acetaminophen has been researched along with Depression in 34 studies
Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.
Depression: Depressive states usually of moderate intensity in contrast with MAJOR DEPRESSIVE DISORDER present in neurotic and psychotic disorders.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This investigation found that tramadol-acetaminophen is effective for reducing LBP and provided a prophylactic antidepressant effect in chronic LBP patients with depression." | 9.20 | Efficacy of tramadol-acetaminophen tablets in low back pain patients with depression. ( Ozaki, T; Tanaka, M; Tetsunaga, T, 2015) |
| "The effect of the selective serotonin reuptake inhibitor citalopram was studied in a randomized, double-blind, placebo-controlled, 4-month trial in patients with the fibromyalgia syndrome (FMS) who all fulfilled the American College of Rheumatology criteria." | 9.09 | Citalopram in patients with fibromyalgia--a randomized, double-blind, placebo-controlled study. ( Anderberg, UM; Marteinsdottir, I; von Knorring, L, 2000) |
| "Analgesic treatment did not reduce depression while placebo appeared to improve depressive symptoms significantly by comparison, possibly owing to the adverse effects of active buprenorphine." | 5.27 | Efficacy and Safety of Analgesic Treatment for Depression in People with Advanced Dementia: Randomised, Multicentre, Double-Blind, Placebo-Controlled Trial (DEP.PAIN.DEM). ( Aarsland, D; Ballard, C; Erdal, A; Flo, E; Husebo, BS; Slettebo, DD, 2018) |
| "This investigation found that tramadol-acetaminophen is effective for reducing LBP and provided a prophylactic antidepressant effect in chronic LBP patients with depression." | 5.20 | Efficacy of tramadol-acetaminophen tablets in low back pain patients with depression. ( Ozaki, T; Tanaka, M; Tetsunaga, T, 2015) |
| "The effect of the selective serotonin reuptake inhibitor citalopram was studied in a randomized, double-blind, placebo-controlled, 4-month trial in patients with the fibromyalgia syndrome (FMS) who all fulfilled the American College of Rheumatology criteria." | 5.09 | Citalopram in patients with fibromyalgia--a randomized, double-blind, placebo-controlled study. ( Anderberg, UM; Marteinsdottir, I; von Knorring, L, 2000) |
| " Although a lymphocyte stimulation test was positive only for acetaminophen, he took other agents including carbamazepine for his depression." | 3.76 | Toxic epidermal necrolysis with prominent facial pustules: a case with reactivation of human herpesvirus 7. ( Honma, M; Iinuma, S; Iizuka, H; Ishida-Yamamoto, A; Komatsu, S; Shibuya, T; Takahashi, I; Tobisawa, S, 2010) |
| "Un(der)diagnosed and un(der)treated pain is a serious and frequent problem in persons with dementia." | 2.87 | Quality of life and paracetamol in advanced dementia (Q-PID): protocol of a randomised double-blind placebo-controlled crossover trial. ( Achterberg, WP; Caljouw, MAA; Gussekloo, J; Husebo, BS; van Dam, PH, 2018) |
| "A 14-year-old girl with systemic lupus erythematosus presented with a mixed overdose of paracetamol, ibuprofen and azathioprine (1500 mg) following a deliberate self-harm attempt." | 2.49 | Intentional overdose of azathioprine in a patient with systemic lupus erythematosus. ( Khan, AM; Mahmood, K; Martin, K; Ramanan, AV, 2013) |
| "The severity of poisoning is assessed by gathering all information about the patient, the drug(s) ingested, the circumstances of ingestion, and any other substances ingested at the same time." | 2.46 | Acute poisoning following ingestion of medicines: initial management. How to treat life-threatening complications and to evaluate the risk of delayed effects and psychological distress. ( , 2010) |
| "Legg-Calvé-Perthes disease (LCPD) and slipped capital femoral epiphysis (SCFE) can result in painful deformation of the hip joint with impaired range of motion and early development of secondary osteoarthritis." | 1.72 | Pediatric Hip Disease Increases the Risk for Opioid Use in Adulthood: Long-term Burden of Pain and Depression. ( Hailer, YD; Wadström, MG, 2022) |
