homocysteine and Depression

homocysteine has been researched along with Depression in 82 studies

Research

Studies (82)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	3 (3.66)	18.2507
2000's	30 (36.59)	29.6817
2010's	40 (48.78)	24.3611
2020's	9 (10.98)	2.80

Authors

Authors	Studies
Chen, Y; Peng, M; Zou, H	1
Kong, X; Ma, J; Meng, D; Wei, Y; Xu, Y; Zhang, Z	1
Andrieu, S; Araujo de Carvalho, I; Beard, J; de Souto Barreto, P; Giudici, KV; Guerville, F; Rolland, Y; Vellas, B	1
Bhosle, J; Gunapala, R; Hodgkiss, A; Kumar, R; Mak, D; Minchom, A; O'Brien, MER; Popat, S; Walder, D; Yousaf, N	1
Li, H; Li, J; Li, S; Shao, S; Tian, Y; Wang, S; Yao, D; Zhang, H; Zhang, S; Zhu, Z	1
Cong, Y; Liu, H; Zhou, Y	1
Amini, M; Hosseinzadeh, M; Khosravi, M; Mansoori, A; Raisi, F; Sotoudeh, G	1
Fan, W; Tang, W; Wang, W; Zhang, C; Zhang, Y; Zhao, J	1
Chen, B; Chen, X; Dai, C; Huang, X; Liang, W; Mai, N; Ning, Y; Ouyang, C; Peng, Q; Wu, Z; Zhang, M; Zhang, W; Zhong, X; Zhou, H	1
Armin, M; Askari, G; Clark, CCT; Lotfi, K; Moradi, F; Rouhani, MH	1
Castro, F; Chavez, CA; de Erausquin, GA; Lee, JH; Maestre, GE; Melgarejo, J; Terwilliger, JD	1
Cheng, LS; Ji, K; Shen, Y; Tu, WJ; Zhang, LJ	1
Chen, YH; Chiou, HY; Chung, KH	1
Bu, X; Chen, CS; Chen, J; Cui, Y; Guo, L; He, J; Ju, Z; Li, D; Wang, X; Xu, T; Yin, J; Zhang, J; Zhang, Y; Zhong, C; Zhu, Z	1
Awwad, HM; Eskelund, AR; Geisel, J; Obeid, R; Tillmann, S; Treccani, G; Wegener, G	1
Brandmayr, W; Enko, D; Halwachs-Baumann, G; Kriegshäuser, G; Meinitzer, A; Schnedl, WJ	1
Casey, MC; Cunningham, C; Hoey, L; Hughes, CF; Laird, E; McCarroll, K; McNulty, H; Molloy, AM; Moore, K; O'Kane, M; Strain, JJ; Tracey, F; Ward, M	1
An, SC; Liu, H; Qiao, H; Wen, LM	1
Humphries, D; Rechenberg, K	1
de la Iglesia, R; Lahortiga, F; Lopez-Legarrea, P; Martinez, JA; Perez-Cornago, A; Zulet, MA	1
Chengfeng, S; Lei, W; Lingjia, Q; Rui, Z; Wei, L; Xinxing, W	1
Agrawal, A; Dubey, GP; Ilango, K; Karmakar, D; Kumari, R; Singh, GP; Singh, PK	1
Li, WG; Shi, JP; Tang, CZ; Wang, WS; Zhang, YL	1
Assies, J; de Vries, GJ; Lok, A; Mocking, R; Olff, M; Schene, A	1
Bhatia, P; Singh, N	1
Cox, KH; Peters, R; Pipingas, A; Scholey, AB; White, DJ	1
Kim, SY; Lee, HK; Sok, SR	1
Karas Kuželički, N	1
Ahn, Y; Bae, KY; Hong, YJ; Jeong, MH; Kang, H; Kang, HJ; Kim, JM; Kim, SW; Moon, WJ; Shin, IS; Stewart, R; Yoon, JS	1
Brouwer, IA; Elstgeest, LE; Penninx, BW; van Schoor, NM; Visser, M	1
Cao, LL; Li, Y; Liu, L; Qi, QD	1
Gustafson, L; Hultberg, B; Nilsson, K	1
Miller, AL	1
Belén Sánchez-Saudinós, M; Blanco-Vaca, F; Blesa, R; Clarimón, J; Gich, I; Gómez-Isla, T; Lázaro, E; Lleó, A; Molina-Porcel, L; Sala, I	1
Colla, M; Endres, M; Kronenberg, G	1
Chellappa, P; Ramaraj, R	1
Bescos, E; Clavero, P; García-Garcia, D; Irigoien, J; Irurzun, C; Kulisevsky, J; Lage, PM; Lamet, I; Matsubara, JM; Obeso, JA; Pagonabarraga, J; Pérez-Tur, J; Rodriguez-Oroz, MC; Samaranch, L; Sanchez-Mut, J; Toledo, JB	1
Feng, L; Kua, EH; Ng, TP; Niti, M; Yap, KB	1
Matsushita, Y; Mishima, N; Mizoue, T; Nanri, A; Ohta, M; Sasaki, S; Sato, M	1
Alexopoulos, P; Bleich, S; Herpertz, SC; Irmisch, G; Jung, SU; Kurz, A; Perneczky, R; Poppe, K; Prehn, K; Sebb, H; Topalidis, S	1
Almeida, OP; Fenner, S; Flicker, L; Ford, AH; Hegarty, S; Hirani, V; McCaul, K; van Bockxmeer, F	1
Sui, R; Zhang, L	1
Beydoun, HA; Beydoun, MA; Shroff, MR; Zonderman, AB	1
Choi, KC; Kwok, T; Lam, LC; Law, CB; Lee, J; Pan, PC; Yung, CY	1
Hayashi, A; Hirowatari, T; Hirowatari, Y; Ohsawa, M; Suganuma, N; Watanabe, H	1
Crott, JW; Lai, CQ; Ordovas, JM; Troen, AM; Tucker, KL; Ye, X	1
Gariballa, S	1
Mijajlovic, M; Novakovic, I; Obrenovic, R; Pavlovic, AM; Pekmezovic, T; Sternic, N; Tomic, G	1
D'Anci, KE; Dallal, GE; Dobson, B; Jacques, PF; Levey, AS; Moorthy, D; Rogers, G; Rosenberg, IH; Scott, TM; Selhub, J; Troen, AM; Weiner, DE	1
Brown, ES; DeFina, LF; Gu, P; John, S; Leonard, D; Weiner, MF	1
Awara, MA; Elnenaei, MO; Zahid, S	1
Brodaty, H; Crawford, J; Draper, B; Kang, K; Kochan, NA; Lipnicki, DM; Lux, O; Mather, KA; Reppermund, S; Sachdev, PS; Slavin, MJ; Trollor, JN	1
Crott, JW; Griffith, J; Lai, CQ; Moorthy, D; Ordovás, JM; Parnell, LD; Peter, I; Rosenberg, IH; Scott, TM; Selhub, J; Troen, AM; Tucker, KL	1
Alfonso, H; Almeida, OP; Flicker, L; Hankey, GJ; McCaul, K; Yeap, BB	1
Chen, R; Liu, Y; Qin, L; Tang, Y; Zhang, R	1
Drevon, CA; Engedal, K; Nurk, E; Nygaard, HA; Refsum, H; Smith, AD; Tell, GS; Ueland, PM; Vogiatzoglou, A; Vollset, SE	1
Peskin, ER; Pfeiffer, EA; Porsteinsson, AP; Schneider, LS	1
Kamolz, S; Pfuhlmann, B; Reif, A; Schneider, MF	1
Almeida, OP; Flicker, L; Gelavis, A; Lautenschlager, N; Leedman, P; Ludlow, J; Vasikaran, S	1
Abeling, NG; Assies, J; Bockting, CL; Duran, M; Lieverse, R; Lok, A; Schene, AH; Visser, I; Weverling, GJ	1
Acres, J; Almeida, OP; Flicker, L; Jamrozik, K; Martins, RN; Norman, P; Taddei, K; Thomas, J	1
Bottiglieri, T; Dewey, RB; Diaz-Arrastia, R; Hernandez, C; Lacritz, L; O'Suilleabhain, PE; Sung, V	1
Calabrese, PA; Cossi, S; De Martinis, M; Grassi, V; Marengoni, A; Orini, S	1
Allen, LH; Green, R; Haan, MN; Miller, JW; Ramos, MI	1
