imipramine has been researched along with Depression in 1385 studies
Imipramine: The prototypical tricyclic antidepressant. It has been used in major depression, dysthymia, bipolar depression, attention-deficit disorders, agoraphobia, and panic disorders. It has less sedative effect than some other members of this therapeutic group.
imipramine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine substituted by a 3-(dimethylamino)propyl group at the nitrogen atom.
Depression: Depressive states usually of moderate intensity in contrast with MAJOR DEPRESSIVE DISORDER present in neurotic and psychotic disorders.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Scopus, ISI, Embase, PubMed, Cochrane Library, Google Scholar, and two trial registries were searched for randomized controlled trials on the effectiveness of topiramate, phenobarbital, and other ten barbiturates in depression." | 9.22 | Topiramate and other kainate receptor antagonists for depression: A systematic review of randomized controlled trials. ( Shamabadi, A, 2022) |
| "Saffron at this dose was found to be effective similar to imipramine in the treatment of mild to moderate depression (F = 2." | 9.11 | Comparison of Crocus sativus L. and imipramine in the treatment of mild to moderate depression: a pilot double-blind randomized trial [ISRCTN45683816]. ( Afkham, K; Akhondzadeh, S; Fallah-Pour, H; Jamshidi, AH; Khalighi-Cigaroudi, F, 2004) |
| "To compare the antidepressant efficacy and tolerability of sertraline (50 mg/day) and imipramine (150 mg/day) in the first 6 weeks of the treatment of major depression in the elderly." | 9.09 | Antidepressant efficacy of sertraline and imipramine for the treatment of major depression in elderly outpatients. ( Ferreira, RC; Forlenza, OV; Hirata, ES; Stoppe Júnior, A, 2000) |
| "To compare the efficacy and tolerability of Hypericum perforatum (St John's wort extract) with imipramine in patients with mild to moderate depression." | 9.09 | Comparison of St John's wort and imipramine for treating depression: randomised controlled trial. ( Woelk, H, 2000) |
| " In a multicentre, 6 months, placebo-controlled trial, amisulpride (50 mg/daily) was compared to imipramine (100 mg/daily) in the treatment of patients with DSM-III-R criteria for primary dysthymia, dysthymia with major depression or major depression in partial remission." | 9.08 | Amisulpride versus imipramine and placebo in dysthymia and major depression. Amisulpride Study Group. ( Boyer, P; Lecrubier, Y; Rein, W; Turjanski, S, 1997) |
| "Fluvoxamine, a selective serotonin reuptake inhibitor, was investigated in a 6-week double-blind study among severely ill inpatients with DSM-III major depression." | 9.06 | A placebo-controlled inpatient comparison of fluvoxamine maleate and imipramine in major depression. ( Boyer, WF; Feighner, JP; Hendrickson, GG; Meredith, CH, 1989) |
| "Thirty-seven patients participating in a controlled treatment study with imipramine were classified as high or low depressed simultaneously on two depression measures." | 9.06 | Initial depression and response to imipramine in agoraphobia. ( Mavissakalian, M, 1987) |
| " Twenty-eight inpatients with a diagnosis of endogenous depression received either trazodone, imipramine, or placebo." | 9.04 | Trazodone, a new antidepressant: efficacy and safety in endogenous depression. ( Kellams, JJ; Klapper, MH; Small, JG, 1979) |
| "Thirty-eight in-patients with endogenous- and 20 in-patients with non-endogenous depression, took part in a multi-centre 3-week double-blind trial where patients were randomly allocated to treatment with either 6 g L-tryptophan or 150 mg imipramine daily." | 9.04 | Symptom reduction in depression after treatment with L-tryptophan or imipramine. Item analysis of Hamilton rating scale for depression. ( Ahlfors, UG; Dencker, SJ; Fruensgaard, K; Hanstén, S; Jensen, K; Lindberg, D; Ose, E; Pihkanen, TA, 1979) |
| "The effect of lithium carbonate therapy on patients with depression is still unconfirmed." | 9.04 | Double-blind comparison of lithium carbonate and imipramine in treatment of depression. ( Ishino, H; Otsuki, S; Watanabe, S, 1975) |
| "The purpose of this study is to describe the clinical and light microscopic findings in 4 patients with imipramine-induced hyperpigmentation and to better understand its origin." | 8.80 | Imipramine-induced hyperpigmentation: four cases and a review of the literature. ( Bhawan, J; Cohen, LM; McCalmont, TH; Ming, ME; Stefanato, CM, 1999) |
| "To examine the possible role of impramine and agmatine through a mTOR signal pathway on rat ovary after maternal separation stress-induced depression." | 8.31 | The effect of maternal separation stress-induced depression on ovarian reserve in Sprague Dawley Rats: The possible role of imipramine and agmatine through a mTOR signal pathway. ( Arıcıoğlu, F; Önel, T; Yaba, A; Yıldırım, E; Zortul, H, 2023) |
| "Considering that serotoninergic agents attenuate symptoms of anxiety and are used to treat depression, we investigated whether subchronic treatment with imipramine, a serotonin/noradrenaline reuptake inhibitor, would prevent the anxiogenic-like behaviour induced by acute and/or chronic ethanol withdrawal." | 8.02 | Imipramine attenuates anxiety- and depressive-like effects of acute and prolonged ethanol-abstinence in male rats by modulating SERT and GR expression in the dorsal hippocampus. ( Anselmo-Franci, JA; Campos-Cardoso, R; Carolino, ROG; Padovan, CM; Silva, CPB; Tirapelli, CR, 2021) |
| " Imipramine treatment was able to reverse depressive- and anxiety-like behaviors." | 7.91 | Imipramine treatment reverses depressive- and anxiety-like behaviors, normalize adrenocorticotropic hormone, and reduces interleukin-1β in the brain of rats subjected to experimental periapical lesion. ( Barichello, T; Ceretta, RA; Dal-Pizzol, F; Dominguini, D; Generoso, JS; Michels, M; Netto, S; Réus, GZ; Simões, LR; Valim, RF; Valvassori, SS, 2019) |
| "Depression is associated with dysregulation of methyl group metabolism such as low S-adenosylmethionine (SAM)." | 7.91 | Behavioral and metabolic effects of S-adenosylmethionine and imipramine in the Flinders Sensitive Line rat model of depression. ( Geisel, J; Happ, DF; Mikkelsen, PF; Obeid, R; Tillmann, S; Wegener, G, 2019) |
| "The aim of the present study was to investigate the effects of ketamine, imipramine, and ketamine plus imipramine on chronic depression-like behaviors of Wistar Kyoto (WKY) rats and underlying mechanism." | 7.83 | [Effects of ketamine, imipramine, and their combination on depression-like behaviors in Wistar Kyoto rats]. ( Jin, XJ; Li, QQ; Peng, LC; Ye, K, 2016) |
| "A new (aryloxyalkyl)adenine derivative Adeprophen (9-[2-(4-isopropylphenoxy)ethyl]adenine, VMA-99-82) has a strong antidepressant effect on the model of reserpine-induced depression in rats (single dose 4 mg/kg, intraperitoneally)." | 7.83 | Comparison of the Efficiency of Adeprophen and Antidepressants of Various Groups on the Model of Reserpine-Induced Depression in Rats. ( Bagmetova, VV; Chernysheva, YV; Ozerov, AA; Tyurenkov, IN, 2016) |
| "In order to relieve anxiety and depression accompanying stress, physicians resort to tricyclic antidepressants, such as imipramine." | 7.83 | Antidepressant imipramine diminishes stress-induced inflammation in the periphery and central nervous system and related anxiety- and depressive- like behaviors. ( Ramirez, K; Sheridan, JF, 2016) |
| " We tested if blockade or activation of serotonin (5-HT)(2) receptors affected the time of immobility (as an indirect measure of depression-like behavior) in naïve animals and in those withdrawn from chronic nicotine in the forced swim test (FST)." | 7.76 | Effects of serotonin (5-HT)2 receptor ligands on depression-like behavior during nicotine withdrawal. ( Filip, M; McCreary, AC; Wydra, K; Zaniewska, M, 2010) |
| "To evaluate the antidepressant effect of imipramine on depressive symptoms observed in sepsis survivors rats." | 7.74 | Imipramine reverses the depressive symptoms in sepsis survivor rats. ( Antunes, MM; Comim, CM; Constantino, LS; Dal-Pizzol, F; Izquierdo, I; Machado, RA; Quevedo, J; Tuon, L, 2007) |
| "Cholecystokinin (CCK) involvement in depression-like disorders is poorly documented." | 7.74 | Repeated social defeat-induced depression-like behavioral and biological alterations in rats: involvement of cholecystokinin. ( Becker, C; Benoliel, JJ; Blugeot, A; Hamon, M; Rivat, C; Zeau, B, 2008) |
| "The use of carbamazepine has been reported to be an effective treatment for severe depression." | 7.74 | Chronic coadministration of carbamazepine together with imipramine produces antidepressant-like effects in an ACTH-induced animal model of treatment-resistant depression: involvement of 5-HT(2A) receptors? ( Akiyama, K; Araki, H; Gomita, Y; Kawasaki, H; Kitagawa, K; Kitamura, Y; Sendo, T; Shibata, K; Suemaru, K, 2008) |
| "A dysregulated hypothalamic-pituitary-adrenal axis (HPA) has been implicated in major depressive disorder and most commonly used animal models of depression have been shown to elevate circulating levels of plasma corticosterone." | 7.74 | Chronic low dose corticosterone exposure decreased hippocampal cell proliferation, volume and induced anxiety and depression like behaviours in mice. ( Hutson, PH; Murray, F; Smith, DW, 2008) |
| "Imipramine as the positive contrast medicine, effects of MC on the depression behavior of mice were observed by forced swimming test and reserpine antagonist test." | 7.72 | [Effect of madecassoside on depression behavior of mice and activities of MAO in different brain regions of rats]. ( Chen, Y; Han, T; Liu, MR; Qin, LP; Rui, YC; Zheng, HC, 2004) |
| "Two women, aged 65 and 43 years, who were suffering from tricyclic-resistant depressions, developed a (hypo)manic state after a few days of lithium addition." | 7.71 | [Manic state during the addition of lithium in the case of depression resistant to imipramine]. ( Beck-Lie A Fat, JR; Birkenhäger, TK; Renes, JW, 2002) |
| "The purpose of this study was to examine the metabolites of lofepramine (LOF), namely desipramine (DMI), desmethyl desipramine (DDMI) and desmethyl lofepramine (DML) in the forced swim and olfactory bulbectomized (OB) rat models of depression." | 7.70 | An investigation of the antidepressant properties of lofepramine and its desmethylated metabolites in the forced swim and olfactory bulbectomized rat models of depression. ( Kelly, JP; Leonard, BE, 1999) |
| "A chronic mild stress (CMS) model of depression was used to study an antidepressant-like activity of alnespirone (S 20499), a selective agonist of 5-HT1A receptors." | 7.70 | Alnespirone (S 20499), an agonist of 5-HT1A receptors, and imipramine have similar activity in a chronic mild stress model of depression. ( Muñoz, C; Papp, M, 1999) |
| " In addition, hypericum extracts, as well as standard antidepressants such as the tricyclic, impramine, and the selective serotonin reuptake inhibitor, fluoxetine, have been reported to be of therapeutic benefit in the treatment of alcoholism, as these compounds may reduce alcohol craving and/or intake in particular subgroups of patients." | 7.70 | Comparison of hypericum extracts with imipramine and fluoxetine in animal models of depression and alcoholism. ( de Beun, R; De Vry, J; Jentzsch, KR; Maurel, S; Schreiber, R, 1999) |
| "The selective sigma2 (sigma2) ligand Lu 28-179, or 1'-[4[1-(4-fluorophenyl)-1H-indol-3-yl]-l-butyl]spiro[isobenzofuran++ +-1(3H),4'-piperidine], was studied in the chronic mild stress (CMS) model of depression." | 7.70 | The selective sigma2 ligand Lu 28-179 has an antidepressant-like profile in the rat chronic mild stress model of depression. ( Papp, M; Sánchez, C, 2000) |
| " We corroborated some previous findings that CMS, which had been used as an animal model of depression, decreased the consumption of a 1% sucrose solution and that that effect was reversed by chronic administration of imipramine." | 7.69 | The effect of chronic treatment with imipramine on the responsiveness of hippocampal CA1 neurons to phenylephrine and serotonin in a chronic mild stress model of depression. ( Bijak, M; Papp, M, 1995) |
| " We present a case of massive imipramine overdose complicated by ventricular fibrillation and a prolonged period of cardiovascular collapse." | 7.69 | Tricyclic poisoning--successful management of ventricular fibrillation following massive overdose of imipramine. ( Alahakoon, TI; Bentley, SC; Sandeman, DJ, 1997) |
| "The response to treatment with imipramine or clonazepam was evaluated in patients with panic disorder." | 7.68 | [Treatment of patients with panic disorder and an elevated urinary excretion of MHPG using imipramine or clonazepam]. ( Carreira, I; Casique, M; Lima, L; Morales, M; Silva, C, 1992) |
| "Platelet [3H]imipramine binding was measured in 40 migrainous (7 classical and 33 common) and 17 tension headache patients and in 28 normal controls." | 7.68 | Platelet [3H]imipramine binding in migraine and tension headache in relation to depression. ( Davies, PT; Fernandez, M; Glover, V; Jarman, J; Rose, FC; Sandler, M; Steiner, TJ, 1991) |
| " Imipramine and mianserine potentiated amphetamine-induced anorexia both after acute administration or after prolonged previous treatment with each drug." | 7.68 | Lack of tolerance to imipramine or mianserine in two animal models of depression. ( Barros, HM; Tannhauser, M; Wainstein, M, 1990) |
| "Administration of imipramine, which blocks noradrenergic, serotonergic and cholinergic reuptake, to rats for 4 days counteracts the shuttlebox escape failures otherwise seen in rats which have been exposed to inescapable shock (the "learned helplessness" model of depression)." | 7.68 | Effect of imipramine in the "learned helplessness" model of depression in rats is not mimicked by combinations of specific reuptake inhibitors and scopolamine. ( Christensen, AV; Geoffroy, M; Scheel-Krüger, J, 1990) |
| "The role of the central histaminergic system in depression was studied by using swimming despair test in mice - a behavioural model of depression." | 7.67 | Role of central histaminergic mechanism in behavioural depression (swimming despair) in mice. ( Dhawan, KN; Gulati, A; Gupta, GP; Nath, C, 1988) |
| "We studied 45 depressed patients and 20 healthy controls in order to determine if tritiated imipramine binding distinguished among subtypes of primary major depressive disorder." | 7.67 | Tritiated imipramine binding distinguishes among subtypes of depression. ( Lewis, DA; McChesney, C, 1985) |
| "The response to imipramine (IMI) in children with depression has been shown to correlate with total levels of IMI plus its active metabolite desmethylimipramine (DMI)." | 7.67 | Targeting imipramine dose in children with depression. ( Perel, J; Rancurello, M; Sallee, F; Stiller, R, 1986) |
| "The authors reevaluate a large prospective Italian study (437 patients) that compared high-dose imipramine with ECT treatment in the treatment of depression." | 7.66 | Depression treated with imipramine and ECT: the DeCarolis study reconsidered. ( Avery, D; Lubrano, A, 1979) |
| "The introduction of two tricyclic compounds (iprindole and mianserin) that are reported to have antidepressant properties but to be relatively devoid of effects on central amine neurotransmitter systems has raised questions about the amine hypothesis of depression and about the mechanism of action of tricyclics in general." | 7.66 | Novel antidepressants and the biogenic amine hypothesis of depression. The case for iprindole and mianserin. ( Goodwin, FK; Zis, AP, 1979) |
| "In an open, uncontrolled trial flupenthixol was administered to 45 patients with endogenous depression." | 7.65 | Effect of flupenthixol on depression with special reference to combination use with tricyclic antidepressants. An uncontrolled pilot study with 45 patients. ( Baba, O; Fujiwara, J; Hanaoka, M; Ishino, H; Sasaki, K, 1976) |
| "Patients with Parkinson's syndrome whose major symptoms are akinesis, rigidity, inertia, depression, irritability and failure of adaptation rather than tremor appear to benefit in a global way from therapy with imipramine." | 7.64 | Parkinson's syndrome, depression and imipramine. A preliminary report. ( FOWLER, W; MANDELL, AJ; MARKHAM, C, 1961) |
| "Imipramine seems to be a better cost-utility antidepressant option for treating depressive disorders in primary care." | 6.74 | Fluoxetine and imipramine: are there differences in cost-utility for depression in primary care? ( Haro, JM; Peñarrubia, MT; Pinto-Meza, A; Serrano-Blanco, A; Suárez, D, 2009) |
| " Dosage was fixed for the first week at 50 mg t." | 6.65 | Comparisons of maprotiline with imipramine in severe depression: a multicenter controlled trial. ( Feighner, JP; Logue, JN; Sachais, BA, 1979) |
| "Depression is commonly associated with hypothalamic-pituitary adrenal (HPA) axis dysfunction that primarily manifests as aberrant glucocorticoid secretion." | 5.48 | Differential effects of imipramine and CORT118335 (Glucocorticoid receptor modulator/mineralocorticoid receptor antagonist) on brain-endocrine stress responses and depression-like behavior in female rats. ( Balmer, NJ; Caldwell, JL; Estrada, CM; Ghisays, V; Nguyen, ET; Solomon, MB; Streicher, J, 2018) |
| "Parkinson's disease is a chronic neurodegenerative disorder characterized by cardinal motor features, such as bradykinesia, but also vocal deficits (e." | 5.48 | Effects of ketamine on vocal impairment, gait changes, and anhedonia induced by bilateral 6-OHDA infusion into the substantia nigra pars compacta in rats: Therapeutic implications for Parkinson's disease. ( Andreatini, R; Bruginski, E; Campos, FR; de Almeida Soares Hocayen, P; Kanazawa, LKS; Miyoshi, E; Schwarting, RKW; Stern, CAJ; Vecchia, DD; Vital, MABF; Wendler, E; Wöhr, M, 2018) |
| "A total of 32 drug-free major depressive disorder patients and 30 healthy controls were recruited." | 5.46 | Decreased Prostaglandin D2 Levels in Major Depressive Disorder Are Associated with Depression-Like Behaviors. ( Chu, C; Shen, Y; Wei, H; Xu, Q; Zhu, W, 2017) |
| "A growing body of evidence has focused on the impact of mitochondrial disturbances in the development of depression, but little data exist regarding the effects of chronic administration of antidepressant drugs on the brain's mitochondrial protein profile." | 5.43 | The effect of chronic tianeptine administration on the brain mitochondria: direct links with an animal model of depression. ( Basta-Kaim, A; Budziszewska, B; Głombik, K; Kubera, M; Lasoń, W; Olszanecki, R; Ślusarczyk, J; Spedding, M; Stachowicz, A; Trojan, E, 2016) |
| "Depression is a common psychopathological disorders." | 5.43 | Zinc and imipramine reverse the depression-like behavior in mice induced by chronic restraint stress. ( Ding, Q; Huang, J; Li, H; Mo, F; Shen, H; Shen, Z; Tian, X; Wang, X, 2016) |
| " Additionally, the effects of chronic administration of the tricyclic antidepressant imipramine and the anti-TNF-α pentoxyphylline were investigated." | 5.40 | Lipopolysaccharide repeated challenge followed by chronic mild stress protocol introduces a combined model of depression in rats: reversibility by imipramine and pentoxifylline. ( Abd-Alkhalek, HA; Abdel-tawab, AM; Aboul-Fotouh, S; El Tabbal, M; Elgarf, AS; Farrag, KA; Hammouda, GA; Hassan, AN; Kassim, SK, 2014) |
| "Imipramine treatment significantly increased the number of neurons in the granule cell layer (GCL) and spine synapses in the CA1 in the FSL imipramine group (treated "depressed" rats) compared with the FSL saline group." | 5.36 | Imipramine treatment increases the number of hippocampal synapses and neurons in a genetic animal model of depression. ( Chen, F; Madsen, TM; Nyengaard, JR; Wegener, G, 2010) |
| "Imipramine treatment at 5 and 20 mg/kg/d enhanced BNIP3 mRNA expression only in the LH group but not in non-LH group or non-stressed group." | 5.36 | Enhanced expression of BCL2/adenovirus EIB 19-kDa-interacting protein 3 mRNA, a candidate for intrinsic depression-related factor, and effects of imipramine in the frontal cortex of stressed mice. ( Matsumoto, K; Mingmalairak, S; Murakami, Y; Tohda, M, 2010) |
| "Pretreatment with imipramine, MK 801 and ketamine significantly prevented the effect of shock." | 5.30 | Interaction between N-methyl-D-aspartate receptor antagonists and imipramine in shock-induced depression. ( Bapna, JS; Chandra, D; Chaturvedi, HK, 1999) |
| " The list includes diagnosis and patient selection; pharmacodynamics, bioavailability and tissue sensitivity; natural history; placebo response, nonspecific factors; compliance and adverse effects; the effects of concurrent life events, illness and treatment, and the bias in evaluating the outcome of treatment." | 5.26 | Factors influencing clinical response to psychotropic drugs. Imipramine in depression. ( Donlon, PT, 1979) |
| " Scopus, ISI, Embase, PubMed, Cochrane Library, Google Scholar, and two trial registries were searched for randomized controlled trials on the effectiveness of topiramate, phenobarbital, and other ten barbiturates in depression." | 5.22 | Topiramate and other kainate receptor antagonists for depression: A systematic review of randomized controlled trials. ( Shamabadi, A, 2022) |
| "Saffron at this dose was found to be effective similar to imipramine in the treatment of mild to moderate depression (F = 2." | 5.11 | Comparison of Crocus sativus L. and imipramine in the treatment of mild to moderate depression: a pilot double-blind randomized trial [ISRCTN45683816]. ( Afkham, K; Akhondzadeh, S; Fallah-Pour, H; Jamshidi, AH; Khalighi-Cigaroudi, F, 2004) |
| "The effect of aging on steady-state plasma concentrations of citalopram (CIT) and desmethylcitalopram (DCIT) was investigated in 128 depressive patients treated with 10-80 mg/day CIT." | 5.11 | Effect of age and gender on citalopram and desmethylcitalopram steady-state plasma concentrations in adults and elderly depressed patients. ( Baumann, P; Brawand-Amey, M; Brogli, C; Cochard, N; de Mendonça Lima, CA; Eap, CB; Jacquet, S; Powell-Golay, K, 2005) |
| "6 kg/m(2) [SD]) was designed to assess whether diet counseling with psychological support and imipramine or placebo has an effect on the frequency of binge eating, body weight, and depression during an 8-week treatment phase." | 5.09 | Imipramine and diet counseling with psychological support in the treatment of obese binge eaters: a randomized, placebo-controlled double-blind study. ( Graf, C; Horber, F; Laederach-Hofmann, K; Lederer, S; Lippuner, K; Michel, R; Schneider, M, 1999) |
| "To compare the efficacy and tolerability of Hypericum perforatum (St John's wort extract) with imipramine in patients with mild to moderate depression." | 5.09 | Comparison of St John's wort and imipramine for treating depression: randomised controlled trial. ( Woelk, H, 2000) |
| "Marital adjustment and treatment outcome were evaluated in the Treatment of Depression Collaborative Research Program, a multicenter clinical trial evaluating interpersonal psychotherapy, cognitive therapy, imipramine, and placebo." | 5.09 | Marital adjustment and outcome following treatments for depression. ( Whisman, MA, 2001) |
| " Twenty-four outpatients meeting DSM-III-R criteria for Major Depression received treatment with either fluvoxamine or imipramine for 6 weeks while participating in a placebo-controlled double-blind clinical trial." | 5.09 | Noradrenergic function and clinical outcome in antidepressant pharmacotherapy. ( Ekstrom, RD; Golden, RN; Lydiard, RB; Mason, GA; Miller, HL, 2001) |
| "This paper presents a cost-utility analysis of three maintenance treatments for recurrent depression: interpersonal therapy (IPT-M), imipramine drug therapy (Drug), and a combination of the two." | 5.08 | Cost utility analysis of maintenance treatment for recurrent depression. ( Frank, E; Greenhouse, J; Kamlet, MS; Kupfer, D; Paul, N; Wade, M, 1995) |
| " In a multicentre, 6 months, placebo-controlled trial, amisulpride (50 mg/daily) was compared to imipramine (100 mg/daily) in the treatment of patients with DSM-III-R criteria for primary dysthymia, dysthymia with major depression or major depression in partial remission." | 5.08 | Amisulpride versus imipramine and placebo in dysthymia and major depression. Amisulpride Study Group. ( Boyer, P; Lecrubier, Y; Rein, W; Turjanski, S, 1997) |
| "A double-blind, placebo-controlled study of 229 patients with a Research Diagnostic Criteria diagnosis of major, minor or intermittent depression was used to compare the clinical profiles of venlafaxine and imipramine in general practice." | 5.08 | Efficacy of venlafaxine in depressive illness in general practice. ( Blanchard, C; Bourin, M; Danjou, P; Hackett, D; Lecrubier, Y; Moon, CA; Schifano, F, 1997) |
| "Because depression with atypical features is poorly responsive to imipramine, treatment trials including a tricyclic antidepressant arm should assess depressive subtype." | 5.08 | Atypical features and treatment response in the National Institute of Mental Health Treatment of Depression Collaborative Research Program. ( Donovan, S; Garfinkel, R; Klein, DF; Nunes, EV; Stewart, JW, 1998) |
| "Thirty-seven patients participating in a controlled treatment study with imipramine were classified as high or low depressed simultaneously on two depression measures." | 5.06 | Initial depression and response to imipramine in agoraphobia. ( Mavissakalian, M, 1987) |
| "A double-blind controlled study was conducted to compare the effects of imipramine and placebo with trazodone, a new antidepressant, in 45 hospitalized patients with primary depression." | 5.05 | Trazodone, a triazolopyridine derivative, in primary depressive disorder. ( Feighner, JP, 1980) |
| "Endogenously depressed patients who showed an antidepressant response to the tricyclic drug imipramine continued to show sustained well being after alpha-MPT was added whereas depression returned when small doses of PCPA were added for brief periods." | 5.04 | Use of synthesis inhibitors in defining a role for biogenic amines during imipramine treatment in depressed patients. ( Friedman, E; Gershon, S; Goldstein, M; Shopsin, B; Wilk, S, 1975) |
| " Nomifensine, an isoquinoline dopaminergic agonist, was investigated in a randomized double-blind group comparison with imipramine, in 40 out-patients with depression." | 5.04 | Controlled randomized group comparison of nomifensine and imipramine in depressive illness. ( Forrest, A; Hewett, A; Nicholson, P, 1977) |
| "The authors examined how delusions and other psychotic features influenced treatment outcome with imipramine in patients with primary depression." | 5.04 | Imipramine response in deluded depressive patients. ( Klein, DF; Quitkin, F; Rifkin, A, 1978) |
| " Twenty-eight inpatients with a diagnosis of endogenous depression received either trazodone, imipramine, or placebo." | 5.04 | Trazodone, a new antidepressant: efficacy and safety in endogenous depression. ( Kellams, JJ; Klapper, MH; Small, JG, 1979) |
| "45 patients hospitalized for depression who had received double-blind trials with imipramine were examined for possible associations between pretreatment responses to the Minnesota Multiphasic Personality Inventory (MMPI) and their behaviorally-rated responses to this drug." | 5.04 | Prediction of antidepressant responses to imipramine. ( Donnelly, EF; Goodwin, FK; Murphy, DL; Waldman, IN, 1979) |
| "In patients with endogenous depression, imipramine exerts a regulative effect in both directions on blood pressure and pulse rate, dependent on the starting levels." | 5.04 | Influence of imipramine on the circulatory system in the course of endogenous depressive syndromes. I. Evaluation of the basic parameters of the circulatory system. ( Mrozikiewicz, A, 1975) |
| "The relationship between the antidepressive effect of imipramine and the plasma concentrations of imipramine and the active metabolite desipramine was studied in 24 patients suffering from endogenous depression." | 5.04 | Plasma levels and antidepressive effect of imipramine. ( Bech, P; Christiansen, J; Dencker, SJ; Gram, LF; Ibsen, I; Nagy, A; Petersen, GO; Reisby, N, 1976) |
| "The effect of lithium carbonate therapy on patients with depression is still unconfirmed." | 5.04 | Double-blind comparison of lithium carbonate and imipramine in treatment of depression. ( Ishino, H; Otsuki, S; Watanabe, S, 1975) |
| " A controlled, double-blind comparison of maprotiline and imipramine in a group of 71 female outpatients with primary depression is presented." | 5.04 | A controlled study of a tetracyclic antidepressant--maprotiline (Ludiomil). ( Holt, NF; Kessell, A, 1975) |
| " In addition to non-difference between drug-types, outcomes were unrelated to reporting-year, trial-size or nominal duration, proportion of women participants, initial depression ratings, rating scales, subjects/arm, imipramine-equivalent mg/day drug dose, or dropout rate." | 4.95 | Direct comparison of tricyclic and serotonin-reuptake inhibitor antidepressants in randomized head-to-head trials in acute major depression: Systematic review and meta-analysis. ( Baldessarini, RJ; Undurraga, J, 2017) |
| "The purpose of this study is to describe the clinical and light microscopic findings in 4 patients with imipramine-induced hyperpigmentation and to better understand its origin." | 4.80 | Imipramine-induced hyperpigmentation: four cases and a review of the literature. ( Bhawan, J; Cohen, LM; McCalmont, TH; Ming, ME; Stefanato, CM, 1999) |
| "Mianserin is a tetracyclic compound advocated for the treatment of depressive illness and depression associated with anxiety." | 4.75 | Mianserin: a review of its pharmacological properties and therapeutic efficacy in depressive illness. ( Avery, GS; Brogden, RN; Heel, RC; Speight, TM, 1978) |
| "Both low-dose LBP and imipramine decreased depression-like behavior by increasing serum superoxide dismutase activity and by decreasing serum malondialdehyde level." | 4.31 | Neuroprotective effects of goji berry (Lycium barbarum L.) polysaccharides on depression-like behavior in ovariectomized rats: behavioral and biochemical evidence. ( Bozat, BG; Coskun, H; Firat, T; Pehlivan Karakas, F; Soytürk, H, 2023) |
| "Considering that serotoninergic agents attenuate symptoms of anxiety and are used to treat depression, we investigated whether subchronic treatment with imipramine, a serotonin/noradrenaline reuptake inhibitor, would prevent the anxiogenic-like behaviour induced by acute and/or chronic ethanol withdrawal." | 4.02 | Imipramine attenuates anxiety- and depressive-like effects of acute and prolonged ethanol-abstinence in male rats by modulating SERT and GR expression in the dorsal hippocampus. ( Anselmo-Franci, JA; Campos-Cardoso, R; Carolino, ROG; Padovan, CM; Silva, CPB; Tirapelli, CR, 2021) |
| "Imipramine is a tricyclic antidepressant (TCA) drug that is sometimes used to treat neuropathic pain." | 4.02 | Synergistic effect between imipramine and citicoline upon induction of analgesic and antidepressant effects in mice. ( Khakpai, F; Ramezanikhah, M; Valizadegan, F; Zarrindast, MR, 2021) |
| "We used a rat prenatal stress (PS) model of depression to explore the functional role of mGluR5 in ketamine's rapidly induced antidepressant activity." | 3.96 | mGluR5 mediates ketamine antidepressant response in susceptible rats exposed to prenatal stress. ( Cao, Y; Che, F; He, W; Sun, H; Wang, Y; Yao, Z; Zhang, H, 2020) |
| "A recent review proposed four criteria for an animal model of treatment-resistant depression (TRD): a phenotypic resemblance to a risk factor for depression; enhanced response to stress; nonresponse to antidepressant drugs and response to treatments effective in TRD, such as deep brain stimulation (DBS) of the prefrontal cortex or ketamine." | 3.91 | Validation of chronic mild stress in the Wistar-Kyoto rat as an animal model of treatment-resistant depression. ( Gruca, P; Lason, M; Litwa, E; Niemczyk, M; Papp, M; Tota-Glowczyk, K; Willner, P, 2019) |
| " Imipramine treatment was able to reverse depressive- and anxiety-like behaviors." | 3.91 | Imipramine treatment reverses depressive- and anxiety-like behaviors, normalize adrenocorticotropic hormone, and reduces interleukin-1β in the brain of rats subjected to experimental periapical lesion. ( Barichello, T; Ceretta, RA; Dal-Pizzol, F; Dominguini, D; Generoso, JS; Michels, M; Netto, S; Réus, GZ; Simões, LR; Valim, RF; Valvassori, SS, 2019) |
| "Depression is associated with dysregulation of methyl group metabolism such as low S-adenosylmethionine (SAM)." | 3.91 | Behavioral and metabolic effects of S-adenosylmethionine and imipramine in the Flinders Sensitive Line rat model of depression. ( Geisel, J; Happ, DF; Mikkelsen, PF; Obeid, R; Tillmann, S; Wegener, G, 2019) |
| "Lithium has been shown to have some therapeutic efficacy as an adjunctive treatment for intractable forms of major depression." | 3.91 | Insulin-stimulated mTOR activation in peripheral blood mononuclear cells associated with early treatment response to lithium augmentation in rodent model of antidepressant-resistance. ( Borreggine, K; Frye, MA; Gogos, A; McGillivray, JA; Price, JB; Sutor, SL; Tye, SJ; Walker, AJ, 2019) |
| " We studied the antidepressant-like and pro-cognitive effects of raw GM rind in Flinders Sensitive Line (FSL) rats, a genetic model of depression, following acute and chronic treatment compared to a reference antidepressant, imipramine (IMI)." | 3.88 | Garcinia mangostana Linn displays antidepressant-like and pro-cognitive effects in a genetic animal model of depression: a bio-behavioral study in the Flinders Sensitive Line rat. ( Berk, M; Dean, OM; Harvey, BH; Holland, B; Möller, M; Oberholzer, I, 2018) |
| "Our goal was to find out the impact of two antidepressant drugs with various mechanisms of action - imipramine and fluoxetine, on the frontal cortex mitochondria-enriched fraction in an animal model of depression based on the prenatal stress procedure." | 3.88 | Mitochondrial proteomics investigation of frontal cortex in an animal model of depression: Focus on chronic antidepressant drugs treatment. ( Basta-Kaim, A; Chamera, K; Głombik, K; Kotarska, K; Olszanecki, R; Ślusarczyk, J; Stachowicz, A; Suski, M; Trojan, E, 2018) |
| " Imipramine was administered for the next 5 weeks, and it reversed anhedonia in majority of animals (imipramine-reactive); however, in some animals, it did not (imipramine-non-reactive)." | 3.88 | Regulation of somatostatin receptor 2 in the context of antidepressant treatment response in chronic mild stress in rat. ( Antkiewicz-Michaluk, L; Dziedzicka-Wasylewska, M; Faron-Górecka, A; Gruca, P; Kolasa, M; Kuśmider, M; Pabian, P; Papp, M; Romańska, I; Solich, J; Szlachta, M; Żurawek, D, 2018) |
| " In CMS, anhedonia in rats is manifested by reduced consumption of sucrose solution while administration of antidepressant drugs reverses anhedonia." | 3.85 | Basal prolactin levels in rat plasma correlates with response to antidepressant treatment in animal model of depression. ( Dziedzicka-Wasylewska, M; Faron-Górecka, A; Gruca, P; Kolasa, M; Kuśmider, M; Pabian, P; Papp, M; Solich, J; Szafran-Pilch, K; Żurawek, D, 2017) |
| "In this study adult female Wistar and Wistar-Kyoto (WKY) rats, a putative animal model of depression, were exposed to alcohol vapor 3h daily for 10days (blood alcohol concentration ∼150mg%) followed by daily injection of 10mg/kg of imipramine (IMP, a selective norepinephrine NE/serotonin reuptake inhibitor) or nomifensine (NOMI, a selective NE/dopamine reuptake inhibitor)." | 3.85 | Role of cortical alpha-2 adrenoceptors in alcohol withdrawal-induced depression and tricyclic antidepressants. ( Csoka, AB; Getachew, B; Hauser, SR; Taylor, RE; Tizabi, Y, 2017) |
| " However, vital safety and efficacy issues related to combined therapy with temozolomide, the first-line cytostatic in patients diagnosed with glioblastoma multiforme, and antidepressant drugs have yet to be addressed." | 3.85 | Antidepressant drugs can modify cytotoxic action of temozolomide. ( Bielecka, AM; Obuchowicz, E, 2017) |
| "Agmatine, an endogenous neuromodulator, is a potential candidate to constitute an adjuvant/monotherapy for the management of depression." | 3.83 | Agmatine, by Improving Neuroplasticity Markers and Inducing Nrf2, Prevents Corticosterone-Induced Depressive-Like Behavior in Mice. ( Buendia, I; Casas, AI; Cuadrado, A; Egea, J; Freitas, AE; Gómez-Rangel, V; Lopez, MG; Navarro, E; Ortiz, JA; Parada, E; Rodrigues, ALS; Ruiz-Nuño, A; Wojnicz, A, 2016) |
| "We investigated whether tipepidine exerts an antidepressant-like effect in the forced swimming test in adrenocorticotropic hormone (ACTH)-treated rats, which is known as a treatment-resistant depression model, and we studied the pharmacological mechanisms of the effects of tipepidine." | 3.83 | Tipepidine, a non-narcotic antitussive, exerts an antidepressant-like effect in the forced swimming test in adrenocorticotropic hormone-treated rats. ( Honda, S; Kawaura, K; Ogata, Y; Shirasaki, T; Soeda, F; Takahama, K, 2016) |
| "The aim of the present study was to investigate the effects of ketamine, imipramine, and ketamine plus imipramine on chronic depression-like behaviors of Wistar Kyoto (WKY) rats and underlying mechanism." | 3.83 | [Effects of ketamine, imipramine, and their combination on depression-like behaviors in Wistar Kyoto rats]. ( Jin, XJ; Li, QQ; Peng, LC; Ye, K, 2016) |
| "A new (aryloxyalkyl)adenine derivative Adeprophen (9-[2-(4-isopropylphenoxy)ethyl]adenine, VMA-99-82) has a strong antidepressant effect on the model of reserpine-induced depression in rats (single dose 4 mg/kg, intraperitoneally)." | 3.83 | Comparison of the Efficiency of Adeprophen and Antidepressants of Various Groups on the Model of Reserpine-Induced Depression in Rats. ( Bagmetova, VV; Chernysheva, YV; Ozerov, AA; Tyurenkov, IN, 2016) |
| "In order to relieve anxiety and depression accompanying stress, physicians resort to tricyclic antidepressants, such as imipramine." | 3.83 | Antidepressant imipramine diminishes stress-induced inflammation in the periphery and central nervous system and related anxiety- and depressive- like behaviors. ( Ramirez, K; Sheridan, JF, 2016) |
| " These observations led us to suggest - and later confirm - with preliminary clinical observations that memantine may have an acute antimanic and a long-lasting mood-stabilizing effect in treatment-resistant bipolar disorder patients." | 3.81 | Memantine prevents "bipolar-like" behavior induced by chronic treatment with imipramine in rats. ( Canu, D; Demontis, F; Falconi, M; Serra, G, 2015) |
| "In the present study, the amino acids which have the possibility for the therapeutic efficacy of imipramine were explored and compared between Wistar Kyoto rats, an animal model of depression, and Wistar rats as a normal model." | 3.81 | Chronic imipramine treatment differentially alters the brain and plasma amino acid metabolism in Wistar and Wistar Kyoto rats. ( Furuse, M; Nagasawa, M; Otsuka, T; Yasuo, S, 2015) |
| "Thus, our results suggest that the reduced IL-4 and IL-10 levels in serum with hippocampal M2 markers may be involved in the stress vulnerability after imipramine discontinuation, and the restoration and modulation of these factors may be useful to some forms of depression-associated conditions." | 3.81 | IL-4/10 prevents stress vulnerability following imipramine discontinuation. ( Choi, HJ; Han, A; Hong, CW; Kim, SH; Kwon, MS; Park, MJ; Yeo, H, 2015) |
| "Atorvastatin is a synthetic and lipophilic statin which has been reported to have a positive role in reducing depression." | 3.80 | Antidepressant-like effect of atorvastatin in the forced swimming test in mice: the role of PPAR-gamma receptor and nitric oxide pathway. ( Dehpour, A; Jahanabadi, S; Javadi, S; Khoshnoodi, M; Mehr, SE; Shafaroodi, H; Shahsavarian, A; Shamsaee, J, 2014) |
| " However, little is known about the neuroanatomy underlying the mechanism of the imipramine treatment-resistant depression model." | 3.79 | Imipramine-induced c-Fos expression in the medial prefrontal cortex is decreased in the ACTH-treated rats. ( Araki, H; Cui, R; Gomita, Y; Kitamura, Y; Li, B; Suemaru, K, 2013) |