| "The Beck Depression Inventory, the ID Migraine™ screening tool, and the criteria of the International Headache Society were used to investigate the depressive symptoms and headache types." | 1.51 | Migraine, tension-type headache, and depression among Saudi female students in Taif University. ( Desouky, DE; Taha, AA; Zaid, HA, 2019) |
| "Although daytime sleepiness occurred in a large number of residents, especially those with dementia, this sleepiness was not necessarily associated with use of opioids." | 1.42 | Analgesic Use and Daytime Sleepiness in Residents With and Without Dementia in Residential Aged Care Facilities. ( Bell, JS; Emery, T; Hilmer, SN; Hughes, JM; Ilomäki, J; Jones, MJ; Moawad, S; Quirke, T; Robson, L; Tan, EC; Visvanathan, R; Vitry, AI, 2015) |
| "Sertraline (SSRI) was the most frequently prescribed antidepressant." | 1.36 | A cross-sectional observation of the factors associated with deliberate self-poisoning with acetaminophen: impact of gender differences and psychiatric intervention. ( Al-Jabi, SW; Awang, R; Sulaiman, SA; Zyoud, SH, 2010) |
| "The patient developed acute renal failure, and also had fever and unilateral ear inflammation." | 1.35 | Acute renal failure following detergent ingestion. ( Lim, YC, 2009) |
| "Anxiety and depression are often also present." | 1.35 | Fibromyalgia: poorly understood; treatments are disappointing. ( , 2009) |
| "The SMILE study was conducted among migraine patients consulting in primary care in France." | 1.35 | SMILE: first observational prospective cohort study of migraine in primary care in France. Description of methods and study population. ( Géraud, G; Joubert, JM; Lantéri-Minet, M; Lucas, C; Mekies, C; Radat, F; Valade, D; Vives, E, 2008) |
| "The intensity of the postoperative pain was measured on a visual analog scale (VAS); measurements were noted up to 24 hours postop then at one month." | 1.34 | [Can the postoperative pain level be predicted preoperatively?]. ( Blay, M; Boileau, P; Carles, M; Dambreville, A; Hovorka, I, 2007) |
| "Adjustment disorder was the most common diagnosis followed by depression." | 1.30 | Overdose among youth in Bahrain: psycho-social characteristics, contact with helping agencies and problems. ( al-Ansari, AM; Buzaboon, B; Hamadeh, RR; Marhoon, H; Matar, AM; Raees, AG, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (2.94) | 18.7374 |
| 1990's | 2 (5.88) | 18.2507 |
| 2000's | 12 (35.29) | 29.6817 |
| 2010's | 16 (47.06) | 24.3611 |
| 2020's | 3 (8.82) | 2.80 |
| Authors | Studies |
|---|---|
| Wadström, MG | 1 |
| Hailer, YD | 1 |
| Qutob, HMH | 1 |
| Saad, RA | 1 |
| Bali, H | 1 |
| Osailan, A | 1 |
| Jaber, J | 1 |
| Alzahrani, E | 1 |
| Alyami, J | 1 |
| Elsayed, H | 1 |
| Alserihi, R | 1 |
| Shaikhomar, OA | 1 |
| Divya, KM | 1 |
| Savitha, DP | 1 |
| Krishna, GA | 1 |
| Dhanya, TM | 1 |
| Mohanan, PV | 1 |
| Shah, SF | 1 |
| Jafry, AT | 1 |
| Hussain, G | 1 |
| Kazim, AH | 1 |
| Ali, M | 1 |
| Rivani, E | 1 |
| Endraswari, PD | 1 |
| Widodo, ADW | 1 |
| Khalil, MR | 1 |
| Guldberg, R | 1 |
| Nørgård, BM | 1 |
| Uldbjerg, N | 1 |
| Wehberg, S | 1 |
| Fowobaje, KR | 1 |
| Mashood, LO | 1 |
| Ekholuenetale, M | 1 |
| Ibidoja, OJ | 1 |
| Romagnoli, A | 1 |
| D'Agostino, M | 1 |
| Pavoni, E | 1 |
| Ardiccioni, C | 1 |
| Motta, S | 1 |
| Crippa, P | 1 |
| Biagetti, G | 1 |
| Notarstefano, V | 1 |
| Rexha, J | 1 |
| Perta, N | 1 |
| Barocci, S | 1 |
| Costabile, BK | 1 |
| Colasurdo, G | 1 |
| Caucci, S | 1 |
| Mencarelli, D | 1 |
| Turchetti, C | 1 |
| Farina, M | 1 |
| Pierantoni, L | 1 |
| La Teana, A | 1 |
| Al Hadi, R | 1 |
| Cicconardi, F | 1 |
| Chinappi, M | 1 |
| Trucchi, E | 1 |
| Mancia, F | 1 |
| Menzo, S | 1 |
| Morozzo Della Rocca, B | 1 |
