3-(2-carboxypiperazin-4-yl)propyl-1-phosphonic acid has been researched along with Depression in 2 studies
3-(2-carboxypiperazin-4-yl)propyl-1-phosphonic acid: structure given in first source; NMDA receptor antagonist
Depression: Depressive states usually of moderate intensity in contrast with MAJOR DEPRESSIVE DISORDER present in neurotic and psychotic disorders.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The novel tricyclic antidepressant drug tianeptine had an antidepressant-like effect on a rat model of depression based on the deficit in open field activity observed on the day after 2 h restraint." | 3.68 | Effects of tianeptine on stress-induced behavioural deficits and 5-HT dependent behaviour. ( Curzon, G; Datla, KP; Sarna, GS; Whitton, PS, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Autry, AE | 1 |
| Adachi, M | 1 |
| Nosyreva, E | 1 |
| Na, ES | 1 |
| Los, MF | 1 |
| Cheng, PF | 1 |
| Kavalali, ET | 1 |
| Monteggia, LM | 1 |
| Whitton, PS | 1 |
| Sarna, GS | 1 |
| Datla, KP | 1 |
| Curzon, G | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Evaluation of the Antidepressant Effects of Nitrous Oxide in People With Major Depressive Disorder[NCT05357040] | Phase 2 | 172 participants (Anticipated) | Interventional | 2021-06-30 | Recruiting | ||
| Evaluation of the Initial Prescription of Ketamine and Milnacipran Forin Depression in Patients With a Progressive Disease[NCT02783430] | Phase 2/Phase 3 | 80 participants (Anticipated) | Interventional | 2016-09-08 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 other studies available for 3-(2-carboxypiperazin-4-yl)propyl-1-phosphonic acid and Depression
| Article | Year |
|---|---|
NMDA receptor blockade at rest triggers rapid behavioural antidepressant responses.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Brain-Derived Neurotrophic Factor; Depression; Dis | 2011 |
NMDA receptor blockade at rest triggers rapid behavioural antidepressant responses.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Brain-Derived Neurotrophic Factor; Depression; Dis | 2011 |
NMDA receptor blockade at rest triggers rapid behavioural antidepressant responses.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Brain-Derived Neurotrophic Factor; Depression; Dis | 2011 |
NMDA receptor blockade at rest triggers rapid behavioural antidepressant responses.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Brain-Derived Neurotrophic Factor; Depression; Dis | 2011 |
Effects of tianeptine on stress-induced behavioural deficits and 5-HT dependent behaviour.
Topics: Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Depression; Disease Models, Animal; Mal | 1991 |