glutamic acid has been researched along with Depression in 243 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (1.23) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 22 (9.05) | 29.6817 |
| 2010's | 149 (61.32) | 24.3611 |
| 2020's | 69 (28.40) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, H; Zhou, Y | 1 |
| Andersen, ML; Dokkedal-Silva, V; Piovezan, RD; Tufik, S; Vitti-Ruela, BV | 1 |
| Du, X; Gamper, N; Huang, D; Ma, J; Niu, C; Sun, H; Wang, J; Zhang, H; Zhang, L; Zhang, Y; Zhu, T | 1 |
| Chai, JR; Chen, YQ; Deng, YZ; Du, JY; Fang, JF; Fang, JQ; Li, QL; Li, XP; Liu, JG; Liu, R; Liu, ZQ; Long, JD; Shao, XM; Sun, X; Wang, Q; Wang, YJ; Yao, SY; Zan, GY | 1 |
| Himmerich, H; Juruena, MF; Kan, C; Keeler, JL; Treasure, J | 1 |
| Bai, M; Chen, C; Chen, X; Chen, Z; Cheng, K; Fang, L; He, Y; Lan, T; Li, Y; Tian, Y; Wang, Y; Wu, Z; Xie, P; Xu, X; Yang, D; Yu, H; Zhao, L | 1 |
| Ho, YC; Kan, HW; Peng, WH | 1 |
| Chen, J; Cui, M; Gu, S; Hao, W; Mou, T; Sun, Y; Wang, J; Wei, B; Zhang, C; Zhang, Y; Zhao, T | 1 |
| Cai, D; Lou, W; Mao, X | 1 |
| Ishiguro, M; Kakizaki, R; Narimatsu, E; Nomura, K; Sawamoto, K; Takahashi, K; Uemura, S | 1 |
| Maratha, S; Sharma, V; Walia, V | 1 |
| Camargo, A; Rodrigues, ALS | 1 |
| Barredo, J; Carpenter, LL; Fukuda, AM; Gonsalves, MA; Harris, AD; Joyce, HE; White, TL | 1 |
| Brocki, K; Fällmar, D; Frick, A; Frick, M; Gingnell, M; Guath, M; Karlsson, B; Kleberg, JL; Klevebrant, L; Mårtensson, J; Möller, S; Pine, DS; Weis, J; Widegren, E | 1 |
| Boksha, IS; Burbaeva, GS; Chen, L; Dai, X; Dong, Y; Hou, Y; Lv, X; Omel'chenko, MA; Prokhorova, TA; Savushkina, OK; Tereshkina, EB; Vorobieva, EA; Wang, L; Zhong, G | 1 |
| Belloch, FB; Cortés-Erice, M; Díaz-Perdigon, T; Herzog, E; Puerta, E; Tordera, RM; Zhang, XM | 1 |
| Chen, B; Di, Z; Guo, Q; Hu, R; Jiang, S; Liu, J; Ma, R; Shi, M; Song, Z; Sun, S; Wu, X; Xu, H | 1 |
| Chen, ZG; Hong, H; Liu, CH; Liu, SM; Liu, X; Mu, RH; Tang, SS; Wang, H; Yuan, DH; Zeng, J; Zhao, JJ | 1 |
| Bian, X; Fang, Y; Li, N; Li, Y; Wang, X; Wu, JL; Zhang, X; Zhao, Y; Zhou, N; Zhou, T | 1 |
| Hu, L; Liu, Y; Lv, F; Ma, L; Pu, J; Shen, Y; Shi, Y; Xie, X; Yang, W; Zhang, H | 1 |
| Lv, S; Yao, K; Zhang, Y; Zhu, S | 1 |
| Bonanno, G; Bonifacino, T; Di Cesare Mannelli, L; Farina, C; Ghelardini, C; Micheli, L; Milanese, M; Scherz, MW; Torazza, C | 1 |
| Ching, J; Ho, CSH; Tay, GWN; Wee, HN | 1 |
| Kang, Y; Liu, J; Ou, M; Qiu, J; Wang, J; Yang, Y; Zhang, D; Zhou, C; Zhu, T | 1 |
| Chu, T; Dong, Y; Li, X; Liu, Q; Luo, X; Ren, Q; Wang, J; Xu, D; Zeng, Z; Zou, L | 1 |
| Altê, GA; Camargo, A; Dalmagro, AP; Rodrigues, ALS; Tasca, CI; Zeni, ALB | 1 |
| Candee, R; DeCenzo, M; Schreiber, M; Wilkenson, R | 1 |
| Menard, C; Paton, SE | 1 |
| Du, X; Gao, Y; Li, X; Li, Y; Liu, S; Wang, D; Xu, Y; Zhang, Y; Zhao, Y | 1 |
| Pavlova, I; Ruda-Kucerova, J | 1 |
| Ai, Z; Chen, C; Li, H; Liao, L; Luo, J; Song, Y; Su, D; Yang, M; Zhang, B; Zhang, H; Zhu, G | 1 |
| Jin, Y; Liu, C; Liu, Y; Wang, S; Wu, Z; Yang, Z; Zhang, T | 1 |
| Ai, K; Huang, W; Liu, G; Wang, J; Xu, K; Zhang, J | 1 |
| Czechowska, E; Pańczyszyn-Trzewik, P; Sowa-Kućma, M; Stachowicz, K | 1 |
| Boyko, M; Gruenbaum, BF; Merzlikin, I; Oleshko, A; Zlotnik, A | 1 |
| Chen, JX; Ding, XF; Li, J; Li, XJ; Liu, Y; Liu, YY; Qian, XY; Wang, XX; Zou, XJ | 1 |
| Cubała, WJ; Włodarczyk, A | 1 |
| Haegele, M; Moser, A; Schumacher, A; Spyth, J | 1 |
| Kalinina, TS; Kiselev, AV; Sergienko, VI; Stovbun, IS; Vedenkin, AS | 1 |
| Chen, C; Du, G; Gao, X; Qin, X; Tian, J; Yin, Q; Zhou, Y | 1 |
| Gong, W; Qin, X; Zhou, Y | 1 |
| Di, Z; Guo, Q; Jiang, S; Zhang, QA | 1 |
| De Berardis, D; Di Giannantonio, M; Fornaro, M; Fraticelli, S; Kim, YK; Martinotti, G; Orsolini, L; Perna, G; Pompili, M; Serafini, G; Tomasetti, C; Valchera, A; Vellante, F; Volpe, U | 1 |
| Bi, N; Chen, XT; Fan, A; Niu, K; Tao, H; Wang, HL; Wang, T | 1 |
| de Diego-Adeliño, J; Draganov, M; Portella, MJ; Puigdemont, D; Vicent-Gil, M; Vives-Gilabert, Y | 1 |
| Adusumilli, M; Deolal, P; Kumar, A; Mason, GF; Mishra, PK; Patel, AB | 1 |
| Alese, OO; Mabandla, MV; Mkhize, NV; Ngoupaye, GT; Rakgantsho, C; Zulu, S | 1 |
| Chen, ZK; Dong, H; Huang, ZL; Jiang, SY; Li, RX; Ni, J; Qu, WM; Wang, TX; Yuan, MY | 1 |
| Li, J; Sha, L; Xu, Q | 1 |
| Adell, A; Gordillo-Salas, M; Greer, J; Pascual-Antón, R; Ren, J | 1 |
| Aida, T; Aizawa, H; Cui, W; Itou, Y; Sugiyama, K; Sun, W; Tanaka, K; Terai, H; Toyoda, S; Yanagisawa, M | 1 |
| Baer, L; Benson, KL; Bottary, R; Eric Jensen, J; Gonenc, A; Schoerning, L; Winkelman, JW | 1 |
| Chen, NH; Chu, SF; Cui, LY; He, HY; He, WB; Wang, ZZ; Yang, B; Zhang, Z; Zhou, X | 1 |
| Han, D; Jung, J; Kim, SH; Kim, YT; Lee, C; Lee, J; Lim, DW; Park, J; Um, MY; Yoon, M | 1 |
| Di, Z; Guo, Q; Jiang, S; Lin, XM; Zhang, QA | 1 |
| Barker, PB; Edden, RAE; Gould, NF; Joo, JH; Kraut, MA; Leoutsakos, JS; Nassery, N; Oeltzschner, G; Rowland, LM; Smith, GS; Wijtenburg, SA; Workman, CI | 1 |
| Ding, Y; Geng, Y; Guan, J; Lai, L; Li, J; Qi, D; Rong, Y; Tang, Y; Wu, E; Wu, R; Yang, L; Zhou, T | 1 |
| Bai, M; Chen, C; Chen, X; Chen, Z; Cheng, K; He, Y; Lan, T; Li, Y; Tian, Y; Wang, Y; Wu, Z; Xie, P; Yu, H | 1 |
| Chuchmacz, J; Czarnecka, K; Szymański, P; Wójtowicz, P | 1 |
| Amodeo, P; Belardo, C; Boccella, S; Calignano, A; Cristiano, C; de Novellis, V; Di Marzo, V; Guida, F; Iannotta, M; Iannotti, FA; Infantino, R; Luongo, L; Maione, S; Marabese, I; Paino, S; Palazzo, E; Ricciardi, F; Vitale, RM | 1 |
| Liu, C; Wang, S; Wang, Y; Xin, Y; Yang, Z; Zhang, J | 1 |
| Adler, CM; Blom, TJ; Cecil, KM; DelBello, MP; Nery, FG; Patino, LR; Tallman, MJ | 1 |
| Coombes, BJ; Frye, MA; Geske, JR; Lanza, IR; Morgan, RJ; Port, JD; Singh, B; Voort, JLV | 1 |
| Campos, MM; Dagnino, APA; Freitas, RDS; Fritscher, GG; Irigaray, TQ; Neculqueo, GW; Volkweis, MCC | 1 |
| Bevilacqua, M; Bove, M; Colia, AL; Dimonte, S; Francavilla, M; Morgese, MG; Schiavone, S; Trabace, L; Tucci, P | 1 |
| Deng, J; Hökfelt, TGM; Lallemend, F; Li, C; Li, H; Li, X; Li, Y; Liu, B; Liu, Z; Luo, H; Svenningsson, P; Wang, CY; Wu, H; Wu, J; Xu, ZD; Yang, Y; Zhao, M | 1 |
| Gao, S; Guo, Y; Li, R; Li, W; Liu, J; Lyu, S; Tang, G; Yang, J; Zhang, L | 1 |
| Ağar, A; Akçay, G; Aydın Aslan, M; Bülbül, M; Derin, N; Özkan, A; Parlak, H; Sinen, O | 1 |
| Li, T; Li, X; Liu, Y; Luo, M; Luo, X; Lv, Y; Ren, Q; Rong, K; Zhang, W | 1 |
| Chen, Y; Deji, C; Guo, H; Peng, H; Wang, Y; Zhang, J; Zhang, Y | 1 |
| Arranz, MJ; Àvila-Parcet, A; de Diego-Adeliño, J; Draganov, M; Jubero, M; Portella, MJ; Puigdemont, D; Vives-Gilabert, Y | 1 |
| Chen, S; Eguchi, M; Fukunaga, A; Kabe, I; Kochi, T; Miki, T; Mizoue, T; Nanri, A | 1 |
| Adell, A; Bortolozzi, A; Castro, E; Díaz, Á; Florensa-Zanuy, E; Fullana, MN; Garro-Martínez, E; Paz, V; Pazos, Á; Pilar-Cuéllar, F; Ruiz-Bronchal, E; Senserrich, J | 1 |
| Gulyaeva, NV | 1 |
| Abdallah, CG; Carson, RE; DellaGioia, N; DeLorenzo, C; Esterlis, I; Krystal, JH; Matuskey, D; Nabulsi, N; Parsey, RV; Pietrzak, RH; Pittenger, C; Sanacora, G; Yang, J | 1 |
| Deng, JH; Gao, XJ; Han, Y; Li, SX; Liu, LJ; Lu, L; Meng, SQ; Shi, J; Sun, CY; Wen, Q; Xu, DF; Xu, LZ; Xue, YX; Yuan, K; Yuan, M; Zhang, RX; Zhao, M; Zhu, WL | 1 |
| Arcego, DM; Berlitz, C; Dalmaz, C; do Couto Nicola, F; Dos Santos Garcia, E; Gaelzer, MM; Hoppe, JB; Klein, CP; Krolow, R; Lampert, C; Lazzaretti, C; Toniazzo, AP | 1 |
| Braidy, N; Daglia, M; Di Lorenzo, A; Khanjani, S; Moghaddam, AH; Nabavi, SF; Nabavi, SM; Sureda, A | 1 |
| Geng, LY; Qian, FY; Qian, JF; Zhang, ZJ | 1 |
| Haiyan, Z; Hui, Z; Jiahui, C; Lei, W; Qiuxia, Z; Xiaoquan, Y; Xinlong, M; Yali, W; Yilong, Y | 1 |
| Cattani, D; Cesconetto, PA; De Oliveira, PA; Filho, DW; Leite, MC; Parisotto, EB; Prediger, RDS; Razzera, G; Rieg, CEH; Tavares, MK; Wendt, NC; Zamoner, A | 1 |
| Cheung, C; Ching, J; Chu, WCW; Hui, SCN; Lam, L; Lee, S; Mak, ADP; Northoff, G; Wu, J; Yeung, DKW | 1 |
| Costa, AP; Gonçalves, FM; Heinrich, IA; Kaster, MP; Leal, RB; Lopes, MW; Neis, VB; Peres, TV; Rieger, DK; Rodrigues, ALS | 1 |
| Belloch, FB; Díaz-Perdigón, T; Muñoz-Cobo, I; Puerta, E; Tordera, RM | 1 |
| Chau, YP; Chen, GD; Chou, D; Ho, YC; Hsieh, MC; Lai, CY; Lin, TB; Peng, HY | 1 |
| Bradley, KA; Gabbay, V; Kang, G; Mao, X; Ostrover, R; Shungu, DC | 1 |
| Chan, AW; LeDue, J; McGirr, A; Murphy, TH; Xie, Y | 1 |
| Bigio, B; Brichta, L; de Angelis, P; Greengard, P; Lau, T; Lee, FS; McEwen, BS; Nasca, C; Neve, RL; Ni, J; Okamoto, M; Soya, H; Zelli, D | 1 |
| Ajilore, O; Deshpande, R; Feusner, JD; Ly, R; Moody, T; Morfini, F; O'Neill, J; Tadayonnejad, R | 1 |
| Holloway, AL; Hong-Routson, S; Piao, CS; Wainwright, MS | 1 |
| Boutros, N; Der-Avakian, A; Kesby, JP; Lee, S; Markou, A; Semenova, S | 1 |
| Li, M; Liao, Q; Lou, Z; Lv, D; Shen, M; Wang, C; Wang, Z; Xiao, X; Yu, H; Zhang, Y; Zhou, D | 1 |
| Grueter, BA; Grueter, CA; Kashima, DT; Manz, KM; Turner, BD | 1 |
| Liu, L; Pu, J; Xie, P; Yang, L; Yuan, S; Zhang, H; Zhang, Y; Zhao, L; Zhou, C; Zhou, X | 1 |
| Hao, S; Liu, C; Wang, Y; Yang, Z; Zhang, T; Zhu, M | 1 |
| Argueta, J; Benítez-King, G; Cercós, MG; Cruz-Garduño, R; Dorantes-Barrón, AM; Dubocovich, ML; Estrada-Reyes, R; Oikawa-Sala, J; Quero-Chávez, D; Solís-Chagoyán, H; Trueta, C; Valdés-Tovar, M | 1 |
| Aboul-Fotouh, S; Asaad, T; Ghanem, MH; Habib, M; Kassim, SK | 1 |
| Dick, TE; Jacono, FJ; Litvin, DG; Smith, CB | 1 |
| Gao, SF; Kessels, HW; Lucassen, PJ; Qi, XR; Swaab, DF; Verwer, RWH; Zhao, J | 1 |
| Alger, JR; Johnson, MC; London, ED; O'Neill, J; Shen, Z; Tang, J | 1 |
| Abdallah, CG; Duman, RS; Krystal, JH; Sanacora, G | 1 |
| Chen, JL; Du, GH; Gao, Y; He, XY; Qin, XM; Tian, JS; Xiang, H | 1 |
| Cui, W; Hong, W; Li, MD; Liu, Z; Ning, Y; Wang, J | 1 |
| Caffino, L; Fumagalli, F; Guo, C; Homberg, JR; Que, L; Verheij, MMM | 1 |
| Pilc, A; Wierońska, JM | 1 |
| Brito, BM; Gobira, PH; Joca, SRL; Sartim, AG | 1 |
| Blumberger, DM; Daskalakis, ZJ; ElSalhy, M; Graff-Guerrero, A; Horita, N; Katayama, N; Kishimoto, T; Meyer, JH; Mimura, M; Miyazaki, T; Moriguchi, S; Nakajima, S; Noda, Y; Ogyu, K; Plitman, E; Sano, Y; Takamiya, A; Tarumi, R; Tsugawa, S; Wada, M | 1 |
| Barik, J; Broussot, L; Contesse, T; Faure, P; Fernandez, SP; Marie, H; Marti, F; Mouska, X; Soiza-Reilly, M | 1 |
| Bhakoo, KK; Duytschaever, H; Garnell, JF; Grandjean, J; Sekar, S; Seramani, S; Su, H; Ver Donck, L; Willems, R | 1 |
