Page last updated: 2024-08-21

pyrazines and Depression

pyrazines has been researched along with Depression in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19904 (57.14)18.7374
1990's0 (0.00)18.2507
2000's1 (14.29)29.6817
2010's2 (28.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dang, H; Fu, S; Hao, C; Jiang, S; Wang, J1
Arai, Y; Hayashi, S; Hirose, W; Imai, S; Kassai, M; Kato, Y; Takata, M; Yamamoto, T; Yoshida, K1
Davis, M; Donovan, JL; Hamdy, FC; Lane, JA; Metcalfe, C; Mills, N; Neal, DE; Peters, TJ; Ronsmans, C; Sterne, JA1
Andreyeva, NI; Mashkovsky, MD1
Al-Shaltchi, B; Brändli, A; Fleischhauer, J1
McCoubrie, M; Snaith, RP1
Hsu, W; Itil, TM; Polvan, N1

Trials

1 trial(s) available for pyrazines and Depression

ArticleYear
Clinical and EEG effects of GB-94, a "tetracyclic" antidepressant (EEG model in discovery of a new psychotropic drug).
    Current therapeutic research, clinical and experimental, 1972, Volume: 14, Issue:7

    Topics: Adult; Aged; Amitriptyline; Antidepressive Agents; Blood Pressure; Cerebral Cortex; Clinical Trials as Topic; Computers; Depression; Dibenzazepines; Dibenzoxazepines; Drug Tolerance; Electroencephalography; Female; Humans; Male; Middle Aged; Personality Inventory; Psychiatric Status Rating Scales; Pyrazines; Tryptamines

1972

Other Studies

6 other study(ies) available for pyrazines and Depression

ArticleYear
Tetramethylpyrazine ameliorates depression by inhibiting TLR4-NLRP3 inflammasome signal pathway in mice.
    Psychopharmacology, 2019, Volume: 236, Issue:7

    Topics: Animals; Antidepressive Agents; Cytokines; Depression; Dose-Response Relationship, Drug; Hippocampus; Inflammasomes; Male; Mice; Mice, Inbred ICR; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Prefrontal Cortex; Pyrazines; Signal Transduction; Stress, Psychological; Toll-Like Receptor 4; Vasodilator Agents

2019
Synthesis, structure-activity relationships and biological evaluation of 4,5,6,7-tetrahydropyrazolopyrazines as metabotropic glutamate receptor 5 negative allosteric modulators.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Allosteric Regulation; Animals; Antidepressive Agents; Brain; Depression; Disease Models, Animal; Half-Life; Humans; Mice; Microsomes, Liver; Protein Binding; Pyrazines; Pyrazoles; Pyridines; Rats; Receptor, Metabotropic Glutamate 5; Structure-Activity Relationship

2016
A comparison of socio-demographic and psychological factors between patients consenting to randomisation and those selecting treatment (the ProtecT study).
    Contemporary clinical trials, 2006, Volume: 27, Issue:5

    Topics: Aged; Anxiety; Depression; Follow-Up Studies; Humans; Hydrazines; Male; Middle Aged; Patient Satisfaction; Patient Selection; Prostatic Neoplasms; Pyrazines; Quinolines; Randomized Controlled Trials as Topic; Socioeconomic Factors

2006
Pyrazidol, a new drug with antidepressant properties.
    Annali dell'Istituto superiore di sanita, 1978, Volume: 14, Issue:1

    Topics: Animals; Antidepressive Agents; Chemical Phenomena; Chemistry; Depression; Humans; Indoles; Monoamine Oxidase Inhibitors; Pyrazines; Rats

1978
[Report on a preliminary open clinical study of mianserin (GB 94), a tetracyclic antidepressant].
    Arzneimittel-Forschung, 1973, Volume: 23, Issue:12

    Topics: Adult; Aged; Animals; Antidepressive Agents; Anxiety; Azepines; Bipolar Disorder; Conflict, Psychological; Depression; Depressive Disorder, Major; Dopamine Antagonists; Electroencephalography; Feeding and Eating Disorders; Female; Humans; Mental Fatigue; Mice; Middle Aged; Pyrazines; Rats; Serologic Tests; Sleep Wake Disorders

1973
Antihypertensive drugs and depression.
    Psychological medicine, 1974, Volume: 4, Issue:4

    Topics: Adult; Aged; Antihypertensive Agents; Bethanidine; Chlorthalidone; Depression; Diuretics; Drug Therapy, Combination; Fatigue; Furosemide; Guanethidine; Humans; Hydrochlorothiazide; Methyldopa; Middle Aged; Phenobarbital; Potassium; Pyrazines; Reserpine; Self-Assessment; Sodium Chloride Symporter Inhibitors; Theobromine

1974