Page last updated: 2024-10-28

gyki 52466 and Depression

gyki 52466 has been researched along with Depression in 5 studies

GYKI 52466: an AMPA (non-NMDA) receptor antagonist; structure given in first source

Depression: Depressive states usually of moderate intensity in contrast with MAJOR DEPRESSIVE DISORDER present in neurotic and psychotic disorders.

Research Excerpts

ExcerptRelevanceReference
"Lentinan (LNT) is an immune regulator and its potential and mechanism for the treatment of mood disorder is of our interest."1.46Lentinan produces a robust antidepressant-like effect via enhancing the prefrontal Dectin-1/AMPA receptor signaling pathway. ( Bao, H; Du, J; Du, K; Gao, T; Hou, Y; Hu, W; Li, B; Nie, J; Ran, P; Shan, L; Sun, L; Xiao, C; Zheng, B; Zheng, S; Zhu, K; Zhu, Y, 2017)
" Both short- and long-term administration of lithium resulted in robust antidepressant-like effects in the mouse FST and TST."1.35Involvement of AMPA receptors in the antidepressant-like effects of lithium in the mouse tail suspension test and forced swim test. ( Chen, G; Dow, ER; Du, J; Gould, TD; Manji, HK; O'Donnell, KC, 2008)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's4 (80.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bao, H3
Ran, P3
Zhu, M1
Sun, L3
Li, B2
Hou, Y2
Nie, J2
Shan, L2
Li, H2
Zheng, S2
Xu, X1
Xiao, C3
Du, J4
Zhu, Y1
Hu, W2
Zhu, K2
Gao, T1
Du, K1
Zheng, B1
Farley, S1
Apazoglou, K1
Witkin, JM1
Giros, B1
Tzavara, ET1
Gould, TD1
O'Donnell, KC1
Dow, ER1
Chen, G1
Manji, HK1

Other Studies

5 other studies available for gyki 52466 and Depression

ArticleYear
The Prefrontal Dectin-1/AMPA Receptor Signaling Pathway Mediates The Robust and Prolonged Antidepressant Effect of Proteo-β-Glucan from Maitake.
    Scientific reports, 2016, 06-22, Volume: 6

    Topics: Animals; Antidepressive Agents; Benzodiazepines; beta-Glucans; Depression; Disease Models, Animal; G

2016
Lentinan produces a robust antidepressant-like effect via enhancing the prefrontal Dectin-1/AMPA receptor signaling pathway.
    Behavioural brain research, 2017, 01-15, Volume: 317

    Topics: Adjuvants, Immunologic; Animals; Antidepressive Agents, Tricyclic; Benzodiazepines; Depression; Dise

2017
Griflola frondosa (GF) produces significant antidepressant effects involving AMPA receptor activation in mice.
    Pharmaceutical biology, 2017, Volume: 55, Issue:1

    Topics: Animals; Antidepressive Agents; Behavior, Animal; Benzodiazepines; Depression; Disease Models, Anima

2017
Antidepressant-like effects of an AMPA receptor potentiator under a chronic mild stress paradigm.
    The international journal of neuropsychopharmacology, 2010, Volume: 13, Issue:9

    Topics: Animals; Antidepressive Agents; Behavior, Animal; Benzodiazepines; Chronic Disease; Depression; Depr

2010
Involvement of AMPA receptors in the antidepressant-like effects of lithium in the mouse tail suspension test and forced swim test.
    Neuropharmacology, 2008, Volume: 54, Issue:3

    Topics: Animals; Antidepressive Agents; Behavior, Animal; Benzodiazepines; Brain; Depression; Disease Models

2008