| Substance | Description | Relationhip Strength | Studies | Trials | Classes | Roles |
|---|
| amiodarone | [no description available] | medium | 1 | 0 | 1-benzofurans;
aromatic ketone;
organoiodine compound;
tertiary amino compound | cardiovascular drug |
| azelastine | [no description available] | medium | 1 | 0 | monochlorobenzenes;
phthalazines;
tertiary amino compound | anti-allergic agent;
anti-asthmatic drug;
bronchodilator agent;
EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor;
H1-receptor antagonist;
platelet aggregation inhibitor |
| bepridil | [no description available] | medium | 1 | 0 | pyrrolidines;
tertiary amine | anti-arrhythmia drug;
antihypertensive agent;
calcium channel blocker;
vasodilator agent |
| verapamil | [no description available] | medium | 2 | 0 | aromatic ether;
nitrile;
polyether;
tertiary amino compound | |
| clofazimine | [no description available] | medium | 1 | 0 | monochlorobenzenes;
phenazines | dye;
leprostatic drug;
non-steroidal anti-inflammatory drug |
| dipyridamole | [no description available] | medium | 1 | 0 | piperidines;
pyrimidopyrimidine;
tertiary amino compound;
tetrol | adenosine phosphodiesterase inhibitor;
EC 3.5.4.4 (adenosine deaminase) inhibitor;
platelet aggregation inhibitor;
vasodilator agent |
| ebastine | [no description available] | medium | 1 | 0 | organic molecular entity | |
| fluphenazine | [no description available] | medium | 2 | 0 | N-alkylpiperazine;
organofluorine compound;
phenothiazines | anticoronaviral agent;
dopaminergic antagonist;
phenothiazine antipsychotic drug |
| loperamide | [no description available] | medium | 2 | 0 | monocarboxylic acid amide;
monochlorobenzenes;
piperidines;
tertiary alcohol | anticoronaviral agent;
antidiarrhoeal drug;
mu-opioid receptor agonist |
| nefazodone | [no description available] | medium | 1 | 0 | aromatic ether;
monochlorobenzenes;
N-alkylpiperazine;
N-arylpiperazine;
triazoles | alpha-adrenergic antagonist;
analgesic;
antidepressant;
serotonergic antagonist;
serotonin uptake inhibitor |
| benoxinate | [no description available] | medium | 1 | 0 | amino acid ester;
benzoate ester;
substituted aniline;
tertiary amino compound | drug allergen;
local anaesthetic;
topical anaesthetic |
| oxybutynin | [no description available] | medium | 1 | 0 | acetylenic compound;
carboxylic ester;
racemate;
tertiary alcohol;
tertiary amino compound | antispasmodic drug;
calcium channel blocker;
local anaesthetic;
muscarinic antagonist;
muscle relaxant;
parasympatholytic |
| ritanserin | [no description available] | medium | 1 | 0 | organofluorine compound;
piperidines;
thiazolopyrimidine | antidepressant;
antipsychotic agent;
anxiolytic drug;
dopaminergic antagonist;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
serotonergic antagonist |
| salmeterol xinafoate | [no description available] | medium | 1 | 0 | ether;
phenols;
primary alcohol;
secondary alcohol;
secondary amino compound | |
| terfenadine | [no description available] | medium | 1 | 0 | diarylmethane | |
| thiethylperazine | [no description available] | medium | 2 | 0 | N-methylpiperazine;
phenothiazines | antiemetic;
dopaminergic antagonist;
histamine antagonist;
muscarinic antagonist;
phenothiazine antipsychotic drug;
serotonergic antagonist |
| thioridazine | [no description available] | medium | 1 | 0 | phenothiazines;
piperidines | alpha-adrenergic antagonist;
dopaminergic antagonist;
EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitor;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
first generation antipsychotic;
H1-receptor antagonist;
serotonergic antagonist |
| trimebutine | [no description available] | medium | 1 | 0 | trihydroxybenzoic acid | |
| acepromazine | [no description available] | medium | 1 | 0 | aromatic ketone;
methyl ketone;
phenothiazines;
tertiary amino compound | phenothiazine antipsychotic drug |
| emetine | [no description available] | medium | 2 | 0 | isoquinoline alkaloid;
pyridoisoquinoline | antiamoebic agent;
anticoronaviral agent;
antiinfective agent;
antimalarial;
antineoplastic agent;
antiprotozoal drug;
antiviral agent;
autophagy inhibitor;
emetic;
expectorant;
plant metabolite;
protein synthesis inhibitor |
| diltiazem | [no description available] | medium | 1 | 0 | 5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-yl acetate | antihypertensive agent;
calcium channel blocker;
vasodilator agent |
| sufentanil | [no description available] | medium | 1 | 0 | anilide;
ether;
piperidines;
thiophenes | anaesthesia adjuvant;
intravenous anaesthetic;
mu-opioid receptor agonist;
opioid analgesic |
| sertraline | [no description available] | medium | 1 | 0 | dichlorobenzene;
secondary amino compound;
tetralins | antidepressant;
serotonin uptake inhibitor |
| dironyl | [no description available] | medium | 1 | 0 | organic molecular entity | |
| chlorprothixene | [no description available] | medium | 1 | 0 | chlorprothixene | |
| thiothixene | [no description available] | medium | 2 | 0 | N-methylpiperazine | anticoronaviral agent |
| meprednisone | [no description available] | medium | 1 | 0 | 21-hydroxy steroid | |
| amodiaquine | [no description available] | medium | 1 | 0 | aminoquinoline;
organochlorine compound;
phenols;
secondary amino compound;
tertiary amino compound | anticoronaviral agent;
antimalarial;
drug allergen;
EC 2.1.1.8 (histamine N-methyltransferase) inhibitor;
non-steroidal anti-inflammatory drug;
prodrug |
| astemizole | [no description available] | medium | 1 | 0 | benzimidazoles;
piperidines | anti-allergic agent;
anticoronaviral agent;
H1-receptor antagonist |
| camostat | [no description available] | medium | 1 | 0 | benzoate ester;
carboxylic ester;
diester;
guanidines;
tertiary carboxamide | anti-inflammatory agent;
anticoronaviral agent;
antifibrinolytic drug;
antihypertensive agent;
antineoplastic agent;
antiviral agent;
serine protease inhibitor |
| carmofur | [no description available] | medium | 1 | 0 | organohalogen compound;
pyrimidines | |
| chloroquine | [no description available] | medium | 1 | 0 | aminoquinoline;
organochlorine compound;
secondary amino compound;
tertiary amino compound | anticoronaviral agent;
antimalarial;
antirheumatic drug;
autophagy inhibitor;
dermatologic drug |
| chlorpromazine | [no description available] | medium | 1 | 0 | organochlorine compound;
phenothiazines;
tertiary amine | anticoronaviral agent;
antiemetic;
dopaminergic antagonist;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
phenothiazine antipsychotic drug |
| clomipramine | [no description available] | medium | 1 | 0 | dibenzoazepine | anticoronaviral agent;
antidepressant;
EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitor;
serotonergic antagonist;
serotonergic drug;
serotonin uptake inhibitor |
| disulfiram | [no description available] | medium | 1 | 0 | organic disulfide;
organosulfur acaricide | angiogenesis inhibitor;
antineoplastic agent;
apoptosis inducer;
EC 1.2.1.3 [aldehyde dehydrogenase (NAD(+))] inhibitor;
EC 3.1.1.1 (carboxylesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
EC 5.99.1.2 (DNA topoisomerase) inhibitor;
ferroptosis inducer;
fungicide;
NF-kappaB inhibitor |
| ebselen | [no description available] | medium | 1 | 0 | benzoselenazole | anti-inflammatory drug;
antibacterial agent;
anticoronaviral agent;
antifungal agent;
antineoplastic agent;
antioxidant;
apoptosis inducer;
EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor;
EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor;
EC 1.3.1.8 [acyl-CoA dehydrogenase (NADP(+))] inhibitor;
EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitor;
EC 2.5.1.7 (UDP-N-acetylglucosamine 1-carboxyvinyltransferase) inhibitor;
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor;
EC 3.1.3.25 (inositol-phosphate phosphatase) inhibitor;
EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor;
EC 3.5.4.1 (cytosine deaminase) inhibitor;
EC 5.1.3.2 (UDP-glucose 4-epimerase) inhibitor;
enzyme mimic;
ferroptosis inhibitor;
genotoxin;
hepatoprotective agent;
neuroprotective agent;
radical scavenger |
| emodin | [no description available] | medium | 1 | 0 | trihydroxyanthraquinone | antineoplastic agent;
laxative;
plant metabolite;
tyrosine kinase inhibitor |
| fluspirilene | [no description available] | medium | 1 | 0 | diarylmethane | |
| hydroxychloroquine | [no description available] | medium | 1 | 0 | aminoquinoline;
organochlorine compound;
primary alcohol;
secondary amino compound;
tertiary amino compound | anticoronaviral agent;
antimalarial;
antirheumatic drug;
dermatologic drug |
| hydroxyzine | [no description available] | medium | 1 | 0 | hydroxyether;
monochlorobenzenes;
N-alkylpiperazine | anticoronaviral agent;
antipruritic drug;
anxiolytic drug;
dermatologic drug;
H1-receptor antagonist |
| mefloquine hydrochloride | [no description available] | medium | 1 | 0 | organofluorine compound;
piperidines;
quinolines;
secondary alcohol | |
| niclosamide | [no description available] | medium | 1 | 0 | benzamides;
C-nitro compound;
monochlorobenzenes;
salicylanilides;
secondary carboxamide | anthelminthic drug;
anticoronaviral agent;
antiparasitic agent;
apoptosis inducer;
molluscicide;
piscicide;
STAT3 inhibitor |
| promethazine | [no description available] | medium | 1 | 0 | phenothiazines;
tertiary amine | anti-allergic agent;
anticoronaviral agent;
antiemetic;
antipruritic drug;
H1-receptor antagonist;
local anaesthetic;
sedative |
| imatinib | [no description available] | medium | 1 | 0 | aromatic amine;
benzamides;
N-methylpiperazine;
pyridines;
pyrimidines | antineoplastic agent;
apoptosis inducer;
tyrosine kinase inhibitor |
| triflupromazine | [no description available] | medium | 1 | 0 | organofluorine compound;
phenothiazines;
tertiary amine | anticoronaviral agent;
antiemetic;
dopaminergic antagonist;
first generation antipsychotic |
| cycloheximide | [no description available] | medium | 1 | 0 | antibiotic fungicide;
cyclic ketone;
dicarboximide;
piperidine antibiotic;
piperidones;
secondary alcohol | anticoronaviral agent;
bacterial metabolite;
ferroptosis inhibitor;
neuroprotective agent;
protein synthesis inhibitor |
| triparanol | [no description available] | medium | 1 | 0 | stilbenoid | anticoronaviral agent |
| acetophenazine | [no description available] | medium | 1 | 0 | N-(2-hydroxyethyl)piperazine;
N-alkylpiperazine;
phenothiazines | phenothiazine antipsychotic drug |
| ribavirin | [no description available] | medium | 1 | 0 | 1-ribosyltriazole;
aromatic amide;
monocarboxylic acid amide;
primary carboxamide | anticoronaviral agent;
antiinfective agent;
antimetabolite;
antiviral agent;
EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor |
| gemcitabine | [no description available] | medium | 1 | 0 | organofluorine compound;
pyrimidine 2'-deoxyribonucleoside | antimetabolite;
antineoplastic agent;
antiviral drug;
DNA synthesis inhibitor;
EC 1.17.4.1 (ribonucleoside-diphosphate reductase) inhibitor;
environmental contaminant;
immunosuppressive agent;
photosensitizing agent;
prodrug;
radiosensitizing agent;
xenobiotic |
| methotrimeprazine | [no description available] | medium | 1 | 0 | phenothiazines;
tertiary amine | anticoronaviral agent;
cholinergic antagonist;
dopaminergic antagonist;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
non-narcotic analgesic;
phenothiazine antipsychotic drug;
serotonergic antagonist |
| lopinavir | [no description available] | medium | 1 | 0 | amphetamines;
dicarboxylic acid diamide | anticoronaviral agent;
antiviral drug;
HIV protease inhibitor |
| tanshinone ii a | [no description available] | medium | 1 | 0 | abietane diterpenoid | |
| nutlin 3 | [no description available] | medium | 1 | 0 | stilbenoid | |
| 1-methylpropyl-2-imidazolyl disulfide | [no description available] | medium | 1 | 0 | imidazoles | |
| anisomycin | [no description available] | medium | 1 | 0 | monohydroxypyrrolidine;
organonitrogen heterocyclic antibiotic | anticoronaviral agent;
antimicrobial agent;
antineoplastic agent;
antiparasitic agent;
bacterial metabolite;
DNA synthesis inhibitor;
protein synthesis inhibitor |
| homoharringtonine | [no description available] | medium | 1 | 0 | alkaloid ester;
enol ether;
organic heteropentacyclic compound;
tertiary alcohol | anticoronaviral agent;
antineoplastic agent;
apoptosis inducer;
protein synthesis inhibitor |
| terconazole | [no description available] | medium | 1 | 0 | 1-(4-{[2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)-4-isopropylpiperazine | |
| 1-(2-Naphthylmethyl)-2,3-dioxo-indoline-5-carboxamide | [no description available] | medium | 1 | 0 | indolecarboxamide | anticoronaviral agent |
| hirsutanone | [no description available] | medium | 1 | 0 | diarylheptanoid | |
| benztropine | [no description available] | medium | 1 | 0 | diarylmethane | |
| tamoxifen | [no description available] | medium | 2 | 0 | stilbenoid;
tertiary amino compound | angiogenesis inhibitor;
antineoplastic agent;
bone density conservation agent;
EC 1.2.3.1 (aldehyde oxidase) inhibitor;
EC 2.7.11.13 (protein kinase C) inhibitor;
estrogen antagonist;
estrogen receptor antagonist;
estrogen receptor modulator |
| S-[5-(trifluoromethyl)-4H-1,2,4-triazol-3-yl] 5-(phenylethynyl)furan-2-carbothioate | [no description available] | medium | 1 | 0 | acetylenic compound;
furans;
organofluorine compound;
thioester;
triazoles | |
| toremifene | [no description available] | medium | 1 | 0 | aromatic ether;
organochlorine compound;
tertiary amine | antineoplastic agent;
bone density conservation agent;
estrogen antagonist;
estrogen receptor modulator |
| dasatinib | [no description available] | medium | 1 | 0 | 1,3-thiazoles;
aminopyrimidine;
monocarboxylic acid amide;
N-(2-hydroxyethyl)piperazine;
N-arylpiperazine;
organochlorine compound;
secondary amino compound;
tertiary amino compound | anticoronaviral agent;
antineoplastic agent;
tyrosine kinase inhibitor |
| N-(4-Butan-2-ylphenyl)-N-[2-(cyclopentylamino)-2-oxo-1-pyridin-3-ylethyl]furan-2-carboxamide | [no description available] | medium | 1 | 0 | aromatic amide;
furans | anticoronaviral agent |
| quercetin | [no description available] | medium | 1 | 0 | 7-hydroxyflavonol;
pentahydroxyflavone | antibacterial agent;
antineoplastic agent;
antioxidant;
Aurora kinase inhibitor;
chelator;
EC 1.10.99.2 [ribosyldihydronicotinamide dehydrogenase (quinone)] inhibitor;
geroprotector;
phytoestrogen;
plant metabolite;
protein kinase inhibitor;
radical scavenger |
| luteolin | [no description available] | medium | 1 | 0 | 3'-hydroxyflavonoid;
tetrahydroxyflavone | angiogenesis inhibitor;
anti-inflammatory agent;
antineoplastic agent;
apoptosis inducer;
c-Jun N-terminal kinase inhibitor;
EC 2.3.1.85 (fatty acid synthase) inhibitor;
immunomodulator;
nephroprotective agent;
plant metabolite;
radical scavenger;
vascular endothelial growth factor receptor antagonist |
| amentoflavone | [no description available] | medium | 1 | 0 | biflavonoid;
hydroxyflavone;
ring assembly | angiogenesis inhibitor;
antiviral agent;
cathepsin B inhibitor;
P450 inhibitor;
plant metabolite |