Almeida, OP; Flicker, L; Lautenschlager, NT; Leedman, P; van Bockxmeer, FM; Vasikaran, S	1
Alfthan, G; Hintikka, J; Kaplan, GA; Nyyssönen, K; Ruusunen, A; Salonen, JT; Tolmunen, T; Viinamäki, H; Voutilainen, S	1
Almeida, OP; Flicker, L; Lautenschlager, NT; Leedman, P; Vasikaran, S	1
Bottiglieri, T	1
Bjelland, I; Gjesdal, CG; Nurk, E; Nygård, O; Refsum, H; Smith, AD; Tell, GS; Tverdal, A; Ueland, PM; Vollset, SE	1
Beyer, S; Bleich, S; de Zwaan, M; Frieling, H; Hillemacher, T; Jacoby, GE; Kornhuber, J; Römer, KD; Wilhelm, J	1
Baker, JS; Cowan, D; Davies, B; Graham, MR; Hullin, D; Kicman, A	1
Dimopoulos, N; Gazi, F; Kalofoutis, A; Lea, RW; Papadimitriou, A; Piperi, C; Psarra, V; Salonicioti, A	1
Geerlings, MI; Grobbee, DE; Kamphuis, MH; Kromhout, D	1
Halsted, CH; Nygård, OK; Peerson, JM; Refsum, H; Smith, AD; Tell, GS; Ueland, PM; Vollset, SE; Warden, CH; Wong, DH	1
Dwolatzky, T; Kaplan, Z; Kotler, M; Levine, J; Roitman, S; Sela, BA; Spivak, B; Timinsky, I; Vishne, T	1
Das, UN	1
O'Brien, JT; Teper, E	1
Gunby, P	1
Bottiglieri, T; Lowenthal, D; Parnetti, L	1
Bender, DA	1
Bottiglieri, T; Carney, MW; Crellin, R; Laundy, M; Reynolds, EH; Toone, BK	1
Bamonti-Catena, F; Colucci, P; De Franceschi, M; De Vecchi, AF; Fasano, MA; Finazzi, S; Novembrino, C; Patrosso, C	1

Reviews

14 review(s) available for homocysteine and Depression

Article	Year
Association between homocysteine levels in acute stroke and poststroke depression: A systematic review and meta-analysis. Brain and behavior, 2022, Volume: 12, Issue:6 Topics: Depression; Homocysteine; Humans; Ischemic Stroke; Risk Factors; Stroke	2022
The association between serum homocysteine and depression: A systematic review and meta-analysis of observational studies. European journal of clinical investigation, 2021, Volume: 51, Issue:5 Topics: Depression; Depressive Disorder; Homocysteine; Humans; Hyperhomocysteinemia; Observational Studies as Topic; Risk Factors	2021
Nutritional interventions in depression and perinatal depression. The Yale journal of biology and medicine, 2013, Volume: 86, Issue:2 Topics: Brain; Depression; Depression, Postpartum; Fatty Acids, Unsaturated; Female; Homocysteine; Humans; Nutritional Physiological Phenomena; Pregnancy	2013
Homocysteine excess: delineating the possible mechanism of neurotoxicity and depression. Fundamental & clinical pharmacology, 2015, Volume: 29, Issue:6 Topics: Cysteine; Depression; Homocysteine; Humans; Hyperhomocysteinemia; Neurotoxicity Syndromes; S-Adenosylmethionine	2015
S-Adenosyl Methionine in the Therapy of Depression and Other Psychiatric Disorders. Drug development research, 2016, Volume: 77, Issue:7 Topics: Animals; Depression; DNA Methylation; Epigenesis, Genetic; Homocysteine; Humans; Mental Disorders; Methylation; S-Adenosylmethionine; Time Factors	2016
The methylation, neurotransmitter, and antioxidant connections between folate and depression. Alternative medicine review : a journal of clinical therapeutic, 2008, Volume: 13, Issue:3 Topics: Antioxidants; Biopterins; Depression; Folic Acid Deficiency; Homocysteine; Humans; Methionine; Methylation; Neurotransmitter Agents; S-Adenosylmethionine; Selective Serotonin Reuptake Inhibitors; Tetrahydrofolates	2008
Folic acid, neurodegenerative and neuropsychiatric disease. Current molecular medicine, 2009, Volume: 9, Issue:3 Topics: Aging; Alzheimer Disease; Animals; Brain; Clinical Trials as Topic; Dementia, Vascular; Depression; Female; Folic Acid; Homocysteine; Humans; Male; Mental Disorders; Molecular Structure; Neurodegenerative Diseases; Neuronal Plasticity; Stroke; Vitamin B Complex	2009
Choosing treatment for Alzheimer's patients and their caregivers. Geriatrics, 2003, Volume: 58 Suppl 1 Topics: Aged; Alzheimer Disease; Anti-Inflammatory Agents; Anticonvulsants; Antipsychotic Agents; Caregivers; Cholinesterase Inhibitors; Depression; Ginkgo biloba; Homocysteine; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Phytotherapy; Plant Extracts; Professional-Family Relations; Psychotic Disorders; Receptors, N-Methyl-D-Aspartate; Risk Factors; Social Support; Vitamin E	2003
Homocysteine and folate metabolism in depression. Progress in neuro-psychopharmacology & biological psychiatry, 2005, Volume: 29, Issue:7 Topics: Animals; Depression; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Methylation; Models, Biological; Neurotransmitter Agents; Vitamin B 12 Deficiency	2005
The Hordaland Homocysteine Study: a community-based study of homocysteine, its determinants, and associations with disease. The Journal of nutrition, 2006, Volume: 136, Issue:6 Suppl Topics: Adult; Aged; Aging; Bone Density; Cardiovascular Diseases; Cognition Disorders; Depression; Disease; Female; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Mortality; Norway; Osteoporosis; Pregnancy; Pregnancy Complications; Risk Factors	2006
Folic acid and polyunsaturated fatty acids improve cognitive function and prevent depression, dementia, and Alzheimer's disease--but how and why? Prostaglandins, leukotrienes, and essential fatty acids, 2008, Volume: 78, Issue:1 Topics: Alzheimer Disease; Animals; Arachidonic Acid; Cognition; Dementia; Depression; Docosahexaenoic Acids; Eicosapentaenoic Acid; Fatty Acids, Omega-3; Fatty Acids, Unsaturated; Folic Acid; Homocysteine; Humans; Inflammation Mediators; Nitric Oxide	2008