| "The effects of ladasten and reference product imipramine (10 mg/kg) on the content of cytokines TNF-α, IL-6, IL-10, IL-1α, IL-2, IL-4, IL-5, IL-17, IFN-γ, and GM-CSF and behavior of male C57Bl/6 mice were studied on the model of a depression-like state induced by a single intraperitoneal injection of bacterial LPS in a dose of 100 μg/kg." | 3.77 | Effect of ladasten on the content of cytokine markers of inflammation and behavior of mice with experimental depression-like syndrome. ( Durnev, AD; Kovalenko, LP; Seredenin, SB; Tallerova, AV, 2011) |
| " We tested if blockade or activation of serotonin (5-HT)(2) receptors affected the time of immobility (as an indirect measure of depression-like behavior) in naïve animals and in those withdrawn from chronic nicotine in the forced swim test (FST)." | 3.76 | Effects of serotonin (5-HT)2 receptor ligands on depression-like behavior during nicotine withdrawal. ( Filip, M; McCreary, AC; Wydra, K; Zaniewska, M, 2010) |
| "Clinical findings suggest that ketamine may be used for the treatment of major depression." | 3.75 | Effect of acute administration of ketamine and imipramine on creatine kinase activity in the brain of rats. ( Assis, LC; Comim, CM; Jeremias, IC; Quevedo, J; Rezin, GT; Streck, EL; Valvassori, SS; Zugno, AI, 2009) |
| "To evaluate the antidepressant effect of imipramine on depressive symptoms observed in sepsis survivors rats." | 3.74 | Imipramine reverses the depressive symptoms in sepsis survivor rats. ( Antunes, MM; Comim, CM; Constantino, LS; Dal-Pizzol, F; Izquierdo, I; Machado, RA; Quevedo, J; Tuon, L, 2007) |
| "Cholecystokinin (CCK) involvement in depression-like disorders is poorly documented." | 3.74 | Repeated social defeat-induced depression-like behavioral and biological alterations in rats: involvement of cholecystokinin. ( Becker, C; Benoliel, JJ; Blugeot, A; Hamon, M; Rivat, C; Zeau, B, 2008) |
| "The use of carbamazepine has been reported to be an effective treatment for severe depression." | 3.74 | Chronic coadministration of carbamazepine together with imipramine produces antidepressant-like effects in an ACTH-induced animal model of treatment-resistant depression: involvement of 5-HT(2A) receptors? ( Akiyama, K; Araki, H; Gomita, Y; Kawasaki, H; Kitagawa, K; Kitamura, Y; Sendo, T; Shibata, K; Suemaru, K, 2008) |
| "A dysregulated hypothalamic-pituitary-adrenal axis (HPA) has been implicated in major depressive disorder and most commonly used animal models of depression have been shown to elevate circulating levels of plasma corticosterone." | 3.74 | Chronic low dose corticosterone exposure decreased hippocampal cell proliferation, volume and induced anxiety and depression like behaviours in mice. ( Hutson, PH; Murray, F; Smith, DW, 2008) |
| "3." | 3.74 | A review of controlled studies with nomifensine, performed outside the UK. ( Habermann, W, 1977) |
| "To investigate the relationship between platelet [3H]-imipramine binding and Beck Depression Inventory scores in the premenstrual syndrome (PMS)." | 3.73 | Serotonergic activity and the Beck Depression Inventory in the premenstrual syndrome. ( Engin-Ustün, Y; Güngör, M; Gürdal, H; Ustün, Y, 2005) |
| "To better understand the molecular mechanisms of depression and antidepressant action, we administered chronic social defeat stress followed by chronic imipramine (a tricyclic antidepressant) to mice and studied adaptations at the levels of gene expression and chromatin remodeling of five brain-derived neurotrophic factor (Bdnf) splice variant mRNAs (I-V) and their unique promoters in the hippocampus." | 3.73 | Sustained hippocampal chromatin regulation in a mouse model of depression and antidepressant action. ( Berton, O; Kumar, A; Nestler, EJ; Neve, RL; Renthal, W; Tsankova, NM, 2006) |
| "Putrescine, a polyamine present at high concentrations in the mammalian brain, was suggested to play a role in the modulation of depression." | 3.73 | Putrescine produces antidepressant-like effects in the forced swimming test and in the tail suspension test in mice. ( Rodrigues, AL; Santos, AR; Zomkowski, AD, 2006) |
| "We describe a patient with facial pigmentation of 26 years' duration that was associated with imipramine treatment for depression." | 3.73 | Imipramine-induced facial pigmentation: case report and literature review. ( Lin, AN; Metelitsa, AI; Nguyen, GK, 2005) |
| " The role played by its components, particularly hypericin and hyperforin, has been examined in different experimental models of depression." | 3.72 | Hypericum perforatum subspecies angustifolium shows a protective activity on the consequences of unavoidable stress exposure at lower doses than Hypericum perforatum perforatum. ( De Montis, MG; Gambarana, C; Giachetti, D; Grappi, S; Leggio, B; Nanni, G; Tolu, P; Usai, M, 2003) |
| " Syt IV (-/-) mice also exhibit reduced depression-like behavior and are highly sensitive to the effects of the anti-depressant imipramine in a modified Porsolt forced swim test." | 3.72 | Reduced anxiety and depression-like behavior in synaptotagmin IV (-/-) mice. ( Ferguson, GD; Herschman, HR; Storm, DR, 2004) |
| "Imipramine as the positive contrast medicine, effects of MC on the depression behavior of mice were observed by forced swimming test and reserpine antagonist test." | 3.72 | [Effect of madecassoside on depression behavior of mice and activities of MAO in different brain regions of rats]. ( Chen, Y; Han, T; Liu, MR; Qin, LP; Rui, YC; Zheng, HC, 2004) |
| "Two women, aged 65 and 43 years, who were suffering from tricyclic-resistant depressions, developed a (hypo)manic state after a few days of lithium addition." | 3.71 | [Manic state during the addition of lithium in the case of depression resistant to imipramine]. ( Beck-Lie A Fat, JR; Birkenhäger, TK; Renes, JW, 2002) |
| "The purpose of this study was to examine the metabolites of lofepramine (LOF), namely desipramine (DMI), desmethyl desipramine (DDMI) and desmethyl lofepramine (DML) in the forced swim and olfactory bulbectomized (OB) rat models of depression." | 3.70 | An investigation of the antidepressant properties of lofepramine and its desmethylated metabolites in the forced swim and olfactory bulbectomized rat models of depression. ( Kelly, JP; Leonard, BE, 1999) |
| "A chronic mild stress (CMS) model of depression was used to study an antidepressant-like activity of alnespirone (S 20499), a selective agonist of 5-HT1A receptors." | 3.70 | Alnespirone (S 20499), an agonist of 5-HT1A receptors, and imipramine have similar activity in a chronic mild stress model of depression. ( Muñoz, C; Papp, M, 1999) |
| " In addition, hypericum extracts, as well as standard antidepressants such as the tricyclic, impramine, and the selective serotonin reuptake inhibitor, fluoxetine, have been reported to be of therapeutic benefit in the treatment of alcoholism, as these compounds may reduce alcohol craving and/or intake in particular subgroups of patients." | 3.70 | Comparison of hypericum extracts with imipramine and fluoxetine in animal models of depression and alcoholism. ( de Beun, R; De Vry, J; Jentzsch, KR; Maurel, S; Schreiber, R, 1999) |
| "A standardised 50% aqueous ethanolic extract of Indian Hypericum perforatum (IHp) was investigated for its antidepressant activity on various experimental paradigms of depression, viz." | 3.70 | Antidepressant activity of Indian Hypericum perforatum Linn in rodents. ( Bhattacharya, SK; Jaiswal, AK; Kumar, V; Singh, PN, 1999) |
| "The selective sigma2 (sigma2) ligand Lu 28-179, or 1'-[4[1-(4-fluorophenyl)-1H-indol-3-yl]-l-butyl]spiro[isobenzofuran++ +-1(3H),4'-piperidine], was studied in the chronic mild stress (CMS) model of depression." | 3.70 | The selective sigma2 ligand Lu 28-179 has an antidepressant-like profile in the rat chronic mild stress model of depression. ( Papp, M; Sánchez, C, 2000) |
| "Epidemiological studies of smokers suggest that there is a link between nicotine and depression." | 3.70 | Antidepressant-like effects of the subtype-selective nicotinic acetylcholine receptor agonist, SIB-1508Y, in the learned helplessness rat model of depression. ( Brodkin, JD; Ferguson, SM; Lloyd, GK; Menzaghi, F, 2000) |
| " We corroborated some previous findings that CMS, which had been used as an animal model of depression, decreased the consumption of a 1% sucrose solution and that that effect was reversed by chronic administration of imipramine." | 3.69 | The effect of chronic treatment with imipramine on the responsiveness of hippocampal CA1 neurons to phenylephrine and serotonin in a chronic mild stress model of depression. ( Bijak, M; Papp, M, 1995) |
| "HCl), and that of imipramine in the behavioural despair model of depression." | 3.69 | Antidepressant-like effect of selective dopamine D1 receptor agonists in the behavioural despair animal model of depression. ( Collu, M; D'Aquila, PS; Gessa, GL; Pani, L; Serra, G, 1994) |
| "The antidepressant properties of the non-competitive NMDA receptor antagonist, MK-801 (dizocilpine), and the competitive NMDA receptor antagonist, CGP 37849 (DL-(E)-2-amino-4-methyl-5-phosphono-3-pentonoic acid) and its (R)-enantiomer CGP 40116, were studied in a chronic mild stress model of depression." | 3.69 | Antidepressant activity of non-competitive and competitive NMDA receptor antagonists in a chronic mild stress model of depression. ( Moryl, E; Papp, M, 1994) |
| " We present a case of massive imipramine overdose complicated by ventricular fibrillation and a prolonged period of cardiovascular collapse." | 3.69 | Tricyclic poisoning--successful management of ventricular fibrillation following massive overdose of imipramine. ( Alahakoon, TI; Bentley, SC; Sandeman, DJ, 1997) |
| "The response to treatment with imipramine or clonazepam was evaluated in patients with panic disorder." | 3.68 | [Treatment of patients with panic disorder and an elevated urinary excretion of MHPG using imipramine or clonazepam]. ( Carreira, I; Casique, M; Lima, L; Morales, M; Silva, C, 1992) |
| "The present study was conducted to examine whether a chronic variable stress procedure (CVS)--an animal model of depression--facilitates tumor growth, and whether this effect can be modified by concurrent administration of the antidepressant imipramine (IMI)." | 3.68 | Chronic variable stress facilitates tumoral growth: reversal by imipramine administration. ( Basso, AM; Depiante-Depaoli, M; Molina, VA, 1992) |
| "Platelet [3H]imipramine binding was measured in 40 migrainous (7 classical and 33 common) and 17 tension headache patients and in 28 normal controls." | 3.68 | Platelet [3H]imipramine binding in migraine and tension headache in relation to depression. ( Davies, PT; Fernandez, M; Glover, V; Jarman, J; Rose, FC; Sandler, M; Steiner, TJ, 1991) |
| "Tritiated imipramine binding in platelets has been used to evaluate serotonin activity in depression in previous studies." | 3.68 | Tritiated imipramine binding. A peripheral marker for serotonin in Parkinson's disease. ( Coté, L; Lawton, A; Marder, K; Mayeux, R; Sano, M; Stanley, M; Stern, Y; Williams, J, 1991) |
| "Long-term (33-35 days) castration caused a significant increase in the duration of immobility of male and female mice in the tail suspension test (an animal model of depression), and a significant decrease in the maximum number (Bmax) of [3H]imipramine binding sites in the cerebral cortex of male mice." | 3.68 | Influence of gonadotropin-releasing hormone on castration-induced 'depression' in mice: a behavioral and binding study. ( Bernardi, M; Bertolini, A; Marrama, D; Sandrini, M; Tagliavini, S; Vergoni, AV, 1990) |
| " Imipramine and mianserine potentiated amphetamine-induced anorexia both after acute administration or after prolonged previous treatment with each drug." | 3.68 | Lack of tolerance to imipramine or mianserine in two animal models of depression. ( Barros, HM; Tannhauser, M; Wainstein, M, 1990) |
| "Administration of imipramine, which blocks noradrenergic, serotonergic and cholinergic reuptake, to rats for 4 days counteracts the shuttlebox escape failures otherwise seen in rats which have been exposed to inescapable shock (the "learned helplessness" model of depression)." | 3.68 | Effect of imipramine in the "learned helplessness" model of depression in rats is not mimicked by combinations of specific reuptake inhibitors and scopolamine. ( Christensen, AV; Geoffroy, M; Scheel-Krüger, J, 1990) |
| "The role of the central histaminergic system in depression was studied by using swimming despair test in mice - a behavioural model of depression." | 3.67 | Role of central histaminergic mechanism in behavioural depression (swimming despair) in mice. ( Dhawan, KN; Gulati, A; Gupta, GP; Nath, C, 1988) |
| "We studied 45 depressed patients and 20 healthy controls in order to determine if tritiated imipramine binding distinguished among subtypes of primary major depressive disorder." | 3.67 | Tritiated imipramine binding distinguishes among subtypes of depression. ( Lewis, DA; McChesney, C, 1985) |
| "The response to imipramine (IMI) in children with depression has been shown to correlate with total levels of IMI plus its active metabolite desmethylimipramine (DMI)." | 3.67 | Targeting imipramine dose in children with depression. ( Perel, J; Rancurello, M; Sallee, F; Stiller, R, 1986) |
| " We present a case of significant behavioral side effects in a young woman secondary to elevated plasma levels of imipramine and desipramine, masquerading as an agitated psychotic depression." | 3.67 | Profound behavioral toxicity due to tricyclic antidepressants. ( Grunhaus, L; Meador-Woodruff, JH, 1986) |
| "Case reports are presented of two depressed patients with probable bipolar disorder who did not respond to trazodone but developed mania when this drug was abruptly replaced with imipramine." | 3.67 | Mania following change from trazodone to imipramine. ( Haggerty, JJ; Jackson, R, 1985) |
| " An animal model of depression is induced, in rats, by systemic injection of low doses of apomorphine." | 3.66 | [Role of the amygdala in the sedation induced by low doses of apomorphine]. ( Foti, D; Giammona, G; Nicoletti, F; Patti, F; Rampello, L; Sortino, MA; Tigano, G, 1983) |
| " The results indicate that chronic administration of imipramine or of electroshock led to the abolition of the behavioural depression and of the EEG synchronisation induced by clonidine." | 3.66 | Effects of chronic treatment with imipramine, trazodone and electroshock on the behavioural and electroencephalographic modifications induced by clonidine in the rat. ( Passarelli, F; Scotti de Carolis, A, 1983) |
| "To further test the new hypersensitive postsynaptic serotonin (5-HT) receptor theory of depression bases on or animal model, it was necessary to demonstrate that some of the currently used antidepressive drugs can block D,L-5-hydroxytryptophan (5-HTP) induced depression acting through postsynaptic rather than presynaptic mechanisms." | 3.66 | Postsynaptic action by four antidepressive drugs in an animal model of depression. ( Aprison, MH; Hingtgen, JN; Nagayama, H, 1981) |
| "An analysis was made of the occurrence of anticholinergic side effects in 15 multicenter studies of 379 patients with endogenous depression who received either trazodone, imipramine, or placebo." | 3.66 | Lack of anticholinergic side effects with a new antidepressent--trazodone. ( Gershon, S; Newton, R, 1980) |
| "The authors reevaluate a large prospective Italian study (437 patients) that compared high-dose imipramine with ECT treatment in the treatment of depression." | 3.66 | Depression treated with imipramine and ECT: the DeCarolis study reconsidered. ( Avery, D; Lubrano, A, 1979) |
| "The introduction of two tricyclic compounds (iprindole and mianserin) that are reported to have antidepressant properties but to be relatively devoid of effects on central amine neurotransmitter systems has raised questions about the amine hypothesis of depression and about the mechanism of action of tricyclics in general." | 3.66 | Novel antidepressants and the biogenic amine hypothesis of depression. The case for iprindole and mianserin. ( Goodwin, FK; Zis, AP, 1979) |
| "The electrocardiographic effects of imipramine hydrochloride at therapeutic plasma concentrations were determined in 44 depressed patients during a 6-week clinical outcome study of depression." | 3.66 | The electrocardiographic and antiarrhythmic effects of imipramine hydrochloride at therapeutic plasma concentrations. ( Bigger, JT; Giardina, EG; Glassman, AH; Kantor, SJ; Perel, JM, 1979) |
| "A case of agranulocytosis associated with Imipramine use is reported." | 3.66 | Agranulocytosis associated with tricyclics. ( Albertini, RS; Penders, TM, 1978) |
| "Although the FDA recommends imipramine hydrochloride (IMI) only for temporary relief of symptoms of enuresis nocturna (EN), the drug has been applied to a number of other pediatric situations, including the Hyperkinetic Syndrome (HS), childhood depression, somnambulism and pavor nocturnus, school phobia, petit mal epilepsy, allergies, autism, encorpresis and head-banging." | 3.65 | Imipramine and children: a review and some speculations about the mechanism of drug action. ( Gualtieri, CT, 1977) |
| "Ten patients with psychotic depression were assessed on a battery of clinical, EEG, psychological, and biochemical measures during treatment with imipramine (150 mg/day)." | 3.65 | The electroencephalographic and psychological effects of imipramine in depressed inpatients. ( Bhanji, S; Lader, M, 1977) |
| "001) in a group of 11 male patients with primary depression after 3 weeks of treatment with either amitriptyline or imipramine." | 3.65 | In vivo inhibition of platelet MAO activity by tricyclic antidepressants. ( Dackis, C; Stanfield, C; Sullivan, JL, 1977) |
| "In an open, uncontrolled trial flupenthixol was administered to 45 patients with endogenous depression." | 3.65 | Effect of flupenthixol on depression with special reference to combination use with tricyclic antidepressants. An uncontrolled pilot study with 45 patients. ( Baba, O; Fujiwara, J; Hanaoka, M; Ishino, H; Sasaki, K, 1976) |
| " In latent of manifest glaucoma (7 patients) Clomipramine increased the tonography in 1 case, whereas Amitriptyline and Noxiptiline reduced it in 4 cases." | 3.65 | [Psychotropic drugs and glaucoma (author's transl)]. ( Andrée, G; Meiser, H; Schmitt, W, 1976) |
| "In patients with endogenous depression imipramine normalizes vascular responses in vegetative tests (orthostatic test, Schellong's test, cold pressor test)." | 3.65 | Influence of imipramine on the circulatory system in the course of endogenous depressive syndromes. II. Influence of imipramine on vascular reflexes. ( Mrozikiewicz, A; Strzyzewski, W, 1975) |
| " Cardiac arrhythmias induced in children by amitriptyline and imipramine are prominent and dangerous." | 3.65 | Amitriptyline and imipramine poisoning in children. ( Goel, KM; Shanks, RA, 1974) |
| "Measures of subjective feeling used by five patients indicated that depression of mood occurred about four days after fenfluramine withdrawal." | 3.65 | Drugs of dependence though not of abuse: fenfluramine and imipramine. ( Brezinova, V; Briggs, M; Dunleavy, DL; Lewis, SA; Oswald, I, 1971) |
| "Patients with Parkinson's syndrome whose major symptoms are akinesis, rigidity, inertia, depression, irritability and failure of adaptation rather than tremor appear to benefit in a global way from therapy with imipramine." | 3.64 | Parkinson's syndrome, depression and imipramine. A preliminary report. ( FOWLER, W; MANDELL, AJ; MARKHAM, C, 1961) |
| "Tricyclic antidepressants (TCA) continue to be an important group of drugs, but it is unclear whether a dose-response relationship is supported by high-level evidence." | 2.82 | Dose effects of tricyclic antidepressants in the treatment of acute depression - A systematic review and meta-analysis of randomized trials. ( Baethge, C; Braun, C; Bschor, T; Henssler, J; Rink, L; Schwarzer, G, 2022) |
| "Despite significant advances in the treatment of major depression, there is a high degree of variability in how patients respond to treatment." | 2.76 | Prognostic prediction of therapeutic response in depression using high-field MR imaging. ( Gong, Q; Huang, X; Jia, Z; Lui, S; Marquand, A; McGuire, P; Mechelli, A; Scarpazza, C; Wu, Q, 2011) |
| "Twenty-three elderly patients with type 2 diabetes and hypomagnesemia were enrolled and randomly allocated to receive either 50 mL of MgCl2 5% solution equivalent to 450 mg of elemental magnesium or Imipramine 50 mg daily during 12 weeks." | 2.73 | Efficacy and safety of oral magnesium supplementation in the treatment of depression in the elderly with type 2 diabetes: a randomized, equivalent trial. ( Barragán-Rodríguez, L; Guerrero-Romero, F; Rodríguez-Morán, M, 2008) |
| "Gabapentin 2400 mg/day was given in case of treatment failure or if imipramine treatment was not possible." | 2.71 | Therapeutic outcome in neuropathic pain: relationship to evidence of nervous system lesion. ( Bach, FW; Jensen, TS; Rasmussen, PV; Sindrup, SH, 2004) |
| "Imipramine was more effective against the clusters related to core symptoms of depression: "depression and guilt", "retardation", and "melancholia", respectively." | 2.69 | Depressed in-patients respond differently to imipramine and mirtazapine. ( Bruijn, JA; Moleman, P; Mulder, PG; van den Broek, WW, 1999) |
| "Paroxetine is a potent inhibitor of serotonin re-uptake." | 2.68 | Paroxetine in the treatment of Chinese patients with depressive episode: a double-blind randomized comparison with imipramine. ( Chan, CH; Chiu, HJ; Hong, CJ, 1996) |
| " The dosage was 3 x 300 mg hypericum extract LI 160 or 3 x 25 mg imipramine daily." | 2.67 | Effectiveness and tolerance of the hypericum extract LI 160 in comparison with imipramine: randomized double-blind study with 135 outpatients. ( Arnoldt, KH; Hübner, WD; Vorbach, EU, 1994) |
| "Paroxetine was given as a fixed dose of 40 mg/day, while the dose of imipramine was adjusted to yield optimal plasma levels of imipramine plus desipramine of 400-600 nM." | 2.67 | The selective serotonin reuptake inhibitor paroxetine is effective in the treatment of diabetic neuropathy symptoms. ( Brøsen, K; Eshøj, O; Gram, LF; Mogensen, EF; Sindrup, SH, 1990) |
| "The alprazolam effects were apparent by week 1; the imipramine effects by week 4." | 2.67 | Cardiovascular and symptomatic reduction effects of alprazolam and imipramine in patients with panic disorder: results of a double-blind, placebo-controlled trial. ( Agras, WS; Clark, D; Ehlers, A; Hayward, C; King, R; Maddock, R; Margraf, J; Roth, WT; Taylor, CB, 1990) |
| "Treatment with imipramine inhibited metabolism of both sparteine and debrisoquine (MR values about doubled), but did not affect the interpatient correlations." | 2.66 | Steady-state concentrations of imipramine and its metabolites in relation to the sparteine/debrisoquine polymorphism. ( Bech, P; Bertilsson, L; Brøsen, K; Gram, LF; Klysner, R; Otton, SV, 1986) |
| " These unexpected adverse behavioral effects were discussed with respect to dosage and diagnostic considerations." | 2.66 | Preliminary study of imipramine in profoundly retarded residents. ( Aman, MG; Teehan, CJ; Vaithianathan, C; White, AJ, 1986) |
| " The dosage schedule provided an initial dose of 2 capsules/day which was to be gradually increased up to a maximum dose of 9 capsules/day." | 2.66 | Diclofensine and imipramine. A double-blind comparative trial in depressive out-patients. ( Capponi, R; Hormazabal, L; Schmid-Burgk, W, 1985) |
| "Endogenous anxiety (anxiety hysteria, agoraphobia with panic attacks) is characterized by sudden, spontaneous panic attacks accompanied by multiple autonomic symptoms, overwhelming fear, a flight response, and polyphobic behavior." | 2.65 | Treatment of endogenous anxiety with phobic, hysterical, and hypochondriacal symptoms. ( Ballenger, J; Jacobsen, G; Sheehan, DV, 1980) |
| "Amoxapine was inferior to imipramine as an inhibitor of 5-HT uptake, also in vitro." | 2.65 | Decreased uptake of 5-hydroxytryptamine in blood platelets from patients with endogenous depression. ( Ahlfors, UG; Tukiainen, E; Tuomisto, J, 1979) |
| "Amoxapine was superior to imipramine in terms of safety and usefulness." | 2.65 | Comparison of efficacy of amoxapine and imipramine in a multi-clinic double-blind study using the WHO schedule for a standard assessment of patients with depressive disorders. ( Hara, T; Kazamatsuri, H; Kurita, H; Kurokawa, H; Mori, A; Murasaki, M; Oguchi, T; Saito, Y; Sakuma, A; Sakurai, Y; Takahashi, R; Takemura, M; Yuzuriha, T, 1979) |
| " Both drugs were given in a dosage of 25 mg 3-times daily over a period of 4 weeks, and patients' progress was assessed using psychiatric and psychological rating scales for depression." | 2.65 | Amoxapine in depressive illness. ( Holden, JM; Kerry, RJ; Orme, JE, 1979) |
| " The dosage was 50 mg t." | 2.64 | Comparative clinical evaluation of lofepramine and imipramine. Psychiatric aspects. ( Borg, S; d'Elia, G; Hermann, L; Lundin, G; Perris, C; Raotma, H; Román, G; Siwers, B, 1977) |
| "A multicentre comparative clinical evaluation of lofepramine, an imipramine analogue, and imipramine has been made with double-blind technique and fixed dosage (lofepramine 70 mg t." | 2.64 | Comparative clinical evaluation of lofepramine and imipramine. Pharmacological aspects. ( Borg, S; d'Elia, G; Forshell, GP; Lundin, G; Raotma, H; Román, G; Siwers, B, 1977) |
| "Fifty-one newly hospitalized depressed patients participated in a double-blind comparison of two dosage levels of imipramine hydrochloride (150 mg vs 300 mg daily)." | 2.64 | Two dosages of imipramine in hospitalized endogenous and neurotic depressives. ( Cuculic, Z; Kellner, R; Lee, JH; Simpson, GM, 1976) |
| "Chlorpromazine was the most efficacious treatment for black women, whereas imipramine was most efficacious for black men." | 2.64 | Antidepressants in black and white inpatients. Differential response to a controlled trial of chlorpromazine and imipramine. ( Crook, TH; Raskin, A, 1975) |
| " The starting dosage was 10 mg." | 2.63 | A double-blind comparison of a new antidepressant, protryptiline, with imipramine and amitryptiline. ( Davanloo, H; Moll, A; Straker, M, 1966) |
| "Depression is a recurrent illness with high rates of chronicity, treatment-resistance and significant economic impact." | 2.53 | S-adenosyl methionine (SAMe) for depression in adults. ( Amari, E; Dougall, D; Galizia, I; Jones, TN; Lam, RW; Macritchie, K; Massei, GJ; Oldani, L; Yatham, LN; Young, AH, 2016) |
| "Depression is a common disorder that impacts on all aspects of a person's life." | 2.41 | The role of noradrenaline and selective noradrenaline reuptake inhibition in depression. ( Brunello, N; Kasper, S; Leonard, B; Mendlewicz, J; Montgomery, S; Nelson, J; Paykel, E; Racagni, G; Versiani, M, 2002) |
| "Depression is a highly prevalent concomitant of dementia." | 2.40 | Depression and dementia: comorbidities, identification, and treatment. ( Meyers, BS, 1998) |
| "Animal models of depression are important for such investigations." | 2.38 | Amygdala, depression and drug treatment. ( Fonberg, E, 1989) |
| "Ferulic acid (FA) is a common food ingredient that is abundantly present in various routinely consumed food and beverages." | 1.91 | Involvement of indoleamine 2, 3-dioxygenase (IDO) and brain-derived neurotrophic factor (BDNF) in the neuroprotective mechanisms of ferulic acid against depressive-like behaviour. ( Anoopkumar-Dukie, S; Arora, D; Grant, GD; Hall, S; Kinra, M; Mallik, SB; Mudgal, J; Nampoothiri, M; Zhang, Y, 2023) |
| "Depression is a chronic recurrent neuropsychiatric disorder associated with inflammation." | 1.72 | Methanolic Extract of ( Ahmad, FU; Arshad, HM; Lodhi, AH, 2022) |
| "The most common features of Parkinson's disease (PD) are motor impairments, but many patients also present depression and memory impairment." | 1.62 | Ketamine reversed short-term memory impairment and depressive-like behavior in animal model of Parkinson's disease. ( Andreatini, R; Da Cunha, C; Hocayen, PAS; Kanazawa, LKS; Miyoshi, E; Takahashi, RN; Vecchia, DD; Vital, MABF; Wendler, E, 2021) |
| " We examined whether these behavioral and neurochemical changes observed in OBX mice were reversed by chronic administration of imipramine." | 1.62 | Disturbance of prefrontal cortical myelination in olfactory bulbectomized mice is associated with depressive-like behavior. ( Hong, L; Kurokawa, K; Miyagawa, K; Mochida-Saito, A; Takahashi, K; Takeda, H; Tsuji, M, 2021) |
| "Imipramine was used as a reference compound, as its action is connected with mGlu5 receptor." | 1.56 | Indomethacin, a nonselective cyclooxygenase inhibitor, does not interact with MTEP in antidepressant-like activity, as opposed to imipramine in CD-1 mice. ( Stachowicz, K, 2020) |
| "Depression is common and results in a significant morbidity and economic burden." | 1.51 | The effect of depressive-like behavior and antidepressant therapy on social behavior and hierarchy in rats. ( Boyko, M; Brotfain, E; Frank, D; Frenkel, A; Grinshpun, J; Gruenbaum, BF; Gruenbaum, SE; Kutz, R; Zeldetz, V; Zlotnik, A; Zvenigorodsky, V, 2019) |
| " We also investigated the effects of dosing time on the pharmacological activity of several antidepressants acting on serotonergic, noradrenergic, and/or dopaminergic neurons." | 1.51 | Antidepressants with different mechanisms of action show different chronopharmacological profiles in the tail suspension test in mice. ( Ishibashi, T; Iwadate, R; Kawai, H; Kawashima, Y; Kudo, N; Mitsumoto, A, 2019) |
| "Depression is a serious medical condition, typically treated by antidepressants." | 1.51 | Neuronal life or death linked to depression treatment: the interplay between drugs and their stress-related outcomes relate to single or combined drug therapies. ( Badura, J; Chelminiak, Z; Cuprys, M; Fraczek, J; Koszla, O; Koziorowski, M; Mytych, J; Solek, P; Tabecka-Lonczynska, A, 2019) |
| "Depression is commonly associated with hypothalamic-pituitary adrenal (HPA) axis dysfunction that primarily manifests as aberrant glucocorticoid secretion." | 1.48 | Differential effects of imipramine and CORT118335 (Glucocorticoid receptor modulator/mineralocorticoid receptor antagonist) on brain-endocrine stress responses and depression-like behavior in female rats. ( Balmer, NJ; Caldwell, JL; Estrada, CM; Ghisays, V; Nguyen, ET; Solomon, MB; Streicher, J, 2018) |
| "Parkinson's disease is a chronic neurodegenerative disorder characterized by cardinal motor features, such as bradykinesia, but also vocal deficits (e." | 1.48 | Effects of ketamine on vocal impairment, gait changes, and anhedonia induced by bilateral 6-OHDA infusion into the substantia nigra pars compacta in rats: Therapeutic implications for Parkinson's disease. ( Andreatini, R; Bruginski, E; Campos, FR; de Almeida Soares Hocayen, P; Kanazawa, LKS; Miyoshi, E; Schwarting, RKW; Stern, CAJ; Vecchia, DD; Vital, MABF; Wendler, E; Wöhr, M, 2018) |
| "On 14th day of the treatment, depression-like behaviour was induced by LPS (0." | 1.48 | Zanthoxylum alatum abrogates lipopolysaccharide-induced depression-like behaviours in mice by modulating neuroinflammation and monoamine neurotransmitters in the hippocampus. ( Barua, CC; Haloi, P; Pathak, DC; Ren, X; Rizavi, H; Saikia, B; Sulakhiya, K; Tamuli, S, 2018) |
| " On the other hand, little is known about the impact of chronic administration of various antidepressant drugs on the brain mitochondria, as a target for the pharmacotherapy of depression." | 1.46 | Evaluation of the effectiveness of chronic antidepressant drug treatments in the hippocampal mitochondria - A proteomic study in an animal model of depression. ( Basta-Kaim, A; Budziszewska, B; Chamera, K; Głombik, K; Lasoń, W; Olszanecki, R; Ślusarczyk, J; Stachowicz, A; Suski, M; Trojan, E, 2017) |
| "A total of 32 drug-free major depressive disorder patients and 30 healthy controls were recruited." | 1.46 | Decreased Prostaglandin D2 Levels in Major Depressive Disorder Are Associated with Depression-Like Behaviors. ( Chu, C; Shen, Y; Wei, H; Xu, Q; Zhu, W, 2017) |
| "Depression is a recurrent neuropsychiatric disorder that affects millions of individuals worldwide and impact negatively on the patients' social functions and quality of life." | 1.46 | Methyl jasmonate attenuated lipopolysaccharide-induced depressive-like behaviour in mice. ( Adebesin, A; Adeoluwa, OA; Eduviere, AT; Umukoro, S, 2017) |
| "Lentinan (LNT) is an immune regulator and its potential and mechanism for the treatment of mood disorder is of our interest." | 1.46 | Lentinan produces a robust antidepressant-like effect via enhancing the prefrontal Dectin-1/AMPA receptor signaling pathway. ( Bao, H; Du, J; Du, K; Gao, T; Hou, Y; Hu, W; Li, B; Nie, J; Ran, P; Shan, L; Sun, L; Xiao, C; Zheng, B; Zheng, S; Zhu, K; Zhu, Y, 2017) |
| " The role of the α2C-AR in modulating two key depression-related behaviours in the Flinders Sensitive Line (FSL) rat was studied using a dose-response analysis following subcutaneous administration with the selective α2C-AR antagonist ORM-10921 (0." | 1.46 | The α2C-adrenoceptor antagonist, ORM-10921, exerts antidepressant-like effects in the Flinders Sensitive Line rat. ( Harvey, BH; Sallinen, J; Shahid, M; Uys, MM, 2017) |
| "Honokiol (10mg/kg) treated group depicted marked reduction in cognitive impairment and depressive-like behaviour." | 1.43 | Honokiol abrogates chronic restraint stress-induced cognitive impairment and depressive-like behaviour by blocking endoplasmic reticulum stress in the hippocampus of mice. ( Baruah, CC; Dwivedi, S; Gurjar, SS; Jangra, A; Kwatra, M; Lahkar, M; Sriram, CS; Sulakhiya, K, 2016) |
| "Depression is associated with hypothalamic-pituitary-adrenal (HPA) axis hyperactivity and testosterone exerts suppressive effects on the HPA axis." | 1.43 | Testosterone has antidepressant-like efficacy and facilitates imipramine-induced neuroplasticity in male rats exposed to chronic unpredictable stress. ( Chow, C; Galea, LA; Hamson, DK; Lieblich, SE; Tehrani, A; Wainwright, SR; Workman, JL, 2016) |
| " Therefore, we examined changes in the dopaminergic system in the caudate putamen (CPu), nucleus accumbens core (NAcC), and shell (NAcSh) of OBX mice and whether or not these alterations were reversed by chronic administration of imipramine." | 1.43 | Alterations in behavioral responses to dopamine agonists in olfactory bulbectomized mice: relationship to changes in the striatal dopaminergic system. ( Arai, Y; Hisamitsu, T; Nakagawasai, O; Nakajima, T; Nemoto, W; Takahashi, K; Tan-No, K, 2016) |
| "A growing body of evidence has focused on the impact of mitochondrial disturbances in the development of depression, but little data exist regarding the effects of chronic administration of antidepressant drugs on the brain's mitochondrial protein profile." | 1.43 | The effect of chronic tianeptine administration on the brain mitochondria: direct links with an animal model of depression. ( Basta-Kaim, A; Budziszewska, B; Głombik, K; Kubera, M; Lasoń, W; Olszanecki, R; Ślusarczyk, J; Spedding, M; Stachowicz, A; Trojan, E, 2016) |
| "Depression is a kind of mood disorder." | 1.43 | Effect of acupuncture stimulation on rats with depression induced by water-immersion stress. ( Amagasu, N; Ishida, T; Kawanoguchi, J; Mizuno, K; Takagi, K; Tanahashi, N; Wang, G; Yi, G, 2016) |
| "Depression is a common psychopathological disorders." | 1.43 | Zinc and imipramine reverse the depression-like behavior in mice induced by chronic restraint stress. ( Ding, Q; Huang, J; Li, H; Mo, F; Shen, H; Shen, Z; Tian, X; Wang, X, 2016) |
| "Although depression is the leading cause of disability worldwide, its pathophysiology is poorly understood." | 1.43 | Hippocampal Sirtuin 1 Signaling Mediates Depression-like Behavior. ( Abe-Higuchi, N; Hara, K; Higuchi, F; Hobara, T; Kobayashi, A; Uchida, S; Watanabe, Y; Yamagata, H, 2016) |
| "Depression is a major comorbidity factor of diabetes and the outcome of one disorder influences the other." | 1.43 | Evidence for the involvement of neuropeptide Y in the antidepressant effect of imipramine in type 2 diabetes. ( Bharne, AP; Kokare, DM; Nakhate, KT; Subhedar, NK; Yedke, SU, 2016) |
| "Pneumococcal meningitis is a life-threatening infection of the central nervous system (CNS) with a high mortality rate." | 1.43 | Depression-Like Adult Behaviors may be a Long-Term Result of Experimental Pneumococcal Meningitis in Wistar Rats Infants. ( Barichello, T; Dominguini, D; Generoso, JS; Jornada, LK; Quevedo, J; Sharin, VS; Simões, LR; Souza, LB; Teixeira, AL; Valvassori, SS, 2016) |
| "Dextromethorphan (DM) is an antitussive with rapid acting antidepressant potential based on pharmacodynamic similarities to ketamine." | 1.42 | Involvement of AMPA receptors in the antidepressant-like effects of dextromethorphan in mice. ( Matsumoto, RR; Nguyen, L, 2015) |
| "Ketamine is an anesthetic with antidepressant properties." | 1.42 | The positive effect on ketamine as a priming adjuvant in antidepressant treatment. ( Dalla, C; Ferreira, C; Kokras, N; Melo, A; Pêgo, JM; Sousa, N; Ventura-Silva, AP, 2015) |
| "Several non-pharmacological treatments of depression upregulate adenosine concentration and/or adenosine A1 receptors (A1R) in the brain." | 1.42 | Increased Signaling via Adenosine A1 Receptors, Sleep Deprivation, Imipramine, and Ketamine Inhibit Depressive-like Behavior via Induction of Homer1a. ( Biber, K; Clement, HW; de Bartolomeis, A; Iasevoli, F; Idzko, M; Jacobson, KA; Normann, C; Schwarz, MK; Serchov, T; Tosh, DK; van Calker, D, 2015) |
| "Plumbagin has been reported to be neuroprotective, so it might possess antidepressant activity." | 1.42 | Antidepressant-like activity of plumbagin in unstressed and stressed mice. ( Bansal, S; Dhingra, D, 2015) |
| " The present study indicates that already a moderate lesion of dopaminergic neurons induces "depressive-like" behaviour in animals which is reversed by chronic administration of the antiparkinsonian drug, pramipexole." | 1.40 | Pramipexole but not imipramine or fluoxetine reverses the "depressive-like" behaviour in a rat model of preclinical stages of Parkinson's disease. ( Berghauzen-Maciejewska, K; Dziubina, A; Głowacka, U; Kolasiewicz, W; Kuter, K; Ossowska, K; Wardas, J, 2014) |
| "Depression is one of the most prevalent mental illnesses, and causes a constant feeling of sadness and lose of interest, which often leads to suicide." | 1.40 | Disrupted MEK/ERK signaling in the medial orbital cortex and dorsal endopiriform nuclei of the prefrontal cortex in a chronic restraint stress mouse model of depression. ( Jo, SA; Kim, YH; Leem, YH; Yoon, SS, 2014) |
| " Additionally, the effects of chronic administration of the tricyclic antidepressant imipramine and the anti-TNF-α pentoxyphylline were investigated." | 1.40 | Lipopolysaccharide repeated challenge followed by chronic mild stress protocol introduces a combined model of depression in rats: reversibility by imipramine and pentoxifylline. ( Abd-Alkhalek, HA; Abdel-tawab, AM; Aboul-Fotouh, S; El Tabbal, M; Elgarf, AS; Farrag, KA; Hammouda, GA; Hassan, AN; Kassim, SK, 2014) |
| "Depression is the leading psychiatric disorder with a high risk of morbidity and mortality." | 1.40 | Chronic but not acute antidepresant treatment alters serum zinc/copper ratio under pathological/zinc-deficient conditions in mice. ( Krakowska, A; Mlyniec, K; Nowak, G; Opoka, W; Ostachowicz, B; Reczynski, W, 2014) |
| "Oxytocin is a neuromodulator with antidepressant-like effects." | 1.39 | Antidepressant-like effects of oxytocin in mice are dependent on the presence of insulin-regulated aminopeptidase. ( Chai, SY; De Bundel, D; Demaegdt, H; Gard, P; Loyens, E; Michotte, Y; Smolders, I; Vanderheyden, P, 2013) |
| "Astrocytes regulate responses to sleep deprivation, raising the possibility that glial signaling mediates antidepressive-like actions of sleep deprivation." | 1.39 | Antidepressant effects of sleep deprivation require astrocyte-dependent adenosine mediated signaling. ( Haydon, PG; Hines, DJ; Hines, RM; Moss, SJ; Schmitt, LI, 2013) |
| "Imipramine (IMIP) was used as the antidepressant reference substance." | 1.39 | Enhanced cognitive function and antidepressant-like effects after krill oil supplementation in rats. ( Berge, K; Bramham, CR; Burri, L; Duffaud, A; Messaoudi, M; Panja, D; Wibrand, K, 2013) |