| savinin | [no description available] | medium | 1 | 0 | benzodioxoles;
gamma-lactone;
lignan | anti-inflammatory agent;
anticoronaviral agent;
EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor;
plant metabolite;
T-cell proliferation inhibitor |
| dothiepin hydrochloride | [no description available] | medium | 1 | 0 | dothiepin | |
| broussochalcone a | [no description available] | medium | 1 | 0 | | |
| rupintrivir | [no description available] | medium | 1 | 0 | | |
| 5-Chloro-3-pyridinyl 2-furoate | [no description available] | medium | 1 | 0 | carboxylic ester | anticoronaviral agent |
| sotrastaurin | [no description available] | medium | 1 | 0 | indoles;
maleimides;
N-alkylpiperazine;
N-arylpiperazine;
quinazolines | anticoronaviral agent;
EC 2.7.11.13 (protein kinase C) inhibitor;
immunosuppressive agent |
| saracatinib | [no description available] | medium | 1 | 0 | aromatic ether;
benzodioxoles;
diether;
N-methylpiperazine;
organochlorine compound;
oxanes;
quinazolines;
secondary amino compound | anticoronaviral agent;
antineoplastic agent;
apoptosis inducer;
autophagy inducer;
EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor;
radiosensitizing agent |
| np 031112 | [no description available] | medium | 1 | 0 | benzenes;
naphthalenes;
thiadiazolidine | anti-inflammatory agent;
apoptosis inducer;
EC 2.7.11.26 (tau-protein kinase) inhibitor;
neuroprotective agent |
| Benzotriazol-1-yl 1H-indole-5-carboxylate | [no description available] | medium | 1 | 0 | indolyl carboxylic acid | anticoronaviral agent |
| 5-Chloropyridin-3-yl 5-(4-chlorophenyl)furan-2-carboxylate | [no description available] | medium | 1 | 0 | carboxylic ester | anticoronaviral agent |
| (5-Chloropyridin-3-yl) 1H-indole-5-carboxylate | [no description available] | medium | 1 | 0 | indolyl carboxylic acid | anticoronaviral agent |
| 5-Chloropyridin-3-yl 1H-indole-2-carboxylate | [no description available] | medium | 1 | 0 | indolyl carboxylic acid | anticoronaviral agent |
| GRL-0617 | [no description available] | medium | 1 | 0 | benzamides;
naphthalenes;
secondary carboxamide;
substituted aniline | anticoronaviral agent;
protease inhibitor |
| (5-Chloropyridin-3-yl) 1H-indole-4-carboxylate | [no description available] | medium | 1 | 0 | indolyl carboxylic acid | anticoronaviral agent |
| KOM70144 | [no description available] | medium | 1 | 0 | acetamides;
benzamides;
naphthalenes;
secondary carboxamide | anticoronaviral agent;
protease inhibitor |
| N-[(1R)-2-(tert-butylamino)-2-oxo-1-(3-pyridinyl)ethyl]-N-(4-tert-butylphenyl)-2-furancarboxamide | [no description available] | medium | 1 | 0 | aromatic amide;
furans | |
| s 8932 | [no description available] | medium | 1 | 0 | aromatic amine;
C-nucleoside;
carboxylic ester;
nitrile;
phosphoramidate ester;
pyrrolotriazine | anticoronaviral agent;
antiviral drug;
prodrug |
| N-[(2S)-3-cyclohexyl-1-oxo-1-({(2S)-1-oxo-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}amino)propan-2-yl]-1H-indole-2-carboxamide | [no description available] | medium | 1 | 0 | aldehyde;
indolecarboxamide;
oligopeptide;
pyrrolidin-2-ones;
secondary carboxamide | anticoronaviral agent;
EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor |
| molnupiravir | [no description available] | medium | 1 | 0 | isopropyl ester;
ketoxime;
nucleoside analogue | anticoronaviral agent;
antiviral drug;
prodrug |
| 3-fluoro-Nalpha-(1H-indol-2-ylcarbonyl)-N-{(2S)-1-oxo-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-L-phenylalaninamide | [no description available] | medium | 1 | 0 | aldehyde;
indolecarboxamide;
monofluorobenzenes;
oligopeptide;
pyrrolidin-2-ones;
secondary carboxamide | anticoronaviral agent;
EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor |
| pheniramine | [no description available] | medium | 1 | 0 | pyridines;
tertiary amino compound | |
| diphenhydramine | [no description available] | medium | 10 | 0 | ether;
tertiary amino compound | anti-allergic agent;
antidyskinesia agent;
antiemetic;
antiparkinson drug;
antipruritic drug;
antitussive;
H1-receptor antagonist;
local anaesthetic;
muscarinic antagonist;
oneirogen;
sedative |
| phenothiazine | [no description available] | medium | 1 | 0 | phenothiazine | ferroptosis inhibitor;
plant metabolite;
radical scavenger |
| perphenazine | [no description available] | medium | 1 | 0 | N-(2-hydroxyethyl)piperazine;
N-alkylpiperazine;
organochlorine compound;
phenothiazines | antiemetic;
dopaminergic antagonist;
phenothiazine antipsychotic drug |
| caffeine | [no description available] | medium | 3 | 0 | purine alkaloid;
trimethylxanthine | adenosine A2A receptor antagonist;
adenosine receptor antagonist;
adjuvant;
central nervous system stimulant;
diuretic;
EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor;
EC 3.1.4.* (phosphoric diester hydrolase) inhibitor;
environmental contaminant;
food additive;
fungal metabolite;
geroprotector;
human blood serum metabolite;
mouse metabolite;
mutagen;
plant metabolite;
psychotropic drug;
ryanodine receptor agonist;
xenobiotic |
| 8-chlorotheophylline | [no description available] | medium | 1 | 0 | organochlorine compound;
purines | central nervous system stimulant |
| theophylline | [no description available] | medium | 2 | 1 | dimethylxanthine | adenosine receptor antagonist;
anti-asthmatic drug;
anti-inflammatory agent;
bronchodilator agent;
drug metabolite;
EC 3.1.4.* (phosphoric diester hydrolase) inhibitor;
fungal metabolite;
human blood serum metabolite;
immunomodulator;
muscle relaxant;
vasodilator agent |
| alizarin red s | [no description available] | medium | 1 | 0 | organic sodium salt;
organosulfonate salt | histological dye |
| clemastine | [no description available] | medium | 1 | 0 | monochlorobenzenes;
N-alkylpyrrolidine | anti-allergic agent;
antipruritic drug;
H1-receptor antagonist;
muscarinic antagonist |
| hycanthone | [no description available] | medium | 2 | 0 | thioxanthenes | mutagen;
schistosomicide drug |
| rhodamine 123 | [no description available] | medium | 1 | 0 | organic cation;
xanthene dye | fluorochrome |
| bamipine | [no description available] | medium | 1 | 0 | aromatic amine | |
| piperidines | [no description available] | medium | 1 | 0 | | |
| trifluoperazine | [no description available] | medium | 1 | 0 | N-alkylpiperazine;
N-methylpiperazine;
organofluorine compound;
phenothiazines | antiemetic;
calmodulin antagonist;
dopaminergic antagonist;
EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitor;
EC 5.3.3.5 (cholestenol Delta-isomerase) inhibitor;
phenothiazine antipsychotic drug |
| quinine | [no description available] | medium | 1 | 0 | cinchona alkaloid | antimalarial;
muscle relaxant;
non-narcotic analgesic |
| quinidine | [no description available] | medium | 1 | 0 | cinchona alkaloid | alpha-adrenergic antagonist;
anti-arrhythmia drug;
antimalarial;
drug allergen;
EC 1.14.13.181 (13-deoxydaunorubicin hydroxylase) inhibitor;
EC 3.6.3.44 (xenobiotic-transporting ATPase) inhibitor;
muscarinic antagonist;
P450 inhibitor;
potassium channel blocker;
sodium channel blocker |
| selegiline | [no description available] | medium | 1 | 1 | selegiline;
terminal acetylenic compound | geroprotector |
| fenethylline | [no description available] | medium | 1 | 1 | oxopurine | |
| miltefosine | [no description available] | low | 0 | 0 | phosphocholines;
phospholipid | anti-inflammatory agent;
anticoronaviral agent;
antifungal agent;
antineoplastic agent;
antiprotozoal drug;
apoptosis inducer;
immunomodulator;
protein kinase inhibitor |
| ethylmaleimide | [no description available] | low | 0 | 0 | maleimides | anticoronaviral agent;