Vascular factors and depression. International journal of geriatric psychiatry, 2008, Volume: 23, Issue:10 Topics: Autonomic Nervous System; Biomarkers; Cytokines; Depression; Endothelium, Vascular; Fatty Acids, Omega-3; Genetic Predisposition to Disease; Homocysteine; Humans; Hydrocortisone; Risk Factors; Vascular Diseases	2008
Role of homocysteine in age-related vascular and non-vascular diseases. Aging (Milan, Italy), 1997, Volume: 9, Issue:4 Topics: Aged; Aging; Alcoholism; Central Nervous System; Cerebrovascular Disorders; Cognition; Coronary Disease; Depression; Estrogens; Female; Folic Acid Deficiency; Homocysteine; Humans; Kidney Failure, Chronic; Male; Methylation; Peripheral Vascular Diseases; Renal Replacement Therapy; Vascular Diseases; Vitamin B 12 Deficiency	1997
Non-nutritional uses of vitamin B6. The British journal of nutrition, 1999, Volume: 81, Issue:1 Topics: Animals; Carpal Tunnel Syndrome; Depression; Drug Interactions; Female; Glucose Tolerance Test; Homocysteine; Humans; Hypertension; Male; Nutrition Policy; Premenstrual Syndrome; Pyridoxine; Rats; Tryptophan	1999

Trials

10 trial(s) available for homocysteine and Depression

Article	Year
Elevated circulating homocysteine and high-sensitivity C-reactive protein jointly predicts post-stroke depression among Chinese patients with acute ischemic stroke. Clinica chimica acta; international journal of clinical chemistry, 2018, Volume: 479 Topics: Acute Disease; Brain Ischemia; C-Reactive Protein; China; Depression; Female; Homocysteine; Humans; Male; Middle Aged; Predictive Value of Tests; Stroke	2018
Longitudinal relationship of diet and oxidative stress with depressive symptoms in patients with metabolic syndrome after following a weight loss treatment: the RESMENA project. Clinical nutrition (Edinburgh, Scotland), 2014, Volume: 33, Issue:6 Topics: Blood Glucose; Caloric Restriction; Cholesterol; Depression; Diet, Reducing; Energy Intake; Fatty Acids, Omega-3; Female; Folic Acid; Homocysteine; Humans; Linear Models; Longitudinal Studies; Male; Malondialdehyde; Metabolic Syndrome; Middle Aged; Oxidative Stress; Treatment Outcome; Weight Loss	2014
Effects of Four-Week Supplementation with a Multi-Vitamin/Mineral Preparation on Mood and Blood Biomarkers in Young Adults: A Randomised, Double-Blind, Placebo-Controlled Trial. Nutrients, 2015, Oct-30, Volume: 7, Issue:11 Topics: Adolescent; Adult; Affect; Biomarkers; Cognition; Depression; Dietary Supplements; Double-Blind Method; Female; Homocysteine; Humans; Male; Minerals; Reference Values; Trace Elements; Vitamin B Complex; Vitamins; Young Adult	2015
Predictive value of homocysteine for depression after acute coronary syndrome. Oncotarget, 2016, Oct-18, Volume: 7, Issue:42 Topics: Acute Coronary Syndrome; Adult; Aged; Antidepressive Agents; Biomarkers, Tumor; Citalopram; Depression; Double-Blind Method; Female; Follow-Up Studies; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Predictive Value of Tests; Republic of Korea	2016
The B-VITAGE trial: a randomized trial of homocysteine lowering treatment of depression in later life. Trials, 2010, Jan-25, Volume: 11 Topics: Age Factors; Antidepressive Agents; Biomarkers; Citalopram; Depression; Double-Blind Method; Drug Therapy, Combination; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Medication Adherence; Middle Aged; Psychiatric Status Rating Scales; Research Design; Severity of Illness Index; Time Factors; Treatment Outcome; Vitamin B 12; Vitamin B 6; Vitamin B Complex; Western Australia	2010
A randomized placebo controlled trial of homocysteine lowering to reduce cognitive decline in older demented people. Clinical nutrition (Edinburgh, Scotland), 2011, Volume: 30, Issue:3 Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cognition Disorders; Dementia, Vascular; Depression; Double-Blind Method; Drug Therapy, Combination; Female; Folic Acid; Homocysteine; Hong Kong; Humans; Hyperhomocysteinemia; Male; Neuropsychological Tests; Patient Dropouts; Vitamin B 12; Vitamin B Complex	2011
Testing homocysteine-induced neurotransmitter deficiency, and depression of mood hypothesis in clinical practice. Age and ageing, 2011, Volume: 40, Issue:6 Topics: Aged; Aged, 80 and over; Biomarkers; Critical Illness; Depression; Dietary Supplements; Dose-Response Relationship, Drug; Double-Blind Method; Female; Homocysteine; Humans; Incidence; Inpatients; Male; Mood Disorders; Neurotransmitter Agents; Outcome Assessment, Health Care; Treatment Outcome; Vitamin B Complex	2011
Recombinant human growth hormone in abstinent androgenic-anabolic steroid use: psychological, endocrine and trophic factor effects. Current neurovascular research, 2007, Volume: 4, Issue:1 Topics: Adult; Anabolic Agents; Androgens; Anxiety; Blood Glucose; Body Composition; C-Reactive Protein; Depression; Endocrine System; Homocysteine; Hormones; Human Growth Hormone; Humans; Insulin-Like Growth Factor I; Lipids; Male; Sodium; Substance-Related Disorders; Surveys and Questionnaires; Urea	2007
