finasteride and Depression

finasteride has been researched along with Depression in 29 studies

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's7 (24.14)29.6817
2010's17 (58.62)24.3611
2020's5 (17.24)2.80

Authors

AuthorsStudies
Fall, K; Garcia-Argibay, M; Hiyoshi, A; Montgomery, S1
Cantrell, MA; Dyson, TE; Lund, BC1
Borgo, F; Cavaletti, G; Diviccaro, S; Falvo, E; Giatti, S; Macandog, AD; Melcangi, RC1
Basaria, S; Bhojani, N; Cone, EB; Marchese, M; Nguyen, DD; Paciotti, M; Trinh, QD1
Anderson, KK; Dixon, S; Hayward, J; McArthur, E; Ordon, M; Welk, B1
Gong, J; Guo, Y; Jiang, XY; Li, L; Li, YF; Sun, LJ; Sun, SZ; Wang, HL; Wang, W; Zhang, LM; Zhang, YZ1
Kaplan, SA1
Karakas, SE1
Schmutz, JL1
Bergfeld, W; Murad, A1
Diviccaro, S; Giatti, S; Melcangi, RC; Panzica, G1
Barcella, M; Borghi, E; Borgo, F; Diviccaro, S; Garcia-Segura, LM; Giatti, S; Melcangi, RC; Trejo, JL1
Sasibhushana, RB; Shankaranarayana Rao, BS; Srikumar, BN1
Diaconu, CC; Georgescu, SR; Mitran, CI; Mitran, MI; Motofei, IG; Paunica, S; Rowland, DL; Sarbu, MI; Stoian, AP; Tampa, M1
Abbiati, F; Calabrese, D; Caruso, D; Cavaletti, G; Giatti, S; Melcangi, RC; Piazza, F1
Abbiati, F; Caruso, D; Cavaletti, G; Fusco, L; Giatti, S; Melcangi, RC; Romano, S1
Bortolato, M; Garcia-Segura, LM; Melcangi, RC; Traish, AM; Zitzmann, M1
Ganzer, CA; Jacobs, AR1
Barlow, WE; Goodman, PJ; Hershman, DL; Minasian, LM; Ramsey, SD; Tangen, CM; Thompson, IM; Till, C; Unger, JM; Wright, JD1
Gass, P; Römer, B1
Beckley, EH; Finn, DA; Scibelli, AC1
Guay, AT; Hansen, ML; Hassani, J; Traish, AM; Zitzmann, M1
Altomare, G; Capella, GL1
Frye, CA; Walf, AA2
Frye, CA; Sumida, K; Walf, AA1
Beadles-Bohling, AS; Beckley, EH; Finn, DA; Ford, MM; Gililland, KR; Gorin-Meyer, RE; Wiren, KM1
Habibollahi, P; Mualeki, A; Pourandarjani, R; Rahimi-Ardabili, B1
Beckley, EH; Finn, DA1

Reviews

6 review(s) available for finasteride and Depression

ArticleYear
5-alpha-reductase inhibitor treatment for frontal fibrosing alopecia: an evidence-based treatment update.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2018, Volume: 32, Issue:8

    Topics: 5-alpha Reductase Inhibitors; Alopecia; Breast Neoplasms; Depression; Dutasteride; Evidence-Based Medicine; Female; Fibrosis; Finasteride; Forehead; Hair; Humans; Scalp; Sexual Dysfunction, Physiological

2018
Post-finasteride syndrome and post-SSRI sexual dysfunction: two sides of the same coin?
    Endocrine, 2018, Volume: 61, Issue:2

    Topics: Alopecia; Antidepressive Agents; Depression; Female; Finasteride; Humans; Iatrogenic Disease; Libido; Male; Selective Serotonin Reuptake Inhibitors; Sexual Dysfunction, Physiological; Syndrome

2018
Finasteride and androgenic alopecia; from therapeutic options to medical implications.
    The Journal of dermatological treatment, 2020, Volume: 31, Issue:4

