Page last updated: 2024-11-08

pentylenetetrazole and Depression

pentylenetetrazole has been researched along with Depression in 44 studies

Pentylenetetrazole: A pharmaceutical agent that displays activity as a central nervous system and respiratory stimulant. It is considered a non-competitive GAMMA-AMINOBUTYRIC ACID antagonist. Pentylenetetrazole has been used experimentally to study seizure phenomenon and to identify pharmaceuticals that may control seizure susceptibility.
pentetrazol : An organic heterobicyclic compound that is 1H-tetrazole in which the hydrogens at positions 1 and 5 are replaced by a pentane-1,5-diyl group. A central and respiratory stimulant, it was formerly used for the treatment of cough and other respiratory tract disorders, cardiovascular disorders including hypotension, and pruritis.

Depression: Depressive states usually of moderate intensity in contrast with MAJOR DEPRESSIVE DISORDER present in neurotic and psychotic disorders.

Research Excerpts

ExcerptRelevanceReference
"The effects of rapamycin on anxiety and depression caused by pentylenetetrazole (PTZ) in the rat and possible underlying mechanisms were evaluated."8.02Rapamycin attenuates depression and anxiety-like behaviors through modulation of the NLRP3 pathway in pentylenetetrazole-kindled male Wistar rats. ( Aghaie, F; Hosseini, A; Moradifar, F, 2021)
"We found that pterostilbene at a dose of 200 mg/kg considerably reduced seizure activity but did not influence the locomotor activity and depression- and anxiety-like behavior in the PTZ-kindled mice."8.02Anticonvulsant effect of pterostilbene and its influence on the anxiety- and depression-like behavior in the pentetrazol-kindled mice: behavioral, biochemical, and molecular studies. ( Nalepa, I; Nieoczym, D; Pieróg, M; Przejczowska-Pomierny, K; Socała, K; Szafarz, M; Wlaź, P; Wyska, E; Zelek-Molik, A, 2021)
"Epilepsy was induced in rats by injecting Pentylenetetrazole at 35 mg/kg every other day."7.96Glutamatergic pathway in depressive-like behavior associated with pentylenetetrazole rat model of epilepsy with history of prolonged febrile seizures. ( Alese, OO; Mabandla, MV; Mkhize, NV; Ngoupaye, GT; Rakgantsho, C; Zulu, S, 2020)
" This study was envisaged to evaluate the ameliorative effect of Curcumin on depression like behavior and cognitive impairment observed in pentylenetetrazole kindled animals."7.79Ameliorative effect of Curcumin on seizure severity, depression like behavior, learning and memory deficit in post-pentylenetetrazole-kindled mice. ( Choudhary, KM; Goel, RK; Mishra, A; Poroikov, VV, 2013)
" perforatum was compared with standard antidepressants using animal models of depression such as forced swim test (FST), yohimbine induced lethality test, pnetylenetetrazole (PTZ) induced convulsion and locomotor activity tests."7.79Behavioral profile of Hypericum perforatum (St. John's Wort) extract. A comparison with standard antidepressants in animal models of depression. ( Bukhari, IA; Dar, A, 2013)
"The intensity of convulsion was scored according to a seven-point scale ranging from stage 0-7."5.62Creatine attenuates seizure severity, anxiety and depressive-like behaviors in pentylenetetrazole kindled mice. ( Abiola, AL; Akhigbemen, AM; Chinazamoku, O; Igbe, I; Ogundepo, GE; Okwuofu, EO; Ozolua, RI, 2021)
"Epilepsy is fourth most common neurological disorders associated with depression and cognitive deficits."5.46Agmatine for combined treatment of epilepsy, depression and cognitive impairment in chronic epileptic animals. ( Bagga, N; Gawande, DY; Goel, RK; Kaur, A; Kaur, N; Singh, T, 2017)
