enkephalin, leucine has been researched along with Depression in 26 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (42.31) | 18.7374 |
| 1990's | 1 (3.85) | 18.2507 |
| 2000's | 7 (26.92) | 29.6817 |
| 2010's | 7 (26.92) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chandra, R; Cheer, JF; Dias, C; Francis, TC; Lobo, MK; Nam, H | 1 |
| Baqi, Y; Correa, M; Freeland, C; Hart, EE; López-Cruz, L; Müller, CE; Nunes, EJ; Randall, PA; Salamone, JD; Yohn, SE | 1 |
| Bilkei-Gorzo, A; Drews, E; Melo, I; Zimmer, A | 1 |
| Cohen, A; Contet, C; George, O; Kieffer, BL; Koebel, P; Koob, GF; Kreifeldt, M; Whitfield, TW | 1 |
| Chen, TC; Hsiao, S; Huang, AC; Kung, JC; Shyu, BC | 1 |
| Burghardt, R; Ehrlich, S; Hamann, I; Infante-Duarte, C; Lehmkuhl, U; Pfeiffer, E; Salbach-Andrae, H; Weiss, D | 1 |
| Bartfai, G; Casanueva, FF; Forti, G; Holliday, KL; Huhtaniemi, IT; Kula, K; Macfarlane, G; McBeth, J; Punab, M; Thomson, W; Vanderschueren, D; Wu, FC | 1 |
| Chen, J; Duman, RS; Nestler, EJ; Neve, R; Newton, SS; Sakai, N; Schlesinger, L; Shirayama, Y; Thome, J; Wallace, TL | 1 |
| Bjørnebekk, A; Brené, S; Mathé, AA | 2 |
| Fagergren, P; Goiny, M; Hurd, YL; Overstreet, DH | 1 |
| Balboni, G; Jutkiewicz, EM; Mosberg, HI; Torregrossa, MM; Watson, SJ; Woods, JH | 1 |
| Bilkei-Gorzo, A; Michel, K; Noble, F; Roques, BP; Zimmer, A | 1 |
| Cork, RC; Crago, BR; Davis, TP; Hameroff, SR; Neuman, C; Scherer, K; Womble, JR | 1 |
| Izquierdo, I; Netto, CA | 1 |
| Coy, DH; Kastin, AJ; Olson, GA; Olson, RD | 1 |
| Bunney, WE; Davis, GC | 1 |
| Gibert-Rahola, J; Maldonado, R; Mico, JA; Roques, BP; Tejedor-Real, P | 1 |
| Roques, BP | 1 |
| Akil, H; Barchas, JD; Elliott, GR; Holman, RB; Watson, SJ | 1 |
| Copolov, D; Smith, GC | 1 |
| Groom, GV | 1 |
| Lideman, RR; Vartanian, ME | 1 |
| Marsden, CD | 1 |
| Krebs, E; Roubicek, J | 1 |
| Vogt, M | 1 |
4 review(s) available for enkephalin, leucine and Depression
| Article | Year |
|---|---|
Behavioral effects after systemic injection of opiate peptides.
Topics: Animals; Avoidance Learning; Behavior; Cats; Chickens; Depression; Dose-Response Relationship, Drug; Drinking Behavior; Endorphins; Enkephalins; Feeding Behavior; Goldfish; Humans; Injections, Intramuscular; Injections, Intraperitoneal; Injections, Intravenous; Injections, Intraventricular; Learning; Memory; Mice; Motor Activity; Rats; Reaction Time; Schizophrenia | 1980 |
Psychopathology and endorphins.
Topics: Bipolar Disorder; Catatonia; Depression; Endorphins; Enkephalins; Humans; Mental Disorders; Narcotic Antagonists; Renal Dialysis; Schizophrenia | 1980 |
Novel approaches to targeting neuropeptide systems.
Topics: Animals; Anxiety; Depression; Dopamine; Enkephalins; Enzyme Inhibitors; Humans; Metalloendopeptidases; Mice; Neuropeptides; Pain; Protease Inhibitors; Receptors, Cholecystokinin; Receptors, Opioid; Reward; Sincalide; Substance-Related Disorders | 2000 |
A review of the relationship between endocrinopathy and depression or antidepressant drugs, with particular respect to novel theories involving the opiate receptor.
Topics: Circadian Rhythm; Clomipramine; Depression; Dibenzazepines; Endorphins; Enkephalins; Hormones; Humans; Pituitary Hormones, Anterior; Receptors, Opioid | 1977 |
2 trial(s) available for enkephalin, leucine and Depression
| Article | Year |
|---|---|
Doxepin effects on chronic pain, depression and plasma opioids.
