Page last updated: 2024-10-27

fentanyl and Depression

fentanyl has been researched along with Depression in 8 studies

Fentanyl: A potent narcotic analgesic, abuse of which leads to habituation or addiction. It is primarily a mu-opioid agonist. Fentanyl is also used as an adjunct to general anesthetics, and as an anesthetic for induction and maintenance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1078)
fentanyl : A monocarboxylic acid amide resulting from the formal condensation of the aryl amino group of N-phenyl-1-(2-phenylethyl)piperidin-4-amine with propanoic acid.

Depression: Depressive states usually of moderate intensity in contrast with MAJOR DEPRESSIVE DISORDER present in neurotic and psychotic disorders.

Research Excerpts

ExcerptRelevanceReference
"Our aim was to find out whether intravenous fentanyl was effective in reducing the pain of first-trimester abortion."9.09A randomized controlled trial of fentanyl for abortion pain. ( Rawling, MJ; Wiebe, ER, 2001)
" Although this article focuses on serotonin syndrome as a result of an adverse interaction of selective serotonin reuptake inhibitors (SSRI) and fentanyl, it is important for not only anesthesia professionals, but all clinicians--such as those in emergency medicine and critical care--to be aware of this syndrome and its management."7.80Serotonin syndrome: fentanyl and selective serotonin reuptake inhibitor interactions. ( Greenier, E; Lukyanova, V; Reede, L, 2014)
"Our aim was to find out whether intravenous fentanyl was effective in reducing the pain of first-trimester abortion."5.09A randomized controlled trial of fentanyl for abortion pain. ( Rawling, MJ; Wiebe, ER, 2001)
" Although this article focuses on serotonin syndrome as a result of an adverse interaction of selective serotonin reuptake inhibitors (SSRI) and fentanyl, it is important for not only anesthesia professionals, but all clinicians--such as those in emergency medicine and critical care--to be aware of this syndrome and its management."3.80Serotonin syndrome: fentanyl and selective serotonin reuptake inhibitor interactions. ( Greenier, E; Lukyanova, V; Reede, L, 2014)
"Mu-opioid receptor availability in vivo (nondisplaceable binding potential, or BP(ND)) was measured with positron emission tomography and the selective radiotracer [(11)C]carfentanil during neutral and sustained sadness states in 18 unmedicated female patients with borderline personality disorder and 14 healthy female comparison subjects."3.76Dysregulation of regional endogenous opioid function in borderline personality disorder. ( Koeppe, RA; Love, TM; Prossin, AR; Silk, KR; Zubieta, JK, 2010)
"Head and neck cancers (HNC) represent 5% of all malignancies worldwide with about 180,000 cancer deaths per year."2.66Is pain part of a systemic syndrome in head and neck cancer? ( Argenone, A; Bossi, P; Depenni, R; Ghiani, M, 2020)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (37.50)29.6817
2010's4 (50.00)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Bossi, P1
Ghiani, M1
Argenone, A1
Depenni, R1
Guitart, J1
Vargas, MI1
De Sanctis, V1
Folch, J1
Salazar, R1
Fuentes, J1
Coma, J1
Ferreras, J1
Moya, J1
Tomás, A1
Estivill, P1
Rodelas, F1
Jiménez, AJ1
Sanz, A1
Greenier, E1
Lukyanova, V1
Reede, L1
Prossin, AR2
Koch, AE1
Campbell, PL1
Barichello, T1
Zalcman, SS1
Zubieta, JK2
Love, TM1
Koeppe, RA1
Silk, KR1
Carter, AC1
Nicholas, JJ1
Lalley, PM1
Rawling, MJ1
Wiebe, ER1

Reviews

1 review available for fentanyl and Depression

ArticleYear
Is pain part of a systemic syndrome in head and neck cancer?
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2020, Volume: 28, Issue:2

    Topics: Analgesics, Opioid; Breakthrough Pain; Cancer Pain; Depression; Exercise; Fatigue; Fentanyl; Head an

2020

Trials

1 trial available for fentanyl and Depression

ArticleYear
A randomized controlled trial of fentanyl for abortion pain.
    American journal of obstetrics and gynecology, 2001, Volume: 185, Issue:1

    Topics: Abortion, Induced; Adult; Analgesics, Opioid; Anxiety; Depression; Female; Fentanyl; Humans; Pain; P

2001

Other Studies

6 other studies available for fentanyl and Depression

ArticleYear
Breakthrough Pain Management with Sublingual Fentanyl Tablets in Patients with Cancer: Age Subgroup Analysis of a Multicenter Prospective Study.
    Drugs in R&D, 2017, Volume: 17, Issue:3

    Topics: Administration, Sublingual; Age Factors; Aged; Analgesics, Opioid; Anxiety; Breakthrough Pain; Cance

2017
Serotonin syndrome: fentanyl and selective serotonin reuptake inhibitor interactions.
    AANA journal, 2014, Volume: 82, Issue:5

    Topics: Adult; Anesthesia; Back Pain; Carpal Tunnel Syndrome; Depression; Drug Interactions; Female; Fentany

2014
Experimental sadness induces relevant interactions between central endogenous opioid activation and plasma IL-18 concentrations in depressed volunteers.
    Molecular psychiatry, 2016, Volume: 21, Issue:2

    Topics: Depression; Fentanyl; Humans; Interleukin-18; Receptors, Opioid, mu

2016
Dysregulation of regional endogenous opioid function in borderline personality disorder.
    The American journal of psychiatry, 2010, Volume: 167, Issue:8

    Topics: Adult; Borderline Personality Disorder; Brain; Carbon Radioisotopes; Depression; Emotions; Endorphin

2010
The importance of the complete history in the discovery of a potential suicide: a case report.
    Archives of physical medicine and rehabilitation, 2003, Volume: 84, Issue:3

    Topics: Acetates; Amines; Analgesics, Opioid; Anti-Anxiety Agents; Anti-Bacterial Agents; Cyclohexanecarboxy

2003
D1-dopamine receptor blockade slows respiratory rhythm and enhances opioid-mediated depression.
    Respiratory physiology & neurobiology, 2005, Jan-15, Volume: 145, Issue:1

    Topics: Action Potentials; Animals; Benzazepines; Cats; Depression; Dose-Response Relationship, Drug; Drug A

2005