Depressive Disorder; Imipramine; Reserpine; S

1961
A double blind trial of a new preparation for the treatment of mild depression encountered in general practice.
    The British journal of clinical practice, 1963, Volume: 17

    Topics: Amphetamine; Antidepressive Agents; Depression; Depressive Disorder; Double-Blind Method; Family Pra

1963
SUSTAINED-ACTION AMPHETAMINE-MEPROBAMATE COMBINATION FOR THE TREATMENT OF OBESITY.
    Current therapeutic research, clinical and experimental, 1964, Volume: 6

    Topics: Amphetamine; Amphetamines; Appetite Depressants; Biomedical Research; Delayed-Action Preparations; D

1964
EARLY RECOGNITION OF DEPRESSION.
    Geriatrics, 1964, Volume: 19

    Topics: Amitriptyline; Amphetamine; Amphetamines; Barbiturates; Benactyzine; Chlordiazepoxide; Deanol; Depre

1964
ANTAGONISM OF RESERPINE BEHAVIORAL DEPRESSION BY D-AMPHETAMINE.
    The Journal of pharmacology and experimental therapeutics, 1964, Volume: 146

    Topics: Amphetamine; Amphetamines; Animals; Avoidance Learning; Behavior, Animal; Brain Chemistry; Depressio

1964
OTHER ASPECTS OF DEPRESSION.
    Geriatrics, 1965, Volume: 20

    Topics: Alcoholism; Amphetamine; Antidepressive Agents; Barbiturates; Bipolar Disorder; Brain Diseases; Depr

1965
TWO SUICIDE ATTEMPTS WITH CHLORPROMAZINE.
    The American journal of psychiatry, 1965, Volume: 121

    Topics: Amphetamine; Chlorpromazine; Coma; Depression; Dextroamphetamine; Drug Therapy; Gastric Lavage; Hypo

1965
[EFFECT OF METHYLAMPHETAMINE, IPRONIAZID AND TRANYLCYPROMINE ON ADRENALINE PSYCHOMOTOR DEPRESSION].
    Prensa medica argentina, 1964, Dec-25, Volume: 51

    Topics: Amphetamine; Amphetamines; Animals; Depression; Depressive Disorder; Epinephrine; Iproniazid; Metham

1964
TREATMENT OF DEPRESSION.
    Lancet (London, England), 1965, May-01, Volume: 1, Issue:7392

    Topics: Amphetamine; Amphetamines; Antidepressive Agents; Catecholamines; Depression; Depressive Disorder; D

1965
HYPERPYREXIA WITH ANTIDEPRESSANT DRUGS.
    British medical journal, 1965, Jun-26, Volume: 1, Issue:5451

    Topics: Amphetamine; Amphetamines; Antidepressive Agents; Depression; Depressive Disorder; Drug Therapy; Fev

1965
[Abuse of sedatives, with reference to amycal therapy of depression, etc..].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1952, Mar-01, Volume: 72, Issue:5

    Topics: Amphetamine; Amphetamines; Barbiturates; Depression; Depressive Disorder; Humans; Hypnotics and Seda

1952
Psychopathology of schizophrenia and depression. I. Effect of amytal and amphetamine sulfate on level and maintenance of attention.
    The American journal of psychiatry, 1952, Volume: 109, Issue:2

    Topics: Aged; Amobarbital; Amphetamine; Attention; Depression; Depressive Disorder; Humans; Psychopathology;

1952
[Abuse of amphetamine and hypnotics; reply to Tor Christiansen].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1952, Apr-01, Volume: 72, Issue:7

    Topics: Amphetamine; Amphetamines; Depression; Depressive Disorder; Humans; Hypnotics and Sedatives; Mental

1952
The depressed patient; management with the aid of a new medication.
    American practitioner and digest of treatment, 1950, Volume: 1, Issue:8

    Topics: Amphetamine; Amphetamines; Barbital; Depression; Depressive Disorder; Disease Management

1950
PSYCHOTHERAPEUTIC DRUGS IN THE TREATMENT OF DEPRESSIONS.
    Clinical medicine (Northfield, Ill.), 1963, Volume: 70

    Topics: Amitriptyline; Amphetamine; Amphetamines; Antidepressive Agents; Depression; Electroconvulsive Thera

1963
Rats with persistently low or high exploratory activity: behaviour in tests of anxiety and depression, and extracellular levels of dopamine.
    Behavioural brain research, 2007, Feb-27, Volume: 177, Issue:2

