baicalin has been researched along with Depression in 20 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 10 (50.00) | 24.3611 |
| 2020's | 10 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fujita, Y; Hashimoto, K; Iwata, M; Oda, Y; Shirayama, Y | 1 |
| Cheng, Y; Lu, Y; Pei, L; Sun, G; Wang, Z | 1 |
| Bai, M; Jin, X; Li, C; Li, Y; Lu, S; Shen, J; Xu, E; Zhu, L | 1 |
| Cheng, YT; Lu, Y; Pei, L; Sun, GQ; Wang, Z | 1 |
| Feng, D; Ma, Z; Rui, W; Wang, Z | 1 |
| Li, X; Liu, A; Liu, Q; Liu, Y; Ma, J; Yang, Z | 1 |
| Fang, A; Li, Y; Wu, B; Wu, X; Zhang, Y | 1 |
| Deng, X; Fu, Q; Fu, X; Jiao, J; Ma, S; Ma, Z; Qin, T; Yu, J | 1 |
| Cao, Z; Du, Y; Jia, Z; Lu, Y; Pei, L; Sun, G; Xiao, Z; Yang, J | 1 |
| Cao, Z; Chen, Y; Chu, L; Jia, Z; Lu, Y; Pei, L; Yang, J; Zhang, J; Zhang, S; Zhao, J | 1 |
| Liu, C; Liu, X | 1 |
| Deng, R; Du, Q; Gao, C; Li, W; Shen, J; Wang, Q; Xu, A | 1 |
| Deng, XY; Fu, Q; Li, YQ; Ma, SP; Ma, ZQ; Qu, R; Shang, ZY; Zeng, MJ; Zhang, CY; Zhao, F; Zhou, LP | 1 |
| Dong, Y; Li, L; Liu, L; Shan, X; Wang, H; Xia, B | 1 |
| Deng, X; Li, Y; Liu, D; Liu, K; Ma, S; Ma, Z; Qu, R; Xu, L; Zhang, R | 1 |
| Deng, XY; Guo, LT; Ji, ZY; Ma, SP; Ma, ZQ; Su, J; Wang, SQ; Xu, LX; Zhang, RY; Zhao, QW | 1 |
| Chu, L; Guan, Z; Liu, Y; Lu, Y; Pei, L; Sun, G; Yang, F; Zhang, Z; Zhao, J | 1 |
| Ma, SP; Qu, R; Yang, SJ; Yin, ZJ; Yu, HY | 1 |
| Dong, Y; Ma, J; Pan, X; Su, G; Wang, F; Wu, C; Yang, J; Zhang, K | 1 |
| Jiao, S; Li, J; Li, YC; Shen, JD; Wang, R; Yi, LT | 1 |
20 other study(ies) available for baicalin and Depression
| Article | Year |
|---|---|
The Toll-like receptor 4 antagonist TAK-242 induces antidepressant-like effects in a rat learned helplessness model of depression through BDNF-TrkB signaling and AMPA receptor activation.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Brain-Derived Neurotrophic Factor; Depression; Disease Models, Animal; Flavonoids; Helplessness, Learned; Male; Rats; Rats, Sprague-Dawley; Receptor, trkB; Receptors, AMPA; Signal Transduction; Sulfonamides; Toll-Like Receptor 4 | 2022 |
Baicalin Coadministration with Lithium Chloride Enhanced Neurogenesis via GSK3β Pathway in Corticosterone Induced PC-12 Cells.
Topics: Antidepressive Agents; Brain-Derived Neurotrophic Factor; Corticosterone; Depression; Flavonoids; Glycogen Synthase Kinase 3 beta; Hippocampus; Lithium Chloride; Neurogenesis | 2022 |
Baicalin ameliorates CUMS-induced depression-like behaviors through activating AMPK/PGC-1α pathway and enhancing NIX-mediated mitophagy in mice.
