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desmethylmianserin and Depression

desmethylmianserin has been researched along with Depression in 6 studies

*Depression: Depressive states usually of moderate intensity in contrast with MAJOR DEPRESSIVE DISORDER present in neurotic and psychotic disorders. [MeSH]

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Buist, A; Dennerstein, L; Norman, TR1
Fukushima, Y; Kaneko, S; Kondo, T; Otani, K; Sasa, H1
Fukushima, Y; Kaneko, S; Mihara, K; Okada, M; Otani, K; Tanaka, O1
Bertilsson, L; Fukushima, Y; Kaneko, S; Mihara, K; Otani, K; Tybring, G1
Kaneko, S; Mihara, K; Otani, K; Suzuki, A; Svensson, JO; Tybring, G; Yasui, N1
Hand, TH; Marek, GJ; Seiden, LS1

Trials

1 trial(s) available for desmethylmianserin and Depression

ArticleYear
Enantioselective determination of mianserin and its desmethyl metabolite in plasma during treatment of depressed Japanese patients.
    Therapeutic drug monitoring, 1995, Volume: 17, Issue:5

    Topics: Adult; Aged; Antidepressive Agents, Second-Generation; Chromatography, High Pressure Liquid; Depression; Dose-Response Relationship, Drug; Female; Humans; Japan; Male; Mianserin; Middle Aged; Stereoisomerism

1995

Other Studies

5 other study(ies) available for desmethylmianserin and Depression

ArticleYear
Mianserin in breast milk.
    British journal of clinical pharmacology, 1993, Volume: 36, Issue:2

    Topics: Adult; Depression; Female; Humans; Lactation; Mianserin; Milk, Human; Postpartum Period

1993
Steady-state plasma concentrations of mianserin and its major active metabolite, desmethylmianserin.
    Therapeutic drug monitoring, 1993, Volume: 15, Issue:2

    Topics: Adult; Age Factors; Aged; Chromatography, High Pressure Liquid; Depression; Female; Humans; Male; Mianserin; Middle Aged; Smoking

1993
Prediction of plasma concentrations of mianserin and desmethylmianserin at steady state from those after an initial dose of mianserin.
    Therapeutic drug monitoring, 1993, Volume: 15, Issue:2

    Topics: Adult; Aged; Animals; Depression; Female; Humans; Male; Mianserin; Middle Aged

1993
Effects of thioridazine, an inhibitor of CYP2D6, on the steady-state plasma concentrations of the enantiomers of mianserin and its active metabolite, desmethylmianserin, in depressed Japanese patients.
    Pharmacogenetics, 1997, Volume: 7, Issue:5

    Topics: Antidepressive Agents, Second-Generation; Cytochrome P-450 CYP2D6 Inhibitors; Depression; Enzyme Inhibitors; Female; Homozygote; Humans; Japan; Male; Mianserin; Stereoisomerism; Thioridazine

1997
Comparison of the effects of mianserin and its enantiomers and metabolites on a behavioral screen for antidepressant activity.
    Psychopharmacology, 1991, Volume: 105, Issue:4

    Topics: Analysis of Variance; Animals; Antidepressive Agents; Behavior, Animal; Conditioning, Operant; Depression; Male; Mianserin; Rats; Rats, Inbred Strains; Receptors, Serotonin; Stereoisomerism

1991