| Ali, AI; Cheng, Z; Chibaatar, E; Guo, Y; Le, K; Wang, J; Yu, D | 1 |
| Duan, S; Fu, JY; Hu, H; Li, KX; Li, XM; Pan, HQ; Shen, CJ; Sun, P; Sun, QX; Tang, MY; Xie, Y; Yang, JM; Yu, XD; Zhang, Y; Zheng, D; Zhu, Y | 1 |
| Galyamina, AG; Kovalenko, IL; Kudryavtseva, NN; Smagin, DA | 1 |
| Bellomo, A; Berardis, DD; Carano, A; Fiengo, ALC; Fornaro, M; Giannantonio, MD; Kim, YK; Martinotti, G; Montemitro, C; Nicola, MD; Orsolini, L; Perna, G; Pompili, M; Santone, C; Serafini, G; Tomasetti, C; Valchera, A; Vellante, F; Ventriglio, A | 1 |
| Duman, RS; Fogaça, MV; Hare, B; Shinohara, R | 1 |
| Chen, YP; Wang, C; Xu, JP | 1 |
| Forester, BP; Harper, DG; Jensen, E; Mellen, EJ; Ravichandran, C; Silveri, M | 1 |
| Boyko, M; Brotfain, E; Frank, D; Grinshpun, Y; Gruenbaum, BF; Kuts, R; Natanel, D; Shelef, I; Tsenter, P; Zlotnik, A; Zvenigorodsky, V | 1 |
| Cadioli, M; Cariati, M; Demartini, B; Ferrucci, R; Gambini, O; Goeta, D; Marceglia, S; Priori, A; Uggetti, C | 1 |
| Kashimoto, Y; Kitano, Y; Makino, M; Murasawa, H; Pawlak, A; Takahashi-Ito, K | 1 |
| Adell, A; Campa, L; Castro, E; Frago, C; Jiménez-Sánchez, L; López-Gil, X | 1 |
| Chen, H; Chen, J; Gong, CZ; Huang, XL; Li, MX; Li, Q; Li, RC; Li, Y; Li, YJ; Luo, C; Shi, LP; Sun, XJ; Wang, YN; Xiong, QJ; Zheng, YF | 1 |
| Han, XM; Lu, YN; Qin, YJ; Rang, Y; Wang, NX; Zhai, XJ; Zhang, XL; Zhu, Y | 1 |
| An, SC; Liu, H; Qiao, H; Wen, LM | 1 |
| Bigler, DC; Bunce, SC; Mack, J; Moore, GJ; Morton, DH; Muelly, ER; Strauss, KA | 1 |
| Salvadore, G; Singh, JB | 1 |
| Andreasen, JT; Bøgelund, T; Clausen, RP; Gynther, M; Mogensen, J; Nielsen, SD; Pickering, DS; Rygaard, A | 1 |
| Barnes, E; Christmas, D; Collier, J; Cowen, PJ; Godlewska, B; Klenerman, P; Near, J; Potokar, J; Taylor, MJ | 1 |
| Guan, LX; Jia, N; Li, H; Sun, HL; Tang, GK; Wang, D; Zhang, XH; Zhao, XY; Zhu, ZL | 1 |
| Duman, RS; Krystal, JH; Sanacora, G | 1 |
| Pehrson, AL; Sanchez, C | 1 |
| Chen, CZ; Cheng, WZ; Ding, J; Fan, W; Li, X; Liang, L; Mao, LY; Peng, WF; Wang, X | 1 |
| Bali, A; Jaggi, AS | 1 |
| Boulanger, Y; Chamard, E; Henry, L; Lassonde, M; Théoret, H | 1 |
| Bagga, P; Chakravarty, S; Khandelwal, N; Kumar, A; Maitra, S; Noronha, JM; Patel, AB; Veeraiah, P | 1 |
| Bortolatto, CF; Duarte, MM; Gai, BM; Heck, SO; Nogueira, CW; Stein, AL; Zeni, G | 1 |
| An, SC; Chen, HB; Li, F; Wu, S | 1 |
| Chen, X; Haroon, E; Hu, XP; Miller, AH; Pace, TW; Parekh, S; Spivey, JR; Woolwine, BJ | 1 |
| Di Prisco, S; Gabriel, C; Gatta, E; Maccari, S; Mairesse, J; Marrocco, J; Merega, E; Mocaër, E; Morley-Fletcher, S; Nicoletti, F; Pittaluga, A; Reynaert, ML | 1 |
| Brady, LS; Potter, WZ | 1 |
| Liu, XY; Qiu, LL; Sun, HL; Wang, N; Wang, XM; Yang, C; Yang, JJ; Zhang, GF | 1 |
| Gao, S; Peng, GJ; Qin, XM; Shi, BY; Tian, JS | 1 |
| Abraham, R; Nirogi, R; Shinde, A | 1 |
| Campos, MM; Klein, CP; Leite, CE; Maciel, IS; Souza, AH; Sperotto, ND | 1 |
| Chen, XY; Cheng, SY; Li, J; Wang, RD; Zeng, JW; Zhao, YD | 1 |
| Lu, XY; Wang, X; Zhang, D | 1 |
| Earnheart, JC; Kim, JY; Lal, R; Luellen, BA; Luscher, B; Murakami, S; Ren, Z; Sahir, N; Song, H | 1 |
| Hao, X; Luo, J; Min, S; Xie, F; Zhang, F; Zhu, X | 1 |
| An, SC; Li, JN; Li, Z | 1 |
| Malinow, R; Piriz, J; Proulx, CD; Shabel, SJ | 1 |
| Gao, X; Qiao, M; Sun, P; Wei, S; Xue, L; Zhang, H | 1 |
| Delpire, E; Hall, BJ; Hargroder, EA; Miller, OH; Wang, CC; Yang, L; Zhang, Y | 1 |
| Barati, M; Homberg, JR; Khojasteh, F; Mehrpouya, S; Mirzamohammadi, S; Nahavandi, A; Raufi, S; Soleimani, M | 1 |
| Báldi, R; Bluett, RJ; Colbran, RJ; Hermanson, DJ; Kingsley, PJ; Marnett, LJ; Patel, S; Ramikie, TS; Shonesy, BC; Winder, DG | 1 |
| Holst, B; Młyniec, K; Nowak, G; Singewald, N | 1 |
| Reardon, S | 1 |
| DuPont, CM; Femenía, T; Lindskog, M; Magara, S | 1 |
| Abaleira, HM; Andrade, VM; Carlessi, AS; Dal-Pizzol, F; Damiani, AP; dos Santos, MA; Gomes, Vde C; Landeira-Fernadez, J; Leffa, DD; Matias, BI; Michels, M; Quevedo, J; Réus, GZ; Tomaz, DB | 1 |
| Duffy, SL; Hermens, DF; Hickie, IB; Jayaweera, HK; Lagopoulos, J; Lewis, SJ; Naismith, SL; Norrie, L | 1 |
| Brüning, CA; Duarte, MM; Gai, BM; Martini, F; Nogueira, CW; Sampaio, TB; Soares, SM | 1 |
| Dalla, C; Ferreira, C; Kokras, N; Melo, A; Pêgo, JM; Sousa, N; Ventura-Silva, AP | 1 |
| Liu, C; Liu, WF | 1 |
| Amreen, B; Aperia, A; Chang, JC; Flajolet, M; Greengard, P; Gresack, J; Kim, D; Kim, J; Kim, Y; Lee, KW; Oh, YS; Westin, L | 1 |
| Mlyniec, K | 1 |
| Amchova, P; Babinska, Z; Havlickova, T; Jerabek, P; Kacer, P; Ruda-Kucerova, J; Sulcova, A; Sustkova-Fiserova, M; Syslova, K | 1 |
| Enohara, M; Fujita, Y; Hasegawa, T; Hashimoto, K; Hashimoto, T; Ishikawa, M; Iyo, M; Kanahara, N; Kimura, A; Nakazato, M; Niitsu, T; Sasaki, T; Shiina, A; Watanabe, H; Yoshida, T | 1 |
| Bigio, B; McEwen, BS; Nasca, C; Nisticò, R; Piccinin, S; Scaccianoce, S; Zelli, D | 1 |
| González-Sepúlveda, M; Marcos, J; Pozo, OJ; Valverde, O | 1 |
| Bethea, CL; Kohama, SG; Reddy, AP; Urbanski, HF | 1 |
| Chen, X; Felger, JC; Fleischer, CC; Haroon, E; Hu, XP; Miller, AH; Patel, T; Woolwine, BJ | 1 |
| Andersen, SL; Freund, N; Meda, S; Sonntag, K; Thompson, BS | 1 |
| Bao, AM; Wu, JL; Wu, SH; Yu, SY | 1 |
| Duman, RS; Gerhard, DM; Wohleb, ES | 1 |
| Fernández-Guasti, A; Rubio-Casillas, A | 1 |
| Albertini, G; Bentea, E; Demuyser, T; Deneyer, L; Massie, A; Smolders, I | 1 |
| Chen, J; Cheng, K; Liao, L; Rao, C; Shi, H; Tang, J; Wang, Z; Wu, Y; Xie, P; Yang, Y; Zhao, M; Zhou, C; Zhou, J; Zhu, D | 1 |
| Mauch, J; Pandit, R; Pitychoutis, PM; Sens, J; Thelen, C | 1 |
| Nowak, G; Pochwat, B; Szewczyk, B | 1 |
| Mazarati, A; Sankar, R | 1 |
| Goel, RK; Singh, T | 1 |
| Gao, SF; Lucassen, PJ; Qi, XR; Swaab, DF; van Wamelen, DJ; Verwer, RW; Zhao, J | 1 |
| Bai, SJ; Cheng, K; Guo, H; Li, J; Liang, ZH; Liao, L; Sun, L; Wang, HY; Wang, W; Xie, P; Yang, DY; Zhang, SX | 1 |
| Bok, P; Chang, S; Edwards, A; Huang, GJ; Sun, CP | 1 |
| Chen, Z; Fan, L; Fu, W; Li, Z; Liu, J; Lu, A; Ou, A; Su, S; Wu, T; Xu, N | 1 |
| Brant, F; de Miranda, AS; de Oliveira Pimentel, PM; Machado, FS; Moraes, MFD; Rachid, MA; Ransohoff, RM; Rezende, GHS; Ribeiro, FM; Rocha, NP; Teixeira, AL; Teixeira, MM; Vieira, ÉLM; Vieira, LB | 1 |
| Haroon, E; Miller, AH | 1 |
| Baranovičová, E; Bittšanský, M; Čierny, D; Hnilicová, P; Kantorová, E; Kurča, E; Nosáľ, V; Poláček, H; Sivák, Š; Zeleňák, K | 1 |
| Kumar, M; Kumar, P | 1 |
| Bamberg, E; Betz, H; Caldwell, JH; Herin, GA; Nagel, G; Scheschonka, A | 1 |
| Banasr, M; Behar, KL; Chowdhury, GM; Duman, RS; Newton, SS; Sanacora, G; Terwilliger, R | 1 |
| Calişkan, M; Gören, MZ; Kaplan, OK; Küçükibrahimoğlu, E; Saygin, MZ; Unsal, C | 1 |
| Sanacora, G; Valentine, GW | 1 |
| Del Rio, J; Elizalde, N; Garcia-Garcia, AL; Harro, J; Matrov, D; Ramírez, MJ; Tordera, RM; Venzala, E; Wojcik, SM | 1 |
| Bolo, N; Jacobson, AM; Kim, JE; Lyoo, IK; Musen, G; Renshaw, PF; Ryan, CM; Simonson, DC; Weinger, K; Yoon, SJ | 1 |
| Antoniou, K; Kokras, N; Papadopoulou-Daifoti, Z; Polissidis, A | 1 |
| Chattarji, S; Diamond, DM; Fuchs, E; Jay, TM; McEwen, BS; Reagan, LP; Svenningsson, P | 1 |
| Bargalló, N; Collado, A; Gómez, E; Rami, L; Salamero, M; Valdés, M; Vázquez, M | 1 |
| Bao, AM; Gao, SF | 1 |
| Almeida, RF; Ganzella, M; Godinho, GF; Saute, JA; Souza, DO; Thomazi, AP; Wofchuk, ST | 1 |
| Sas, K | 1 |
| Chang, RC; Law, AC; Wuwongse, S | 1 |
| Cao, J; Dong, J; Li, P; Li, Y; Min, S; Wei, K | 1 |
| Fang, J; Guo, JY; Li, CY; Lou, JS; Yang, XC; Yang, YX | 1 |
| Cowen, PJ; Mannie, ZN; Near, J; Norbury, R; Taylor, MJ | 1 |
| Aso, E; Del Rio, J; Elizalde, N; Garcia-García, AL; Ramírez, MJ; Segura, V; Tordera, RM; Venzala, E | 1 |
| Charney, DS; Murrough, JW | 1 |
| Takeda, A | 1 |
| An, SC; Wang, MH | 1 |
| Li, MH; Li, YH; Lu, J; Sun, XJ; Wang, X; Ye, JL; Zhang, B; Zhao, JG | 1 |
| Gerhardt, GA; Glaser, PE; Hascup, ER; Hascup, KN; Kehr, J; Mathé, AA; Stephens, ML; Yoshitake, T | 1 |
| Marsden, WN | 1 |
| Biedermann, S; Ende, G; Gass, P; Hoyer, C; Sartorius, A; Vollmayr, B; Weber-Fahr, W; Zheng, L | 1 |
| Dal-Cim, T; Maraschin, M; Rodrigues, AL; Tasca, CI; Zeni, AL; Zomkowski, AD | 1 |
| Binder, EB; Czamara, D; Czisch, M; Heck, A; Hennings, J; Holsboer, F; Kloiber, S; Kohli, MA; Lucae, S; Menke, A; Müller-Myhsok, B; Sämann, P | 1 |
| Horrillo, I; Martisova, E; Meana, JJ; Ortega, JE; Ramírez, MJ; Solas, M; Tordera, RM | 1 |
| An, FL; An, SC | 1 |
| Anand, A; Barkay, G; Ghosh, S; Gunn, AD; Karne, HS; Mathew, SJ; Nurnberger, JI | 1 |
| De Bundel, D; Gómez-Galán, M; Lindskog, M; Smolders, I; Van Eeckhaut, A | 1 |
| Alexander, R; Kanes, S; Lee, CM; McCarthy, DJ; Pathak, S; Sanacora, G; Smith, MA | 1 |
| Chiba, S; Kunugi, H; Ninomiya, M; Numakawa, T; Richards, MC; Wakabayashi, C | 1 |
| Elizalde, N; García-García, AL; Tordera, RM; Venzala, E | 1 |
| Dong, J; Li, P; Liu, C; Liu, D; Liu, XB; Luo, J; Min, S; Wei, K | 1 |
| Alvarsson, A; Arango-Lievano, M; Eriksson, TM; Gerhardt, GA; Greengard, P; Hascup, ER; Hascup, KN; Kaplitt, MG; Kehr, J; Ogren, SO; Stan, TL; Svenningsson, P; Warner-Schmidt, J; Zhang, X | 1 |
| Bora, E; Lubman, DI; MacKenzie, T; Roffel, K; Verdejo-García, A; Vilar-López, R; Yücel, M | 1 |
| Musazzi, L; Popoli, M; Treccani, G | 1 |
| Brealy, J; Edden, RA; John Evans, C; Keedwell, PA; Muthukumaraswamy, SD; Puts, NA; Richardson, H; Shaw, A; Singh, KD | 1 |
| Skolnick, P | 1 |
| Chau, DT; Gonzalez, LE; Harrison, T; Hernandez, L; Hoebel, BG; Moreno, SA; Rada, P; Tucci, S | 1 |
| SIUCHNINSKA, H | 1 |
| Heinz, A; Lieb, K; Pich, M; Schaefer, M; Schwaiger, M | 1 |
| Andin, J; Marcusson, J; Ross, SB; Stenfors, C | 1 |
| Cowen, MS; Djouma, E; Lawrence, AJ | 1 |
| Jezova, D | 1 |
| Palucha, A | 1 |
| Müller, N; Schwarz, MJ | 1 |
| Ferreira, FR; Guimarães, FS; Joca, SR | 1 |
| Ende, G; Henn, FA; Mahlstedt, MM; Sartorius, A; Vollmayr, B | 1 |
| Kasper, S; McEwen, BS | 1 |
| Gao, H; Huang, M; Lei, H; Li, CX; Pan, WJ; Wang, Y; Xiang, Y | 1 |
| Petty, F; Sherman, AD | 1 |
| Beauchemin, V; Debonnel, G; Dennis, T; Lavoie, N; Robichaud, M | 1 |
| Deakin, JF; Law, AJ | 1 |
| McEwen, BS | 1 |
| Bengtsson, F; Grampp, W; Siesjö, BK; Theander, S | 1 |
43 review(s) available for glutamic acid and Depression
| Article | Year |
|---|---|
Ketamine as a Treatment for Anorexia Nervosa: A Narrative Review.