    Topics: Amphetamine; Analysis of Variance; Animals; Anxiety; Behavior, Animal; Central Nervous System Stimul

2007
Lesions of dopaminergic neurons in the substantia nigra pars compacta and in the ventral tegmental area enhance depressive-like behavior in rats.
    Behavioural brain research, 2007, Dec-03, Volume: 184, Issue:2

    Topics: Adrenergic Agents; Amphetamine; Analysis of Variance; Animals; Antidepressive Agents; Behavior, Anim

2007
Behavioral characterization of mice deficient in the phosphodiesterase-10A (PDE10A) enzyme on a C57/Bl6N congenic background.
    Neuropharmacology, 2008, Volume: 54, Issue:2

    Topics: Amphetamine; Animals; Anxiety; Avoidance Learning; Behavior, Animal; Biogenic Monoamines; Brain Chem

2008
The use of sodium amytal and benzedrine sulfate in the symptomatic treatment of depressions.
    Diseases of the nervous system, 1949, Volume: 10, Issue:2

    Topics: Amobarbital; Amphetamine; Depression; Depressive Disorder; Sulfates; Sulfur Oxides

1949
Successful treatment of amphetamine addiction in a schizophrenic woman.
    American journal of psychotherapy, 1967, Volume: 21, Issue:2

    Topics: Adult; Amphetamine; Anticonvulsants; Anxiety; Depression; Electroconvulsive Therapy; Female; Humans;

1967
Clinical trial of a new type promptly acting psychoenergetic agent (phenyl-isopropyl-methylpropinyl-HCl, "E-250").
    Acta medica Academiae Scientiarum Hungaricae, 1967, Volume: 23, Issue:3

    Topics: Adult; Amphetamine; Animals; Depression; Dogs; Female; Humans; Male; Middle Aged; Monoamine Oxidase

1967
Rapid desensitization of central beta-receptors and up-regulation of alpha 2-receptors following antidepressant treatment.
    Advances in biochemical psychopharmacology, 1982, Volume: 31

    Topics: Amphetamine; Animals; Antidepressive Agents; Brain; Depression; Drug Synergism; Humans; Male; Rats;

1982
Antidepressants and dopamine autoreceptors: implications for both a novel means of treating depression and understanding bipolar illness.
    Advances in biochemical psychopharmacology, 1982, Volume: 31

    Topics: Amphetamine; Animals; Antidepressive Agents; Bipolar Disorder; Depression; Electrophysiology; Humans

1982
Amphetamine and tranylcypromine in an animal model of depression: pharmacological specificity of the reversal effect.
    Neuroscience and biobehavioral reviews, 1981,Summer, Volume: 5, Issue:2

    Topics: Amphetamine; Animals; Chronic Disease; Corticosterone; Defecation; Depression; Disease Models, Anima

1981
The effect of peripheral inositol injection on rat motor activity models of depression.
    Israel journal of medical sciences, 1993, Volume: 29, Issue:9

    Topics: Amphetamine; Analysis of Variance; Animals; Apomorphine; Depression; Disease Models, Animal; Drug Sy

1993
Rats selectively bred for high and low swim-test activity show differential responses to dopaminergic drugs.
    Psychopharmacology, 1999, Volume: 146, Issue:3

    Topics: Amphetamine; Animals; Apomorphine; Behavior, Animal; Depression; Dopamine; Dopamine Agonists; Dose-R

1999
Amphetamine positive toxicology screen secondary to bupropion.
    Depression and anxiety, 2000, Volume: 12, Issue:1

    Topics: Aged; Amphetamine; Antidepressive Agents, Second-Generation; Bipolar Disorder; Bupropion; Chromatogr

2000
Effects of repeated withdrawal from continuous amphetamine administration on brain reward function in rats.
    Psychopharmacology, 2000, Volume: 152, Issue:4

    Topics: Amphetamine; Amphetamine-Related Disorders; Animals; Brain; Central Nervous System Stimulants; Depre

2000
Fluoxetine combined with a serotonin-1A receptor antagonist reversed reward deficits observed during nicotine and amphetamine withdrawal in rats.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2001, Volume: 25, Issue:1

    Topics: Aminopyridines; Amphetamine; Amphetamine-Related Disorders; Animals; Body Weight; Brain; Depression;