Homocysteine, folate, methylation, and monoamine metabolism in depression. Journal of neurology, neurosurgery, and psychiatry, 2000, Volume: 69, Issue:2 Topics: Adult; Biogenic Monoamines; Blood Cell Count; Body Weight; Depression; Erythrocytes; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Methoxyhydroxyphenylglycol; Methylation; Middle Aged; S-Adenosylmethionine; Vitamin B 12	2000
Folate supplementation in peritoneal dialysis patients with normal erythrocyte folate: effect on plasma homocysteine. Nephron, 2001, Volume: 89, Issue:3 Topics: Anorexia; Depression; Down-Regulation; Erythrocytes; Female; Folic Acid; Homocysteine; Humans; Kidney Diseases; Male; Middle Aged; Peritoneal Dialysis; Sleep Initiation and Maintenance Disorders; Vitamin B 12	2001

Other Studies

58 other study(ies) available for homocysteine and Depression

Article	Year
Fluorescence probe for selectively monitoring biothiols within cells and mouse depression diagnosis. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022, Volume: 154 Topics: Animals; Cysteine; Depression; Fluorescent Dyes; Glutathione; HeLa Cells; Homocysteine; Humans; Mice; Spectrometry, Fluorescence	2022
Associations of C-reactive protein and homocysteine concentrations with the impairment of intrinsic capacity domains over a 5-year follow-up among community-dwelling older adults at risk of cognitive decline (MAPT Study). Experimental gerontology, 2019, Volume: 127 Topics: Activities of Daily Living; Aged; Biomarkers; Body Mass Index; C-Reactive Protein; Cognitive Dysfunction; Depression; Female; Follow-Up Studies; Geriatric Assessment; Hand Strength; Homocysteine; Humans; Independent Living; Inflammation; Male; Mobility Limitation; Neuropsychological Tests; Prospective Studies; Risk Factors; Time Factors	2019
A prospective observational study of on-treatment plasma homocysteine levels as a biomarker of toxicity, depression and vitamin supplementation lead-in time pre pemetrexed, in patients with non-small cell lung cancer and malignant mesothelioma. PloS one, 2019, Volume: 14, Issue:11 Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Carcinoma, Non-Small-Cell Lung; Depression; Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Lung Neoplasms; Male; Mesothelioma; Mesothelioma, Malignant; Middle Aged; Pemetrexed; Prospective Studies; Treatment Outcome; Vitamin B 12; Vitamins	2019
Homocysteine-mediated gender-dependent effects of prenatal maternal depression on motor development in newborn infants. Journal of affective disorders, 2020, 02-15, Volume: 263 Topics: Adult; Depression; Female; Homocysteine; Humans; Infant; Infant, Newborn; Male; Mothers; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Vitamins	2020
Folic acid ameliorates depression-like behaviour in a rat model of chronic unpredictable mild stress. BMC neuroscience, 2020, 01-15, Volume: 21, Issue:1 Topics: Animals; Antidepressive Agents; Antidepressive Agents, Second-Generation; Behavior, Animal; Biogenic Monoamines; Brain; Citalopram; Depression; Disease Models, Animal; Folic Acid; Homocysteine; Male; Rats, Sprague-Dawley; Stress, Psychological	2020
The relationship between dietary patterns and depression mediated by serum levels of Folate and vitamin B12. BMC psychiatry, 2020, 02-13, Volume: 20, Issue:1 Topics: Adolescent; Adult; Aged; Case-Control Studies; Depression; Depressive Disorder, Major; Female; Folic Acid; Homocysteine; Humans; Iran; Logistic Models; Male; Middle Aged; Tryptophan; Vitamin B 12; Young Adult	2020
Homocysteine, but not MTHFR gene polymorphism, influences depressive symptoms in patients with schizophrenia. Journal of affective disorders, 2020, 07-01, Volume: 272 Topics: Depression; Folic Acid; Genotype; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Schizophrenia	2020
Interactive effects of elevated homocysteine and late-life depression on cognitive impairment. Journal of affective disorders, 2020, 12-01, Volume: 277 Topics: Aged; Cognition; Cognitive Dysfunction; Depression; Homocysteine; Humans; Neuropsychological Tests	2020
Total Plasma Homocysteine and Depressive Symptoms in Older Hispanics. Journal of Alzheimer's disease : JAD, 2021, Volume: 82, Issue:s1 Topics: Aged; Aging; Biomarkers; Cohort Studies; Cross-Sectional Studies; Depression; Female; Hispanic or Latino; Homocysteine; Humans; Male; Middle Aged; Venezuela	2021
Combination of High-Sensitivity C-Reactive Protein and Homocysteine Predicts the Post-Stroke Depression in Patients with Ischemic Stroke. Molecular neurobiology, 2018, Volume: 55, Issue:4 Topics: Adult; Aged; Brain Ischemia; C-Reactive Protein; Depression; Female; Follow-Up Studies; Homocysteine; Humans; Incidence; Logistic Models; Male; Middle Aged; Multivariate Analysis; ROC Curve; Stroke	2018