| "Depression is one of the most common psychiatric diseases." | 1.39 | Antidepressant-like effects of essential oil and asarone, a major essential oil component from the rhizome of Acorus tatarinowii. ( Han, P; Han, T; Peng, W; Wang, XR, 2013) |
| " To assess the predictive validity of this behavior as a potential marker of "despair," we tested the effects of chronic administration of two common antidepressant drugs on this measure." | 1.38 | Antidepressants reduce extinction-induced withdrawal and biting behaviors: a model for depressive-like behavior. ( Huq, Y; Huston, JP; Komorowski, M; Topic, B; van den Brink, J, 2012) |
| " On the other hand, chronic administration of NAC and IMI resulted in a significant increase in cellular antioxidant mechanisms (SOD activity) that reversed the effects of BULB in the frontal cortex, hippocampus and striatum." | 1.38 | N-acetylcysteine possesses antidepressant-like activity through reduction of oxidative stress: behavioral and biochemical analyses in rats. ( Filip, M; Krzyżanowska, W; Miszkiel, J; Niedzielska, E; Ogórka, A; Pomierny, B; Pomierny-Chamioło, L; Smaga, I, 2012) |
| "In an animal model of binge drinking that exhibits abstinence-induced behaviors reminiscent of negative affective states, the triple monoamine uptake inhibitor, amitifadine, produced a selective, dose dependent attenuation of binge drinking." | 1.38 | Amitifadine, a triple monoamine uptake inhibitor, reduces binge drinking and negative affect in an animal model of co-occurring alcoholism and depression symptomatology. ( Basile, AS; June, HL; Kelly, T; Skolnick, P; Warnock, KT; Yang, AR; Yi, HS, 2012) |
| "Depression is a stress related disease, as hormones of the stress-axis can modify mood." | 1.37 | Do stress hormones connect environmental effects with behavior in the forced swim test? ( Domokos, Á; Mergl, Z; Mikics, É; Pintér, O; Zelena, D, 2011) |
| "Imipramine treatment did not affect this factor." | 1.37 | Chronic unpredictable stress-induced reduction in the hippocampal brain-derived neurotrophic factor (BDNF) gene expression is antagonized by zinc treatment. ( Cieślik, K; Legutko, B; Nowak, G; Opoka, W; Ossowska, G; Sowa-Kućma, M; Wolak, M, 2011) |
| "The treatment with imipramine reversed all the parameters described above." | 1.36 | Depressive-like parameters in sepsis survivor rats. ( Barichello, T; Cassol, OJ; Comim, CM; Constantino, LC; Constantino, LS; Dal-Pizzol, F; Kapczinski, F; Petronilho, F; Quevedo, J; Stertz, L, 2010) |
| "Imipramine treatment significantly increased the number of neurons in the granule cell layer (GCL) and spine synapses in the CA1 in the FSL imipramine group (treated "depressed" rats) compared with the FSL saline group." | 1.36 | Imipramine treatment increases the number of hippocampal synapses and neurons in a genetic animal model of depression. ( Chen, F; Madsen, TM; Nyengaard, JR; Wegener, G, 2010) |
| " When managing a patient with nonpsychotic depression and inadequate response to the maximum dose of a single antidepressant, the physician should first identify factors that may contribute to the poor response, such as suboptimal dosage resulting from nonadherence, inadequate duration of therapy, and comorbid medical and psychiatric conditions." | 1.36 | Clinical inquiries. What's best when a patient doesn't respond to the maximum dose of an antidepressant? ( Lo, V; Maggio, L, 2010) |
| " Dose-response studies using two classes of anxiolytics (chlordiazepoxide: 2." | 1.35 | Modelling the anxiety-depression continuum in chicks. ( Acevedo, EO; Huang, CJ; Sufka, KJ; Warnick, JE, 2009) |
| "Imipramine treatment reversed the UCMS-induced alterations of the coat state (BALB/c, DBA), in the NSF test (A/J, BALB/c, C57BL/6) and in fecal corticosterone metabolites (BALB/c, C57BL/6)." | 1.35 | Multifaceted strain-specific effects in a mouse model of depression and of antidepressant reversal. ( Belzung, C; Ibarguen-Vargas, Y; Palme, R; Surget, A; Touma, C, 2008) |
| "Melatonin is a hormone primarily synthesized by the pineal gland and has been shown to govern seasonal and circadian rhythms, as well as the immune system, certain behaviours, and responses to stress." | 1.35 | Antidepressant-like effects of melatonin in the mouse chronic mild stress model. ( Caumo, W; Detanico, BC; Elisabetsky, E; Freitas, JJ; Hidalgo, MP; Lhullier, FL; Piato, AL, 2009) |
| "Harmine is a beta-carboline alkaloid that inhibits monoamine reuptake systems." | 1.35 | Acute harmine administration induces antidepressive-like effects and increases BDNF levels in the rat hippocampus. ( Crippa, JA; Fortunato, JJ; Hallak, JE; Kapczinski, F; Kirsch, TR; Pinto, JP; Quevedo, J; Réus, GZ; Stertz, L; Stringari, RB; Zuardi, AW, 2009) |
| " Chronic administration of the tricyclic antidepressant imipramine (15 mg/kg, i." | 1.35 | Dopamine-dependent nature of depression-like behavior in WAG/Rij rats with genetic absence epilepsy. ( Folomkina, AA; Kulikov, MA; Midzyanovskaya, IS; Sarkisova, KY, 2008) |
| "When imipramine was suggested to be effective in depression, it was presented solely as acting in a disease specific way and it was soon referred to as an "antidepressant"." | 1.35 | The creation of the concept of an antidepressant: an historical analysis. ( Moncrieff, J, 2008) |
| " This study investigated the pharmacokinetic and pharmacological interactions between imipramine and sodium alginate in rats." | 1.35 | Pharmacokinetic and pharmacodynamic studies of drug interaction following oral administration of imipramine and sodium alginate in rats. ( Aimoto, T; Araki, H; Imai, K; Inoue, N; Suemaru, K; Watanabe, S, 2008) |
| "Major depression is a highly prevalent mental disorder and environmental factors have been strongly implicated in its pathophysiology." | 1.34 | Enriched environments influence depression-related behavior in adult mice and the survival of newborn cells in their hippocampi. ( Hashimoto, R; Hattori, S; Kunugi, H; Maeno, H; Miyakawa, T; Wada, K; Yamanaka, H, 2007) |
| "Depression is a well-defined illness that afflicts a large population worldwide." | 1.34 | Role of alpha2 receptors in quercetin-induced behavioral despair in mice. ( Chopra, K; Kaur, R; Singh, D, 2007) |
| "Imipramine treatment offset all the behavioral and neurochemical stress-induced modifications." | 1.34 | Hypothalamus-pituitary-adrenal modifications consequent to chronic stress exposure in an experimental model of depression in rats. ( Cassanelli, A; Danielli, B; De Montis, MG; Raone, A; Rauggi, R; Scheggi, S, 2007) |
| "Anxiety and depression are currently classified as separate clinical syndromes despite considerable similarities in their symptoms, pathophysiological substrates and response to treatment interventions." | 1.33 | Modeling the anxiety-depression continuum hypothesis in domestic fowl chicks. ( Acevedo, EO; Cartwright, CM; Feltenstein, MW; Sufka, KJ; Warnick, JE; Webb, HE, 2006) |
| "Depression is characterized by a lack of "motivation" rather than a lack of "physical space" to move around." | 1.32 | Open space swimming test to index antidepressant activity. ( Alkon, DL; Sun, MK, 2003) |
| "Depression is highly prevalent in diabetics and is associated with poor glucose regulation and increased risk of diabetic complications." | 1.32 | Antidepressant activity of quercetin, a bioflavonoid, in streptozotocin-induced diabetic mice. ( Anjaneyulu, M; Chopra, K; Kaur, I, 2003) |
| "Treatment with imipramine (3 x 30 mg/kg i." | 1.32 | Does rat global transient cerebral ischemia serve as an appropriate model to study emotional disturbances? ( Allain, H; Amiot, N; Bantsiele, GB; Bentué-Ferrer, D; Bourin, M; Reymann, JM, 2004) |
| "When imipramine was administered for 14 days concurrently with forced-swim stress testing, immobility was shortened significantly." | 1.32 | Influence of imipramine on the duration of immobility in chronic forced-swim-stressed rats. ( Araki, H; Gomita, Y; Kitamura, Y; Nagatani, T; Shibata, K; Takao, K, 2004) |
| " This effect can be reversed by chronic administration of various classes of antidepressant drugs." | 1.31 | The NK1-receptor antagonist NKP608 has an antidepressant-like effect in the chronic mild stress model of depression in rats. ( Gentsch, C; Papp, M; Vassout, A, 2000) |
| " On the 20th day after the start of TD feeding, the increased duration of immobility time induced by TD was shortened by chronic administration of the tricyclic antidepressant imipramine (10 mg/kg, i." | 1.31 | Characteristics of depressive behavior induced by feeding thiamine-deficient diet in mice. ( Esashi, A; Hozumi, S; Kisara, K; Nakagawasai, O; Niijima, F; Tadano, T; Tan-No, K; Taniguchi, R, 2001) |
| " Long-term administration with imipramine or mirtazapine (10 mg/kg, i." | 1.31 | Chronic treatment with imipramine or mirtazapine antagonizes stress- and FG7142-induced increase in cortical norepinephrine output in freely moving rats. ( Biggio, G; Dazzi, L; Ladu, S; Pira, L; Rivano, A; Spiga, F; Vacca, G, 2002) |
| " However, multiple dosing with either ACPC or DCS (6 daily doses, 200 mg/kg) produced an apparent behavioral adaptation, as the immobility data were indistinguishable from chronic saline administration." | 1.30 | Chronic administration of NMDA glycine partial agonists induces tolerance in the Porsolt swim test. ( Boje, KM; Lopes, T; Neubauer, P, 1997) |
| " In the present experiment, it was studied whether or not they respond to acute and chronic administration of imipramine and the possible relationship to down-regulation of beta-adrenoceptors and 5-HT1 and 5-HT2 receptors." | 1.30 | Are Wistar-Kyoto rats a genetic animal model of depression resistant to antidepressants? ( Armario, A; del Arco, C; Lahmame, A; Pazos, A; Yritia, M, 1997) |
| "Pretreatment with imipramine, MK 801 and ketamine significantly prevented the effect of shock." | 1.30 | Interaction between N-methyl-D-aspartate receptor antagonists and imipramine in shock-induced depression. ( Bapna, JS; Chandra, D; Chaturvedi, HK, 1999) |
| " Acute and chronic administration of psychotropic drugs (imipramine and chlordiazepoxide) showed that treatment with imipramine increased both the number of lever presses and successful escapes while chlordiazepoxide increased only the number of lever presses." | 1.29 | Evaluation of depression in rats exposed to chronic (unpredictable) electric shock. ( Hara, C; Naruo, T; Nozoe, S; Ogawa, N; Tanaka, H, 1993) |
| " Moreover, long term administration of both imipramine or SKF 38393 down regulated D1 dopamine receptor number in the prefrontal cortex, while the association of the two drugs resulted in a receptor density similar to that of control rats." | 1.29 | Desensitization of the D1 dopamine receptors in rats reproduces a model of escape deficit reverted by imipramine, fluoxetine and clomipramine. ( Gambarana, C; Ghiglieri, O; Graziella de Montis, M, 1995) |
| "Citalopram was inactive when given alone but it potentiated the antidepressant-like effect of MK-801." | 1.28 | Effects of MK-801 and antidepressant drugs in the forced swimming test in rats. ( Maj, J; Rogóz, Z; Skuza, G; Sowińska, H, 1992) |
| " We prospectively tested a new pharmacokinetic model that allows flexible dosing and sampling to determine maintenance requirements in patients receiving TCAs." | 1.28 | Early individualization of tricyclic antidepressant dosing using a Bayesian pharmacokinetic model. ( Harralson, AF; Hetnal, MJ; Jacisin, JJ; Kehoe, WA; Kwentus, JA; Sheffel, WB, 1991) |
| "Imipramine binding was determined on platelet membranes, using 0." | 1.28 | Circadian variation in platelet imipramine binding during the day in healthy subjects. ( Beeston, R; Cooke, RR; Ellis, PM; Mellsop, G, 1991) |
| " A relationship between age and kinetic parameters such as area under the curve, elimination phase constant, half-life and total body clearance was observed." | 1.28 | Imipramine pharmacokinetics in depressed geriatric patients. ( Baraldo, M; Benetello, P; Furlanut, M; Zara, G, 1990) |
| " These results are consistent with either a decrease in oral bioavailability of IMI in alcoholics or, assuming complete absorption, an increase in intrinsic clearance of 2." | 1.26 | Imipramine disposition in alcoholics. ( Alderson, LM; Chapron, DJ; Ciraulo, DA; Jaffe, JH; Kramer, PA; Subbarao, B, 1982) |
| "The authors describe 2 cases in which withdrawal symptoms occurred during the course of imipramine therapy, after the patients had failed to take a single daily dose of medication." | 1.26 | Withdrawal symptoms during the course of imipramine therapy. ( Mendels, J; Stern, SL, 1980) |
| "In our experience orthostatic hypotension is the commonest serious cardiovascular side-effect of imipramine." | 1.26 | Clinical characteristics of imipramine-induced orthostatic hypotension. ( Bigger, JT; Davies, M; Giardina, EV; Glassman, AH; Kantor, SJ; Perel, JM, 1979) |
| "The prevalence of atherosclerotic impotence is not known but may be relatively high in older men." | 1.26 | Impotence responsive to glyceryl trinitrate. ( Mudd, JW, 1977) |
| "Tricyclic antidepressant plasma levels were measured in patients and healthy subjects after a single dise of desmethylimipramine (DMI) or imipramine (IMI) and after chronic dosing to steady states." | 1.26 | Prediction of steady-state imipramine and desmethylimipramine plasma concentrations from single-dose data. ( Amsterdam, JD; Brunswick, DJ; Mendels, J; Stern, SL, 1979) |
| "Nomifensine is a tetrahydoisoquinoline antidepressant which is chemically unrelated to the tricyclic or tetracyclic antidepressants, the monoamine oxidase inhibitors or the recently introduced agents." | 1.26 | Nomifensine: A review of its pharmacological properties and therapeutic efficacy in depressive illness. ( Avery, GS; Brogden, RN; Heel, RC; Speight, TM, 1979) |
| "Dental Caries are an uncommon, but significant side effect of the tricyclic antidepressants and other anticholinergic psychoactive drugs." | 1.26 | Rampant dental caries in the treatment of depression. ( Bassuk, E; Schoonover, S, 1978) |
| "They feel that the orthostatic hypotension seen in all seven patients represents a potentially serious problem with tricyclic antidepressants." | 1.26 | The cardiac effects of therapeutic plasma concentrations of imipramine. ( Bigger, JT; Giardina, EV; Glassman, AH; Kantor, SJ; Perel, JM, 1978) |
| " Plasma levels of the tricyclics were relatively stable on both dosage schedules due to the long plasma half-lives of these drugs." | 1.26 | Imipramine and desipramine plasma levels: relationship to dosage schedule and sampling time. ( Biggs, JT; Meyer, DA; Preskorn, SH; Rosen, SH; Ziegler, VE, 1978) |
| "In imipramine-treated patients this finding was associated with a decreased rate of drug elimination from plasma." | 1.26 | Relationship between age and tricyclic antidepressant plasma levels. ( Cooper, TB; Friedman, MJ; Green, R; Ives, JO; Nies, A; Ravaris, CL; Robinson, DS, 1977) |
| " No systemic changes of heart frequency and blood pressure were found during the infusions in spite of the high dosage of tricyclic antidepressants given such a short period as 1 hour." | 1.26 | Investigation of the orthostatic reaction after intravenous administration of imipramine, chlorimipramine, and inimpramine-N-oxide. ( Bake, B; Dencker, SJ, 1976) |
| "Depression is among the most common of clinical conditions." | 1.25 | Managing depression in the '70s. ( Bowden, CL, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 995 (71.84) | 18.7374 |
| 1990's | 80 (5.78) | 18.2507 |
| 2000's | 124 (8.95) | 29.6817 |
| 2010's | 160 (11.55) | 24.3611 |
| 2020's | 26 (1.88) | 2.80 |
| Authors | Studies |
|---|---|
| McCarthy, JR | 1 |
| Wright, DL | 1 |
| Schuster, AJ | 1 |
| Abdallah, AH | 1 |
| Shea, PJ | 1 |
| Eyster, R | 1 |
| Duarte, FS | 2 |
| Codeço Martins, PR | 1 |
| Romeiro, GA | 1 |
| Monteiro De Lima, TC | 1 |
| Balavoine, F | 1 |
| Malabre, P | 1 |
| Alleaume, T | 1 |
| Rey, A | 1 |
| Cherfils, V | 1 |
| Jeanneton, O | 1 |
| Seigneurin-Venin, S | 1 |
| Revah, F | 1 |
| Bojarski, AJ | 1 |
| Kuran, B | 1 |
| Kossakowski, J | 1 |
| Kozioł, A | 1 |
| Jagiełło-Wójtowicz, E | 1 |
| Chodkowska, A | 1 |
| Lewellyn, K | 1 |
| Bialonska, D | 1 |
| Loria, MJ | 1 |
| White, SW | 1 |
| Sufka, KJ | 5 |
| Zjawiony, JK | 1 |
| Sashidhara, KV | 1 |
| Modukuri, RK | 1 |
| Singh, S | 4 |
| Bhaskara Rao, K | 1 |
| Aruna Teja, G | 1 |
| Gupta, S | 2 |
| Shukla, S | 2 |
| Hirose, W | 1 |
| Kato, Y | 1 |
| Yamamoto, T | 1 |
| Kassai, M | 1 |
| Takata, M | 1 |
| Hayashi, S | 1 |
| Arai, Y | 2 |
| Imai, S | 2 |
| Yoshida, K | 1 |
| Pandey, D | 1 |
| Mandalapu, D | 1 |
| Sharma, V | 1 |
| Shukla, M | 1 |
| Singh, N | 1 |
| Yadav, SK | 1 |
| Tanpula, DK | 1 |
| Maikhuri, JP | 1 |
| Lal, J | 1 |
| Siddiqi, MI | 1 |
| Gupta, G | 1 |
| Sharma, VL | 1 |
| Czopek, A | 1 |
| Bucki, A | 1 |
| Kołaczkowski, M | 1 |
| Zagórska, A | 1 |
| Drop, M | 1 |
| Pawłowski, M | 1 |
| Siwek, A | 1 |
| Głuch-Lutwin, M | 1 |
| Pękala, E | 1 |
| Chrzanowska, A | 1 |
| Struga, M | 1 |
| Partyka, A | 1 |
| Wesołowska, A | 4 |
| Nirogi, R | 1 |
| Mohammed, AR | 1 |
| Shinde, AK | 1 |
| Ravella, SR | 1 |
| Bogaraju, N | 1 |
| Subramanian, R | 1 |
| Mekala, VR | 1 |
| Palacharla, RC | 1 |
| Muddana, N | 1 |
| Thentu, JB | 1 |
| Bhyrapuneni, G | 1 |
| Abraham, R | 1 |
| Jasti, V | 1 |
| Malhotra, V | 1 |
| Vats, M | 1 |
| Nath, R | 1 |
| Mehta, S | 1 |
| Kumar, R | 1 |
| Bhalla, M | 1 |
| Sinha, JN | 1 |
| Shanker, K | 1 |
| Pathak, SR | 1 |
| Bhatt, S | 1 |
| Behl, T | 1 |
| Sehgal, A | 1 |
| Sharma, N | 1 |
| Chigurupati, S | 1 |
| Ahmed, AS | 1 |
| Gari, SBV | 1 |
| Baethge, C | 1 |
| Braun, C | 1 |
| Rink, L | 1 |
| Schwarzer, G | 1 |
| Henssler, J | 1 |
| Bschor, T | 1 |
| Shamabadi, A | 1 |
| Silveira, KM | 1 |
| Sartim, AG | 1 |
| Vieira, L | 1 |
| Lisboa, SF | 2 |
| Wegener, G | 6 |
| Joca, SRL | 2 |
| Arshad, HM | 2 |
| Ahmad, FU | 2 |
| Lodhi, AH | 2 |
| Kukuia, KKE | 1 |
| Burns, FB | 1 |
| Adutwum-Ofosu, KK | 1 |
| Appiah, F | 1 |
| Amponsah, SK | 1 |
| Begyinah, R | 1 |
| Koomson, AE | 1 |
| Ferka, YT | 1 |
| Tagoe, TA | 1 |
| Amoateng, P | 1 |
| Rao, Y | 1 |
| Yang, R | 1 |
| Zhao, J | 2 |
| Cao, Q | 1 |
| Önel, T | 1 |
| Arıcıoğlu, F | 3 |
| Yıldırım, E | 1 |
| Zortul, H | 1 |
| Yaba, A | 1 |
| Mallik, SB | 1 |
| Mudgal, J | 1 |
| Kinra, M | 1 |
| Hall, S | 1 |
| Grant, GD | 1 |
| Anoopkumar-Dukie, S | 1 |
| Nampoothiri, M | 1 |
| Zhang, Y | 2 |
| Arora, D | 1 |
| Soytürk, H | 1 |
| Bozat, BG | 1 |
| Pehlivan Karakas, F | 1 |
| Coskun, H | 1 |
| Firat, T | 1 |
| Rodrigues, ACC | 1 |
| Moreira, CVL | 1 |
| Prado, CC | 1 |
| Silva, LSB | 1 |
| Costa, RF | 1 |
| Arikawe, AP | 1 |
| Pedrino, GR | 1 |
| Costa, EA | 2 |
| Silva, ON | 1 |
| Napolitano, HB | 1 |
| Oliveira-Silva, I | 1 |
| Fajemiroye, JO | 1 |
| Huang, Y | 1 |
| Xu, D | 1 |
| Xiang, H | 1 |
| Yan, S | 1 |
| Sun, F | 1 |
| Wei, Z | 1 |
| Sell, SL | 1 |
| Boone, DR | 1 |
| Weisz, HA | 1 |
| Cardenas, C | 1 |
| Willey, HE | 1 |
| Bolding, IJ | 1 |
| Micci, MA | 1 |
| Falduto, MT | 1 |
| Torres, KEO | 1 |
| DeWitt, DS | 1 |
| Prough, DS | 1 |
| Hellmich, HL | 1 |
| Tung, TH | 1 |
| Tung, YT | 1 |
| Lin, IH | 1 |
| Shih, CK | 1 |
| Nguyen, NTK | 1 |
| Shabrina, A | 1 |
| Huang, SY | 1 |
| Schelder-Marzzani, SH | 1 |
| Dias, P | 1 |
| Freiberger, V | 1 |
| Ventura, L | 1 |
| Silva, BB | 1 |
| Dutra, ML | 1 |
| Bobinski, F | 1 |
| Schlindwein, AD | 1 |
| Cassol, OJ | 2 |
| Comim, CM | 4 |
| Zadeh-Ardabili, PM | 1 |
| Rad, SK | 2 |
| Movafagh, A | 1 |
| Pavlov, D | 2 |
| Gorlova, A | 1 |
| Bettendorff, L | 2 |
| Kalueff, AA | 1 |
| Umriukhin, A | 1 |
| Proshin, A | 1 |
| Lysko, A | 1 |
| Landgraf, R | 1 |
| Anthony, DC | 1 |
| Strekalova, T | 3 |
| Wang, Y | 2 |
| He, W | 1 |
| Zhang, H | 3 |
| Yao, Z | 1 |
| Che, F | 1 |
| Cao, Y | 1 |
| Sun, H | 1 |
| Wang, YJ | 1 |
| Liu, L | 1 |
| Wang, JL | 1 |
| Gao, TT | 1 |
| Wang, H | 1 |
| Chen, TT | 1 |
| Guan, W | 1 |
| Jiang, B | 1 |
| Stachowicz, K | 4 |
| Xiang, L | 1 |
| Feng, Y | 1 |
| Hu, Q | 1 |
| Zhu, J | 1 |
| Ye, R | 1 |
| Yuan, Z | 1 |
| Sun, L | 2 |
| Verkaik-Schakel, RN | 1 |
| Biber, K | 2 |
| Plösch, T | 1 |
| Serchov, T | 2 |
| Vecchia, DD | 2 |
| Kanazawa, LKS | 2 |
| Wendler, E | 2 |
| Hocayen, PAS | 1 |
| Vital, MABF | 2 |
| Takahashi, RN | 1 |
| Da Cunha, C | 1 |
| Miyoshi, E | 2 |
| Andreatini, R | 3 |
| Reddy, BR | 1 |
| Babu, NS | 1 |
| Das, T | 1 |
| Bhattacharya, D | 1 |
| Murthy, CLN | 1 |
| Kumar, A | 3 |
| Idris, MM | 1 |
| Chakravarty, S | 1 |
| Campos-Cardoso, R | 1 |
| Silva, CPB | 1 |
| Carolino, ROG | 1 |
| Anselmo-Franci, JA | 1 |
| Tirapelli, CR | 1 |
| Padovan, CM | 1 |
| Chmielarz, P | 1 |
| Kuśmierczyk, J | 1 |
| Rafa-Zabłocka, K | 1 |
| Chorązka, K | 1 |
| Kowalska, M | 1 |
| Satała, G | 1 |
| Nalepa, I | 2 |
| Takahashi, K | 4 |
| Kurokawa, K | 1 |
| Hong, L | 1 |
| Miyagawa, K | 1 |
| Mochida-Saito, A | 1 |
| Takeda, H | 1 |
| Tsuji, M | 1 |
| Khakpai, F | 1 |
| Ramezanikhah, M | 1 |
| Valizadegan, F | 1 |
| Zarrindast, MR | 1 |
| Zhang, L | 2 |
| Tang, M | 1 |
| Xie, X | 1 |
| Zhao, Q | 1 |
| Hu, N | 1 |
| He, H | 1 |
| Liu, G | 1 |
| Huang, S | 1 |
| Peng, C | 1 |
| Xiao, Y | 1 |
| You, Z | 1 |
| Faron-Górecka, A | 2 |
| Kuśmider, M | 2 |
| Szafran-Pilch, K | 1 |
| Kolasa, M | 2 |
| Żurawek, D | 2 |
| Gruca, P | 5 |
| Papp, M | 15 |
| Solich, J | 2 |
| Pabian, P | 2 |
| Dziedzicka-Wasylewska, M | 2 |
| Możdżeń, E | 1 |
| Wąsik, A | 1 |
| Romańska, I | 2 |
| Michaluk, J | 1 |
| Antkiewicz-Michaluk, L | 2 |
| Getachew, B | 2 |
| Hauser, SR | 2 |
| Csoka, AB | 1 |
| Taylor, RE | 2 |
| Tizabi, Y | 2 |
| Głombik, K | 3 |
| Stachowicz, A | 3 |
| Trojan, E | 4 |
| Olszanecki, R | 3 |
| Ślusarczyk, J | 3 |
| Suski, M | 2 |
| Chamera, K | 2 |
| Budziszewska, B | 3 |
| Lasoń, W | 3 |
| Basta-Kaim, A | 5 |
| Chu, C | 1 |
| Wei, H | 1 |
| Zhu, W | 1 |
| Shen, Y | 1 |
| Xu, Q | 1 |
| Undurraga, J | 1 |
| Baldessarini, RJ | 1 |
| Adebesin, A | 1 |
| Adeoluwa, OA | 1 |
| Eduviere, AT | 1 |
| Umukoro, S | 1 |
| Mustafa, FA | 1 |
| Carey, LM | 1 |
| Rice, RJ | 1 |
| Prus, AJ | 1 |
| Muñoz-Cobo, I | 1 |
| Belloch, FB | 1 |
| Díaz-Perdigón, T | 1 |
| Puerta, E | 1 |
| Tordera, RM | 1 |
| Markova, N | 1 |
| Chekhonin, V | 1 |
| Pomytkin, I | 1 |
| Lioudyno, V | 1 |
| Svistunov, A | 1 |
| Ponomarev, E | 1 |
| Lesch, KP | 1 |
| Nguyen, ET | 2 |
| Caldwell, JL | 2 |
| Streicher, J | 2 |
| Ghisays, V | 2 |
| Balmer, NJ | 1 |
| Estrada, CM | 2 |
| Solomon, MB | 2 |
| da Cruz, KR | 1 |
| Turones, LC | 1 |
| Camargo-Silva, G | 1 |
| Gomes, KP | 1 |
| Mendonça, MM | 1 |
| Galdino, P | 1 |
| Rodrigues-Silva, C | 1 |
| Santos, RAS | 1 |
| Ghedini, PC | 1 |
| Ianzer, D | 1 |
| Xavier, CH | 1 |
| Oberholzer, I | 1 |
| Möller, M | 1 |
| Holland, B | 1 |
| Dean, OM | 1 |
| Berk, M | 2 |
| Harvey, BH | 2 |
| Stanquini, LA | 1 |
| Biojone, C | 4 |
| Guimarães, FS | 4 |
| Joca, SR | 4 |
| Menard, C | 1 |
| Pfau, ML | 1 |
| Hodes, GE | 1 |
| Kana, V | 1 |
| Wang, VX | 1 |
| Bouchard, S | 1 |
| Takahashi, A | 1 |
| Flanigan, ME | 1 |
| Aleyasin, H | 1 |
| LeClair, KB | 1 |
| Janssen, WG | 1 |
| Labonté, B | 1 |
| Parise, EM | 1 |
| Lorsch, ZS | 1 |
| Golden, SA | 1 |
| Heshmati, M | 1 |
| Tamminga, C | 1 |
| Turecki, G | 1 |
| Campbell, M | 1 |
| Fayad, ZA | 1 |
| Tang, CY | 1 |
| Merad, M | 1 |
| Russo, SJ | 2 |
| Riga, D | 1 |
| Kramvis, I | 1 |
| Koskinen, MK | 1 |
| van Bokhoven, P | 1 |
| van der Harst, JE | 1 |
| Heistek, TS | 1 |
| Jaap Timmerman, A | 1 |
| van Nierop, P | 1 |
| van der Schors, RC | 1 |
| Pieneman, AW | 1 |
| de Weger, A | 1 |
| van Mourik, Y | 1 |
| Schoffelmeer, ANM | 1 |
| Mansvelder, HD | 1 |
| Meredith, RM | 1 |
| Hoogendijk, WJG | 1 |
| Smit, AB | 1 |
| Spijker, S | 1 |
| Abreu, TM | 1 |
| Monteiro, VS | 1 |
| Martins, ABS | 1 |
| Teles, FB | 1 |
| da Conceição Rivanor, RL | 1 |
| Mota, ÉF | 1 |
| Macedo, DS | 1 |
| de Vasconcelos, SMM | 1 |
| Júnior, JERH | 1 |
| Benevides, NMB | 1 |
| de Almeida Soares Hocayen, P | 1 |
| Bruginski, E | 1 |
| Campos, FR | 1 |
| Stern, CAJ | 1 |
| Wöhr, M | 1 |
| Schwarting, RKW | 1 |
| Kotarska, K | 1 |
| Barua, CC | 1 |
| Haloi, P | 1 |
| Saikia, B | 1 |
| Sulakhiya, K | 2 |
| Pathak, DC | 1 |
| Tamuli, S | 1 |
| Rizavi, H | 1 |
| Ren, X | 1 |
| Szlachta, M | 1 |
| Szopa, A | 2 |
| Poleszak, E | 6 |
| Bogatko, K | 1 |
| Wyska, E | 2 |
| Wośko, S | 3 |
| Doboszewska, U | 1 |
| Świąder, K | 2 |
| Wlaź, A | 2 |
| Dudka, J | 2 |
| Wróbel, A | 5 |
| Wlaź, P | 5 |
| Serefko, A | 6 |
| Willner, P | 3 |
| Lason, M | 1 |
| Tota-Glowczyk, K | 1 |
| Litwa, E | 1 |
| Niemczyk, M | 1 |
| Simões, LR | 2 |
| Netto, S | 1 |
| Generoso, JS | 2 |
| Ceretta, RA | 1 |
| Valim, RF | 1 |
| Dominguini, D | 2 |
| Michels, M | 1 |
| Réus, GZ | 3 |
| Valvassori, SS | 3 |
| Dal-Pizzol, F | 3 |
| Barichello, T | 3 |
| Starowicz, G | 1 |
| Jarosz, M | 1 |
| Frąckiewicz, E | 1 |
| Grzechnik, N | 1 |
| Ostachowicz, B | 2 |
| Nowak, G | 8 |
| Mlyniec, K | 2 |
| Tillmann, S | 1 |
| Happ, DF | 1 |
| Mikkelsen, PF | 1 |
| Geisel, J | 1 |
| Obeid, R | 1 |
| de la Garza, AL | 1 |
| Garza-Cuellar, MA | 1 |
| Silva-Hernandez, IA | 1 |
| Cardenas-Perez, RE | 1 |
| Reyes-Castro, LA | 1 |
| Zambrano, E | 1 |
| Gonzalez-Hernandez, B | 1 |
| Garza-Ocañas, L | 1 |
| Fuentes-Mera, L | 1 |
| Camacho, A | 1 |
| Walker, AJ | 2 |
| Price, JB | 1 |
| Borreggine, K | 1 |
| Sutor, SL | 1 |
| Gogos, A | 1 |
| McGillivray, JA | 1 |
| Frye, MA | 1 |
| Tye, SJ | 2 |
| Herbst, LS | 1 |
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| Sabbot, IM | 1 |
| Meyer, R | 1 |
| Vaillant, GE | 1 |
| Serry, D | 1 |
| Serry, M | 1 |
| Steven, L | 1 |
| Pope, RA | 1 |
| Stoianov, S | 1 |
| Antonov, L | 1 |
| Goldstein, RL | 1 |
| Hildebrandt, HJ | 1 |
| Willcox, DR | 1 |
| Gillan, R | 1 |
| Fragoso Mendes, J | 1 |
| Lopes Da Silva, F | 1 |
| Imlah, NW | 1 |
| Fahy, PT | 1 |
| Harrington, JA | 1 |
| McNair, FE | 1 |
| Lafave, HG | 1 |
| March, BW | 1 |
| Kargas, AK | 1 |
| Shuffler, SY | 1 |
| Burns, BH | 1 |
| Wolffenbüttel, P | 1 |
| Westman, M | 1 |
| Sargant, W | 1 |
| Wright, N | 1 |
| Sigwald, J | 1 |
| Raymondeaud, C | 1 |
| Shatan, C | 1 |
| Baldridge, W | 1 |
| Grabowsky, JR | 1 |
| Christe, P | 1 |
| Hudgens, RW | 1 |
| Tanna, VL | 1 |
| Harley, JD | 1 |
| Leary, DJ | 1 |
| Lowinger, P | 1 |
| Dobie, S | 1 |
| Cwynar, S | 2 |
| Napieralska, N | 2 |
| Posel, Z | 2 |
| Siuchnińska, H | 2 |
| Wojdyslawska, I | 2 |
| Bilikiewicz, A | 1 |
| Pohlmeier, H | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Acute and Chronic Impacts of Muscadine Wine Polyphenols on Cognition, Memory, Mood, and Anxiety in Adults Over 50 Years of Age[NCT05541887] | 25 participants (Anticipated) | Interventional | 2023-08-30 | Recruiting | |||
| Does a GLP-1 Receptor Agonist Change Glucose Tolerance in Antipsychotic-treated Patients? A Randomized, Double-blinded, Placebo-controlled Clinical Trial[NCT01845259] | Phase 2 | 103 participants (Actual) | Interventional | 2013-04-30 | Active, not recruiting | ||
| The Role of Negr1 In Modulating Neuroplasticity in Major Depression (RONIN)[NCT06131268] | Phase 4 | 30 participants (Anticipated) | Interventional | 2022-03-01 | Recruiting | ||
| Whole-Body Hyperthermia for Mood and Anxiety Disorders[NCT06144294] | 240 participants (Anticipated) | Interventional | 2024-01-31 | Not yet recruiting | |||
| The Treatment Efficacy of Combination Atypical Antipsychotics With Sertraline in Patients With Schizophrenia[NCT04076371] | 1,640 participants (Actual) | Interventional | 2012-01-31 | Completed | |||
| Effects of Intraoperative Low-dose Ketamine on Incidence of Postpartum Depression in Parturients With Prenatal Depression Undergoing Cesarean Delivery: Blind Test, Randomized, Placebo-controlled Trial[NCT03336541] | Phase 4 | 64 participants (Actual) | Interventional | 2017-11-23 | Completed | ||
| A Randomized Double-Blind Pilot Study of Memantine Augmentation in Antidepressant Nonresponders or Incomplete Responders[NCT00344682] | Phase 4 | 31 participants (Actual) | Interventional | 2006-06-30 | Completed | ||
| [NCT00000369] | Phase 3 | 0 participants | Interventional | 1997-06-30 | Completed | ||
| A Comparative Trial of TMS Approaches to Treating Depression[NCT01906905] | Phase 4 | 0 participants (Actual) | Interventional | 2013-06-30 | Withdrawn | ||
| Cerebral Neuroinflammation During Major Depressive Episode: Multicentric Comparative Study.[NCT03314155] | 60 participants (Anticipated) | Interventional | 2018-12-07 | Recruiting | |||
| Adjunctive Triple Chronotherapy in the Acute Treatment of Depression and Suicidality in the Adolescent Population: A Randomized Controlled Trial[NCT03679962] | 64 participants (Actual) | Interventional | 2019-01-25 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Each item is scored on a scale of 0 (not present) to 4 (severe), with a total score range of 0-56, where <17 indicates mild severity, 18-24 mild to moderate severity and 25-30 moderate to severe. Scores > 30 indicate severe anxiety. (NCT00344682)
Timeframe: baseline & week 8
| Intervention | units on a scale (Mean) |
|---|---|
| Placebo | -4.13 |
| Memantine | -5.53 |
The 16 item Quick Inventory of Depressive Symptomatology (QIDS-SR16) (Rush et al. 2003) is designed to assess the severity of depressive symptoms, with higher scores representing more severe forms of depression. When complete, the QIDS are scored by summing responses to obtain a total score ranging from 0 to 27. Either appetite increase or decrease, but not both, are used to calculate the total score. Weight increase or decrease, but not both, are used to calculate the total score. Scores 0-5 indicate no severity of depression; 6-10 is mild; 11-15 is moderate; 16-20 is severe; 21-27 is very severe levels of depression. Participants were evaluated at baseline and at weeks 1, 2, 3, 4, 6 & 8. (NCT00344682)
Timeframe: baseline & week 8
| Intervention | units on a scale (Mean) |
|---|---|
| Placebo | -3.69 |
| Memantine | -6.47 |
Higher MADRS score indicates more severe depression, and each item yields a score of 0 to 6 on 10 items. The overall score ranges from 0 to 60. Scores 0 to 6 indicate symptoms absent; 7 to 19 indicates mild depression; 30 to 34 defines moderate; 35 to 60 indicates severe depression. Changes in response rate and remission rate were assessed for secondary measures. (NCT00344682)
Timeframe: baseline and week 8
| Intervention | units on a scale (Mean) |
|---|---|
| Placebo | -10.75 |
| Memantine | -7.13 |
Higher MADRS score indicates more severe depression, and each item yields a score of 0 to 6. The overall score ranges from 0 to 60. Scores 0 to 6 indicate symptoms absent; 7 to 19 indicates mild depression; 30 to 34 defines moderate; 35 to 60 indicates severe depression. Changes in MADRS score was a primary measure. (NCT00344682)
Timeframe: Baseline & week 8
| Intervention | units on a scale (Mean) |
|---|---|
| Placebo | -7.25 |
| Memantine | -7.13 |
76 reviews available for imipramine and Depression
| Article | Year |
|---|---|
Dose effects of tricyclic antidepressants in the treatment of acute depression - A systematic review and meta-analysis of randomized trials.
Topics: Antidepressive Agents; Antidepressive Agents, Tricyclic; Depression; Humans; Imipramine; Randomized | 2022 |
Topiramate and other kainate receptor antagonists for depression: A systematic review of randomized controlled trials.
Topics: Depression; Humans; Imipramine; Phenobarbital; Quality of Life; Randomized Controlled Trials as Topi | 2022 |
Efficacy and tolerability of antidepressant drugs in treatment of depression in children and adolescents: a network meta-analysis.
Topics: Adolescent; Amitriptyline; Antidepressive Agents; Child; Depression; Depressive Disorder, Major; Dul | 2022 |
Direct comparison of tricyclic and serotonin-reuptake inhibitor antidepressants in randomized head-to-head trials in acute major depression: Systematic review and meta-analysis.
Topics: Antidepressive Agents, Tricyclic; Depression; Depressive Disorder, Major; Double-Blind Method; Human | 2017 |
S-adenosyl methionine (SAMe) for depression in adults.
Topics: Adult; Aged; Aged, 80 and over; Antidepressive Agents; Citalopram; Depression; Humans; Imipramine; M | 2016 |
[Antidepressants in migraine prophylaxis].
Topics: Amitriptyline; Antidepressive Agents; Clinical Trials as Topic; Depression; Drug Administration Sche | 2009 |
Magnesium for treatment-resistant depression: a review and hypothesis.
Topics: Animals; Antidepressive Agents, Tricyclic; Brain; Clinical Trials as Topic; D-Aspartic Acid; Depress | 2010 |
The role of noradrenaline and selective noradrenaline reuptake inhibition in depression.
Topics: Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents; Catechol O-Methyltransferase; Depressi | 2002 |
CURRENT STATUS OF DRUG TREATMENT IN THE DEPRESSIVE STATE.
Topics: Amitriptyline; Amphetamine; Amphetamines; Antidepressive Agents; Aspartic Acid; Benactyzine; Classif | 1964 |
[5 YEARS OF DRUG THERAPY OF DEPRESSIVE STATES WITH IMINODIBENZYL DERIVATIVES].
Topics: Benzylamines; Depression; Depressive Disorder; Diabetes Mellitus; Electroconvulsive Therapy; Epileps | 1964 |
THE PHARMACOTHERAPY OF THE DEPRESSIVE SYNDROME.
Topics: Amitriptyline; Antidepressive Agents; Convulsive Therapy; Depression; Depressive Disorder; Desiprami | 1965 |
THE ANTIDEPRESSANT DRUGS.
Topics: Amitriptyline; Antidepressive Agents; Central Nervous System Stimulants; Depression; Depressive Diso | 1965 |
The interaction of psychopharmacology and psychoanalysis in the borderline patient.
Topics: Affect; Anger; Antipsychotic Agents; Borderline Personality Disorder; Chlorpromazine; Clinical Trial | 1980 |
Current concepts of the mechanisms of action of antidepressant drugs.
Topics: Adenylyl Cyclases; Animals; Antidepressive Agents; Behavior, Animal; Binding Sites; Biogenic Amines; | 1981 |
Autacoids for drug receptors: a new approach in drug development.
Topics: Adenylyl Cyclases; Animals; Brain Chemistry; Carbolines; Carrier Proteins; Chemical Phenomena; Chemi | 1984 |
[The state of psychopharmacotherapy in geriatrics 2].
Topics: Actihaemyl; Aged; Amitriptyline; Bencyclane; Cerebrovascular Circulation; Clorazepate Dipotassium; D | 1980 |
The efficacy of amoxapine, maprotiline, and trazodone in comparison to imipramine and amitriptyline: a review of the literature.
Topics: Amitriptyline; Amoxapine; Anthracenes; Clinical Trials as Topic; Depression; Dibenzoxazepines; Human | 1984 |
Current concepts. Electroconvulsive therapy--a current perspective.
Topics: Depression; Electroconvulsive Therapy; Humans; Imipramine; Memory Disorders; Methods; Patient Accept | 1984 |
The clinical application of tricyclic antidepressant pharmacokinetics and plasma levels.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Depression; Desipramine; Doxepin; Heart; Humans; Im | 1980 |
Pharmacokinetics and clinical response to tricyclic antidepressants.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Clinical Trials as Topic; Depression; Humans; Imipr | 1980 |
Measurement of serum drug levels in the assessment of antidepressants.
Topics: Amitriptyline; Antidepressive Agents; Depression; Humans; Imipramine; Nortriptyline | 1980 |
Cardiovascular effects of tricyclic antidepressant drugs: therapeutic usage, overdose, and management of complications.
Topics: Adult; Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Cardiovascular S | 1982 |
High-affinity binding of 3H-imipramine in brain and platelets: relevance to depression and antidepressant drugs.
Topics: Animals; Antidepressive Agents; Blood Platelets; Brain; Carrier Proteins; Depression; Humans; Imipra | 1982 |
Trazodone--a new type of antidepressant: a discussion of pharmacological data and their clinical implications.
Topics: Animals; Brain; Depression; Humans; Imipramine; Piperazines; Receptors, Serotonin; Trazodone | 1982 |
Imipramine-induced hyperpigmentation: four cases and a review of the literature.
Topics: Aged; Antidepressive Agents, Tricyclic; Depression; Female; Humans; Hyperpigmentation; Imipramine; M | 1999 |
Depression and dementia: comorbidities, identification, and treatment.
Topics: Aged; Aged, 80 and over; Antidepressive Agents, Tricyclic; Benzamides; Citalopram; Clomipramine; Cog | 1998 |
Hypericum for depression. An update of the clinical evidence.
Topics: Amitriptyline; Antidepressive Agents; Depression; Humans; Hypericum; Imipramine; Phytotherapy; Plant | 1999 |
Gender differences in depression associated with neurologic illness: clinical correlates and pharmacologic response.
Topics: Alzheimer Disease; Amitriptyline; Antidepressive Agents, Tricyclic; Depression; Epilepsy; Female; Hu | 2001 |
Efficacy and tolerability of Ze 117 St. John's wort extract in comparison with placebo, imipramine and fluoxetine for the treatment of mild to moderate depression according to ICD-10. An overview.
Topics: Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; D | 2001 |
Clinical and biochemical heterogeneity of depressive disorders.
Topics: Amitriptyline; Animals; Antidepressive Agents; Brain; Depression; Desipramine; Dextroamphetamine; Em | 1978 |
Tricyclic antidepressants (first of two parts).
Topics: Aged; Amines; Amitriptyline; Antidepressive Agents, Tricyclic; Chemical Phenomena; Chemistry; Child; | 1978 |
Doxepin up-to-date: a review of its pharmacological properties and therapeutic efficacy with particular reference to depression.
Topics: Alcoholism; Amitriptyline; Animals; Anxiety; Cardiovascular Diseases; Depression; Doxepin; Drug Inte | 1977 |
Efficacy of ECT in affective and schizophrenic illness.
Topics: Amitriptyline; Chlorpromazine; Depression; Electroconvulsive Therapy; Evaluation Studies as Topic; H | 1977 |
A review of controlled studies with nomifensine, performed outside the UK.
Topics: Adult; Aged; Amitriptyline; Clinical Trials as Topic; Depression; Double-Blind Method; Doxepin; Drug | 1977 |
Review of the pharmacology of existing antidepressants.
Topics: Amphetamine; Animals; Antidepressive Agents; Brain; Catecholamines; Depression; Humans; Imipramine; | 1977 |
Blood levels of tricyclic antidepressant drugs: assay procedures, reproducibility and relationship to therapeutic outcome and side effects.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Clinical Trials as Topic; Depression; Double-Blind | 1977 |
Mianserin: a review of its pharmacological properties and therapeutic efficacy in depressive illness.
Topics: Amitriptyline; Animals; Antidepressive Agents; Carbohydrate Metabolism; Cardiovascular Diseases; Dep | 1978 |
[Treatment of psychiatric disorders in the aged].
Topics: Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Bipolar Disorder; Depression; Electroconvulsi | 1978 |
Long-term maintenance drug therapy in recurrent affective illness: current status and issues.
Topics: Affective Symptoms; Antidepressive Agents, Tricyclic; Bipolar Disorder; Depression; Drug Evaluation; | 1977 |
Thyroid hormone in the treatment of depression.
Topics: Depression; Drug Therapy, Combination; Electroconvulsive Therapy; Humans; Imipramine; Injections, In | 1975 |
The possible role of thyroid and thyrotrophic hormones in depressive illness.
Topics: Depression; Electroconvulsive Therapy; Humans; Imipramine; Mental Status Schedule; Thyrotropin; Thyr | 1976 |
[Is the thyrotropic hormone an antidepressive agent?].
Topics: Animals; Antidepressive Agents; Depression; Humans; Imipramine; Monoamine Oxidase Inhibitors; Thyrot | 1976 |
A statistical review of controlled trials of imipramine and placebo in the treatment of depressive illnesses.
Topics: Adjustment Disorders; Ambulatory Care; Clinical Trials as Topic; Depression; Drug Evaluation; Hospit | 1975 |
Depression and selective serotonin reuptake inhibitors.
Topics: Adolescent; Adult; Aged; Antidepressive Agents; Depression; Fluoxetine; Humans; Imipramine; Meta-Ana | 1990 |
Biochemical effects of antidepressant treatment--studies of monoamine metabolites in cerebrospinal fluid and platelet [3H]imipramine binding.
Topics: Antidepressive Agents; Blood Platelets; Depression; Homovanillic Acid; Humans; Hydroxyindoleacetic A | 1986 |
Amygdala, depression and drug treatment.
Topics: Amygdala; Animals; Antidepressive Agents; Depression; Disease Models, Animal; Humans; Imipramine; Mo | 1989 |
Self-evaluations of antidepressants.