2001
The pharmacologic treatment of depression.
    American journal of psychotherapy, 1979, Volume: 33, Issue:1

    Topics: Amphetamine; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Deanol; De

1979
A reward-reduction model of depression using self stimulating rats: an appraisal.
    Pharmacology, biochemistry, and behavior, 1979, Volume: 10, Issue:3

    Topics: Amphetamine; Animals; Depression; Disease Models, Animal; Humans; Imipramine; Male; Protriptyline; R

1979
Non-random relation between drugs of abuse and psychiatric diagnosis.
    Journal of psychiatric research, 1977, Volume: 13, Issue:3

    Topics: Adult; Alcoholism; Amphetamine; Barbiturates; Depression; Hallucinogens; Heroin; Humans; Male; Menta

1977
Psychosocial dysfunctions as precursors to amphetamine abuse among adolescents.
    Addictive diseases, 1976, Volume: 2, Issue:3

    Topics: Adolescent; Adult; Amphetamine; Antisocial Personality Disorder; Depression; Female; Humans; Male; M

1976
Reduced growth hormone responses to amphetamine in "endogenous" depressive patients: studies in normal, "reactive" and "endogenous" depressive, schizophrenic, and chronic alcoholic subjects.
    Archives of general psychiatry, 1976, Volume: 33, Issue:12

    Topics: Adjustment Disorders; Adult; Aged; Alcoholism; Amphetamine; Blood Pressure; Chronic Disease; Depress

1976
Gradients of biogenic amine metabolites in cerebrospinal fluid.
    Diseases of the nervous system, 1975, Volume: 36, Issue:1

    Topics: Alzheimer Disease; Amphetamine; Brain Diseases; Brain Neoplasms; Depression; Homovanillic Acid; Huma

1975
Problems and treatment of drug abuse in adolescence.
    Proceedings of the Royal Society of Medicine, 1975, Volume: 68, Issue:9

    Topics: Adolescent; Amphetamine; Cannabis; Depression; Family Characteristics; Female; Guilt; Humans; Identi

1975
Synthesis and pharmacological evaluation of some phenothiazines as antidepressants.
    Arzneimittel-Forschung, 1992, Volume: 42, Issue:3

    Topics: Amphetamine; Animals; Antidepressive Agents; Depression; Drug Synergism; Female; Male; Mice; Nervous

1992
Brain laterality as a determinant of susceptibility to depression in an animal model.
    Brain research, 1991, Jun-07, Volume: 550, Issue:2

    Topics: Amphetamine; Analysis of Variance; Animals; Brain; Depression; Disease Models, Animal; Escape Reacti

1991
Psychological change during residence in a rehabilitation centre for female drug misusers. Part I. Drug misusers.
    Drug and alcohol dependence, 1991, Volume: 27, Issue:2

    Topics: Adolescent; Adult; Amphetamine; Anxiety; Depression; Female; Heroin Dependence; Humans; Opioid-Relat

1991
Lack of tolerance to imipramine or mianserine in two animal models of depression.
    Pharmacology, 1990, Volume: 41, Issue:6

    Topics: Amphetamine; Animals; Anorexia; Behavior, Animal; Depression; Disease Models, Animal; Dose-Response

1990
Cerebral correlates of depressed behavior in rats, visualized using 14C-2-deoxyglucose autoradiography.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1988, Volume: 8, Issue:6

    Topics: alpha-Methyltyrosine; Amphetamine; Animals; Autoradiography; Behavior, Animal; Brain; Carbon Radiois

1988
[Effect of psychotropic substances on the development of alcoholic motivation in noninbred white rats].
    Biulleten' eksperimental'noi biologii i meditsiny, 1986, Volume: 101, Issue:3

    Topics: Adaptation, Psychological; Alcohol Drinking; Amitriptyline; Amphetamine; Animals; Anti-Anxiety Agent

1986
Amphetamine withdrawal: depression and M.H.P.G. excretion.
    Lancet (London, England), 1971, Aug-28, Volume: 2, Issue:7722

    Topics: Amphetamine; Animals; Brain; Catechols; Depression; Glycols; Humans; Norepinephrine; Substance Withd

1971
Psychiatric problems of the aged.
    Journal of the American Geriatrics Society, 1974, Volume: 22, Issue:8

    Topics: Adjustment Disorders; Aged; Amphetamine; Antidepressive Agents; Antipsychotic Agents; Attitude of He