Associations between serum homocysteine levels and anxiety and depression among children and adolescents in Taiwan. Scientific reports, 2017, 08-21, Volume: 7, Issue:1 Topics: Adolescent; Anxiety; Asian People; Child; Cross-Sectional Studies; Depression; Female; Homocysteine; Humans; Linear Models; Male; Schools; Students; Surveys and Questionnaires; Taiwan	2017
Probiotics Affect One-Carbon Metabolites and Catecholamines in a Genetic Rat Model of Depression. Molecular nutrition & food research, 2018, Volume: 62, Issue:7 Topics: Animals; Antidepressive Agents; Behavior, Animal; Bifidobacterium longum; Biomarkers; Depression; Dopamine; Dopamine Antagonists; Freeze Drying; Hippocampus; Homocysteine; Lactobacillus helveticus; Liver; Male; Methylation; Neurons; Norepinephrine; Prefrontal Cortex; Probiotics; Random Allocation; Rats, Mutant Strains; S-Adenosylmethionine	2018
Association between increased plasma levels of homocysteine and depression observed in individuals with primary lactose malabsorption. PloS one, 2018, Volume: 13, Issue:8 Topics: Adult; Body Mass Index; Depression; Female; Folic Acid; Genetic Association Studies; Genetic Predisposition to Disease; Homocysteine; Humans; Lactase; Lactose Intolerance; Male; Middle Aged; Risk Factors; Vitamin B 12	2018
B-vitamins in Relation to Depression in Older Adults Over 60 Years of Age: The Trinity Ulster Department of Agriculture (TUDA) Cohort Study. Journal of the American Medical Directors Association, 2019, Volume: 20, Issue:5 Topics: Aged; Aging; Biomarkers; Cognitive Dysfunction; Cohort Studies; Cross-Sectional Studies; Depression; Female; Folic Acid; Homocysteine; Humans; Ireland; Male; Middle Aged; Nutritional Status; Pyridoxal Phosphate; Pyridoxine; Vitamin B 12; Vitamin B Complex	2019
[Modulation of hippocampal glutamate and NMDA/AMPA receptor by homocysteine in chronic unpredictable mild stress-induced rat depression]. Sheng li xue bao : [Acta physiologica Sinica], 2013, Feb-25, Volume: 65, Issue:1 Topics: Animals; Behavior, Animal; Depression; Dizocilpine Maleate; Glutamic Acid; Hippocampus; Homocysteine; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Stress, Psychological	2013
Hyperhomocysteinemia is a result, rather than a cause, of depression under chronic stress. PloS one, 2014, Volume: 9, Issue:10 Topics: Animals; Behavior, Animal; Betaine-Homocysteine S-Methyltransferase; Chronic Disease; Depression; Disease Models, Animal; Homocysteine; Hyperhomocysteinemia; Male; Methionine; Rats, Wistar; Recombinant Proteins; Sertraline; Stress, Psychological	2014
Age dependent levels of plasma homocysteine and cognitive performance. Behavioural brain research, 2015, Apr-15, Volume: 283 Topics: Adolescent; Adult; Aged; Aging; Attention; C-Reactive Protein; Cognition; Depression; Female; Folic Acid; Homocysteine; Humans; India; Interleukin-6; Male; Mental Recall; Middle Aged; Neuropsychological Tests; Psychiatric Status Rating Scales; Surveys and Questionnaires; Vitamin B 12; Young Adult	2015
Serum Levels of High-sensitivity C-Reactive Protein at Admission Are More Strongly Associated with Poststroke Depression in Acute Ischemic Stroke than Homocysteine Levels. Molecular neurobiology, 2016, Volume: 53, Issue:4 Topics: Aged; Aged, 80 and over; C-Reactive Protein; Depression; Female; Homocysteine; Hospitalization; Humans; Logistic Models; Male; Middle Aged; Multivariate Analysis; ROC Curve; Stroke	2016
Altered one-carbon metabolism in posttraumatic stress disorder. Journal of affective disorders, 2015, Sep-15, Volume: 184 Topics: Adult; Case-Control Studies; Dehydroepiandrosterone; Depression; Female; Folic Acid; Homocysteine; Humans; Hydrocortisone; Hypothalamo-Hypophyseal System; Male; Middle Aged; Pituitary-Adrenal System; Psychological Trauma; Risk Factors; Stress Disorders, Post-Traumatic; Vitamin B 12; Vitamin B 6	2015
Effects of Multivitamin Supplements on Cognitive Function, Serum Homocysteine Level, and Depression of Korean Older Adults With Mild Cognitive Impairment in Care Facilities. Journal of nursing scholarship : an official publication of Sigma Theta Tau International Honor Society of Nursing, 2016, Volume: 48, Issue:3 Topics: Aged; Cognitive Dysfunction; Depression; Dietary Supplements; Drug Therapy, Combination; Female; Folic Acid; Homocysteine; Humans; Male; Republic of Korea; Residential Facilities; Treatment Outcome; Vitamin B 12; Vitamin B 6	2016
Vitamin B European journal of clinical nutrition, 2017, Volume: 71, Issue:4 Topics: Age Factors; Aged; Aged, 80 and over; Aging; Cross-Sectional Studies; Depression; Female; Homocysteine; Humans; Incidence; Linear Models; Longitudinal Studies; Male; Multivariate Analysis; Netherlands; Proportional Hazards Models; Prospective Studies; Vitamin B 12	2017
Serum levels of homocysteine at admission are associated with post-stroke depression in acute ischemic stroke. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2017, Volume: 38, Issue:5 Topics: Aged; Brain Ischemia; Depression; Female; Follow-Up Studies; Homocysteine; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Patient Admission; Psychiatric Status Rating Scales; ROC Curve; Statistics, Nonparametric; Stroke; Tomography, X-Ray Computed	2017