Topics: Adult; Aged; beta-Endorphin; Chronic Disease; Depression; Double-Blind Method; Doxepin; Endorphins; Enkephalins; Female; Humans; Male; Middle Aged; Pain; Placebos; Random Allocation; Sensory Thresholds; Sleep | 1982 |
EEG and clinical profile of a synthetic analogue of methionine-enkephalin - FK 33-824.
Topics: Adult; Behavior; Clinical Trials as Topic; Depression; Double-Blind Method; Electroencephalography; Endorphins; Enkephalins; Humans; Male; Middle Aged; Placebos; Schizophrenia | 1979 |
20 other study(ies) available for enkephalin, leucine and Depression
| Article | Year |
|---|---|
Reduced nucleus accumbens enkephalins underlie vulnerability to social defeat stress.
Topics: Analgesics, Opioid; Animals; Behavior, Animal; Benzamides; Depression; Disease Models, Animal; Dominance-Subordination; Enkephalins; Mice; Mice, Inbred C57BL; Nucleus Accumbens; Piperazines; Receptors, Opioid, delta; Stress, Psychological | 2019 |
Effort-related motivational effects of the VMAT-2 inhibitor tetrabenazine: implications for animal models of the motivational symptoms of depression.
Topics: Adenosine A2 Receptor Antagonists; Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents, Second-Generation; Behavior, Animal; Bupropion; Conditioning, Operant; Depression; Disease Models, Animal; Dopamine; Dopamine and cAMP-Regulated Phosphoprotein 32; Enkephalins; Feeding Behavior; Immunohistochemistry; Male; Microdialysis; Motivation; Nucleus Accumbens; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Substance P; Tetrabenazine; Vesicular Monoamine Transport Proteins; Xanthines | 2013 |
Enkephalin knockout male mice are resistant to chronic mild stress.
Topics: Animals; Anxiety; Corticosterone; Depression; Enkephalins; Hypothalamus; Male; Maze Learning; Mice; Mice, Inbred C57BL; Paraventricular Hypothalamic Nucleus; Protein Precursors; Stress, Psychological | 2014 |
Virus-mediated shRNA knockdown of prodynorphin in the rat nucleus accumbens attenuates depression-like behavior and cocaine locomotor sensitization.
Topics: Analysis of Variance; Animals; Anxiety; Cocaine; Dependovirus; Depression; Enkephalins; Gene Expression Regulation; Gene Knockdown Techniques; Genetic Vectors; In Situ Hybridization; Locomotion; Maze Learning; Nucleus Accumbens; Protein Precursors; Rats; Rats, Wistar; RNA, Small Interfering | 2014 |
Anxiety- and depressive-like responses and c-fos activity in preproenkephalin knockout mice: oversensitivity hypothesis of enkephalin deficit-induced posttraumatic stress disorder.
Topics: Animals; Anxiety; Avoidance Learning; Behavior, Animal; Brain; Depression; Disease Models, Animal; Electroshock; Enkephalins; Male; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Knockout; Models, Biological; Protein Precursors; Proto-Oncogene Proteins c-fos; Stress Disorders, Post-Traumatic; Tissue Distribution | 2010 |
Preproenkephalin expression in peripheral blood mononuclear cells of acutely underweight and recovered patients with anorexia nervosa.
Topics: Adolescent; Adult; Anorexia Nervosa; Anxiety; Basal Metabolism; Depression; Enkephalins; Female; Gene Expression; Humans; Leptin; Leukocytes, Mononuclear; Obsessive-Compulsive Disorder; Protein Precursors; Psychiatric Status Rating Scales; Severity of Illness Index; Stress, Psychological; Thinness | 2010 |
Investigating the role of pain-modulating pathway genes in musculoskeletal pain.
Topics: Adult; Aged; Anxiety; Cohort Studies; Comorbidity; Depression; Enkephalins; Female; Genotype; Humans; Kv Channel-Interacting Proteins; Male; Middle Aged; Musculoskeletal Pain; Polymorphism, Single Nucleotide; Protein Precursors; Receptors, Opioid, kappa; Repressor Proteins | 2013 |
Inhibition of cAMP response element-binding protein or dynorphin in the nucleus accumbens produces an antidepressant-like effect.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Cyclic AMP Response Element-Binding Protein; Depression; Dynorphins; Enkephalins; Helplessness, Learned; Immunohistochemistry; Male; Mice; Mice, Transgenic; Mutation; Naltrexone; Nucleus Accumbens; Prosencephalon; Protein Precursors; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa | 2002 |
The antidepressant effect of running is associated with increased hippocampal cell proliferation.
