1,2-dimethylhydrazine has been researched along with Depression in 2 studies
1,2-Dimethylhydrazine: A DNA alkylating agent that has been shown to be a potent carcinogen and is widely used to induce colon tumors in experimental animals.
1,2-dimethylhydrazine : A member of the class of hydrazines that is hydrazine in which one of the hydrogens attached to each nitrogen is replaced by a methyl group. A powerful DNA alkylating agent and carcinogen, it is used to induce colon cancer in laboratory rats and mice.
Depression: Depressive states usually of moderate intensity in contrast with MAJOR DEPRESSIVE DISORDER present in neurotic and psychotic disorders.
| Excerpt | Relevance | Reference |
|---|---|---|
| "What is the central question of this study? What are the alleviative effects of the combination of exercise training and quercetin supplementation on colorectal cancer-related depression in rats with 1,2-dimethylhydrazine-induced colorectal cancer and what is the corresponding signalling pathway? What is the main finding and its importance? We showed that the combination of exercise training and quercetin supplementation resulted in a significant decrease in tumour incidence and improvement in depressive-like behaviours through modulation of the BDNF/TrKβ/β-catenin axis in the prefrontal cortex." | 7.96 | Combination of quercetin and exercise training attenuates depression in rats with 1,2-dimethylhydrazine-induced colorectal cancer: Possible involvement of inflammation and BDNF signalling. ( Babaei, G; Darband, SG; Ghaderi-Pakdel, F; Kaviani, M; Majidinia, M; Mihanfar, A; Mobaraki, K; Sadighparvar, S; Yousefi, B, 2020) |
| "What is the central question of this study? What are the alleviative effects of the combination of exercise training and quercetin supplementation on colorectal cancer-related depression in rats with 1,2-dimethylhydrazine-induced colorectal cancer and what is the corresponding signalling pathway? What is the main finding and its importance? We showed that the combination of exercise training and quercetin supplementation resulted in a significant decrease in tumour incidence and improvement in depressive-like behaviours through modulation of the BDNF/TrKβ/β-catenin axis in the prefrontal cortex." | 3.96 | Combination of quercetin and exercise training attenuates depression in rats with 1,2-dimethylhydrazine-induced colorectal cancer: Possible involvement of inflammation and BDNF signalling. ( Babaei, G; Darband, SG; Ghaderi-Pakdel, F; Kaviani, M; Majidinia, M; Mihanfar, A; Mobaraki, K; Sadighparvar, S; Yousefi, B, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yang, P | 1 |
| Hernandez, BS | 1 |
| Plastino, KA | 1 |
| Sadighparvar, S | 1 |
| Darband, SG | 1 |
| Yousefi, B | 1 |
| Kaviani, M | 1 |
| Ghaderi-Pakdel, F | 1 |
| Mihanfar, A | 1 |
| Babaei, G | 1 |
| Mobaraki, K | 1 |
| Majidinia, M | 1 |
2 other studies available for 1,2-dimethylhydrazine and Depression
| Article | Year |
|---|---|
Social determinants of mental health and adolescent anxiety and depression: Findings from the 2018 to 2019 National Survey of Children's Health.
Topics: 1,2-Dimethylhydrazine; Adolescent; Anxiety; Child; Child Health; Depression; Humans; Mental Health; | 2023 |
Combination of quercetin and exercise training attenuates depression in rats with 1,2-dimethylhydrazine-induced colorectal cancer: Possible involvement of inflammation and BDNF signalling.
Topics: 1,2-Dimethylhydrazine; Animals; beta Catenin; Brain-Derived Neurotrophic Factor; Colorectal Neoplasm | 2020 |