"for 15 days."5.46Ferulic Acid Supplementation for Management of Depression in Epilepsy. ( Goel, RK; Kaur, T; Singh, T, 2017)
"Depression was evaluated in all experimental groups using the tail suspension and sucrose preference test on days 1, 5, 10 and 15, 2 h after pentylenetetrazole challenge."5.46Adjuvant quercetin therapy for combined treatment of epilepsy and comorbid depression. ( Goel, RK; Kaur, T; Singh, T, 2017)
"Pretreatment with spermine, considerably, reversed the PTZ induced alterations."5.46Protective effect of spermine against pentylenetetrazole kindling epilepsy induced comorbidities in mice. ( Kumar, M; Kumar, P, 2017)
"The effects of rapamycin on anxiety and depression caused by pentylenetetrazole (PTZ) in the rat and possible underlying mechanisms were evaluated."4.02Rapamycin attenuates depression and anxiety-like behaviors through modulation of the NLRP3 pathway in pentylenetetrazole-kindled male Wistar rats. ( Aghaie, F; Hosseini, A; Moradifar, F, 2021)
"We found that pterostilbene at a dose of 200 mg/kg considerably reduced seizure activity but did not influence the locomotor activity and depression- and anxiety-like behavior in the PTZ-kindled mice."4.02Anticonvulsant effect of pterostilbene and its influence on the anxiety- and depression-like behavior in the pentetrazol-kindled mice: behavioral, biochemical, and molecular studies. ( Nalepa, I; Nieoczym, D; Pieróg, M; Przejczowska-Pomierny, K; Socała, K; Szafarz, M; Wlaź, P; Wyska, E; Zelek-Molik, A, 2021)
" Epilepsy-associated comorbid depression was evaluated by tail suspension test, sucrose preference test, and plasma corticosterone levels, whereas epilepsy-associated memory deficit condition was assessed by step-through paradigm, Morris water maze, and nitrite levels."3.96Exploring the ameliorative role of α7 neuronal nicotinic acetylcholine receptor modulation in epilepsy and associated comorbidities in post-PTZ-kindled mice. ( Goel, RK; Kaur, S; Sharma, NK, 2020)
"Epilepsy was induced in rats by injecting Pentylenetetrazole at 35 mg/kg every other day."3.96Glutamatergic pathway in depressive-like behavior associated with pentylenetetrazole rat model of epilepsy with history of prolonged febrile seizures. ( Alese, OO; Mabandla, MV; Mkhize, NV; Ngoupaye, GT; Rakgantsho, C; Zulu, S, 2020)
"In view of well-evidenced antiepileptic effects of melatonin and few reports of anticonvulsant action of agomelatine, the present study investigated whether agomelatine protects against pentylenetetrazole (PTZ)-induced kindling in mice and kindling-associated oxidative stress, depression, and impairment of spatial memory."3.85Effects of agomelatine on pentylenetetrazole-induced kindling, kindling-associated oxidative stress, and behavioral despair in mice and modulation of its actions by luzindole and 1-(m-chlorophenyl) piperazine. ( Agarwal, NB; Azim, MS; Vohora, D, 2017)
" Owing to the major role of neuronal nitric oxide synthase (nNOS) in brain and ineffectiveness of antiepileptic drugs (AEDs) in restoring nitrosative stress, the present study was envisaged to evaluate the adjuvant nNOS inhibitor, 7-nitroindazole (7-NI) with valproic acid for combined treatment of epilepsy and associated depression."3.85Adjuvant neuronal nitric oxide synthase inhibition for combined treatment of epilepsy and comorbid depression. ( Goel, RK; Singh, T, 2017)
