Page last updated: 2024-10-27

vanoxerine and Depression

vanoxerine has been researched along with Depression in 1 studies

vanoxerine: structure given in first source
vanoxerine : An N-alkylpiperazine that consists of piperazine bearing 2-bis(4-fluorophenyl)methoxy]ethyl and 3-phenylpropyl groups at positions 1 and 4 respectively. Potent, competitive inhibitor of dopamine uptake (Ki = 1 nM for inhibition of striatal dopamine uptake). Has > 100-fold lower affinity for the noradrenalin and 5-HT uptake carriers. Also a potent sigma ligand (IC50 = 48 nM). Centrally active following systemic administration.

Depression: Depressive states usually of moderate intensity in contrast with MAJOR DEPRESSIVE DISORDER present in neurotic and psychotic disorders.

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
van Enkhuizen, J1
Milienne-Petiot, M1
Geyer, MA1
Young, JW1

Other Studies

1 other study available for vanoxerine and Depression

ArticleYear
Modeling bipolar disorder in mice by increasing acetylcholine or dopamine: chronic lithium treats most, but not all features.
    Psychopharmacology, 2015, Volume: 232, Issue:18

    Topics: Acetylcholine; Animals; Antimanic Agents; Behavior, Animal; Bipolar Disorder; Cholinesterase Inhibit

2015