| D'Annessa, I | 1 |
| Di Marino, D | 1 |
| Choya, A | 1 |
| de Rivas, B | 1 |
| Gutiérrez-Ortiz, JI | 1 |
| López-Fonseca, R | 1 |
| Xu, S | 1 |
| Cheng, B | 1 |
| Huang, Z | 1 |
| Liu, T | 1 |
| Li, Y | 1 |
| Jiang, L | 1 |
| Guo, W | 1 |
| Xiong, J | 1 |
| Amirazodi, M | 1 |
| Daryanoosh, F | 1 |
| Mehrabi, A | 1 |
| Gaeini, A | 1 |
| Koushkie Jahromi, M | 1 |
| Salesi, M | 1 |
| Zarifkar, AH | 1 |
| Studeny, P | 1 |
| Netukova, M | 1 |
| Nemcokova, M | 1 |
| Klimesova, YM | 1 |
| Krizova, D | 1 |
| Kang, H | 1 |
| Tao, Y | 1 |
| Zhang, Q | 1 |
| Sha, D | 1 |
| Chen, Y | 1 |
| Yao, J | 1 |
| Gao, Y | 1 |
| Liu, J | 1 |
| Ji, L | 1 |
| Shi, P | 1 |
| Shi, C | 1 |
| Wu, YL | 1 |
| Wright, AI | 1 |
| M El-Metwaly, N | 1 |
| A Katouah, H | 1 |
| El-Desouky, MG | 1 |
| El-Bindary, AA | 1 |
| El-Bindary, MA | 1 |
| Kostakis, ID | 1 |
| Raptis, DA | 1 |
| Davidson, BR | 1 |
| Iype, S | 1 |
| Nasralla, D | 1 |
| Imber, C | 1 |
| Sharma, D | 1 |
| Pissanou, T | 1 |
| Pollok, JM | 1 |
| Hughes, AM | 1 |
| Sanderson, E | 1 |
| Morris, T | 1 |
| Ayorech, Z | 1 |
| Tesli, M | 1 |
| Ask, H | 1 |
| Reichborn-Kjennerud, T | 1 |
| Andreassen, OA | 1 |
| Magnus, P | 1 |
| Helgeland, Ø | 1 |
| Johansson, S | 1 |
| Njølstad, P | 1 |
| Davey Smith, G | 1 |
| Havdahl, A | 1 |
| Howe, LD | 1 |
| Davies, NM | 1 |
| Amrillah, T | 1 |
| Prasetio, A | 1 |
| Supandi, AR | 1 |
| Sidiq, DH | 1 |
| Putra, FS | 1 |
| Nugroho, MA | 1 |
| Salsabilla, Z | 1 |
| Azmi, R | 1 |
| Grammatikopoulos, P | 1 |
| Bouloumis, T | 1 |
| Steinhauer, S | 1 |
| Mironov, VS | 2 |
| Bazhenova, TA | 2 |
| Manakin, YV | 2 |
| Yagubskii, EB | 2 |
| Yakushev, IA | 1 |
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| Simonov, SV | 1 |
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| Yang, H | 1 |
| Zheng, J | 1 |
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| Ghaemi, R | 1 |
| Acker, M | 1 |
| Stosic, A | 1 |
| Jacobs, R | 1 |
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| Razzo, BM | 1 |
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| Zhou, H | 1 |
| Deng, Z | 1 |
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| Ong, SP | 1 |
| Wang, C | 1 |
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| Whittingham, MS | 1 |
| Zhou, G | 1 |
| Maemura, R | 1 |
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| Muramatsu, H | 1 |
| Takahashi, Y | 1 |
| Yirgu, A | 1 |
| Mekonnen, Y | 1 |
| Eyado, A | 1 |
| Staropoli, A | 1 |
| Vinale, F | 1 |
| Zac, J | 1 |
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| Pérez-Padilla, R | 1 |
| Remigio-Luna, A | 1 |
| Guzmán-Boulloud, N | 1 |
| Gochicoa-Rangel, L | 1 |
| Guzmán-Valderrábano, C | 1 |
| Thirión-Romero, I | 1 |
| Statsenko, ME | 1 |
| Turkina, SV | 1 |
| Barantsevich, ER | 1 |
| Karakulova, YV | 1 |
| Baranova, NS | 1 |
| Morzhukhina, MV | 1 |
| Wang, Q | 1 |
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| Chen, C | 1 |
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| Hoekstra, PJ | 1 |
| Dietrich, A | 1 |
| Erdal, A | 1 |
| Flo, E | 1 |
| Aarsland, D | 1 |
| Ballard, C | 1 |
| Slettebo, DD | 1 |
| Husebo, BS | 2 |
| Perrin, G | 1 |
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| Pannier, B | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Efficacy of Pain Treatment on Depression in Patients With Dementia. A Randomized Clinical Trial.[NCT02267057] | Phase 4 | 163 participants (Actual) | Interventional | 2014-08-31 | Completed | ||
| Evaluation of the Efficiency of a Therapeutic Education Program in Standardized Thermal Cure for Fibromyalgia Patients[NCT02406313] | 152 participants (Actual) | Interventional | 2015-03-31 | Active, not recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for acetaminophen and Depression
| Article | Year |
|---|---|
Impact of dexamethasone and tocilizumab on hematological parameters in COVID-19 patients with chronic disease.