Topics: Amitriptyline; Antidepressive Agents; Chlordiazepoxide; Clinical Trials as Topic; Depression; Desipr | 1974 |
Depressions following reserpine: a reevaluation.
Topics: Administration, Oral; Depression; Dreams; Drug Therapy, Combination; Electroconvulsive Therapy; Huma | 1971 |
Clinical experience with a new psychotropic drug, trazodone: a review of literature.
Topics: Amitriptyline; Antidepressive Agents; Anxiety; Chlordiazepoxide; Clinical Trials as Topic; Depressio | 1973 |
The biochemistry of the functional psychoses.
Topics: Acetylcholinesterase; Adenosine Triphosphatases; Animals; Behavior, Animal; Blood Proteins; Catatoni | 1967 |
Antidepressant drugs and sleep.
Topics: Adult; Amitriptyline; Animals; Antidepressive Agents; Arousal; Brain; Cats; Depression; Desipramine; | 1969 |
The pharmacology of disordered sleep: a laboratory approach.
Topics: Amitriptyline; Anxiety; Arousal; Barbiturates; Brain; Cerebral Cortex; Depression; Desipramine; Huma | 1970 |
Biochemistry of depression (a review of the literature).
Topics: Adrenal Glands; Amines; Biogenic Amines; Brain Chemistry; Carbohydrate Metabolism; Catecholamines; C | 1971 |
The pharmacodynamics of depression and its relation to therapy.
Topics: Adrenal Glands; Amitriptyline; Animals; Biological Transport, Active; Blood-Brain Barrier; Brain Che | 1974 |
Cutting the REM nerve: an approach to the adaptive role of REM sleep.
Topics: Adaptation, Psychological; Animals; Anxiety; Avoidance Learning; Defense Mechanisms; Depression; Ele | 1974 |
Psychochemical research studies in man.
Topics: Animals; Behavior; Bipolar Disorder; Brain; Brain Chemistry; Depression; Dihydroxyphenylalanine; Hal | 1968 |
Medical-psychological implications of recent sleep research.
Topics: Adaptation, Psychological; Amphetamine; Barbiturates; Central Nervous System Stimulants; Chloral Hyd | 1970 |
Drug therapoy of clinical depressions--current status and implications for research on neuropharmacology of the affective disorders.
Topics: Adjustment Disorders; Affective Symptoms; Amphetamine; Antidepressive Agents; Antipsychotic Agents; | 1972 |
The NIMH collaborative depression studies--a progress report.
Topics: Chlorpromazine; Clinical Trials as Topic; Depression; Diazepam; Drug Combinations; Female; Follow-Up | 1972 |
Lithium salts in the management of the manic-depressive syndrome.
Topics: Acute Disease; Bipolar Disorder; Catecholamines; Chlorpromazine; Depression; Diabetes Insipidus; Glu | 1972 |
The clinical pharmacology of imipramine. Implications for therapeutics.
Topics: Administration, Oral; Barbiturates; Cell Membrane Permeability; Depression; Desipramine; Drug Intera | 1973 |
[Appraisal of pharmacotherapy of affective disorders].
Topics: Adolescent; Depression; Desipramine; Female; Humans; Imipramine; Male; Middle Aged; Monoamine Oxidas | 1973 |
Psychopharmacology. Yesterday, today and tomorrow: a point of view.
Topics: Affective Symptoms; Amitriptyline; Antidepressive Agents; Canada; Carbonates; Depression; Dihydroxyp | 1973 |
Research report: Institute of Psychiatry Clinical Psychopharmacology Research Team.
Topics: Antidepressive Agents; Anxiety; Barbiturates; Conversion Disorder; Depression; Drug Combinations; Dr | 1974 |
MHPG excretion by patients with affective disorders.
Topics: Affective Symptoms; Bipolar Disorder; Brain; Catecholamines; Creatinine; Depression; Desipramine; De | 1974 |
Individualization of treatment with tricyclic compounds.
Topics: Animals; Antidepressive Agents; Chromatography, Gas; Clomipramine; Depression; Drug Interactions; El | 1974 |
[Studies on the biochemistry and pharmacology of thymoleptics].
Topics: Amines; Animals; Antidepressive Agents; Behavior, Animal; Brain Chemistry; Catecholamines; Cats; Dep | 1968 |
[Treatment of endogenous depression with psychopharmaceutics].
Topics: Amitriptyline; Antidepressive Agents; Chlordiazepoxide; Chlorprothixene; Depression; Diazepam; Human | 1967 |
Psychopharmacology: a review.
Topics: Amitriptyline; Antidepressive Agents; Anxiety; Butyrophenones; Chlordiazepoxide; Chlorprothixene; De | 1968 |
[Introductory remarks: on the status of therapy with antidepressive agents].
Topics: Antidepressive Agents; Delayed-Action Preparations; Depression; Dibenzazepines; Electric Stimulation | 1969 |
Clinical experience with lithium carbonate.
Topics: Adult; Aged; Antidepressive Agents; Bipolar Disorder; Carbonates; Central Nervous System; Depression | 1970 |
Clinical and heuristic value of clinical drug research.
Topics: Affective Symptoms; Amitriptyline; Amphetamine; Butyrophenones; Child Behavior Disorders; Chlorproma | 1970 |
[Current problems of the clinical aspects and treatment of depressive states].
Topics: Adjustment Disorders; Age Factors; Ambulatory Care; Amitriptyline; Chlordiazepoxide; Chlorpromazine; | 1969 |
Physiological measures in psychiatry.
Topics: Adaptation, Psychological; Amobarbital; Animals; Anxiety; Arousal; Blood Pressure; Depression; Elect | 1971 |
Indications for tricyclic antidepressant drugs.
Topics: Antidepressive Agents; Chlorpromazine; Depression; Desipramine; Drug Interactions; Humans; Imipramin | 1971 |
Clinical pharmacology of imipramine and related antidepressant compounds.
Topics: Antidepressive Agents; Depression; Humans; Imipramine | 1967 |
272 trials available for imipramine and Depression
| Article | Year |
|---|---|
Fluoxetine and imipramine: are there differences in cost-utility for depression in primary care?
Topics: Adult; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Costs and Cost An | 2009 |
Efficacy and safety of oral magnesium supplementation in the treatment of depression in the elderly with type 2 diabetes: a randomized, equivalent trial.
Topics: Aged; Antidepressive Agents; Depression; Diabetes Mellitus, Type 2; Humans; Imipramine; Magnesium; M | 2008 |
The systolic blood pressure response of depressed patients to infused norepinephrine.
Topics: Adrenergic alpha-Agonists; Adult; Antidepressive Agents, Tricyclic; Blood Pressure; Depression; Fema | 1967 |
Prognostic prediction of therapeutic response in depression using high-field MR imaging.
Topics: Adult; Algorithms; Antidepressive Agents; Brain; Depression; Female; Humans; Image Enhancement; Imag | 2011 |
Antidepressant effects of TNF-α blockade in an animal model of depression.
Topics: Analysis of Variance; Animals; Antidepressive Agents; Body Weight; Depression; Disease Models, Anima | 2013 |
Therapeutic outcome in neuropathic pain: relationship to evidence of nervous system lesion.
Topics: Acetates; Adult; Aged; Amines; Chi-Square Distribution; Cyclohexanecarboxylic Acids; Depression; Dos | 2004 |
Comparison of Crocus sativus L. and imipramine in the treatment of mild to moderate depression: a pilot double-blind randomized trial [ISRCTN45683816].
Topics: Adult; Crocus; Depression; Double-Blind Method; Female; Humans; Imipramine; Male; Phytotherapy; Pilo | 2004 |
Effect of age and gender on citalopram and desmethylcitalopram steady-state plasma concentrations in adults and elderly depressed patients.
Topics: Aged; Aged, 80 and over; Aging; Antidepressive Agents; Citalopram; Depression; Dose-Response Relatio | 2005 |
A pattern of antidepressive effect of tryptophan & imipramine in males & females.
Topics: Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Depression; Double-Blind | 1974 |
Water distribution in affective disorders.
Topics: Adult; Body Fluids; Depression; Electroshock; Extracellular Space; Female; Humans; Imipramine; Male; | 1967 |
The interaction of psychopharmacology and psychoanalysis in the borderline patient.
Topics: Affect; Anger; Antipsychotic Agents; Borderline Personality Disorder; Chlorpromazine; Clinical Trial | 1980 |
Controlled trial of imipramine for chronic low back pain.
Topics: Adult; Back Pain; Depression; Drug Evaluation; Female; Humans; Imipramine; Male; Prospective Studies | 1982 |
Tricyclic antidepressants in obsessive-compulsive disorder. Antiobsessional or antidepressant agents?
Topics: Adolescent; Adult; Aged; Anxiety; Clinical Trials as Topic; Clomipramine; Depression; Female; Humans | 1983 |
Speed of onset of action of the newer antidepressants.
Topics: Amitriptyline; Amoxapine; Antidepressive Agents; Clinical Trials as Topic; Depression; Depressive Di | 1984 |
The efficacy of amoxapine, maprotiline, and trazodone in comparison to imipramine and amitriptyline: a review of the literature.
Topics: Amitriptyline; Amoxapine; Anthracenes; Clinical Trials as Topic; Depression; Dibenzoxazepines; Human | 1984 |
Differential effects of cognitive therapy and pharmacotherapy on depressive symptoms.
Topics: Clinical Trials as Topic; Depression; Emotions; Follow-Up Studies; Humans; Imipramine; Motivation; P | 1981 |
Trimipramine maleate (Surmontil)--another tricyclic antidepressant.
Topics: Antidepressive Agents; Clinical Trials as Topic; Depression; Dibenzazepines; Double-Blind Method; Hu | 1980 |
Imipramine treatment of prepubertal major depressive disorders: plasma levels and clinical response--preliminary report.
Topics: Child; Clinical Trials as Topic; Depression; Double-Blind Method; Humans; Imipramine | 1980 |
A double-blind comparative trial of dothiepin and imipramine for the treatment of depressive inpatients.
Topics: Adult; Clinical Trials as Topic; Depression; Dibenzothiepins; Dothiepin; Double-Blind Method; Female | 1980 |
Trazodone, a triazolopyridine derivative, in primary depressive disorder.
Topics: Adolescent; Adult; Aged; Clinical Trials as Topic; Depression; Double-Blind Method; Female; Humans; | 1980 |
Pharmacokinetics and clinical response to tricyclic antidepressants.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Clinical Trials as Topic; Depression; Humans; Imipr | 1980 |
Trazodone efficacy and safety in endogenous depression: a double blind comparison with imipramine.
Topics: Adult; Clinical Trials as Topic; Depression; Double-Blind Method; Female; Humans; Imipramine; Male; | 1980 |
[Double blind comparison of the antidepressives viloxazine and imipramine (author's transl)].
Topics: Adolescent; Adult; Aged; Anxiety Disorders; Depression; Double-Blind Method; Female; Humans; Imipram | 1982 |
Treatment of endogenous anxiety with phobic, hysterical, and hypochondriacal symptoms.
Topics: Adult; Anxiety; Depression; Double-Blind Method; Female; Humans; Hypochondriasis; Hysteria; Imiprami | 1980 |
A comparative study of viloxazine and imipramine in the treatment of depressive states.
Topics: Adult; Depression; Female; Humans; Imipramine; Male; Morpholines; Psychiatric Status Rating Scales; | 1980 |
A comparison of trimipramine and imipramine: a controlled study.
Topics: Adult; Depression; Dibenzazepines; Female; Humans; Imipramine; Male; Psychiatric Status Rating Scale | 1980 |
Treatment of geriatric depression with trazodone, imipramine, and placebo: a double-blind study.
Topics: Aged; Depression; Double-Blind Method; Female; Humans; Imipramine; Male; Middle Aged; Piperazines; P | 1980 |
Treatment of chronic depression with sertraline or imipramine: preliminary blinded response rates and high rates of undertreatment in the community.
Topics: 1-Naphthylamine; Adult; Affective Disorders, Psychotic; Aged; Chronic Disease; Depression; Female; F | 1995 |
Cost utility analysis of maintenance treatment for recurrent depression.
Topics: Adult; Aged; Combined Modality Therapy; Cost-Benefit Analysis; Costs and Cost Analysis; Depression; | 1995 |
Effectiveness and tolerance of the hypericum extract LI 160 in comparison with imipramine: randomized double-blind study with 135 outpatients.
Topics: Adult; Aged; Antidepressive Agents; Depression; Double-Blind Method; Female; Humans; Hypericum; Imip | 1994 |
Paroxetine in the treatment of Chinese patients with depressive episode: a double-blind randomized comparison with imipramine.
Topics: Adult; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Depression; Doubl | 1996 |
Applications of a mixture survival model with covariates to the analysis of a depression prevention trial.
Topics: Antidepressive Agents, Tricyclic; Depression; Female; Humans; Imipramine; Likelihood Functions; Male | 1996 |
The efficacy of antidepressants in post-stroke depression.
Topics: Adult; Aged; Aged, 80 and over; Amitriptyline; Amoxapine; Antidepressive Agents, Tricyclic; Cerebrov | 1997 |
Amisulpride versus imipramine and placebo in dysthymia and major depression. Amisulpride Study Group.
Topics: Adult; Aged; Amisulpride; Antidepressive Agents; Antidepressive Agents, Tricyclic; Depression; Depre | 1997 |
Efficacy of venlafaxine in depressive illness in general practice.
Topics: Adult; Analysis of Variance; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyc | 1997 |
Bipolar depression: an underestimated treatment challenge.
Topics: Adult; Antidepressive Agents; Antimanic Agents; Bipolar Disorder; Chi-Square Distribution; Cross-Sec | 1997 |
Atypical features and treatment response in the National Institute of Mental Health Treatment of Depression Collaborative Research Program.
Topics: Algorithms; Antidepressive Agents, Tricyclic; Cognitive Behavioral Therapy; Depression; Humans; Imip | 1998 |
Imipramine and diet counseling with psychological support in the treatment of obese binge eaters: a randomized, placebo-controlled double-blind study.
Topics: Adrenergic Uptake Inhibitors; Adult; Counseling; Depression; Double-Blind Method; Energy Intake; Fee | 1999 |
Depressed in-patients respond differently to imipramine and mirtazapine.
Topics: Adrenergic alpha-Antagonists; Adult; Analysis of Variance; Antidepressive Agents, Tricyclic; Anxiety | 1999 |
Antidepressant efficacy of sertraline and imipramine for the treatment of major depression in elderly outpatients.
Topics: Aged; Antidepressive Agents, Tricyclic; Depression; Double-Blind Method; Follow-Up Studies; Humans; | 2000 |
Comparison of St John's wort and imipramine for treating depression: randomised controlled trial.
Topics: Adult; Antidepressive Agents, Tricyclic; Depression; Double-Blind Method; Female; Humans; Hypericum; | 2000 |
Marital adjustment and outcome following treatments for depression.
Topics: Adult; Analysis of Variance; Antidepressive Agents, Tricyclic; Depression; Female; Follow-Up Studies | 2001 |
Noradrenergic function and clinical outcome in antidepressant pharmacotherapy.
Topics: Adrenergic Uptake Inhibitors; Antidepressive Agents; Depression; Fluvoxamine; Humans; Imipramine; Me | 2001 |
Can improvement in well-being and functioning be distinguished from depression improvement in antidepressant clinical trials?
Topics: Activities of Daily Living; Adult; Analysis of Variance; Antidepressive Agents, Second-Generation; A | 2002 |
Oxypertine in combination with imipramine: a controlled trial.
Topics: Adult; Clinical Trials as Topic; Depression; Double-Blind Method; Drug Synergism; Female; Humans; Im | 1978 |
[Study of a beta-adrenergic stimulant and its antidepressant activity in man].
Topics: Adrenergic Agonists; Albuterol; Animals; Antidepressive Agents, Tricyclic; Clinical Trials as Topic; | 1977 |
Letter: Tryptophan/imipramine in depression.
Topics: Adult; Clinical Trials as Topic; Depression; Drug Evaluation; Female; Follow-Up Studies; Humans; Imi | 1975 |
Decreased uptake of 5-hydroxytryptamine in blood platelets from patients with endogenous depression.
Topics: Adult; Amoxapine; Blood Platelets; Depression; Female; Humans; Imipramine; Kinetics; Male; Middle Ag | 1979 |
Studies on pituitary hormones and releasing hormones in depression and sexual impotence.
Topics: 5-Hydroxytryptophan; Benserazide; Bipolar Disorder; Clinical Trials as Topic; Depression; Erectile D | 1975 |
Use of synthesis inhibitors in defining a role for biogenic amines during imipramine treatment in depressed patients.
Topics: 3-Methoxy-4-hydroxyphenylethanol; Adult; Antimetabolites; Biogenic Amines; Clinical Trials as Topic; | 1975 |
Tofranil in the treatment of low back pain.
Topics: Adolescent; Adult; Back Pain; Chronic Disease; Clinical Trials as Topic; Depression; Drug Evaluation | 1976 |
Tryptophan dosage critical for its antidepressant effect.
Topics: Clinical Trials as Topic; Depression; Double-Blind Method; Drug Synergism; Humans; Imipramine; Niaci | 1978 |
Tryptophan-nicotinamide, imipramine and their combination in depression. A controlled study.
Topics: Adult; Bipolar Disorder; Clinical Trials as Topic; Depression; Double-Blind Method; Drug Evaluation; | 1979 |
REM sleep reduction effects on depression syndromes.
Topics: Adjustment Disorders; Adult; Clinical Trials as Topic; Depression; Electroconvulsive Therapy; Electr | 1975 |
Cardiac antiarrhythmic effect of imipramine hydrochloride.
Topics: Aged; Anti-Arrhythmia Agents; Bundle-Branch Block; Clinical Trials as Topic; Depression; Dose-Respon | 1977 |
Comparative clinical evaluation of lofepramine and imipramine. Psychiatric aspects.
Topics: Adult; Clinical Trials as Topic; Depression; Drug Evaluation; Female; Humans; Imipramine; Male; Midd | 1977 |
Comparative clinical evaluation of lofepramine and imipramine. Pharmacological aspects.
Topics: Adult; Chromatography, Gas; Clinical Trials as Topic; Depression; Desipramine; Drug Evaluation; Fema | 1977 |
Which tricyclic for depressed outpatients, imipramine pamoate or amitriptyline?
Topics: Adjustment Disorders; Adult; Ambulatory Care; Amitriptyline; Anxiety; Clinical Trials as Topic; Depr | 1977 |
Contrasts in antidepressant medications.
Topics: Adult; Clinical Trials as Topic; Depression; Double-Blind Method; Drug Evaluation; Female; Humans; I | 1977 |
Controlled randomized group comparison of nomifensine and imipramine in depressive illness.
Topics: Adult; Clinical Trials as Topic; Depression; Double-Blind Method; Drug Evaluation; Female; Humans; I | 1977 |
A review of controlled studies with nomifensine, performed outside the UK.
Topics: Adult; Aged; Amitriptyline; Clinical Trials as Topic; Depression; Double-Blind Method; Doxepin; Drug | 1977 |
The treatment of depression with L-5-hydroxytryptophan versus imipramine. Results of two open and one double-blind study.
Topics: 5-Hydroxytryptophan; Adult; Clinical Trials as Topic; Depression; Double-Blind Method; Drug Synergis | 1977 |
[Mianserin and imipramin in depressive conditions (author's transl)].
Topics: Adult; Clinical Trials as Topic; Depression; Dibenzazepines; Drug Evaluation; Female; Humans; Imipra | 1977 |
Blood levels of tricyclic antidepressant drugs: assay procedures, reproducibility and relationship to therapeutic outcome and side effects.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Clinical Trials as Topic; Depression; Double-Blind | 1977 |
Electroencephalogram study of mianserin in depressed patients.
Topics: Adolescent; Adult; Aged; Brain; Clinical Trials as Topic; Depression; Dibenzazepines; Dose-Response | 1978 |
A double-blind multicentre trial comparing mianserin with imipramine.
Topics: Adjustment Disorders; Adolescent; Adult; Affective Disorders, Psychotic; Aged; Clinical Trials as To | 1978 |
Nomifensin in the treatment of depression: a report on the Canadian part of a transcultural study.
Topics: Adjustment Disorders; Adult; Canada; Clinical Trials as Topic; Cross-Cultural Comparison; Depression | 1978 |
Doxepin and imipramine in the treatment of depression: a double-blind crossover clinical study with EKG recordings.
Topics: Adjustment Disorders; Adult; Bipolar Disorder; Clinical Trials as Topic; Depression; Double-Blind Me | 1978 |
Nomifensin in the treatment of depression: a standard-controlled clinical study.
Topics: Adult; Clinical Trials as Topic; Depression; Double-Blind Method; Female; Humans; Imipramine; Isoqui | 1978 |
Initial response to drugs in depressive illness and psychiatric and community adjustment a year later.
Topics: Adjustment Disorders; Adult; Affective Disorders, Psychotic; Chlorpromazine; Clinical Trials as Topi | 1978 |
Plasma and erythrocyte levels of tricyclic antidepressants in depressed patients.
Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Biopharmaceutics; Clinical Trials as Topic; | 1978 |
Prophylactic effect of lithium and imipramine in unipolar and bipolar II patients: a preliminary report.
Topics: Bipolar Disorder; Clinical Trials as Topic; Depression; Drug Evaluation; Drug Therapy, Combination; | 1978 |
[Differential indications for desipramine--results of a controlled multiclinical study].
Topics: Clinical Trials as Topic; Depression; Desipramine; Double-Blind Method; Humans; Imipramine | 1978 |
Imipramine-reversible cognitive deficit in outpatient depressives [proceedings].
Topics: Adult; Clinical Trials as Topic; Cognition Disorders; Depression; Double-Blind Method; Humans; Imipr | 1978 |
Imipramine response in deluded depressive patients.
Topics: Adult; Bipolar Disorder; Clinical Trials as Topic; Delusions; Depression; Drug Evaluation; Female; H | 1978 |
[A comparison of the antidepressive effects of danitracene and imipramine (author's transl)].
Topics: Adolescent; Adult; Aged; Anthracenes; Antidepressive Agents, Tricyclic; Chemical Phenomena; Chemistr | 1978 |
Prediction of imipramine antidepressant response by a one-day dextro-amphetamine trial.
Topics: Adolescent; Adult; Circadian Rhythm; Clinical Trials as Topic; Depression; Dextroamphetamine; Double | 1978 |
Differential effects of a single dose of imipramine and lopramine in healthy subjects varying in their level of depression.
Topics: Adult; Clinical Trials as Topic; Depression; Dibenzazepines; Drug Evaluation; Humans; Imipramine; Lo | 1977 |
Imipramine and desipramine in plasma and spinal fluid: relationship to clinical response and serotonin metabolism.
Topics: Adult; Bipolar Disorder; Brain; Clinical Trials as Topic; Depression; Desipramine; Double-Blind Meth | 1978 |
Comparisons of maprotiline with imipramine in severe depression: a multicenter controlled trial.
Topics: Adolescent; Adult; Aged; Anthracenes; Clinical Trials as Topic; Depression; Double-Blind Method; Fem | 1979 |
Comparison of efficacy of amoxapine and imipramine in a multi-clinic double-blind study using the WHO schedule for a standard assessment of patients with depressive disorders.
Topics: Amoxapine; Clinical Trials as Topic; Depression; Dibenzoxazepines; Double-Blind Method; Drug Evaluat | 1979 |
A double-blind evaluation of nomifensine and imipramine in depressed outpatients.
Topics: Adolescent; Adult; Aged; Clinical Trials as Topic; Depression; Double-Blind Method; Humans; Imiprami | 1979 |
Trazodone, a new antidepressant: efficacy and safety in endogenous depression.
Topics: Adult; Aged; Anxiety; Clinical Trials as Topic; Depression; Double-Blind Method; Female; Humans; Imi | 1979 |
Controlled studies of the acute antidepressant effects of lithium.
Topics: Adult; Aged; Bipolar Disorder; Clinical Trials as Topic; Depression; Double-Blind Method; Drug Combi | 1979 |
[A comparative study of viloxazine and imipramine (author's transl)].
Topics: Adult; Aged; Clinical Trials as Topic; Depression; Electrocardiography; Electroencephalography; Fema | 1979 |
[Differential indication of trimipramine - results of a controlled multiclinical study].
Topics: Clinical Trials as Topic; Depression; Dibenzazepines; Double-Blind Method; Drug Evaluation; Humans; | 1979 |
Comparative efficacy of nomifensine and imipramine.
Topics: Clinical Trials as Topic; Depression; Double-Blind Method; Humans; Imipramine; Isoquinolines; Middle | 1979 |
Symptom reduction in depression after treatment with L-tryptophan or imipramine. Item analysis of Hamilton rating scale for depression.
Topics: Adolescent; Adult; Aged; Clinical Trials as Topic; Depression; Double-Blind Method; Female; Humans; | 1979 |
DL-phenylalanine versus imipramine: a double-blind controlled study.
Topics: Adult; Aged; Clinical Trials as Topic; Depression; Double-Blind Method; Drug Evaluation; Female; Hum | 1979 |
Comparison of Vivalan (viloxazine hydrochloride) with imipramine in the treatment of depression. A double-blind study.
Topics: Adjustment Disorders; Adult; Aged; Clinical Trials as Topic; Depression; Double-Blind Method; Drug E | 1979 |
[Therapeutical effect of mianserin and imipramine in endogenous depressions (controlled comparison) (author's transl)].
Topics: Adolescent; Adult; Aged; Clinical Trials as Topic; Depression; Dibenzazepines; Double-Blind Method; | 1979 |
Lack of effect of tricyclic antidepressants on serum prolactin levels.
Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Depression; Female; Humans; Imipramine; Male | 1977 |
Treatment of endogenous depressions with thyrotropin-releasing hormone (TRH) under oral administration.
Topics: Administration, Oral; Clinical Trials as Topic; Depression; Drug Evaluation; Female; Humans; Imipram | 1977 |
Imipramine: clinical effects and pharmacokinetic variability.
Topics: Adult; Age Factors; Aged; Clinical Trials as Topic; Depression; Female; Humans; Imipramine; Kinetics | 1977 |
Prediction of antidepressant responses to imipramine.
Topics: Depression; Double-Blind Method; Female; Humans; Imipramine; Male; MMPI; Prognosis; Sex Factors | 1979 |
Amoxapine in depressive illness.
Topics: Amoxapine; Depression; Dibenzoxazepines; Double-Blind Method; Female; Humans; Imipramine; Male; Midd | 1979 |
Letter: Tryptophan and depression.
Topics: Clinical Trials as Topic; Depression; Humans; Imipramine; Tryptophan | 1976 |
[Pharmacologic action of rubidium chloride. Antidepressive effect: comparison with imipramine].
Topics: Adolescent; Adult; Aged; Clinical Trials as Topic; Depression; Drug Evaluation; Female; Humans; Imip | 1975 |
Treatment of depression in the aged with gerovital H3: clinical efficacy and neurophysiological effects.
Topics: Aged; Clinical Trials as Topic; Depression; Humans; Imipramine; Middle Aged; Placebos; Procaine; Psy | 1976 |
Influence of imipramine on the circulatory system in the course of endogenous depressive syndromes. I. Evaluation of the basic parameters of the circulatory system.
Topics: Adult; Blood Pressure; Clinical Trials as Topic; Depression; Female; Hemodynamics; Humans; Imipramin | 1975 |
Plasma levels and antidepressive effect of imipramine.
Topics: Adult; Antidepressive Agents; Clinical Trials as Topic; Depression; Desipramine; Female; Humans; Imi | 1976 |
Comparison of a new antidepressive, lofepramine, with imipramine in a double-blind multicentre trial.
Topics: Adolescent; Adult; Aged; Antidepressive Agents, Tricyclic; Clinical Trials as Topic; Depression; Dib | 1975 |
Two dosages of imipramine in hospitalized endogenous and neurotic depressives.
Topics: Adjustment Disorders; Adult; Bipolar Disorder; Clinical Trials as Topic; Delusions; Depression; Dose | 1976 |
[Doubleblind study with the novel antidepressant viloxazine versus imipramine in 50 in-patients (author's transl)].
Topics: Antidepressive Agents; Clinical Trials as Topic; Depression; Female; Humans; Imipramine; Middle Aged | 1976 |
Controlled trials of imipramine.
Topics: Clinical Trials as Topic; Depression; Drug Evaluation; Humans; Imipramine | 1976 |
[Experiences with Petylyl (desipramine) in antidepressive therapy. Double blind test with Pryleugan (imipramine)].
Topics: Clinical Trials as Topic; Depression; Desipramine; Drug Evaluation; Humans; Imipramine | 1976 |
Mianserin in the treatment of depression in general practice.
Topics: Adolescent; Adult; Aged; Clinical Trials as Topic; Depression; Dibenzazepines; Female; Humans; Imipr | 1976 |
Prediction of tricyclic antidepressant response: a critical review.
Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Clinical Trials as Topic; Depression; Drug E | 1976 |
Amoxapine, imipramine and placebo in depressive illness.
Topics: Adult; Amoxapine; Clinical Trials as Topic; Depression; Dibenzoxazepines; Female; Humans; Imipramine | 1975 |
A double-blind comparative clinical trial with maprotiline (Ludiomil) and imipramine in newly-admitted depressed patients.
Topics: Adult; Aged; Ambulatory Care; Analysis of Variance; Anthracenes; Antidepressive Agents; Clinical Tri | 1976 |
Maprotiline (Ludiomil, Ciba 34,276-BA) and imipramine in depressed outpatients: a double-blind clinical study.
Topics: Adult; Ambulatory Care; Analysis of Variance; Anthracenes; Antidepressive Agents; Anxiety; Clinical | 1976 |
[The effect of thyrotrophin releasing hormone versus placebo in combination with basic imipramine therapy of depressive patients].
Topics: Adult; Clinical Trials as Topic; Depression; Drug Therapy, Combination; Female; Humans; Imipramine; | 1976 |
Drug-related test patterns of depressed patients.
Topics: Adolescent; Adult; Aged; Attention; Chlorpromazine; Depression; Female; Humans; Imipramine; Male; Me | 1976 |
Open trial and double-blind clinical trial of the antidepressant Ro 8-1998 in comparison with imipramine.
Topics: Adult; Aged; Antidepressive Agents, Tricyclic; Depression; Dibenzocycloheptenes; Drug Evaluation; Fe | 1977 |
A sequential trial of viloxazine (Vivalan) and imipramine in moderately depressed patients.
Topics: Adult; Depression; Female; Humans; Imipramine; Male; Morpholines; Viloxazine | 1977 |
The endogenous--neurotic distinction as a predictor of response to antidepressant drugs.
Topics: Adjustment Disorders; Adolescent; Adult; Aged; Antidepressive Agents; Anxiety; Chlorpromazine; Depre | 1976 |
Antidepressant response to tricyclics and urinary MHPG in unipolar patients. Clinical response to imipramine or amitriptyline.
Topics: Adult; Aged; Amitriptyline; Clinical Trials as Topic; Depression; Female; Glycols; Humans; Imipramin | 1975 |
Antidepressants in black and white inpatients. Differential response to a controlled trial of chlorpromazine and imipramine.
Topics: Adult; Age Factors; Anxiety; Black or African American; Chlorpromazine; Clinical Trials as Topic; De | 1975 |
Double-blind comparison of lithium carbonate and imipramine in treatment of depression.
Topics: Adjustment Disorders; Adult; Carbonates; Clinical Trials as Topic; Depression; Dose-Response Relatio | 1975 |
Viloxazine- a new antidepressive drug.
Topics: Antidepressive Agents; Clinical Trials as Topic; Depression; Dose-Response Relationship, Drug; Drug | 1975 |
Depression, Delusions, and Drug Response.
Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Clinical Trials as Topic; Delusions; Depress | 1975 |
[Clinical trial of lofepramine versus imipramine].
Topics: Acetophenones; Adult; Clinical Trials as Topic; Constipation; Depression; Dibenzazepines; Drug Evalu | 1975 |
A controlled study of a tetracyclic antidepressant--maprotiline (Ludiomil).
Topics: Adjustment Disorders; Adult; Anthracenes; Bipolar Disorder; Body Weight; Clinical Trials as Topic; D | 1975 |
The Hamilton rating scale. An assessment bases on a dothiepin ("prothiaden") versus imipramine ("Tofranil") clinical trial.
Topics: Clinical Trials as Topic; Depression; Dibenzothiepins; Dothiepin; Humans; Imipramine; Psychiatric St | 1975 |
[Controlled double-blind study (SAMe-imipramine) in depressive syndromes].
Topics: Administration, Oral; Adult; Aged; Clinical Trials as Topic; Depression; Drug Evaluation; Female; Hu | 1975 |
Imipramine pamoate in depression.
Topics: Adult; Aged; Bipolar Disorder; Clinical Trials as Topic; Depression; Drug Evaluation; Female; Humans | 1975 |
A double-blind trial of maprotiline (Ludiomil) and amitriptyline in depressed outpatients.
Topics: Adult; Aged; Amitriptyline; Analysis of Variance; Anthracenes; Clinical Trials as Topic; Depression; | 1975 |
A statistical review of controlled trials of imipramine and placebo in the treatment of depressive illnesses.
Topics: Adjustment Disorders; Ambulatory Care; Clinical Trials as Topic; Depression; Drug Evaluation; Hospit | 1975 |
Effect of ECT and imipramine treatment on the concentration of 5-hydroxyindoleacetic acid (5HIAA) and homovanillic acid (HVA) in the cerebrospinal fluid of depressed patients.
Topics: Adult; Clinical Trials as Topic; Depression; Electroconvulsive Therapy; Female; Homovanillic Acid; H | 1975 |
Pharmacodynamics of imipramine in depressed patients.
Topics: Clinical Trials as Topic; Depression; Desipramine; Half-Life; Humans; Imipramine; Phenylbutazone | 1975 |
Proceedings: Systematic clinical studies with clomipramine in depressed psychiatric patients--III. Standard-controlled clinical trial.
Topics: Adult; Clinical Trials as Topic; Clomipramine; Depression; Dibenzazepines; Female; Humans; Imipramin | 1976 |
Treatment of depression in alcoholics.
Topics: Adolescent; Adult; Alcoholism; Chlordiazepoxide; Counseling; Depression; Drug Evaluation; Drug Thera | 1975 |
Proceedings: The evaluation of the effect of trimeproprimine and imipramine in a double blind trial.
Topics: Adolescent; Adult; Aged; Antidepressive Agents; Depression; Drug Evaluation; Humans; Imipramine; Mid | 1975 |
A clinical evaluation of depressives found in a rural survey in India.
Topics: Depression; Humans; Imipramine; India; Placebos; Psychological Tests; Recurrence; Rural Population; | 1976 |
Can mildly depressed outpatients with atypical depression benefit from antidepressants?
Topics: Adolescent; Adult; Aged; Ambulatory Care; Antidepressive Agents; Depression; Depressive Disorder; Fe | 1992 |
Pharmacotherapy for posttraumatic stress disorder using phenelzine or imipramine.
Topics: Adult; Ambulatory Care; Anxiety; Depression; Double-Blind Method; Humans; Imipramine; Male; Personal | 1991 |
High-dose fluoxetine: efficacy and activating-sedating effects in agitated and retarded depression.
Topics: Adolescent; Adult; Aged; Depression; Drug Administration Schedule; Female; Fluoxetine; Humans; Hypno | 1991 |
The selective serotonin reuptake inhibitor paroxetine is effective in the treatment of diabetic neuropathy symptoms.
Topics: Depression; Desipramine; Diabetic Neuropathies; Humans; Imipramine; Nervous System; Osmolar Concentr | 1990 |
Cardiovascular and symptomatic reduction effects of alprazolam and imipramine in patients with panic disorder: results of a double-blind, placebo-controlled trial.
Topics: Adult; Agoraphobia; Alprazolam; Analysis of Variance; Anxiety; Anxiety Disorders; Depression; Disabi | 1990 |
A comparison study of antidepressants and structured intensive group psychotherapy in the treatment of bulimia nervosa.
Topics: Adolescent; Adult; Anorexia Nervosa; Anxiety; Behavior Therapy; Body Weight; Bulimia; Cognitive Beha | 1990 |
A placebo-controlled inpatient comparison of fluvoxamine maleate and imipramine in major depression.
Topics: Adolescent; Adult; Aged; Antidepressive Agents; Clinical Trials as Topic; Depression; Double-Blind M | 1989 |
Initial depression and response to imipramine in agoraphobia.
Topics: Agoraphobia; Clinical Trials as Topic; Depression; Depressive Disorder; Dose-Response Relationship, | 1987 |
Steady-state concentrations of imipramine and its metabolites in relation to the sparteine/debrisoquine polymorphism.
Topics: Adult; Aged; Aged, 80 and over; Clinical Trials as Topic; Debrisoquin; Depression; Desipramine; Fema | 1986 |
Preliminary study of imipramine in profoundly retarded residents.
Topics: Acting Out; Adolescent; Adult; Child; Clinical Trials as Topic; Depression; Double-Blind Method; Hum | 1986 |
Imipramine and placebo in the treatment of obsessive-compulsives: their effect on depression and on obsessional symptoms.
Topics: Adult; Depression; Female; Humans; Imipramine; Male; Obsessive-Compulsive Disorder; Time Factors | 1987 |
Targeted treatment of depression-like symptoms in schizophrenia.
Topics: Benztropine; Depression; Drug Therapy, Combination; Fluphenazine; Humans; Imipramine; Schizophrenia | 1987 |
A single-subject study of imipramine in a mentally retarded woman with depressive symptoms.
Topics: Adult; Depression; Double-Blind Method; Eating; Female; Humans; Imipramine; Intellectual Disability; | 1986 |
Treatment of depression in cancer patients.
Topics: Amitriptyline; Breast Neoplasms; Clinical Trials as Topic; Combined Modality Therapy; Depression; Fe | 1985 |
Diclofensine and imipramine. A double-blind comparative trial in depressive out-patients.
Topics: Adult; Antidepressive Agents; Clinical Trials as Topic; Depression; Double-Blind Method; Female; Hum | 1985 |
Cardiotoxicity of amitriptyline.
Topics: Acute Disease; Adult; Amitriptyline; Arrhythmias, Cardiac; Clinical Trials as Topic; Death, Sudden; | 1972 |
Continuation therapy with tricyclic antidepressants in depressive illness.
Topics: Amitriptyline; Clinical Trials as Topic; Depression; Humans; Imipramine; Placebos; Recurrence | 1972 |
Letter: Tryptophan in depression.
Topics: Clinical Trials as Topic; Depression; Drug Synergism; Humans; Imipramine; Monoamine Oxidase Inhibito | 1974 |
Clomipramine HCL--a double-blind study of a new antidepressant drug.
Topics: Adult; Antidepressive Agents; Anxiety; Clinical Trials as Topic; Depression; Dibenzazepines; Evaluat | 1973 |
Self-evaluations of antidepressants.
Topics: Amitriptyline; Antidepressive Agents; Chlordiazepoxide; Clinical Trials as Topic; Depression; Desipr | 1974 |
Influence of doctors' and patients' attitudes in the treatment of neurotic illness.
Topics: Amitriptyline; Amobarbital; Anxiety Disorders; Attitude; Chlordiazepoxide; Clinical Trials as Topic; | 1967 |
A critical look at antidepressant drug trials.
Topics: Antidepressive Agents; Attitude; Clinical Trials as Topic; Depression; Electroconvulsive Therapy; Hu | 1967 |
Enhancement of imipramine antidepressant activity by thyroid hormone.
Topics: Achilles Tendon; Adult; Clinical Trials as Topic; Depression; Drug Synergism; Female; Humans; Imipra | 1969 |
Comparable therapeutic efficacy of tryptophan and imipramine: average therapeutic ratings versus "true" equivalence. An important difference.
Topics: Clinical Trials as Topic; Depression; Evaluation Studies as Topic; Humans; Imipramine; Psychiatric S | 1973 |
A controlled study of single-dose administration of imipramine pamoate in endogenous depression.
Topics: Adjustment Disorders; Administration, Oral; Adolescent; Adult; Aged; Analysis of Variance; Blood Pre | 1973 |
Clinical experience with a new psychotropic drug, trazodone: a review of literature.
Topics: Amitriptyline; Antidepressive Agents; Anxiety; Chlordiazepoxide; Clinical Trials as Topic; Depressio | 1973 |
Amoxapine and imipramine: a double-blind study in depressed patients.
Topics: Adult; Aged; Antidepressive Agents; Clinical Trials as Topic; Depression; Dibenzoxazepines; Female; | 1973 |
Plasma cortisol response to dexamethasone suppression in depressed and control patients.
Topics: Adjustment Disorders; Adult; Amines; Chlorpromazine; Circadian Rhythm; Depression; Depression, Chemi | 1971 |
Sleep patterns in depression. Longitudinal study of six patients and brief review of literature.
Topics: Adult; Aged; Arousal; Depression; Electroencephalography; Electromyography; Electrooculography; Fema | 1971 |
A guide for drug use in depressive disorders.
Topics: Adolescent; Adult; Aged; Anxiety; Chlorpromazine; Clinical Trials as Topic; Depression; Diazepam; Dr | 1974 |
Effects of imipramine on individuals varying in level of depression.
Topics: Adult; Anxiety; Depression; Humans; Imipramine; Male; MMPI; Placebos | 1968 |
Double-blind, noncrossover study of imipramine and A-10749.
Topics: Administration, Oral; Adult; Aged; Antidepressive Agents; Clinical Trials as Topic; Depression; Eval | 1972 |
The comparative antidepressant value of L-tryptophan and imipramine with and without attempted potentiation by liothyronine.
Topics: Clinical Trials as Topic; Depression; Drug Combinations; Drug Synergism; Evaluation Studies as Topic | 1972 |
Thyroid function and the response to liothyronine in depression.
Topics: Ankle; Cholesterol; Clinical Trials as Topic; Depression; Evaluation Studies as Topic; Female; Human | 1972 |
Catecholamine metabolism, depressive illness, and drug response.
Topics: Adult; Aged; Brain; Brain Chemistry; Catechols; Clinical Trials as Topic; Depression; Desipramine; E | 1972 |
Hormonal potentiation of imipramine and ECT in primary depression.
Topics: Adolescent; Adult; Affective Symptoms; Aged; Clinical Trials as Topic; Depression; Dexamethasone; Dr | 1972 |
Thioridazine as an antidepressant.
Topics: Adolescent; Adult; Aged; Clinical Trials as Topic; Depression; Female; Humans; Imipramine; Male; Mid | 1972 |
The NIMH collaborative depression studies--a progress report.
Topics: Chlorpromazine; Clinical Trials as Topic; Depression; Diazepam; Drug Combinations; Female; Follow-Up | 1972 |
[Status of clinical experiments with the thymoleptic-anxiolytic, dimethacrine].
Topics: Acridines; Amitriptyline; Animals; Antidepressive Agents; Clinical Trials as Topic; Depression; Dibe | 1972 |
A model for drug use with depressed patients.
Topics: Adolescent; Adult; Aged; Analysis of Variance; Attitude to Health; Chlorpromazine; Clinical Trials a | 1973 |
Metabolism, anticholinergic effects, and therapeutic outcome of desmethylimipramine in depressive illness.
Topics: Adult; Aged; Body Weight; Clinical Trials as Topic; Depression; Desipramine; Dose-Response Relations | 1972 |
An evaluation of continuation therapy with tricyclic antidepressants in depressive illness.
Topics: Adult; Aged; Amitriptyline; Clinical Trials as Topic; Depression; Evaluation Studies as Topic; Femal | 1973 |
Comparison of chlorimipramine and imipramine in ambulatory treatment of depression.
Topics: Adult; Affect; Ambulatory Care; Blood Pressure; Clinical Trials as Topic; Depression; Dibenzazepines | 1972 |
A comparative double-blind evaluation of iprindole and imipramine in the treatment of depressive states.
Topics: Adult; Antidepressive Agents; Clinical Trials as Topic; Depression; Female; Humans; Imipramine; Indo | 1973 |
Comparative trial of imipramine N-oxide and imipramine in the treatment of out-patients with depressive syndromes.