"The present study aimed to develop a neurochemistry-based single or adjuvant therapy approach for comprehensive management of epilepsy and associated depression employing pentylenetetrazole-kindled animals."3.83Evidence in support of using a neurochemistry approach to identify therapy for both epilepsy and associated depression. ( Goel, RK; Singh, T, 2016)
"Hence, this study was conducted to evaluate the effects of an active fraction extracted from the leaves of Crinum jagus against seizures, depression-like behaviour and oxidative stress in pentylenetetrazole (PTZ)-induced kindling in mice."3.83Anticonvulsant activity of an active fraction extracted from Crinum jagus L. (Amaryllidaceae), and its possible effects on fully kindled seizures, depression-like behaviour and oxidative stress in experimental rodent models. ( Dabole, B; De Waard, M; Menanga, JR; Taiwe, GS; Tchoya, TB, 2016)
" This study was envisaged to evaluate the ameliorative effect of Curcumin on depression like behavior and cognitive impairment observed in pentylenetetrazole kindled animals."3.79Ameliorative effect of Curcumin on seizure severity, depression like behavior, learning and memory deficit in post-pentylenetetrazole-kindled mice. ( Choudhary, KM; Goel, RK; Mishra, A; Poroikov, VV, 2013)
" perforatum was compared with standard antidepressants using animal models of depression such as forced swim test (FST), yohimbine induced lethality test, pnetylenetetrazole (PTZ) induced convulsion and locomotor activity tests."3.79Behavioral profile of Hypericum perforatum (St. John's Wort) extract. A comparison with standard antidepressants in animal models of depression. ( Bukhari, IA; Dar, A, 2013)
"The intensity of convulsion was scored according to a seven-point scale ranging from stage 0-7."1.62Creatine attenuates seizure severity, anxiety and depressive-like behaviors in pentylenetetrazole kindled mice. ( Abiola, AL; Akhigbemen, AM; Chinazamoku, O; Igbe, I; Ogundepo, GE; Okwuofu, EO; Ozolua, RI, 2021)
"Epilepsy is fourth most common neurological disorders associated with depression and cognitive deficits."1.46Agmatine for combined treatment of epilepsy, depression and cognitive impairment in chronic epileptic animals. ( Bagga, N; Gawande, DY; Goel, RK; Kaur, A; Kaur, N; Singh, T, 2017)
"for 15 days."1.46Ferulic Acid Supplementation for Management of Depression in Epilepsy. ( Goel, RK; Kaur, T; Singh, T, 2017)
"Depression was evaluated in all experimental groups using the tail suspension and sucrose preference test on days 1, 5, 10 and 15, 2 h after pentylenetetrazole challenge."1.46Adjuvant quercetin therapy for combined treatment of epilepsy and comorbid depression. ( Goel, RK; Kaur, T; Singh, T, 2017)
"Pretreatment with spermine, considerably, reversed the PTZ induced alterations."1.46Protective effect of spermine against pentylenetetrazole kindling epilepsy induced comorbidities in mice. ( Kumar, M; Kumar, P, 2017)
"Finally, we showed that kainate induced seizures and glycemia were not modified by spadin treatments."1.38Spadin as a new antidepressant: absence of TREK-1-related side effects. ( Borsotto, M; Coppola, T; Gandin, C; Heurteaux, C; Labbal, F; Mazella, J; Moha Ou Maati, H; Veyssiere, J; Widmann, C, 2012)
"(Passifloraceae) has been used for the treatment of epilepsy in several traditional systems of medicine."1.38Dual protective effect of Passiflora incarnata in epilepsy and associated post-ictal depression. ( Goel, RK; Singh, B; Singh, D, 2012)

