emodin has been researched along with Depression in 3 studies
Emodin: Purgative anthraquinone found in several plants, especially RHAMNUS PURSHIANA. It was formerly used as a laxative, but is now used mainly as a tool in toxicity studies.
emodin : A trihydroxyanthraquinone that is 9,10-anthraquinone which is substituted by hydroxy groups at positions 1, 3, and 8 and by a methyl group at position 6. It is present in the roots and barks of numerous plants (particularly rhubarb and buckthorn), moulds, and lichens. It is an active ingredient of various Chinese herbs.
Depression: Depressive states usually of moderate intensity in contrast with MAJOR DEPRESSIVE DISORDER present in neurotic and psychotic disorders.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Depression is a complex neuropsychiatric disease involved multiple targets and signaling pathways." | 1.62 | Mechanistic insights into the anti-depressant effect of emodin: an integrated systems pharmacology study and experimental validation. ( Fang, YY; Su, HF; Tian, Q; Wang, XM; Ye, CY; Zeng, P; Zhang, T, 2021) |
| "Treatment with emodin normalized the change of plasma corticosterone level, which demonstrated that emodin could partially restore CUMS-induced HPA axis impairments." | 1.40 | Emodin opposes chronic unpredictable mild stress induced depressive-like behavior in mice by upregulating the levels of hippocampal glucocorticoid receptor and brain-derived neurotrophic factor. ( Fu, Q; Li, M; Li, S; Li, Y; Ma, S; Xue, J, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 2 (66.67) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, Y | 1 |
| Peng, J | 1 |
| Leng, Q | 1 |
| Tian, Y | 1 |
| Wu, X | 1 |
| Tan, R | 1 |
| Zeng, P | 1 |
| Wang, XM | 1 |
| Ye, CY | 1 |
| Su, HF | 1 |
| Fang, YY | 1 |
| Zhang, T | 1 |
| Tian, Q | 1 |
| Li, M | 1 |
| Fu, Q | 1 |
| Li, Y | 1 |
| Li, S | 1 |
| Xue, J | 1 |
| Ma, S | 1 |
3 other studies available for emodin and Depression
| Article | Year |
|---|---|
Effects of Aloe-Emodin on the Expression of Brain Aquaporins and Secretion of Neurotrophic Factors in a Rat Model of Post-Stroke Depression.
Topics: Aloe; Animals; Brain; Brain-Derived Neurotrophic Factor; Depression; Emodin; Prospective Studies; Ra | 2023 |
Mechanistic insights into the anti-depressant effect of emodin: an integrated systems pharmacology study and experimental validation.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Depression; Emodin; Gene Ontology; Genome; Inflamm | 2021 |
Emodin opposes chronic unpredictable mild stress induced depressive-like behavior in mice by upregulating the levels of hippocampal glucocorticoid receptor and brain-derived neurotrophic factor.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Brain-Derived Neurotrophic Factor; Corticosterone; | 2014 |