Topics: Anorexia Nervosa; Antidepressive Agents; Brain; Comorbidity; Depression; Glutamic Acid; Humans; Ketamine; Neuronal Plasticity | 2021 |
Guanosine as a promising target for fast-acting antidepressant responses.
Topics: Antidepressive Agents; Depression; Depressive Disorder, Treatment-Resistant; Glutamic Acid; Guanosine; Humans; Ketamine | 2022 |
Repetitive Transcranial Magnetic Stimulation-Associated Changes in Neocortical Metabolites in Major Depression: A Systematic Review.
Topics: Depression; Depressive Disorder, Major; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Neocortex; Prefrontal Cortex; Transcranial Magnetic Stimulation; Treatment Outcome | 2022 |
Topics: Acute Kidney Injury; Adult; Aged; Aortic Dissection; Child; Depression; Glutamate Dehydrogenase; Glutamic Acid; Glutathione; Glutathione Reductase; Glutathione Transferase; Humans; Male; Postoperative Complications; Retrospective Studies; Risk Factors; Schizophrenia; Young Adult | 2022 |
NMDA receptors as therapeutic targets for depression treatment: Evidence from clinical to basic research.
Topics: Animals; Antidepressive Agents; Artificial Intelligence; Depression; Glutamic Acid; Ketamine; Receptors, N-Methyl-D-Aspartate | 2023 |
The roles of neuroinflammation and glutamatergic excitotoxicity in treatment-resistant depression.
Topics: Central Nervous System; Depression; Depressive Disorder, Major; Glutamic Acid; Humans; Neuroinflammatory Diseases | 2023 |
Brain metabolic derangements examined using
Topics: Animals; Aspartic Acid; Brain; Depression; Depressive Disorder, Major; Glutamic Acid; Glutamine; Proton Magnetic Resonance Spectroscopy; Rodentia | 2023 |
The Importance of α-Klotho in Depression and Cognitive Impairment and Its Connection to Glutamate Neurotransmission-An Up-to-Date Review.
Topics: Cognitive Dysfunction; Depression; Depressive Disorder, Major; Glucuronidase; Glutamic Acid; Humans; Synaptic Transmission | 2023 |
Diet's Impact on Post-Traumatic Brain Injury Depression: Exploring Neurodegeneration, Chronic Blood-Brain Barrier Destruction, and Glutamate Neurotoxicity Mechanisms.
Topics: Blood-Brain Barrier; Brain Injuries, Traumatic; Depression; Glutamic Acid; Humans; Quality of Life | 2023 |
An Update on Glutamatergic System in Suicidal Depression and on the Role of Esketamine.
Topics: Administration, Intranasal; Antidepressive Agents; Clinical Trials as Topic; Databases, Factual; Depression; Depressive Disorder, Major; Drug Compounding; Glutamic Acid; Humans; Ketamine; Receptors, N-Methyl-D-Aspartate; Suicide Prevention; Synaptic Transmission; Time Factors; Treatment Outcome; United States; United States Food and Drug Administration | 2020 |
Memantine in neurological disorders - schizophrenia and depression.
Topics: Alzheimer Disease; Antidepressive Agents; Antipsychotic Agents; Clinical Trials as Topic; Depression; Drug Repositioning; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Memantine; N-Methylaspartate; Neuronal Plasticity; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Serotonin 5-HT3 Receptor Antagonists | 2021 |
Interplay between Brain BDNF and Glutamatergic Systems: A Brief State of the Evidence and Association with the Pathogenesis of Depression.
Topics: Animals; Brain; Brain-Derived Neurotrophic Factor; Depression; Glutamic Acid; Humans; Neuronal Plasticity | 2017 |
Synaptic Plasticity in the Nucleus Accumbens: Lessons Learned from Experience.
Topics: Animals; Anxiety; Behavior, Addictive; Depression; Endocannabinoids; Feeding Behavior; Glutamic Acid; Humans; Learning; Motivation; Neuroglia; Neuronal Plasticity; Nucleus Accumbens; Opioid Peptides; Receptors, AMPA; Receptors, Cannabinoid; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid; Reward; Serotonin | 2018 |
Circadian modulation of neuroplasticity by melatonin: a target in the treatment of depression.
Topics: Animals; Circadian Rhythm; Depression; Glutamic Acid; Hippocampus; Humans; Melatonin; Neuronal Plasticity | 2018 |
The neurobiology of depression, ketamine and rapid-acting antidepressants: Is it glutamate inhibition or activation?
Topics: Animals; Antidepressive Agents; Biomarkers; Depression; Disease Models, Animal; Drug Development; Glutamic Acid; Humans; Ketamine; Synaptic Transmission | 2018 |
Crosstalk Between Inflammation and Glutamate System in Depression: Signaling Pathway and Molecular Biomarkers for Ketamine's Antidepressant Effect.
Topics: Animals; Antidepressive Agents; Biomarkers; Depression; Glutamic Acid; Humans; Inflammation; Ketamine; Signal Transduction | 2019 |
Depression and schizophrenia viewed from the perspective of amino acidergic neurotransmission: Antipodes of psychiatric disorders.
Topics: Animals; Antipsychotic Agents; Depression; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Receptors, GABA; Receptors, Ionotropic Glutamate; Receptors, Metabotropic Glutamate; Schizophrenia; Synaptic Transmission | 2019 |
Glutamatergic neurometabolite levels in major depressive disorder: a systematic review and meta-analysis of proton magnetic resonance spectroscopy studies.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Depression; Depressive Disorder, Major; Female; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Proton Magnetic Resonance Spectroscopy; Synaptic Transmission | 2019 |
Novel Pathways in the Treatment of Major Depression: Focus on the Glutamatergic System.
Topics: Depression; Depressive Disorder, Major; Excitatory Amino Acid Agents; Glutamic Acid; Humans; Ketamine; Synaptic Transmission | 2019 |
Neurobiology of rapid-acting antidepressants: convergent effects on GluA1-synaptic function.
Topics: Animals; Antidepressive Agents; Depression; Depressive Disorder, Major; Glutamic Acid; Humans; Ketamine; Neurobiology; Neurogenesis; Neurons; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Synapses; Synaptic Transmission | 2019 |
Ketamine as a fast acting antidepressant: current knowledge and open questions.
Topics: Animals; Antidepressive Agents; Clinical Trials as Topic; Depression; Drug Evaluation, Preclinical; Glutamic Acid; Humans; Ketamine | 2013 |
Rapid-acting glutamatergic antidepressants: the path to ketamine and beyond.
Topics: Animals; Antidepressive Agents; Depression; Glutamic Acid; Humans; Ketamine | 2013 |
Serotonergic modulation of glutamate neurotransmission as a strategy for treating depression and cognitive dysfunction.
Topics: Animals; Cognition Disorders; Depression; Glutamic Acid; Humans; Serotonin; Serotonin Agents; Synaptic Transmission | 2014 |
Multifunctional aspects of allopregnanolone in stress and related disorders.
Topics: Anxiety; Brain-Derived Neurotrophic Factor; Calcium Channels; Depression; Dopamine; Glutamic Acid; Humans; Oxytocin; Pregnanolone; Receptors, GABA-A; Stress, Psychological | 2014 |
GPR39 Zn(2+)-sensing receptor: a new target in antidepressant development?
Topics: Animals; Antidepressive Agents; Brain; Brain-Derived Neurotrophic Factor; Depression; Depressive Disorder; Glutamic Acid; Humans; Learning; Memory; Molecular Targeted Therapy; Mood Disorders; Neuroprotective Agents; Receptors, G-Protein-Coupled; Signal Transduction; Up-Regulation; Weight Gain; Weight Loss; Zinc | 2015 |
Zinc in the Glutamatergic Theory of Depression.
Topics: Animals; Antidepressive Agents; Depression; Depressive Disorder, Major; Glutamic Acid; Humans; Receptors, N-Methyl-D-Aspartate; Zinc | 2015 |
Emerging treatment mechanisms for depression: focus on glutamate and synaptic plasticity.
Topics: Animals; Antidepressive Agents; Depression; Depressive Disorder, Major; Excitatory Amino Acid Agents; GABA-A Receptor Agonists; Glutamic Acid; Humans; Ketamine; Muscarinic Antagonists; Neuronal Plasticity; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Scopolamine; Stress, Psychological | 2016 |
The dose makes the poison: from glutamate-mediated neurogenesis to neuronal atrophy and depression.
Topics: Animals; Depression; Glutamic Acid; Humans; Neurogenesis; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 2016 |
Common Mechanisms Underlying Epileptogenesis and the Comorbidities of Epilepsy.
Topics: Animals; Brain; Comorbidity; Depression; Epilepsy; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Hypothalamo-Hypophyseal System; Inflammation; Magnetic Resonance Imaging; Neurotransmitter Agents; Quality of Life; Serotonin | 2016 |
Inflammation Effects on Brain Glutamate in Depression: Mechanistic Considerations and Treatment Implications.
Topics: Animals; Depression; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Inflammation | 2017 |
The neurobiological properties of tianeptine (Stablon): from monoamine hypothesis to glutamatergic modulation.
Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Anxiety; Biogenic Monoamines; Brain; Cognition Disorders; Depression; Disease Models, Animal; Glutamic Acid; Humans; Neuronal Plasticity; Stress, Psychological; Thiazepines | 2010 |
Corticotropin-releasing hormone, glutamate, and γ-aminobutyric acid in depression.
Topics: Corticotropin-Releasing Hormone; Depression; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Hypothalamo-Hypophyseal System; Pituitary-Adrenal System | 2011 |
The putative neurodegenerative links between depression and Alzheimer's disease.
Topics: Acetylcholine; Alzheimer Disease; Animals; Depression; Glutamic Acid; Humans; Nerve Degeneration; Neurons | 2010 |
Zinc signaling in the hippocampus and its relation to pathogenesis of depression.
Topics: Aging; Animals; Depression; Glutamic Acid; Hippocampus; Homeostasis; Humans; Hypothalamo-Hypophyseal System; Long-Term Potentiation; Mossy Fibers, Hippocampal; Signal Transduction; Stress, Physiological; Zinc | 2011 |
Modulation of glutamate receptors: strategies for the development of novel antidepressants.
Topics: Animals; Antidepressive Agents; Depression; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Motor Activity; Receptors, Glutamate; Sulfonamides; Synaptic Transmission; Thiophenes | 2002 |
Neurotransmitter changes by interferon-alpha and therapeutic implications.
Topics: Animals; Confusion; Depression; Dopamine; Glutamic Acid; Humans; Interferon-alpha; Narcotic Antagonists; Neurotransmitter Agents; Norepinephrine; Paranoid Disorders; Psychoses, Substance-Induced; Receptors, Opioid; Selective Serotonin Reuptake Inhibitors; Serotonin; Suicide | 2003 |
Control of ACTH secretion by excitatory amino acids: functional significance and clinical implications.
Topics: Adaptation, Physiological; Adrenocorticotropic Hormone; Animals; Antidepressive Agents; Depression; Excitatory Amino Acids; Glutamic Acid; Humans; Hypothalamo-Hypophyseal System; Pituitary-Adrenal System; Rats; Stress, Psychological | 2005 |
Are compounds acting at metabotropic glutamate receptors the answer to treating depression?
Topics: Allosteric Regulation; Animals; Antidepressive Agents; Depression; Depressive Disorder; Drug Design; Drug Evaluation, Preclinical; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Ligands; Mice; Rats; Receptors, Glutamate; Receptors, Metabotropic Glutamate | 2006 |
The immune-mediated alteration of serotonin and glutamate: towards an integrated view of depression.
Topics: Animals; Depression; Glutamic Acid; Humans; Hypothalamo-Hypophyseal System; Immune System; Pituitary-Adrenal System; Serotonin | 2007 |
Modulation of stress consequences by hippocampal monoaminergic, glutamatergic and nitrergic neurotransmitter systems.
Topics: Adaptation, Psychological; Affect; Animals; Antidepressive Agents; Biogenic Monoamines; Depression; Dopamine; Glutamic Acid; Hippocampus; Humans; Neurons; Nitrergic Neurons; Nitric Oxide; Norepinephrine; Serotonin; Stress, Psychological | 2007 |
Neurobiological and clinical effects of the antidepressant tianeptine.
Topics: Animals; Antidepressive Agents, Tricyclic; Anxiety; Brain; Cognition; Depression; Glutamic Acid; Humans; Memory; Synapses; Thiazepines | 2008 |
Plasticity of the hippocampus: adaptation to chronic stress and allostatic load.
Topics: Adaptation, Physiological; Adrenal Cortex; Aging; Animals; Atrophy; Brain Ischemia; Chronic Disease; Circadian Rhythm; Dendrites; Dentate Gyrus; Depression; Estrogens; Female; Glucocorticoids; Glutamic Acid; Hippocampus; Humans; Hypothalamo-Hypophyseal System; Male; Memory Disorders; Models, Animal; Neuralgia; Neurons; Pain; Pituitary-Adrenal System; Rats; Restraint, Physical; Seizures; Stress Disorders, Post-Traumatic; Stress, Physiological; Tumor Necrosis Factor-alpha | 2001 |
Calcium, excitotoxins, and neuronal death in the brain.
Topics: Animals; Brain; Calcium; Calcium Channels; Cell Survival; Depression; Glutamates; Glutamic Acid; Homeostasis; Humans; Hypoglycemia; Hypoxia; Ischemia; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1989 |
3 trial(s) available for glutamic acid and Depression
| Article | Year |
|---|---|
N-acetylcysteine for depression and glutamate changes in the left prefrontal cortex in adolescents and young adults at risk for bipolar disorder: A pilot study.
Topics: Acetylcysteine; Adolescent; Bipolar Disorder; Depression; Glutamic Acid; Humans; Pilot Projects; Prefrontal Cortex; Young Adult | 2022 |
Early antidepressant effect of memantine during augmentation of lamotrigine inadequate response in bipolar depression: a double-blind, randomized, placebo-controlled trial.
Topics: Adult; Antidepressive Agents; Antimanic Agents; Bipolar Disorder; Depression; Dopamine Agents; Double-Blind Method; Drug Therapy, Combination; Female; Glutamic Acid; Humans; Lamotrigine; Male; Memantine; Middle Aged; Pilot Projects; Treatment Outcome; Triazines | 2012 |
Cingulate biochemistry in heroin users on substitution pharmacotherapy.
