Page last updated: 2024-10-20

pyridoxal phosphate and Depression

pyridoxal phosphate has been researched along with Depression in 8 studies

Pyridoxal Phosphate: This is the active form of VITAMIN B 6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine phosphate (PYRIDOXAMINE).
pyridoxal 5'-phosphate : The monophosphate ester obtained by condensation of phosphoric acid with the primary hydroxy group of pyridoxal.

Depression: Depressive states usually of moderate intensity in contrast with MAJOR DEPRESSIVE DISORDER present in neurotic and psychotic disorders.

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19903 (37.50)18.7374
1990's0 (0.00)18.2507
2000's1 (12.50)29.6817
2010's4 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Arévalo, SP1
Scott, TM1
Falcón, LM2
Tucker, KL3
Moore, K1
Hughes, CF1
Hoey, L1
Ward, M1
Cunningham, C1
Molloy, AM1
Strain, JJ1
McCarroll, K1
Casey, MC1
Tracey, F1
Laird, E1
O'Kane, M1
McNulty, H1
Pereira, VS1
Casarotto, PC1
Hiroaki-Sato, VA1
Sartim, AG1
Guimarães, FS1
Joca, SR1
Merete, C1
Ye, X1
Lai, CQ1
Crott, JW1
Troen, AM1
Ordovas, JM1
Reynolds, RD1
Styer, DJ1
Schlichting, CL1
Nobbs, BT1
Ressler, C1
Koga, T1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Assesment of Vitamin B6 Level in Patients With Major Depressive Disorder[NCT05649293]94 participants (Anticipated)Observational2023-04-01Not yet recruiting
The Boston Puerto Rican Health Study: Center for Population Health and Health Disparities[NCT01231958]1,650 participants (Actual)Observational2004-06-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for pyridoxal phosphate and Depression

ArticleYear
Decreased vitamin B-6 status of submariners during prolonged patrol.
    The American journal of clinical nutrition, 1988, Volume: 47, Issue:3

    Topics: Adult; Depression; Humans; Male; Pyridoxal Phosphate; Pyridoxic Acid; Pyridoxine; Submarine Medicine

1988

Other Studies

7 other studies available for pyridoxal phosphate and Depression

ArticleYear
Vitamin B-6 and depressive symptomatology, over time, in older Latino adults.
    Nutritional neuroscience, 2019, Volume: 22, Issue:9

    Topics: Aged; Biomarkers; Depression; Female; Hispanic or Latino; Humans; Male; Middle Aged; Nutritional Sta

2019
B-vitamins in Relation to Depression in Older Adults Over 60 Years of Age: The Trinity Ulster Department of Agriculture (TUDA) Cohort Study.
    Journal of the American Medical Directors Association, 2019, Volume: 20, Issue:5

    Topics: Aged; Aging; Biomarkers; Cognitive Dysfunction; Cohort Studies; Cross-Sectional Studies; Depression;

2019
Antidepressant- and anticompulsive-like effects of purinergic receptor blockade: involvement of nitric oxide.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2013, Volume: 23, Issue:12

    Topics: Animals; Antidepressive Agents; Brain; Compulsive Behavior; Depression; Disease Models, Animal; Dose

2013
Vitamin B6 is associated with depressive symptomatology in Massachusetts elders.
    Journal of the American College of Nutrition, 2008, Volume: 27, Issue:3

    Topics: Aged; Cross-Sectional Studies; Depression; Diet; Dietary Supplements; Female; Hispanic or Latino; Hu

2008
The folate hydrolase 1561C>T polymorphism is associated with depressive symptoms in Puerto Rican adults.
    Psychosomatic medicine, 2011, Volume: 73, Issue:5

    Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Aged; Boston; Cross-Sectional Stud

2011
Letter: Pyridoxal phosphate status in clinical depression.
    Lancet (London, England), 1974, Mar-09, Volume: 1, Issue:7854

    Topics: Aspartate Aminotransferases; Avitaminosis; Depression; Erythrocytes; Humans; Pyridoxal Phosphate

1974
-cyanoamino acids and related nitriles as inhibitors of glutamate decarboxylase.
    Biochimica et biophysica acta, 1971, Aug-20, Volume: 242, Issue:2

    Topics: Acetates; Amino Acids; Aminobutyrates; Animals; Carbon Isotopes; Carboxy-Lyases; Chickens; Cyanides;

1971