1974
The psychiatrist attitudes and therapeutic means when faced with resistant depressions.
    Pharmakopsychiatrie, Neuro-Psychopharmakologie, 1974, Volume: 7, Issue:4

    Topics: Amitriptyline; Amphetamine; Antidepressive Agents; Autistic Disorder; Depression; Drug Resistance; D

1974
Clinical application of antidepressant agents in disabled and rehabilitation patients.
    Archives of physical medicine and rehabilitation, 1965, Volume: 46, Issue:11

    Topics: Aged; Amitriptyline; Amphetamine; Antidepressive Agents; Depression; Disabled Persons; Hemiplegia; H

1965
Amphetamine withdrawal: affective state, sleep patterns, and MHPG excretion.
    The American journal of psychiatry, 1972, Volume: 129, Issue:3

    Topics: Adult; Affect; Amphetamine; Brain; Catechols; Depression; Electroencephalography; Female; Glycols; H

1972
On the treatment of rapid eye movement narcolepsy.
    Archives of neurology, 1974, Volume: 30, Issue:1

    Topics: Adult; Amphetamine; Antidepressive Agents; Cataplexy; Depression; Desipramine; Electroencephalograph

1974
Pharmacologic studies with 7-benzyl-1-ethyl-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid.
    The Journal of pharmacology and experimental therapeutics, 1967, Volume: 158, Issue:2

    Topics: Amphetamine; Animals; Catecholamines; Chlorine; Depression; Drug Antagonism; Drug Synergism; Humans;

1967
Pharmacological actions of 1-(o-methoxyphenoxy)3-isopropylamino-2-propanol hydrochloride (S-D-1601), a new beta-blocking agent.
    Arzneimittel-Forschung, 1970, Volume: 20, Issue:8

    Topics: Adrenergic beta-Antagonists; Amphetamine; Anesthetics, Local; Animals; Anti-Arrhythmia Agents; Antic

1970
Pharmacological and dynamic factors in psychotropic drug therapy.
    American journal of psychoanalysis, 1970, Volume: 30, Issue:2

    Topics: Adult; Amphetamine; Antidepressive Agents; Antitubercular Agents; Anxiety; Bipolar Disorder; Chlorpr

1970
Clinical and pharmacological investigation of a new psychotropic drug sulpiride (Dogmatil).
    Activitas nervosa superior, 1971, Volume: 13, Issue:3

    Topics: Adult; Amides; Amphetamine; Animals; Body Temperature; Central Nervous System Stimulants; Chlorproma

1971
Personality characteristics of adolescent users of dangerous drugs as indicated by the Minnesota Multiphasic Personality Inventory.
    The Journal of nervous and mental disease, 1972, Volume: 154, Issue:4

    Topics: Adolescent; Adolescent Psychiatry; Adult; Amphetamine; Barbiturates; Cannabis; Depression; Female; H

1972
Personality attributes of the young, nonaddicted drug abuser.
    The International journal of the addictions, 1972, Volume: 7, Issue:1

    Topics: Adolescent; Adult; Age Factors; Amphetamine; Antisocial Personality Disorder; Anxiety; Barbiturates;

1972
Personality characteristics and drug of choice.
    The International journal of the addictions, 1972, Volume: 7, Issue:1

    Topics: Amphetamine; Analysis of Variance; Anxiety; Barbiturates; Depression; Diagnosis, Differential; Femal

1972
Drugs that cause depression.
    The Medical letter on drugs and therapeutics, 1972, May-12, Volume: 14, Issue:10

    Topics: Amphetamine; Antipsychotic Agents; Brain; Contraceptives, Oral; Depression; Drug-Related Side Effect

1972
The combined abuse of alcohol and amphetamines.
    The American journal of psychiatry, 1974, Volume: 131, Issue:11

    Topics: Adult; Alcohol Drinking; Alcoholism; Amphetamine; Anxiety; Depression; Drug Interactions; Employment

1974
Biochemical criteria for classifying depressive disorders and predicting responses to pharmacotherapy: preliminary findings from studies of norepinephrine metabolism. Contributions to biochemistry.
    Pharmakopsychiatrie, Neuro-Psychopharmakologie, 1974, Volume: 7, Issue:2

    Topics: Adolescent; Adult; Aged; Amitriptyline; Amphetamine; Anxiety; Bipolar Disorder; Brain; Depression; F