Topics: Analysis of Variance; Animals; Antidepressive Agents; Behavior, Animal; Body Weight; Brain-Derived Neurotrophic Factor; Bromodeoxyuridine; Cell Count; Cell Proliferation; Depression; Disease Models, Animal; Dynorphins; Enkephalins; Freezing Reaction, Cataleptic; Hippocampus; Immunohistochemistry; In Situ Hybridization; Male; Rats; Rats, Inbred Strains; RNA, Messenger; Running; Substance P | 2005 |
Blunted response to cocaine in the Flinders hypercholinergic animal model of depression.
Topics: Acetylcholine; Animals; Chromatography, High Pressure Liquid; Cocaine; Cocaine-Related Disorders; Corpus Striatum; Depression; Disease Models, Animal; Dopamine; Dopamine Uptake Inhibitors; Enkephalins; In Situ Hybridization; Male; Microdialysis; Motor Activity; Nucleus Accumbens; Protein Precursors; Rats; RNA, Messenger | 2005 |
Running has differential effects on NPY, opiates, and cell proliferation in an animal model of depression and controls.
Topics: Analysis of Variance; Animals; Bromodeoxyuridine; Cell Count; Cell Proliferation; Depression; Disease Models, Animal; Dynorphins; Enkephalins; Exercise Therapy; Hippocampus; Immunohistochemistry; In Situ Hybridization; Male; Neuropeptide Y; Rats; Rats, Inbred Strains; Running | 2006 |
Peptidic delta opioid receptor agonists produce antidepressant-like effects in the forced swim test and regulate BDNF mRNA expression in rats.
Topics: Adamantane; Animals; Antidepressive Agents; Autoradiography; Behavior, Animal; Brain-Derived Neurotrophic Factor; Depression; Dipeptides; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Interactions; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Gene Expression Regulation; Immobility Response, Tonic; In Situ Hybridization; Male; Oligopeptides; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; RNA, Messenger; Swimming; Tetrahydroisoquinolines | 2006 |
Preproenkephalin knockout mice show no depression-related phenotype.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Depression; Disease Models, Animal; Disulfides; Dose-Response Relationship, Drug; Enkephalins; Enzyme Inhibitors; Hindlimb Suspension; Immobility Response, Tonic; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Knockout; Motor Activity; Nialamide; Phenotype; Phenylalanine; Protein Precursors; Swimming; Vocalization, Animal | 2007 |
Amnesia as a major side effect of electroconvulsive shock: the possible involvement of hypothalamic opioid systems.
Topics: Amnesia; Animals; Brain Chemistry; Catecholamines; Depression; Electroconvulsive Therapy; Endorphins; Enkephalins; Humans; Rats | 1984 |
Implication of endogenous opioid system in the learned helplessness model of depression.
Topics: Animals; Antidepressive Agents, Tricyclic; Avoidance Learning; Depression; Electroshock; Endorphins; Enkephalins; Helplessness, Learned; Hydroxamic Acids; Imipramine; Male; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Neprilysin; Phenylalanine; Protease Inhibitors; Rats; Rats, Wistar | 1995 |
Behavioral neurochemistry: neuroregulators and behavioral states.
Topics: Animals; Behavior; Cell Communication; Depression; Endorphins; Enkephalins; Hormones; Humans; Mental Disorders; Nervous System Physiological Phenomena; Neurons; Neurotransmitter Agents; Schizophrenia; Synapses | 1978 |
Brain amines and peptides--their relevance to psychiatry.
Topics: Amines; Animals; Behavior, Animal; Brain; Depression; Dopamine; Endorphins; Enkephalins; Humans; Mental Disorders; Neurons; Neurotransmitter Agents; Peptides; Schizophrenia | 1979 |
[Opiate receptors and endogenous morphines: a new approach to the study of the brain].
Topics: Adenylyl Cyclases; Animals; Brain; Brain Chemistry; Cyclic AMP; Depression; Endorphins; Enkephalins; Haplorhini; Humans; Pituitary Gland; Rats; Receptors, Opioid; Schizophrenia | 1978 |
The emotion of pain and its chemistry.
Topics: Animals; Biogenic Amines; Brain; Brain Chemistry; Cerebral Cortex; Chemical Phenomena; Chemistry; Depression; Emotions; Endorphins; Enkephalins; Humans; Mice; Narcotics; Pain; Receptors, Opioid; Sensory Thresholds | 1979 |
The impact on neurology of 40 years' advances in pharmacology.
Topics: Acetylcholine; Chemical Phenomena; Chemistry; Chlorpromazine; Depression; Endorphins; Enkephalins; Humans; Nervous System Diseases; Penicillins; Schizophrenia; Sulfonamides | 1979 |