Topics: AMP-Activated Protein Kinases; Animals; Depression; Membrane Proteins; Mice; Mitochondrial Proteins; Mitophagy; Molecular Docking Simulation; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha | 2023 |
Baicalin Ameliorates Corticosterone-Induced Depression by Promoting Neurodevelopment of Hippocampal via mTOR/GSK3β Pathway.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Corticosterone; Depression; Disease Models, Animal; Fluoxetine; Glycogen Synthase Kinase 3 beta; Hippocampus; Male; Mammals; Mice; Reproducibility of Results; RNA, Messenger; TOR Serine-Threonine Kinases | 2023 |
Baicalin attenuates chronic unpredictable mild stress-induced hippocampal neuronal apoptosis through regulating SIRT1/PARP1 signaling pathway.
Topics: Animals; Antidepressive Agents; Apoptosis; Depression; Disease Models, Animal; Flavonoids; Hippocampus; Mice; Neurons; Poly (ADP-Ribose) Polymerase-1; Signal Transduction; Sirtuin 1; Stress, Psychological | 2023 |
Widely targeted metabolomics unveils baicalin-induced hippocampal metabolic alternations in a rat model of chronic unpredictable mild stress.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Depression; Disease Models, Animal; Hippocampus; Metabolomics; Mice; Rats; Stress, Psychological; Sucrose | 2024 |
Baicalin attenuates inflammatory pain associated depressive symptoms via Akt-mediated adult hippocampal neurogenesis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Depression; Flavonoids; Hippocampus; Hyperalgesia; Inflammation; Male; Mice; Neural Stem Cells; Neurogenesis; Pain Measurement; Proto-Oncogene Proteins c-akt; Signal Transduction | 2020 |
A New Perspective on Ameliorating Depression-Like Behaviors: Suppressing Neuroinflammation by Upregulating PGC-1α.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Line, Tumor; Depression; Dose-Response Relationship, Drug; Flavonoids; Hindlimb Suspension; Hippocampus; Humans; Inflammation; Inflammation Mediators; Male; Mice; Mice, Inbred ICR; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Up-Regulation | 2021 |
Baicalin promotes hippocampal neurogenesis via the Wnt/β-catenin pathway in a chronic unpredictable mild stress-induced mouse model of depression.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents; Depression; Doublecortin Protein; Flavonoids; Hippocampus; Male; Mice; Mice, Inbred ICR; Neurogenesis; Stress, Psychological; Wnt Signaling Pathway | 2021 |
Baicalin ameliorates chronic unpredictable mild stress-induced depression through the BDNF/ERK/CREB signaling pathway.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Brain-Derived Neurotrophic Factor; Cognitive Dysfunction; Cyclic AMP Response Element-Binding Protein; Depression; Disease Models, Animal; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Fluoxetine; Male; MAP Kinase Signaling System; Mice; Mice, Inbred ICR; Neuroprotective Agents; Random Allocation; Signal Transduction; Stress, Psychological | 2021 |
Baicalin ameliorates chronic unpredictable mild stress-induced depressive behavior: Involving the inhibition of NLRP3 inflammasome activation in rat prefrontal cortex.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Depression; Flavonoids; Inflammasomes; Interleukin-1beta; Interleukin-6; Locomotion; Male; NLR Family, Pyrin Domain-Containing 3 Protein; Prefrontal Cortex; Rats, Sprague-Dawley; Stress, Psychological | 2017 |
Baicalin Modulates APPL2/Glucocorticoid Receptor Signaling Cascade, Promotes Neurogenesis, and Attenuates Emotional and Olfactory Dysfunctions in Chronic Corticosterone-Induced Depression.
Topics: Adaptor Proteins, Signal Transducing; Animals; Anxiety; Behavior, Animal; Brain; Cell Line, Tumor; Corticosterone; Depression; Disease Models, Animal; Emotions; Flavonoids; Humans; Male; Mice, Inbred C57BL; Mice, Transgenic; Neurogenesis; Olfactory Bulb; Receptors, Glucocorticoid; Signal Transduction | 2018 |
Baicalin exerts neuroprotective effects via inhibiting activation of GSK3β/NF-κB/NLRP3 signal pathway in a rat model of depression.