C-reactive protein: vascular risk marker in elderly patients with mental illness. Dementia and geriatric cognitive disorders, 2008, Volume: 26, Issue:3 Topics: Adult; Aged; Aged, 80 and over; Aging; Alzheimer Disease; C-Reactive Protein; Cerebrovascular Disorders; Cognition Disorders; Cystatin C; Depression; Female; Homocysteine; Humans; Male; Mental Disorders; Middle Aged; Risk Factors	2008
Homocysteine and cognitive impairment. Relation with diagnosis and neuropsychological performance. Dementia and geriatric cognitive disorders, 2008, Volume: 26, Issue:6 Topics: Activities of Daily Living; Aged; Biomarkers; Cognition Disorders; Depression; Female; Homocysteine; Humans; Hypertension; Male; Memory; Neuropsychological Tests; Psychiatric Status Rating Scales; Psychomotor Performance; Regression Analysis; Risk Factors	2008
Depression, homocysteine concentration, and cardiovascular events. JAMA, 2009, Apr-15, Volume: 301, Issue:15 Topics: Biomarkers; Coronary Disease; Depression; Depressive Disorder, Major; Homocysteine; Humans; Risk Factors	2009
Homocysteine and cognitive impairment in Parkinson's disease: a biochemical, neuroimaging, and genetic study. Movement disorders : official journal of the Movement Disorder Society, 2009, Jul-30, Volume: 24, Issue:10 Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Aged; Aged, 80 and over; Brain; Carbon-Nitrogen Ligases; Case-Control Studies; Cognition Disorders; Cystathionine beta-Synthase; Depression; Female; Folic Acid; Homocysteine; Humans; Immunoassay; Logistic Models; Magnetic Resonance Imaging; Male; Mental Status Schedule; Middle Aged; Neuropsychological Tests; Parkinson Disease; Polymorphism, Genetic; Severity of Illness Index; Vitamin B 12; Vitamin B 6	2009
Folate, vitamin B12, homocysteine, and depressive symptoms in a population sample of older Chinese adults. Journal of the American Geriatrics Society, 2009, Volume: 57, Issue:5 Topics: Aged; Cross-Sectional Studies; Depression; Female; Folic Acid; Homocysteine; Humans; Logistic Models; Male; Middle Aged; Risk Factors; Singapore; Vitamin B 12	2009
Serum folate and homocysteine and depressive symptoms among Japanese men and women. European journal of clinical nutrition, 2010, Volume: 64, Issue:3 Topics: Adult; Aged; Cross-Sectional Studies; Depression; Female; Folic Acid; Health Status; Health Surveys; Homocysteine; Humans; Japan; Logistic Models; Male; Middle Aged; Multivariate Analysis; Nutritional Status; Odds Ratio; Prevalence; Sex Factors; Young Adult	2010
Homocysteine and cognitive function in geriatric depression. Neuropsychobiology, 2010, Volume: 61, Issue:2 Topics: Aged; Attention; Cognition Disorders; Depression; Female; Geriatrics; Homocysteine; Humans; Immunoenzyme Techniques; Language; Male; Middle Aged; Neuropsychological Tests	2010
Depression, Parkinson disease, Alzheimer disease. The homocysteine hypothesis. Neurosciences (Riyadh, Saudi Arabia), 2010, Volume: 15, Issue:3 Topics: Alzheimer Disease; Depression; Homocysteine; Humans; Parkinson Disease	2010
Serum folate, vitamin B-12, and homocysteine and their association with depressive symptoms among U.S. adults. Psychosomatic medicine, 2010, Volume: 72, Issue:9 Topics: Adult; Age Factors; Aged; Aged, 80 and over; Depression; Diagnostic and Statistical Manual of Mental Disorders; Female; Folic Acid; Health Status; Homocysteine; Humans; Logistic Models; Male; Middle Aged; Nutrition Surveys; Poverty; Psychiatric Status Rating Scales; Severity of Illness Index; Sex Factors; Surveys and Questionnaires; United States; Vitamin B 12	2010
No relation between folate and homocysteine levels and depression in early pregnant women. Bioscience trends, 2010, Volume: 4, Issue:6 Topics: Adult; Cross-Sectional Studies; Depression; Diet; Female; Folic Acid; Homocysteine; Humans; Japan; Odds Ratio; Pregnancy; Pregnancy Complications; Pregnancy Trimester, First; Psychiatric Status Rating Scales; Vitamin B 12; Vitamin B 6	2010
The folate hydrolase 1561C>T polymorphism is associated with depressive symptoms in Puerto Rican adults. Psychosomatic medicine, 2011, Volume: 73, Issue:5 Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Aged; Boston; Cross-Sectional Studies; Depression; Female; Folate Receptor 1; Folic Acid; Folic Acid Deficiency; gamma-Glutamyl Hydrolase; Gene Frequency; Genotype; Glutamate Carboxypeptidase II; Homocysteine; Humans; Linear Models; Logistic Models; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Single Nucleotide; Proton-Coupled Folate Transporter; Psychiatric Status Rating Scales; Pteroylpolyglutamic Acids; Puerto Rico; Pyridoxal Phosphate; Reduced Folate Carrier Protein; Vitamin B 12	2011
Increased total homocysteine level is associated with clinical status and severity of white matter changes in symptomatic patients with subcortical small vessel disease. Clinical neurology and neurosurgery, 2011, Volume: 113, Issue:9 Topics: Age Factors; Aged; Biomarkers; Brain; Cerebral Small Vessel Diseases; Cognition; Depression; Female; Genotype; Homocysteine; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Male; Methylenetetrahydrofolate Dehydrogenase (NAD+); Middle Aged; Neuropsychological Tests; Odds Ratio; Psychiatric Status Rating Scales; Serbia; Sex Factors	2011