    Topics: 5-alpha Reductase Inhibitors; Alopecia; Brain; Depression; Female; Finasteride; Humans; Male

2020
Adverse effects of 5α-reductase inhibitors: What do we know, don't know, and need to know?
    Reviews in endocrine & metabolic disorders, 2015, Volume: 16, Issue:3

    Topics: 5-alpha Reductase Inhibitors; Alopecia; Animals; Central Nervous System; Cholestenone 5 alpha-Reductase; Cognition Disorders; Depression; Diabetes Mellitus; Dutasteride; Finasteride; Humans; Male; Prostatic Hyperplasia; Prostatic Neoplasms; Psychoses, Substance-Induced; Sexual Dysfunction, Physiological; Steroids

2015
Adverse side effects of 5α-reductase inhibitors therapy: persistent diminished libido and erectile dysfunction and depression in a subset of patients.
    The journal of sexual medicine, 2011, Volume: 8, Issue:3

    Topics: 5-alpha Reductase Inhibitors; Depression; Erectile Dysfunction; Finasteride; Humans; Libido; Male

2011
A new look at the 5alpha-reductase inhibitor finasteride.
    CNS drug reviews, 2006,Spring, Volume: 12, Issue:1

    Topics: Alcohol-Related Disorders; Cholestenone 5 alpha-Reductase; Depression; Enzyme Inhibitors; Finasteride; Models, Biological; Seizures; Sexual Behavior

2006

Trials

1 trial(s) available for finasteride and Depression

ArticleYear
Finasteride induced depression: a prospective study.
    BMC clinical pharmacology, 2006, Oct-07, Volume: 6

    Topics: Adult; Alopecia; Anxiety; Depression; Enzyme Inhibitors; Finasteride; Humans; Male; Prospective Studies; Surveys and Questionnaires

2006

Other Studies

22 other study(ies) available for finasteride and Depression

ArticleYear
Association of 5α-Reductase Inhibitors With Dementia, Depression, and Suicide.
    JAMA network open, 2022, 12-01, Volume: 5, Issue:12

    Topics: 5-alpha Reductase Inhibitors; Alzheimer Disease; Antineoplastic Agents; Cohort Studies; Dementia, Vascular; Depression; Dutasteride; Finasteride; Humans; Male; Prostatic Hyperplasia; Retrospective Studies; Suicide

2022
Lack of Association between 5α-Reductase Inhibitors and Depression.
    The Journal of urology, 2020, Volume: 204, Issue:4

    Topics: 5-alpha Reductase Inhibitors; Aged; Depression; Dutasteride; Finasteride; Humans; Male; Middle Aged; Prostatic Hyperplasia; Retrospective Studies

2020
Alterations of gut microbiota composition in post-finasteride patients: a pilot study.
    Journal of endocrinological investigation, 2021, Volume: 44, Issue:6

    Topics: 5-alpha Reductase Inhibitors; Alopecia; Biodiversity; Cognitive Dysfunction; Correlation of Data; Depression; Drug-Related Side Effects and Adverse Reactions; Finasteride; Gastrointestinal Microbiome; Humans; Male; Middle Aged; Physical Functional Performance; RNA, Ribosomal, 16S; Sequence Analysis, DNA; Sexual Dysfunction, Physiological

2021
Investigation of Suicidality and Psychological Adverse Events in Patients Treated With Finasteride.
    JAMA dermatology, 2021, 01-01, Volume: 157, Issue:1

    Topics: 5-alpha Reductase Inhibitors; Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Age Factors; Alopecia; Anxiety; Case-Control Studies; Depression; Female; Finasteride; Humans; Male; Pharmacovigilance; Prostatic Hyperplasia; Sex Factors; Suicide; Young Adult

2021
Association of Suicidality and Depression With 5α-Reductase Inhibitors.
    JAMA internal medicine, 2017, 05-01, Volume: 177, Issue:5

