cimetidine has been researched along with Depression in 13 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
Depression: Depressive states usually of moderate intensity in contrast with MAJOR DEPRESSIVE DISORDER present in neurotic and psychotic disorders.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Twenty-one patients with endoscopically proven active duodenal ulcers were studied in a double-blind randomized trial comparing doxepin hydrochloride (50 mg during the first week, and 100 mg thereafter, at bedtime) and cimetidine (1,200 mg/day in four divided doses)." | 9.05 | Doxepin and cimetidine in the treatment of duodenal ulcer: a double-blind comparative study. ( Shah, BK; Shrivastava, RK; Siegal, H, 1985) |
| "The role of the central histaminergic system in depression was studied by using swimming despair test in mice - a behavioural model of depression." | 7.67 | Role of central histaminergic mechanism in behavioural depression (swimming despair) in mice. ( Dhawan, KN; Gulati, A; Gupta, GP; Nath, C, 1988) |
| "Twenty-one patients with endoscopically proven active duodenal ulcers were studied in a double-blind randomized trial comparing doxepin hydrochloride (50 mg during the first week, and 100 mg thereafter, at bedtime) and cimetidine (1,200 mg/day in four divided doses)." | 5.05 | Doxepin and cimetidine in the treatment of duodenal ulcer: a double-blind comparative study. ( Shah, BK; Shrivastava, RK; Siegal, H, 1985) |
| "The role of the central histaminergic system in depression was studied by using swimming despair test in mice - a behavioural model of depression." | 3.67 | Role of central histaminergic mechanism in behavioural depression (swimming despair) in mice. ( Dhawan, KN; Gulati, A; Gupta, GP; Nath, C, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (76.92) | 18.7374 |
| 1990's | 1 (7.69) | 18.2507 |
| 2000's | 1 (7.69) | 29.6817 |
| 2010's | 1 (7.69) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wu, DY | 1 |
| Guo, M | 1 |
| Gao, YS | 1 |
| Kang, YH | 1 |
| Guo, JC | 1 |
| Jiang, XL | 1 |
| Chen, F | 1 |
| Liu, T | 1 |
| Li, M | 1 |
| Tincello, DG | 1 |
| Walker, AC | 1 |
| Slaby, AE | 1 |
| Hails, KC | 1 |
| Jefferson, JW | 1 |
| Petite, JP | 1 |
| Bloch, F | 1 |
| Johnson, J | 1 |
| Bailey, S | 1 |
| Kim, C | 1 |
| Antell, LA | 1 |
| Murabito, AS | 1 |
| Karlstadt, RG | 1 |
| Gangat, AE | 1 |
| Simpson, MA | 1 |
| Naidoo, LR | 1 |
| Nath, C | 1 |
| Gulati, A | 1 |
| Dhawan, KN | 1 |
| Gupta, GP | 1 |
| Shrivastava, RK | 1 |
| Shah, BK | 1 |
| Siegal, H | 1 |
| Larson, EB | 1 |
| Reifler, BV | 1 |
| Sumi, SM | 1 |
| Canfield, CG | 1 |
| Chinn, NM | 1 |
2 reviews available for cimetidine and Depression
| Article | Year |
|---|---|
Emergency psychiatry: an update.
Topics: Affective Symptoms; Cimetidine; Depression; Diagnosis, Differential; Digitalis Glycosides; Emergency | 1981 |
Medication as a potential cause of depression.
Topics: Antihypertensive Agents; Antipsychotic Agents; Cardiovascular Agents; Cimetidine; Contraceptives, Or | 1986 |
2 trials available for cimetidine and Depression
| Article | Year |
|---|---|
Clinical effects of psychological intervention and drug therapy against peptic ulcer.
Topics: Adult; Anti-Ulcer Agents; Anxiety; China; Cimetidine; Cognitive Behavioral Therapy; Combined Modalit | 2012 |
Doxepin and cimetidine in the treatment of duodenal ulcer: a double-blind comparative study.
Topics: Adult; Aged; Anxiety; Cimetidine; Clinical Trials as Topic; Depression; Double-Blind Method; Doxepin | 1985 |
9 other studies available for cimetidine and Depression
| Article | Year |
|---|---|
Interstitial cystitis in the UK: results of a questionnaire survey of members of the Interstitial Cystitis Support Group.
Topics: Anticonvulsants; Cimetidine; Cystitis, Interstitial; Depression; Dimethyl Sulfoxide; Female; Histami | 2005 |
Neuropsychiatric side effects of cimetidine.
Topics: Adult; Aged; Cimetidine; Delirium; Depression; Duodenal Ulcer; Gastric Acid; Gastritis; Gastrointest | 1982 |
Central nervous system toxicity of cimetidine: a case of depression.
Topics: Aged; Central Nervous System; Cimetidine; Depression; Guanidines; Humans; Male; Peptic Ulcer | 1979 |
[Depressive syndrome during cimetidine treatment].
Topics: Cimetidine; Confusion; Depression; Guanidines; Humans; Male; Middle Aged; Psychoses, Substance-Induc | 1979 |
Cimetidine and psychiatric complications.
Topics: Adult; Anxiety Disorders; Cimetidine; Depression; Duodenal Ulcer; Female; Guanidines; Humans | 1979 |
Dilantin toxicity and depression.
Topics: Cimetidine; Depression; Drug Administration Schedule; Drug Interactions; Humans; Phenytoin | 1990 |
Depression not associated with cimetidine.
Topics: Aged; Aged, 80 and over; Chronic Disease; Cimetidine; Depression; Humans; Product Surveillance, Post | 1989 |
Role of central histaminergic mechanism in behavioural depression (swimming despair) in mice.
Topics: Animals; Atropine; Central Nervous System; Cimetidine; Depression; Desipramine; Disease Models, Anim | 1988 |
Diagnostic evaluation of 200 elderly outpatients with suspected dementia.
Topics: Aged; Alzheimer Disease; Cimetidine; Cognition Disorders; Dementia; Depression; Follow-Up Studies; H | 1985 |