EC 1.3.1.8 [acyl-CoA dehydrogenase (NADP(+))] inhibitor;
EC 2.1.1.122 [(S)-tetrahydroprotoberberine N-methyltransferase] inhibitor;
EC 2.7.1.1 (hexokinase) inhibitor |
| phenazopyridine | [no description available] | low | 0 | 0 | diaminopyridine;
monoazo compound | anticoronaviral agent;
carcinogenic agent;
local anaesthetic;
non-narcotic analgesic |
| promethazine hydrochloride | [no description available] | low | 0 | 0 | hydrochloride | anti-allergic agent;
anticoronaviral agent;
antiemetic;
antipruritic drug;
geroprotector;
H1-receptor antagonist;
local anaesthetic;
sedative |
| chlorpromazine hydrochloride | [no description available] | low | 0 | 0 | hydrochloride;
phenothiazines | anticoronaviral agent;
phenothiazine antipsychotic drug |
| 5-bromoisatin | [no description available] | low | 0 | 0 | indoles | anticoronaviral agent |
| 5-Methoxyisatin | [no description available] | low | 0 | 0 | indoles | anticoronaviral agent |
| brequinar | [no description available] | low | 0 | 0 | biphenyls;
monocarboxylic acid;
monofluorobenzenes;
quinolinemonocarboxylic acid | anticoronaviral agent;
antimetabolite;
antineoplastic agent;
antiviral agent;
EC 1.3.5.2 [dihydroorotate dehydrogenase (quinone)] inhibitor;
immunosuppressive agent;
pyrimidine synthesis inhibitor |
| gemcitabine hydrochloride | [no description available] | low | 0 | 0 | hydrochloride;
organofluorine compound | anticoronaviral agent;
antimetabolite;
antineoplastic agent;
antiviral drug;
EC 1.17.4.1 (ribonucleoside-diphosphate reductase) inhibitor;
immunosuppressive agent;
radiosensitizing agent |
| amodiaquine hydrochloride | [no description available] | low | 0 | 0 | hydrochloride | anticoronaviral agent |
| baicalin | [no description available] | low | 0 | 0 | dihydroxyflavone;
glucosiduronic acid;
glycosyloxyflavone;
monosaccharide derivative | antiatherosclerotic agent;
antibacterial agent;
anticoronaviral agent;
antineoplastic agent;
antioxidant;
cardioprotective agent;
EC 2.7.7.48 (RNA-directed RNA polymerase) inhibitor;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
ferroptosis inhibitor;
neuroprotective agent;
non-steroidal anti-inflammatory drug;
plant metabolite;
prodrug |
| aloxistatin | [no description available] | low | 0 | 0 | epoxide;
ethyl ester;
L-leucine derivative;
monocarboxylic acid amide | anticoronaviral agent;
cathepsin B inhibitor |
| siquil | [no description available] | low | 0 | 0 | hydrochloride | anticoronaviral agent |
| fluphenazine hydrochloride | [no description available] | low | 0 | 0 | phenothiazines | anticoronaviral agent |
| clomipramine hydrochloride | [no description available] | low | 0 | 0 | hydrochloride | anticoronaviral agent;
antidepressant;
serotonergic antagonist;
serotonergic drug |
| loperamide hydrochloride | [no description available] | low | 0 | 0 | hydrochloride | anticoronaviral agent;
antidiarrhoeal drug;
mu-opioid receptor agonist |
| lycorine | [no description available] | low | 0 | 0 | indolizidine alkaloid | anticoronaviral agent;
antimalarial;
plant metabolite;
protein synthesis inhibitor |
| 5-Chloro-1H-indole-2,3-dione | [no description available] | low | 0 | 0 | indoles | anticoronaviral agent |
| 5-iodoisatin | [no description available] | low | 0 | 0 | indoles | anticoronaviral agent |
| mizoribine | [no description available] | low | 0 | 0 | imidazoles | anticoronaviral agent |
| tanshinone | [no description available] | low | 0 | 0 | abietane diterpenoid | anticoronaviral agent |
| betulonic acid | [no description available] | low | 0 | 0 | triterpenoid | anticoronaviral agent |
| imatinib mesylate | [no description available] | low | 0 | 0 | methanesulfonate salt | anticoronaviral agent;
antineoplastic agent;
apoptosis inducer;
tyrosine kinase inhibitor |
| cryptotanshinone | [no description available] | low | 0 | 0 | abietane diterpenoid | anticoronaviral agent |
| anacardic acid | [no description available] | low | 0 | 0 | hydroxy monocarboxylic acid;
hydroxybenzoic acid | anti-inflammatory agent;
antibacterial agent;
anticoronaviral agent;
apoptosis inducer;
EC 2.3.1.48 (histone acetyltransferase) inhibitor;
EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor;
neuroprotective agent;
plant metabolite |
| n(4)-hydroxycytidine | [no description available] | low | 0 | 0 | ketoxime;
nucleoside analogue | anticoronaviral agent;
antiviral agent;
drug metabolite;
human xenobiotic metabolite |
| sorafenib | [no description available] | low | 0 | 0 | (trifluoromethyl)benzenes;
aromatic ether;
monochlorobenzenes;
phenylureas;
pyridinecarboxamide | angiogenesis inhibitor;
anticoronaviral agent;
antineoplastic agent;
EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor;
ferroptosis inducer;
tyrosine kinase inhibitor |
| 5-Fluoroisatin | [no description available] | low | 0 | 0 | indoles | anticoronaviral agent |
| wortmannin | [no description available] | low | 0 | 0 | acetate ester;
cyclic ketone;
delta-lactone;
organic heteropentacyclic compound | anticoronaviral agent;
antineoplastic agent;
autophagy inhibitor;
EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor;
geroprotector;
Penicillium metabolite;
radiosensitizing agent |
| theasinensin a | [no description available] | low | 0 | 0 | biflavonoid;
gallate ester;
proanthocyanidin | anti-inflammatory agent;
anticoronaviral agent;
apoptosis inducer;
EC 3.2.1.20 (alpha-glucosidase) inhibitor;
hepatoprotective agent;
hypoglycemic agent;
melanin synthesis inhibitor;
plant metabolite |
| mycophenolic acid | [no description available] | low | 0 | 0 | 2-benzofurans;
gamma-lactone;
monocarboxylic acid;
phenols | anticoronaviral agent;
antimicrobial agent;
antineoplastic agent;
EC 1.1.1.205 (IMP dehydrogenase) inhibitor;
environmental contaminant;
immunosuppressive agent;
mycotoxin;
Penicillium metabolite;
xenobiotic |
| favipiravir | [no description available] | low | 0 | 0 | hydroxypyrazine;
organofluorine compound;
primary carboxamide | anticoronaviral agent;
antiviral drug;
EC 2.7.7.48 (RNA-directed RNA polymerase) inhibitor |
| likviriton | [no description available] | low | 0 | 0 | beta-D-glucoside;
flavanone glycoside;
monohydroxyflavanone;
monosaccharide derivative | anti-inflammatory agent;
anticoronaviral agent;
plant metabolite |
| s 1033 | [no description available] | low | 0 | 0 | (trifluoromethyl)benzenes;
imidazoles;
pyridines;
pyrimidines;
secondary amino compound;
secondary carboxamide | anticoronaviral agent;
antineoplastic agent;
tyrosine kinase inhibitor |
| mercaptopurine | [no description available] | low | 0 | 0 | aryl thiol;
purines;
thiocarbonyl compound | anticoronaviral agent;
antimetabolite;
antineoplastic agent |
| (4-Methyl-2-oxochromen-7-yl) furan-2-carboxylate | [no description available] | low | 0 | 0 | coumarins | anticoronaviral agent |
| 2-(Benzotriazol-1-yl)-1-(4-bromophenyl)ethanone | [no description available] | low | 0 | 0 | aromatic ketone | anticoronaviral agent |
| (4-Ethyl-2-oxochromen-7-yl) furan-2-carboxylate | [no description available] | low | 0 | 0 | coumarins | anticoronaviral agent |
| (4-Methoxyphenyl)-(2-methylsulfanyl-6,7-dihydro-[1,4]dioxino[2,3-f]benzimidazol-3-yl)methanone | [no description available] | low | 0 | 0 | benzodioxine | anticoronaviral agent |
| 1-(N-[2-(Benzotriazol-1-yl)acetyl]-4-methoxyanilino)-N-cyclopentylcyclohexane-1-carboxamide | [no description available] | low | 0 | 0 | organonitrogen compound;
organooxygen compound | anticoronaviral agent |
| (E)-4-Phenyl-2-(3-(thiophen-2-yl)acrylamido)thiophene-3-carboxylic acid | [no description available] | low | 0 | 0 | thiophenecarboxylic acid | anticoronaviral agent |