    Topics: 5-alpha Reductase Inhibitors; Aged; Aged, 80 and over; Case-Control Studies; Depression; Depressive Disorder; Dutasteride; Finasteride; Humans; Male; Ontario; Prostatic Hyperplasia; Retrospective Studies; Risk Factors; Self-Injurious Behavior; Suicidal Ideation; Suicide; Time Factors

2017
Overexpression of the 18 kDa translocator protein (TSPO) in the hippocampal dentate gyrus produced anxiolytic and antidepressant-like behavioural effects.
    Neuropharmacology, 2017, Volume: 125

    Topics: 5-alpha Reductase Inhibitors; Animals; Anxiety; Dentate Gyrus; Depression; Finasteride; Genetic Vectors; Isoquinolines; Lentivirus; Male; Mice, Inbred ICR; Motor Activity; Pregnanolone; Psychotropic Drugs; Receptors, GABA

2017
Re: Association of Suicidality and Depression with 5α-Reductase Inhibitors.
    The Journal of urology, 2017, Volume: 198, Issue:5

    Topics: 5-alpha Reductase Inhibitors; Depression; Finasteride; Humans; Oxidoreductases; Suicide

2017
Women Also Use 5α-Reductase Inhibitors.
    JAMA internal medicine, 2017, 11-01, Volume: 177, Issue:11

    Topics: 5-alpha Reductase Inhibitors; Depression; Female; Finasteride; Humans; Oxidoreductases; Suicide

2017
[Depression and suicidal thoughts associated with finasteride].
    Annales de dermatologie et de venereologie, 2018, Volume: 145, Issue:2

    Topics: 5-alpha Reductase Inhibitors; Depression; Finasteride; Humans; Male; Suicidal Ideation

2018
Treatment of male rats with finasteride, an inhibitor of 5alpha-reductase enzyme, induces long-lasting effects on depressive-like behavior, hippocampal neurogenesis, neuroinflammation and gut microbiota composition.
    Psychoneuroendocrinology, 2019, Volume: 99

    Topics: 5-alpha Reductase Inhibitors; Animals; Astrocytes; Brain; Cholestenone 5 alpha-Reductase; Dentate Gyrus; Depression; Finasteride; Gastrointestinal Microbiome; Hippocampus; Male; Neurogenesis; Neuroimmunomodulation; Neurons; Rats; Rats, Sprague-Dawley; Steroids; Substance Withdrawal Syndrome

2019
Repeated finasteride administration induces depression-like behavior in adult male rats.
    Behavioural brain research, 2019, 06-03, Volume: 365

    Topics: 5-alpha Reductase Inhibitors; Animals; Depression; Depressive Disorder; Enzyme Inhibitors; Finasteride; Grooming; Male; Rats; Rats, Wistar; Swimming

2019
Neuroactive steroid levels are modified in cerebrospinal fluid and plasma of post-finasteride patients showing persistent sexual side effects and anxious/depressive symptomatology.
    The journal of sexual medicine, 2013, Volume: 10, Issue:10

    Topics: 5-alpha Reductase Inhibitors; Adult; Alopecia; Anxiety; Biomarkers; Case-Control Studies; Chromatography, Liquid; Depression; Drug Administration Schedule; Female; Finasteride; Humans; Male; Sexual Behavior; Steroids; Tandem Mass Spectrometry; Time Factors; Treatment Outcome

2013
Patients treated for male pattern hair with finasteride show, after discontinuation of the drug, altered levels of neuroactive steroids in cerebrospinal fluid and plasma.
    The Journal of steroid biochemistry and molecular biology, 2015, Volume: 146

    Topics: 20-alpha-Dihydroprogesterone; Adult; Alopecia; Anxiety Disorders; Case-Control Studies; Depression; Finasteride; Humans; Male; Pregnenolone; Progesterone; Sexual Dysfunctions, Psychological; Steroids

