gyki 52466 has been researched along with Depression in 5 studies
GYKI 52466: an AMPA (non-NMDA) receptor antagonist; structure given in first source
Depression: Depressive states usually of moderate intensity in contrast with MAJOR DEPRESSIVE DISORDER present in neurotic and psychotic disorders.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Lentinan (LNT) is an immune regulator and its potential and mechanism for the treatment of mood disorder is of our interest." | 1.46 | Lentinan produces a robust antidepressant-like effect via enhancing the prefrontal Dectin-1/AMPA receptor signaling pathway. ( Bao, H; Du, J; Du, K; Gao, T; Hou, Y; Hu, W; Li, B; Nie, J; Ran, P; Shan, L; Sun, L; Xiao, C; Zheng, B; Zheng, S; Zhu, K; Zhu, Y, 2017) |
| " Both short- and long-term administration of lithium resulted in robust antidepressant-like effects in the mouse FST and TST." | 1.35 | Involvement of AMPA receptors in the antidepressant-like effects of lithium in the mouse tail suspension test and forced swim test. ( Chen, G; Dow, ER; Du, J; Gould, TD; Manji, HK; O'Donnell, KC, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 4 (80.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bao, H | 3 |
| Ran, P | 3 |
| Zhu, M | 1 |
| Sun, L | 3 |
| Li, B | 2 |
| Hou, Y | 2 |
| Nie, J | 2 |
| Shan, L | 2 |
| Li, H | 2 |
| Zheng, S | 2 |
| Xu, X | 1 |
| Xiao, C | 3 |
| Du, J | 4 |
| Zhu, Y | 1 |
| Hu, W | 2 |
| Zhu, K | 2 |
| Gao, T | 1 |
| Du, K | 1 |
| Zheng, B | 1 |
| Farley, S | 1 |
| Apazoglou, K | 1 |
| Witkin, JM | 1 |
| Giros, B | 1 |
| Tzavara, ET | 1 |
| Gould, TD | 1 |
| O'Donnell, KC | 1 |
| Dow, ER | 1 |
| Chen, G | 1 |
| Manji, HK | 1 |
5 other studies available for gyki 52466 and Depression
| Article | Year |
|---|---|
The Prefrontal Dectin-1/AMPA Receptor Signaling Pathway Mediates The Robust and Prolonged Antidepressant Effect of Proteo-β-Glucan from Maitake.
Topics: Animals; Antidepressive Agents; Benzodiazepines; beta-Glucans; Depression; Disease Models, Animal; G | 2016 |
Lentinan produces a robust antidepressant-like effect via enhancing the prefrontal Dectin-1/AMPA receptor signaling pathway.
Topics: Adjuvants, Immunologic; Animals; Antidepressive Agents, Tricyclic; Benzodiazepines; Depression; Dise | 2017 |
Griflola frondosa (GF) produces significant antidepressant effects involving AMPA receptor activation in mice.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Benzodiazepines; Depression; Disease Models, Anima | 2017 |
Antidepressant-like effects of an AMPA receptor potentiator under a chronic mild stress paradigm.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Benzodiazepines; Chronic Disease; Depression; Depr | 2010 |
Involvement of AMPA receptors in the antidepressant-like effects of lithium in the mouse tail suspension test and forced swim test.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Benzodiazepines; Brain; Depression; Disease Models | 2008 |