| CID 2131972 | [no description available] | low | 0 | 0 | N-acylglycine | anticoronaviral agent |
| 4-[4-(2,3,5,6-Tetramethylphenyl)sulfonylpiperazine-1-carbonyl]-1H-quinolin-2-one | [no description available] | low | 0 | 0 | quinolines | anticoronaviral agent |
| 4-[4-(2,3-Dimethylphenyl)piperazine-1-carbonyl]-1H-quinolin-2-one | [no description available] | low | 0 | 0 | quinolines | anticoronaviral agent |
| 4-[4-[3-(Trifluoromethyl)phenyl]piperazine-1-carbonyl]-1H-quinolin-2-one | [no description available] | low | 0 | 0 | quinolines | anticoronaviral agent |
| 1-Benzyl-3-pyridin-3-yl-1H-pyrazole-4-carbaldehyde | [no description available] | low | 0 | 0 | pyrazolopyridine | anticoronaviral agent |
| 2-Chloro-1-[2,5-dimethyl-1-(3-nitrophenyl)-1H-pyrrol-3-yl]ethan-1-one | [no description available] | low | 0 | 0 | pyrroles | anticoronaviral agent |
| N-[2-(2-Methoxyphenoxy)ethyl]-2-oxo-1H-quinoline-4-carboxamide | [no description available] | low | 0 | 0 | quinolines | anticoronaviral agent |
| thioguanine anhydrous | [no description available] | low | 0 | 0 | 2-aminopurines | anticoronaviral agent;
antimetabolite;
antineoplastic agent |
| tamoxifen citrate | [no description available] | low | 0 | 0 | citrate salt | angiogenesis inhibitor;
anticoronaviral agent |
| 6-methoxy-3-nitro-2-(phenylsulfonyl)pyridine | [no description available] | low | 0 | 0 | sulfonic acid derivative | anticoronaviral agent |
| 5-(4-Chloro-benzenesulfonyl)-pyrimidine-2,4-diamine | [no description available] | low | 0 | 0 | sulfonic acid derivative | anticoronaviral agent |
| 4-Chloro-2-(5-methyl-1,3-dioxooctahydro-2H-isoindol-2-yl)phenyl 2-furoate | [no description available] | low | 0 | 0 | pyrrolidines | anticoronaviral agent |
| toremifene citrate | [no description available] | low | 0 | 0 | stilbenoid | anticoronaviral agent |
| emetine dihydrochloride | [no description available] | low | 0 | 0 | hydrochloride | anticoronaviral agent;
antimalarial;
antineoplastic agent;
antiprotozoal drug;
antiviral agent;
autophagy inhibitor;
emetic;
protein synthesis inhibitor |
| CID 3191469 | [no description available] | low | 0 | 0 | acetamides;
anilide | anticoronaviral agent |
| CID 3192987 | [no description available] | low | 0 | 0 | N-arylpiperazine | anticoronaviral agent |
| N-[2-(Cyclopentylamino)-2-oxo-1-pyridin-3-ylethyl]-N-(4-propan-2-ylphenyl)furan-2-carboxamide | [no description available] | low | 0 | 0 | aromatic amide;
furans | anticoronaviral agent |
| 2-(N-[2-(Benzotriazol-1-yl)acetyl]-2,4,6-trimethylanilino)-N-tert-butyl-2-thiophen-3-ylacetamide | [no description available] | low | 0 | 0 | organonitrogen compound;
organooxygen compound | anticoronaviral agent |
| CID 3198732 | [no description available] | low | 0 | 0 | acetamides;
anilide | anticoronaviral agent |
| CID 3206295 | [no description available] | low | 0 | 0 | organonitrogen compound;
organooxygen compound | anticoronaviral agent |
| 1-(Chloroacetyl)-3-(1H-indol-3-yl)-5-(4-methoxyphenyl)-4,5-dihydro-1H-pyrazol-4-ol | [no description available] | low | 0 | 0 | indoles | anticoronaviral agent |
| 8-(Trifluoromethyl)-9H-purin-6-amine | [no description available] | low | 0 | 0 | 6-aminopurines | anticoronaviral agent |
| 2-Chloro-1-[5-(3,4-dimethoxyphenyl)-3-(thiophen-2-yl)-4,5-dihydro-1H-pyrazol-1-yl]ethan-1-one | [no description available] | low | 0 | 0 | dimethoxybenzene | anticoronaviral agent |
| 1-(Chloroacetyl)-5-[4-(difluoromethoxy)-3-methoxyphenyl]-3-thien-2-yl-4,5-dihydro-1H-pyrazole | [no description available] | low | 0 | 0 | methoxybenzenes | anticoronaviral agent |
| 2-Chloro-1-[3-(4-methylphenyl)-5-thiophen-2-yl-3,4-dihydropyrazol-2-yl]ethanone | [no description available] | low | 0 | 0 | toluenes | anticoronaviral agent |
| 5-Nitroisatin | [no description available] | low | 0 | 0 | indoles | anticoronaviral agent |
| N-Cyclopentyl-2-(N-methyl3-chlorobenzenesulfonamido)acetamide | [no description available] | low | 0 | 0 | sulfonamide | anticoronaviral agent |
| 2-(Chloroacetyl)-N,2-diphenylhydrazinecarboxamide | [no description available] | low | 0 | 0 | ureas | anticoronaviral agent |
| N-(4-Nitro-1,2,5-oxadiazol-3-yl)-2-pyridin-2-ylsulfanylacetamide | [no description available] | low | 0 | 0 | aromatic amide | anticoronaviral agent |
| 2-Chloro-1-[5-(furan-2-yl)-3-(5-methylfuran-2-yl)-4,5-dihydro-1H-pyrazol-1-yl]ethan-1-one | [no description available] | low | 0 | 0 | pyrazolidines | anticoronaviral agent |
| mycophenolate mofetil | [no description available] | low | 0 | 0 | carboxylic ester;
ether;
gamma-lactone;
phenols;
tertiary amino compound | anticoronaviral agent;
EC 1.1.1.205 (IMP dehydrogenase) inhibitor;
immunosuppressive agent;
prodrug |
| baicalein | [no description available] | low | 0 | 0 | trihydroxyflavone | angiogenesis inhibitor;
anti-inflammatory agent;
antibacterial agent;
anticoronaviral agent;
antifungal agent;
antineoplastic agent;
antioxidant;
apoptosis inducer;
EC 1.13.11.31 (arachidonate 12-lipoxygenase) inhibitor;
EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor;
EC 4.1.1.17 (ornithine decarboxylase) inhibitor;
ferroptosis inhibitor;
geroprotector;
hormone antagonist;
plant metabolite;
prostaglandin antagonist;
radical scavenger |
| camostat mesylate | [no description available] | low | 0 | 0 | methanesulfonate salt | anti-inflammatory agent;
anticoronaviral agent;
antifibrinolytic drug;
antihypertensive agent;
antineoplastic agent;
antiviral agent;
serine protease inhibitor |
| cyclosporine | [no description available] | low | 0 | 0 | homodetic cyclic peptide | anti-asthmatic drug;
anticoronaviral agent;
antifungal agent;
antirheumatic drug;
carcinogenic agent;
dermatologic drug;
EC 3.1.3.16 (phosphoprotein phosphatase) inhibitor;
geroprotector;
immunosuppressive agent;
metabolite |
| sirolimus | [no description available] | low | 0 | 0 | antibiotic antifungal drug;
cyclic acetal;
cyclic ketone;
ether;
macrolide lactam;
organic heterotricyclic compound;
secondary alcohol | antibacterial drug;
anticoronaviral agent;
antineoplastic agent;
bacterial metabolite;
geroprotector;
immunosuppressive agent;
mTOR inhibitor |
| cinanserin | [no description available] | low | 0 | 0 | aryl sulfide;
cinnamamides;
secondary carboxamide;
tertiary amino compound | anticoronaviral agent;
antiviral agent;
EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor |
| 2-(1H-1,2,3-Benzotriazol-1-yl)-N'-(3,4,5-trimethoxybenzylidene)acetohydrazide | [no description available] | low | 0 | 0 | benzotriazoles | anticoronaviral agent |
| N-[(5-methyl-1,2-oxazol-3-yl)carbonyl]-L-alanyl-L-valyl-N-{(2S,3E)-5-(benzyloxy)-5-oxo-1-[(3S)-2-oxopyrrolidin-3-yl]pent-3-en-2-yl}-L-leucinamide | [no description available] | low | 0 | 0 | benzyl ester;
isoxazoles;
pyrrolidin-2-ones;
tripeptide | anticoronaviral agent;
antiviral agent;
EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor |
| everolimus | [no description available] | low | 0 | 0 | cyclic acetal;
cyclic ketone;
ether;
macrolide lactam;
primary alcohol;
secondary alcohol | anticoronaviral agent;
antineoplastic agent;
geroprotector;
immunosuppressive agent;
mTOR inhibitor |
| Ethyl (E,4S)-4-[[(2S)-2-[[(2S)-3-methyl-2-(phenylmethoxycarbonylamino)butanoyl]amino]-3-phenylpropanoyl]amino]-5-[(3S)-2-oxopyrrolidin-3-yl]pent-2-enoate | [no description available] | low | 0 | 0 | dipeptide | anticoronaviral agent |
| plitidepsin | [no description available] | low | 0 | 0 | didemnin | anticoronaviral agent;
antineoplastic agent;
