mitotane has been researched along with Depression in 2 studies
Mitotane: A derivative of the insecticide DICHLORODIPHENYLDICHLOROETHANE that specifically inhibits cells of the adrenal cortex and their production of hormones. It is used to treat adrenocortical tumors and causes CNS damage, but no bone marrow depression.
Depression: Depressive states usually of moderate intensity in contrast with MAJOR DEPRESSIVE DISORDER present in neurotic and psychotic disorders.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treatment with metyrapone or o,p'-DDD can always induce a clinical remission but not a cure, and neurotransmitter therapy may be effective in a minority of cases." | 2.37 | Cushing's syndrome. ( Besser, GM; Howlett, TA; Rees, LH, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Howlett, TA | 1 |
| Rees, LH | 1 |
| Besser, GM | 1 |
| Starkman, MN | 1 |
| Schteingart, DE | 1 |
| Schork, MA | 1 |
1 review available for mitotane and Depression
| Article | Year |
|---|---|
Cushing's syndrome.
Topics: Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Adrenalectomy; Adrenocorticotropic Hormone; Alcoho | 1985 |
1 other study available for mitotane and Depression
| Article | Year |
|---|---|
Cushing's syndrome after treatment: changes in cortisol and ACTH levels, and amelioration of the depressive syndrome.
Topics: Adrenocorticotropic Hormone; Adult; Cushing Syndrome; Depression; Female; Humans; Hydrocortisone; Ma | 1986 |