Topics: Adult; Clinical Trials as Topic; Depression; Evaluation Studies as Topic; Female; Humans; Imipramine | 1973 |
Lithium carbonate and imipramine in prevention of affective episodes. A comparison in recurrent affective illness.
Topics: Adult; Affective Symptoms; Age Factors; Clinical Trials as Topic; Depression; Female; Hospitalizatio | 1973 |
Iprindole and imipramine in non-psychotic depressed out-patients.
Topics: Adult; Antidepressive Agents; Anxiety; Clinical Trials as Topic; Depression; Family Practice; Female | 1973 |
Methyltestosterone with imipramine in men: conversion of depression to paranoid reaction.
Topics: Adult; Aggression; Clinical Trials as Topic; Depression; Dose-Response Relationship, Drug; Drug Ther | 1974 |
Drugs and group psychotherapy in neurotic depression.
Topics: Adult; Chronic Disease; Clinical Trials as Topic; Depression; Diazepam; Drug Evaluation; Female; Hum | 1974 |
Lithium prophylaxis in recurrent affective illness.
Topics: Acute Disease; Adult; Bipolar Disorder; Clinical Trials as Topic; Depression; Drug Evaluation; Femal | 1974 |
Can self-rating replace doctors's rating in evaluating anti-depressive treatment?
Topics: Antidepressive Agents; Clinical Trials as Topic; Depression; Dibenzazepines; Humans; Imipramine; Psy | 1974 |
Butriptyline hydrochloride and imipramine hydrochloride in the treatment of non-psychotic depression. A double-blind trial.
Topics: Antidepressive Agents; Anxiety; Clinical Trials as Topic; Depression; Dibenzocycloheptenes; Humans; | 1974 |
Effect of imipramine on the rheumatoid factor titre of psychotic patients with depressive symptomatology.
Topics: Adsorption; Antigens; Chronic Disease; Clinical Trials as Topic; Depression; Erythrocytes; Humans; I | 1974 |
Affective disease health maintenance organization. Patterns of lithium response.
Topics: Adult; Aged; Amitriptyline; Antidepressive Agents; Bipolar Disorder; Chlorpromazine; Clinical Trials | 1974 |
The effects of small electrical currents upon depressive symptoms.
Topics: Adult; Awareness; Brain; Chlordiazepoxide; Chlorpromazine; Clinical Trials as Topic; Depression; Ele | 1974 |
True and apparent side effects in a controlled trial of chlorpromazine and imipramine in depression.
Topics: Adult; Agranulocytosis; Chlorpromazine; Clinical Trials as Topic; Depression; Dermatitis; Edema; Eva | 1974 |
[Results of an open and a double-blind study of nomifensin in comparison to imipramin (author's transl)].
Topics: Adjustment Disorders; Adult; Aged; Benzene Derivatives; Bipolar Disorder; Clinical Trials as Topic; | 1974 |
Relationship between serum lithium level and clinical response to depression treated with lithium carbonate.
Topics: Administration, Oral; Clinical Trials as Topic; Community Participation; Depression; Humans; Imipram | 1974 |
Therapy possibilities for therapy-resistant depressions.
Topics: Amitriptyline; Antidepressive Agents; Chronic Disease; Clinical Trials as Topic; Depression; Desipra | 1974 |
Influence-possibilities on therapy-resistant late depressions.
Topics: Aged; Amitriptyline; Antidepressive Agents; Anxiety; Arteriosclerosis; Clinical Trials as Topic; Dep | 1974 |
Clinical aspects of resistance to imipramine therapy.
Topics: Adaptation, Psychological; Bipolar Disorder; Clinical Trials as Topic; Depression; Drug Resistance; | 1974 |
A double-blind controlled study of viloxazine and imipramine in depression.
Topics: Adult; Antidepressive Agents; Blood Pressure; Body Weight; Clinical Trials as Topic; Depression; Eth | 1974 |
A comparative study of N 7001 (Metrisil) and imipramine on a series of depressive patients.
Topics: Anthracenes; Antidepressive Agents; Clinical Trials as Topic; Depression; Drug Evaluation; Humans; I | 1974 |
Effects of amitriptyline and imipramine on amine metabolites in the cerebrospinal fluid of depressed patients.
Topics: Adult; Amitriptyline; Biological Transport; Brain Chemistry; Depression; Dopamine; Female; Homovanil | 1974 |
[Problems of the investigation of antidepressive agents based on the example of a new dibenzodiazepine derivative].
Topics: Clinical Trials as Topic; Depression; Dibenzazepines; Female; Humans; Imipramine; Male | 1966 |
[Clinical experiences with a new thymoleptic].
Topics: Amitriptyline; Antidepressive Agents; Clinical Trials as Topic; Depression; Female; Humans; Imiprami | 1967 |
Clinical trial of a new antidepressant (WY.3263). With assessment of doctor-patient interaction.
Topics: Adult; Aged; Antidepressive Agents; Clinical Trials as Topic; Depression; Female; Humans; Imipramine | 1967 |
Treatment of depression. A comparative trial of imipramine and desipramine.
Topics: Adult; Clinical Trials as Topic; Depression; Desipramine; Female; Humans; Imipramine; Male | 1967 |
Monochlorimipramine: a controlled trial of a new antidepressant.
Topics: Adult; Aged; Antidepressive Agents; Clinical Trials as Topic; Depression; Humans; Imipramine; Middle | 1967 |
Effects of informed consent on research patients a study results.
Topics: Clinical Trials as Topic; Depression; Humans; Imipramine; Placebos; Psychology, Clinical; Volition | 1967 |
Correlation of clinical features of depressed out-patients with response to amitriptyline and protriptyline.
Topics: Adult; Amitriptyline; Antidepressive Agents; Clinical Trials as Topic; Depression; Female; Humans; I | 1968 |
The direct comparison of antidepressants: imipramine and chlorprothixene.
Topics: Adult; Age Factors; Blood Cell Count; Chlorprothixene; Clinical Trials as Topic; Depression; Female; | 1967 |
The action of reserpine in imipramine-resistant depressive patients. Clinical and biochemical study.
Topics: Adult; Bipolar Disorder; Blood Pressure; Body Temperature; Clinical Trials as Topic; Depression; Dru | 1967 |
Prediction of drug effect by diagnostic decision tree.
Topics: Anxiety; Bipolar Disorder; Chlorpromazine; Clinical Trials as Topic; Depression; Factor Analysis, St | 1968 |
A comparative trial of imipramine and chlorpromazine in depressed patients.
Topics: Adult; Analysis of Variance; Anxiety; Chlorpromazine; Clinical Trials as Topic; Depression; Female; | 1968 |
A comparison between imipramine and protriptyline in the treatment of depressed out-patients.
Topics: Adult; Antidepressive Agents; Blood Pressure; Clinical Trials as Topic; Depression; Female; Heart Ra | 1968 |
[On polythymolepsy (combined application of thymoleptics) in endogenous depression].
Topics: Adult; Affective Symptoms; Amitriptyline; Chlordiazepoxide; Chlorpromazine; Clinical Trials as Topic | 1968 |
A controlled comparison between imipramine and protriptyline.
Topics: Aged; Antidepressive Agents; Clinical Trials as Topic; Depression; Female; Humans; Imipramine; Male; | 1968 |
Comparison of imipramine and chlordiazepoxide in the treatment of the depressed and anxious patient.
Topics: Adolescent; Adult; Anxiety; Chlordiazepoxide; Clinical Trials as Topic; Depression; Female; Humans; | 1969 |
[Clinical research with imipramine-N-oxide in mental depression].
Topics: Age Factors; Aged; Clinical Trials as Topic; Depression; Female; Humans; Imipramine; Male; Middle Ag | 1968 |
Psychiatric diagnosis and a typology of clinical drug effects.
Topics: Affective Symptoms; Analysis of Variance; Anger; Bipolar Disorder; Chlorpromazine; Clinical Trials a | 1968 |
The use of lithium in affective disorders. I. Acute endogenous depression.
Topics: Acute Disease; Adult; Aged; Bipolar Disorder; Carbonates; Clinical Trials as Topic; Depression; Fema | 1968 |
The use of lithium in affective disorders. II. Prophylaxis of depression in chronic recurrent affective disorder.
Topics: Adult; Aged; Bipolar Disorder; Carbonates; Clinical Trials as Topic; Depression; Female; Humans; Imi | 1968 |
Depression: prognosis and drug treatment.
Topics: Adolescent; Adult; Age Factors; Aged; Clinical Trials as Topic; Depression; Desipramine; Female; Hum | 1969 |
A double-blind trial with an antidepressant drug, imipramine, in multiple sclerosis.
Topics: Clinical Trials as Topic; Depression; Humans; Imipramine; Multiple Sclerosis; Placebos; Spasm | 1969 |
[Dibenzepin in depression. A controlled clinical trial].
Topics: Adult; Aged; Clinical Trials as Topic; Depression; Dibenzazepines; Female; Humans; Imipramine; Male; | 1967 |
A double-blind comparative trial of dibenzepin and imipramine.
Topics: Adult; Antidepressive Agents; Clinical Trials as Topic; Depression; Dibenzazepines; Humans; Imiprami | 1969 |
A comparative trial of imipramine and phenobarbital in depressed patients seen in general practice.
Topics: Adjustment Disorders; Adolescent; Adult; Aged; Anxiety; Child; Clinical Trials as Topic; Depression; | 1969 |
[Melitracen and imipramine in treatment of depression. A comparative study based on a controlled clinical test].
Topics: Adult; Amitriptyline; Anthracenes; Antidepressive Agents; Clinical Trials as Topic; Depression; Fema | 1968 |
[Noxiptilin in clinic and practice].
Topics: Amitriptyline; Antidepressive Agents; Bipolar Disorder; Central Nervous System; Clinical Trials as T | 1969 |
Cyprolidol and imipramine: a double-blind controlled study in endogenous depression.
Topics: Antidepressive Agents; Arteries; Blood Pressure; Clinical Trials as Topic; Depression; Depressive Di | 1969 |
A comparison of two drug treatments in depressive illness.
Topics: Amitriptyline; Anxiety; Clinical Trials as Topic; Depression; Female; Humans; Imipramine; Male; Midd | 1969 |
Affective disorders and norepinephrine pharmacology.
Topics: Animals; Behavior; Behavior, Animal; Body Temperature; Brain; Brain Chemistry; Chlorpromazine; Clini | 1969 |
Physicians' preferences in a blind trial of imipramine and amitriptyline.
Topics: Adult; Amitriptyline; Analysis of Variance; Attitude of Health Personnel; Clinical Trials as Topic; | 1969 |
Verbal behaviour changes with depression treatment.
Topics: Adolescent; Adult; Amitriptyline; Analysis of Variance; Antidepressive Agents; Clinical Trials as To | 1969 |
The response to treatment of individual patients in a drug trial.
Topics: Antidepressive Agents; Clinical Trials as Topic; Depression; Female; Humans; Imipramine; Indoles; Me | 1969 |
A controlled study of nortriptyline and imipramine.
Topics: Anxiety; Body Weight; Clinical Trials as Topic; Depression; Female; Humans; Imipramine; Nortriptylin | 1970 |
Thyroid-hormone enhancement of imipramine in nonretarded depressions.
Topics: Blood Proteins; Clinical Trials as Topic; Depression; Drug Synergism; Female; Hospitalization; Human | 1970 |
Depressive illness in a general practice. A demographic study and a controlled trial of imipramine.
Topics: Adolescent; Adult; Aged; Clinical Trials as Topic; Depression; Divorce; Family Practice; Female; Hum | 1970 |
Differential response to chlorpromazine, imipramine, and placebo. A study of subgroups of hospitalized depressed patients.
Topics: Adolescent; Adult; Age Factors; Aged; Anxiety; Chlorpromazine; Clinical Trials as Topic; Depression; | 1970 |
Clinical and heuristic value of clinical drug research.
Topics: Affective Symptoms; Amitriptyline; Amphetamine; Butyrophenones; Child Behavior Disorders; Chlorproma | 1970 |
Comparative trial of a new mono-amine oxidase inhibitor in depression.
Topics: Clinical Trials as Topic; Constipation; Depression; Headache; Humans; Imipramine; Monoamine Oxidase | 1970 |
Depression associated with alcohol withdrawal. Imipramine therapy compared with placebo.
Topics: Adult; Alcoholism; Clinical Trials as Topic; Depression; Diarrhea; Humans; Imipramine; Male; Middle | 1971 |
[Double-blind study of the antidepressive drugs (noxiptilin-imipramine)].
Topics: Antidepressive Agents; Clinical Trials as Topic; Depression; Dibenzocycloheptenes; Humans; Imipramin | 1971 |
Measurement of drug effects in newly hospitalized depressives.
Topics: Adjustment Disorders; Amitriptyline; Antidepressive Agents; Clinical Trials as Topic; Depression; Ho | 1971 |
Multihospital controlled comparison of the therapeutic effects of four antidepressants.
Topics: Adult; Aged; Amitriptyline; Clinical Trials as Topic; Depression; Dibenzazepines; Dibenzothiepins; H | 1971 |
[Depressions treated with imipramine-N-oxide and imipramine. A controlled double-blind trial].
Topics: Adult; Age Factors; Aged; Clinical Trials as Topic; Depression; Female; Humans; Imipramine; Male; Mi | 1971 |
1. Improvement criteria in drug trials with neurotic patients.
Topics: Amobarbital; Chlordiazepoxide; Clinical Trials as Topic; Depression; Evaluation Studies as Topic; Hu | 1971 |
[Clinical trial with imipramine-N-oxide and amitriptyline-N-oxide].
Topics: Adult; Amitriptyline; Clinical Trials as Topic; Depression; Humans; Imipramine; Middle Aged | 1971 |
Clinical comparative evaluation of maprotiline, a new antidepressant drug. A multicentre study.
Topics: Adjustment Disorders; Adult; Aged; Amitriptyline; Analysis of Variance; Anthracenes; Antidepressive | 1971 |
Disturbance of the 24-hour rhythm in endogenous depression and the treatment of endogenous depression by sleep deprivation.
Topics: Adjustment Disorders; Adult; Age Factors; Amitriptyline; Antidepressive Agents; Blood Pressure; Circ | 1971 |
Chlorpromazine-chlordiazepoxide and chlorpromazine-imipramine treatment of newly hospitalized, acutely ill psychiatric patients.
Topics: Adult; Chlordiazepoxide; Chlorpromazine; Clinical Trials as Topic; Depression; Female; Humans; Imipr | 1966 |
Preclinical-clinical correlation of anti-depressant activity: controlled study of gamfexine and imipramine.
Topics: Adult; Antidepressive Agents; Clinical Trials as Topic; Depression; Female; Humans; Imipramine; Male | 1967 |
A comparison of melitracen and imipramine in treatment of depressed patients.
Topics: Adult; Anthracenes; Antidepressive Agents; Chronic Disease; Depression; Female; Humans; Imipramine; | 1969 |
Open trial evaluation of keto-imipramine.
Topics: Adult; Antidepressive Agents; Clinical Trials as Topic; Depression; Female; Humans; Imipramine; Male | 1971 |
Clinical trial of imidazoline (DH-524) as an anti-depressant.
Topics: Antidepressive Agents; Chronic Disease; Depression; Humans; Hypertension; Imidazoles; Imipramine | 1971 |
Double blind clinical study comparing doxepin and imipramine in depression.
Topics: Adolescent; Adult; Antidepressive Agents; Child; Clinical Trials as Topic; Depression; Dibenzoxepins | 1971 |
Ketipramine fumarate as compared to imipramine in depressed outpatients.
Topics: Adult; Aged; Amines; Clinical Trials as Topic; Depression; Dibenzazepines; Female; Fumarates; Humans | 1971 |
Concept identification and psychophysiological parameters in depressed schizophrenics as functions of imipramine and nialamide.
Topics: Concept Formation; Depression; Evaluation Studies as Topic; Form Perception; Galvanic Skin Response; | 1972 |
Role of antidepressants and neuroleptics in the treatment of depression.
Topics: Adult; Amitriptyline; Chronic Disease; Depression; Female; Humans; Imipramine; Male; Middle Aged; Pi | 1972 |
Depression and MHPG excretion. Response to dextroamphetamine and tricyclic antidepressants.
Topics: Adult; Affect; Antidepressive Agents; Brain Chemistry; Catechols; Depression; Desipramine; Dextroamp | 1972 |
EEC frequency analysis in the treatment with some antidepressive drugs (imipramine, amitriptyline, dibenzepine, dimethacrine).
Topics: Adult; Age Factors; Aged; Amitriptyline; Antidepressive Agents; Depression; Dibenzazepines; Electroe | 1971 |
Comparison of the effect of imipramine and desipramine on some symptoms of depressive illness.
Topics: Adult; Anorexia Nervosa; Anxiety; Clinical Trials as Topic; Depression; Desipramine; Humans; Imipram | 1965 |
Depression: dreams and defenses.
Topics: Adult; Clinical Trials as Topic; Defense Mechanisms; Depression; Dreams; Humans; Imipramine; Placebo | 1965 |
Clinical efficacy of chlorpromazine-procyclidine combination, imipramine and placebo in depressive disorders.
Topics: Chlorpromazine; Clinical Trials as Topic; Depression; Humans; Imipramine; Parasympatholytics; Placeb | 1965 |
A controlled trial with trimipramine, a new anti-depressant drug.
Topics: Antidepressive Agents; Clinical Trials as Topic; Depression; Humans; Imipramine; Placebos | 1965 |
Depression--an analysis of a follow-up study.
Topics: Amitriptyline; Clinical Trials as Topic; Depression; Female; Follow-Up Studies; Humans; Imipramine; | 1965 |
[Comparative evaluation of the antidepressive properties of opipramol, imipramine and placebo in neurotic depression].
Topics: Clinical Trials as Topic; Depression; Female; Humans; Imipramine; Opipramol; Placebos | 1966 |
Evaluation of treatment. Some lessons from control trials.
Topics: Antidepressive Agents; Clinical Trials as Topic; Depression; Female; Humans; Imipramine; Male; Phene | 1966 |
A double-blind comparison of a new antidepressant, protryptiline, with imipramine and amitryptiline.
Topics: Amitriptyline; Antidepressive Agents; Clinical Trials as Topic; Depression; Humans; Imipramine | 1966 |
[Depression and biochemistry--Results of Nuredal therapy].
Topics: Clinical Trials as Topic; Depression; Drug Incompatibility; Humans; Imipramine; Nialamide | 1966 |
Normetanephrine excretion and affective state in depressed patients treated with imipramine.
Topics: Affect; Bipolar Disorder; Clinical Trials as Topic; Depression; Female; Humans; Imipramine; Male; Mi | 1966 |
Importance of psychiatric diagnosis in prediction of clinical drug effects.
Topics: Antisocial Personality Disorder; Anxiety; Bipolar Disorder; Chlorpromazine; Clinical Trials as Topic | 1967 |
Imipramine (Tofranil vs. placebo in hospitalized psychotic depressives. (a comparison of patients' self-ratings, psychiatrists' ratings and psychological test scores).
Topics: Clinical Trials as Topic; Depression; Female; Humans; Imipramine; Male; Middle Aged; Placebos; Psych | 1966 |
The speed of action of desipramine: a controlled trial.
Topics: Adolescent; Adult; Clinical Trials as Topic; Depression; Desipramine; Female; Humans; Imipramine; Mi | 1967 |
[The treatment of endogenous depression with monochlorimipramin].
Topics: Amitriptyline; Antidepressive Agents; Bipolar Disorder; Chlordiazepoxide; Clinical Trials as Topic; | 1967 |
Observer bias in drug trial.
Topics: Amitriptyline; Clinical Trials as Topic; Depression; Humans; Imipramine; Research | 1966 |
Drugs and dreams 3. The effects of imipramine on the dreams of depressed patients.
Topics: Anxiety; Depression; Dreams; Eye Movements; Homosexuality; Hospitalization; Hostility; Humans; Imipr | 1968 |
1047 other studies available for imipramine and Depression
| Article | Year |
|---|---|
New bicyclic antidepressant agent. Synthesis and activity of napactadine and related compounds.
Topics: Aggression; Amidines; Animals; Blepharoptosis; Cerebral Cortex; Chemical Phenomena; Chemistry; Depre | 1985 |
Antidepressant-like profile of action of two 4-amine derivatives of 10,11-dihydro-5H-dibenzo [a,d] cycloheptane in mice evaluated in the forced swimming test.
Topics: Amines; Animals; Antidepressive Agents; Cycloheptanes; Depression; Disease Models, Animal; Exercise | 2007 |
Design and synthesis of novel hydantoin-containing melanin-concentrating hormone receptor antagonists.
Topics: Animals; Chemistry, Pharmaceutical; Depression; Disease Models, Animal; Drug Design; Feeding Behavio | 2007 |
Synthesis and serotonin receptor activity of the arylpiperazine alkyl/propoxy derivatives of new azatricycloundecanes.
Topics: Animals; Antidepressive Agents; Anxiety; Depression; Mice; Receptor, Serotonin, 5-HT1A; Receptor, Se | 2009 |
In vitro structure-activity relationships of aplysinopsin analogs and their in vivo evaluation in the chick anxiety-depression model.
Topics: Animals; Antidepressive Agents; Anxiety; Behavior, Animal; Chickens; Depression; Disease Models, Ani | 2013 |
Design and synthesis of new series of coumarin-aminopyran derivatives possessing potential anti-depressant-like activity.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Coumarins; Depression; Dose-Response Relationship, | 2015 |
Synthesis, structure-activity relationships and biological evaluation of 4,5,6,7-tetrahydropyrazolopyrazines as metabotropic glutamate receptor 5 negative allosteric modulators.
Topics: Allosteric Regulation; Animals; Antidepressive Agents; Brain; Depression; Disease Models, Animal; Ha | 2016 |
Novel aryl piperazines for alleviation of 'andropause' associated prostatic disorders and depression.
Topics: Androgen Antagonists; Andropause; Animals; Cell Line; Depression; Down-Regulation; Humans; Male; Mol | 2017 |
Novel multitarget 5-arylidenehydantoins with arylpiperazinealkyl fragment: Pharmacological evaluation and investigation of cytotoxicity and metabolic stability.
Topics: Animals; Antidepressive Agents; Depression; Disease Models, Animal; Humans; Receptors, Serotonin; St | 2019 |
Discovery and Development of 3-(6-Chloropyridine-3-yloxymethyl)-2-azabicyclo[3.1.0]hexane Hydrochloride (SUVN-911): A Novel, Potent, Selective, and Orally Active Neuronal Nicotinic Acetylcholine α4β2 Receptor Antagonist for the Treatment of Depression.
Topics: Administration, Oral; Animals; Antidepressive Agents; Bridged Bicyclo Compounds; Depression; Halogen | 2020 |
Synthesis and biological evaluation of imidazoline derivatives as potential CNS and CVS agents.
Topics: Animals; Antihypertensive Agents; Central Nervous System Agents; Depression; Female; Hypertension; I | 2020 |
Investigation of Cochlospermum religiosum leaves for antidepressant and anxiolytic activities and its synergistic effect with imipramine and fluoxetine.
Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Behavior, Animal; Bixaceae; Depression; Fluoxet | 2022 |
Decreased sensitivity to antidepressant drugs in Wistar Hannover rats submitted to two animal models of depression.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Depression; Escitalopram; Fluoxetine; Imipramine; | 2023 |
Methanolic Extract of
Topics: Amaranthaceae; Animals; Antidepressive Agents; Behavior, Animal; Brain-Derived Neurotrophic Factor; | 2022 |
Methanolic Extract of
Topics: Amaranthaceae; Animals; Antidepressive Agents; Behavior, Animal; Brain-Derived Neurotrophic Factor; | 2022 |
Methanolic Extract of
Topics: Amaranthaceae; Animals; Antidepressive Agents; Behavior, Animal; Brain-Derived Neurotrophic Factor; | 2022 |
Methanolic Extract of
Topics: Amaranthaceae; Animals; Antidepressive Agents; Behavior, Animal; Brain-Derived Neurotrophic Factor; | 2022 |
Increased Brain-Derived Neurotrophic Factor and Hippocampal Dendritic Spine Density Are Associated with the Rapid Antidepressant-like Effect of Iron-citalopram and Iron-Imipramine Combinations in Mice.
Topics: Animals; Antidepressive Agents; Brain-Derived Neurotrophic Factor; Citalopram; Deferoxamine; Dendrit | 2023 |
The effect of maternal separation stress-induced depression on ovarian reserve in Sprague Dawley Rats: The possible role of imipramine and agmatine through a mTOR signal pathway.
Topics: Agmatine; Animals; Depression; Female; Imipramine; Maternal Deprivation; Ovarian Reserve; Rats; Rats | 2023 |
Involvement of indoleamine 2, 3-dioxygenase (IDO) and brain-derived neurotrophic factor (BDNF) in the neuroprotective mechanisms of ferulic acid against depressive-like behaviour.
Topics: Animals; Brain-Derived Neurotrophic Factor; Cytokines; Depression; Imipramine; Indoleamine-Pyrrole 2 | 2023 |
Neuroprotective effects of goji berry (Lycium barbarum L.) polysaccharides on depression-like behavior in ovariectomized rats: behavioral and biochemical evidence.
Topics: Animals; Brain-Derived Neurotrophic Factor; Depression; Female; Imipramine; Lycium; Malondialdehyde; | 2023 |
A comparative analysis of depressive-like behavior: Exploring sex-related differences and insights.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Corticosterone; Depression; Disease Models, Animal | 2023 |
Rapid antidepressant actions of imipramine potentiated by zinc through PKA-dependented regulation of mTOR and CREB signaling.
Topics: Animals; Antidepressive Agents; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Pr | 2019 |
MicroRNA profiling identifies a novel compound with antidepressant properties.
Topics: Animals; Antidepressive Agents; Brain Injuries, Traumatic; Computational Biology; Depression; Diseas | 2019 |
Fish Oil, but Not Olive Oil, Ameliorates Depressive-Like Behavior and Gut Microbiota Dysbiosis in Rats under Chronic Mild Stress.
Topics: Animals; Bacteria; Behavior, Animal; Depression; Disease Models, Animal; Dysbiosis; Fish Oils; Gastr | 2019 |
Neonatal Immune Activation May Provoke Long-term Depressive Attributes.
Topics: Animals; Animals, Newborn; Corticosterone; Depression; Depressive Disorder; Disease Models, Animal; | 2019 |
Antidepressant-like effects of fish, krill oils and Vit B12 against exposure to stress environment in mice models: current status and pilot study.
Topics: Animals; Antidepressive Agents; Antioxidants; Depression; Depressive Disorder; Dietary Proteins; Dis | 2019 |
Enhanced conditioning of adverse memories in the mouse modified swim test is associated with neuroinflammatory changes - Effects that are susceptible to antidepressants.
Topics: Animals; Antidepressive Agents, Tricyclic; Brain; Depression; Disease Models, Animal; Encephalitis; | 2020 |
mGluR5 mediates ketamine antidepressant response in susceptible rats exposed to prenatal stress.
Topics: Animals; Antidepressive Agents; Depression; Fluoxetine; Imipramine; Ketamine; Rats | 2020 |
Imipramine exerts antidepressant-like effects in chronic stress models of depression by promoting CRTC1 expression in the mPFC.
Topics: Animals; Antidepressive Agents; Depression; Disease Models, Animal; Female; Imipramine; Male; Mice; | 2020 |
Indomethacin, a nonselective cyclooxygenase inhibitor, does not interact with MTEP in antidepressant-like activity, as opposed to imipramine in CD-1 mice.
Topics: Animals; Antidepressive Agents; Cyclooxygenase Inhibitors; Depression; Drug Interactions; Hindlimb S | 2020 |
Jiao-Tai-Wan Ameliorates Depressive-Like Behavior through the A
Topics: Animals; Behavior, Animal; Depression; Depressive Disorder; Disease Models, Animal; Drugs, Chinese H | 2020 |
Antidepressant treatment is associated with epigenetic alterations of Homer1 promoter in a mouse model of chronic depression.
Topics: Animals; Antidepressive Agents; Depression; Disease Models, Animal; Epigenesis, Genetic; Homer Scaff | 2021 |
Ketamine reversed short-term memory impairment and depressive-like behavior in animal model of Parkinson's disease.
Topics: Animals; Behavior, Animal; Depression; Disease Models, Animal; Imipramine; Ketamine; Male; Memory, S | 2021 |
Proteome profile of telencephalon associates attenuated neurogenesis with chronic stress induced mood disorder phenotypes in zebrafish model.
Topics: Affect; Animals; Antidepressive Agents; Anxiety; Cell Proliferation; Depression; Disease Models, Ani | 2021 |
Imipramine attenuates anxiety- and depressive-like effects of acute and prolonged ethanol-abstinence in male rats by modulating SERT and GR expression in the dorsal hippocampus.
Topics: Alcohol Abstinence; Animals; Anxiety; Behavior, Animal; Depression; Hippocampus; Imipramine; Male; R | 2021 |
Antidepressants Differentially Regulate Intracellular Signaling from α1-Adrenergic Receptor Subtypes In Vitro.
Topics: Animals; Antidepressive Agents; Citalopram; Depression; Desipramine; Fluoxetine; Gene Expression Reg | 2021 |
Disturbance of prefrontal cortical myelination in olfactory bulbectomized mice is associated with depressive-like behavior.
Topics: Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Cell Count; Demyelinating Diseases; Dep | 2021 |
Synergistic effect between imipramine and citicoline upon induction of analgesic and antidepressant effects in mice.
Topics: Analgesics; Animals; Antidepressive Agents, Tricyclic; Cytidine Diphosphate Choline; Depression; Dis | 2021 |
Ginsenoside Rb1 induces a pro-neurogenic microglial phenotype via PPARγ activation in male mice exposed to chronic mild stress.
Topics: Animals; Behavior, Animal; Cytokines; Depression; Ginsenosides; Hippocampus; Imipramine; Male; Mice; | 2021 |
Basal prolactin levels in rat plasma correlates with response to antidepressant treatment in animal model of depression.
Topics: Anhedonia; Animals; Antidepressive Agents; Depression; Imipramine; Male; Prolactin; Rats; Stress, Ps | 2017 |
Antidepressant-like effect of 1,2,3,4-tetrahydroisoquinoline and its methyl derivative in animal models of depression.
Topics: Animals; Antidepressive Agents; Brain; Chromatography, High Pressure Liquid; Depression; Disease Mod | 2017 |
Role of cortical alpha-2 adrenoceptors in alcohol withdrawal-induced depression and tricyclic antidepressants.
Topics: Animals; Antidepressive Agents, Tricyclic; Blood Alcohol Content; Depression; Disease Models, Animal | 2017 |
Evaluation of the effectiveness of chronic antidepressant drug treatments in the hippocampal mitochondria - A proteomic study in an animal model of depression.
Topics: 14-3-3 Proteins; Animals; Antidepressive Agents; Cathepsin D; COP9 Signalosome Complex; Depression; | 2017 |
Decreased Prostaglandin D2 Levels in Major Depressive Disorder Are Associated with Depression-Like Behaviors.
Topics: Adolescent; Adult; Animals; Antidepressive Agents, Tricyclic; Antioxidants; Brain; Chromatography, L | 2017 |
Methyl jasmonate attenuated lipopolysaccharide-induced depressive-like behaviour in mice.
Topics: Acetates; Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Behavior, Animal; Brain; | 2017 |
Imipramine for multiple functional somatic syndromes.
Topics: Depression; Double-Blind Method; Humans; Imipramine; Somatoform Disorders; Syndrome | 2017 |
The Neurotensin NTS
Topics: Animals; Antidepressive Agents; Depression; Disease Models, Animal; Drug Evaluation, Preclinical; Hu | 2017 |
SIRT2 inhibition reverses anhedonia in the VGLUT1+/- depression model.
Topics: Anhedonia; Animals; Antidepressive Agents; Depression; Disease Models, Animal; Glutamic Acid; Histon | 2017 |
Elucidating the functions of brain GSK3α: Possible synergy with GSK3β upregulation and reversal by antidepressant treatment in a mouse model of depressive-like behaviour.
Topics: Animals; Antidepressive Agents; Brain; Depression; Disease Models, Animal; Glycogen Synthase Kinase | 2017 |
Differential effects of imipramine and CORT118335 (Glucocorticoid receptor modulator/mineralocorticoid receptor antagonist) on brain-endocrine stress responses and depression-like behavior in female rats.
Topics: Adrenocorticotropic Hormone; Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Behav | 2018 |
The hemoglobin derived peptide LVV-hemorphin-7 evokes behavioral effects mediated by oxytocin receptors.
Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Behavior, Animal; Depression; Diazepam | 2017 |
Garcinia mangostana Linn displays antidepressant-like and pro-cognitive effects in a genetic animal model of depression: a bio-behavioral study in the Flinders Sensitive Line rat.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Cognition; Depression; Disease Models, Animal; Gar | 2018 |
Repeated treatment with nitric oxide synthase inhibitor attenuates learned helplessness development in rats and increases hippocampal BDNF expression.
Topics: Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Brain-Derived Neurotrophic Factor; Depr | 2018 |
Social stress induces neurovascular pathology promoting depression.
Topics: Adrenergic Uptake Inhibitors; Animals; Anxiety; Behavior, Animal; Blood-Brain Barrier; Claudin-5; De | 2017 |
Hippocampal extracellular matrix alterations contribute to cognitive impairment associated with a chronic depressive-like state in rats.
Topics: Animals; CA1 Region, Hippocampal; Chondroitin ABC Lyase; Chondroitin Sulfate Proteoglycans; Chronic | 2017 |
Involvement of the dopaminergic system in the antidepressant-like effect of the lectin isolated from the red marine alga Solieria filiformis in mice.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Depression; Dopamine; Dopamine Agents; Dopaminergi | 2018 |
Effects of ketamine on vocal impairment, gait changes, and anhedonia induced by bilateral 6-OHDA infusion into the substantia nigra pars compacta in rats: Therapeutic implications for Parkinson's disease.
Topics: Anhedonia; Animals; Depression; Disease Models, Animal; Gait; Imipramine; Ketamine; Male; Nerve Dege | 2018 |
Mitochondrial proteomics investigation of frontal cortex in an animal model of depression: Focus on chronic antidepressant drugs treatment.
Topics: Animals; Antidepressive Agents; Depression; Depressive Disorder; Disease Models, Animal; Female; Flu | 2018 |
Zanthoxylum alatum abrogates lipopolysaccharide-induced depression-like behaviours in mice by modulating neuroinflammation and monoamine neurotransmitters in the hippocampus.
Topics: Animals; Anti-Inflammatory Agents; Antidepressive Agents; Behavior, Animal; Biogenic Monoamines; Bra | 2018 |
Regulation of somatostatin receptor 2 in the context of antidepressant treatment response in chronic mild stress in rat.
Topics: Anhedonia; Animals; Antidepressive Agents; Autoradiography; Brain; Depression; Disease Models, Anima | 2018 |
DPCPX, a selective adenosine A1 receptor antagonist, enhances the antidepressant-like effects of imipramine, escitalopram, and reboxetine in mice behavioral tests.
Topics: Adenosine A1 Receptor Antagonists; Animals; Antidepressive Agents; Brain; Citalopram; Depression; Dr | 2018 |
Validation of chronic mild stress in the Wistar-Kyoto rat as an animal model of treatment-resistant depression.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Citalopram; Depression; Depressive Disorder; Depre | 2019 |
Imipramine treatment reverses depressive- and anxiety-like behaviors, normalize adrenocorticotropic hormone, and reduces interleukin-1β in the brain of rats subjected to experimental periapical lesion.
Topics: Adrenocorticotropic Hormone; Animals; Antidepressive Agents, Tricyclic; Anxiety; Behavior, Animal; B | 2019 |
Long-lasting antidepressant-like activity of the GPR39 zinc receptor agonist TC-G 1008.
Topics: Animals; Antidepressive Agents; Brain-Derived Neurotrophic Factor; Chlorides; Depression; Dizocilpin | 2019 |
Behavioral and metabolic effects of S-adenosylmethionine and imipramine in the Flinders Sensitive Line rat model of depression.
Topics: Animals; Antidepressive Agents; Brain; Cognition; Depression; Depressive Disorder; Disease Models, A | 2019 |
Maternal Flavonoids Intake Reverts Depression-Like Behaviour in Rat Female Offspring.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Depression; Diet; Disaccharides; Drug Interactions | 2019 |
Insulin-stimulated mTOR activation in peripheral blood mononuclear cells associated with early treatment response to lithium augmentation in rodent model of antidepressant-resistance.
Topics: Animals; Antidepressive Agents, Tricyclic; Depression; Imipramine; Insulin; Leukocytes, Mononuclear; | 2019 |
New evidence for refinement of anesthetic choice in procedures preceding the forced swimming test and the elevated plus-maze.
Topics: Anesthetics, General; Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Behavior, Animal | 2019 |
The effect of depressive-like behavior and antidepressant therapy on social behavior and hierarchy in rats.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Depression; Depressive Disorder; Disease Models, A | 2019 |
Interaction of the immune-inflammatory and the kynurenine pathways in rats resistant to antidepressant treatment in model of depression.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Cell Proliferation; Cerebral Cortex; Cytokines; De | 2019 |
Behavioural effects of inhalation exposure to dizocilpine (MK-801) in mice.
Topics: Animals; Behavior, Animal; Depression; Dizocilpine Maleate; Drug Administration Routes; Imipramine; | 2019 |
Antidepressants with different mechanisms of action show different chronopharmacological profiles in the tail suspension test in mice.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Bupropion; Circadian Rhythm; Depression; Dopamine; | 2019 |
Modulation of the neurotransmitter systems through the anti-inflammatory and antidepressant-like effects of squalene from Aurantiochytrium sp.
Topics: Animals; Anti-Inflammatory Agents; Antidepressive Agents; Behavior, Animal; Brain; Brain-Derived Neu | 2019 |
Neuronal life or death linked to depression treatment: the interplay between drugs and their stress-related outcomes relate to single or combined drug therapies.
Topics: Amitriptyline; Animals; Antidepressive Agents; Cell Cycle Checkpoints; Depression; Fluoxetine; Hippo | 2019 |
Depression-like behavior is dependent on age in male SAMP8 mice.
Topics: Aging; Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Cerebral Cortex; Depression; Dis | 2013 |
Effect of newly synthesized 1,2,4-triazino[5,6-b]indole-3-thione derivatives on olfactory bulbectomy induced depression in rats.
Topics: Acetamides; Acetanilides; Animals; Antidepressive Agents; Behavior, Animal; Depression; Disease Mode | 2012 |
Novel systemically active galanin receptor 2 ligands in depression-like behavior.
Topics: Amino Acid Sequence; Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Binding, Competiti | 2013 |
Imipramine-induced c-Fos expression in the medial prefrontal cortex is decreased in the ACTH-treated rats.
Topics: Adrenocorticotropic Hormone; Amygdala; Animals; Antidepressive Agents, Tricyclic; Dentate Gyrus; Dep | 2013 |
Differential effects of nomifensine and imipramine on motivated behavior in the runway model of intracranial self-stimulation.
Topics: Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents; Behavior, Animal; Depression; Dopamine | 2013 |
The effect of GABAmimetics on the duration of immobility in the forced swim test in albino mice.
Topics: Alprazolam; Animals; Depression; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; | 2014 |
Antidepressant properties of aqueous macerate from Gladiolus dalenii corms.
Topics: 2-Amino-5-phosphonovalerate; Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents; Depressio | 2014 |
Behavioural, metabolic, and endothelial effects of the TNF-α suppressor thalidomide on rats subjected to chronic mild stress and fed an atherogenic diet.
Topics: Animals; Antidepressive Agents, Tricyclic; Aorta, Thoracic; Atherosclerosis; Chronic Disease; Depres | 2014 |
[Study on antidepressant effect of kuanxinjieyutang combined aerobic exercise].
Topics: Animals; Antidepressive Agents; Brain; Brain-Derived Neurotrophic Factor; Combined Modality Therapy; | 2013 |
Pramipexole but not imipramine or fluoxetine reverses the "depressive-like" behaviour in a rat model of preclinical stages of Parkinson's disease.
Topics: Animals; Antidepressive Agents; Benzothiazoles; Depression; Disease Models, Animal; Dopamine Agonist | 2014 |
The depressogenic-like effect of acute and chronic treatment with dexamethasone and its influence on the activity of antidepressant drugs in the forced swim test in adult mice.
Topics: Amitriptyline; Animals; Antidepressive Agents; Citalopram; Depression; Dexamethasone; Dose-Response | 2014 |
GLP-1 receptor agonist liraglutide reverses long-term atypical antipsychotic treatment associated behavioral depression and metabolic abnormalities in rats.
Topics: Animals; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Benzodiazepines; Body Weight; Chole | 2015 |
Disrupted MEK/ERK signaling in the medial orbital cortex and dorsal endopiriform nuclei of the prefrontal cortex in a chronic restraint stress mouse model of depression.
Topics: Animals; Antidepressive Agents; Chronic Disease; Depression; Imipramine; Male; Mice, Inbred C57BL; M | 2014 |
Lipopolysaccharide repeated challenge followed by chronic mild stress protocol introduces a combined model of depression in rats: reversibility by imipramine and pentoxifylline.
Topics: Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Corticosterone; Depression; Disease Mod | 2014 |
Effects of N-acetylcysteine and imipramine in a model of acute rhythm disruption in BALB/c mice.
Topics: Acetylcysteine; Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Circadian Rhythm; Corti | 2015 |
Chronic but not acute antidepresant treatment alters serum zinc/copper ratio under pathological/zinc-deficient conditions in mice.
Topics: Animals; Antidepressive Agents; Bupropion; Citalopram; Copper; Depression; Disease Models, Animal; I | 2014 |
The effects of ifenprodil on the activity of antidepressant drugs in the forced swim test in mice.
Topics: Animals; Antidepressive Agents; Depression; Disease Models, Animal; Drug Synergism; Fluoxetine; Imip | 2014 |
Antidepressant-like effect of atorvastatin in the forced swimming test in mice: the role of PPAR-gamma receptor and nitric oxide pathway.
Topics: Anilides; Animals; Antidepressive Agents; Atorvastatin; Depression; Heptanoic Acids; Hydroxymethylgl | 2014 |
Memantine prevents "bipolar-like" behavior induced by chronic treatment with imipramine in rats.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Bipolar Disorder; Depression; Imipramine; Male; Me | 2015 |
Imipramine protects against the deleterious effects of chronic corticosterone on depression-like behavior, hippocampal reelin expression, and neuronal maturation.
Topics: Animals; Anti-Inflammatory Agents; Antidepressive Agents, Tricyclic; Cell Adhesion Molecules, Neuron | 2015 |
Metabolomic identification of biochemical changes induced by fluoxetine and imipramine in a chronic mild stress mouse model of depression.
Topics: Animals; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Chronic Disease | 2015 |
Involvement of AMPA receptors in the antidepressant-like effects of dextromethorphan in mice.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Depression; Depressive Disorder; Dextromethorphan; | 2015 |
Study of antidepressant drugs in GPR39 (zinc receptor⁻/⁻) knockout mice, showing no effect of conventional antidepressants, but effectiveness of NMDA antagonists.
Topics: Animals; Antidepressive Agents; Citalopram; Depression; Dizocilpine Maleate; Excitatory Amino Acid A | 2015 |
Agmatine, by Improving Neuroplasticity Markers and Inducing Nrf2, Prevents Corticosterone-Induced Depressive-Like Behavior in Mice.
Topics: Agmatine; Anhedonia; Animals; Antidepressive Agents; Astrocytes; Behavior, Animal; Biomarkers; Corti | 2016 |
Chronic imipramine treatment differentially alters the brain and plasma amino acid metabolism in Wistar and Wistar Kyoto rats.
Topics: Amino Acids; Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Body Weight; Brain; Depres | 2015 |
The positive effect on ketamine as a priming adjuvant in antidepressant treatment.
Topics: Animals; Antidepressive Agents; Anxiety; Aspartic Acid; Behavior, Animal; Brain; Depression; Depress | 2015 |
The effect of imipramine, ketamine, and zinc in the mouse model of depression.