2015
Emotional Consequences of Finasteride: Fool's Gold.
    American journal of men's health, 2018, Volume: 12, Issue:1

    Topics: Adult; Age Factors; Alopecia; Anxiety; Cross-Sectional Studies; Depression; Drug-Related Side Effects and Adverse Reactions; Emotions; Female; Finasteride; Humans; Incidence; Male; Patient Reported Outcome Measures; Pharmacovigilance; Risk Assessment; Sex Factors; Surveys and Questionnaires; Syndrome; United States; Young Adult

2018
Long-term Consequences of Finasteride vs Placebo in the Prostate Cancer Prevention Trial.
    Journal of the National Cancer Institute, 2016, Volume: 108, Issue:12

    Topics: 5-alpha Reductase Inhibitors; Administrative Claims, Healthcare; Aged; Clinical Trials as Topic; Depression; Finasteride; Follow-Up Studies; Humans; Lower Urinary Tract Symptoms; Male; Medical Record Linkage; Medicare; Middle Aged; Prostatic Neoplasms; Protective Factors; Risk Assessment; Risk Factors; Time Factors; United States

2016
Finasteride-induced depression: new insights into possible pathomechanisms.
    Journal of cosmetic dermatology, 2010, Volume: 9, Issue:4

    Topics: 5-alpha Reductase Inhibitors; Animals; Depression; Finasteride; Humans; Limbic System; Mice

2010
Progesterone receptor antagonist CDB-4124 increases depression-like behavior in mice without affecting locomotor ability.
    Psychoneuroendocrinology, 2011, Volume: 36, Issue:6

    Topics: Animals; Depression; Depression, Postpartum; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Finasteride; Locomotion; Mice; Mice, Inbred DBA; Mifepristone; Norpregnadienes; Premenstrual Syndrome; Progesterone; Receptors, Progesterone; Single-Blind Method; Swimming

2011
Depression circumstantially related to the administration of finasteride for androgenetic alopecia.
    The Journal of dermatology, 2002, Volume: 29, Issue:10

    Topics: 5-alpha Reductase Inhibitors; Alopecia; Depression; Enzyme Inhibitors; Female; Finasteride; Humans; Male; Middle Aged

2002
Hippocampal 3alpha,5alpha-THP may alter depressive behavior of pregnant and lactating rats.
    Pharmacology, biochemistry, and behavior, 2004, Volume: 78, Issue:3

    Topics: Animals; Depression; Female; Finasteride; Hippocampus; Lactation; Pregnancy; Pregnancy, Animal; Pregnanolone; Rats; Rats, Long-Evans; Swimming

2004
Inhibiting 5alpha-reductase in the amygdala attenuates antianxiety and antidepressive behavior of naturally receptive and hormone-primed ovariectomized rats.
    Psychopharmacology, 2006, Volume: 186, Issue:3

    Topics: 5-alpha Reductase Inhibitors; Amygdala; Animals; Anxiety; Behavior, Animal; Depression; Enzyme Inhibitors; Estradiol; Female; Finasteride; Ovariectomy; Progesterone; Rats; Rats, Long-Evans

2006
Inhibition of progesterone metabolism mimics the effect of progesterone withdrawal on forced swim test immobility.
    Pharmacology, biochemistry, and behavior, 2007, Volume: 87, Issue:4

    Topics: 5-alpha Reductase Inhibitors; Animals; Depression; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Finasteride; Mice; Mice, Inbred DBA; Motor Activity; Pregnanolone; Progesterone; Substance Withdrawal Syndrome; Swimming

2007
Changes in progesterone metabolites in the hippocampus can modulate open field and forced swim test behavior of proestrous rats.
    Hormones and behavior, 2002, Volume: 41, Issue:3

    Topics: Animals; Anxiety; Depression; Enzyme Inhibitors; Exploratory Behavior; Female; Finasteride; Hippocampus; Male; Posture; Pregnanolone; Proestrus; Progesterone; Progestins; Rats; Rats, Long-Evans; Sex Characteristics; Sexual Behavior, Animal; Swimming

2002