Research

Studies (44)

TimeframeStudies, this research(%)All Research%
pre-199018 (40.91)18.7374
1990's0 (0.00)18.2507
2000's1 (2.27)29.6817
2010's16 (36.36)24.3611
2020's9 (20.45)2.80

Authors

AuthorsStudies
Wang, X1
Xiao, A1
Yang, Y1
Zhao, Y1
Wang, CC1
Wang, Y1
Han, J1
Wang, Z1
Wen, M1
Sharma, NK1
Kaur, S1
Goel, RK12
Alese, OO1
Ngoupaye, GT1
Rakgantsho, C1
Mkhize, NV1
Zulu, S1
Mabandla, MV1
Nesci, V1
Russo, E1
Arcidiacono, B1
Citraro, R1
Tallarico, M1
Constanti, A1
Brunetti, A1
De Sarro, G1
Leo, A1
Polish, N1
Nesterkina, M1
Marintsova, N1
Karkhut, A1
Kravchenko, I1
Novikov, V1
Khairulin, A1
Okwuofu, EO1
Ogundepo, GE1
Akhigbemen, AM1
Abiola, AL1
Ozolua, RI1
Igbe, I1
Chinazamoku, O1
Aghaie, F1
Moradifar, F1
Hosseini, A1
Nieoczym, D1
Socała, K1
Zelek-Molik, A1
Pieróg, M1
Przejczowska-Pomierny, K1
Szafarz, M1
Wyska, E1
Nalepa, I1
Wlaź, P1
Singh, T6
Mishra, A3
Azim, MS1
Agarwal, NB1
Vohora, D1
Bagga, N1
Kaur, A1
Kaur, N1
Gawande, DY1
Kaur, T2
Choudhary, KM1
Poroikov, VV1
Bukhari, IA1
Dar, A1
Pahwa, P2
Kaur, D1
Taiwe, GS1
Tchoya, TB1
Menanga, JR1
Dabole, B1
De Waard, M1
Kumar, M1
Kumar, P1
BOOKER, WM2
FRENCH, DM2
CARLSSON, A1
THEANDER, G1
Moha Ou Maati, H1
Veyssiere, J1
Labbal, F1
Coppola, T1
Gandin, C1
Widmann, C1
Mazella, J1
Heurteaux, C1
Borsotto, M1
Takechi, K1
Suemaru, K1
Kawasaki, H1
Araki, H1
Singh, B1
Singh, D2
SCHERRER, P1
LECLERC, J1
LATOUCHE, M1
LARSON, E1
WYNN, MF1
ADAMS, JP1
TEBROCK, HE1
YOUNG, W1
O'DONNELL, W1
KAUFMAN, M1
VIDAL-TEIXIDOR, R1
LISS, L1
SOLZE, DA1
FISCHER, R1
KRAEMER, R1
MELLINGHOFF, ML1
MOLANO, PA1
RHODES, C1
Cao, BJ1
Li, Y1
Cole, JO1
Stotsky, BA1
Ferrini, R1
Miragoli, G1
Croce, G1
Fink, M2
Abrams, R1
Neki, JS1
Kishore, B1
Winters, WD1
Pelczarska, A1

Reviews

2 reviews available for pentylenetetrazole and Depression

ArticleYear
PTZ kindling model for epileptogenesis, refractory epilepsy, and associated comorbidities: relevance and reliability.
    Metabolic brain disease, 2021, Volume: 36, Issue:7

    Topics: Animals; Anticonvulsants; Cognitive Dysfunction; Depression; Disease Models, Animal; Drug Resistance

2021
CNS effects of convulsive therapy: significance for a theory of depressive psychosis.
    Proceedings of the annual meeting of the American Psychopathological Association, 1972, Volume: 60

    Topics: Alpha Rhythm; Amobarbital; Antidepressive Agents; Bipolar Disorder; Brain; Depression; Electroconvul

1972

Other Studies

42 other studies available for pentylenetetrazole and Depression

ArticleYear
DHA and EPA Prevent Seizure and Depression-Like Behavior by Inhibiting Ferroptosis and Neuroinflammation via Different Mode-of-Actions in a Pentylenetetrazole-Induced Kindling Model in Mice.
    Molecular nutrition & food research, 2022, Volume: 66, Issue:22

    Topics: Animals; Depression; Docosahexaenoic Acids; Eicosapentaenoic Acid; Ferroptosis; Mice; Neuroinflammat

2022
Exploring the ameliorative role of α7 neuronal nicotinic acetylcholine receptor modulation in epilepsy and associated comorbidities in post-PTZ-kindled mice.
    Epilepsy & behavior : E&B, 2020, Volume: 103, Issue:Pt A

    Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Anticonvulsants; Corticosterone; Depression; Dose-

2020
Glutamatergic pathway in depressive-like behavior associated with pentylenetetrazole rat model of epilepsy with history of prolonged febrile seizures.
    Life sciences, 2020, Jul-15, Volume: 253

    Topics: Amygdala; Animals; Brain-Derived Neurotrophic Factor; Depression; Epilepsy; Excitatory Amino Acid Tr

2020
Metabolic Alterations Predispose to Seizure Development in High-Fat Diet-Treated Mice: the Role of Metformin.
    Molecular neurobiology, 2020, Volume: 57, Issue:11