Topics: Animals; Antidepressive Agents, Tricyclic; Depression; Dexamethasone; Dose-Response Relationship, Dr | 2015 |
The loss of NDRG2 expression improves depressive behavior through increased phosphorylation of GSK3β.
Topics: Adaptor Proteins, Signal Transducing; Affect; Animals; Antidepressive Agents, Tricyclic; Cell Hypoxi | 2015 |
Increased Signaling via Adenosine A1 Receptors, Sleep Deprivation, Imipramine, and Ketamine Inhibit Depressive-like Behavior via Induction of Homer1a.
Topics: Animals; Carrier Proteins; Depression; Homer Scaffolding Proteins; Humans; Imipramine; Ketamine; Mic | 2015 |
Antidepressant-like activity of plumbagin in unstressed and stressed mice.
Topics: Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Antioxidants; Behavior, Animal; Br | 2015 |
Antidepressant-like effects of methanolic extract of Bacopa monniera in mice.
Topics: Animals; Antidepressive Agents; Bacopa; Behavior, Animal; Depression; Disease Models, Animal; Imipra | 2015 |
IL-4/10 prevents stress vulnerability following imipramine discontinuation.
Topics: Animals; Antidepressive Agents, Tricyclic; Anxiety; Behavior, Animal; Depression; Electroshock; Expl | 2015 |
Combined use of spatial restraint stress and middle cerebral artery occlusion is a novel model of post-stroke depression in mice.
Topics: Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Body Weight; Brain; Brain-Derived Neuro | 2015 |
Honokiol abrogates chronic restraint stress-induced cognitive impairment and depressive-like behaviour by blocking endoplasmic reticulum stress in the hippocampus of mice.
Topics: Animals; Behavior, Animal; Biphenyl Compounds; Brain-Derived Neurotrophic Factor; Cognition Disorder | 2016 |
Tipepidine, a non-narcotic antitussive, exerts an antidepressant-like effect in the forced swimming test in adrenocorticotropic hormone-treated rats.
Topics: Adrenocorticotropic Hormone; Animals; Antidepressive Agents; Benzazepines; Depression; Disease Model | 2016 |
Testosterone has antidepressant-like efficacy and facilitates imipramine-induced neuroplasticity in male rats exposed to chronic unpredictable stress.
Topics: Animals; Antidepressive Agents; Chronic Disease; Corticosterone; Dentate Gyrus; Depression; Disease | 2016 |
Alterations in behavioral responses to dopamine agonists in olfactory bulbectomized mice: relationship to changes in the striatal dopaminergic system.
Topics: Animals; Apomorphine; Corpus Striatum; Depression; Disease Models, Animal; Dopamine; Dopamine Agonis | 2016 |
[Effects of ketamine, imipramine, and their combination on depression-like behaviors in Wistar Kyoto rats].
Topics: Animals; Brain; Depression; Depressive Disorder; Disease Models, Animal; Down-Regulation; Imipramine | 2016 |
Epigenetic regulation of BDNF in the learned helplessness-induced animal model of depression.
Topics: Animals; Antidepressive Agents; Brain-Derived Neurotrophic Factor; Butyric Acid; Depression; Disease | 2016 |
Traxoprodil, a selective antagonist of the NR2B subunit of the NMDA receptor, potentiates the antidepressant-like effects of certain antidepressant drugs in the forced swim test in mice.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Citalopram; Depression; Disease Models, Animal; Ex | 2016 |
The effect of chronic tianeptine administration on the brain mitochondria: direct links with an animal model of depression.
Topics: Animals; Anxiety; Behavior, Animal; Brain; Depression; Disease Models, Animal; Electrophoresis, Gel, | 2016 |
Effect of acupuncture stimulation on rats with depression induced by water-immersion stress.
Topics: Acupuncture Therapy; Animals; Antidepressive Agents; Depression; Imipramine; Immersion; Male; Rats, | 2016 |
Zinc and imipramine reverse the depression-like behavior in mice induced by chronic restraint stress.
Topics: Animals; Brain-Derived Neurotrophic Factor; Corticosterone; CREB-Binding Protein; Depression; Depres | 2016 |
Hippocampal Sirtuin 1 Signaling Mediates Depression-like Behavior.
Topics: Animals; Antidepressive Agents, Tricyclic; Benzamides; Dendrites; Dentate Gyrus; Depression; Disease | 2016 |
Comparison of the Efficiency of Adeprophen and Antidepressants of Various Groups on the Model of Reserpine-Induced Depression in Rats.
Topics: Adenine; Amitriptyline; Animals; Antidepressive Agents; Behavior, Animal; Depression; Disease Models | 2016 |
Memantine improves memory impairment and depressive-like behavior induced by amphetamine withdrawal in rats.
Topics: Amphetamine; Amphetamine-Related Disorders; Animals; Antidepressive Agents; Central Nervous System S | 2016 |
Fourteen-day administration of corticosterone may induce detrusor overactivity symptoms.
Topics: Analysis of Variance; Animals; Antidepressive Agents, Tricyclic; Corticosterone; Depression; Disease | 2016 |
Evidence for the involvement of neuropeptide Y in the antidepressant effect of imipramine in type 2 diabetes.
Topics: Animals; Antidepressive Agents, Tricyclic; Arginine; Blood Glucose; Central Amygdaloid Nucleus; Depr | 2016 |
Antidepressant imipramine diminishes stress-induced inflammation in the periphery and central nervous system and related anxiety- and depressive- like behaviors.
Topics: Animals; Antidepressive Agents, Tricyclic; Anxiety; Behavior, Animal; Corticosterone; Depression; Im | 2016 |
The effect of Schisandra chinensis extracts on depression by noradrenergic, dopaminergic, GABAergic and glutamatergic systems in the forced swim test in mice.
Topics: Adrenergic Neurons; Animals; Antidepressive Agents; Depression; Disease Models, Animal; Dopaminergic | 2016 |
Influence of Genetic Polymorphisms and Concomitant Anxiolytic Doses on Antidepressant Maintenance Doses in Japanese Patients with Depression.
Topics: Adult; Aged; Aged, 80 and over; Anti-Anxiety Agents; Antidepressive Agents; Asian People; Brain-Deri | 2016 |
Nucleus accumbens deep-brain stimulation efficacy in ACTH-pretreated rats: alterations in mitochondrial function relate to antidepressant-like effects.
Topics: Adenosine Triphosphate; Adrenocorticotropic Hormone; Affect; Animals; Bipolar Disorder; Deep Brain S | 2016 |
Depression-Like Adult Behaviors may be a Long-Term Result of Experimental Pneumococcal Meningitis in Wistar Rats Infants.
Topics: Animals; Behavior, Animal; Brain; Brain-Derived Neurotrophic Factor; Corticosterone; Depression; Dis | 2016 |
Hippocampal MicroRNA-124 Enhances Chronic Stress Resilience in Mice.
Topics: Animals; Antidepressive Agents; Depression; Disease Models, Animal; Fluoroquinolones; Food Preferenc | 2016 |
Antidepressant drugs can modify cytotoxic action of temozolomide.
Topics: Antidepressive Agents; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Division; | 2017 |
The effects of Sceletium tortuosum (L.) N.E. Br. extract fraction in the chick anxiety-depression model.
Topics: Animals; Antidepressive Agents; Anxiety; Chickens; Depression; Disease Models, Animal; Imipramine; M | 2016 |
Lentinan produces a robust antidepressant-like effect via enhancing the prefrontal Dectin-1/AMPA receptor signaling pathway.
Topics: Adjuvants, Immunologic; Animals; Antidepressive Agents, Tricyclic; Benzodiazepines; Depression; Dise | 2017 |
The α2C-adrenoceptor antagonist, ORM-10921, exerts antidepressant-like effects in the Flinders Sensitive Line rat.
Topics: Adrenergic alpha-2 Receptor Antagonists; Animals; Antidepressive Agents; Behavior, Animal; Benzofura | 2017 |
Antidepressant, anxiolytic and procognitive effects of subacute and chronic ketamine in the chronic mild stress model of depression.
Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Depression; Discrimination Learning; Disease Mo | 2017 |
A mixed glucocorticoid/mineralocorticoid receptor modulator dampens endocrine and hippocampal stress responsivity in male rats.
Topics: Amygdala; Animals; Corticosterone; Depression; Hippocampus; Hormones; Imipramine; Male; Motor Activi | 2017 |
Modelling the anxiety-depression continuum in chicks.
Topics: Animals; Animals, Newborn; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Chickens; Chlordiaze | 2009 |
[In memory of Roland Kuhn (1912-2005) and 50 years of imipramine].
Topics: Antidepressive Agents, Tricyclic; Depression; History, 20th Century; Humans; Imipramine; Psychiatry; | 2008 |
Mouse strain differences in the unpredictable chronic mild stress: a four-antidepressant survey.
Topics: Animals; Animals, Outbred Strains; Antidepressive Agents; Antidepressive Agents, Second-Generation; | 2008 |
Potential antidepressant properties of cysteamine on hippocampal BDNF levels and behavioral despair in mice.
Topics: Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Brain-Derived Neurotrophic Factor; | 2008 |
Effects of age on susceptibility to the induction of depressive behavior and imipramine in rats.
Topics: Age Factors; Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Brain-Derived Neurotrophic | 2008 |
SSR149415, a non-peptide vasopressin V1b receptor antagonist, has long-lasting antidepressant effects in the olfactory bulbectomy-induced hyperactivity depression model.
Topics: Animals; Antidepressive Agents; Antidiuretic Hormone Receptor Antagonists; Behavior, Animal; Depress | 2009 |
Multifaceted strain-specific effects in a mouse model of depression and of antidepressant reversal.
Topics: Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Body Weight; Depression; Explorato | 2008 |
Forkhead box, class O transcription factors in brain: regulation and behavioral manifestation.
Topics: Affect; Analysis of Variance; Animals; Antidepressive Agents, Tricyclic; Anxiety; Behavior, Animal; | 2009 |
PUFA induce antidepressant-like effects in parallel to structural and molecular changes in the hippocampus.
Topics: alpha-Linolenic Acid; Animals; Antidepressive Agents, Tricyclic; Anxiety; Behavior, Animal; Brain; B | 2009 |
The mood-improving actions of antidepressants do not depend on neurogenesis but are associated with neuronal remodeling.
Topics: Affect; Analysis of Variance; Animals; Antidepressive Agents; Antidiuretic Hormone Receptor Antagoni | 2009 |
Behavioral profile of P2X7 receptor knockout mice in animal models of depression and anxiety: relevance for neuropsychiatric disorders.
Topics: Analysis of Variance; Animals; Antidepressive Agents, Tricyclic; Anxiety; Behavior, Animal; Depressi | 2009 |
Gene expression profiling reveals complex changes in the olfactory bulbectomy model of depression after chronic treatment with antidepressants.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Benzamides; Cerebral Cortex; Cluster Analysis; Dep | 2008 |
Optimal designs for empirical bayes estimators of individual linear and quadratic growth curves in linear mixed models.
Topics: Antidepressive Agents, Tricyclic; Bayes Theorem; Depression; Humans; Imipramine; Linear Models; Rese | 2009 |
Antidepressant-like effects of melatonin in the mouse chronic mild stress model.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Chronic Disease; Circadian Rhythm; Corticosterone; | 2009 |
Neuropeptide Y modulates the antidepressant activity of imipramine in olfactory bulbectomized rats: involvement of NPY Y1 receptors.
Topics: Analysis of Variance; Animals; Antidepressive Agents, Tricyclic; Arginine; Behavior, Animal; Depress | 2009 |
Conditional ablation and recovery of forebrain neurogenesis in the mouse.
Topics: Animals; Antidepressive Agents, Tricyclic; Antiviral Agents; Cell Count; Cell Proliferation; Cells, | 2009 |
Imipramine treatment and resiliency exhibit similar chromatin regulation in the mouse nucleus accumbens in depression models.
Topics: Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Chromatin; Chromatin Immunoprecipitatio | 2009 |
Acute harmine administration induces antidepressive-like effects and increases BDNF levels in the rat hippocampus.
Topics: Analysis of Variance; Animals; Antidepressive Agents; Brain-Derived Neurotrophic Factor; Depression; | 2009 |
Depressive-like parameters in sepsis survivor rats.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Analysis of Variance; Animals; Antidepressive Agents, T | 2010 |
Chronic treatment with the selective NOP receptor antagonist [Nphe 1, Arg 14, Lys 15]N/OFQ-NH 2 (UFP-101) reverses the behavioural and biochemical effects of unpredictable chronic mild stress in rats.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Depression; Disease Models, Animal; Dose-Response | 2009 |
Effect of acute administration of ketamine and imipramine on creatine kinase activity in the brain of rats.
Topics: Animals; Antidepressive Agents, Tricyclic; Brain; Creatine Kinase; Depression; Dose-Response Relatio | 2009 |
The CYP2C19*17 genotype is associated with lower imipramine plasma concentrations in a large group of depressed patients.
Topics: Adult; Antidepressive Agents, Tricyclic; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2C19; De | 2010 |
Imipramine treatment increases the number of hippocampal synapses and neurons in a genetic animal model of depression.
Topics: Analysis of Variance; Animals; Antidepressive Agents; Cell Count; Depression; Disease Models, Animal | 2010 |
Antidepressant-like effects of cannabidiol in mice: possible involvement of 5-HT1A receptors.
Topics: Animals; Antidepressive Agents; Brain-Derived Neurotrophic Factor; Cannabidiol; Cannabis; Depression | 2010 |
Enhanced expression of BCL2/adenovirus EIB 19-kDa-interacting protein 3 mRNA, a candidate for intrinsic depression-related factor, and effects of imipramine in the frontal cortex of stressed mice.
Topics: Adaptation, Physiological; Animals; Antidepressive Agents, Tricyclic; Depression; Dose-Response Rela | 2010 |
Effects of serotonin (5-HT)2 receptor ligands on depression-like behavior during nicotine withdrawal.
Topics: Animals; Antidepressive Agents, Tricyclic; Depression; Imipramine; Male; Motor Activity; Neuropsycho | 2010 |
Transient early-life forebrain corticotropin-releasing hormone elevation causes long-lasting anxiogenic and despair-like changes in mice.
Topics: Adaptation, Ocular; Age Factors; Analysis of Variance; Animals; Animals, Newborn; Antidepressive Age | 2010 |
Clinical inquiries. What's best when a patient doesn't respond to the maximum dose of an antidepressant?
Topics: Antidepressive Agents; Antidepressive Agents, Second-Generation; Antipsychotic Agents; Bupropion; Co | 2010 |
Assessing the antidepressant-like effects of carbetocin, an oxytocin agonist, using a modification of the forced swimming test.
Topics: Animals; Antidepressive Agents; Brain; Depression; Imipramine; Immobilization; Injections, Intravent | 2010 |
Hippocampal astrocytes are necessary for antidepressant treatment of learned helplessness rats.
Topics: Animals; Antidepressive Agents, Tricyclic; Astrocytes; Citrates; Depression; Disease Models, Animal; | 2011 |
Alcohol-induced depressive-like behavior is associated with cortical norepinephrine reduction.
Topics: Animals; Depression; Ethanol; Female; Frontal Lobe; Hippocampus; Imipramine; Neurotransmitter Uptake | 2010 |
Effects of imipramine and lithium on the suppression of cell proliferation in the dentate gyrus of the hippocampus in adrenocorticotropic hormone-treated rats.
Topics: Adrenocorticotropic Hormone; Animals; Antidepressive Agents, Tricyclic; Antimanic Agents; Cell Proli | 2010 |
Exposure of mice to long-light: a new animal model to study depression.
Topics: Animals; Depression; Disease Models, Animal; Exploratory Behavior; Imipramine; Light; Male; Mice; Mi | 2010 |
Lithium addition to a tricyclic antidepressant results in optimal efficacy.
Topics: Antidepressive Agents; Antidepressive Agents, Tricyclic; Depression; Drug Resistance; Drug Synergism | 2011 |
Interaction between behavioral despair and addictive behaviors in rats.
Topics: Animals; Behavior, Addictive; Choice Behavior; Conditioning, Classical; Depression; Disease Models, | 2011 |
The antidepressant action of imipramine and venlafaxine involves suppression of nitric oxide synthesis.
Topics: Analysis of Variance; Animals; Antidepressive Agents; Behavior, Animal; Cyclohexanols; Depression; D | 2011 |
Ketamine plus imipramine treatment induces antidepressant-like behavior and increases CREB and BDNF protein levels and PKA and PKC phosphorylation in rat brain.
Topics: Animals; Antidepressive Agents; Brain; Brain-Derived Neurotrophic Factor; Cyclic AMP Response Elemen | 2011 |
Depressive-like behaviour of mice lacking cellular prion protein.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Depression; Disease Models, Animal; Exploratory Be | 2012 |
Do stress hormones connect environmental effects with behavior in the forced swim test?
Topics: Adaptation, Psychological; Adrenocorticotropic Hormone; Animals; Behavior, Animal; Body Temperature; | 2011 |
The novel δ opioid receptor agonist KNT-127 produces antidepressant-like and antinociceptive effects in mice without producing convulsions.
Topics: Analgesics; Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Behavior, Animal; Benz | 2011 |
Antidepressant-like effect induced by systemic and intra-hippocampal administration of DNA methylation inhibitors.
Topics: Animals; Antidepressive Agents; Azacitidine; Behavior, Animal; Brain-Derived Neurotrophic Factor; De | 2011 |
Chronic unpredictable stress-induced reduction in the hippocampal brain-derived neurotrophic factor (BDNF) gene expression is antagonized by zinc treatment.
Topics: Animals; Antidepressive Agents, Tricyclic; Brain-Derived Neurotrophic Factor; Depression; Disease Mo | 2011 |
Green odor and depressive-like state in rats: toward an evidence-based alternative medicine?
Topics: Administration, Inhalation; Animals; Antidepressive Agents, Tricyclic; Aromatherapy; Avoidance Learn | 2011 |
Pharmacological reversal of cognitive bias in the chick anxiety-depression model.
Topics: Analysis of Variance; Animals; Animals, Newborn; Antidepressive Agents; Anxiety; Bias; Chickens; Clo | 2012 |
Influence of Neuropeptide Y and antidepressants upon cerebral monoamines involved in depression: an in vivo electrochemical study.
Topics: Amygdala; Animals; Anti-Anxiety Agents; Antidepressive Agents; Antidepressive Agents, Tricyclic; Anx | 2011 |
Synthesis of 3,7-disubstituted imipramines by palladium-catalysed amination/cyclisation and evaluation of their inhibition of monoamine transporters.
Topics: Amination; Antidepressive Agents; Catalysis; Cyclization; Depression; Humans; Imipramine; Kinetics; | 2011 |
The antidepressant-like effects of glutamatergic drugs ketamine and AMPA receptor potentiator LY 451646 are preserved in bdnf⁺/⁻ heterozygous null mice.
Topics: Analysis of Variance; Animals; Antidepressive Agents; Brain-Derived Neurotrophic Factor; Depression; | 2012 |
Inhibition of iNOS induces antidepressant-like effects in mice: pharmacological and genetic evidence.
Topics: Animals; Antidepressive Agents; Brain; Depression; Disease Models, Animal; Dose-Response Relationshi | 2012 |
Increase in cortical pyramidal cell excitability accompanies depression-like behavior in mice: a transcranial magnetic stimulation study.
Topics: Action Potentials; Analysis of Variance; Animals; Antidepressive Agents, Tricyclic; Carrier Proteins | 2011 |
Antidepressants stimulate hippocampal neurogenesis by inhibiting p21 expression in the subgranular zone of the hipppocampus.
Topics: Animals; Antidepressive Agents; Blotting, Western; Cell Proliferation; Cyclin-Dependent Kinase Inhib | 2011 |
[Effect of antiasthenic drug ladasten on the level of cytokines and behavior in experimental model of anxious depression in C57BL/6 male mice].
Topics: Adamantane; Animals; Antidepressive Agents; Anxiety Disorders; Behavior, Animal; Depression; Disease | 2011 |
Antidepressants reduce extinction-induced withdrawal and biting behaviors: a model for depressive-like behavior.
Topics: Animals; Antidepressive Agents; Citalopram; Depression; Disease Models, Animal; Extinction, Psycholo | 2012 |
5-HT(1A) receptor and apoptosis contribute to interferon-α-induced "depressive-like" behavior in mice.
Topics: Animals; Antidepressive Agents; Apoptosis; Behavior, Animal; Depression; Hindlimb Suspension; Imipra | 2012 |
Testosterone and imipramine have antidepressant effects in socially isolated male but not female rats.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Castration; Depression; Drug Evaluation, Preclinic | 2012 |
MAGE-D1 regulates expression of depression-like behavior through serotonin transporter ubiquitylation.
Topics: Animals; Antidepressive Agents; Antigens, Neoplasm; Behavior, Animal; Brain; CHO Cells; Cricetinae; | 2012 |
Zinc deficiency induces behavioral alterations in the tail suspension test in mice. Effect of antidepressants.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Body Weight; Citalopram; Depression; Drug Resistan | 2012 |
Novel neurological and immunological targets for salicylate-based phytopharmaceuticals and for the anti-depressant imipramine.
Topics: Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Benzyl Alcohols; Brain; Cytokines; | 2012 |
Effect of ladasten on the content of cytokine markers of inflammation and behavior of mice with experimental depression-like syndrome.
Topics: Adamantane; Animals; Antidepressive Agents; Cytokines; Depression; Imipramine; Inflammation Mediator | 2011 |
Involvement of NMDA receptors in the antidepressant-like action of adenosine.
Topics: Adenosine; Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Chlorides; Depression; | 2012 |
N-acetylcysteine possesses antidepressant-like activity through reduction of oxidative stress: behavioral and biochemical analyses in rats.
Topics: Acetylcysteine; Animals; Antidepressive Agents; Antioxidants; Brain; Depression; Disease Models, Ani | 2012 |
Antidepressants prevent hierarchy destabilization induced by lipopolysaccharide administration in mice: a neurobiological approach to depression.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Cytokines; Depression; Disease Models, Animal; Flu | 2012 |
Amitifadine, a triple monoamine uptake inhibitor, reduces binge drinking and negative affect in an animal model of co-occurring alcoholism and depression symptomatology.
Topics: Affect; Alcoholism; Animals; Aza Compounds; Binge Drinking; Biogenic Monoamines; Bridged Bicyclo Com | 2012 |
The neuronal insulin sensitizer dicholine succinate reduces stress-induced depressive traits and memory deficit: possible role of insulin-like growth factor 2.
Topics: Animals; Antidepressive Agents; Anxiety; Depression; Disease Models, Animal; Hippocampus; Imipramine | 2012 |
A study on evalution of antidepressant effect of imipramine adjunct with Aswagandha and Bramhi.
Topics: Analysis of Variance; Animals; Antidepressive Agents; Depression; Disease Models, Animal; Helplessne | 2011 |
Indices of extinction-induced "depression" after operant learning using a runway vs. a cued free-reward delivery schedule.
Topics: Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Citalopram; Conditioning, Operant; Depr | 2012 |
Antidepressant-like effects of oxytocin in mice are dependent on the presence of insulin-regulated aminopeptidase.
Topics: Age Factors; Aminopeptidases; Angiotensin II; Animals; Antidepressive Agents; Cell Membrane; Cerebra | 2013 |
Sustained remission from depressive-like behavior depends on hippocampal neurogenesis.
Topics: Analysis of Variance; Animals; Antidepressive Agents; Astrocytes; Behavior, Animal; Cell Proliferati | 2013 |
Antidepressant effects of sleep deprivation require astrocyte-dependent adenosine mediated signaling.
Topics: Analysis of Variance; Animals; Astrocytes; Behavior, Animal; Depression; Hippocampus; Imipramine; Im | 2013 |
Enhanced cognitive function and antidepressant-like effects after krill oil supplementation in rats.
Topics: Animals; Antidepressive Agents; Avoidance Learning; Brain-Derived Neurotrophic Factor; Cognition; Cy | 2013 |
Antidepressant-like effects of essential oil and asarone, a major essential oil component from the rhizome of Acorus tatarinowii.
Topics: Acorus; Allylbenzene Derivatives; Animals; Anisoles; Antidepressive Agents; Depression; Disease Mode | 2013 |
Reduction of cGMP and nitric oxide has antidepressant-like effects in the forced swimming test in rats.
Topics: Animals; Antidepressive Agents, Tricyclic; Arginine; Cyclic GMP; Depression; Dimethyl Sulfoxide; Enz | 2002 |
Effect of imipramine hydrochloride on several models in subordinated mice.
Topics: Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Depression; Dominance-Subordination; Im | 2002 |
[Manic state during the addition of lithium in the case of depression resistant to imipramine].
Topics: Adult; Aged; Antidepressive Agents, Tricyclic; Bipolar Disorder; Depression; Drug Therapy, Combinati | 2002 |
Audioverbal cognitive dysfunction in depression. Factors involved.
Topics: Adolescent; Adult; Antidepressive Agents; Antidepressive Agents, Tricyclic; Attention; Cognition Dis | 2003 |
Cimicifuga extract BNO 1055: reduction of hot flushes and hints on antidepressant activity.
Topics: Animals; Behavior, Animal; Body Temperature; Cimicifuga; Depression; Dose-Response Relationship, Dru | 2003 |
Open space swimming test to index antidepressant activity.
Topics: Alanine; Animals; Antidepressive Agents; Behavior, Animal; Depression; Disease Models, Animal; Drug | 2003 |
Antidepressant-like effects in various mice strains in the tail suspension test.
Topics: Analysis of Variance; Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Behavior, An | 2003 |
Involvement of NMDA receptors and L-arginine-nitric oxide pathway in the antidepressant-like effects of zinc in mice.
Topics: Animals; Antidepressive Agents; Arginine; Ascorbic Acid; Behavior, Animal; Chlorides; Depression; Di | 2003 |
Depressive-like behavioral alterations and c-fos expression in the dopaminergic brain regions in WAG/Rij rats with genetic absence epilepsy.
Topics: Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Brain; Brain Chemistry; Choice Behavior | 2003 |
[Treatment of depressive states with special consideration of tofranil, a new antidepressant].
Topics: Antidepressive Agents; Depression; Depressive Disorder; Imipramine; Tranquilizing Agents | 1958 |
The treatment of depressive states with G 22355 (imipramine hydrochloride).
Topics: Depression; Depressive Disorder; Imipramine; Tranquilizing Agents | 1958 |
The treatment of depressive conditions with imipramine (G 22355).
Topics: Depression; Depressive Disorder; Imipramine; Tranquilizing Agents | 1958 |
[Treatment of states of depression with tofranil].
Topics: Acridines; Depression; Depressive Disorder; Imipramine | 1958 |
[Findings on the special psychological effect of the thymoleptic tofranil].
Topics: Acridines; Antidepressive Agents; Depression; Depressive Disorder; Imipramine; Mental Disorders | 1958 |
[Trial therapy of depressive states with G. 22355: tofranil].
Topics: Depression; Depressive Disorder; Imipramine; Tranquilizing Agents | 1959 |
Imipramine (tofranil); a new drug for the depressed.
Topics: Depression; Depressive Disorder; Imipramine; Tranquilizing Agents | 1959 |
The use of imipramine (tofranil) for depressive states in open ward settings of a general hospital: a preliminary report.
Topics: Depression; Depressive Disorder; Hospitals; Hospitals, General; Imipramine; Tranquilizing Agents | 1959 |
Imipramine (tofranil): a safe, effective antidepressant drug in private practice.
Topics: Antidepressive Agents; Depression; Depressive Disorder; Imipramine; Private Practice; Tranquilizing | 1959 |
Clinical experience with imipramine (G22355) in the treatment of depression.
Topics: Depression; Depressive Disorder; Imipramine; Tranquilizing Agents | 1959 |
[Treatment of depressive conditions in psychiatric practice with tofranil].
Topics: Depression; Depressive Disorder; Imipramine; Tranquilizing Agents | 1959 |
Effects of imipramine (tofranil) on depressive states; a clinical and psychodynamic study.
Topics: Depression; Depressive Disorder; Imipramine; Tranquilizing Agents | 1959 |
[Study of the effectiveness of imipramine in the treatment of depressive states].
Topics: Depression; Depressive Disorder; Imipramine; Tranquilizing Agents | 1959 |
Tofranil, a new anti-depressant.
Topics: Acridines; Depression; Depressive Disorder; Imipramine | 1959 |
[Results of ambulatory treatment of psychic depression with an iminodibenzyl derivative (tofranil Geigy)].
Topics: Benzylamines; Depression; Depressive Disorder; Imipramine; Tranquilizing Agents | 1959 |
[Medicinal treatment of depressive syndromes with tofranil].
Topics: Depression; Depressive Disorder; Imipramine; Tranquilizing Agents | 1959 |
[Provisional statistics on the therapeutic results obtained with the use of G22355 (tofranil) in 80 depressive states].
Topics: Acridines; Biometry; Depression; Depressive Disorder; Imipramine | 1959 |
[New chemotherapeutic drugs for depressive & melancholic states; imipramine].
Topics: Depression; Depressive Disorder; Imipramine; Tranquilizing Agents | 1959 |
[Treatment of depressive states with the iminodibenzyl derivative G-22355 (tofranil); preliminary note].
Topics: Benzylamines; Depression; Depressive Disorder; Imipramine; Tranquilizing Agents | 1959 |
[An iminodibenzyl derivative (tofranil) in the treatment of depressive states].
Topics: Benzylamines; Depression; Depressive Disorder; Imipramine; Tranquilizing Agents | 1959 |
[Our experience on treatment with tofranil].
Topics: Depression; Depressive Disorder; Imipramine; Tranquilizing Agents | 1959 |
[Tofranil in the treatment of depression].
Topics: Depression; Depressive Disorder; Imipramine; Tranquilizing Agents | 1959 |
Management of the depressed patient; preliminary observations concerning the use of imipramine hydrochloride.
Topics: Depression; Depressive Disorder; Disease Management; Imipramine; Tranquilizing Agents | 1959 |
Depressive states and drugs; a study of the use of imipramine tofranil in open psychiatric settings.
Topics: Depression; Imipramine; Tranquilizing Agents | 1959 |
Office treatment of depressive states with a new drug (imipramine).
Topics: Depression; Depressive Disorder; Imipramine; Tranquilizing Agents | 1959 |
[Clinical & ambulant treatment of depressive states with tofranil (G. 22355)].
Topics: Depression; Depressive Disorder; Imipramine; Tranquilizing Agents | 1959 |
[Treatment of endogenous depressions with tofranil].
Topics: Depression; Depressive Disorder; Imipramine; Tranquilizing Agents | 1959 |
[Pharmacotherapy of depressive states with the iminodibenzyl derivative tofranil].
Topics: Benzylamines; Depression; Depressive Disorder; Imipramine; Tranquilizing Agents | 1959 |
A clinical evaluation of four antidepressant drugs (nardil, tofranil, marplan, and deprol).
Topics: Antidepressive Agents; Depression; Depressive Disorder; Hydrazines; Imipramine; Parasympatholytics; | 1961 |
[Experiences with tofranil in the therapy of depressive states. A functional-dynamic theory on the pathogenesis of depressive states and the mechanism of action of tofranil].
Topics: Depression; Imipramine; Psychopharmacology | 1960 |
[On the treatment of depressive states with the iminodibenzyl derivative Tofranil].
Topics: Benzylamines; Depression; Depressive Disorder; Imipramine; Psychopharmacology | 1961 |
A clinical trial of imipramine ("Tofranil") on depressed patients.
Topics: Depression; Depressive Disorder; Imipramine; Psychopharmacology | 1961 |
Imipramine in chronic depression.
Topics: Depression; Depressive Disorder; Imipramine; Psychopharmacology | 1960 |
[Imipramine and alimemazine. Application of the law of stages].
Topics: Depression; Depressive Disorder; Imipramine; Psychopharmacology; Trimeprazine | 1960 |
[Clinical experiences with Tofranil in the treatment of depression].
Topics: Depression; Depressive Disorder; Imipramine | 1961 |
[Medicopsychological research on the effects of Tofranil on normal and sick persons].
Topics: Depression; Depressive Disorder; Imipramine; Psychopharmacology; Research | 1961 |
[Side effects and hazards of imipramine therapy].
Topics: Depression; Depressive Disorder; Imipramine; Psychopharmacology | 1961 |
[Clinical and experimental trials of imipramine (tofranil)].
Topics: Depression; Depressive Disorder; Imipramine; Psychopharmacology | 1960 |
[Treatment with imizin (tofranil) of depressive conditions].
Topics: Bipolar Disorder; Depression; Depressive Disorder; Humans; Imipramine; Mental Disorders; Psychopharm | 1961 |
[Danger of treatment with tofranil in ambulatory care].
Topics: Ambulatory Care; Depression; Depressive Disorder; Humans; Imipramine; Psychopharmacology | 1960 |
[Treatment of depressive states in old age with imipramine].
Topics: Aged; Aged, 80 and over; Depression; Depressive Disorder; Imipramine; Psychopharmacology | 1961 |
Trial of imipramine.
Topics: Depression; Depressive Disorder; Imipramine; Psychopharmacology | 1960 |
Imipramine in office management of depressive reactions. (A double blind clinical study).
Topics: Adjustment Disorders; Depression; Depressive Disorder; Double-Blind Method; Imipramine; Office Manag | 1961 |
[2 years of experience with imipramine].
Topics: Depression; Depressive Disorder; Humans; Imipramine; Neurotic Disorders; Obsessive-Compulsive Disord | 1961 |
[Significance of imipramine in the medico-psychopedagogical reduction of depressive behavior in the form of anxiety and inhibition].
Topics: Anxiety; Anxiety Disorders; Depression; Depressive Disorder; Imipramine; Psychopharmacology | 1961 |
Imipramine (tofranil) in mental health clinic and private practice.
Topics: Depression; Depressive Disorder; Imipramine; Mental Health; Private Practice; Psychopharmacology | 1960 |
[Imipramine chloride in depressive syndromes].
Topics: Bipolar Disorder; Chlorides; Depression; Depressive Disorder; Humans; Imipramine; Mental Disorders; | 1961 |
Tofranil in the treatment of depressive states. A clinical evaluation of 120 out-patients.
Topics: Depression; Depressive Disorder; Imipramine; Outpatients; Psychopharmacology | 1960 |
Comparison of marplan and tofranil in the treatment of depressive states.
Topics: Depression; Depressive Disorder; Hydrazines; Imipramine; Psychopharmacology | 1961 |
Preliminary observations on the use of imipramine in the treatment of depression.
Topics: Depression; Depressive Disorder; Imipramine; Psychopharmacology | 1960 |
[Combined sleep and "Tofranil" therapy: treatment of anxious depressions].
Topics: Depression; Depressive Disorder; Imipramine; Psychopharmacology; Sleep | 1961 |
A controlled trial of imipramine ("Tofranil") in the treatment of severe depressive states.
Topics: Depression; Depressive Disorder; Imipramine; Psychopharmacology | 1961 |
[A short survey of some cases of mild depression treated with tofranil on an ambulatory basis].
Topics: Data Collection; Depression; Depressive Disorder; Imipramine; Psychopharmacology | 1960 |
[Contributions on the therapy of exogenous states of depression with Tofranil "Geigy"].
Topics: Depression; Depressive Disorder; Imipramine; Psychopharmacology | 1961 |
[A case of depression cured by imipramine. Critical study].
Topics: Depression; Depressive Disorder; Imipramine; Psychopharmacology | 1960 |
Imipramine treatment.
Topics: Depression; Depressive Disorder; Imipramine; Psychopharmacology | 1960 |
Cardiac complications during treatment with imipramin (Tofranil).
Topics: Depression; Depressive Disorder; Electrocardiography; Heart Diseases; Humans; Imipramine; Psychophar | 1961 |
Depression treated with imipramine: a follow-up study.
Topics: Depression; Depressive Disorder; Follow-Up Studies; Imipramine | 1961 |
Combined pharmaco-fever treatment with imipramine (tofranil) and typhoid vaccine in the management of depressive conditions.
Topics: Combined Modality Therapy; Depression; Depressive Disorder; Fever; Hyperthermia, Induced; Imipramine | 1960 |
[Studies on bio-electrical activity changes in the cortex of the greater hemispheres in patients with depressive states during the treatment with imizin (tofranil)].
Topics: Bipolar Disorder; Depression; Depressive Disorder; Electroencephalography; Humans; Imipramine; Menta | 1961 |
Parkinson's syndrome, depression and imipramine. A preliminary report.
Topics: Depression; Depressive Disorder; Humans; Imipramine; Irritable Mood; Motivation; Muscle Rigidity; Pa | 1961 |
[Electroclinical aspects of a case of acute voluntary poisoning with imipramine].
Topics: Depression; Depressive Disorder; Imipramine; Psychopharmacology; Suicide | 1961 |
[Concept of depression; treatment of depressive states with Tofranil].
Topics: Depression; Depressive Disorder; Imipramine; Psychopharmacology | 1961 |
[Treatment of depression with imizin (tofranil)].
Topics: Bipolar Disorder; Depression; Depressive Disorder; Humans; Imipramine; Mental Disorders; Psychopharm | 1961 |
[Tofranil in the treatment of depressive states during radiotherapy].
Topics: Depression; Depressive Disorder; Imipramine; Psychopharmacology; Radiation Injuries; Radiotherapy | 1960 |
[Tofranil in the therapy of depressions].
Topics: Depression; Imipramine; Psychopharmacology | 1960 |
Effect of imipramine (Tofranil) on depression and hyperkinesia in Huntington's disease.
Topics: Chorea; Depression; Depressive Disorder; Humans; Huntington Disease; Hyperkinesis; Imipramine; Movem | 1961 |
[Therapy of depressive states with tofranil (G-22355 Geigy)].
Topics: Depression; Depressive Disorder; Imipramine; Tranquilizing Agents | 1959 |
Tofranil-treatment of endogenous depressions.
Topics: Depression; Depressive Disorder; Humans; Imipramine; Tranquilizing Agents | 1959 |
[Combined electroshock-tofranil therapy of melancholia].
Topics: Depression; Depressive Disorder; Electroconvulsive Therapy; Electroshock; Imipramine; Psychopharmaco | 1960 |
[Case contribution on ambulant treatment with tofranil)].
Topics: Depression; Depressive Disorder; Imipramine; Tranquilizing Agents | 1959 |
A controlled trial of imipramine in treatment of depressive states.
Topics: Depression; Depressive Disorder; Imipramine; Tranquilizing Agents | 1959 |
[Controversial questions in the treatment of depressive states by tofranil].
Topics: Depression; Depressive Disorder; Imipramine; Psychopharmacology | 1960 |
Alteration of the clinical picture during tofranil therapy.
Topics: Depression; Depressive Disorder; Imipramine; Tranquilizing Agents | 1959 |
[The treatment of depression with tofranil].
Topics: Depression; Depressive Disorder; Imipramine; Tranquilizing Agents | 1959 |
The use of tofranil in the aged.
Topics: Aged; Aged, 80 and over; Depression; Depressive Disorder; Geriatrics; Imipramine; Tranquilizing Agen | 1959 |
[Imipramine hydrochloride in the treatment of depressive states].
Topics: Depression; Depressive Disorder; Imipramine; Psychopharmacology | 1960 |
The use of tofranil (imipramine) for depressive states in private psychiatric out-patient practice: a preliminary evaluation.
Topics: Depression; Depressive Disorder; Imipramine; Outpatients; Patients; Private Practice; Tranquilizing | 1959 |
Home treatment of depression with imipramine (tofranil).
Topics: Depression; Depressive Disorder; Imipramine; Psychopharmacology | 1960 |
[Contribution to the study of the treatment of depressive states with G 22355 (tofranil)].
Topics: Depression; Depressive Disorder; Imipramine; Psychopharmacology | 1959 |
[The treatment of depressions in a non-hospital environment with G.22355 (tofranil)].
Topics: Depression; Depressive Disorder; Imipramine; Psychopharmacology | 1960 |
[On pharmacotherapy of depressive syndromes with the iminodibenzyl derivative, tofranil].
Topics: Benzylamines; Depression; Depressive Disorder; Humans; Imipramine; Psychopharmacology | 1960 |
Efficacy of tofranil in the treatment of various types of depression: a comparison with other antidepressant drugs.
Topics: Antidepressive Agents; Depression; Depressive Disorder; Imipramine; Tranquilizing Agents | 1959 |
[Trial imipramine therapy of refractory depressive states].
Topics: Depression; Depressive Disorder; Imipramine; Psychopharmacology | 1959 |
[Imipramine treatment in other than depressive states].
Topics: Depression; Humans; Imipramine; Neurotic Disorders; Obsessive-Compulsive Disorder; Psychopharmacolog | 1960 |
Myocardial infarction during imipramine treatment of depression.
Topics: Cardiovascular Diseases; Depression; Depressive Disorder; Humans; Imipramine; Myocardial Infarction; | 1960 |
"Tofranil"--a new anti-depressant drug.
Topics: Depression; Depressive Disorder; Imipramine; Psychopharmacology | 1960 |
[Treatment of depressive states. Clinical experiences with tofranil].
Topics: Depression; Depressive Disorder; Imipramine; Psychopharmacology | 1960 |
[Electroencephalographic data in patients with depressive dysthymia treated with tofranil (iminodibenzyl derivative G 22355)].
Topics: Benzylamines; Depression; Depressive Disorder; Electroencephalography; Imipramine; Tranquilizing Age | 1959 |
[Experiences with tofranil (G 22355) in the treatment of depressive states].
Topics: Depression; Depressive Disorder; Imipramine; Tranquilizing Agents | 1959 |
Controlled assessment of antidepressant drugs, including tofranil.
Topics: Antidepressive Agents; Depression; Depressive Disorder; Humans; Imipramine | 1959 |
Imipramine therapy of depressive syndromes.
Topics: Depression; Depressive Disorder; Imipramine | 1960 |
[Ozena and nervous depression improved by imipramine].
Topics: Anxiety; Atrophy; Depression; Depressive Disorder; Humans; Imipramine; Psychopharmacology; Rhinitis; | 1960 |
[Trial imipramine therapy of refractory depressive states].
Topics: Depression; Depressive Disorder; Imipramine | 1959 |
The methacholine test in endogenous depression treated with imipramine (tofranil).
Topics: Autonomic Nervous System; Depression; Depressive Disorder; Imipramine; Methacholine Chloride; Nervou | 1961 |
A clinical analysis of the effects of tofranil in depression. Longitudinal and follow-up studies. Treatment of blood-relations.
Topics: Antidepressive Agents; Depression; Depressive Disorder; Family; Follow-Up Studies; Humans; Imipramin | 1961 |
Treatment of recurrent mental depression with imipramine.
Topics: Chronic Disease; Depression; Depressive Disorder; Depressive Disorder, Major; Imipramine | 1961 |
Clinical trial with desmethylimipramine (G-35020), a new antidepressive compound.
Topics: Antidepressive Agents; Depression; Depressive Disorder; Desipramine; Imipramine | 1962 |
[Electroencephalographic data in patients affected by a depressive syndrome treated with trimeproprimine (FI-6120, RP-7162: Surmontyl)].
Topics: Depression; Depressive Disorder; Electroencephalography; Imipramine | 1962 |
A preliminary clinical survey on imipramine.
Topics: Depression; Depressive Disorder; Humans; Imipramine | 1962 |
[Treatment with Tofranil of depressive states].
Topics: Depression; Imipramine | 1962 |
[Our experiences with ambulatory Tofranil therapy].
Topics: Depression; Depressive Disorder; Imipramine | 1962 |
[Experience in treatment with Tofranil of patients with depressive states].
Topics: Depression; Imipramine | 1962 |
Clinical features of depression and the response to imipramine ("Tofranil").
Topics: Depression; Depressive Disorder; Imipramine | 1962 |
Imipramine (Tofranil) in depressive states: a controlled trial with inpatients.
Topics: Depression; Depressive Disorder; Imipramine; Inpatients; Psychopharmacology | 1961 |
[Experience with Tofranil in psychiatric office practice].
Topics: Depression; Depressive Disorder; Imipramine | 1962 |
[Preliminary contribution to the application of a psychopharmacological method of differential diagnostic evaluation of depression].
Topics: Amphetamine; Amphetamines; Central Nervous System; Depression; Depressive Disorder; Diagnosis, Diffe | 1961 |
A doubleblind comparison of placebo and imipramine in the treatment of depressed patients in a state hospital.