Topics: Adult; Aspartic Acid; Buprenorphine; Depression; Dose-Response Relationship, Drug; Female; Functional Neuroimaging; Glutamic Acid; Glutamine; Gyrus Cinguli; Heroin Dependence; Humans; Inositol; Male; Methadone; Opiate Substitution Treatment | 2013 |
197 other study(ies) available for glutamic acid and Depression
| Article | Year |
|---|---|
Editorial for "Glutamate Chemical Exchange Saturation Transfer Imaging and Functional Alterations of Hippocampus in Rat Depression Model: A Pilot Study".
Topics: Animals; Depression; Glutamic Acid; Hippocampus; Magnetic Resonance Imaging; Pilot Projects; Rats | 2021 |
The role of glutamate in a multifactorial scenario of Alzheimer' disease associated with depression and poor sleep.
Topics: Alzheimer Disease; Depression; Glutamic Acid; Humans; Sleep; Sleep Initiation and Maintenance Disorders | 2021 |
Activation of parabrachial nucleus - ventral tegmental area pathway underlies the comorbid depression in chronic neuropathic pain in mice.
Topics: Action Potentials; Animals; Behavior, Animal; Chronic Pain; Depression; Disease Models, Animal; Dopamine Plasma Membrane Transport Proteins; Dopaminergic Neurons; Female; Glutamic Acid; Male; Mice, Inbred C57BL; Mice, Transgenic; Neural Pathways; Parabrachial Nucleus; Trigeminal Caudal Nucleus; Trigeminal Neuralgia; Ventral Tegmental Area; Vesicular Glutamate Transport Protein 2 | 2021 |
Amygdalar κ-opioid receptor-dependent upregulating glutamate transporter 1 mediates depressive-like behaviors of opioid abstinence.
Topics: Amygdala; Animals; Behavior, Animal; Depression; Disease Models, Animal; Dynorphins; Excitatory Postsynaptic Potentials; Glucose Transporter Type 1; Glutamic Acid; Male; Mice, Inbred C57BL; Mice, Knockout; Morphine; Neural Pathways; Nucleus Accumbens; p38 Mitogen-Activated Protein Kinases; Receptors, Opioid, kappa; Signal Transduction; Substance Withdrawal Syndrome | 2021 |
Pigment epithelium-derived factor may induce antidepressant phenotypes in mice by the prefrontal cortex.
Topics: Adult; Animals; Depression; Down-Regulation; Eye Proteins; Female; Glutamic Acid; Humans; Male; Mice; Mice, Inbred C57BL; Nerve Growth Factors; Phenotype; Prefrontal Cortex; Serpins; Stress, Psychological; Tryptophan | 2022 |
Periaqueductal gray is required for controlling chronic stress-induced depression-like behavior.
Topics: Animals; Antidepressive Agents; Depression; Electrophysiological Phenomena; Excitatory Postsynaptic Potentials; Female; Glutamic Acid; Male; Mice; Mice, Inbred C57BL; Periaqueductal Gray; Stress, Psychological; Synaptic Transmission | 2022 |
Develop a stepwise integrated method to screen biomarkers of Baihe-Dihuang Tang on the treatment of depression in rats applying with composition screened, untargeted, and targeted metabolomics analysis.
Topics: Animals; Antidepressive Agents; Biomarkers; Depression; Drugs, Chinese Herbal; Glutamic Acid; Metabolomics; Rats | 2022 |
Music alleviates pain perception in depression mouse models by promoting the release of glutamate in the hippocampus of mice to act on GRIK5.
Topics: Animals; Depression; Glutamic Acid; Hippocampus; Mice; Music; N-Methylaspartate; Pain; Pain Perception; Serotonin | 2022 |
Dexmedetomidine improves excessive extracellular glutamate-induced synaptic depression (BRAINRES-D-21-00941).
Topics: Animals; Depression; Dexmedetomidine; Dobutamine; Glutamic Acid; Hippocampus; Isoproterenol; Rats; Receptors, Adrenergic; Synaptic Transmission | 2022 |
Possible involvement of NO-cGMP signaling in the antidepressant like Effect of Amantadine in mice.
Topics: Amantadine; Animals; Antidepressive Agents; Cyclic GMP; Depression; Glutamic Acid; Hindlimb Suspension; Mice; Nitric Oxide; Nitrites; Serotonin; Swimming | 2022 |
Pupil dilation during negative prediction errors is related to brain choline concentration and depressive symptoms in adolescents.
Topics: Adolescent; Biomarkers; Brain; Choline; Cholinergic Agents; Depression; gamma-Aminobutyric Acid; Glutamic Acid; Gyrus Cinguli; Humans; Pilot Projects; Pupil | 2023 |
Fast antidepressant action of ketamine in mouse models requires normal VGLUT1 levels from prefrontal cortex neurons.
Topics: Anhedonia; Animals; Antidepressive Agents; Brain-Derived Neurotrophic Factor; Depression; Disease Models, Animal; Glutamic Acid; Ketamine; Mice; Neurons; Prefrontal Cortex; Reboxetine; Vesicular Glutamate Transport Protein 1 | 2023 |
Involvement of kynurenine pathway between inflammation and glutamate in the underlying etiopathology of CUMS-induced depression mouse model.
Topics: Animals; Depression; Disease Models, Animal; Glutamic Acid; Indoleamine-Pyrrole 2,3,-Dioxygenase; Inflammation; Kynurenine; Mice; Tryptophan | 2022 |
Deficiency of astrocyte CysLT
Topics: Animals; Astrocytes; Depression; Glutamic Acid; Hippocampus; Mice; NF-kappa B; Receptors, Leukotriene; Stress, Psychological; Sucrose; Synaptic Transmission | 2022 |
Identification of proline, 1-pyrroline-5-carboxylate and glutamic acid as biomarkers of depression reflecting brain metabolism using carboxylomics, a new metabolomics method.
Topics: Animals; Biomarkers; Brain; Depression; Glutamic Acid; Humans; Metabolomics; Proline; Rats | 2023 |
Altered neurometabolite levels in the brains of patients with depression: A systematic analysis of magnetic resonance spectroscopy studies.
Topics: Aspartic Acid; Brain; Choline; Depression; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; Proton Magnetic Resonance Spectroscopy; Reproducibility of Results | 2023 |
Pharmacological Profile of MP-101, a Novel Non-racemic Mixture of R- and S-dimiracetam with Increased Potency in Rat Models of Cognition, Depression and Neuropathic Pain.
Topics: Animals; Cognition; D-Aspartic Acid; Depression; Glutamic Acid; N-Methylaspartate; Neuralgia; Rats | 2022 |
The Utility of Amino Acid Metabolites in the Diagnosis of Major Depressive Disorder and Correlations with Depression Severity.
Topics: Amino Acids; Aspartic Acid; Biomarkers; Depression; Depressive Disorder, Major; Glutamic Acid; Glycine; Humans; Phenylalanine | 2023 |
Loss of sodium leak channel (NALCN) in the ventral dentate gyrus impairs neuronal activity of the glutamatergic neurons for inflammation-induced depression in male mice.
Topics: Animals; Dentate Gyrus; Depression; Glutamic Acid; Inflammation; Ion Channels; Lipopolysaccharides; Male; Membrane Proteins; Mice; Neurons; Sodium | 2023 |
GluCEST Imaging and Structural Alterations of the Bilateral Hippocampus in First-Episode and Early-Onset Major Depression Disorder.
Topics: Cross-Sectional Studies; Depression; Depressive Disorder, Major; Female; Glutamic Acid; Hippocampus; Humans; Magnetic Resonance Imaging; Male | 2023 |
NMDA receptor-mediated modulation on glutamine synthetase and glial glutamate transporter GLT-1 is involved in the antidepressant-like and neuroprotective effects of guanosine.
Topics: Amino Acid Transport System X-AG; Animals; Antidepressive Agents; Depression; Excitatory Amino Acid Transporter 2; Glutamate-Ammonia Ligase; Glutamic Acid; Guanosine; Hippocampus; Ketamine; Mice; Molecular Docking Simulation; Neuroprotective Agents; Receptors, N-Methyl-D-Aspartate | 2023 |
Glutamate shall not pass: a mechanistic role for astrocytic O-GlcNAc transferase in stress and depression.
Topics: Acetylglucosamine; Animals; Astrocytes; Depression; Depressive Disorder, Major; Glucose; Glutamic Acid; Mice; N-Acetylglucosaminyltransferases; Protein Processing, Post-Translational | 2023 |
Plasma metabolomics and network pharmacology identified glutamate, glutamine, and arginine as biomarkers of depression under Shuganjieyu capsule treatment.
Topics: Animals; Arginine; Biomarkers; Depression; Drugs, Chinese Herbal; Glutamic Acid; Glutamine; Metabolomics; Network Pharmacology | 2023 |
Yueju volatile oil plays an integral role in the antidepressant effect by up-regulating ERK/AKT-mediated GLT-1 expression to clear glutamate.
Topics: Animals; Antidepressive Agents; Depression; Disease Models, Animal; Glutamic Acid; Hippocampus; Mice; Molecular Structure; Oils, Volatile; Proto-Oncogene Proteins c-akt; Stress, Psychological | 2023 |
Inhibition of xCT by sulfasalazine alleviates the depression-like behavior of adult male mice subjected to maternal separation stress.
Topics: Animals; Depression; Glutamic Acid; Hippocampus; Male; Maternal Deprivation; Mice; Prefrontal Cortex; Stress, Psychological; Sulfasalazine | 2023 |
The role of neurotransmitters in mediating the relationship between brain alterations and depressive symptoms in patients with inflammatory bowel disease.
Topics: Brain; Depression; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Inflammatory Bowel Diseases; Magnetic Resonance Imaging; Neurotransmitter Agents | 2023 |
Xiaoyaosan exerts antidepressant-like effects by regulating the functions of astrocytes and EAATs in the prefrontal cortex of mice.
Topics: Animals; Antidepressive Agents; Astrocytes; Behavior, Animal; Depression; Disease Models, Animal; Drugs, Chinese Herbal; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Glial Fibrillary Acidic Protein; Glutamic Acid; Humans; Male; Mice; Mice, Inbred C57BL; Prefrontal Cortex | 2019 |
Mechanisms of action of the ketogenic diet in depression.
Topics: Depression; Depressive Disorder; Diet, Ketogenic; Glutamic Acid; Humans; Mood Disorders | 2019 |
Electrical high frequency stimulation of the nucleus accumbens shell does not modulate depressive-like behavior in rats.
Topics: Animals; Behavior, Animal; Deep Brain Stimulation; Depression; Disease Models, Animal; gamma-Aminobutyric Acid; Glutamic Acid; Male; Microdialysis; Motor Activity; Nucleus Accumbens; Rats; Rats, Wistar | 2020 |
Calcium Salt of N-(5-Hydroxynicotinoyl)-L-Glutamic Acid Weakens Depressive-Like Behavior and Parkinsonian Syndrome in Experiment on Rodents.
Topics: Animals; Antidepressive Agents; Calcium; Catalepsy; Depression; Glutamic Acid; Haloperidol; Male; Mice; Mice, Inbred C57BL; Parkinsonian Disorders | 2019 |
Studies on the potential link between antidepressant effect of Xiaoyao San and its pharmacological activity of hepatoprotection based on multi-platform metabolomics.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Depression; Disease Models, Animal; Drugs, Chinese Herbal; Glutamate-Ammonia Ligase; Glutamic Acid; Glutaminase; Glutamine; Humans; Liver; Male; Medicine, Chinese Traditional; Metabolomics; Protective Agents; Proton Magnetic Resonance Spectroscopy; Rats | 2020 |
Coniferyl ferulate exerts antidepressant effect via inhibiting the activation of NMDAR-CaMKII-MAPKs and mitochondrial apoptotic pathways.
Topics: Animals; Antidepressive Agents; Apoptosis; Behavior, Animal; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Coumaric Acids; Depression; Glutamic Acid; Mice; Mitochondria; Mitogen-Activated Protein Kinases; Neuroprotective Agents; Neurotoxicity Syndromes; PC12 Cells; Rats; Receptors, N-Methyl-D-Aspartate | 2020 |
The glutamatergic system and astrocytic impairment in rat hippocampus: a comparative study of underlying etiology and pathophysiology of depression.
Topics: Animals; Apoptosis; Astrocytes; Behavior, Animal; Depression; Disease Models, Animal; Glutamic Acid; Hippocampus; Male; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Stress, Psychological | 2019 |
Dietary intake of polyunsaturated fatty acids alleviates cognition deficits and depression-like behaviour via cannabinoid system in sleep deprivation rats.
Topics: Affect; alpha-Linolenic Acid; Animals; Behavior, Animal; Cognition; Cognitive Dysfunction; Depression; Diet; Endocannabinoids; Fatty Acids, Unsaturated; Glutamic Acid; Hippocampus; Linoleic Acid; Male; Oleic Acid; Paeonia; Patch-Clamp Techniques; Plant Oils; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Sleep Deprivation; Synaptic Transmission | 2020 |
Glutamatergic and GABA-ergic abnormalities in First-episode depression. A 1-year follow-up 1H-MR spectroscopic study.
Topics: Depression; Depressive Disorder, Major; Follow-Up Studies; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; Prefrontal Cortex; Proton Magnetic Resonance Spectroscopy | 2020 |
Impaired neuronal and astroglial metabolic activity in chronic unpredictable mild stress model of depression: Reversal of behavioral and metabolic deficit with lanicemine.
Topics: Animals; Astrocytes; Depression; Disease Models, Animal; Glutamic Acid; Male; Mice, Inbred C57BL; Neurons; Neurotransmitter Agents; Phenethylamines; Pyridines; Stress, Psychological; Sucrose | 2020 |
Glutamatergic pathway in depressive-like behavior associated with pentylenetetrazole rat model of epilepsy with history of prolonged febrile seizures.
Topics: Amygdala; Animals; Brain-Derived Neurotrophic Factor; Depression; Epilepsy; Excitatory Amino Acid Transporter 1; Glutamate Synthase; Glutamic Acid; Hippocampus; Male; Pentylenetetrazole; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Seizures, Febrile | 2020 |
Ablation of olfactory bulb glutamatergic neurons induces depressive-like behaviors and sleep disturbances in mice.
Topics: Ablation Techniques; Animals; Depression; Excitatory Amino Acid Agonists; Glutamic Acid; Ibotenic Acid; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neurons; Olfactory Bulb; Random Allocation; Sleep; Sleep Wake Disorders | 2020 |
An early increase in glutamate is critical for the development of depression-like behavior in a chronic restraint stress (CRS) model.
Topics: Animals; Antidepressive Agents; Biomarkers; Chronic Disease; Depression; Glutamic Acid; Male; Mice; Mice, Inbred C57BL; Neurons; Restraint, Physical; Stress, Psychological | 2020 |
Antidepressant-Like Effects of CX717, a Positive Allosteric Modulator of AMPA Receptors.
Topics: Animals; Antidepressive Agents; Brain-Derived Neurotrophic Factor; Cell-Penetrating Peptides; Depression; Glutamic Acid; Isoxazoles; Male; Rats, Sprague-Dawley; Receptors, AMPA; Serotonin | 2020 |
Glial glutamate transporter GLT-1 determines susceptibility to spreading depression in the mouse cerebral cortex.
Topics: Animals; Cerebral Cortex; Depression; Excitatory Amino Acid Transporter 2; Glutamic Acid; Mice | 2020 |
Topics: Adult; Depression; Depressive Disorder, Major; gamma-Aminobutyric Acid; Glutamic Acid; Gyrus Cinguli; Humans; Proton Magnetic Resonance Spectroscopy; Sleep; Sleep Initiation and Maintenance Disorders | 2020 |
Low corticosterone levels attenuate late life depression and enhance glutamatergic neurotransmission in female rats.
Topics: Animals; Astrocytes; Corticosterone; Depression; Excitatory Amino Acid Transporter 2; Female; Glutamic Acid; Glutamine; Hippocampus; Neurons; Rats, Sprague-Dawley; Synaptic Transmission; Synaptosomes | 2021 |
Dicaffeoylquinic acids alleviate memory loss via reduction of oxidative stress in stress-hormone-induced depressive mice.