marine metabolite |
| azd 6244 | [no description available] | low | 0 | 0 | benzimidazoles;
bromobenzenes;
hydroxamic acid ester;
monochlorobenzenes;
organofluorine compound;
secondary amino compound | anticoronaviral agent;
antineoplastic agent;
EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor |
| PB28 | [no description available] | low | 0 | 0 | aromatic ether;
piperazines;
tetralins | anticoronaviral agent;
antineoplastic agent;
apoptosis inducer;
sigma-2 receptor agonist |
| Dihydrotanshinone I | [no description available] | low | 0 | 0 | abietane diterpenoid | anticoronaviral agent |
| alisporivir | [no description available] | low | 0 | 0 | homodetic cyclic peptide | anticoronaviral agent |
| PF-00835231 | [no description available] | low | 0 | 0 | aromatic ether;
indolecarboxamide;
L-leucine derivative;
primary alcohol;
pyrrolidin-2-ones;
secondary carboxamide | anticoronaviral agent;
drug metabolite;
EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor |
| trametinib | [no description available] | low | 0 | 0 | acetamides;
aromatic amine;
cyclopropanes;
organofluorine compound;
organoiodine compound;
pyridopyrimidine;
ring assembly | anticoronaviral agent;
antineoplastic agent;
EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor;
geroprotector |
| narlaprevir | [no description available] | low | 0 | 0 | azabicyclohexane;
cyclopropanes;
pyrrolidinecarboxamide;
secondary carboxamide;
sulfone;
tertiary carboxamide;
ureas | anticoronaviral agent;
antiviral drug;
EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor;
hepatitis C protease inhibitor |
| 5-Bromopyridin-3-yl furan-2-carboxylate | [no description available] | low | 0 | 0 | carboxylic ester | anticoronaviral agent |
| nutlin-3b | [no description available] | low | 0 | 0 | Nutlin;
piperazinone | anticoronaviral agent |
| 1-(2,3-Dihydro-1,4-benzodioxin-3-ylmethyl)-5-methoxy-isatin | [no description available] | low | 0 | 0 | benzodioxine | anticoronaviral agent |
| 1-(2,3-Dihydro-1,4-benzodioxin-3-ylmethyl)-5-ethoxy-isatin | [no description available] | low | 0 | 0 | benzodioxine | anticoronaviral agent |
| brequinar sodium | [no description available] | low | 0 | 0 | organic sodium salt | anticoronaviral agent;
antimetabolite;
antineoplastic agent;
antiviral agent;
EC 1.3.5.2 [dihydroorotate dehydrogenase (quinone)] inhibitor;
immunosuppressive agent;
pyrimidine synthesis inhibitor |
| N-[5-Ethyl-1-(2-morpholin-4-ylethyl)-2-oxo-3H-indol-3-yl]acetamide;hydron;chloride | [no description available] | low | 0 | 0 | N-acyl-amino acid | anticoronaviral agent |
| N-[5-Bromo-1-(2-morpholin-4-ylethyl)-2-oxo-3H-indol-3-yl]acetamide;hydron;chloride | [no description available] | low | 0 | 0 | N-acyl-amino acid | anticoronaviral agent |
| N-[5-Fluoro-1-(2-morpholin-4-ylethyl)-2-oxo-3H-indol-3-yl]acetamide;hydron;chloride | [no description available] | low | 0 | 0 | N-acyl-amino acid | anticoronaviral agent |
| 2-(3-Amino-3-oxopropyl)-3-(4-methylbenzoyl)-2H-indazole 1-oxide | [no description available] | low | 0 | 0 | benzoylpyrazole | anticoronaviral agent |
| 3-(4-Amino-3,5-dichlorobenzoyl)-2-(3-amino-3-oxopropyl)-2H-indazole 1-oxide | [no description available] | low | 0 | 0 | benzoylpyrazole | anticoronaviral agent |
| 2-(3-Amino-3-oxopropyl)-3-(4-chlorobenzoyl)-2H-indazole 1-oxide | [no description available] | low | 0 | 0 | benzoylpyrazole | anticoronaviral agent |
| gsk 2126458 | [no description available] | low | 0 | 0 | aromatic ether;
difluorobenzene;
pyridazines;
pyridines;
quinolines;
sulfonamide | anticoronaviral agent;
antineoplastic agent;
autophagy inducer;
EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor;
mTOR inhibitor;
radiosensitizing agent |
| dabrafenib | [no description available] | low | 0 | 0 | 1,3-thiazoles;
aminopyrimidine;
organofluorine compound;
sulfonamide | anticoronaviral agent;
antineoplastic agent;
B-Raf inhibitor |
| GS-441524 | [no description available] | low | 0 | 0 | aromatic amine;
C-nucleoside;
nitrile;
pyrrolotriazine | anticoronaviral agent;
antiviral agent;
drug metabolite |
| Benzyl N-[(2S)-3-methyl-1-[[(2S)-4-methyl-1-oxo-1-[[(2S)-1-oxo-3-[(3S)-2-oxopyrrolidin-3-yl]-1-(1,3-thiazol-2-yl)propan-2-yl]amino]pentan-2-yl]amino]-1-oxobutan-2-yl]carbamate | [no description available] | low | 0 | 0 | dipeptide | anticoronaviral agent |
| pyrvinium pamoate | [no description available] | low | 0 | 0 | naphthoic acid | anticoronaviral agent |
| GS-443902 | [no description available] | low | 0 | 0 | aromatic amine;
C-nucleoside;
nitrile;
organic triphosphate;
pyrrolotriazine | anticoronaviral agent;
antiviral drug;
drug metabolite |
| PF-07304814 | [no description available] | low | 0 | 0 | aromatic ether;
indolecarboxamide;
L-leucine derivative;
phosphate monoester;
pyrrolidin-2-ones;
secondary carboxamide | anticoronaviral agent;
EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor;
prodrug |
| nirmatrelvir | [no description available] | low | 0 | 0 | azabicyclohexane;
nitrile;
organofluorine compound;
pyrrolidin-2-ones;
pyrrolidinecarboxamide;
secondary carboxamide;
tertiary carboxamide | anticoronaviral agent;
EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor |
| b 844-39 | [no description available] | low | 0 | 0 | diarylmethane | |
| 3-[(4-chlorophenyl)-phenylmethoxy]-8-methyl-8-azabicyclo[3.2.1]octane | [no description available] | low | 0 | 0 | diarylmethane | |
| adiphenine | [no description available] | low | 0 | 0 | diarylmethane | |
| 3-(2'-aminobenzhydryloxy)tropane | [no description available] | low | 0 | 0 | diarylmethane | |
| 2,2-bis(4-glycidyloxyphenyl)propane | [no description available] | low | 0 | 0 | diarylmethane | |
| benproperine | [no description available] | low | 0 | 0 | diarylmethane | |
| cogentin | [no description available] | low | 0 | 0 | diarylmethane | |
| bifemelane | [no description available] | low | 0 | 0 | diarylmethane | |
| bisacodyl | [no description available] | low | 0 | 0 | diarylmethane | |
| chlorcyclizine | [no description available] | low | 0 | 0 | diarylmethane | |
| cifenline | [no description available] | low | 0 | 0 | diarylmethane | |
| clidinium | [no description available] | low | 0 | 0 | diarylmethane | |
| clofedanol | [no description available] | low | 0 | 0 | diarylmethane;
tertiary amino compound | antitussive |
| clofoctol | [no description available] | low | 0 | 0 | diarylmethane | |
| cloperastine | [no description available] | low | 0 | 0 | diarylmethane | |
| r 59022 | [no description available] | low | 0 | 0 | diarylmethane | |
| dichlorophen | [no description available] | low | 0 | 0 | bridged diphenyl fungicide;
diarylmethane | |
| fendiline | [no description available] | low | 0 | 0 | diarylmethane | |
| 1-[bis(4-fluorophenyl)methyl]-4-(3-phenylprop-2-enyl)piperazine | [no description available] | low | 0 | 0 | diarylmethane | |
| homochlorocyclizine | [no description available] | low | 0 | 0 | diarylmethane | |
| isopropamide iodide | [no description available] | low | 0 | 0 | diarylmethane | |
| lidoflazine | [no description available] | low | 0 | 0 | diarylmethane | |
| lomerizine | [no description available] | low | 0 | 0 | diarylmethane | |
| manidipine | [no description available] | low | 0 | 0 | diarylmethane | |
| meclizine | [no description available] | low | 0 | 0 | diarylmethane | |
| mepenzolate | [no description available] | low | 0 | 0 | diarylmethane | |
| methadone | [no description available] | low | 0 | 0 | benzenes;
diarylmethane;
ketone;
tertiary amino compound | |
| mitotane | [no description available] | low | 0 | 0 | diarylmethane | |
