phenytoin has been researched along with Depression in 35 studies
Depression: Depressive states usually of moderate intensity in contrast with MAJOR DEPRESSIVE DISORDER present in neurotic and psychotic disorders.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Epilepsy-associated comorbid depression was evaluated by tail suspension test, sucrose preference test, and plasma corticosterone levels, whereas epilepsy-associated memory deficit condition was assessed by step-through paradigm, Morris water maze, and nitrite levels." | 3.96 | Exploring the ameliorative role of α7 neuronal nicotinic acetylcholine receptor modulation in epilepsy and associated comorbidities in post-PTZ-kindled mice. ( Goel, RK; Kaur, S; Sharma, NK, 2020) |
| " Both were found to have toxic levels of Dilantin." | 1.28 | Dilantin toxicity and vegetative depression: a report of two cases. ( Garrison, SJ; Henson, HK, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 28 (80.00) | 18.7374 |
| 1990's | 5 (14.29) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (2.86) | 24.3611 |
| 2020's | 1 (2.86) | 2.80 |
| Authors | Studies |
|---|---|
| Sharma, NK | 1 |
| Kaur, S | 1 |
| Goel, RK | 2 |
| Singh, P | 1 |
| Singh, D | 1 |
| HUSBY, J | 1 |
| PRESTON, DN | 1 |
| ATACK, EA | 1 |
| Snyder, S | 1 |
| Ritson, B | 1 |
| Sun, M | 1 |
| Levkovitch, Y | 1 |
| Abramovitch, Y | 1 |
| Nizan, I | 1 |
| Cohen, O | 1 |
| River, Y | 1 |
| Abramsky, O | 1 |
| Freed, ED | 1 |
| Green, AR | 1 |
| Grahame-Smith, DG | 1 |
| Perucca, E | 1 |
| Richens, A | 1 |
| Warneke, LB | 1 |
| Altshuler, LL | 1 |
| Devinsky, O | 1 |
| Post, RM | 1 |
| Theodore, W | 1 |
| Kim, C | 1 |
| Garrison, SJ | 1 |
| Henson, HK | 1 |
| Rosalki, SB | 1 |
| Tarlow, D | 1 |
| Rau, D | 1 |
| Golochevskaia, VS | 1 |
| Marsden, CD | 1 |
| Reynolds, EH | 1 |
| Parsons, V | 1 |
| Harris, R | 1 |
| Duchen, L | 1 |
| Kristianson, P | 1 |
| Taylor, CR | 1 |
| Rose, LI | 1 |
| Williams, GH | 1 |
| Jagger, PI | 1 |
| Lauler, DP | 1 |
| Thorn, GW | 1 |
| Hogg, PS | 1 |
| Uhlenhuth, EH | 1 |
| Stephens, JH | 1 |
| Dim, BH | 1 |
| Covi, L | 1 |
| Overall, JE | 1 |
| Brown, D | 1 |
| Williams, JD | 1 |
| Neill, LT | 1 |
| Green, RS | 1 |
| Rau, JH | 1 |
| Resnich, O | 1 |
| Malitz, S | 1 |
| Kanzler, M | 1 |
| Moss-Herjanic, B | 1 |
| Madden, JS | 1 |
| Jones, D | 1 |
| Frisch, EP | 2 |
| Glatt, MM | 1 |
| George, HR | 1 |
| Nissen, G | 1 |
| Jonas, AD | 1 |
| Turner, WJ | 1 |
| Monroe, RR | 1 |
| Kramer, MD | 1 |
| Goulding, R | 1 |
| Wise, S | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Monitoring of Seizures, EEG and Serum Antiepileptic Drug Concentrations in Patients With Uncontrolled Epilepsy[NCT00001149] | 900 participants | Observational | 1975-11-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for phenytoin and Depression
| Article | Year |
|---|---|
The interaction of psychopharmacology and psychoanalysis in the borderline patient.
