Page last updated: 2024-10-23

biperiden and Depression

biperiden has been researched along with Depression in 8 studies

Biperiden: A muscarinic antagonist that has effects in both the central and peripheral nervous systems. It has been used in the treatment of arteriosclerotic, idiopathic, and postencephalitic parkinsonism. It has also been used to alleviate extrapyramidal symptoms induced by phenothiazine derivatives and reserpine.
biperiden : A member of the class of piperidines that is N-propylpiperidine in which the methyl hydrogens have been replaced by hydroxy, phenyl, and 5-norbornen-2-yl groups. A muscarinic antagonist affecting both the central and peripheral nervous systems, it is used in the treatment of all forms of Parkinson's disease.

Depression: Depressive states usually of moderate intensity in contrast with MAJOR DEPRESSIVE DISORDER present in neurotic and psychotic disorders.

Research Excerpts

ExcerptRelevanceReference
" Despite the recent interest in bicaudal C homolog 1 gene (BICC1) as a target for the treatment of depression, the upstream signaling molecules that regulate BICC1 are unknown, and very few studies have addressed the involvement of BICC1 in the antidepressant-like effects of the selective M1-AchR inhibitor, biperiden."3.85The antidepressant-like effects of biperiden may involve BDNF/TrkB signaling-mediated BICC1 expression in the hippocampus and prefrontal cortex of mice. ( Cai, X; Geng, J; Li, C; Li, M; Liu, L; Shen, X; Shi, Y; Sun, X; Wang, C; Wang, J; Yu, H; Zhang, Z; Zhou, D, 2017)
"Marked depression was found in more than half of the patients."1.26The time structure of depressive mood in schizophrenic patients. ( Heger, R; Klicpera, C; Strian, F, 1982)
"The TSH response in the groups with reactive depression, reactive paranoid psychosis, and neurotic depression, respectively, did not differ significantly from that found in controls."1.26Thyrotrophin-releasing hormone (TRH) stimulation test in manic-depressive illness. ( Bjørum, N; Cohn, D; Kirkegaard, C; Lauridsen, UB, 1978)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19905 (62.50)18.7374
1990's2 (25.00)18.2507
2000's0 (0.00)29.6817
2010's1 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Zhou, D1
Zhang, Z1
Liu, L1
Li, C1
Li, M1
Yu, H1
Cai, X1
Sun, X1
Shen, X1
Wang, J1
Geng, J1
Wang, C1
Shi, Y1
Strian, F1
Heger, R1
Klicpera, C1
Posada, IJ1
López-Valdés, E1
Vallejo, AR1
Portera, A1
Higuchi, H1
Kamata, M1
Yoshimoto, M1
Shimisu, T1
Hishikawa, Y1
Kirkegaard, C1
Bjørum, N1
Cohn, D1
Lauridsen, UB1
Ayd, FJ1
Delteil, P1
Decreton, C1
Wieck, HH1

Reviews

1 review available for biperiden and Depression

ArticleYear
Side effects of depot fluphenazines.
    Advances in biochemical psychopharmacology, 1974, Volume: 9, Issue:0

    Topics: Agranulocytosis; Barbiturates; Basal Ganglia Diseases; Benztropine; Biperiden; Delayed-Action Prepar

1974

Trials

1 trial available for biperiden and Depression

ArticleYear
Panic attacks in patients with chronic schizophrenia: a complication of long-term neuroleptic treatment.
    Psychiatry and clinical neurosciences, 1999, Volume: 53, Issue:1

    Topics: Adult; Antipsychotic Agents; Biperiden; Chlorpromazine; Chronic Disease; Depression; Female; Humans;

1999

Other Studies

6 other studies available for biperiden and Depression

ArticleYear
The antidepressant-like effects of biperiden may involve BDNF/TrkB signaling-mediated BICC1 expression in the hippocampus and prefrontal cortex of mice.
    Pharmacology, biochemistry, and behavior, 2017, Volume: 157

    Topics: Animals; Antidepressive Agents; Biperiden; Brain-Derived Neurotrophic Factor; Carbazoles; Depression

2017
The time structure of depressive mood in schizophrenic patients.
    Acta psychiatrica Scandinavica, 1982, Volume: 65, Issue:1

    Topics: Adolescent; Adult; Aged; Biperiden; Depression; Emotions; Female; Humans; Inpatients; Male; Middle A

1982
Extrapyramidal side effects and serotonin syndrome with fluoxetine and biperiden.
    Neurologia (Barcelona, Spain), 1998, Volume: 13, Issue:8

    Topics: Aged; Basal Ganglia Diseases; Biperiden; Depression; Fluoxetine; Humans; Male; Parasympatholytics; S

1998
Thyrotrophin-releasing hormone (TRH) stimulation test in manic-depressive illness.
    Archives of general psychiatry, 1978, Volume: 35, Issue:8

    Topics: Adjustment Disorders; Adult; Age Factors; Aged; Biperiden; Bipolar Disorder; Depression; Female; Hal

1978
[Clinical trial of delayed-action Akinophyl (Akineton)].
    Annales medico-psychologiques, 1972, Volume: 1, Issue:5

    Topics: 1-Propanol; Adjustment Disorders; Adult; Aged; Antidepressive Agents; Antiparkinson Agents; Anxiety

1972
[Actual problems of psychopharmacology in practice and theory].
    Die Medizinische Welt, 1967, Mar-11, Volume: 10

    Topics: Animals; Antidepressive Agents; Biperiden; Depression; Humans; Pharmacology

1967