Topics: Depression; Depressive Disorder; Double-Blind Method; Hospitals, State; Imipramine | 1961 |
Effects and interactions of imipramine, chlorpromazine, reserpine and amphetamine on self-stimulation: possible neurophysiological basis of depression.
Topics: Amphetamine; Amphetamines; Chlorpromazine; Depression; Depressive Disorder; Imipramine; Reserpine; S | 1961 |
[Tofranil treatment of dysphoria in criminals].
Topics: Criminal Psychology; Criminals; Depression; Depressive Disorder; Depressive Disorder, Major; Imipram | 1961 |
[Clinical and electroencephalographic correlates in the course of treatment of 14 melancholia syndromes with imipramine].
Topics: Depression; Depressive Disorder; Electroencephalography; Humans; Imipramine; Syndrome | 1963 |
[Experience with imipramine].
Topics: Depression; Depressive Disorder; Humans; Imipramine; Mental Disorders | 1963 |
Differentiation of two genetically specific types of depression by the response to anti-depressants.
Topics: Antidepressive Agents; Depression; Depressive Disorder; Imipramine; Iproniazid; Isocarboxazid; Monoa | 1962 |
Imipramine-N-oxide: preliminary investigation of a new antidepressive drug.
Topics: Antidepressive Agents; Depression; Depressive Disorder; Humans; Imipramine | 1963 |
[Decisive change in the neurological treatment of depression].
Topics: Depression; Depressive Disorder; Humans; Imipramine | 1962 |
Treatment of depression: a comparative study of E.C.T. and six drugs.
Topics: Antidepressive Agents; Chlorprothixene; Depression; Depressive Disorder; Electroconvulsive Therapy; | 1963 |
[Depressive state in oligophrenia treated with Tofranil].
Topics: Depression; Depressive Disorder; Imipramine; Intellectual Disability | 1962 |
A trial of imipramine (Tofranil) in depressed patients with chronic physical disease.
Topics: Chronic Disease; Depression; Depressive Disorder; Imipramine; Physical Examination | 1963 |
One year follow-up of depressed patients treated in a multi-hospital drug study. I. Social workers' evaluations.
Topics: Amobarbital; Depression; Depressive Disorder; Dextroamphetamine; Drug Evaluation; Follow-Up Studies; | 1962 |
Plasma imipramine level in syndromes of depression.
Topics: Aged; Bipolar Disorder; Depression; Depressive Disorder; Humans; Imipramine; Mental Disorders; Psych | 1962 |
Non-fatal reaction to imipramine-MAO inhibitor combination.
Topics: Depression; Depressive Disorder; Humans; Imipramine; Monoamine Oxidase Inhibitors | 1963 |
[Remarks on the correlative use of imipramine and institutional therapy].
Topics: Depression; Depressive Disorder; Imipramine; Psychotherapy; Schizophrenia | 1963 |
Effects of G-33040 (ensidon) and G-35020 (petrofrane) and depressive states. A comparative multi-blind study.
Topics: Antidepressive Agents; Depression; Humans; Imipramine | 1962 |
[Autonomic research, therapy and prognosis of exhaustion depressions].
Topics: Autonomic Nervous System; Chlorprothixene; Depression; Depressive Disorder; Fatigue; Humans; Imipram | 1962 |
Imipramine in depression: a controlled study.
Topics: Depression; Depressive Disorder; Humans; Imipramine; Research Design | 1962 |
[Imizin treatment of depressive states in oncological patients in the process of roentgen therapy].
Topics: Depression; Humans; Imipramine; Radiotherapy | 1963 |
Imipramine with electrical treatment in depression--a controlled trial.
Topics: Convulsive Therapy; Depression; Depressive Disorder; Electricity; Electroconvulsive Therapy; Humans; | 1962 |
[Tofranil in ambulatory treatment in depressive states].
Topics: Depression; Depressive Disorder; Imipramine | 1962 |
[Imipramine].
Topics: Brain Injuries; Depression; Depressive Disorder; Humans; Imipramine | 1962 |
Antidepressants: comparison of clinical effects in anergic schizophrenia and the depressed states.
Topics: Antidepressive Agents; Depression; Imipramine; Iproniazid; Isocarboxazid; Monoamine Oxidase Inhibito | 1963 |
The treatment of depression in hospitalized patients before and since the introduction of antidepressant drugs.
Topics: Antidepressive Agents; Depression; Electroconvulsive Therapy; Humans; Imipramine; Monoamine Oxidase | 1962 |
[Removal depressions].
Topics: Aged; Depression; Depressive Disorder; Humans; Imipramine | 1963 |
Treatment of facial and head pain associated with depression.
Topics: Depression; Depressive Disorder; Face; Headache; Hydrazines; Imipramine; Neuralgia | 1962 |
A comparison of imipramine, electroconvulsive therapy and placebo in the treatment of depressions.
Topics: Depression; Depressive Disorder; Electroconvulsive Therapy; Humans; Imipramine; Placebos | 1962 |
[Some aspects of the treatment of depressive conditions with tofranil and nozinan].
Topics: Depression; Depressive Disorder; Imipramine; Methotrimeprazine | 1961 |
[Effect of Imipramine on serum potassium, calcium and phosphorus in depressive conditions].
Topics: Calcium; Calcium, Dietary; Depression; Depressive Disorder; Hematologic Tests; Humans; Imipramine; P | 1962 |
A controlled clinical trial of imipramine (Tofranil) with out-patients.
Topics: Depression; Depressive Disorder; Humans; Imipramine; Outpatients | 1963 |
[Tofranil therapy of depression].
Topics: Depression; Depressive Disorder; Humans; Imipramine | 1962 |
Fluid distribution and the response of depression to E.C.T. and imipramine.
Topics: Body Fluids; Depression; Depressive Disorder; Electroconvulsive Therapy; Humans; Imipramine | 1963 |
[Rheographic study of patients with depression treated with imipramine].
Topics: Bipolar Disorder; Depression; Depressive Disorder; Humans; Imipramine; Mental Disorders; Psychotic D | 1962 |
[Endogenous depression and its treatment].
Topics: Antidepressive Agents; Depression; Depressive Disorder; Electroconvulsive Therapy; Humans; Imipramin | 1963 |
[On the effect of imipramine in depression].
Topics: Depression; Depressive Disorder; Humans; Imipramine | 1962 |
[Combined Tofranil-Pyrifer therapy of endogenous depression].
Topics: Depression; Depressive Disorder; Imipramine; Lipopolysaccharides; Psychotherapy, Multiple | 1962 |
The combined treatment of endogenous depression with imipramine (tofranil) and chlorprothixene (truxal), with special reference to ambulant therapy.
Topics: Chlorprothixene; Combined Modality Therapy; Depression; Depressive Disorder; Exercise Therapy; Human | 1961 |
[TOFRANIL TREATMENT AND DEPRESSION IN CHILDREN AND ADOLESCENTS].
Topics: Adolescent; Child; Depression; Depressive Disorder; Humans; Imipramine | 1963 |
PSYCHOPHARMACOLOGY OF IMIPRAMINE.
Topics: Depression; Depressive Disorder; Humans; Imipramine; Psychopharmacology; Toxicology | 1963 |
A CONTROLLED COMPARISON OF ELECTROCONVULSIVE THERAPY, IMIPRAMINE AND THIOPENTONE SLEEP IN DEPRESSION.
Topics: Convulsive Therapy; Depression; Depressive Disorder; Electricity; Electroconvulsive Therapy; Humans; | 1963 |
THE USE OF "PERTOFRAN" IN DEPRESSION: A SHORT COMMUNICATION.
Topics: Communication; Depression; Depressive Disorder; Desipramine; Humans; Imipramine | 1963 |
COMBINED ADMINISTRATION OF DESIPRAMINE AND RESERPINE OR TETRABENAZINE IN DEPRESSIVE PATIENTS.
Topics: Antidepressive Agents; Depression; Depressive Disorder; Desipramine; Humans; Imipramine; Reserpine; | 1963 |
COMPARISON BETWEEN IMIPRAMINE AND DESIPRAMINE IN NORMAL SUBJECTS AND THEIR ACTION IN DEPRESSIVE PATIENTS.
Topics: Antidepressive Agents; Depression; Depressive Disorder; Desipramine; Humans; Imipramine | 1963 |
MULTIPLE ITEM FACTORS AS CHANGE MEASURES IN PSYCHOPHARMACOLOGY.
Topics: Chlorpromazine; Depression; Depressive Disorder; Factor Analysis, Statistical; Humans; Imipramine; P | 1963 |
TREATMENT OF SEVERE DEPRESSION WITH DESIPRAMINE, A METABOLITE OF IMIPRAMINE.
Topics: Adolescent; Antidepressive Agents; Brain Diseases; Depression; Depressive Disorder; Depressive Disor | 1963 |
ANTI-DEPRESSANT DRUGS.
Topics: Amitriptyline; Antidepressive Agents; Depression; Depressive Disorder; Geriatrics; Headache; Imipram | 1963 |
PARGYLINE IN THE TREATMENT OF DEPRESSIVE ILLNESSES.
Topics: Antidepressive Agents; Antihypertensive Agents; Depression; Depressive Disorder; Hypotension; Imipra | 1963 |
A CONTROLLED STUDY OF TREATMENTS OF DEPRESSION.
Topics: Convulsive Therapy; Depression; Depressive Disorder; Electroconvulsive Therapy; Humans; Imipramine; | 1963 |
[DATA FOR THE NEUROPHYSIOLOGICAL ANALYSIS OF THE ANTIDEPRESSIVE ACTION OF TOFRANIL].
Topics: Adrenocorticotropic Hormone; Antidepressive Agents; Conditioning, Classical; Depression; Depressive | 1963 |
[CRITICAL CONSIDERATIONS ON THE PHARMACOTHERAPY OF DEPRESSION].
Topics: Amitriptyline; Antidepressive Agents; Depression; Depressive Disorder; Hydrazines; Imipramine; Ipron | 1963 |
NORMOTHYMOTICS, "MOOD-NORMALIZERS": ARE LITHIUM AND THE IMIPRAMINE DRUGS SPECIFIC FOR AFFECTIVE DISORDERS?
Topics: Antipsychotic Agents; Bipolar Disorder; Depression; Depressive Disorder; Electrocardiography; Emotio | 1963 |
PRELIMINARY CLINICAL EXPERIENCES WITH AN IMIPRAMINE-METABOLITE, G 35020, DESMETHYL-IMIPRAMINE-DMI.
Topics: Blood Pressure; Depression; Depressive Disorder; Electrocardiography; Electroencephalography; Geriat | 1963 |
DIAGNOSIS AND MANAGEMENT OF DEPRESSION.
Topics: Central Nervous System Stimulants; Depression; Depressive Disorder; Diagnosis; Electroconvulsive The | 1963 |
CLINICAL JUDGMENT IN PSYCHOPHARMACOLOGICAL RESEARCH.
Topics: Depression; Depressive Disorder; Humans; Imipramine; Judgment; Placebos; Psychopharmacology; Researc | 1963 |
THE USE OF AN ANTIDEPRESSANT DRUG IN CHRONICALLY ALLERGIC INDIVIDUALS; A DOUBLE BLIND STUDY.
Topics: Antidepressive Agents; Asthma; Atropine; Depression; Dermatitis; Dermatitis, Contact; Double-Blind M | 1963 |
[STUDY OF CEREBRAL HEMODYNAMICS IN THE DEPRESSIVE STATES].
Topics: Amitriptyline; Bipolar Disorder; Cerebrovascular Circulation; Depression; Depressive Disorder; Depre | 1963 |
[OUR CLINICAL EXPERIENCE WITH AMITRIPTYLINE].
Topics: Adolescent; Amitriptyline; Bipolar Disorder; Depression; Depressive Disorder; Depressive Disorder, M | 1963 |
[THE ANTIDEPRESSANTS. DRUG INCOMPATIBILITY].
Topics: Antidepressive Agents; Chlordiazepoxide; Chlorpromazine; Depression; Drug Incompatibility; Imipramin | 1963 |
[ON IMIPRAMINE THERAPY IN PSYCHIC INSUFFICIENCY STATES].
Topics: Biometry; Depression; Depressive Disorder; Humans; Imipramine; Statistics as Topic | 1963 |
IMIPRAMINE AND "DRINAMYL" IN DEPRESSIVE ILLNESS: A COMPARATIVE TRIAL.
Topics: Amobarbital; Antidepressive Agents; Depression; Depressive Disorder; Dextroamphetamine; Imipramine; | 1964 |
[THE PSYCHOPHYSIOLOGICAL EFFECTS OF METHYLDOPA].
Topics: Blood Pressure; Blood Pressure Determination; Depression; Depressive Disorder; Dihydroxyphenylalanin | 1963 |
A COMPARISON OF SUBJECTIVE RESPONSES TO IMIPRAMINE AND TRANYLCYPROMINE.
Topics: Aged; Depression; Depressive Disorder; Humans; Imipramine; Tranylcypromine | 1964 |
EFFECTS OF CHLORPROMAZINE AND IMIPRAMINE ON SYSTOLIC BLOOD PRESSURE IN PSYCHIATRIC PATIENTS: RELATIONSHIPS TO AGE, DIAGNOSIS AND INITIAL BLOOD PRESSURE.
Topics: Blood Pressure; Chlorpromazine; Depression; Depressive Disorder; Humans; Imipramine; Mental Disorder | 1964 |
EFFECTS OF IMIPRAMINE UPON VARIOUS MENTAL SYNDROMES IN AMBULATORY TREATMENT.
Topics: Anxiety; Anxiety Disorders; Autonomic Nervous System Diseases; Dementia; Depression; Humans; Imipram | 1963 |
[MANIA-LIKE SYNDROME AFTER TOFRANIL].
Topics: Antisocial Personality Disorder; Bipolar Disorder; Depression; Depressive Disorder, Major; Imipramin | 1963 |
[DESMETHYLIMIPRAMINE (PERTOFRAN) IN THE TREATMENT OF DEPRESSIONS. A CLINICAL AND PSYCHODYNAMIC APPRAISAL].
Topics: Antidepressive Agents; Biomedical Research; Bipolar Disorder; Chlorpromazine; Depression; Depressive | 1963 |
[PRELIMINARY OBSERVATIONS ON THE CLINICAL USE OF A METABOLITE OF IMIPRAMINE: DESMETHYLIMIPRAMINE (G 35020)].
Topics: Antidepressive Agents; Depression; Depressive Disorder; Desipramine; Humans; Imipramine; Mental Diso | 1963 |
METHOTRIMEPRAZINE AS AN ADJUNCT TO IMIPRAMINE IN DEPRESSION.
Topics: Biomedical Research; Depression; Depressive Disorder; Imipramine; Mental Disorders; Methotrimeprazin | 1963 |
[THE ASSOCIATION EXPERIMENT BY JUNG AS A THERAPEUTIC AND DIAGNOSTIC AID AND CATAMNESTIC CONTROL INSTRUMENT. (DEMONSTRATED BY THE PSYCHOTHERAPY OF "TIMID HANS")].
Topics: Depression; Depressive Disorder; Humans; Imipramine; Psychoanalytic Interpretation; Psychotherapy; S | 1964 |
DEPRESSIONS... THEIR MANAGEMENT AND TREATMENT.
Topics: Amitriptyline; Amobarbital; Bipolar Disorder; Depression; Depressive Disorder; Electroconvulsive The | 1964 |
DIFFERENT POPULATIONS, DIFFERENT DRUG RESPONSES. A COMPARATIVE STUDY OF TWO ANTI-DEPRESSANTS, EACH USED IN TWO DIFFERENT PATIENT GROUPS.
Topics: Antidepressive Agents; Benactyzine; Depression; Humans; Imipramine; Meprobamate; Pharmacology; Place | 1964 |
EVALUATION OF THE ANTIDEPRESSANT ACTION OF MELIPRAMINE.
Topics: Antidepressive Agents; Anxiety; Brain; Cats; Depression; Electrophysiology; Hypochondriasis; Imipram | 1963 |
DIFFERENTIAL RESPONSE OF HOSPITALIZED DEPRESSED PATIENTS TO SOMATIC THERAPY.
Topics: Bipolar Disorder; Depression; Depressive Disorder; Depressive Disorder, Major; Electroconvulsive The | 1964 |
THE PHARMACOLOGY AND BIOCHEMISTRY OF DEPRESSION.
Topics: Amitriptyline; Antidepressive Agents; Biochemical Phenomena; Biochemistry; Brain; Depression; Depres | 1964 |
DEPRESSION MASQUERADING AS APATHY.
Topics: Amitriptyline; Apathy; Depression; Depressive Disorder; Electronarcosis; Humans; Imipramine; Perphen | 1964 |
A CONTROLLED TRIAL OF IMIPRAMINE.
Topics: Biomedical Research; Depression; Depressive Disorder; Humans; Imipramine; Placebos | 1964 |
SPEECH DISTURBANCE ASSOCIATED WITH THE USE OF IMIPRAMINE.
Topics: Depression; Imipramine; North Carolina; Pharmacology; Speech; Speech Disorders; Toxicology | 1964 |
[IMIPRAMINE POISONING].
Topics: Adolescent; Antidepressive Agents; Coma; Depression; Depressive Disorder; Geriatrics; Imipramine; Mu | 1964 |
THE USE OF DRUGS IN PSYCHOTHERAPY.
Topics: Antidepressive Agents; Barbiturates; Central Nervous System; Depression; Electroconvulsive Therapy; | 1964 |
DEPRESSIVE AND MANIC PSYCHOSES AND ALLIED DISORDERS.
Topics: Adolescent; Amitriptyline; Antidepressive Agents; Barbiturates; Bipolar Disorder; Depression; Electr | 1964 |
[RESULTS WITH PSYCHOTROPIC DRUGS IN OUTPATIENT TREATMENT].
Topics: Chlorpromazine; Depression; Depressive Disorder; Female; Humans; Imipramine; Iproniazid; Mental Diso | 1964 |
CALCIUM METABOLISM IN STATES OF DEPRESSION.
Topics: Calcium; Depression; Depressive Disorder; Electroconvulsive Therapy; Humans; Imipramine; Metabolism; | 1964 |
AMITRIPTYLINE AND IMIPRAMINE.
Topics: Amitriptyline; Depression; Depressive Disorder; Humans; Imipramine | 1964 |
DRUG MAINTENANCE PROBLEMS OF REHABILITATED MENTAL PATIENTS: THE CURRENT DRUG DOSAGE "MERRY-GO-ROUND".
Topics: Chlordiazepoxide; Chlorpromazine; Depression; Imipramine; Mental Disorders; Mentally Ill Persons; Pe | 1964 |
[LAROXYL (AMITRIPTYLINE), A THYMOLEPTIC WITH A NEUROLEPTIC EFFICACY COMPONENT].
Topics: Amitriptyline; Antidepressive Agents; Antipsychotic Agents; Bipolar Disorder; Chlordiazepoxide; Chlo | 1963 |
[PRESENT STATUS AND FUTURE POSSIBILITIES OF PHARMACOLOGICAL TREATMENT OF DEPRESSION].
Topics: Antidepressive Agents; Depression; Depressive Disorder; Humans; Imipramine; Monoamine Oxidase Inhibi | 1963 |
JAUNDICE DURING IMIPRAMINE TREATMENT.
Topics: Depression; Depressive Disorder; Imipramine; Jaundice; Toxicology | 1964 |
IMIPRAMINE AND THIORIDAZINE IN DEPRESSED AND SCHIZOPHRENIC PATIENTS. ARE THERE SPECIFIC ANTIDEPRESSANT DRUGS?
Topics: Amitriptyline; Antidepressive Agents; Chlorpromazine; Computers; Depression; Drug Therapy; Imipramin | 1964 |
[ON CHANGES IN THE FUNCTIONAL STATUS OF THE BRAIN AND THE ACTION OF PSYCHOPHARMACOLOGIC THERAPY IN ENDOGENOUS AND PSYCHOGENIC DEPRESSION].
Topics: Autonomic Nervous System; Bipolar Disorder; Brain; Depression; Depressive Disorder; Drug Therapy; Hu | 1963 |
DRUGS FOR DEPRESSION.
Topics: Amobarbital; Antidepressive Agents; Chlordiazepoxide; Depression; Depressive Disorder; Dextroampheta | 1964 |
ELECTROPLEXY IN FIRST ATTACKS OF DEPRESSION OVER THE AGE OF FIFTY.
Topics: Amitriptyline; Bipolar Disorder; Cerebrovascular Disorders; Depression; Depressive Disorder; Drug Th | 1964 |
GALACTORRHEA DUE TO IMIPRAMINE. REPORT OF A CASE.
Topics: Amenorrhea; Chlorpromazine; Depression; Depressive Disorder; Female; Galactorrhea; Humans; Hypothyro | 1964 |
[DESIPRAMINE (PERTOFRAN) IN THE TREATMENT OF DEPRESSIONS WITH A PSYCHODYNAMIC ANALYSIS OF ITS THERAPEUTIC EFFECTS].
Topics: Antidepressive Agents; Biomedical Research; Bipolar Disorder; Depression; Depressive Disorder; Desip | 1964 |
CHEMICAL REMEDIES FOR DEPRESSION.
Topics: Amitriptyline; Antidepressive Agents; Bipolar Disorder; Depression; Depressive Disorder; Hydrazines; | 1964 |
[TREATMENT OF DEPRESSION WITH TOFRANIL WITH REGARD TO THE DRAWING TEST].
Topics: Bipolar Disorder; Chlorpromazine; Depression; Depressive Disorder; Depressive Disorder, Major; Human | 1964 |
THE INFLUENCE OF MEDICATION (IMIPRAMINE) AND DOCTOR IN RELIEVING DEPRESSED PSYCHONEUROTIC OUTPATIENTS.
Topics: Biomedical Research; Depression; Depressive Disorder; Humans; Imipramine; Mental Health Services; Ou | 1964 |
[TREATMENT OF DEPRESSION].
Topics: Bipolar Disorder; Depression; Depressive Disorder; Electroconvulsive Therapy; Humans; Imipramine; Me | 1964 |
ON DEPRESSIVE REACTIONS.
Topics: Amitriptyline; Antidepressive Agents; Depression; Depressive Disorder; Drug Therapy; Electroconvulsi | 1964 |
[ON TOFRANIL TREATMENT OF DEPRESSIVE STATES IN PSYCHIATRIC PRACTICE WITH SPECIAL REFERENCE TO THE PROBLEM OF CONTINUOUS THERAPY].
Topics: Bipolar Disorder; Climacteric; Depression; Depressive Disorder; Imipramine; Psychotic Disorders; Sch | 1964 |
[PECULIARITIES OF THE PHOTOERYTHEMIC SKIN REACTION IN PATIENTS WITH MANIC-DEPRESSIVE CONDITIONS AND ITS DYNAMICS DURING THE COURSE OF TREATMENT].
Topics: Anxiety; Anxiety Disorders; Bipolar Disorder; Chlorpromazine; Depression; Depressive Disorder; Depre | 1963 |
[BARBAMYL-TOFRANIL TEST IN THE EVALUATION OF THE DEPRESSIVE STATE].
Topics: Amobarbital; Anxiety; Anxiety Disorders; Bipolar Disorder; Delirium; Delusions; Depression; Depressi | 1963 |
REPORT OF AN UNUSUALLY LARGE DOSAGE OF METHYLPHENIDATE HYDROCHLORIDE.
Topics: Alcoholic Beverages; Benactyzine; Depression; Depressive Disorder; Imipramine; Meprobamate; Methylph | 1964 |
THE CONTROLLED EVALUATION OF IMIPRAMINE AND AMITRIPTYLINE IN HOSPITALIZED DEPRESSED PSYCHIATRIC PATIENTS. A CONTRIBUTION TO THE METHODOLOGY OF DRUG EVALUATION.
Topics: Amitriptyline; Biomedical Research; Depression; Depressive Disorder; Drug Evaluation; Imipramine; Pl | 1964 |
SPECIFIC VALUE OF DRUGS IN PSYCHIATRIC ILLNESS.
Topics: Biomedical Research; Depression; Depressive Disorder; Imipramine; Mental Disorders; Psychopharmacolo | 1964 |
AMITRIPTYLINE IN DEPRESSIVE STATES: SIX-MONTH TREATMENT RESULTS.
Topics: Amitriptyline; Bipolar Disorder; Cardiovascular Diseases; Depression; Depressive Disorder; Drug Ther | 1964 |
THE PRACTICAL MANAGEMENT OF DEPRESSION.
Topics: Amitriptyline; Antidepressive Agents; Benzoates; Classification; Depression; Depressive Disorder; Dr | 1964 |
CONTROLLED COMPARISON OF AMITRIPTYLINE, IMIPRAMINE AND PLACEBO IN HOSPITALIZED DEPRESSED PATIENTS.
Topics: Amitriptyline; Depression; Depressive Disorder; Drug Therapy; Humans; Imipramine; MMPI; Placebos; Ps | 1964 |
THE INFLUENCE OF PATIENTS' ATTITUDES ON THEIR RESPONSE TO ANTIDEPRESSANT MEDICATION.
Topics: Antidepressive Agents; Attitude; Depression; Depressive Disorder; Drug Therapy; Humans; Imipramine; | 1964 |
AN EXPERIMENTAL STUDY OF WEIGHT CHANGES IN DEPRESSIONS.
Topics: Bipolar Disorder; Body Weight; Calcium; Calcium, Dietary; Depression; Diet; Drug Therapy; Electrocon | 1964 |
TRANSIENT BRAIN SYNDROME AS A NON-FATAL REACTION TO COMBINED PARGYLINE-IMIPRAMINE TREATMENT.
Topics: Brain; Depression; Depressive Disorder; Drug Therapy; Geriatrics; Hypertension; Imipramine; Mental D | 1964 |
AMITRIPTYLINE VERSUS IMIPRAMINE IN DEPRESSIVE PSYCHOSES.
Topics: Amitriptyline; Biomedical Research; Bipolar Disorder; Depression; Depressive Disorder; Depressive Di | 1964 |
A COMPARATIVE TRIAL OF IMIPRAMINE, AMITRIPTYLINE, ISOCARBOXAZID AND TRANYLCYPROMINE IN OUT-PATIENT DEPRESSIVE ILLNESS.
Topics: Amitriptyline; Biomedical Research; Depression; Depressive Disorder; Drug Therapy; Humans; Imipramin | 1964 |
COMPARISON OF DESIPRAMINE AND IMIPRAMINE IN DEPRESSION.
Topics: Biomedical Research; Depression; Depressive Disorder; Desipramine; Drug Therapy; Imipramine; Toxicol | 1964 |
EVALUATION OF NEWER ANTIDEPRESSANT DRUGS.
Topics: Amitriptyline; Antidepressive Agents; Biomedical Research; Depression; Depressive Disorder; Imiprami | 1964 |
EARLY RECOGNITION OF DEPRESSION.
Topics: Amitriptyline; Amphetamine; Amphetamines; Barbiturates; Benactyzine; Chlordiazepoxide; Deanol; Depre | 1964 |
NONOAMINE OXIDASE INHIBITORS VERSUS IMINODIBENZYL DERIVATIVES IN THE TREATMENT OF DEPRESSION. A COMPARATIVE CLINICAL STUDY OF IMPIRAMINE AND PHENIPRAZINE.
Topics: Benzylamines; Depression; Depressive Disorder; Drug Therapy; Electroconvulsive Therapy; Geriatrics; | 1964 |
DIFFERENTIAL THERAPEUTIC RESULTS OF THREE ANTIDEPRESSANT MEDICATIONS ACCORDING TO FIXED OR FUNCTIONAL SCHEDULES.
Topics: Antidepressive Agents; Biomedical Research; Depression; Depressive Disorder; Drug Therapy; Humans; I | 1964 |
ESCAPE FROM ENERGIZER CONTROL.
Topics: Amitriptyline; Depression; Humans; Imipramine; Mental Disorders; Monoamine Oxidase Inhibitors; Psych | 1965 |
A CASE OF POSTENCEPHALITIC PARKINSONISM RESPONDING TO COMBINED SURGICAL AND MEDICINAL TREATMENT.
Topics: Amitriptyline; Chlordiazepoxide; Depression; Depressive Disorder; Drug Therapy; Encephalitis; Eye Mo | 1965 |
VISUAL HALLUCINOSIS WHILE RECEIVING IMIPRAMINE.
Topics: Depression; Depressive Disorder; Drug Therapy; Geriatrics; Hallucinations; Imipramine; Psychopharmac | 1964 |
[SOMATOTHERAPY OF ENDOGENOUS PSYCHOSES AT MARBURG UNIVERSITY NEUROLOGIC CLINIC].
Topics: Bipolar Disorder; Chlordiazepoxide; Chlorpromazine; Chlorprothixene; Convulsive Therapy; Depression; | 1964 |
[IMIPRAMINE AND ELECTROSHOCK IN THE TREATMENT OF DEPRESSIONS].
Topics: Bipolar Disorder; Convulsive Therapy; Depression; Depressive Disorder; Drug Therapy; Electroconvulsi | 1964 |
[PROGRESS OF DEPRESSIVE DISEASES UNDER DRUG THERAPY].
Topics: Amitriptyline; Antidepressive Agents; Depression; Depressive Disorder; Desipramine; Drug Therapy; Hu | 1964 |
[ON AMBULATORY AND WARD MANAGEMENT OF DEPRESSIVE STATES WITH A DIBENZODIAZEPINE DERIVATIVE].
Topics: Amitriptyline; Antidepressive Agents; Depression; Depressive Disorder; Drug Therapy; Hypotension; Hy | 1964 |
PRACTICAL DRUG EVALUATION METHOD: IMIPRAMINE IN DEPRESSED OUTPATIENTS.
Topics: Amobarbital; Biomedical Research; Chlordiazepoxide; Chlorpromazine; Depression; Depressive Disorder; | 1965 |
COMBINING THE ANTIDEPRESSANT DRUGS.
Topics: Anorexia Nervosa; Antidepressive Agents; Depression; Depressive Disorder; Drug Therapy; Fever; Heada | 1965 |
[LATENT DEPRESSIVE SYNDROMES IN GENERAL MEDICINE (STUDY OF 100 CASES)].
Topics: Amitriptyline; Depression; Depressive Disorder; Drug Therapy; General Practice; Humans; Imipramine; | 1964 |
TREATMENT IN DEPRESSIVE ILLNESS.
Topics: Biomedical Research; Depression; Depressive Disorder; Drug Therapy; Imipramine; Phenelzine; Placebos | 1965 |
THE INFLUENCE OF CASE SELECTION AND DOSAGE IN AN ANTIDEPRESSANT DRUG TRIAL.
Topics: Amitriptyline; Antidepressive Agents; Biomedical Research; Depression; Depressive Disorder; Drug The | 1965 |
EXCRETION OF 3-METHOXY-4-HYDROXYMANDELIC ACID (VMA) IN DEPRESSED PATIENTS TREATED WITH ANTIDEPRESSANT DRUGS.
Topics: Antidepressive Agents; Biomedical Research; Depression; Depressive Disorder; Drug Therapy; Humans; I | 1964 |
ERECTILE IMPOTENCE DURING THE COURSE OF TOFRANIL THERAPY.
Topics: Depression; Depressive Disorder; Drug Therapy; Erectile Dysfunction; Humans; Imipramine; Male; Penis | 1965 |
TREATMENT OF DEPRESSION.
Topics: Amphetamine; Amphetamines; Antidepressive Agents; Catecholamines; Depression; Depressive Disorder; D | 1965 |
CHOICE OF SOMATIC THERAPIES IN DEPRESSION.
Topics: Biomedical Research; Depression; Depressive Disorder; Drug Therapy; Electroconvulsive Therapy; Imipr | 1964 |
EVALUATION OF EFFICACY OF IMIPRAMINE IN DEPRESSIVE DISORDERS: A DOUBLE-BLIND STUDY.
Topics: Biomedical Research; Depression; Depressive Disorder; Double-Blind Method; Drug Therapy; Imipramine; | 1965 |
THE DIAGNOSIS AND MANAGEMENT OF DEPRESSION.
Topics: Amitriptyline; Analgesics; Analgesics, Non-Narcotic; Antipyretics; Classification; Depression; Depre | 1965 |
THE MANAGEMENT OF DEPRESSION IN HOSPITAL. A COMPARATIVE TRIAL OF DESIPRAMINE AND IMIPRAMINE.
Topics: Biomedical Research; Depression; Depressive Disorder; Desipramine; Drug Therapy; Humans; Imipramine; | 1965 |
[PSYCHOPHARMACOLOGICAL EXPERIENCES WITH IMIPRAMINE, WITH SPECIAL REFERENCE TO LEONHARD'S CLASSIFICATION OF ENDOGENOUS PSYCHOSES].
Topics: Anxiety; Anxiety Disorders; Bipolar Disorder; Depression; Depressive Disorder; Drug Therapy; Humans; | 1964 |
POTENTIAL HAZARDS OF PSYCHOACTIVE DRUGS IN ASSOCIATION WITH ANAESTHESIA.
Topics: Adjuvants, Anesthesia; Amino Alcohols; Amitriptyline; Anesthesia; Antidepressive Agents; Depression; | 1965 |
LENGTH OF HOSPITALIZATION WITH VARIOUS TREATMENTS FOR DEPRESSION.
Topics: Aged; Bipolar Disorder; Depression; Depressive Disorder; Drug Therapy; Electroconvulsive Therapy; Ho | 1965 |
IMIPRAMINE-INDUCED AURICULAR FIBRILLATION.
Topics: Atrial Fibrillation; Depression; Depressive Disorder; Drug Therapy; Imipramine; Toxicology | 1965 |
[ADVANTAGE AND DISADVANTAGES OF AMBULANT THERAPY OF DEPRESSED SUBJECTS].
Topics: Depression; Depressive Disorder; Drug Therapy; Exercise Therapy; Humans; Imipramine | 1964 |
[MEDICAL ANTIDEPRESSIVE TREATMENT. NORTRIPTYLINE EVALUATED IN COMPARISON WITH AMITRIPTYLINE AND IMIPRAMINE].
Topics: Adolescent; Amitriptyline; Antidepressive Agents; Depression; Depressive Disorder; Geriatrics; Imipr | 1965 |
Humoral changes produced by tofranil and phenothiazine compounds.
Topics: Antipsychotic Agents; Depression; Humans; Imipramine; Phenothiazines; Schizophrenia; Tranquilizing A | 1959 |
[Clinical and theoretical aspects of psychotherapy of the depressive syndrome. I. Somatic effects of tofranil].
Topics: Depression; Depressive Disorder; Imipramine; Psychopharmacology; Psychotherapy | 1960 |
Indications for electro-shock, tofranil and psycho therapy in the treatment of depressions.
Topics: Convulsive Therapy; Depression; Depressive Disorder; Electroconvulsive Therapy; Humans; Imipramine; | 1959 |
[Experiences with tofranil in endogenous and reactive depressions].
Topics: Adjustment Disorders; Depression; Depressive Disorder; Imipramine; Psychopharmacology | 1960 |
Inpatient treatment of depressive states with tofranil (imipramine hydrochloride).
Topics: Depression; Depressive Disorder; Hospitalization; Humans; Imipramine; Inpatients; Tranquilizing Agen | 1959 |
Tofranil (imipramine) in the treatment of depressive states.
Topics: Depression; Depressive Disorder; Humans; Imipramine; Psychopharmacology | 1960 |
Depression therapy with imipramine hydrochloride.
Topics: Depression; Depressive Disorder; Imipramine; Psychopharmacology | 1960 |
[Imipramine treatment of depressions].
Topics: Depression; Depressive Disorder; Imipramine; Psychopharmacology | 1960 |
Negative results in the treatment of depression with imipramine hydrochloride (tofranil).
Topics: Depression; Depressive Disorder; Imipramine; Tranquilizing Agents | 1959 |
The treatment of depressive states with imipramine hydrochloride (tofranil).
Topics: Depression; Depressive Disorder; Imipramine; Tranquilizing Agents | 1959 |
Out-patient treatment of depression with imipramine ("tofranil"): a prelimiary report.
Topics: Ambulatory Care; Depression; Depressive Disorder; Humans; Imipramine; Outpatients; Psychopharmacolog | 1960 |
[Treatment of depressive states with tofranil].
Topics: Depression; Depressive Disorder; Imipramine; Psychopharmacology | 1959 |
Preliminary evaluation of tofranil in a combined in-patient and out-patient setting.
Topics: Depression; Depressive Disorder; Imipramine; Outpatients; Tranquilizing Agents | 1959 |
Imipramine, a clinical evaluation in a variety of settings.
Topics: Depression; Depressive Disorder; Imipramine; Psychopharmacology | 1960 |
The treatment of depressive states with particular reference to imipramine.
Topics: Depression; Depressive Disorder; Imipramine; Psychopharmacology | 1960 |
[Action of tofranil in chronic depressive states. Value of maintenance treatments].
Topics: Depression; Depressive Disorder; Imipramine; Psychopharmacology | 1960 |
[Tofranil in the clinical therapy of melancholia].
Topics: Depression; Depressive Disorder; Imipramine; Psychopharmacology | 1960 |
[Experiences with the tofranil treatment of depressive states].
Topics: Depression; Depressive Disorder; Imipramine; Psychopharmacology | 1959 |
Clinical findings in the use of tofranil in depressive and other psychiatric states.
Topics: Depression; Depressive Disorder; Imipramine; Tranquilizing Agents | 1959 |
[Treatment of melancholic states with new chemotherapy agents: levomepromazine, imipramine, iproniazid, reserpine, deprol].
Topics: Antineoplastic Agents; Depression; Depressive Disorder; Imipramine; Iproniazid; Methotrimeprazine; P | 1959 |
[A contribution to the treatment of depressive states with tofranil].
Topics: Depression; Depressive Disorder; Imipramine; Psychopharmacology | 1960 |
[The iminodibenzyl derivative G22355 (tofranil) in 100 depressed patients].
Topics: Benzylamines; Depression; Depressive Disorder; Imipramine; Tranquilizing Agents | 1959 |
[On the tofranil therapy of depressive states. A contribution to the optimal use of pharmacopsychiatric medications].
Topics: Depression; Depressive Disorder; Imipramine; Psychopharmacology | 1960 |
[Therapeutic results from the use of a new iminodibenzyl derivative (tofranil) in depressive syndromes].
Topics: Benzylamines; Depression; Depressive Disorder; Imipramine; Tranquilizing Agents | 1959 |
Effect of tofranil on certain aspects of the depressive syndrome.
Topics: Depression; Depressive Disorder; Imipramine; Tranquilizing Agents | 1959 |
[The treatment of depressive states with imipramine (tofranil) and iproniazid (marsilid)].
Topics: Depression; Depressive Disorder; Imipramine; Iproniazid; Psychopharmacology | 1959 |
Report of hypomanic excitement with imipramine treatment of depression.
Topics: Bipolar Disorder; Cyclothymic Disorder; Depression; Depressive Disorder; Humans; Imipramine; Psychop | 1960 |
[Results of therapy of depression with imipramine].
Topics: Depression; Depressive Disorder; Imipramine; Psychopharmacology | 1960 |
[Therapeutic action of imipramine in a group of depressive states. Apropos of 50 cases].
Topics: Depression; Depressive Disorder; Imipramine; Psychopharmacology | 1960 |
Problems of ambulant drug therapy of depression.
Topics: Depression; Depressive Disorder; Imipramine; Monoamine Oxidase Inhibitors | 1961 |
[Effects of psychoanaleptic drugs on normal individuals, with special regard to differential action of imipramine upon normal and depressive conditions].
Topics: Central Nervous System Stimulants; Depression; Depressive Disorder; Imipramine | 1962 |
A comparison of treatment of endogenous depression with electroshock and with imipramine (tofranil).
Topics: Convulsive Therapy; Depression; Depressive Disorder; Electricity; Electroconvulsive Therapy; Electro | 1961 |
[Apropos of a new antidepressant: Ro 4-1575].
Topics: Antidepressive Agents; Depression; Depressive Disorder; Imipramine | 1962 |
Behavioral evaluation of imipramine and nialamide in regressed schizophrenic patients with depressive features.
Topics: Depression; Depressive Disorder; Imipramine; Iproniazid; Nialamide; Psychopharmacology; Schizophreni | 1961 |
[On preventive long-term therapy of depressions. A preliminary report].
Topics: Depression; Depressive Disorder; Imipramine | 1962 |
The target symptoms in the treatment of depressions.
Topics: Depression; Depressive Disorder; Humans; Imipramine | 1962 |
Desmethylimipramine (G-35020) in the treatment of depression, pilot study in a general hospital and outpatient setting.
Topics: Depression; Depressive Disorder; Desipramine; Hospitals, General; Imipramine; Outpatients; Pilot Pro | 1962 |
Elavil in the treatment of affective disorders (and comparison with tofranil).
Topics: Amitriptyline; Depression; Depressive Disorder; Imipramine; Mood Disorders; Psychopharmacology | 1961 |
Preliminary investigation of desmethylimipramine (G 35020).
Topics: Depression; Depressive Disorder; Desipramine; Imipramine | 1962 |
CPT and VCRT performances as functions of imipramine and nialamide.
Topics: Biological Psychiatry; Depression; Depressive Disorder; Humans; Imipramine; Iproniazid; Nialamide; P | 1962 |
Imipramine-promazine therapy for depression.
Topics: Depression; Depressive Disorder; Imipramine; Promazine | 1962 |
Hypericum perforatum subspecies angustifolium shows a protective activity on the consequences of unavoidable stress exposure at lower doses than Hypericum perforatum perforatum.
Topics: Animals; Antidepressive Agents; Bridged Bicyclo Compounds; Depression; Disease Models, Animal; Dose- | 2003 |
Antidepressant activity of quercetin, a bioflavonoid, in streptozotocin-induced diabetic mice.
Topics: Animals; Antidepressive Agents; Depression; Diabetes Mellitus, Experimental; Disease Models, Animal; | 2003 |
Is agmatine an endogenous anxiolytic/antidepressant agent?
Topics: Agmatine; Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Behavior, Animal; Depression | 2003 |
Harmane induces anxiolysis and antidepressant-like effects in rats.
Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Behavior, Animal; Depression; Dose-Res | 2003 |
Effect of combined administration of 5-HT1A or 5-HT1B/1D receptor antagonists and antidepressants in the forced swimming test.
Topics: Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Cita | 2004 |
[Effect of total triterpenes from Centella asiatica on the depression behavior and concentration of amino acid in forced swimming mice].
Topics: Amino Acids; Animals; Antidepressive Agents; Brain; Centella; Depression; Dose-Response Relationship | 2003 |
Long-term imipramine withdrawal induces a depressive-like behaviour in the forced swimming test.
Topics: Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Depression; Disease Models, Animal; Imi | 2004 |
Eugenol exhibits antidepressant-like activity in mice and induces expression of metallothionein-III in the hippocampus.
Topics: alpha-MSH; Animals; Antidepressive Agents; Behavior, Animal; Brain-Derived Neurotrophic Factor; Depr | 2004 |
Phosphatidylserine: an antidepressive or a cognitive enhancer?
Topics: Animals; Antidepressive Agents; Cognition; Depression; Imipramine; Male; Maze Learning; Memory, Shor | 2004 |
Reduced anxiety and depression-like behavior in synaptotagmin IV (-/-) mice.
Topics: Animals; Anxiety; Calcium-Binding Proteins; Depression; Female; Imipramine; Male; Membrane Glycoprot | 2004 |
PSYCHOTHERAPEUTIC DRUGS IN THE TREATMENT OF DEPRESSIONS.
Topics: Amitriptyline; Amphetamine; Amphetamines; Antidepressive Agents; Depression; Electroconvulsive Thera | 1963 |
[Effect of madecassoside on depression behavior of mice and activities of MAO in different brain regions of rats].
Topics: Animals; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Brain; Depression; Imipramine; Male | 2004 |
Does rat global transient cerebral ischemia serve as an appropriate model to study emotional disturbances?
Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Anxiety; Depression; Diazepam; Disea | 2004 |
Acquired deficit of forebrain glucocorticoid receptor produces depression-like changes in adrenal axis regulation and behavior.