Topics: Acetaminophen; Acetylcarnitine; Acetylcholinesterase; Acids; Acinetobacter baumannii; Acinetobacter | 2022 |
Dipyridamole and paracetamol overdose resulting in multi-organ failure.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Depression; Dipyridamole; Drug Overdose; Female; Hospitaliz | 2013 |
Intentional overdose of azathioprine in a patient with systemic lupus erythematosus.
Topics: Acetaminophen; Adolescent; Affective Disorders, Psychotic; Anti-Inflammatory Agents, Non-Steroidal; | 2013 |
Acute poisoning following ingestion of medicines: initial management. How to treat life-threatening complications and to evaluate the risk of delayed effects and psychological distress.
Topics: Acetaminophen; Acetylcysteine; Acute Disease; Charcoal; Depression; Gastric Lavage; Humans; Poisonin | 2010 |
6 trials available for acetaminophen and Depression
| Article | Year |
|---|---|
Impact of dexamethasone and tocilizumab on hematological parameters in COVID-19 patients with chronic disease.
Topics: Acetaminophen; Acetylcarnitine; Acetylcholinesterase; Acids; Acinetobacter baumannii; Acinetobacter | 2022 |
Efficacy and Safety of Analgesic Treatment for Depression in People with Advanced Dementia: Randomised, Multicentre, Double-Blind, Placebo-Controlled Trial (DEP.PAIN.DEM).
Topics: Acetaminophen; Administration, Cutaneous; Aged, 80 and over; Analgesics; Buprenorphine; Chronic Pain | 2018 |
Quality of life and paracetamol in advanced dementia (Q-PID): protocol of a randomised double-blind placebo-controlled crossover trial.
Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Cross-Over Studies; Dementia; Depression; Double-Blin | 2018 |
Efficacy of tramadol-acetaminophen tablets in low back pain patients with depression.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-In | 2015 |
The associations between severity of early postoperative pain, chronic postsurgical pain and plasma concentration of stable nitric oxide products after breast surgery.
Topics: Acetaminophen; Adult; Aged; Analgesia; Anxiety; Breast Neoplasms; Bupivacaine; Celecoxib; Chronic Di | 2006 |
Citalopram in patients with fibromyalgia--a randomized, double-blind, placebo-controlled study.
Topics: Acetaminophen; Activities of Daily Living; Adult; Analgesics, Non-Narcotic; Antidepressive Agents; C | 2000 |
25 other studies available for acetaminophen and Depression
| Article | Year |
|---|---|
Pediatric Hip Disease Increases the Risk for Opioid Use in Adulthood: Long-term Burden of Pain and Depression.
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Opioid; Anti-Inflammatory Agents; Antidepressive Agent | 2022 |
Zinc, but not paracetamol, prevents depressive-like behavior and sickness behavior, and inhibits interferon-gamma and astrogliosis in rats.
Topics: Acetaminophen; Animals; Behavior, Animal; Depression; Disease Models, Animal; Gliosis; Illness Behav | 2020 |
Pregnancy risk factors in relation to oppositional-defiant and conduct disorder symptoms in the Avon Longitudinal Study of Parents and Children.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Attention Deficit and Disruptive Behavior Disorders; Child; | 2018 |
Evaluation of exposure to effervescent drugs in a large health check-up population in France: a cross-sectional study.