Topics: Animals; Antidepressive Agents; Antioxidants; Astrocytes; Behavior, Animal; Cells, Cultured; Corticosterone; Depression; Disease Models, Animal; Glutamic Acid; Hippocampus; Male; Memory; Memory Disorders; Mice, Inbred ICR; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Neurons; Oxidative Stress; Quinic Acid; Reactive Oxygen Species; Synaptic Transmission | 2020 |
Electroacupuncture Ameliorates CUMS-induced Depression-like Behavior: Involvement of the Glutamatergic System and Apoptosis in Rats.
Topics: Animals; Antidepressive Agents; Apoptosis; Behavior, Animal; Chronic Disease; Depression; Disease Models, Animal; Electroacupuncture; Glutamic Acid; Hippocampus; Male; Rats; Rats, Sprague-Dawley | 2021 |
Neurotransmitters and Neurometabolites in Late-Life Depression: A Preliminary Magnetic Resonance Spectroscopy Study at 7T.
Topics: Aspartic Acid; Creatine; Depression; Depressive Disorder, Major; Glutamic Acid; Gyrus Cinguli; Humans; Infant; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Neurotransmitter Agents; Proton Magnetic Resonance Spectroscopy | 2021 |
Early Life Stress Increases Brain Glutamate and Induces Neurobehavioral Manifestations in Rats.
Topics: Animals; Behavior, Animal; Brain; Depression; Glutamic Acid; Glutamine; Proton Magnetic Resonance Spectroscopy; Rats; Rats, Sprague-Dawley; Stress, Psychological | 2020 |
Alterations of neurotransmitters and related metabolites in the habenula from CUMS-susceptible and -resilient rats.
Topics: Animals; Depression; Disease Susceptibility; Dopamine; gamma-Aminobutyric Acid; Glutamic Acid; Habenula; Male; Neurotransmitter Agents; Rats; Rats, Sprague-Dawley; Stress, Psychological | 2021 |
2-Pentadecyl-2-oxazoline ameliorates memory impairment and depression-like behaviour in neuropathic mice: possible role of adrenergic alpha2- and H3 histamine autoreceptors.
Topics: Amino Acid Sequence; Animals; Anxiety; Behavior, Animal; Chlorocebus aethiops; Cognition; COS Cells; Dentate Gyrus; Depression; Entorhinal Cortex; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Hyperalgesia; Locus Coeruleus; Long-Term Potentiation; Male; Memory Disorders; Mice, Inbred C57BL; Neuralgia; Norepinephrine; Oxazoles; Receptors, Adrenergic, alpha-2; Receptors, Histamine H3; Structural Homology, Protein | 2021 |
Hyperforin alleviates the psychiatric disorders of adult rats suffered from early maternal separation via activating autophagy.
Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Autophagy; Beclin-1; Depression; Disks Large Homolog 4 Protein; Female; Glutamic Acid; Hippocampus; Male; Maternal Deprivation; Phloroglucinol; Rats; Rats, Wistar; Receptor, Notch1; Receptors, N-Methyl-D-Aspartate; Synaptophysin; Terpenes | 2021 |
A preliminary study of the association of increased anterior cingulate gamma-aminobutyric acid with remission of depression after ketamine administration.
Topics: Depression; Depressive Disorder, Treatment-Resistant; gamma-Aminobutyric Acid; Glutamic Acid; Gyrus Cinguli; Humans; Ketamine | 2021 |
Psychological symptoms and salivary inflammatory biomarkers in patients with dentofacial deformities: a case-control study.
Topics: Adolescent; Adult; Anxiety; Biomarkers; Case-Control Studies; Dentofacial Deformities; Depression; Female; Glutamic Acid; Humans; Interleukin-1beta; Male; Middle Aged; Orthognathic Surgical Procedures; Personal Satisfaction; Quality of Life; Saliva; Self Concept; Stress, Psychological; Surveys and Questionnaires; Young Adult | 2021 |
Sublingual AKBA Exerts Antidepressant Effects in the Aβ-Treated Mouse Model.
Topics: Amyloid beta-Peptides; Animals; Antidepressive Agents; Biomarkers; Depression; Disease Models, Animal; Glial Fibrillary Acidic Protein; Glutamic Acid; Kynurenine; Male; Mice; Treatment Outcome; Triterpenes | 2021 |
Involvement of Scratch2 in GalR1-mediated depression-like behaviors in the rat ventral periaqueductal gray.
Topics: Animals; Behavior, Animal; Depression; E-Box Elements; GABAergic Neurons; Gene Expression Regulation; Glutamic Acid; PC12 Cells; Periaqueductal Gray; Promoter Regions, Genetic; Protein Binding; Rats; Receptor, Galanin, Type 1; Stress, Psychological; Transcription Factors; Transcription Initiation Site | 2021 |
Downregulation of astroglial glutamate transporter GLT-1 in the lateral habenula is associated with depressive-like behaviors in a rat model of Parkinson's disease.
Topics: Animals; Astrocytes; Depression; Disease Models, Animal; Down-Regulation; Excitatory Amino Acid Transporter 2; Glutamic Acid; Habenula; Oxidopamine; Parkinsonian Disorders; Pars Compacta; Rats; Substantia Nigra; Thalamus; Ventral Tegmental Area | 2021 |
Neuropeptide-S affects cognitive impairment and depression-like behavior on MPTP induced experimental mouse model of Parkinson’s disease
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Cognition; Depression; Disease Models, Animal; Dopamine; Glutamic Acid; Glutamine; Mice; Mice, Inbred C57BL; Neuropeptides; Neuroprotective Agents; Parkinson Disease, Secondary | 2021 |
Glutamate Chemical Exchange Saturation Transfer Imaging and Functional Alterations of Hippocampus in Rat Depression Model: A Pilot Study.
Topics: Animals; Brain; Brain Mapping; Depression; Glutamic Acid; Hippocampus; Magnetic Resonance Imaging; Male; Pilot Projects; Prospective Studies; Rats; Rats, Sprague-Dawley | 2021 |
The role of SIRT1 in the basolateral amygdala in depression-like behaviors in mice.
Topics: Amygdala; Animals; Depression; Glutamic Acid; Male; Mice; Mice, Inbred C57BL; Neurons; Sirtuin 1 | 2021 |
Polymorphisms in the IL1-b gene are associated with increased Glu and Glx levels in treatment-resistant depression.
Topics: Depression; Glutamic Acid; Glutamine; Humans; Interleukin-1beta; Polymorphism, Genetic | 2021 |
Prospective study on the association between serum amino acid profiles and depressive symptoms among the Japanese working population.
Topics: Adult; Aged; Arginine; Chromatography, Liquid; Depression; Employment; Female; Glutamic Acid; Health Surveys; Humans; Japan; Logistic Models; Male; Mass Spectrometry; Middle Aged; Odds Ratio; Prospective Studies; Tryptophan | 2021 |
mTOR Knockdown in the Infralimbic Cortex Evokes A Depressive-like State in Mouse.
Topics: Animals; Brain-Derived Neurotrophic Factor; Depression; Disease Models, Animal; Dorsal Raphe Nucleus; Gene Knockdown Techniques; Glutamic Acid; Hindlimb Suspension; Male; Mice; Prefrontal Cortex; Serotonin; Swimming; TOR Serine-Threonine Kinases | 2021 |
Ketamine-induced reduction in mGluR5 availability is associated with an antidepressant response: an [
Topics: Adult; Antidepressive Agents; Brain; Carbon Radioisotopes; Case-Control Studies; Depression; Depressive Disorder, Major; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Humans; Ketamine; Male; Positron-Emission Tomography; Receptor, Metabotropic Glutamate 5 | 2018 |
Uncoupling DAPK1 from NMDA receptor GluN2B subunit exerts rapid antidepressant-like effects.
Topics: Animals; Antidepressive Agents; Chronic Disease; Death-Associated Protein Kinases; Depression; Depressive Disorder; Disease Models, Animal; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Phosphorylation; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Stress, Psychological | 2018 |
Impact of High-Fat Diet and Early Stress on Depressive-Like Behavior and Hippocampal Plasticity in Adult Male Rats.
Topics: Animals; Behavior, Animal; Biomarkers; Depression; Diet, High-Fat; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Male; Models, Biological; Neuronal Plasticity; Rats, Wistar; Receptors, Glucocorticoid; Sexual Maturation; Social Isolation; Stress, Psychological; Sucrose | 2018 |
Improvement of Antioxidant Defences and Mood Status by Oral GABA Tea Administration in a Mouse Model of Post-Stroke Depression.
Topics: Affect; Animals; Depression; Disease Models, Animal; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutamine; Lipid Peroxidation; Male; Mice; Mice, Inbred BALB C; Plant Extracts; Polyphenols; Reproducibility of Results; Stroke; Tea | 2017 |
The combination of plasma glutamate and physical impairment after acute stroke as a potential indicator for the early-onset post-stroke depression.
Topics: Acute Disease; Aged; Brain Ischemia; Depression; Female; Glutamic Acid; Humans; Male; Prognosis; Stroke | 2017 |
JIEYUANSHEN DECOCTION EXERTS ANTIDEPRESSANT EFFECTS ON DEPRESSIVE RAT MODEL VIA REGULATING HPA AXIS AND THE LEVEL OF AMINO ACIDS NEUROTRANSMITTER.
Topics: Adrenocorticotropic Hormone; Animals; Antidepressive Agents; Chronic Disease; Corticosterone; Corticotropin-Releasing Hormone; Depression; Depressive Disorder; Disease Models, Animal; Drugs, Chinese Herbal; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Hypothalamo-Hypophyseal System; Magnoliopsida; Male; Neurotransmitter Agents; Phytotherapy; Pituitary-Adrenal System; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Stress, Psychological | 2017 |
Developmental exposure to glyphosate-based herbicide and depressive-like behavior in adult offspring: Implication of glutamate excitotoxicity and oxidative stress.
Topics: Acetylcholinesterase; Age Factors; Animals; Astrocytes; Behavior, Animal; Binding Sites; Cholinergic Fibers; Depression; Female; Gestational Age; Glutamic Acid; Glycine; Glyphosate; GPI-Linked Proteins; Herbicides; Hippocampus; Male; Mitogen-Activated Protein Kinases; Molecular Docking Simulation; Molecular Structure; Motor Activity; Neurotoxicity Syndromes; NF-kappa B; Oxidative Stress; Pregnancy; Prenatal Exposure Delayed Effects; Protein Binding; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; S100 Calcium Binding Protein beta Subunit; Structure-Activity Relationship; Synaptic Transmission | 2017 |
Increased Glutamate in Somatosensory Cortex in Functional Dyspepsia.
Topics: Adult; Anxiety; Case-Control Studies; Depression; Dyspepsia; Female; Glutamic Acid; Glutamine; Humans; Middle Aged; Postprandial Period; Proton Magnetic Resonance Spectroscopy; Severity of Illness Index; Somatoform Disorders; Somatosensory Cortex; Tertiary Care Centers | 2017 |
Glutamatergic system and mTOR-signaling pathway participate in the antidepressant-like effect of inosine in the tail suspension test.
Topics: Analysis of Variance; Animals; Antidepressive Agents; Depression; Disease Models, Animal; Disks Large Homolog 4 Protein; Dose-Response Relationship, Drug; Excitatory Amino Acid Agents; Exploratory Behavior; Gene Expression Regulation; Glutamic Acid; Hindlimb Suspension; Inosine; Male; Mice; Receptors, AMPA; Signal Transduction; TOR Serine-Threonine Kinases | 2017 |
SIRT2 inhibition reverses anhedonia in the VGLUT1+/- depression model.
Topics: Anhedonia; Animals; Antidepressive Agents; Depression; Disease Models, Animal; Glutamic Acid; Histone Deacetylases; Imipramine; Male; Mice; Mice, Inbred C57BL; Prefrontal Cortex; RNA, Messenger; Serotonin; Sirtuin 2; Stress, Psychological; Vesicular Glutamate Transport Protein 1 | 2017 |
Periaqueductal Gray Glutamatergic Transmission Governs Chronic Stress-Induced Depression.
Topics: Anhedonia; Animals; Behavior, Animal; Depression; Disease Models, Animal; gamma-Aminobutyric Acid; Glutamic Acid; Male; Patch-Clamp Techniques; Periaqueductal Gray; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glucocorticoid; Stress, Psychological; Synaptic Transmission | 2018 |
Anterior cingulate cortex γ-aminobutyric acid deficits in youth with depression.
Topics: Adolescent; Anhedonia; Brain; Child; Depression; Depressive Disorder, Major; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Male; Proton Magnetic Resonance Spectroscopy; Severity of Illness Index; Young Adult | 2017 |
Cortical functional hyperconnectivity in a mouse model of depression and selective network effects of ketamine.
Topics: Animals; Antidepressive Agents; Aspartic Acid; Behavior, Animal; Cerebral Cortex; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Glutamic Acid; Ketamine; Male; Mice; Mice, Transgenic; Neural Pathways; Neurons; Social Behavior; Vesicular Glutamate Transport Proteins; Voltage-Sensitive Dye Imaging | 2017 |
Role of the Astroglial Glutamate Exchanger xCT in Ventral Hippocampus in Resilience to Stress.
Topics: Amino Acid Transport System y+; Animals; Astrocytes; Depression; Glutamic Acid; Hippocampus; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Random Allocation; Receptors, Metabotropic Glutamate; Stress, Psychological | 2017 |
Pregenual Anterior Cingulate Dysfunction Associated with Depression in OCD: An Integrated Multimodal fMRI/
Topics: Adult; Case-Control Studies; Depression; Female; Functional Neuroimaging; Glutamic Acid; Gyrus Cinguli; Humans; Magnetic Resonance Imaging; Male; Neural Pathways; Obsessive-Compulsive Disorder; Proton Magnetic Resonance Spectroscopy; Young Adult | 2018 |
Depression following traumatic brain injury in mice is associated with down-regulation of hippocampal astrocyte glutamate transporters by thrombin.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Astrocytes; Behavior, Animal; Blood-Brain Barrier; Brain Injuries, Traumatic; Depression; Down-Regulation; Enzyme Inhibitors; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Glutamic Acid; Hippocampus; Male; Mice; Receptor, PAR-1; rho-Associated Kinases; Thrombin; Vesicular Glutamate Transport Proteins | 2019 |
Effects of adolescent alcohol exposure on stress-induced reward deficits, brain CRF, monoamines and glutamate in adult rats.
Topics: Alcohol-Related Disorders; Anhedonia; Animals; Biogenic Monoamines; Brain; Central Nervous System Depressants; Corticotropin-Releasing Hormone; Depression; Dopamine; Ethanol; Glutamic Acid; Male; Nucleus Accumbens; Prefrontal Cortex; Rats; Rats, Wistar; Receptors, Corticotropin-Releasing Hormone; Reward; Self Stimulation; Serotonin; Stress, Psychological | 2018 |
Vesicular glutamate transporter 1 (VGLUT1)-mediated glutamate release and membrane GluA1 activation is involved in the rapid antidepressant-like effects of scopolamine in mice.
Topics: Animals; Antidepressive Agents; Cholinergic Antagonists; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Fasting; Feeding Behavior; Food Preferences; Glutamic Acid; Humans; Intercellular Signaling Peptides and Proteins; Locomotion; Male; Mice; Mice, Inbred C57BL; Prefrontal Cortex; Receptors, AMPA; Saccharin; Scopolamine; Social Behavior; Stress, Psychological; Swimming; Vesicular Glutamate Transport Protein 1; Water Deprivation | 2018 |
Hippocampal metabolic differences implicate distinctions between physical and psychological stress in four rat models of depression.
Topics: Animals; Behavior, Animal; Depression; Depressive Disorder, Major; Disease Models, Animal; Gas Chromatography-Mass Spectrometry; Glutamic Acid; Helplessness, Learned; Hippocampus; Lipid Metabolism; Male; Rats; Rats, Sprague-Dawley; Stress, Physiological; Stress, Psychological | 2018 |
Maternal Separation Induces Different Autophagic Responses in the Hippocampus and Prefrontal Cortex of Adult Rats.
Topics: Animals; Autophagy; Beclin-1; Depression; Disks Large Homolog 4 Protein; Exploratory Behavior; Glutamic Acid; Hippocampus; Male; Maternal Deprivation; Motor Activity; Prefrontal Cortex; Random Allocation; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 2018 |
Behavioral effects of toll-like receptor-4 antagonist 'eritoran' in an experimental model of depression: role of prefrontal and hippocampal neurogenesis and γ-aminobutyric acid/glutamate balance.