    Topics: Animals; Anxiety; Avoidance Learning; Behavior, Animal; Blood Glucose; Body Composition; Depression;

2020
Synthesis and Evaluation on Anticonvulsant and Antidepressant Activities of Naphthoquinone Derivatives Containing Pyrazole and Pyrimidine Fragments.
    Acta chimica Slovenica, 2020, Volume: 67, Issue:3

    Topics: Animals; Animals, Outbred Strains; Anticonvulsants; Antidepressive Agents; Depression; Male; Mice; N

2020
Creatine attenuates seizure severity, anxiety and depressive-like behaviors in pentylenetetrazole kindled mice.
    Metabolic brain disease, 2021, Volume: 36, Issue:4

    Topics: Animals; Anxiety; Convulsants; Creatine; Depression; Dose-Response Relationship, Drug; Glutathione;

2021
Rapamycin attenuates depression and anxiety-like behaviors through modulation of the NLRP3 pathway in pentylenetetrazole-kindled male Wistar rats.
    Fundamental & clinical pharmacology, 2021, Volume: 35, Issue:6

    Topics: Animals; Anxiety; Depression; Kindling, Neurologic; Male; NLR Family, Pyrin Domain-Containing 3 Prot

2021
Anticonvulsant effect of pterostilbene and its influence on the anxiety- and depression-like behavior in the pentetrazol-kindled mice: behavioral, biochemical, and molecular studies.
    Psychopharmacology, 2021, Volume: 238, Issue:11

    Topics: Animals; Anticonvulsants; Anxiety; Chromatography, Liquid; Depression; Kindling, Neurologic; Mice; P

2021
Effects of agomelatine on pentylenetetrazole-induced kindling, kindling-associated oxidative stress, and behavioral despair in mice and modulation of its actions by luzindole and 1-(m-chlorophenyl) piperazine.
    Epilepsy & behavior : E&B, 2017, Volume: 72

    Topics: Acetamides; Animals; Anticonvulsants; Antioxidants; Depression; Drug Therapy, Combination; Epilepsy;

2017
Agmatine for combined treatment of epilepsy, depression and cognitive impairment in chronic epileptic animals.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2017, Volume: 92

    Topics: Agmatine; Animals; Cognitive Dysfunction; Depression; Epilepsy; Male; Mice; Pentylenetetrazole

2017
Ferulic Acid Supplementation for Management of Depression in Epilepsy.
    Neurochemical research, 2017, Volume: 42, Issue:10

    Topics: Animals; Anticonvulsants; Brain; Coumaric Acids; Depression; Depressive Disorder; Disease Models, An

2017
Ameliorative effect of Curcumin on seizure severity, depression like behavior, learning and memory deficit in post-pentylenetetrazole-kindled mice.
    European journal of pharmacology, 2013, Mar-15, Volume: 704, Issue:1-3

    Topics: Acetylcholinesterase; Animals; Anticonvulsants; Behavior, Animal; Brain; Convulsants; Curcumin; Depr

2013
Behavioral profile of Hypericum perforatum (St. John's Wort) extract. A comparison with standard antidepressants in animal models of depression.
    European review for medical and pharmacological sciences, 2013, Volume: 17, Issue:8

    Topics: Animals; Antidepressive Agents; Depression; Disease Models, Animal; Hypericum; Male; Mice; Motor Act

2013
Ameliorative effect of Asparagus racemosus root extract against pentylenetetrazol-induced kindling and associated depression and memory deficit.
    Epilepsy & behavior : E&B, 2016, Volume: 57, Issue:Pt A

    Topics: Animals; Anticonvulsants; Asparagus Plant; Depression; Dose-Response Relationship, Drug; Epilepsy; K

2016
Protective Effect of Nerolidol Against Pentylenetetrazol-Induced Kindling, Oxidative Stress and Associated Behavioral Comorbidities in Mice.
    Neurochemical research, 2016, Volume: 41, Issue:11

    Topics: Animals; Behavior, Animal; Comorbidity; Depression; Glutathione; Kindling, Neurologic; Male; Memory