Topics: Acetaminophen; Adult; Antipyretics; Aspirin; Betaine; Body Mass Index; Cross-Sectional Studies; Depr | 2018 |
Migraine, tension-type headache, and depression among Saudi female students in Taif University.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anxiety; Comorbidity; Cross-Sectional Studies; Depre | 2019 |
Prenatal paracetamol exposure and child neurodevelopment: a sibling-controlled cohort study.
Topics: Acetaminophen; Aggression; Analgesics, Non-Narcotic; Anxiety; Case-Control Studies; Child Developmen | 2013 |
Paracetamol potentiates the antidepressant-like and anticompulsive-like effects of fluoxetine.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Arachidonic Acids; Compulsive Behavior; Depression | 2015 |
Inflammation and depression: combined use of selective serotonin reuptake inhibitors and NSAIDs or paracetamol and psychiatric outcomes.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; | 2015 |
Analgesic Use and Daytime Sleepiness in Residents With and Without Dementia in Residential Aged Care Facilities.
Topics: Acetaminophen; Aged, 80 and over; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Ster | 2015 |
Acute renal failure following detergent ingestion.
Topics: Acetaminophen; Acute Kidney Injury; Adult; Depression; Detergents; Eating; Female; Fluoxetine; Human | 2009 |
Fibromyalgia: poorly understood; treatments are disappointing.
Topics: Acetaminophen; Acupuncture Therapy; Amines; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Ant | 2009 |
Outcomes of liver transplantation for paracetamol (acetaminophen)-induced hepatic failure.
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Depression; Female; Follow-Up Studies; H | 2009 |
Prediction of postoperative pain after mandibular third molar surgery.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anxiety; Attitude; Depression; Eating; Female; Follo | 2010 |
A cross-sectional observation of the factors associated with deliberate self-poisoning with acetaminophen: impact of gender differences and psychiatric intervention.
Topics: Acetaminophen; Adolescent; Adult; Age Factors; Antidepressive Agents; Cross-Sectional Studies; Depre | 2010 |
Toxic epidermal necrolysis with prominent facial pustules: a case with reactivation of human herpesvirus 7.
Topics: Acetaminophen; Acute Generalized Exanthematous Pustulosis; Adult; Anti-Inflammatory Agents; Antidepr | 2010 |
Severe manifestations of coricidin intoxication.
Topics: Acetaminophen; Adolescent; Antidepressive Agents; Chemical and Drug Induced Liver Injury; Chlorpheni | 2003 |
Botulinum toxin A for the treatment of greater occipital neuralgia and trigeminal neuralgia: a case report with pathophysiological considerations.
Topics: Acetaminophen; Adult; Analgesics; Anxiety; Aspirin; Botulinum Toxins, Type A; Caffeine; Colitis, Ulc | 2006 |
Parkinsonism-hyperpyrexia syndrome: the role of electroconvulsive therapy.
Topics: Acetaminophen; Acyclovir; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Anxiety Agents; Anti-Ba | 2006 |
SMILE: first observational prospective cohort study of migraine in primary care in France. Description of methods and study population.
Topics: Acetaminophen; Adaptation, Psychological; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, | 2008 |
[Can the postoperative pain level be predicted preoperatively?].
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Anx | 2007 |
Overdose among youth in Bahrain: psycho-social characteristics, contact with helping agencies and problems.
Topics: Acetaminophen; Adjustment Disorders; Adolescent; Adult; Analgesics, Non-Narcotic; Attitude to Health | 1997 |
Paracetamol hepatotoxicity and alcohol consumption in deliberate and accidental overdose.
Topics: Acetaminophen; Adolescent; Adult; Aged; Alcohol Drinking; Analgesics, Non-Narcotic; Chemical and Dru | 2000 |
Chronic pain, bereavement and overdose in a depressed elderly woman.
Topics: Acetaminophen; Aged; Aged, 80 and over; Aging; Aortic Aneurysm, Thoracic; Aspirin; Back Pain; Bereav | 2002 |
Use and abuse of non-narcotic analgesics.
Topics: Acetaminophen; Analgesics; Depression; Female; Gender Identity; Humans; Personality; Personality Inv | 1978 |
Failure to monitor patient: deplorable nursing care. Case in point: Harrington v. Rush-Presbyterian-St. Luke's (569 N.E. 2d 15--IL (1990)).
Topics: Accidents, Traffic; Acetaminophen; Amputation, Surgical; Death; Depression; Dextropropoxyphene; Drug | 1991 |