Cognitive dysfunction and depression in adult kidney transplant recipients: baseline findings from the FAVORIT Ancillary Cognitive Trial (FACT). Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation, 2012, Volume: 22, Issue:2 Topics: Cognition Disorders; Cross-Sectional Studies; Depression; Dietary Supplements; Female; Glomerular Filtration Rate; Homocysteine; Humans; Hyperhomocysteinemia; Kidney; Kidney Diseases; Kidney Transplantation; Logistic Models; Male; Middle Aged; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Vitamin B Deficiency; Vitamins	2012
Relationship between serum homocysteine levels and depressive symptoms: the Cooper Center Longitudinal Study. The Journal of clinical psychiatry, 2012, Volume: 73, Issue:5 Topics: Adult; Aged; Aged, 80 and over; Cross-Sectional Studies; Depression; Homocysteine; Humans; Linear Models; Logistic Models; Middle Aged; Multivariate Analysis; Sex Distribution; Texas	2012
Rapid cycling bipolar affective disorder and recurrent strokes secondary to high blood homocysteine. Journal of mental health (Abingdon, England), 2014, Volume: 23, Issue:5 Topics: Bipolar Disorder; Depression; Homocysteine; Humans; Male; Middle Aged; Stroke	2014
Risk profiles for mild cognitive impairment vary by age and sex: the Sydney Memory and Ageing study. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2012, Volume: 20, Issue:10 Topics: Age Factors; Aged; Aged, 80 and over; Apolipoprotein E4; Australia; Cognitive Dysfunction; Cross-Sectional Studies; Depression; Female; Heart Diseases; Homocysteine; Humans; Male; Neuropsychological Tests; Olfactory Perception; Prevalence; Residence Characteristics; Risk Factors; Sex Characteristics; Visual Acuity; Walking	2012
Status of vitamins B-12 and B-6 but not of folate, homocysteine, and the methylenetetrahydrofolate reductase C677T polymorphism are associated with impaired cognition and depression in adults. The Journal of nutrition, 2012, Volume: 142, Issue:8 Topics: Adult; Aged; Cognition Disorders; Cohort Studies; Cross-Sectional Studies; Depression; Female; Folic Acid; Gene Expression Regulation, Enzymologic; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Vitamin B 12; Vitamin B 6	2012
Aspirin decreases the risk of depression in older men with high plasma homocysteine. Translational psychiatry, 2012, Aug-14, Volume: 2 Topics: Aged; Aged, 80 and over; Antidepressive Agents; Aspirin; Australia; Cross-Sectional Studies; Depression; Depressive Disorder; Homocysteine; Humans; Hyperhomocysteinemia; Logistic Models; Male; Platelet Aggregation Inhibitors; Risk; Vitamin B Complex	2012
[Concentration increase in Hcy and anti-CCP antibody in the serum of depression rat model induced by chronic unpredictable mild stress]. Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2012, Volume: 37, Issue:8 Topics: Animals; Autoantibodies; Depression; Disease Models, Animal; Fluoxetine; Homocysteine; Male; Peptides, Cyclic; Rats; Rats, Sprague-Dawley; Stress, Physiological	2012
Cognitive function in an elderly population: interaction between vitamin B12 status, depression, and apolipoprotein E ε4: the Hordaland Homocysteine Study. Psychosomatic medicine, 2013, Volume: 75, Issue:1 Topics: Aged; Apolipoprotein E4; Cognition; Cognition Disorders; Cross-Sectional Studies; Depression; Female; Homocysteine; Humans; Linear Models; Male; Methylmalonic Acid; Neuropsychological Tests; Norway; Regression Analysis; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency	2013
Homocysteinemia in psychiatric disorders: association with dementia and depression, but not schizophrenia in female patients. Journal of neural transmission (Vienna, Austria : 1996), 2003, Volume: 110, Issue:12 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Dementia; Depression; Female; Homocysteine; Humans; Middle Aged; Risk Factors; Schizophrenia	2003
Association between homocysteine, depression, and cognitive function in community-dwelling older women from Australia. Journal of the American Geriatrics Society, 2004, Volume: 52, Issue:2 Topics: Aged; Australia; Cognition; Depression; Female; Homocysteine; Humans	2004
Fatty acids and homocysteine levels in patients with recurrent depression: an explorative pilot study. Prostaglandins, leukotrienes, and essential fatty acids, 2004, Volume: 70, Issue:4 Topics: Adult; Case-Control Studies; Depression; Fatty Acids; Fatty Acids, Unsaturated; Female; Homocysteine; Humans; Male; Middle Aged; Pilot Projects; Recurrence	2004
Homocysteine, Alzheimer genes and proteins, and measures of cognition and depression in older men. Journal of Alzheimer's disease : JAD, 2004, Volume: 6, Issue:3 Topics: Aged; Alzheimer Disease; Amyloid beta-Protein Precursor; Apolipoproteins E; Cognition Disorders; Cross-Sectional Studies; Depression; Gene Expression; Homocysteine; Humans; Male; Neuropsychological Tests; Point Mutation; Polymerase Chain Reaction; Severity of Illness Index; Surveys and Questionnaires; Tetrahydrofolates	2004