Topics: Affect; Anger; Antipsychotic Agents; Borderline Personality Disorder; Chlorpromazine; Clinical Trial | 1980 |
Effects of drugs on the processes regulating the functional activity of brain 5-hydroxytryptamine.
Topics: Animals; Brain; Clomipramine; Depression; Dopamine; Humans; Hydroxyindoleacetic Acid; Lithium; Model | 1976 |
[Side effects of anti-arrhythmic agents].
Topics: 1-Propanol; Adrenal Cortex Hormones; Agranulocytosis; Anorexia Nervosa; Anti-Arrhythmia Agents; Anti | 1971 |
7 trials available for phenytoin and Depression
| Article | Year |
|---|---|
The interaction of psychopharmacology and psychoanalysis in the borderline patient.
Topics: Affect; Anger; Antipsychotic Agents; Borderline Personality Disorder; Chlorpromazine; Clinical Trial | 1980 |
Double-blind crossover study of diphenylhydantoin in angina pectoris.
Topics: Administration, Oral; Angina Pectoris; Clinical Trials as Topic; Depression; Electrocardiography; Ex | 1974 |
Diphenylhydantoin and phenobarbital in the relief of psychoneurotic symptoms. A controlled comparison.
Topics: Adolescent; Adult; Aged; Anxiety Disorders; Clinical Trials as Topic; Conversion Disorder; Depressio | 1972 |
Drug treatment of anxiety and depression in detoxified alcoholic patients.
Topics: Alcoholism; Amitriptyline; Analysis of Variance; Anxiety; Ascorbic Acid; Chlordiazepoxide; Depressio | 1973 |
The psychoactive properties of diphenylhydantoin: experiences with prisoners and juvenile delinquents.
Topics: Adolescent; Adult; Affect; Child; Child Behavior Disorders; Clinical Trials as Topic; Criminal Psych | 1967 |
Are antidepressants better than placebo?
Topics: Adjustment Disorders; Adult; Aged; Amitriptyline; Antidepressive Agents; Anxiety; Clinical Trials as | 1971 |
Evaluation of chlormethiazole in treatment for alcohol withdrawal syndrome. Results of a controlled trial.
Topics: Alcoholism; Chlormethiazole; Clinical Trials as Topic; Depression; Female; Humans; Hypertension; Hyp | 1966 |
26 other studies available for phenytoin and Depression
| Article | Year |
|---|---|
Exploring the ameliorative role of α7 neuronal nicotinic acetylcholine receptor modulation in epilepsy and associated comorbidities in post-PTZ-kindled mice.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Anticonvulsants; Corticosterone; Depression; Dose- | 2020 |
Ficus religiosa L. figs--a potential herbal adjuvant to phenytoin for improved management of epilepsy and associated behavioral comorbidities.
Topics: Animals; Anticonvulsants; Antioxidants; Behavior, Animal; Cognition Disorders; Comorbidity; Depressi | 2014 |
DELAYED TOXICITY AND SERUM CONCENTRATIONS OF PHENYTOIN.
Topics: Blood Chemical Analysis; Consciousness; Depression; Depressive Disorder; Epilepsy; Humans; Neurologi | 1963 |
TEMPORAL LOBE EPILEPSY: A CLINICAL STUDY OF 47 CASES.
Topics: Adolescent; Biomedical Research; Birth Injuries; Depression; Depressive Disorder; Diagnosis, Differe | 1964 |
ABC of alcohol. Help: drugs.
Topics: Alcoholism; Depression; Ethanol; Humans; Phenytoin; Tranquilizing Agents; Vitamins | 1982 |
Book touts Dilantin for depression.
Topics: Depression; Humans; Phenytoin | 1982 |
[Dilantin toxicity as a possible cause of major depression].
Topics: Aged; Depression; Female; Folic Acid; Humans; Phenytoin | 1993 |
Seizures induced by frustration and despair due to unresolved moral and political issues: a rare case of reflex epilepsy.