1974
Some descriptive measures on 100 consecutive VA hospital drug abuse admissions.
    The International journal of the addictions, 1974, Volume: 9, Issue:3

    Topics: Adolescent; Adult; Amphetamine; Antisocial Personality Disorder; Anxiety; Barbiturates; Depression;

1974
Amphetamine psychosis: behavioral and biochemical aspects.
    Journal of psychiatric research, 1974, Volume: 11

    Topics: Adolescent; Adult; Affect; Alcoholism; Amphetamine; Brain; Cognition Disorders; Delusions; Depressio

1974
Biogenic amines and their impact in psychiatry.
    Seminars in psychiatry, 1972, Volume: 4, Issue:3

    Topics: Amphetamine; Biogenic Amines; Brain; Depression; Ephedrine; Epinephrine; Humans; Imipramine; Mental

1972
[Personality aspects of drug abuse by 19-year-old males (author's transl)].
    Archiv fur Psychiatrie und Nervenkrankheiten, 1973, Jul-20, Volume: 217, Issue:3

    Topics: Adult; Affective Symptoms; Amphetamine; Anxiety; Cannabis; Character; Depression; Hallucinogens; Hum

1973
Treatment of compulsive eating disturbances with anticonvulsant medication.
    The American journal of psychiatry, 1974, Volume: 131, Issue:4

    Topics: Adolescent; Adult; Amphetamine; Anorexia Nervosa; Body Image; Body Weight; Compulsive Behavior; Depr

1974
Letter: Pathophysiology of depressive syndromes.
    Biological psychiatry, 1974, Volume: 8, Issue:1

    Topics: Amphetamine; Depression; Dextroamphetamine; Humans; Monoamine Oxidase Inhibitors; Phenethylamines; S

1974
Motives for drug use among light and heavy users.
    The Journal of nervous and mental disease, 1974, Volume: 159, Issue:2

    Topics: Adult; Amphetamine; Anxiety; Barbiturates; Cannabis; Cocaine; Creativity; Depression; Exploratory Be

1974
Clinical perspectives on antidepressant therapy.
    The American journal of psychiatry, 1968, Volume: 124, Issue:11

    Topics: Adult; Amphetamine; Antidepressive Agents; Depression; Diagnosis, Differential; Electroconvulsive Th

1968
Amphetamine and other non-opioid drug users attending a special drug dependence clinic.
    British medical journal, 1972, May-06, Volume: 2, Issue:5809

    Topics: Adolescent; Adult; Age Factors; Amphetamine; Barbiturates; Chloroform; Depression; Drug and Narcotic

1972
EEG and behavioral effects in animals of some amphetamine derivatives with hallucinogenic properties.
    Behavioral biology, 1972, Volume: 7, Issue:3

    Topics: Alkaloids; Allyl Compounds; Amino Alcohols; Amphetamine; Animals; Anisoles; Behavior, Animal; Brain;

1972
[Amphetamine poisoning].
    Lakartidningen, 1972, Sep-20, Volume: 69, Issue:39

    Topics: Adolescent; Adult; Amphetamine; Blood Pressure; Depression; Euphoria; Female; Humans; Male; Mental D

1972
A clinical view of the amphetamines.
    American family physician, 1971, Volume: 4, Issue:5

    Topics: Amphetamine; Appetite Depressants; Central Nervous System Diseases; Depression; Diazepam; Hospitaliz

1971
Possible involvement of glycogen phosphorylase of brain in the affective states.
    International pharmacopsychiatry, 1971, Volume: 6, Issue:2

    Topics: Amphetamine; Animals; Antidepressive Agents; Brain; Chlorpromazine; Depression; Desipramine; Drug In

1971
[The pharmacologic properties and therapeutic effectiveness of the new antidepressant preparation Azaphen].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1969, Volume: 69, Issue:8

    Topics: Adult; Aged; Amphetamine; Animals; Antidepressive Agents; Bipolar Disorder; Cats; Depression; Depres

1969
Coping on amphetamines.
    The New England journal of medicine, 1970, Feb-05, Volume: 282, Issue:6

    Topics: Amphetamine; Antidepressive Agents; Depression; Fatigue; Humans

1970
The drug treatment of depression.
    JAMA, 1970, Feb-16, Volume: 211, Issue:7

    Topics: Amphetamine; Depression; Humans

1970
Drugs in the management of depression.
    Northwest medicine, 1970, Volume: 69, Issue:10

    Topics: Amphetamine; Antidepressive Agents; Barbiturates; Depression; Humans; Tranquilizing Agents