Elevated plasma homocysteine level in patients with Parkinson disease: motor, affective, and cognitive associations. Archives of neurology, 2004, Volume: 61, Issue:6 Topics: Aged; Cognition Disorders; Depression; Female; Homocysteine; Humans; Male; Middle Aged; Mood Disorders; Motor Skills Disorders; Parkinson Disease; Prospective Studies; Psychiatric Status Rating Scales	2004
Homocysteine and disability in hospitalized geriatric patients. Metabolism: clinical and experimental, 2004, Volume: 53, Issue:8 Topics: Activities of Daily Living; Age Factors; Aged; Aged, 80 and over; Body Mass Index; Cognition; Comorbidity; Depression; Disability Evaluation; Female; Homocysteine; Hospitalization; Humans; Linear Models; Male; Neuropsychological Tests; Nutritional Status; Psychiatric Status Rating Scales; Sex Factors; Socioeconomic Factors	2004
Plasma folate concentrations are associated with depressive symptoms in elderly Latina women despite folic acid fortification. The American journal of clinical nutrition, 2004, Volume: 80, Issue:4 Topics: Acculturation; Aged; Aging; California; Cross-Sectional Studies; Depression; Diet; Female; Folic Acid; Folic Acid Deficiency; Food, Fortified; Hispanic or Latino; Homocysteine; Humans; Logistic Models; Male; Middle Aged; Sex Factors; Vitamin B 12	2004
Contribution of the MTHFR gene to the causal pathway for depression, anxiety and cognitive impairment in later life. Neurobiology of aging, 2005, Volume: 26, Issue:2 Topics: Aged; Aged, 80 and over; Aging; Anxiety; Chi-Square Distribution; Cognition Disorders; Cross-Sectional Studies; Depression; DNA Mutational Analysis; Female; Genotype; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Neuropsychological Tests; Personality Inventory; Pteroylpolyglutamic Acids; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Vitamin B 12	2005
Association between depressive symptoms and serum concentrations of homocysteine in men: a population study. The American journal of clinical nutrition, 2004, Volume: 80, Issue:6 Topics: Cohort Studies; Cross-Sectional Studies; Depression; Finland; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Odds Ratio; Psychometrics; Surveys and Questionnaires; Vitamin B 12	2004
Subjective memory complaints with and without objective memory impairment: relationship with risk factors for dementia. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2005, Volume: 13, Issue:8 Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amnesia; Anxiety; Apolipoprotein E4; Apolipoproteins E; Cognition Disorders; Cross-Sectional Studies; Depression; Female; Homocysteine; Humans; Risk Factors; Self-Assessment; Sick Role; Western Australia	2005
Depressive symptoms may explain elevated plasma levels of homocysteine in females with eating disorders. Journal of psychiatric research, 2008, Volume: 42, Issue:1 Topics: Adolescent; Adult; Chromatography, High Pressure Liquid; Comorbidity; Depression; Feeding and Eating Disorders; Female; Homocysteine; Humans; Logistic Models; Psychometrics	2008
Correlation of folate, vitamin B12 and homocysteine plasma levels with depression in an elderly Greek population. Clinical biochemistry, 2007, Volume: 40, Issue:9-10 Topics: Aged; Depression; Female; Folic Acid; Greece; Homocysteine; Humans; Male; Middle Aged; Vitamin B 12	2007
Dietary intake of B(6-9-12) vitamins, serum homocysteine levels and their association with depressive symptoms: the Zutphen Elderly Study. European journal of clinical nutrition, 2008, Volume: 62, Issue:8 Topics: Aged; Aged, 80 and over; Depression; Diet; Folic Acid; Homocysteine; Humans; Linear Models; Logistic Models; Male; Nutritional Requirements; Nutritional Status; Vitamin B 12; Vitamin B 6; Vitamin B Complex; Vitamin B Deficiency	2008
Relations of glutamate carboxypeptidase II (GCPII) polymorphisms to folate and homocysteine concentrations and to scores of cognition, anxiety, and depression in a homogeneous Norwegian population: the Hordaland Homocysteine Study. The American journal of clinical nutrition, 2007, Volume: 86, Issue:2 Topics: Alcohol Drinking; Animals; Antigens, Surface; Anxiety; Cardiovascular Diseases; Cognition; Depression; DNA; DNA Primers; Exons; Female; Folic Acid; Genotype; Glutamate Carboxypeptidase II; Homocysteine; Humans; Linkage Disequilibrium; Male; Norway; Polymorphism, Genetic; Temperance	2007
Elevated serum homocysteine levels in male patients with PTSD. Depression and anxiety, 2008, Volume: 25, Issue:11 Topics: Adult; Alzheimer Disease; Chronic Disease; Depression; Homocysteine; Humans; Male; Middle Aged; Risk Factors; Schizophrenia; Stress Disorders, Post-Traumatic; Young Adult	2008
Lipoprotein patterns, plaque, homocysteine, and hormones among ongoing cardiology studies. JAMA, 1996, Oct-09, Volume: 276, Issue:14 Topics: Apolipoproteins E; Atrial Fibrillation; Cardiac Rehabilitation; Cardiology; Cardiovascular Diseases; Depression; Electrocardiography; Estrogens; Female; Homocysteine; Humans; Lipoproteins; Male; Obesity; Risk Factors; Sleep Apnea Syndromes; Tomography, Emission-Computed	1996