Topics: Aged; Anticonvulsants; Depression; Frustration; Humans; Male; Morals; Phenytoin; Politics; Seizures; | 1999 |
The drug management of acute behavioural disturbances.
Topics: Acting Out; Acute Disease; Adrenergic beta-Antagonists; Aged; Antidepressive Agents, Tricyclic; Anti | 1975 |
Interaction between phenytoin and imipramine.
Topics: Adult; Depression; Drug Interactions; Epilepsy; Humans; Imipramine; Phenytoin; Time Factors | 1977 |
A case of temporal lobe epilepsy with an orgasmic component.
Topics: Adult; Anxiety; Depression; Dominance, Cerebral; Epilepsy, Temporal Lobe; Functional Laterality; Hal | 1976 |
Depression, anxiety, and temporal lobe epilepsy. Laterality of focus and symptoms.
Topics: Adult; Analysis of Variance; Anxiety; Carbamazepine; Depression; Epilepsy, Temporal Lobe; Female; Fu | 1990 |
Dilantin toxicity and depression.
Topics: Cimetidine; Depression; Drug Administration Schedule; Drug Interactions; Humans; Phenytoin | 1990 |
Dilantin toxicity and vegetative depression: a report of two cases.
Topics: Depression; Drug Administration Schedule; Female; Humans; Middle Aged; Phenytoin | 1990 |
Plasma gamma-glutamyl transpeptidase elevation in patients receiving enzyme-inducing drugs.
Topics: Acyltransferases; Depression; Drug Synergism; Enzyme Induction; Epilepsy; Ethanol; Glutamates; Human | 1971 |
Myopathy associated with anticonvulsant osteomalacia.
Topics: Adult; Anticonvulsants; Back Pain; Depression; Electroencephalography; Electromyography; Ergocalcife | 1973 |
A comparison between the personality changes in certain forms of psychomotor and grand-mal epilepsy.
Topics: Adult; Depression; Electroencephalography; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Humans; | 1974 |
The paradoxical dexamethasone reponse phenomenon.
Topics: 17-Hydroxycorticosteroids; Adrenocortical Hyperfunction; Adrenocorticotropic Hormone; Adult; Depress | 1969 |
Three cases of 'restless legs' or 'Ekbom's syndrome' as seen in general practice.
Topics: Adult; Aged; Anxiety; Depression; Female; Humans; Leg; Male; Middle Aged; MMPI; Movement Disorders; | 1972 |
Treatment of compulsive eating disturbances with anticonvulsant medication.
Topics: Adolescent; Adult; Amphetamine; Anorexia Nervosa; Body Image; Body Weight; Compulsive Behavior; Depr | 1974 |
Prolonged unconsciousness following electroconvulsive therapy.
Topics: Adult; Aged; Coma; Craniocerebral Trauma; Depression; Electroconvulsive Therapy; Epilepsies, Partial | 1967 |
Chlormethiazole and trifluoperazine in alcohol withdrawal.
Topics: Alcoholism; Chlormethiazole; Coma; Depression; Feeding and Eating Disorders; Female; Headache; Human | 1969 |
[Depressive syndromes in childhood and adolescence. Symptomatology, etiology and prognosis].
Topics: Adolescent; Age Factors; Child; Child Development; Child Psychiatry; Child, Hospitalized; Child, Pre | 1971 |
The diagnostic and therapeutic use of diphenylhydantoin in the subictal state and non-epileptic dysphoria.
Topics: Adjustment Disorders; Antisocial Personality Disorder; Anxiety Disorders; Depression; Emotions; Epil | 1967 |
The usefulness of diphenylhydantoin in treatment of non-epileptic emotional disorders.
Topics: Age Factors; Cell Membrane; Depression; Electroencephalography; Emotions; Epilepsy; Fear; Female; He | 1967 |
EFG activation of patients receiving phenothiazines and chlordiazepoxide.
Topics: Adult; Anxiety; Cerebral Cortex; Chloralose; Chlordiazepoxide; Chlorpromazine; Depression; Electroen | 1965 |