Topics: Animals; Antidepressive Agents; Brain-Derived Neurotrophic Factor; Depression; Depressive Disorder; Disaccharides; Disease Models, Animal; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Hypothalamo-Hypophyseal System; Male; Neurogenesis; Pituitary-Adrenal System; Prefrontal Cortex; Rats; Rats, Wistar; Stress, Psychological; Sugar Phosphates; Toll-Like Receptor 4 | 2018 |
Lung-injury depresses glutamatergic synaptic transmission in the nucleus tractus solitarii via discrete age-dependent mechanisms in neonatal rats.
Topics: Age Factors; Animals; Animals, Newborn; Bleomycin; Depression; Depressive Disorder; Excitatory Amino Acid Agents; Excitatory Postsynaptic Potentials; Female; Glutamic Acid; Lung Injury; Male; Medulla Oblongata; Neuronal Plasticity; Neurons; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Solitary Nucleus; Synapses; Synaptic Transmission | 2018 |
Prefrontal alterations in GABAergic and glutamatergic gene expression in relation to depression and suicide.
Topics: Adult; Depression; Female; Follow-Up Studies; gamma-Aminobutyric Acid; Gene Expression; Glutamic Acid; Humans; Male; Middle Aged; Prefrontal Cortex; Psychiatric Status Rating Scales; Receptors, GABA; Receptors, Glutamate; RNA, Messenger; Signal Transduction; Suicide; Synaptic Transmission; Young Adult | 2018 |
N-Acetyl and Glutamatergic Neurometabolites in Perisylvian Brain Regions of Methamphetamine Users.
Topics: Adolescent; Adult; Amphetamine-Related Disorders; Anxiety; Aspartic Acid; Central Nervous System Stimulants; Cerebral Cortex; Cross-Sectional Studies; Depression; Female; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Methamphetamine; Middle Aged; Young Adult | 2019 |
[Comparative study of the corticosterone and glutamate induced PC12 cells depression model by 1H NMR metabolomics].
Topics: Animals; Antioxidants; Corticosterone; Depression; Depressive Disorder; Fatty Acids; Glutamic Acid; Glycolysis; Metabolomics; PC12 Cells; Proton Magnetic Resonance Spectroscopy; Rats | 2017 |
Increased cocaine self-administration in rats lacking the serotonin transporter: a role for glutamatergic signaling in the habenula.
Topics: Animals; Behavior, Animal; Cocaine; Depression; Disks Large Homolog 4 Protein; Dopamine Uptake Inhibitors; Excitatory Amino Acid Transporter 2; Gene Expression Regulation; Gene Knockout Techniques; Glutamic Acid; Habenula; Rats; Rats, Transgenic; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Self Administration; Serotonin Plasma Membrane Transport Proteins | 2019 |
Attenuation of glutamatergic and nitrergic system contributes to the antidepressant-like effect induced by capsazepine in the forced swimming test.
Topics: 2-Amino-5-phosphonovalerate; Animals; Antidepressive Agents; Apomorphine; Arginine; Capsaicin; Cyclic GMP; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Routes; Enzyme Inhibitors; Exploratory Behavior; Glutamic Acid; Male; Microinjections; Nitric Oxide; Nitroprusside; Rats; Receptors, N-Methyl-D-Aspartate; Statistics, Nonparametric; Swimming | 2019 |
Mesopontine cholinergic inputs to midbrain dopamine neurons drive stress-induced depressive-like behaviors.
Topics: Acetylcholine; Animals; Behavior, Animal; Chronic Disease; Corticotropin-Releasing Hormone; Depression; Dopaminergic Neurons; Gene Silencing; Glutamic Acid; Male; Mesencephalon; Mice, Inbred C57BL; Models, Biological; Pons; Pontine Tegmentum; Receptors, Corticotropin-Releasing Hormone; Signal Transduction; Stress, Psychological; Ventral Tegmental Area | 2018 |
Neuro-metabolite profiles of rodent models of psychiatric dysfunctions characterised by MR spectroscopy.
Topics: Anhedonia; Animals; Choline; Depression; Disease Models, Animal; Excitatory Amino Acid Antagonists; Glutamic Acid; Glutamine; Hippocampus; Inositol; Magnetic Resonance Spectroscopy; Male; Memantine; Motor Activity; Rats; Rats, Wistar; Schizophrenia; Stress, Psychological; Sucrose; Taurine | 2019 |
Down-expressed GLT-1 in PSD astrocytes inhibits synaptic formation of NSC-derived neurons in vitro.
Topics: Animals; Astrocytes; Cell Differentiation; Depression; Disease Models, Animal; Excitatory Amino Acid Transporter 2; Gene Expression Regulation; Glutamic Acid; Hippocampus; Humans; Neural Stem Cells; Neurons; Rats; Stroke; Stroke Rehabilitation | 2019 |
Cannabinoid CB
Topics: Amygdala; Animals; Behavior, Animal; Cholecystokinin; Depression; Down-Regulation; Glutamic Acid; Male; Mice, Inbred C57BL; Neurons, Afferent; Nucleus Accumbens; Optogenetics; Receptor, Cannabinoid, CB1; Stress, Psychological; Synapses | 2019 |
[Altered Expression of Neurotransmitters Systems' Genes in the Ventral Tegmental Area of Depressive Male Mice: Data of RNA-Seq].
Topics: Animals; Anxiety; Depression; Disease Models, Animal; Dominance-Subordination; Dopamine; gamma-Aminobutyric Acid; Gene Expression Profiling; Gene Expression Regulation; Glutamic Acid; Humans; Male; Mice; Mice, Inbred C57BL; Nerve Tissue Proteins; Neurotransmitter Agents; Serotonin; Stress, Psychological; Synaptic Transmission; Ventral Tegmental Area | 2017 |
Chronic unpredictable mild stress induced depression-like behaviours and glutamate-glutamine cycling dysfunctions in both blood and brain of mice.
Topics: Animals; Behavior, Animal; Brain; Depression; Disease Models, Animal; Glutamic Acid; Glutamine; Male; Mice, Inbred Strains; Stress, Psychological | 2019 |
Lamotrigine Therapy and Biomarkers of Cerebral Energy Metabolism in Older Age Bipolar Depression.
Topics: Aged; Aging; Antipsychotic Agents; Aspartic Acid; Biomarkers; Bipolar Disorder; Cerebral Cortex; Creatine; Depression; Energy Metabolism; Female; Follow-Up Studies; Glutamic Acid; Glutamine; Humans; Lamotrigine; Male; Middle Aged; Proton Magnetic Resonance Spectroscopy; Severity of Illness Index; Treatment Outcome | 2019 |
The effect of pyruvate on the development and progression of post-stroke depression: A new therapeutic approach.
Topics: Animals; Depression; Glutamic Acid; Infarction, Middle Cerebral Artery; Male; Pyruvic Acid; Random Allocation; Rats; Rats, Sprague-Dawley; Stroke | 2019 |
Limbic neurochemical changes in patients with functional motor symptoms.
Topics: Adult; Affective Symptoms; Anxiety; Case-Control Studies; Creatine; Depression; Female; Glutamic Acid; Glutamine; Humans; Limbic System; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Movement Disorders; Quality of Life; Severity of Illness Index | 2019 |
Memantine ameliorates learning and memory disturbance and the behavioral and psychological symptoms of dementia in thiamine-deficient mice.
Topics: Administration, Oral; Animals; Anxiety; Behavior, Animal; Biogenic Monoamines; Body Weight; Dementia; Depression; Disease Models, Animal; Glutamic Acid; Hippocampus; Locomotion; Male; Maze Learning; Memantine; Memory; Mice; Thiamine Deficiency | 2019 |
Role of Serotonin and Noradrenaline in the Rapid Antidepressant Action of Ketamine.
Topics: Animals; Antidepressive Agents; Depression; Dorsal Raphe Nucleus; Glutamic Acid; Ketamine; Male; Motor Activity; Norepinephrine; Prefrontal Cortex; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Serotonergic Neurons; Serotonin | 2019 |
Increased Homer1-mGluR5 mediates chronic stress-induced depressive-like behaviors and glutamatergic dysregulation via activation of PERK-eIF2α.
Topics: Animals; Behavior, Animal; Corticosterone; Depression; Eukaryotic Initiation Factor-2; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Hippocampus; Homer Scaffolding Proteins; Male; Methoxyhydroxyphenylglycol; Mice; Phosphorylation; Pyramidal Cells; Receptor, Metabotropic Glutamate 5; Social Behavior; Stress, Psychological; Synaptic Transmission | 2019 |
Development of an underivatized LC-MS/MS method for quantitation of 14 neurotransmitters in rat hippocampus, plasma and urine: Application to CUMS induced depression rats.
Topics: Animals; Blood Chemical Analysis; Chromatography, Liquid; Depression; Disease Models, Animal; Glutamic Acid; Hippocampus; Kynurenic Acid; Kynurenine; Limit of Detection; Linear Models; Male; Neurotransmitter Agents; Phenylalanine; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Tandem Mass Spectrometry; Tryptophan; Urinalysis | 2019 |
[Modulation of hippocampal glutamate and NMDA/AMPA receptor by homocysteine in chronic unpredictable mild stress-induced rat depression].
Topics: Animals; Behavior, Animal; Depression; Dizocilpine Maleate; Glutamic Acid; Hippocampus; Homocysteine; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Stress, Psychological | 2013 |
Biochemical correlates of neuropsychiatric illness in maple syrup urine disease.
Topics: Adolescent; Adult; Affect; Anxiety; Aspartic Acid; Attention; Brain; Case-Control Studies; Child; Child, Preschool; Creatine; Depression; Female; Glutamic Acid; Humans; Impulsive Behavior; Liver Transplantation; Male; Maple Syrup Urine Disease; Prevalence; Psychomotor Agitation; Risk; Young Adult | 2013 |
Does increasing the ratio of AMPA-to-NMDA receptor mediated neurotransmission engender antidepressant action? Studies in the mouse forced swim and tail suspension tests.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Brain; Depression; Excitatory Amino Acid Agonists; Female; Glutamic Acid; Hindlimb Suspension; Mice; Neurotransmitter Agents; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Swimming; Synaptic Transmission; Treatment Outcome; Up-Regulation | 2013 |
Effect of interferon-α on cortical glutamate in patients with hepatitis C: a proton magnetic resonance spectroscopy study.
Topics: Adult; Cerebral Cortex; Depression; Female; Glutamic Acid; Glutamine; Hepatitis C; Humans; Inflammation; Interferon-alpha; Magnetic Resonance Spectroscopy; Male; Middle Aged; Protons | 2014 |
Involvement of pGluR1, EAAT2 and EAAT3 in offspring depression induced by prenatal stress.
Topics: Animals; Blotting, Western; Depression; Excitatory Amino Acid Transporter 2; Excitatory Amino Acid Transporter 3; Female; Glutamic Acid; Hindlimb Suspension; Hippocampus; Neostriatum; Prefrontal Cortex; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Receptors, AMPA; Restraint, Physical; RNA | 2013 |
Increased ratio of glutamate/glutamine to creatine in the right hippocampus contributes to depressive symptoms in patients with epilepsy.
Topics: Adolescent; Adult; Creatine; Depression; Epilepsy; Female; Functional Laterality; Glutamic Acid; Glutamine; Hippocampus; Humans; Male; Middle Aged; Neuropsychological Tests; Prospective Studies; Psychiatric Status Rating Scales; Young Adult | 2013 |
A follow-up study of neurometabolic alterations in female concussed athletes.
Topics: Aspartic Acid; Athletes; Athletic Injuries; Brain Chemistry; Brain Concussion; Creatine; Depression; Female; Follow-Up Studies; Glutamic Acid; Glutamine; Hippocampus; Humans; Image Processing, Computer-Assisted; Inositol; Magnetic Resonance Imaging; Male; Neuropsychological Tests; Prefrontal Cortex; Young Adult | 2014 |
Dysfunctional glutamatergic and γ-aminobutyric acidergic activities in prefrontal cortex of mice in social defeat model of depression.
Topics: Animals; Carbon-13 Magnetic Resonance Spectroscopy; Depression; Depressive Disorder; Disease Models, Animal; GABAergic Neurons; gamma-Aminobutyric Acid; Glutamic Acid; Male; Mice; Mice, Inbred C57BL; Neurons; Prefrontal Cortex; Social Behavior; Stress, Psychological | 2014 |
An organoselenium compound improves behavioral, endocrinal and neurochemical changes induced by corticosterone in mice.
Topics: Adrenocorticotropic Hormone; Animals; Anxiety; Behavior, Animal; Corticosterone; Depression; Disease Models, Animal; Glutamic Acid; Hippocampus; Mice; Organoselenium Compounds; Prefrontal Cortex; Serotonin | 2014 |
[Hippocampus quinolinic acid modulates glutamate and NMDAR/mGluR1 in chronic unpredictable mild stress-induced depression].
Topics: Animals; Behavior, Animal; Depression; Dizocilpine Maleate; Glutamic Acid; Hippocampus; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Stress, Psychological | 2013 |
IFN-alpha-induced cortical and subcortical glutamate changes assessed by magnetic resonance spectroscopy.
Topics: Adult; Aged; Antiviral Agents; Brain; Creatine; Cytokines; Depression; Female; Glutamic Acid; Hepacivirus; Hepatitis C; Humans; Interferon-alpha; Longitudinal Studies; Magnetic Resonance Spectroscopy; Male; Middle Aged; Statistics as Topic | 2014 |
The effects of antidepressant treatment in prenatally stressed rats support the glutamatergic hypothesis of stress-related disorders.
Topics: Animals; Antidepressive Agents; Anxiety; Depression; Female; Glutamic Acid; Male; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Stress, Psychological; Treatment Outcome | 2014 |
Current drug development for antidepressants and ideas addressing downstream glutamate: the ketamine example.
Topics: Animals; Antidepressive Agents; Depression; Drug Discovery; Glutamic Acid; Humans; Ketamine | 2014 |
Downregulation of neuregulin 1-ErbB4 signaling in parvalbumin interneurons in the rat brain may contribute to the antidepressant properties of ketamine.
Topics: Animals; Antidepressive Agents; Brain; Depression; Down-Regulation; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamic Acid; Interneurons; Ketamine; Locomotion; Male; Neuregulin-1; Parvalbumins; Rats; Rats, Wistar; Receptor, ErbB-4; Signal Transduction | 2014 |
[1H NMR based metabonomics study on the antidepressant effect of genipin in rat hippocampus].
Topics: Alanine; Animals; Antidepressive Agents; Aspartic Acid; Behavior, Animal; Chronic Disease; Depression; Gardenia; Glutamic Acid; Glycine; Hippocampus; Inositol; Iridoids; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Metabolomics; Plants, Medicinal; Rats; Rats, Sprague-Dawley | 2014 |
Role of glutamate and advantages of combining memantine with a 5HT6 ligand in a model of depression.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Depression; Disease Models, Animal; Glutamic Acid; Ligands; Male; Memantine; Motor Activity; N-Methylaspartate; Piperazines; Prefrontal Cortex; Rats; Rats, Wistar; Serotonin; Serotonin Antagonists; Sulfonamides; Swimming | 2014 |
Effects of D-series resolvins on behavioral and neurochemical changes in a fibromyalgia-like model in mice.
Topics: Analgesics; Animals; Antidepressive Agents; Brain; Depression; Disease Models, Animal; Docosahexaenoic Acids; Dopamine; Fibromyalgia; gamma-Aminobutyric Acid; Glutamic Acid; Hot Temperature; Hyperalgesia; Male; Mice; Nociceptive Pain; Pregabalin; Serotonin; Spinal Cord; Touch | 2014 |
Plasma levels of glutamate during stroke is associated with development of post-stroke depression.
Topics: Aged; Aged, 80 and over; Depression; Female; Follow-Up Studies; Glutamic Acid; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Patient Admission; Prognosis; Severity of Illness Index; Stroke | 2014 |
Dentate gyrus-CA3 glutamate release/NMDA transmission mediates behavioral despair and antidepressant-like responses to leptin.