2016
Evidence in support of using a neurochemistry approach to identify therapy for both epilepsy and associated depression.
    Epilepsy & behavior : E&B, 2016, Volume: 61

    Topics: Animals; Anticonvulsants; Brain; Depression; Depressive Disorder; Disease Models, Animal; Dopamine;

2016
Anticonvulsant activity of an active fraction extracted from Crinum jagus L. (Amaryllidaceae), and its possible effects on fully kindled seizures, depression-like behaviour and oxidative stress in experimental rodent models.
    Journal of ethnopharmacology, 2016, Dec-24, Volume: 194

    Topics: Animals; Anticonvulsants; Crinum; Depression; Disease Models, Animal; Kindling, Neurologic; Male; Mi

2016
Adjuvant neuronal nitric oxide synthase inhibition for combined treatment of epilepsy and comorbid depression.
    Pharmacological reports : PR, 2017, Volume: 69, Issue:1

    Topics: Animals; Anticonvulsants; Chemotherapy, Adjuvant; Depression; Dose-Response Relationship, Drug; Enzy

2017
Adjuvant quercetin therapy for combined treatment of epilepsy and comorbid depression.
    Neurochemistry international, 2017, Volume: 104

    Topics: Animals; Anticonvulsants; Behavior, Animal; Brain; Combined Modality Therapy; Convulsants; Depressio

2017
Protective effect of spermine against pentylenetetrazole kindling epilepsy induced comorbidities in mice.
    Neuroscience research, 2017, Volume: 120

    Topics: Animals; Arginine; Avoidance Learning; Brain; Catecholamines; Comorbidity; Depression; Epilepsy; gam

2017
Re-evaluation of the effectiveness of metrazol as an analeptic agent in barbiturate depression.
    Federation proceedings, 1948, Volume: 7, Issue:1 Pt 1

    Topics: Barbital; Barbiturates; Central Nervous System Stimulants; Depression; Depressive Disorder; Pentylen

1948
On the stimulant and depressant effects of pentamethylenetetrazol in sodium diethyl barbiturate depression.
    Acta pharmacologica et toxicologica, 1946, Volume: 2, Issue:4

    Topics: Barbital; Barbiturates; Central Nervous System Stimulants; Depression; Depressive Disorder; Humans;

1946
Spadin as a new antidepressant: absence of TREK-1-related side effects.
    Neuropharmacology, 2012, Volume: 62, Issue:1

    Topics: Animals; Antidepressive Agents; Biophysical Phenomena; Blood Glucose; Brain Infarction; CD8 Antigens

2012
Regulatory role of the dopamine and norepinephrine transporters in pentylenetetrazol-kindled mice: association with effect of antidepressants.
    European journal of pharmacology, 2011, Dec-30, Volume: 673, Issue:1-3

    Topics: Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents; Atomoxetine Hydrochloride; Bupropion;

2011
Dual protective effect of Passiflora incarnata in epilepsy and associated post-ictal depression.
    Journal of ethnopharmacology, 2012, Jan-06, Volume: 139, Issue:1

    Topics: Animals; Anticonvulsants; Antidepressive Agents; Behavior, Animal; Brain; Convulsants; Depression; E

2012
Effect of saponin fraction from Ficus religiosa on memory deficit, and behavioral and biochemical impairments in pentylenetetrazol kindled mice.
    Epilepsy & behavior : E&B, 2013, Volume: 27, Issue:1

    Topics: Analysis of Variance; Animals; Avoidance Learning; Brain; Chromatography, High Pressure Liquid; Depr

2013
[Spectacular cure by cardiazol therapy of an atypical melancholia apparently incurable].
    Annales medico-psychologiques, 1953, Volume: 111, Issue:1 5

    Topics: Convulsive Therapy; Depression; Depressive Disorder; Humans; Pentylenetetrazole

1953
Studies of pentobarbital depression.
    Anesthesiology, 1954, Volume: 15, Issue:5

    Topics: Barbiturates; Depression; Depressive Disorder; Humans; Pentobarbital; Pentylenetetrazole; Poisoning;