| no 711 | [no description available] | low | 0 | 0 | diarylmethane | |
| oxatomide | [no description available] | low | 0 | 0 | benzimidazoles;
diarylmethane;
N-alkylpiperazine | anti-allergic agent;
anti-inflammatory agent;
geroprotector;
H1-receptor antagonist;
serotonergic antagonist |
| pipenzolate | [no description available] | low | 0 | 0 | diarylmethane | |
| piperidolate | [no description available] | low | 0 | 0 | diarylmethane | |
| proadifen | [no description available] | low | 0 | 0 | diarylmethane | |
| propiverine | [no description available] | low | 0 | 0 | diarylmethane | |
| aurin | [no description available] | low | 0 | 0 | diarylmethane | |
| dpi 201-106 | [no description available] | low | 0 | 0 | diarylmethane | |
| mepenzolate bromide | [no description available] | low | 0 | 0 | diarylmethane | |
| chlorfenethol | [no description available] | low | 0 | 0 | diarylmethane | |
| diphenadione | [no description available] | low | 0 | 0 | beta-triketone;
diarylmethane | |
| phenyltoloxamine | [no description available] | low | 0 | 0 | diarylmethane | |
| n,n,n',n'-tetramethyl-4,4'-methylenedianiline | [no description available] | low | 0 | 0 | diarylmethane | |
| diphenan | [no description available] | low | 0 | 0 | diarylmethane | |
| diphenylmethane | [no description available] | low | 0 | 0 | diarylmethane | |
| 2,2'-methylenebis(4-methyl-6-tert-butylphenol) | [no description available] | low | 0 | 0 | diarylmethane | |
| piperidolate hydrochloride | [no description available] | low | 0 | 0 | diarylmethane | |
| benactyzine | [no description available] | low | 0 | 0 | diarylmethane | |
| prenylamine | [no description available] | low | 0 | 0 | diarylmethane | |
| isomethadone | [no description available] | low | 0 | 0 | diarylmethane | |
| pipradrol | [no description available] | low | 0 | 0 | diarylmethane | |
| normethadone | [no description available] | low | 0 | 0 | diarylmethane | |
| captodiamine | [no description available] | low | 0 | 0 | diarylmethane | |
| methadyl acetate | [no description available] | low | 0 | 0 | diarylmethane | |
| benzomethamine | [no description available] | low | 0 | 0 | diarylmethane | |
| chlorobenzilate | [no description available] | low | 0 | 0 | diarylmethane | |
| dimenhydrinate | [no description available] | low | 0 | 0 | diarylmethane | |
| poldine | [no description available] | low | 0 | 0 | diarylmethane | |
| thiphenamil | [no description available] | low | 0 | 0 | diarylmethane | |
| 4-cumylphenol | [no description available] | low | 0 | 0 | diarylmethane | |
| 4,4'-bisphenol f | [no description available] | low | 0 | 0 | bisphenol;
diarylmethane | environmental food contaminant;
xenoestrogen |
| o,p'-ddt | [no description available] | low | 0 | 0 | diarylmethane | |
| 4,4'-methylene bis(2-methylaniline) | [no description available] | low | 0 | 0 | diarylmethane | |
| dipipanone | [no description available] | low | 0 | 0 | diarylmethane | |
| diphenamid | [no description available] | low | 0 | 0 | diarylmethane | |
| paracymethadol | [no description available] | low | 0 | 0 | diarylmethane | |
| bisphenol a-glycidyl methacrylate | [no description available] | low | 0 | 0 | diarylmethane | |
| azacyclonol | [no description available] | low | 0 | 0 | diarylmethane | |
| dimenoxadol | [no description available] | low | 0 | 0 | diarylmethane | |
| amphenone b | [no description available] | low | 0 | 0 | diarylmethane | |
| propinox | [no description available] | low | 0 | 0 | diarylmethane | |
| embramine | [no description available] | low | 0 | 0 | diarylmethane | |
| chlorophacinone | [no description available] | low | 0 | 0 | beta-triketone;
diarylmethane | |
| aminopentamide | [no description available] | low | 0 | 0 | diarylmethane | |
| octocrylene | [no description available] | low | 0 | 0 | diarylmethane | |
| terodiline | [no description available] | low | 0 | 0 | diarylmethane | |
| tofenacin | [no description available] | low | 0 | 0 | diarylmethane | |
| pipoxolan | [no description available] | low | 0 | 0 | diarylmethane | |
| penfluridol | [no description available] | low | 0 | 0 | diarylmethane | |
| emepronium | [no description available] | low | 0 | 0 | diarylmethane | |
| levomethadyl acetate hydrochloride | [no description available] | low | 0 | 0 | diarylmethane | |
| flumecinol | [no description available] | low | 0 | 0 | diarylmethane | |
| setastine | [no description available] | low | 0 | 0 | diarylmethane | |
| progabide | [no description available] | low | 0 | 0 | diarylmethane | |
| beclobrate | [no description available] | low | 0 | 0 | diarylmethane | |
| cetirizine dihydrochloride | [no description available] | low | 0 | 0 | diarylmethane | |
| niguldipine | [no description available] | low | 0 | 0 | diarylmethane | |
| terfenadine | [no description available] | low | 0 | 0 | diarylmethane | |
| mandrax | [no description available] | low | 0 | 0 | diarylmethane | |
| droprenylamine | [no description available] | low | 0 | 0 | diarylmethane | |
| quifenadine | [no description available] | low | 0 | 0 | diarylmethane | |
| carebastine | [no description available] | low | 0 | 0 | diarylmethane | |
| lercanidipine | [no description available] | low | 0 | 0 | diarylmethane | |
| diphenidol hydrochloride | [no description available] | low | 0 | 0 | diarylmethane | |
| dioxadrol | [no description available] | low | 0 | 0 | diarylmethane | |
| budipine | [no description available] | low | 0 | 0 | diarylmethane | |
| epicainide | [no description available] | low | 0 | 0 | diarylmethane | |
| butinoline | [no description available] | low | 0 | 0 | diarylmethane | |
| denaverine | [no description available] | low | 0 | 0 | diarylmethane | |
| lifarizine | [no description available] | low | 0 | 0 | diarylmethane | |
| fenpiverinium | [no description available] | low | 0 | 0 | diarylmethane | |
| 2,2-methylenebis(4-chloro-3-methyl-isopropylphenol) | [no description available] | low | 0 | 0 | diarylmethane | |
| amperozide | [no description available] | low | 0 | 0 | diarylmethane;
monofluorobenzenes;
N-alkylpiperazine;
secondary carboxamide;
ureas | anxiolytic drug;
dopamine uptake inhibitor;
geroprotector;
second generation antipsychotic;
serotonergic antagonist |
| 2,2'-bisphenol f | [no description available] | low | 0 | 0 | diarylmethane | |
| 3-hydroxy-2,2-diphenylpropanoic acid | [no description available] | low | 0 | 0 | diarylmethane | |
| 1,1-Dichloro-2,2-bis(4-hydroxyphenyl)ethylene | [no description available] | low | 0 | 0 | diarylmethane | |
| bisphenol f diglycidyl ether | [no description available] | low | 0 | 0 | aromatic ether;
diarylmethane;
epoxide | |
| n-(4,4-diphenyl-3-butenyl)nipecotic acid | [no description available] | low | 0 | 0 | diarylmethane | |
| methylene bis(methylanthranilate) | [no description available] | low | 0 | 0 | diarylmethane | |
| tesmilifene | [no description available] | low | 0 | 0 | diarylmethane | |
| pd 123177 | [no description available] | low | 0 | 0 | diarylmethane | |
| bw 373u86 | [no description available] | low | 0 | 0 | diarylmethane | |
| gilutensin hydrochloride | [no description available] | low | 0 | 0 | diarylmethane | |
| 4-(alpha-(4-allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl)-n,n-diethylbenzamide | [no description available] | low | 0 | 0 | diarylmethane | |
| ae0047 | [no description available] | low | 0 | 0 | diarylmethane | |
| lercanidipine hydrochloride | [no description available] | low | 0 | 0 | diarylmethane | |