Topics: Animals; Antidepressive Agents; CA3 Region, Hippocampal; Dentate Gyrus; Depression; Disease Models, Animal; Enzyme Inhibitors; Excitatory Amino Acid Agents; Gene Expression Regulation; Glutamic Acid; Leptin; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Motor Activity; N-Methylaspartate; Receptors, Leptin; RNA, Untranslated; Synapses; Synaptic Transmission; Wakefulness | 2015 |
Defects in dendrite and spine maturation and synaptogenesis associated with an anxious-depressive-like phenotype of GABAA receptor-deficient mice.
Topics: Animals; Anxiety; Brain-Derived Neurotrophic Factor; Cells, Cultured; Cerebral Cortex; Dendrites; Depression; Depressive Disorder, Major; Disease Models, Animal; Female; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Mice, 129 Strain; Neurogenesis; Phenotype; Receptors, GABA-A; Synapses | 2015 |
Propofol inhibits inflammatory cytokine-mediated glutamate uptake dysfunction to alleviate learning/memory impairment in depressed rats undergoing electroconvulsive shock.
Topics: Analysis of Variance; Animals; Cytokines; Depression; Disease Models, Animal; Food Deprivation; Food Preferences; Gene Expression Regulation; Glutamic Acid; Hypnotics and Sedatives; Learning Disabilities; Male; Maze Learning; Propofol; Rats; Rats, Sprague-Dawley; Water Deprivation | 2015 |
[The interaction between gamma-aminobutyric acid and other related neurotransmitters in depression].
Topics: Animals; Brain; Depression; Dopamine; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Neurotransmitter Agents; Serotonin | 2014 |
Mood regulation. GABA/glutamate co-release controls habenula output and is modified by antidepressant treatment.
Topics: Animals; Antidepressive Agents; Channelrhodopsins; Depression; Entopeduncular Nucleus; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamic Acid; Habenula; Male; Mice; Mice, Inbred C57BL; Neurons; Rats; Rats, Sprague-Dawley; Synaptic Transmission; Vesicular Glutamate Transport Protein 2 | 2014 |
Shu‑Yu capsule, a Traditional Chinese Medicine formulation, attenuates premenstrual syndrome depression induced by chronic stress constraint.
Topics: Animals; Body Mass Index; Depression; Drugs, Chinese Herbal; Female; Fluoxetine; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Medicine, Chinese Traditional; Oleanolic Acid; Premenstrual Syndrome; Rats; Rats, Wistar; Saponins | 2014 |
GluN2B-containing NMDA receptors regulate depression-like behavior and are critical for the rapid antidepressant actions of ketamine.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Cerebral Cortex; Depression; Excitatory Postsynaptic Potentials; Gene Knockout Techniques; Glutamic Acid; Ketamine; Mice, Knockout; Neurons; Prefrontal Cortex; Protein Biosynthesis; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission | 2014 |
Cognitive impairment induced by permanent bilateral common carotid occlusion exacerbates depression-related behavioral, biochemical, immunological and neuronal markers.
Topics: Analysis of Variance; Animals; Carotid Artery Diseases; Chromatography, High Pressure Liquid; Cognition Disorders; Cues; Depression; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Glutamic Acid; Glycine; Hindlimb Suspension; Hippocampus; Interleukin-6; Male; Maze Learning; Neurons; Rats; Rats, Sprague-Dawley; Stress, Psychological; Swimming; Time Factors | 2015 |
Genetic disruption of 2-arachidonoylglycerol synthesis reveals a key role for endocannabinoid signaling in anxiety modulation.
Topics: Amygdala; Animals; Anxiety; Arachidonic Acids; Depression; Disease Models, Animal; Endocannabinoids; Female; Glutamic Acid; Glycerides; Male; Mice, Knockout; Synaptic Transmission | 2014 |
Rave drug tested against depression.
Topics: Antidepressive Agents; Brain; Clinical Trials as Topic; Depression; Glutamic Acid; Humans; Ketamine; Neuroimaging; Off-Label Use; Patents as Topic; Suicide; Suicide Prevention; Time Factors | 2015 |
Hippocampal-Dependent Antidepressant Action of the H3 Receptor Antagonist Clobenpropit in a Rat Model of Depression.
Topics: Animals; Antidepressive Agents; Anxiety; Behavior, Animal; Depression; Disease Models, Animal; Excitatory Postsynaptic Potentials; Glutamic Acid; Hippocampus; Histamine H3 Antagonists; Imidazoles; Long-Term Potentiation; Male; Memory Disorders; Patch-Clamp Techniques; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Thiourea | 2015 |
Anxious phenotypes plus environmental stressors are related to brain DNA damage and changes in NMDA receptor subunits and glutamate uptake.
Topics: Animals; Anxiety; Brain; Depression; DNA Damage; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Glutamic Acid; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Species Specificity; Stress, Psychological | 2015 |
Spectroscopic markers of memory impairment, symptom severity and age of onset in older people with lifetime depression: Discrete roles of N-acetyl aspartate and glutamate.
Topics: Aged; Aspartic Acid; Case-Control Studies; Cross-Sectional Studies; Depression; Female; Glutamic Acid; Humans; Magnetic Resonance Spectroscopy; Male; Memory Disorders; Middle Aged; Neuropsychological Tests; Prefrontal Cortex | 2015 |
m-Trifluoromethyl-diphenyl diselenide, a multi-target selenium compound, prevented mechanical allodynia and depressive-like behavior in a mouse comorbid pain and depression model.
Topics: Adrenocorticotropic Hormone; Animals; Antidepressive Agents; Brain; Corticosterone; Cytokines; Depression; Disease Models, Animal; Functional Laterality; Glutamic Acid; Hyperalgesia; Male; Mice; Motor Activity; Neuralgia; Organosilicon Compounds; Peripheral Nerve Injuries; Serotonin; Swimming; Synaptosomes; Tritium | 2015 |
The positive effect on ketamine as a priming adjuvant in antidepressant treatment.
Topics: Animals; Antidepressive Agents; Anxiety; Aspartic Acid; Behavior, Animal; Brain; Depression; Depressive Disorder, Major; Disease Models, Animal; Drug Therapy, Combination; Fluoxetine; Glutamic Acid; Imipramine; Ketamine; Male; Prefrontal Cortex; Pyramidal Cells; Rats; Rats, Wistar; Stress, Psychological | 2015 |
Propofol can Protect Against the Impairment of Learning-memory Induced by Electroconvulsive Shock via Tau Protein Hyperphosphorylation in Depressed Rats.
Topics: Animals; Depression; Dizocilpine Maleate; Electroshock; Glutamic Acid; Learning Disabilities; Male; Memory Disorders; Phosphorylation; Propofol; Rats; Rats, Sprague-Dawley; tau Proteins | 2015 |
Alteration by p11 of mGluR5 localization regulates depression-like behaviors.
Topics: Animals; Annexin A2; Depression; GABAergic Neurons; Glutamic Acid; HEK293 Cells; Humans; Mice; Mice, Inbred C57BL; Neural Inhibition; Neurons; Parvalbumins; Receptor, Metabotropic Glutamate 5; S100 Proteins; Signal Transduction; Synapses | 2015 |
Reward related neurotransmitter changes in a model of depression: An in vivo microdialysis study.
Topics: Animals; Depression; Disease Models, Animal; Dopamine; Dopamine Agents; gamma-Aminobutyric Acid; Glutamic Acid; Male; Methamphetamine; Microdialysis; Neurotransmitter Agents; Nucleus Accumbens; Rats; Rats, Wistar; Reward; Self Administration; Serotonin | 2015 |
Increased serum levels of serine enantiomers in patients with depression.
Topics: Adult; Biomarkers; Case-Control Studies; Depression; Female; Glutamic Acid; Glutamine; Glycine; Humans; Male; Middle Aged; Serine; Stereoisomerism; Young Adult | 2016 |
Stress dynamically regulates behavior and glutamatergic gene expression in hippocampus by opening a window of epigenetic plasticity.
Topics: Animals; Anxiety; Behavior, Animal; Brain-Derived Neurotrophic Factor; Dentate Gyrus; Depression; Epigenesis, Genetic; Glutamic Acid; Histones; Male; Mice; Mice, Mutant Strains; p300-CBP Transcription Factors; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Stress, Psychological; Synaptic Transmission | 2015 |
Chronic pain causes a persistent anxiety state leading to increased ethanol intake in CD1 mice.
Topics: Alcohol Drinking; Animals; Anxiety; Behavior, Animal; Brain-Derived Neurotrophic Factor; Chronic Pain; Depression; Disease Models, Animal; Ethanol; Glutamic Acid; Hyperalgesia; Interleukin-6; Male; Mice; Prefrontal Cortex; Serotonin; Time Factors | 2016 |
Ovarian steroids regulate gene expression in the dorsal raphe of old female macaques.
Topics: Animals; Cell Survival; Depression; DNA Repair; Dorsal Raphe Nucleus; Estradiol; Estrogen Replacement Therapy; Female; Gene Expression; Gene Expression Regulation, Developmental; Glutamic Acid; Macaca mulatta; Molecular Chaperones; Neurodegenerative Diseases; Ovariectomy; Progesterone; Reverse Transcriptase Polymerase Chain Reaction; Serotonin; Synapses; Synaptic Transmission; Time Factors | 2016 |
Conceptual convergence: increased inflammation is associated with increased basal ganglia glutamate in patients with major depression.
Topics: Adult; Basal Ganglia; Brain; C-Reactive Protein; Cross-Sectional Studies; Depression; Depressive Disorder, Major; Female; Glutamic Acid; Gyrus Cinguli; Humans; Inflammation; Interferon-alpha; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged | 2016 |
When the party is over: depressive-like states in rats following termination of cortical D1 receptor overexpression.
Topics: Animals; Behavior, Animal; Depression; Glutamic Acid; Male; Motor Activity; Neurons; Nucleus Accumbens; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Reward | 2016 |
A sensitive and practical RP-HPLC-FLD for determination of the low neuroactive amino acid levels in body fluids and its application in depression.
Topics: Aged; Aged, 80 and over; Amino Acids; Bipolar Disorder; Body Fluids; Case-Control Studies; Chromatography, High Pressure Liquid; Depression; Depressive Disorder; Female; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Hydrogen-Ion Concentration; Male; Middle Aged; Mood Disorders | 2016 |
Disruption of the HPA-axis through corticosterone-release pellets induces robust depressive-like behavior and reduced BDNF levels in mice.
Topics: Animals; Behavior, Animal; Brain-Derived Neurotrophic Factor; Corticosterone; Depression; Dopamine; Glutamic Acid; Hippocampus; Hypothalamus; Male; Mice; Mice, Inbred C57BL; Norepinephrine; Nucleus Accumbens; Phenotype; Pituitary-Adrenal System; Receptors, Glucocorticoid; Serotonin | 2016 |
Hypothalamic Proteomic Analysis Reveals Dysregulation of Glutamate Balance and Energy Metabolism in a Mouse Model of Chronic Mild Stress-Induced Depression.
Topics: Animals; Corticosterone; Depression; Depressive Disorder; Disease Models, Animal; Energy Metabolism; Glutamic Acid; Hypothalamo-Hypophyseal System; Hypothalamus; Male; Mice, Inbred C57BL; Pituitary-Adrenal System; Proteomics; Stress, Physiological | 2016 |
Repeated ketamine treatment induces sex-specific behavioral and neurochemical effects in mice.
Topics: Animals; Antidepressive Agents; Anxiety; Aspartic Acid; Depression; Female; Glutamic Acid; Hippocampus; Hydroxyindoleacetic Acid; Ketamine; Male; Mice; Mice, Inbred C57BL; Serotonin; Sex Characteristics; SNARE Proteins; Synapsins; Syntaxin 1 | 2016 |
Brain glutamic acid decarboxylase-67kDa alterations induced by magnesium treatment in olfactory bulbectomy and chronic mild stress models in rats.
Topics: Animals; Antidepressive Agents; Brain; Chronic Disease; Depression; Disease Models, Animal; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamic Acid; Magnesium; Male; Olfactory Bulb; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Stress, Psychological | 2016 |
Evidence in support of using a neurochemistry approach to identify therapy for both epilepsy and associated depression.
Topics: Animals; Anticonvulsants; Brain; Depression; Depressive Disorder; Disease Models, Animal; Dopamine; Epilepsy; Glutamic Acid; Hindlimb Suspension; Kindling, Neurologic; Male; Mice; Neurochemistry; Norepinephrine; Pentylenetetrazole; Seizures; Serotonin; Treatment Outcome; Valproic Acid | 2016 |
Prefrontal changes in the glutamate-glutamine cycle and neuronal/glial glutamate transporters in depression with and without suicide.
Topics: Aged; Aged, 80 and over; Amino Acid Transport System X-AG; Depression; Female; Glutamic Acid; Glutamine; Humans; Male; Middle Aged; Netherlands; Postmortem Changes; Prefrontal Cortex; Psychiatric Status Rating Scales; Suicide | 2016 |
Targeted Metabolomic Pathway Analysis and Validation Revealed Glutamatergic Disorder in the Prefrontal Cortex among the Chronic Social Defeat Stress Mice Model of Depression.
Topics: Animals; Blotting, Western; Depression; Disease Models, Animal; Glutamic Acid; Metabolic Networks and Pathways; Metabolomics; Mice; Prefrontal Cortex; Real-Time Polymerase Chain Reaction; Stress, Psychological | 2016 |
Neuropsin Inactivation Has Protective Effects against Depressive-Like Behaviours and Memory Impairment Induced by Chronic Stress.
Topics: Animals; Corticosterone; Depression; Disease Models, Animal; Glutamic Acid; Hippocampus; Humans; Kallikreins; Memory Disorders; Mice; Mice, Knockout; Stress, Psychological | 2016 |
Soluble N-ethylmaleimide-sensitive Factor Attachment Receptor (SNARE) Protein Involved in the Remission of Depression by Acupuncture in Rats.
Topics: Acupuncture Therapy; Animals; Depression; Glutamic Acid; Hippocampus; Humans; Male; Rats; Rats, Sprague-Dawley; SNARE Proteins | 2016 |
A Neuroprotective Effect of the Glutamate Receptor Antagonist MK801 on Long-Term Cognitive and Behavioral Outcomes Secondary to Experimental Cerebral Malaria.
Topics: Animals; Anxiety; Behavior, Animal; Cognition; Cytokines; Depression; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Hippocampus; Leukocytes; Magnetic Resonance Imaging; Malaria, Cerebral; Memory, Short-Term; Mice, Inbred C57BL; Nerve Growth Factors; Neuroprotective Agents; Organ Size; Parasitemia; Phenotype; Plasmodium berghei; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Survival Analysis; Up-Regulation | 2017 |
Hypothalamic damage in multiple sclerosis correlates with disease activity, disability, depression, and fatigue.
Topics: Adult; Aging; Aspartic Acid; Case-Control Studies; Choline; Creatine; Cross-Sectional Studies; Depression; Disability Evaluation; Fatigue; Female; Glutamic Acid; Humans; Hypothalamus; Inositol; Male; Multiple Sclerosis, Chronic Progressive; Multiple Sclerosis, Relapsing-Remitting; Proton Magnetic Resonance Spectroscopy; Psychiatric Status Rating Scales; Severity of Illness Index | 2017 |
Protective effect of spermine against pentylenetetrazole kindling epilepsy induced comorbidities in mice.
Topics: Animals; Arginine; Avoidance Learning; Brain; Catecholamines; Comorbidity; Depression; Epilepsy; gamma-Aminobutyric Acid; Glutamic Acid; Kindling, Neurologic; Male; Mice; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Pentylenetetrazole; Spermine | 2017 |
Increases in intracellular calcium triggered by channelrhodopsin-2 potentiate the response of metabotropic glutamate receptor mGluR7.
Topics: Algal Proteins; Aminobutyrates; Animals; Calcium; Calcium Signaling; Calmodulin; Chelating Agents; Chlamydomonas reinhardtii; Depression; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Female; Gene Expression; Glutamic Acid; Humans; Light; Long-Term Potentiation; Oocytes; Receptors, Metabotropic Glutamate; Recombinant Proteins; Rhodopsin; Synapses; Xenopus | 2008 |
Glial pathology in an animal model of depression: reversal of stress-induced cellular, metabolic and behavioral deficits by the glutamate-modulating drug riluzole.