1954
A combined psychic and somatic stimulant in the management of industrial fatigue and mild depression.
    International record of medicine, 1959, Volume: 172

    Topics: Amphetamine; Amphetamines; Central Nervous System Stimulants; Depression; Fatigue; Humans; Occupatio

1959
[On the treatment of depressive states in aged persons].
    Folia clinica internacional, 1963, Volume: 13

    Topics: Dementia; Depression; Depressive Disorder; Humans; Inositol; Pentylenetetrazole; Psychotic Disorders

1963
THE HISTOMORPHOLOGY OF EXPERIMENTAL EXCITATION.
    Neurology, 1964, Volume: 14

    Topics: Acridines; Coloring Agents; Depression; Depressive Disorder; Hippocampus; Histology; Lysergic Acid D

1964
[Observations on the therapeutic use of sub-shock doses of cardiazol].
    Deutsche medizinische Wochenschrift (1946), 1950, Aug-25, Volume: 75, Issue:33-34

    Topics: Convulsive Therapy; Depression; Depressive Disorder; Pentylenetetrazole; Shock

1950
[Recent experiences with sub-shock cardiazol therapy].
    Deutsche medizinische Wochenschrift (1946), 1950, Sep-08, Volume: 75, Issue:36

    Topics: Aged; Convulsive Therapy; Depression; Depressive Disorder; Humans; Pentylenetetrazole

1950
Re-evaluation of the effectiveness of pentamethylenetetrazol (metrazol) as an analeptic agent during thiopental depression.
    The Journal of pharmacology and experimental therapeutics, 1950, Volume: 98, Issue:3

    Topics: Central Nervous System Stimulants; Depression; Depressive Disorder; Humans; Pentylenetetrazole; Thio

1950
Reduced anxiety-- and depression-like behaviors in Emx1 homozygous mutant mice.
    Brain research, 2002, May-24, Volume: 937, Issue:1-2

    Topics: Acoustic Stimulation; Animals; Anxiety; Convulsants; Depression; Exploratory Behavior; Female; Genet

2002
Improving psychiatric drug therapy. A matter of dosage and choice.
    Geriatrics, 1974, Volume: 29, Issue:6

    Topics: Adrenal Cortex Hormones; Adult; Aged; Anticoagulants; Antidepressive Agents; Antiparkinson Agents; B

1974
Pharmacological actions of 1-(o-methoxyphenoxy)3-isopropylamino-2-propanol hydrochloride (S-D-1601), a new beta-blocking agent.
    Arzneimittel-Forschung, 1970, Volume: 20, Issue:8

    Topics: Adrenergic beta-Antagonists; Amphetamine; Anesthetics, Local; Animals; Anti-Arrhythmia Agents; Antic

1970
Answers to questions frequently asked about ECT.
    Seminars in psychiatry, 1972, Volume: 4, Issue:1

    Topics: Age Factors; Anesthesia, Intravenous; Brain Damage, Chronic; Brain Neoplasms; Depression; Electrocon

1972
Letters to the editor: Drug dosage in ECT.
    The American journal of psychiatry, 1973, Volume: 130, Issue:11

    Topics: Depression; Diazepam; Electroconvulsive Therapy; Humans; Injections, Intravenous; Methohexital; Pent

1973
Narcostimulation in depressive states.
    The American journal of psychiatry, 1968, Volume: 124, Issue:9

    Topics: Accidents; Amnesia; Anesthesia; Apnea; Central Nervous System; Convulsive Therapy; Depression; Elect

1968
Epilepsy or anesthesia with ketamine.
    Anesthesiology, 1972, Volume: 36, Issue:4

    Topics: Anesthesia; Anesthetics; Animals; Cataplexy; Cats; Central Nervous System; Cyclohexanes; Depression;

1972
On the central action of some oxoindole compounds.
    Archivum immunologiae et therapiae experimentalis, 1969, Volume: 17, Issue:1

    Topics: Absorption; Amphetamine; Animals; Blood Pressure; Central Nervous System; Depression; Drug Antagonis

1969