Topics: Animals; Apoptosis; Depression; Doublecortin Protein; Flavonoids; Glycogen Synthase Kinase 3 beta; Hippocampus; Male; Motor Activity; Neuroprotective Agents; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Rats; Rats, Sprague-Dawley; Signal Transduction; Stress, Psychological | 2018 |
Anti-Depressive Effectiveness of Baicalin In Vitro and In Vivo.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Cell Survival; Chronic Disease; Cytokines; Depression; Disease Models, Animal; Flavonoids; Hindlimb Suspension; HMGB1 Protein; Inflammation Mediators; Mice, Inbred ICR; NF-kappa B; PC12 Cells; Rats; Signal Transduction; Stress, Psychological; Swimming; Toll-Like Receptor 4 | 2019 |
Baicalin exerts antidepressant effects through Akt/FOXG1 pathway promoting neuronal differentiation and survival.
Topics: Animals; Antidepressive Agents; Cell Differentiation; Depression; Disease Models, Animal; Doublecortin Protein; Fibroblast Growth Factor 2; Flavonoids; Forkhead Transcription Factors; Hippocampus; Male; Medicine, Chinese Traditional; Mice; Mice, Inbred ICR; Nerve Tissue Proteins; Neurogenesis; Neurons; Proto-Oncogene Proteins c-akt; Signal Transduction; Stress, Psychological | 2019 |
Baicalin ameliorates neuroinflammation-induced depressive-like behavior through inhibition of toll-like receptor 4 expression via the PI3K/AKT/FoxO1 pathway.
Topics: Animals; Anti-Inflammatory Agents; Depression; Flavonoids; Forkhead Box Protein O1; Inflammation; Male; Mice; Mice, Inbred ICR; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Psychological Distress; Signal Transduction; Toll-Like Receptor 4 | 2019 |
Baicalin regulates depression behavior in mice exposed to chronic mild stress via the Rac/LIMK/cofilin pathway.
Topics: Actin Depolymerizing Factors; Animals; Behavior, Animal; Brain-Derived Neurotrophic Factor; Chronic Disease; Depression; Disks Large Homolog 4 Protein; Flavonoids; Hippocampus; Lim Kinases; Male; Mice; Neurons; rac GTP-Binding Proteins; Receptor, trkB; RNA, Messenger; Signal Transduction; Stress, Psychological; Swimming; Synaptophysin | 2019 |
Baicalin Reverses Depressive-Like Behaviours and Regulates Apoptotic Signalling Induced by Olfactory Bulbectomy.
Topics: Animals; Antidepressive Agents; Apoptosis; Apoptotic Protease-Activating Factor 1; Behavior, Animal; Caspases; Depression; Depressive Disorder, Major; Flavonoids; Glutathione Peroxidase; Hippocampus; Male; Malondialdehyde; Olfactory Bulb; Oxidative Stress; Phytotherapy; Plant Extracts; Rats, Wistar; Scutellaria; Signal Transduction; Superoxide Dismutase; Synaptophysin | 2016 |
Baicalin promotes hippocampal neurogenesis via SGK1- and FKBP5-mediated glucocorticoid receptor phosphorylation in a neuroendocrine mouse model of anxiety/depression.
Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Anxiety; Behavior, Animal; Corticosterone; Depression; Disease Models, Animal; Doublecortin Protein; Flavonoids; Hippocampus; Immediate-Early Proteins; Male; Mice; Mice, Inbred C57BL; Neurogenesis; Neurosecretory Systems; Phosphorylation; Protein Serine-Threonine Kinases; Receptors, Glucocorticoid; Tacrolimus Binding Proteins | 2016 |
Chronic treatment with baicalin prevents the chronic mild stress-induced depressive-like behavior: involving the inhibition of cyclooxygenase-2 in rat brain.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Brain; Corticosterone; Cyclooxygenase 2 Inhibitors; Depression; Depressive Disorder; Dinoprostone; Flavonoids; Hindlimb Suspension; Male; Rats; Rats, Wistar; Stress, Psychological; Swimming | 2013 |