Topics: Acetates; Animals; Avoidance Learning; Behavioral Symptoms; Depression; Disease Models, Animal; Food Preferences; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Glutamic Acid; Isotopes; Magnetic Resonance Spectroscopy; Male; Neuroglia; Neuroprotective Agents; Prefrontal Cortex; Radionuclide Imaging; Rats; Rats, Sprague-Dawley; Riluzole; RNA, Messenger; Statistics, Nonparametric; Stress, Psychological; Sucrose; Sweetening Agents | 2010 |
The change in plasma GABA, glutamine and glutamate levels in fluoxetine- or S-citalopram-treated female patients with major depression.
Topics: Antidepressive Agents, Second-Generation; Case-Control Studies; Chromatography, High Pressure Liquid; Citalopram; Depression; Female; Fluoxetine; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans | 2009 |
Targeting glial physiology and glutamate cycling in the treatment of depression.
Topics: Animals; Depression; Disease Models, Animal; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Magnetic Resonance Spectroscopy; Neuroglia; Riluzole; Stress, Psychological | 2009 |
Increased vulnerability to depressive-like behavior of mice with decreased expression of VGLUT1.
Topics: Analysis of Variance; Animals; Brain; Brain Chemistry; Carbon Isotopes; Depression; Disease Models, Animal; Down-Regulation; Electron Transport Complex IV; Excitatory Amino Acid Transporter 1; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamic Acid; Magnetic Resonance Spectroscopy; Male; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Neuropsychological Tests; Recognition, Psychology; Stress, Psychological; Swimming; Vesicular Glutamate Transport Protein 1 | 2009 |
Altered prefrontal glutamate-glutamine-gamma-aminobutyric acid levels and relation to low cognitive performance and depressive symptoms in type 1 diabetes mellitus.
Topics: Adult; Cognition Disorders; Depression; Diabetes Mellitus, Type 1; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Glycated Hemoglobin; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Neuropsychological Tests; Prefrontal Cortex | 2009 |
Antidepressants induce regionally discrete, sex-dependent changes in brain's glutamate content.
Topics: Animals; Antidepressive Agents; Brain; Depression; Female; Glutamic Acid; Male; Rats; Sex Factors; Tissue Distribution | 2009 |
Increased glutamate/glutamine compounds in the brains of patients with fibromyalgia: a magnetic resonance spectroscopy study.
Topics: Anxiety; Brain; Brain Mapping; Chi-Square Distribution; Creatine; Depression; Female; Fibromyalgia; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; Psychiatric Status Rating Scales | 2010 |
Effects of depressive-like behavior of rats on brain glutamate uptake.
Topics: Animals; Brain; Cerebral Cortex; Corpus Striatum; Depression; Female; Glutamic Acid; Helplessness, Learned; Hippocampus; Rats; Rats, Wistar; Stress, Psychological | 2010 |
Potential role of glutamate neurotransmission in the pathogenesis of ischemic brain damage and of depression. Effects of L-kynurenine on the survival of the hippocampal neurons and on the corticocerebral blood flow in ischemic animal models.
Topics: Animals; Brain Ischemia; Cell Survival; Cerebrovascular Circulation; Chromatography, High Pressure Liquid; Citalopram; Depression; Disease Models, Animal; Electrophysiology; Fluoxetine; Glutamic Acid; Hippocampus; Kynurenine; Male; Rabbits; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Synaptic Transmission; Wakefulness | 2010 |
Effects of electroconvulsive therapy and propofol on spatial memory and glutamatergic system in hippocampus of depressed rats.
Topics: Animals; Combined Modality Therapy; Depression; Disease Models, Animal; Electroconvulsive Therapy; Glutamic Acid; Hippocampus; Hypnotics and Sedatives; Male; Memory; Propofol; Rats; Rats, Sprague-Dawley; Reference Standards | 2010 |
Protective effect of gan mai da zao decoction in unpredictable chronic mild stress-induced behavioral and biochemical alterations.
Topics: Animals; Behavior, Animal; Blotting, Western; Chromatography, High Pressure Liquid; Chronic Disease; Depression; Disease Models, Animal; Drugs, Chinese Herbal; Frontal Lobe; Glutamic Acid; Hippocampus; Male; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Stress, Psychological; Sucrose | 2010 |
Elevated cortical glutamate in young people at increased familial risk of depression.
Topics: Adolescent; Cerebral Cortex; Depression; Depressive Disorder; Depressive Disorder, Major; Family; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; Male; Occipital Lobe; Risk Factors; Young Adult | 2011 |
Chronic stress and impaired glutamate function elicit a depressive-like phenotype and common changes in gene expression in the mouse frontal cortex.
Topics: Animals; Behavior, Animal; Depression; Depressive Disorder; Disease Models, Animal; Frontal Lobe; Gene Expression Profiling; Gene Expression Regulation; Glutamic Acid; Humans; Male; Mice; Mice, Inbred C57BL; Microarray Analysis; Mood Disorders; Neurotransmitter Agents; Phenotype; Pleasure; RNA; Stress, Psychological; Sucrose; Time Factors; Vesicular Glutamate Transport Protein 1 | 2011 |
Cracking the moody brain: lifting the mood with ketamine.
Topics: Antidepressive Agents; Depression; Glutamic Acid; Humans; Ketamine; Models, Neurological; Protein Binding; Receptors, N-Methyl-D-Aspartate; Signal Transduction; TOR Serine-Threonine Kinases | 2010 |
[The association of hippocampal glutamate with depression and the effects on gastric mobility].
Topics: Animals; Depression; Gastrointestinal Diseases; Gastrointestinal Motility; Glutamic Acid; Hippocampus; Male; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 2009 |
Glutamate level detection by magnetic resonance spectroscopy in patients with post-stroke depression.
Topics: Aged; Aspartic Acid; Brain; Brain Mapping; Creatine; Depression; Female; Glutamic Acid; Humans; Inositol; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Protons; Psychiatric Status Rating Scales; Stroke | 2012 |
Resting glutamate levels and rapid glutamate transients in the prefrontal cortex of the Flinders Sensitive Line rat: a genetic rodent model of depression.
Topics: Age Factors; Animals; Depression; Disease Models, Animal; Glutamic Acid; Male; Microdialysis; Prefrontal Cortex; Rats; Rats, Mutant Strains; Rest; Time Factors | 2011 |
Stressor-induced NMDAR dysfunction as a unifying hypothesis for the aetiology, pathogenesis and comorbidity of clinical depression.
Topics: Animals; Depression; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Models, Theoretical; Oxidation-Reduction; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Transcription, Genetic | 2011 |
Increase of hippocampal glutamate after electroconvulsive treatment: a quantitative proton MR spectroscopy study at 9.4 T in an animal model of depression.
Topics: Animals; Choline; Depression; Disease Models, Animal; Electroconvulsive Therapy; gamma-Aminobutyric Acid; Glucose; Glutamic Acid; Glutamine; Helplessness, Learned; Hippocampus; Magnetic Resonance Spectroscopy; Male; Rats; Rats, Sprague-Dawley; Taurine | 2012 |
Antidepressant-like and neuroprotective effects of Aloysia gratissima: investigation of involvement of L-arginine-nitric oxide-cyclic guanosine monophosphate pathway.
Topics: Administration, Oral; Animals; Antidepressive Agents; Arginine; Behavior, Animal; Blotting, Western; Cell Survival; Cyclic GMP; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Glutamic Acid; Hippocampus; Male; Medicine, Traditional; Mice; Motor Activity; Neuroprotective Agents; Neurotransmitter Agents; Nitric Oxide; Nitric Oxide Synthase Type II; Phosphorylation; Plant Components, Aerial; Plant Extracts; Plants, Medicinal; Proto-Oncogene Proteins c-akt; Signal Transduction; Solvents; Time Factors; Verbenaceae; Water | 2011 |
Polymorphisms within the metabotropic glutamate receptor 1 gene are associated with depression phenotypes.
Topics: Adolescent; Adult; Aged; Case-Control Studies; Corticotropin-Releasing Hormone; Depression; Depressive Disorder; Dexamethasone; Female; Genetic Predisposition to Disease; Genotype; Glutamic Acid; Hippocampus; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Phenotype; Pituitary-Adrenal Function Tests; Polymorphism, Single Nucleotide; Receptors, Metabotropic Glutamate | 2012 |
Long lasting effects of early-life stress on glutamatergic/GABAergic circuitry in the rat hippocampus.
Topics: Age Factors; Animals; Antidepressive Agents, Second-Generation; Corticosterone; Cyclohexanols; Depression; Excitatory Amino Acid Transporter 1; Female; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamic Acid; Hippocampus; Male; Maternal Deprivation; Nerve Net; Neurons; Rats; Venlafaxine Hydrochloride | 2012 |
[Orbitofrontal cortex action of 5-hydroxytryptamine, glutamate and nitric oxide in an acute forced swimming stress-induced depression model].
Topics: Animals; Depression; Frontal Lobe; Glutamic Acid; Male; Nitric Oxide; Rats; Rats, Sprague-Dawley; Serotonin; Stress, Physiological; Swimming | 2011 |
Dysfunctional astrocytic regulation of glutamate transmission in a rat model of depression.
Topics: Animals; Astrocytes; Depression; Disease Models, Animal; Excitatory Amino Acid Agents; Excitatory Postsynaptic Potentials; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Hippocampus; Humans; In Vitro Techniques; Male; Nerve Tissue Proteins; Patch-Clamp Techniques; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Recognition, Psychology; Serine; Sodium Channel Blockers; Statistics, Nonparametric; Swimming; Synaptic Transmission; Tetrodotoxin | 2013 |
Glutamate-based depression GBD.
Topics: Affect; Alzheimer Disease; Arthritis, Rheumatoid; Chronic Pain; Cognition; Coronary Artery Disease; Depression; Diabetes Complications; Fibromyalgia; Glutamic Acid; Gyrus Cinguli; Humans; Huntington Disease; Inflammation; Interferons; Models, Neurological; Models, Psychological; Parkinson Disease; Receptors, N-Methyl-D-Aspartate; Risk Factors; Stroke; Synaptic Transmission | 2012 |
Chronic restraint stress causes anxiety- and depression-like behaviors, downregulates glucocorticoid receptor expression, and attenuates glutamate release induced by brain-derived neurotrophic factor in the prefrontal cortex.
Topics: Animals; Anxiety; Behavior, Animal; Brain-Derived Neurotrophic Factor; Depression; Disease Models, Animal; Down-Regulation; Glucocorticoids; Glutamic Acid; Male; Nerve Tissue Proteins; Prefrontal Cortex; Rats; Rats, Wistar; Receptor, trkB; Receptors, Glucocorticoid; Receptors, Growth Factor; Receptors, Nerve Growth Factor; Restraint, Physical; Stress, Psychological | 2012 |
Social vs. environmental stress models of depression from a behavioural and neurochemical approach.
Topics: Animals; Anxiety; Behavior, Animal; Brain Stem; Depression; Disease Models, Animal; Dopamine; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Male; Mice; Neurotransmitter Agents; Prefrontal Cortex; Serotonin; Social Dominance; Stress Disorders, Post-Traumatic; Stress, Psychological | 2013 |
Effects of propofol and dizocilpine maleate on the cognitive abilities and the hyperphosphorylation of Tau protein of rats after the electroconvulsive therapy.
Topics: Animals; Depression; Disease Models, Animal; Dizocilpine Maleate; Electroconvulsive Therapy; Glutamic Acid; Hippocampus; Male; Maze Learning; Memory; Phosphorylation; Propofol; Rats; Rats, Sprague-Dawley; tau Proteins | 2012 |
Bidirectional regulation of emotional memory by 5-HT1B receptors involves hippocampal p11.
Topics: Animals; Annexin A2; Avoidance Learning; Depression; Disease Models, Animal; Emotions; Exploratory Behavior; Female; Genes, Reporter; Glutamic Acid; Hippocampus; Male; Memory; Mice; Mice, Inbred C57BL; Mice, Knockout; Nuclear Magnetic Resonance, Biomolecular; Phosphorylation; Presynaptic Terminals; Protein Processing, Post-Translational; Pyridines; Reaction Time; Receptor, Serotonin, 5-HT1B; Receptors, AMPA; Recombinant Fusion Proteins; S100 Proteins; Serotonin 5-HT1 Receptor Agonists; Synaptic Transmission; Transduction, Genetic | 2013 |
Glutamate hypothesis of depression and its consequences for antidepressant treatments.
Topics: Animals; Antidepressive Agents; Brain; Depression; Depressive Disorder, Major; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Molecular Targeted Therapy; Nerve Tissue Proteins; Neurons; Receptors, Glutamate; Synaptic Transmission | 2012 |
Marked reductions in visual evoked responses but not γ-aminobutyric acid concentrations or γ-band measures in remitted depression.
Topics: Adolescent; Adult; Brain; Brain Waves; Case-Control Studies; Depression; Evoked Potentials, Visual; Female; Functional Neuroimaging; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Visual Cortex | 2013 |
Glutamate release in the nucleus accumbens is involved in behavioral depression during the PORSOLT swim test.
Topics: Animals; Behavior, Animal; Depression; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Extracellular Space; Glutamic Acid; Male; Microdialysis; Microinjections; Motor Activity; Nucleus Accumbens; Physical Stimulation; Rats; Rats, Sprague-Dawley; Swimming; Tail; Time Factors; Valine | 2003 |
[RESULTS OF THE TREATMENT OF DEPRESSIVE STATES WITH GERIOCAINE (H-3), GLUTAMIC ACID AND PREPARATION PLACENTA DURING THE INVOLUTIONAL STAGE].
Topics: Depression; Depressive Disorder; Drug Therapy; Female; Glutamates; Glutamic Acid; Placenta; Pregnancy; Procaine; Tissue Extracts | 1964 |
Modulation of neuronal glutamate transporter rEAAC1 mRNA expression in rat brain by amitriptyline.
Topics: Amino Acid Transport System X-AG; Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Brain; Depression; Excitatory Amino Acid Transporter 3; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Male; Neurons; Rats; Rats, Sprague-Dawley; RNA, Messenger; Symporters | 2004 |
The metabotropic glutamate 5 receptor antagonist 3-[(2-methyl-1,3-thiazol-4-yl)ethynyl]-pyridine reduces ethanol self-administration in multiple strains of alcohol-preferring rats and regulates olfactory glutamatergic systems.
Topics: Alcohol Drinking; Alcoholism; Animals; Autoradiography; Biomarkers; Brain Chemistry; Conditioning, Operant; Depression; Drinking; Glutamic Acid; In Situ Hybridization; Male; Motor Activity; Pyridines; Rats; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Smell; Swimming; Thiazoles | 2005 |
Elevated spectroscopic glutamate/gamma-amino butyric acid in rats bred for learned helplessness.
Topics: Animals; Behavior, Animal; Brain; Depression; Disease Models, Animal; gamma-Aminobutyric Acid; Glutamic Acid; Helplessness, Learned; Magnetic Resonance Spectroscopy; Rats; Rats, Inbred Strains | 2007 |
Cerebral metabolic changes in a depression-like rat model of chronic forced swimming studied by ex vivo high resolution 1H magnetic resonance spectroscopy.
Topics: Animals; Behavior, Animal; Brain; Depression; gamma-Aminobutyric Acid; Glutamic Acid; Magnetic Resonance Spectroscopy; Male; Rats; Rats, Wistar; Stress, Physiological; Swimming | 2008 |
GABAergic modulation of learned helplessness.
Topics: Amino Acids; Animals; Avoidance Learning; Behavior, Animal; Bicuculline; Depression; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Hippocampus; Humans; Injections; Male; Rats; Rats, Inbred Strains | 1981 |
Effects of bilateral olfactory bulbectomy on N-methyl-D-aspartate receptor function: autoradiographic and behavioral studies in the rat.
Topics: Animals; Binding Sites; Brain; Denervation; Depression; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Down-Regulation; Excitatory Amino Acid Antagonists; Exploratory Behavior; gamma-Aminobutyric Acid; Glutamic Acid; Iodine Radioisotopes; Male; Neural Inhibition; Neurons; Olfactory Bulb; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate | 2001 |
Asymmetrical reductions of hippocampal NMDAR1 glutamate receptor mRNA in the psychoses.
Topics: Bipolar Disorder; Depression; Down-Regulation; Female; Functional Laterality; Glutamic Acid; Hippocampus; Humans; Male; Middle Aged; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Schizophrenia; Sex Characteristics | 2001 |