1970
Amphetamines, barbiturates, LSD and cannabis: their use and misuse.
    Reports on public health and medical subjects, 1970, Volume: 124

    Topics: Amphetamine; Barbiturates; Cannabis; Child Behavior Disorders; Crime; Depression; Humans; Hyperkines

1970
Amphetamines: a dangerous illusion.
    Annals of internal medicine, 1971, Volume: 74, Issue:4

    Topics: Amphetamine; Autonomic Nervous System; Cardiovascular System; Depression; Drug Prescriptions; Humans

1971
[Mechanisms of short-term memory].
    Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova, 1971, Volume: 21, Issue:2

    Topics: Amobarbital; Amphetamine; Chlorpromazine; Depression; Humans; Hypothalamus; Imipramine; Memory, Shor

1971
A comparative study of the therapeutic effects of sone 4-chlorinated amphetamine derivatives in depressive patients.
    Psychopharmacologia, 1971, Volume: 20, Issue:1

    Topics: Adult; Aged; Amphetamine; Animals; Antidepressive Agents; Chlorine; Depression; Female; Humans; Male

1971
Psychopharmacological approach to psychosomatic medicine. Experimental and clinical research.
    Acta neurologica latinoamericana, 1967, Volume: 13, Issue:1

    Topics: Amitriptyline; Amphetamine; Animals; Anxiety Disorders; Benactyzine; Depression; Guinea Pigs; Hostil

1967
Treatment of depression.
    British medical journal, 1968, Apr-20, Volume: 2, Issue:5598

    Topics: Amphetamine; Depression; Electroconvulsive Therapy; Humans; Monoamine Oxidase Inhibitors

1968
Use of amphetamines.
    British medical journal, 1968, May-04, Volume: 2, Issue:5600

    Topics: Amphetamine; Depression; Humans

1968
Effect of imipramine, physostigmine and amphetamine on the electrical activity of the brain in the cat.
    Psychopharmacologia, 1968, Volume: 13, Issue:2

    Topics: Amphetamine; Amygdala; Animals; Arousal; Cats; Cerebral Cortex; Cerebral Ventricles; Depression; Ele

1968
Characteristics of drug abusers admitted to a psychiatric hospital.
    JAMA, 1968, Jul-15, Volume: 205, Issue:3

    Topics: Adult; Age Factors; Amphetamine; Antisocial Personality Disorder; Antitussive Agents; Barbiturates;

1968
Control of amphetamine preparations.
    British medical journal, 1968, Nov-30, Volume: 4, Issue:5630

    Topics: Amphetamine; Depression; Diethylpropion; Drug and Narcotic Control; Humans; Obesity; Phenmetrazine;

1968
[Study on the effects of amphetamine on human personality].
    Psychopharmacologia, 1968, Volume: 12, Issue:3

    Topics: Adult; Amphetamine; Depression; Humans; Learning; Male; Mental Processes; Perception; Personality; P

1968
[Subjective effects of amphetamine on man as a function of personality].
    Psychopharmacologia, 1968, Volume: 12, Issue:3

    Topics: Adult; Amphetamine; Blood Pressure; Depression; Humans; Learning; Male; Perception; Personality

1968
On the central action of some oxoindole compounds.
    Archivum immunologiae et therapiae experimentalis, 1969, Volume: 17, Issue:1

    Topics: Absorption; Amphetamine; Animals; Blood Pressure; Central Nervous System; Depression; Drug Antagonis

1969
Antidepressive drugs.
    Canadian Medical Association journal, 1965, Nov-20, Volume: 93, Issue:21

    Topics: Adolescent; Adult; Aged; Amitriptyline; Amphetamine; Antidepressive Agents; Classification; Depressi

1965
Drugs for depression.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1966, Feb-26, Volume: 40, Issue:9

    Topics: Amitriptyline; Amphetamine; Depression; Electroconvulsive Therapy; Humans; Imipramine; Monoamine Oxi

1966
Psychiatric complications of amphetamine substances.
    Acta psychiatrica Scandinavica, 1966, Volume: 42, Issue:3

    Topics: Adolescent; Adult; Amitriptyline; Amphetamine; Chlordiazepoxide; Depression; Ephedrine; Female; Hall

1966