Page last updated: 2024-10-22

arecoline and Depression

arecoline has been researched along with Depression in 3 studies

Arecoline: An alkaloid obtained from the betel nut (Areca catechu), fruit of a palm tree. It is an agonist at both muscarinic and nicotinic acetylcholine receptors. It is used in the form of various salts as a ganglionic stimulant, a parasympathomimetic, and a vermifuge, especially in veterinary practice. It has been used as a euphoriant in the Pacific Islands.
arecoline : A tetrahydropyridine that is 1,2,5,6-tetrahydropyridine with a methyl group at position 1, and a methoxycarbonyl group at position 3. An alkaloid found in the areca nut, it acts as an agonist of muscarinic acetylcholine.

Depression: Depressive states usually of moderate intensity in contrast with MAJOR DEPRESSIVE DISORDER present in neurotic and psychotic disorders.

Research Excerpts

ExcerptRelevanceReference
"Two lines of rats that were selectively bred to vary in their sensitivity to the anticholinesterase DFP exhibited different degrees of behavioral depression after injection of the muscarinic agonist arecoline (2 mg/kg)."3.67Selective breeding for increased cholinergic function: development of a new animal model of depression. ( Overstreet, DH, 1986)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19901 (33.33)18.7374
1990's1 (33.33)18.2507
2000's0 (0.00)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Iezhitsa, IN1
Spasov, AA1
Kharitonova, MV1
Kravchenko, MS1
Chau, D1
Rada, PV1
Kosloff, RA1
Hoebel, BG1
Overstreet, DH1

Other Studies

3 other studies available for arecoline and Depression

ArticleYear
Effect of magnesium chloride on psychomotor activity, emotional status, and acute behavioural responses to clonidine, d-amphetamine, arecoline, nicotine, apomorphine, and L-5-hydroxytryptophan.
    Nutritional neuroscience, 2011, Volume: 14, Issue:1

    Topics: 5-Hydroxytryptophan; Amphetamine; Animals; Anxiety; Apomorphine; Arecoline; Clonidine; Depression; D

2011
Cholinergic, M1 receptors in the nucleus accumbens mediate behavioral depression. A possible downstream target for fluoxetine.
    Annals of the New York Academy of Sciences, 1999, Jun-29, Volume: 877

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acetylcholine; Animals; Arecoline; Depression; Female; Fluox

1999
Selective breeding for increased cholinergic function: development of a new animal model of depression.
    Biological psychiatry, 1986, Volume: 21, Issue:1

    Topics: Animals; Arecoline; Breeding; Depression; Depressive Disorder; Disease Models, Animal; Electroshock;

1986