| cloperastine hydrochloride | [no description available] | low | 0 | 0 | diarylmethane | |
| 1,1,1-trichloro-2-(4-hydroxyphenyl)-2-(4-methoxyphenyl)ethane | [no description available] | low | 0 | 0 | diarylmethane | |
| 2-[(4,6-dimethyl-2-pyrimidinyl)oxy]-3-methoxy-3,3-diphenylpropanoic acid | [no description available] | low | 0 | 0 | diarylmethane | |
| ci 966 | [no description available] | low | 0 | 0 | diarylmethane | |
| Difeterol | [no description available] | low | 0 | 0 | diarylmethane | |
| 1,1-bis(4-hydroxyphenyl)cyclohexane | [no description available] | low | 0 | 0 | diarylmethane | |
| 2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene | [no description available] | low | 0 | 0 | diarylmethane | |
| N-[2-(dimethylamino)ethyl]-2,2-diphenylacetamide | [no description available] | low | 0 | 0 | diarylmethane | |
| propiverine hydrochloride | [no description available] | low | 0 | 0 | diarylmethane | |
| gw 3965 | [no description available] | low | 0 | 0 | diarylmethane | |
| 1,1-Bis(4-hydroxyphenyl)ethane | [no description available] | low | 0 | 0 | diarylmethane | |
| uk 78282 | [no description available] | low | 0 | 0 | diarylmethane | |
| r 59949 | [no description available] | low | 0 | 0 | diarylmethane | |
| 4-[1-(4-hydroxyphenyl)ethenyl]phenol | [no description available] | low | 0 | 0 | diarylmethane | |
| 5-[4-(diphenylmethyl)-1-piperazinyl]-2-(2-methoxyphenyl)-4-oxazolecarbonitrile | [no description available] | low | 0 | 0 | diarylmethane | |
| flunarizine | [no description available] | low | 0 | 0 | diarylmethane | |
| N-[4-[oxo-[(1-oxo-2,2-diphenylethyl)hydrazo]methyl]phenyl]propanamide | [no description available] | low | 0 | 0 | diarylmethane | |
| [4-(diphenylmethyl)-1-piperazinyl]-[5-thiophen-2-yl-7-(trifluoromethyl)-3-pyrazolo[1,5-a]pyrimidinyl]methanone | [no description available] | low | 0 | 0 | diarylmethane | |
| 3-[[[(1-oxo-2,2-diphenylethyl)amino]-sulfanylidenemethyl]amino]benzoic acid | [no description available] | low | 0 | 0 | diarylmethane | |
| 3-bromo-5-[[4-[hydroxy(diphenyl)methyl]-1-piperidinyl]-oxomethyl]-2-pyranone | [no description available] | low | 0 | 0 | diarylmethane | |
| 2-(5-bromo-3-nitro-1,2,4-triazol-1-yl)-N-(diphenylmethyl)acetamide | [no description available] | low | 0 | 0 | diarylmethane | |
| 1,1-bis(4-chlorophenyl)-2-[(3-methoxyphenyl)methylamino]ethanol | [no description available] | low | 0 | 0 | diarylmethane | |
| cinnarizine | [no description available] | low | 0 | 0 | diarylmethane;
N-alkylpiperazine;
olefinic compound | anti-allergic agent;
antiemetic;
calcium channel blocker;
geroprotector;
H1-receptor antagonist;
histamine antagonist;
muscarinic antagonist |
| levocetirizine | [no description available] | low | 0 | 0 | diarylmethane | |
| amn082 | [no description available] | low | 0 | 0 | benzenes;
diamine;
diarylmethane;
secondary amino compound | metabotropic glutamate receptor agonist;
neuroprotective agent |
| N-[2-[tert-butyl(methyl)amino]ethyl]-N-methyl-2,2-diphenylacetamide | [no description available] | low | 0 | 0 | diarylmethane | |
| N-(4-fluorophenyl)-4-[hydroxy(diphenyl)methyl]-1-piperidinecarbothioamide | [no description available] | low | 0 | 0 | diarylmethane | |
| 4-oxo-3-[(1-oxo-2,2-diphenylethyl)amino]-2-sulfanylidene-1H-quinazoline-7-carboxylic acid methyl ester | [no description available] | low | 0 | 0 | diarylmethane | |
| 2,2-diphenylacetic acid (2,6-dimethylphenyl) ester | [no description available] | low | 0 | 0 | diarylmethane | |
| 1-ethyl-3-[(1-oxo-2,2-diphenylethyl)amino]thiourea | [no description available] | low | 0 | 0 | diarylmethane | |
| 2-(phenylmethyl)benzoic acid [2-[4-(difluoromethylthio)anilino]-2-oxoethyl] ester | [no description available] | low | 0 | 0 | diarylmethane | |
| 2-[2-[bis(4-methoxyphenyl)methylidene]hydrazinyl]benzoic acid | [no description available] | low | 0 | 0 | diarylmethane | |
| N-[4-bromo-2-[[(2-hydrazinyl-2-oxoethyl)amino]-phenylmethyl]phenyl]-3-(4-morpholinyl)propanamide | [no description available] | low | 0 | 0 | diarylmethane | |
| N-(4-ethoxyphenyl)-4-[hydroxy(diphenyl)methyl]-1-piperidinecarbothioamide | [no description available] | low | 0 | 0 | diarylmethane | |
| 4-[hydroxy(diphenyl)methyl]-N-(2-phenylethyl)-1-piperidinecarbothioamide | [no description available] | low | 0 | 0 | diarylmethane | |
| 3-(5-chloro-2-hydroxyphenyl)-3-phenyl-N-[(4-propan-2-yloxyphenyl)methyl]propanamide | [no description available] | low | 0 | 0 | diarylmethane | |
| adrafinil | [no description available] | low | 0 | 0 | diarylmethane | |
| zamifenacin | [no description available] | low | 0 | 0 | diarylmethane | |
| 2-(cyclohexylamino)-N-[(diphenylmethylene)amino]propanamide | [no description available] | low | 0 | 0 | diarylmethane | |
| 3-[[4-(diphenylmethyl)-1-piperazinyl]-oxomethyl]-7,8,9,10-tetrahydro-6H-azepino[2,1-b]quinazolin-12-one | [no description available] | low | 0 | 0 | diarylmethane | |
| 3-[bis(4-fluorophenyl)methoxy]-8-methyl-8-azabicyclo[3.2.1]octane | [no description available] | low | 0 | 0 | diarylmethane | |
| flunarizine hydrochloride | [no description available] | low | 0 | 0 | diarylmethane | |
| (2-amino-5-chlorophenyl)(phenyl)methanone oxime | [no description available] | low | 0 | 0 | diarylmethane | |
| imidafenacin | [no description available] | low | 0 | 0 | diarylmethane | |
| 2-(3,3-diphenylpropylamino)acetamide | [no description available] | low | 0 | 0 | diarylmethane | |
| cgk 733 | [no description available] | low | 0 | 0 | diarylmethane | |
| dexniguldipine | [no description available] | low | 0 | 0 | diarylmethane | |
| lu 208075 | [no description available] | low | 0 | 0 | diarylmethane | |
| fesoterodine | [no description available] | low | 0 | 0 | diarylmethane | |
| 3-(diphenylmethylene)-1-[4-(4-phenyl-1-piperazinyl)butyl]pyrrolidine-2,5-dione | [no description available] | low | 0 | 0 | diarylmethane | |
| pnu 200577 | [no description available] | low | 0 | 0 | diarylmethane | |
| gc 1 compound | [no description available] | low | 0 | 0 | diarylmethane | |
| tas 301 | [no description available] | low | 0 | 0 | diarylmethane | |
| 1,5-anhydro-1-(5-(4-ethoxybenzyl)-2-methoxy-4-methylphenyl)-1-thioglucitol | [no description available] | low | 0 | 0 | diarylmethane | |
| [4-(diphenylmethyl)-1-piperazinyl]-(5-methyl-4-nitro-3-isoxazolyl)methanone | [no description available] | low | 0 | 0 | diarylmethane | |
| 1-(1,4-dioxan-2-yl)-N-[[3-(diphenylmethyl)-1,2,4-oxadiazol-5-yl]methyl]-N-methylmethanamine | [no description available] | low | 0 | 0 | diarylmethane | |
| 1-[4-(3-chlorophenyl)-1-piperazinyl]-3-(diphenylmethyl)oxy-2-propanol | [no description available] | low | 0 | 0 | diarylmethane | |
| (8R)-3-[3-[[2-(4-chlorophenoxy)-1-oxoethyl]amino]phenyl]-7-(1-oxo-3,3-diphenylpropyl)-1-oxa-2,7-diazaspiro[4.4]non-2-ene-8-carboxamide | [no description available] | low | 0 | 0 | diarylmethane | |
| 3-(2-hydroxy-4,6-dimethoxyphenyl)-3-(4-methoxyphenyl)-1-(3-methyl-1-piperidinyl)-1-propanone | [no description available] | low | 0 | 0 | diarylmethane | |
| 2-[[[4-[[(diphenylmethyl)amino]-oxomethyl]-1H-imidazol-5-yl]-oxomethyl]amino]acetic acid tert-butyl ester | [no description available] | low | 0 | 0 | diarylmethane;
tert-butyl ester | |
| pf 04971729 | [no description available] | low | 0 | 0 | diarylmethane | |
| ML-210 | [no description available] | low | 0 | 0 | C-nitro compound;
diarylmethane;
isoxazoles;
monochlorobenzenes;
N-acylpiperazine;
N-alkylpiperazine;
tertiary carboxamide | antineoplastic agent;
EC 1.11.1.9 (glutathione peroxidase) inhibitor;
ferroptosis inducer;
prodrug |