Topics: Animals; Corticotropin-Releasing Hormone; Depression; Hippocampus; Hypothalamo-Hypophyseal System; I | 2005 |
Antidepressant effect of Chaihu-Shugan-San extract and its constituents in rat models of depression.
Topics: Administration, Oral; Animals; Antidepressive Agents; Depression; Disease Models, Animal; Imipramine | 2005 |
Stressed and depressed.
Topics: Animals; Antidepressive Agents, Tricyclic; Depression; Humans; Imipramine; Mice; Mice, Knockout; Rec | 2005 |
Influence of imipramine on the duration of immobility in chronic forced-swim-stressed rats.
Topics: Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Depression; Imipramine; Male; Rats; Rat | 2004 |
Serotonergic activity and the Beck Depression Inventory in the premenstrual syndrome.
Topics: Adolescent; Adrenergic Uptake Inhibitors; Adult; Case-Control Studies; Depression; Female; Humans; I | 2005 |
Cell proliferation is influenced by bulbectomy and normalized by imipramine treatment in a region-specific manner.
Topics: Amygdala; Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Bromodeoxyuridine; Cell Proli | 2006 |
Differential gender-related vulnerability to depression induction and converging antidepressant responses in rats.
Topics: Animals; Antidepressive Agents, Tricyclic; Avoidance Learning; Behavior, Animal; Brain-Derived Neuro | 2006 |
Antidepressant-like effect of hyperbaric oxygen treatment in forced-swimming test in rats.
Topics: Animals; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Depression; Flu | 2005 |
Evaluation of two genetic animal models in behavioral tests of anxiety and depression.
Topics: Animals; Antidepressive Agents, Tricyclic; Anxiety; Behavior, Animal; Depression; Factor Analysis, S | 2006 |
Late developmental stage-specific role of tryptophan hydroxylase 1 in brain serotonin levels.
Topics: Animals; Antidepressive Agents; Biopterins; Brain; Chlorocebus aethiops; COS Cells; Depression; Enzy | 2006 |
Essential role of BDNF in the mesolimbic dopamine pathway in social defeat stress.
Topics: Aggression; Animals; Antidepressive Agents; Brain-Derived Neurotrophic Factor; Depression; Dominance | 2006 |
Neonatal citalopram exposure produces lasting changes in behavior which are reversed by adult imipramine treatment.
Topics: Adrenergic Uptake Inhibitors; Animals; Animals, Newborn; Antidepressive Agents, Tricyclic; Behavior, | 2006 |
Sustained hippocampal chromatin regulation in a mouse model of depression and antidepressant action.
Topics: Acetylation; Animals; Antidepressive Agents; Behavior, Animal; Brain-Derived Neurotrophic Factor; Ch | 2006 |
Even chromatin gets the blues.
Topics: Alternative Splicing; Animals; Antidepressive Agents; Brain-Derived Neurotrophic Factor; Chromatin; | 2006 |
Synthesis and antidepressant-like action of stereoisomers of imidobenzenesulfonylaziridines in mice evaluated in the forced swimming test.
Topics: Alkaloids; Animals; Antidepressive Agents; Aziridines; Behavior, Animal; Depression; Disease Models, | 2006 |
Effect of antidepressant drugs on 6-OHDA-treated mice in the FST.
Topics: Animals; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tri | 2007 |
Putrescine produces antidepressant-like effects in the forced swimming test and in the tail suspension test in mice.
Topics: Agmatine; Animals; Antidepressive Agents; Depression; Disease Models, Animal; Female; Imipramine; Im | 2006 |
Effect of the selective 5-HT7 receptor antagonist SB 269970 in animal models of anxiety and depression.
Topics: Analysis of Variance; Animals; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Anxiety; Behav | 2006 |
Imipramine-induced facial pigmentation: case report and literature review.
Topics: Adrenergic Uptake Inhibitors; Adult; Aged; Antidepressive Agents, Tricyclic; Depression; Facial Derm | 2005 |
Imipramine and citalopram reverse corticosterone-induced alterations in the effects of the activation of 5-HT(1A) and 5-HT(2) receptors in rat frontal cortex.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Antidepressive Agents, Second-Generat | 2006 |
Modeling the anxiety-depression continuum hypothesis in domestic fowl chicks.
Topics: Animals; Animals, Newborn; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Anxiety; Chickens; | 2006 |
Long-term behavioral changes after cessation of chronic antidepressant treatment in olfactory bulbectomized rats.
Topics: Analysis of Variance; Animals; Antidepressive Agents; Behavior, Animal; Citalopram; Depression; Dise | 2007 |
Treatment of postpsychotic depression with sertraline in patients with schizophrenia--own experience.
Topics: Adult; Antidepressive Agents; Antidepressive Agents, Tricyclic; Depression; Female; Humans; Imiprami | 2006 |
The influence of n-6 fatty acid supplemented diet on the effect of imipramine in an animal model of depression.
Topics: Animals; Antidepressive Agents, Tricyclic; Body Weight; Catecholamines; Chromatography, High Pressur | 2007 |
Effects of the brain-penetrant and selective 5-HT6 receptor antagonist SB-399885 in animal models of anxiety and depression.
Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Antidepressive Agents, Tricyclic; Anxiety; Avoi | 2007 |
Enriched environments influence depression-related behavior in adult mice and the survival of newborn cells in their hippocampi.
Topics: Animals; Antidepressive Agents, Tricyclic; Cell Survival; Depression; Disease Models, Animal; Enviro | 2007 |
Role of alpha2 receptors in quercetin-induced behavioral despair in mice.
Topics: Adrenergic alpha-Antagonists; Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Depressio | 2007 |
Hypothalamus-pituitary-adrenal modifications consequent to chronic stress exposure in an experimental model of depression in rats.
Topics: Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Corticosterone; Corticotropin-Releasing | 2007 |
Activation of the mGlu7 receptor elicits antidepressant-like effects in mice.
Topics: Analysis of Variance; Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Benzhydryl Compou | 2007 |
Imipramine reverses the depressive symptoms in sepsis survivor rats.
Topics: Animals; Antidepressive Agents, Tricyclic; Brazil; Depression; Imipramine; Prospective Studies; Rats | 2007 |
Anxiolytic-like and antidepressant-like effects produced by the selective 5-HT6 receptor antagonist SB-258585 after intrahippocampal administration to rats.
Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Depression; Diazepam; Disease Models, | 2007 |
Repeated social defeat-induced depression-like behavioral and biological alterations in rats: involvement of cholecystokinin.
Topics: Analysis of Variance; Animals; Antidepressive Agents, Tricyclic; Bromodeoxyuridine; Cell Proliferati | 2008 |
Conditional generalized estimating equations for the analysis of clustered and longitudinal data.
Topics: Antidepressive Agents, Tricyclic; Biometry; Clinical Trials as Topic; Cluster Analysis; Data Interpr | 2008 |
Antidepressant-like effect of agmatine is not mediated by serotonin.
Topics: Agmatine; Analysis of Variance; Animals; Antidepressive Agents; Behavior, Animal; Depression; Diseas | 2008 |
Dopamine-dependent nature of depression-like behavior in WAG/Rij rats with genetic absence epilepsy.
Topics: Animals; Antidepressive Agents, Tricyclic; Bromocriptine; Depression; Dopamine; Dopamine Agonists; D | 2008 |
Chronic coadministration of carbamazepine together with imipramine produces antidepressant-like effects in an ACTH-induced animal model of treatment-resistant depression: involvement of 5-HT(2A) receptors?
Topics: Adrenocorticotropic Hormone; Amphetamines; Animals; Antidepressive Agents; Carbamazepine; Depression | 2008 |
Chronic low dose corticosterone exposure decreased hippocampal cell proliferation, volume and induced anxiety and depression like behaviours in mice.
Topics: Adrenal Glands; Animals; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; | 2008 |
The creation of the concept of an antidepressant: an historical analysis.
Topics: Antidepressive Agents; Depression; Drug Industry; Drug Therapy; History, 20th Century; Humans; Imipr | 2008 |
Antidepressant effect of Yueju-Wan ethanol extract and its fractions in mice models of despair.
Topics: 1-Butanol; Acetates; Animals; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antid | 2008 |
Pharmacokinetic and pharmacodynamic studies of drug interaction following oral administration of imipramine and sodium alginate in rats.
Topics: Administration, Oral; Alginates; Animals; Antidepressive Agents, Tricyclic; Area Under Curve; Depres | 2008 |
[Experience with the use of acrichine in patients in depressive states and catatonis(preliminary report)].
Topics: Adjustment Disorders; Adolescent; Adult; Antidepressive Agents; Bipolar Disorder; Catatonia; Chlorpr | 1966 |
[Psychopathological complications in antidepressant medication].
Topics: Amitriptyline; Animals; Antidepressive Agents; Blood Pressure; Delirium; Depression; Desipramine; Do | 1966 |
[Changes in the oxygen deficiency tolerance in man induced by psychopharmaca].
Topics: Depression; Humans; Hypoxia; Imipramine | 1966 |
[Therapeutic experiences in 5 clinics with a dibenzoxepine derivative in depressive states].
Topics: Amitriptyline; Depression; Desipramine; Dibenzothiepins; Dibenzoxepins; Humans; Imipramine; Monoamin | 1966 |
[Comparative clinical experiences with Protriptyline in depressive conditions of various origins].
Topics: Amitriptyline; Antidepressive Agents; Depression; Desipramine; Dibenzazepines; Humans; Imipramine; N | 1966 |
Depression in acute schizophrenic psychosis.
Topics: Antidepressive Agents; Depression; Electroconvulsive Therapy; Female; Humans; Imipramine; Male; Phen | 1967 |
Autonomic reactions in relation to psychotropic drugs.
Topics: Adolescent; Adult; Autonomic Nervous System; Blood Pressure; Chlorpromazine; Darkness; Depression; F | 1967 |
Methodological formalism in psychiatric research.
Topics: Depression; Humans; Imipramine; Psychiatry; Research; Smoking; Statistics as Topic | 1967 |
Differences in cognitive status between healthy, psychiatrically ill, and diffusely brain-damaged elderly subjects.
Topics: Aged; Brain Damage, Chronic; Depression; Electroconvulsive Therapy; Female; Humans; Imipramine; Inte | 1967 |
Guides to appropriate drug therapy of depressed patients.
Topics: Adult; Aged; Amitriptyline; Depression; Humans; Imipramine; Middle Aged | 1967 |
Psychopharmacology is a hybrid science.
Topics: Depression; Humans; Imipramine | 1967 |
[Statistical study of case histories of depression treated with Surmontil].
Topics: Adolescent; Adult; Aged; Antidepressive Agents; Child; Child, Preschool; Depression; Female; Humans; | 1967 |
Rehabilitation following laryngectomy.
Topics: Amitriptyline; Depression; Electroconvulsive Therapy; Humans; Imipramine; Laryngeal Neoplasms; Laryn | 1967 |
[Thromboembolism complications in neuro- and thymoleptic therapy].
Topics: Adolescent; Adult; Amitriptyline; Antidepressive Agents; Chlorpromazine; Depression; Female; Humans; | 1967 |
[Clinical studies of a new antidepressive agent, nortriptyline].
Topics: Adolescent; Adult; Aged; Amitriptyline; Depression; Desipramine; Humans; Imipramine; Middle Aged; Ne | 1967 |
[Place of nortriptyline in the group of antidepressants; clinical and electroencephalographic considerations].
Topics: Amitriptyline; Depression; Humans; Imipramine; Nortriptyline | 1967 |
[The therapy of depressions with Trimeprimine, a methylated imipramine].
Topics: Adult; Aged; Animals; Depression; Female; Humans; Imipramine; Male; Methylation; Middle Aged | 1967 |
Dexamethasone suppression test identifies subtypes of depression which respond to different antidepressants.
Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Clomipramine; Depression; Depression, Chemic | 1980 |
Biochemistry and treatment strategies for depression.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Depression; Humans; Imipramine; Neurotransmitter Ag | 1980 |
Alprazolam in a biochemical model of depression.
Topics: Alprazolam; Animals; Anti-Anxiety Agents; Benzodiazepines; Depression; Diazepam; Disease Models, Ani | 1982 |
Comparison of alprazolam with imipramine and placebos.
Topics: Alprazolam; Anti-Anxiety Agents; Benzodiazepines; Depression; Humans; Imipramine | 1984 |
Adaptive changes as the mode of action of antidepressant treatments.
Topics: Adaptation, Physiological; Animals; Antidepressive Agents; Chlorprothixene; Depression; Electroshock | 1982 |
Relevance of tryptophan and tyrosine availability in endogenous and 'non-endogenous' depressives treated with imipramine or clomipramine.
Topics: Biological Availability; Clomipramine; Depression; Depressive Disorder; Humans; Imipramine; Time Fac | 1981 |
[N-dealkylation of chlorimipramine and chlorpromazine in patients undergoing chronic treatment with both drugs: preliminary results].
Topics: Chlorpromazine; Clomipramine; Depression; Dissociative Disorders; Humans; Imipramine | 1984 |
Evaluation of a proposed hamster separation model of depression.
Topics: Animals; Behavior, Animal; Body Weight; Cricetinae; Depression; Disease Models, Animal; Exploratory | 1984 |
[Role of the amygdala in the sedation induced by low doses of apomorphine].
Topics: Amygdala; Animals; Apomorphine; Depression; Humans; Imipramine; Motor Activity; Rats; Rats, Inbred S | 1983 |
Effects of chronic treatment with imipramine, trazodone and electroshock on the behavioural and electroencephalographic modifications induced by clonidine in the rat.
Topics: Animals; Behavior, Animal; Brain; Clonidine; Depression; Disease Models, Animal; Electroencephalogra | 1983 |
Serum dopamine-beta-hydroxylase activity in depression and anxiety.
Topics: Adult; Aged; Alprazolam; Anxiety; Anxiety Disorders; Benzodiazepines; Depression; Depressive Disorde | 1984 |
Endogenous depression and imipramine levels in the blood.
Topics: Adult; Aged; Depression; Desipramine; Female; Humans; Imipramine; Kinetics; Male; Middle Aged; Psych | 1980 |
3H-imipramine binding and serotonin uptake in platelets from untreated depressed patients and control volunteers.
Topics: Adult; Aged; Blood Platelets; Depression; Female; Humans; Imipramine; Kinetics; Male; Middle Aged; S | 1982 |
Depression in children. Effects of antidepressant therapy.
Topics: Antidepressive Agents, Tricyclic; Child; Depression; Female; Humans; Imipramine; Male | 1983 |
Clinical utility of tricyclic blood levels.
Topics: Delirium; Depression; Female; Humans; Imipramine; Middle Aged; Monitoring, Physiologic | 1980 |
Postsynaptic action by four antidepressive drugs in an animal model of depression.
Topics: 5-Hydroxytryptophan; Amitriptyline; Animals; Antidepressive Agents; Behavior, Animal; Depression; Di | 1981 |
Plasma imipramine concentrations in patients receiving concomitant fluphenazine decanoate.
Topics: Adult; Delayed-Action Preparations; Depression; Drug Interactions; Drug Therapy, Combination; Female | 1982 |
Imipramine disposition in alcoholics.
Topics: Administration, Oral; Adolescent; Adult; Alcoholism; Chromatography, High Pressure Liquid; Depressio | 1982 |
On the clinical response/serum level relationship for antidepressants II: Lofepramine and imipramine.
Topics: Depression; Dibenzazepines; Humans; Imipramine; Lofepramine | 1982 |
Normalization of platelet [3H]imipramine binding in depressed patients during remission.
Topics: Blood Platelets; Depression; Humans; Imipramine; Patient Readmission; Tritium | 1982 |
[Effects of thymo-analeptics and acceptability of amineptin compared to those of imipramine].
Topics: Adolescent; Adult; Aged; Antidepressive Agents, Tricyclic; Depression; Dibenzocycloheptenes; Double- | 1982 |
Relationship between regional distribution of imipramine and its effect on learned helplessness in the rat.
Topics: Animals; Behavior, Animal; Depression; Disease Models, Animal; Escape Reaction; Humans; Imipramine; | 1980 |
Electromyographic assessment of spinal reflexes in experimentally depressed dogs treated with antidepressants.
Topics: Amitriptyline; Animals; Depression; Dogs; Electromyography; Hindlimb; Humans; Imipramine; Male; Moto | 1980 |
Further studies on a novel animal model of depression: therapeutic effects of a tricyclic antidepressant.
Topics: Acute Disease; Animals; Chronic Disease; Corticosterone; Defecation; Depression; Disease Models, Ani | 1981 |
Ejaculatory impairment from both phenelzine and imipramine, with tinnitus from phenelzine.
Topics: Depression; Ejaculation; Female; Humans; Imipramine; Male; Middle Aged; Phenelzine; Sexual Dysfuncti | 1981 |
Evaluation and multimodality treatment of a depressed prepubertal girl.
Topics: Child; Depression; Female; Humans; Imipramine; Psychotherapy | 1980 |
The depression-pain syndrome and its response to antidepressants.
Topics: Adolescent; Adult; Aged; Amitriptyline; Antidepressive Agents; Depression; Desipramine; Doxepin; Fem | 1981 |
High-affinity binding of 3H-imipramine in brain and platelets and its relevance to the biochemistry of affective disorders.
Topics: Animals; Binding Sites; Blood Platelets; Brain; Depression; Humans; Imipramine; Mood Disorders | 1981 |
Uptake of 5-hydroxytryptamine by blood platelets incubated in plasma from rats and humans treated with amitriptyline and imipramine.
Topics: Amitriptyline; Animals; Biological Assay; Blood Platelets; Chromatography, Gas; Depression; Depressi | 1981 |
Withdrawal symptoms during the course of imipramine therapy.
Topics: Adult; Depression; Drug Administration Schedule; Female; Humans; Imipramine; Male; Substance Withdra | 1980 |
Lack of anticholinergic side effects with a new antidepressent--trazodone.
Topics: Adult; Aged; Constipation; Depression; Double-Blind Method; Female; Humans; Imipramine; Male; Middle | 1980 |
Triiodothyronine, imipramine, and depression.
Topics: Depression; Drug Therapy, Combination; Female; Humans; Imipramine; Male; Triiodothyronine | 1980 |
Investigations on electrolyte and water contents in plasma and red blood cells in the course of thymoleptic treatment of depressive syndromes.
Topics: Adult; Body Water; Calcium; Depression; Electrolytes; Erythrocytes; Female; Humans; Imipramine; Magn | 1980 |
Lithium treatment and prophylaxis in unipolar depression.
Topics: Acute Disease; Depression; Humans; Imipramine; Lithium; Maprotiline; Recurrence | 1980 |
Tritiated imipramine binding sites are decreased in platelets of untreated depressed patients.
Topics: Adult; Aged; Blood Platelets; Cell Membrane; Depression; Humans; Imipramine; Kinetics; Middle Aged; | 1980 |
[Haloperidol-induced akathisia in the state of violence].
Topics: Depression; Haloperidol; Humans; Imipramine; Motor Activity; Violence | 1980 |
Quantitative analysis for tricyclic antidepressant drugs in plasma or serum by gas chromatography-chemical-ionization mass spectrometry.
Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Depression; Desipramine; Female; Gas Chromat | 1980 |
Decrease in speech pause times with treatment of endogenous depression.
Topics: Adult; Aged; Amitriptyline; Bipolar Disorder; Depression; Drug Therapy, Combination; Electroconvulsi | 1980 |
The differential effects of viloxazine and imipramine on performance tests: their relationship to behavioural toxicity.
Topics: Depression; Double-Blind Method; Humans; Imipramine; Morpholines; Motor Skills; Viloxazine | 1980 |
A placebo-controlled double-blind study of imipramine and trazodone in geriatric depression.
Topics: Age Factors; Aged; Depression; Double-Blind Method; Female; Humans; Imipramine; Male; Middle Aged; P | 1980 |
Clinical and biological aspects of depression in the elderly.
Topics: Aged; Dementia; Depression; Doxepin; Humans; Imipramine; Methylphenidate; Middle Aged; Trazodone | 1980 |
[3H]-Imipramine binding in human platelets: a new biochemical parameter in depression.
Topics: Blood Platelets; Depression; Female; Humans; Imipramine; In Vitro Techniques; Kinetics; Male | 1980 |
[Decompensation of glaucoma after administration of tricyclic antidepressants and anxiolytic drugs].
Topics: Amitriptyline; Depression; Female; Glaucoma; Humans; Imipramine; Intraocular Pressure; Middle Aged; | 1980 |
Implication of endogenous opioid system in the learned helplessness model of depression.
Topics: Animals; Antidepressive Agents, Tricyclic; Avoidance Learning; Depression; Electroshock; Endorphins; | 1995 |
The effect of chronic treatment with imipramine on the responsiveness of hippocampal CA1 neurons to phenylephrine and serotonin in a chronic mild stress model of depression.
Topics: Animals; Depression; Disease Models, Animal; Hippocampus; Imipramine; Male; Neurons; Phenylephrine; | 1995 |
Pseudoephedrine and imipramine for depression.
Topics: Adult; Depression; Ephedrine; Humans; Imipramine; Male | 1994 |
Pseudoephedrine and imipramine for depression--grounds for caution?
Topics: Depression; Drug Therapy, Combination; Ephedrine; Humans; Imipramine | 1995 |
Antidepressant-like effect of selective dopamine D1 receptor agonists in the behavioural despair animal model of depression.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Analysis of Variance; Animals; Antidepre | 1994 |
Antidepressant activity of non-competitive and competitive NMDA receptor antagonists in a chronic mild stress model of depression.
Topics: 2-Amino-5-phosphonovalerate; Animals; Depression; Dizocilpine Maleate; Imipramine; Injections, Intra | 1994 |
Antidepressant activity of non-competitive and competitive NMDA receptor antagonists in a chronic mild stress model of depression.
Topics: 2-Amino-5-phosphonovalerate; Animals; Depression; Dizocilpine Maleate; Imipramine; Injections, Intra | 1994 |
Antidepressant activity of non-competitive and competitive NMDA receptor antagonists in a chronic mild stress model of depression.
Topics: 2-Amino-5-phosphonovalerate; Animals; Depression; Dizocilpine Maleate; Imipramine; Injections, Intra | 1994 |
Antidepressant activity of non-competitive and competitive NMDA receptor antagonists in a chronic mild stress model of depression.
Topics: 2-Amino-5-phosphonovalerate; Animals; Depression; Dizocilpine Maleate; Imipramine; Injections, Intra | 1994 |
Effects of imipramine on serotonergic and beta-adrenergic receptor binding in a realistic animal model of depression.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Depression; Dihydroalprenolol; Im | 1994 |
TJS-010, a new prescription of Kampo medicine with putative antidepressive and anxiolytic properties.--A behavioral study using experimental models for depression and anxiety.
Topics: Administration, Oral; Animals; Anxiety; Depression; Disease Models, Animal; Drugs, Chinese Herbal; H | 1994 |
Decreased plasma concentrations of imipramine and desipramine following cholestyramine intake in depressed patients.
Topics: Adult; Cholestyramine Resin; Depression; Desipramine; Drug Interactions; Female; Humans; Imipramine; | 1994 |
Reversal by imipramine of beta-adrenoceptor up-regulation induced in a chronic mild stress model of depression.
Topics: Adenylyl Cyclases; Adrenergic beta-Antagonists; Animals; Cerebral Cortex; Chronic Disease; Depressio | 1994 |
Multiple drug overdose in a kidney transplant patient.
Topics: Chromatography, Thin Layer; Cyclosporine; Depression; Drug Overdose; Half-Life; Humans; Imipramine; | 1994 |
Changes in basal and stimulated release of endogenous serotonin from different nuclei of rats subjected to two models of depression.
Topics: Animals; Brain Chemistry; Depression; Hippocampus; Imipramine; Male; Nucleus Accumbens; Potassium Ch | 1993 |
Evaluation of depression in rats exposed to chronic (unpredictable) electric shock.
Topics: Animals; Behavior, Animal; Conditioning, Operant; Depression; Diazepam; Electroshock; Helplessness, | 1993 |
Depletion of mesolimbic dopamine during behavioral despair: partial reversal by chronic imipramine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Depression; Disease Models, Animal; Dopami | 1993 |
Prospective study of the electrocardiographic effects of imipramine in children.
Topics: Adolescent; Child; Child Behavior Disorders; Child, Preschool; Depression; Electrocardiography; Elec | 1993 |
Juvenile desipramine reduces adult sensitivity to imipramine in two behavioral tests.
Topics: Animals; Behavior, Animal; Defecation; Depression; Desipramine; Female; Imipramine; Motor Activity; | 1993 |
Desensitization of the D1 dopamine receptors in rats reproduces a model of escape deficit reverted by imipramine, fluoxetine and clomipramine.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Clomipramine; Depression; Disea | 1995 |
The effect of chronic treatment with imipramine on the immunoreactivity of animals subjected to a chronic mild stress model of depression.
Topics: Animals; Antidepressive Agents, Tricyclic; Depression; Imipramine; Lymphocyte Activation; Male; Rats | 1995 |
Study addresses question of preferred initial therapy for depression.
Topics: Antidepressive Agents, Tricyclic; Cost-Benefit Analysis; Depression; Desipramine; Drug Costs; Fluoxe | 1996 |
SSRI or tricyclics for depression?
Topics: Adult; Depression; Depressive Disorder; Desipramine; Family Practice; Fluoxetine; Humans; Imipramine | 1996 |
Potential antidepressant effects of lemon odor in rats.
Topics: Animals; Antidepressive Agents; Citrus; Depression; Desipramine; Imipramine; Male; Motor Activity; O | 1995 |
Protective effect of citalopram against the attenuation of the alpha 1-potentiation of cAMP formation in Fischer 344 strain rats.
Topics: Adrenergic Uptake Inhibitors; Animals; Behavior, Animal; Body Weight; Brain Chemistry; Citalopram; C | 1997 |
Influence of antidepressant drugs on learning and memory paradigms in mice.
Topics: Aged; Amitriptyline; Animals; Antidepressive Agents; Depression; Female; Fluoxetine; Humans; Imipram | 1996 |
Antidepressant-like effects of CP-154,526, a selective CRF1 receptor antagonist.
Topics: Analysis of Variance; Animals; Antidepressive Agents, Tricyclic; Depression; Disease Models, Animal; | 1997 |
Chronic imipramine treatment upregulates IR2-imidazoline receptive sites in rat brain.
Topics: Animals; Antidepressive Agents; Brain; Cell Membrane; Depression; Idazoxan; Imidazoline Receptors; I | 1997 |
Effects of hypericum extract (LI 160) in biochemical models of antidepressant activity.
Topics: Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Brai | 1997 |
Tricyclic poisoning--successful management of ventricular fibrillation following massive overdose of imipramine.
Topics: Adrenergic Agonists; Adult; Anti-Arrhythmia Agents; Antidepressive Agents, Tricyclic; Critical Care; | 1997 |
Chronic administration of NMDA glycine partial agonists induces tolerance in the Porsolt swim test.
Topics: Animals; Antidepressive Agents, Tricyclic; Antimetabolites; Cycloserine; Depression; Dose-Response R | 1997 |
Are Wistar-Kyoto rats a genetic animal model of depression resistant to antidepressants?
Topics: Animals; Antidepressive Agents, Tricyclic; Depression; Drug Resistance; Eating; Imipramine; Male; Mo | 1997 |
High affinity [3H]imipramine and [3H]paroxetine binding sites in suicide brains.
Topics: Adolescent; Adult; Aged; Binding Sites; Brain; Depression; Female; Humans; Imipramine; Male; Middle | 1997 |
Individual differences in response to imipramine in the mouse tail suspension test.
Topics: Animals; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Behavior, Anima | 1997 |
Elevated levels of erythropoietin in cerebrospinal fluid of depressed patients.
Topics: Antidepressive Agents, Tricyclic; Cerebrovascular Disorders; Depression; Erythropoietin; Female; Hum | 1998 |
[Putative contribution of the epiphyseal-adrenocortical system in the antidepressive effect of imipramine].
Topics: Adrenal Cortex; Animals; Antidepressive Agents, Tricyclic; Corticosterone; Depression; Drug Interact | 1998 |
An investigation of the antidepressant properties of lofepramine and its desmethylated metabolites in the forced swim and olfactory bulbectomized rat models of depression.
Topics: Animals; Antidepressive Agents, Tricyclic; Depression; Desipramine; Dose-Response Relationship, Drug | 1999 |
Pharmacoeconomic issues in the treatment of depression.
Topics: Algorithms; Antidepressive Agents; Cost of Illness; Cost-Benefit Analysis; Depression; Drug Costs; H | 1995 |
Depressive state with anxiety in repeated cold-stressed mice in forced swimming tests.
Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Behavior, Animal; Cold Temperature; De | 1999 |
Alnespirone (S 20499), an agonist of 5-HT1A receptors, and imipramine have similar activity in a chronic mild stress model of depression.
Topics: Adrenergic Uptake Inhibitors; Animals; Chronic Disease; Depression; Dose-Response Relationship, Drug | 1999 |
Negative affect and voluntary alcohol consumption in Wistar-Kyoto (WKY) and Sprague-Dawley rats.
Topics: Alcoholism; Analysis of Variance; Animals; Antidepressive Agents, Tricyclic; Central Nervous System | 1999 |
Comparison of hypericum extracts with imipramine and fluoxetine in animal models of depression and alcoholism.
Topics: Alcoholism; Animals; Antidepressive Agents; Depression; Drug Evaluation, Preclinical; Female; Fluoxe | 1999 |
A boost for St. John's Wort?
Topics: Antidepressive Agents, Tricyclic; Depression; Drug Interactions; Humans; Hypericum; Imipramine; Phyt | 2000 |
Heinz Lehmann introduces imipramine.
Topics: Antidepressive Agents; Depression; History, 20th Century; Imipramine | 2000 |
Antidepressant-like activity of amisulpride in two animal models of depression.
Topics: Amisulpride; Animals; Antidepressive Agents; Antipsychotic Agents; Depression; Disease Models, Anima | 2000 |
Use of hypericum as antidepressant. Valid measure of antidepressant efficacy in primary care is needed.
Topics: Antidepressive Agents, Tricyclic; Depression; Humans; Hypericum; Imipramine; Phytotherapy; Placebos; | 2000 |
Interaction between N-methyl-D-aspartate receptor antagonists and imipramine in shock-induced depression.
Topics: Animals; Antidepressive Agents, Tricyclic; Depression; Disease Models, Animal; Electroshock; Female; | 1999 |
Antidepressant activity of Indian Hypericum perforatum Linn in rodents.
Topics: Animals; Antidepressive Agents; Depression; Disease Models, Animal; Female; Hypericum; Imipramine; M | 1999 |
The selective sigma2 ligand Lu 28-179 has an antidepressant-like profile in the rat chronic mild stress model of depression.
Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricy | 2000 |
TCAs or SSRIs as initial therapy for depression?
Topics: Adult; Antidepressive Agents, Tricyclic; Costs and Cost Analysis; Depression; Depressive Disorder; D | 1999 |
The NK1-receptor antagonist NKP608 has an antidepressant-like effect in the chronic mild stress model of depression in rats.
Topics: Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Chronic Disease; Depression; Elect | 2000 |
Antidepressant-like effects of the subtype-selective nicotinic acetylcholine receptor agonist, SIB-1508Y, in the learned helplessness rat model of depression.
Topics: Animals; Antidepressive Agents; Avoidance Learning; Depression; Dose-Response Relationship, Drug; Im | 2000 |
Induction of cysteine string protein after chronic antidepressant treatment in rat frontal cortex.
Topics: Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Depression; DNA, Complementary; Fr | 2001 |
Animal models for the study of antidepressant activity.
Topics: Animals; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tri | 2001 |
Expression of the cAMP response element binding protein (CREB) in hippocampus produces an antidepressant effect.
Topics: Animals; Antidepressive Agents; CREB-Binding Protein; Cyclic AMP; Dentate Gyrus; Depression; Genes, | 2001 |
Bayesian model selection: analysis of a survival model with a surviving fraction.
Topics: Algorithms; Antidepressive Agents, Tricyclic; Bayes Theorem; Computer Simulation; Depression; Diseas | 2001 |
The alpha(2a)-adrenergic receptor plays a protective role in mouse behavioral models of depression and anxiety.
Topics: Adrenergic Uptake Inhibitors; Animals; Anxiety; Behavior, Animal; Darkness; Depression; Disease Mode | 2001 |
Antidepressant-like properties of zinc in rodent forced swim test.
Topics: Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Brain; Depression; Dose-Response R | 2001 |
Characteristics of depressive behavior induced by feeding thiamine-deficient diet in mice.
Topics: Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Body Weight; Depression; Diet; Disease | 2001 |
Chronic imipramine treatment partially reverses the long-term changes of hippocampal synaptic plasticity in socially stressed rats.
Topics: Animals; Antidepressive Agents, Tricyclic; Depression; Excitatory Postsynaptic Potentials; Hippocamp | 2001 |
A study of the antidepressant activity of Hypericum perforatum on animal models.
Topics: Animals; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tri | 2001 |
Antidepressant-like action of AGN 2979, a tryptophan hydroxylase activation inhibitor, in a chronic mild stress model of depression in rats.
Topics: Animals; Antidepressive Agents, Tricyclic; Body Weight; Depression; Enzyme Inhibitors; Imipramine; M | 2001 |
Availability of learned helplessness test as a model of depression compared to a forced swimming test in rats.
Topics: Amoxapine; Animals; Antidepressive Agents; Behavior, Animal; Clomipramine; Depression; Disease Model | 2001 |
Chronic treatment with imipramine or mirtazapine antagonizes stress- and FG7142-induced increase in cortical norepinephrine output in freely moving rats.
Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Anxiety; Carbolines; Cerebral Cortex | 2002 |
The reductions in sweetened milk intake induced by interleukin-1 and endotoxin are not prevented by chronic antidepressant treatment.
Topics: Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents; Appetite; Body Weight; Brain; Cyclohex | 2001 |
S-adenosyl-L-methionine prevents 5-HT(1A) receptors up-regulation induced by acute imipramine in the frontal cortex of the rat.
Topics: Animals; Antidepressive Agents, Tricyclic; Depression; Drug Interactions; Frontal Lobe; Imipramine; | 2002 |
Effects of different frequencies of transcranial magnetic stimulation (TMS) on the forced swim test model of depression in rats.
Topics: Animals; Arousal; Depression; Electromagnetic Fields; Helplessness, Learned; Imipramine; Male; Motiv | 2002 |
Agmatine produces antidepressant-like effects in two models of depression in mice.
Topics: Agmatine; Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Depression; Disease Mode | 2002 |
Anxiolytic- and antidepressant-like effects of the non-peptide vasopressin V1b receptor antagonist, SSR149415, suggest an innovative approach for the treatment of stress-related disorders.
Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antid | 2002 |
A random-effects mixture model for classifying treatment response in longitudinal clinical trials.
Topics: Algorithms; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Clinical Trials as Topic; Depres | 2001 |
Antidepressant activity of standardized extract of Bacopa monniera in experimental models of depression in rats.
Topics: Administration, Oral; Animals; Antidepressive Agents; Bacopa; Behavior, Animal; Depression; Disease | 2002 |
Proceedings: Methylamphetamine withdrawal as a model for the depressive state: antagonism of post-amphetamine depression by imipramine.
Topics: Animals; Brain Chemistry; Depression; Disease Models, Animal; Humans; Imipramine; Male; Methamphetam | 1975 |
Tardive dyskinesia: relationship with a primary affective disorder.
Topics: Adult; Affective Symptoms; Aged; Alcoholism; Amitriptyline; Antipsychotic Agents; Chlordiazepoxide; | 1977 |
Systems in stress.
Topics: Adolescent; Adult; Depression; Family Therapy; Female; Hospitalization; Humans; Imipramine; Interper | 1977 |
The neuropharmacology of depression.
Topics: Amitriptyline; Brain; Brain Chemistry; Depression; Desipramine; Dopamine; Humans; Imipramine; Models | 1977 |
[Tests on the vegetative dynamics of depression under thymoleptic treatment].
Topics: Adult; Blood Pressure; Depression; Dibenzazepines; Female; Heart Rate; Hemodynamics; Humans; Imipram | 1975 |
Delusional unipolar depression: description and drug response.
Topics: Adult; Aged; Amitriptyline; Antidepressive Agents; Antipsychotic Agents; Delusions; Depression; Fema | 1978 |
The effect of unilateral amygdala lesion on the imipramine action in behavioural despair in rats.
Topics: Amygdala; Animals; Behavior, Animal; Depression; Humans; Imipramine; Male; Motor Activity; Rats | 1979 |
Encouraging compliance with antidepressant therapy.
Topics: Amitriptyline; Depression; Drug Therapy, Combination; Humans; Imipramine; Patient Compliance | 1977 |
Clinical characteristics of imipramine-induced orthostatic hypotension.
Topics: Adult; Aged; Blood Pressure; Depression; Female; Humans; Hypotension, Orthostatic; Imipramine; Male; | 1979 |
Effects of imipramine treatment of separation-induced social disorders in rhesus monkeys.
Topics: Animals; Depression; Disease Models, Animal; Exploratory Behavior; Female; Haplorhini; Humans; Imipr | 1978 |
Exploration of affective illness.
Topics: Adult; Bipolar Disorder; Brain; Depression; Dose-Response Relationship, Drug; Drug Therapy, Combinat | 1976 |
The role of the psychiatric consultant in the treatment of burned patients.
Topics: Adult; Affective Symptoms; Aftercare; Attitude of Health Personnel; Burns; Delirium; Depression; Fem | 1975 |
Cyclic AMP in cerebrospinal fluid of manic and depressive patients.
Topics: Administration, Oral; Amitriptyline; Bipolar Disorder; Cyclic AMP; Depression; Humans; Imipramine; L | 1977 |
Behavioural despair in rats: a new model sensitive to antidepressant treatments.
Topics: Animals; Antidepressive Agents; Depression; Disease Models, Animal; Electroshock; Humans; Imipramine | 1978 |
Imipramine and EEG sleep in children with depressive symptoms.
Topics: Adolescent; Child; Depression; Electroencephalography; Female; Humans; Imipramine; Male; Sleep; Slee | 1979 |
EEG features of depressive and schizophrenic states.
Topics: Adult; Alpha Rhythm; Antipsychotic Agents; Brain; Depression; Diagnosis, Differential; Electroenceph | 1975 |
The use of psychoactive drugs in the long-term treatment of chronic alcoholics.
Topics: Alcoholism; Anti-Anxiety Agents; Antipsychotic Agents; Anxiety; Chlordiazepoxide; Chlorpromazine; Ch | 1975 |
At the research front: cognitive therapy for depression.
Topics: Adjustment Disorders; Cognition; Depression; Humans; Imipramine; Psychotherapy; Psychotherapy, Group | 1979 |
Imipramine and children: a review and some speculations about the mechanism of drug action.
Topics: Adolescent; Age Factors; Child; Child, Preschool; Depression; Dopamine; Enuresis; Epilepsy, Absence; | 1977 |
Impotence responsive to glyceryl trinitrate.
Topics: Angina Pectoris; Arteriosclerosis; Depression; Erectile Dysfunction; Humans; Imipramine; Male; Middl | 1977 |
Rapid-cycling affective disorders during imipramine treatment: a case report.
Topics: Adult; Bipolar Disorder; Depression; Female; Humans; Imipramine; Periodicity; Pregnancy; Puerperal D | 1979 |
"Hypohypomania" and tricyclic antidepressant choice.
Topics: Amitriptyline; Depression; Humans; Imipramine; Impulsive Behavior; Interview, Psychological | 1979 |
Imipramine and delusional depressions.
Topics: Delusions; Depression; Humans; Imipramine; Middle Aged | 1979 |
Depression treated with imipramine and ECT: the DeCarolis study reconsidered.
Topics: Adjustment Disorders; Affective Disorders, Psychotic; Bipolar Disorder; Delusions; Depression; Dose- | 1979 |
Predicting imipramine response.
Topics: Delusions; Depression; Humans; Imipramine | 1979 |
Prediction of steady-state imipramine and desmethylimipramine plasma concentrations from single-dose data.
Topics: Depression; Desipramine; Drug Administration Schedule; Female; Humans; Imipramine; Kinetics; Male; M | 1979 |
Monitoring tricyclic antidepressant plasma concentrations.
Topics: Amitriptyline; Antidepressive Agents; Antidepressive Agents, Tricyclic; Depression; Humans; Imiprami | 1979 |
Family practice management of depression: how to select tricyclic antidepressants.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Depression; Doxepin; Family Practice; Humans; Imipr | 1979 |
Effects of triiodothyronine on drug levels and cardiac function in depressed patients treated with imipramine.
Topics: Adult; Depression; Desipramine; Female; Heart Conduction System; Heart Rate; Humans; Imipramine; Mid | 1979 |
Rapid opiate detoxification: clinical evidence of antidepressant and antipanic effects of opiates.
Topics: Adult; Anxiety; Clonidine; Depression; Drug Therapy, Combination; Fear; Humans; Imipramine; Male; Me | 1979 |
[Effects of antidepressants (amoxapine and imipramine) on serum anterior pituitary hormone levels in patients with depressive states (author's transl)].
Topics: Adolescent; Adult; Amoxapine; Child; Depression; Dibenzoxazepines; Female; Humans; Imipramine; Male; | 1979 |
Response to sleep deprivation as a predictor of therapeutic results with antidepressant drugs.
Topics: Antidepressive Agents, Tricyclic; Clomipramine; Depression; Female; Humans; Imipramine; Male; Maprot | 1979 |
Novel antidepressants and the biogenic amine hypothesis of depression. The case for iprindole and mianserin.
Topics: Adjustment Disorders; Affective Disorders, Psychotic; Amitriptyline; Biogenic Amines; Brain; Depress | 1979 |
Nomifensine: A review of its pharmacological properties and therapeutic efficacy in depressive illness.
Topics: Animals; Biogenic Amines; Brain; Depression; Epilepsy; Evaluation Studies as Topic; Humans; Imiprami | 1979 |
Urinary 3-methoxy-4-hydroxyphenylglycol (MHPG) excretion in depression.
Topics: Adult; Bipolar Disorder; Depression; Electroconvulsive Therapy; Female; Glycols; Humans; Imipramine; | 1979 |
Drugs and depression--tools and treatments.
Topics: Antidepressive Agents; Antidepressive Agents, Tricyclic; Depression; Humans; Imipramine; Monoamine O | 1979 |
Guidelines for clinical use in interpreting tricyclic plasma levels.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Depression; Dose-Response Relationship, Drug; Human | 1979 |
The electrocardiographic and antiarrhythmic effects of imipramine hydrochloride at therapeutic plasma concentrations.
Topics: Adult; Aged; Anti-Arrhythmia Agents; Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Bundle- | 1979 |
The relationship of imipramine plasma levels and verbalized hostility in nondelusional endogenous depressives.
Topics: Adult; Aged; Depression; Dose-Response Relationship, Drug; Female; Hostility; Humans; Imipramine; Ma | 1979 |
Effects of imipramine on aggression and dejection in depressed children.
Topics: Aggression; Anger; Child; Depression; Dose-Response Relationship, Drug; Hostility; Humans; Imipramin | 1979 |
Cortisol hypersecretion in prepubertal depressive illness: a preliminary report.
Topics: Child; Circadian Rhythm; Depression; Female; Humans; Hydrocortisone; Imipramine; Male | 1979 |
Trazodone in depressions.
Topics: Depression; Double-Blind Method; Humans; Imipramine; Piperazines; Trazodone | 1979 |
Factors influencing clinical response to psychotropic drugs. Imipramine in depression.
Topics: Biological Availability; Culture; Depression; Female; Humans; Imipramine; Male; Patient Compliance; | 1979 |
Plasma levels of imipramine (IMI) and desmethylimipramine (DMI) and clinical response in prepubertal major depressive disorder: a preliminary report.
Topics: Child; Depression; Desipramine; Female; Humans; Imipramine; Male | 1979 |
Guidelines for therapeutic monitoring of tricyclic antidepressant plasma levels.
Topics: Age Factors; Amitriptyline; Antidepressive Agents, Tricyclic; Depression; Desipramine; Drug Interact | 1979 |
"Behavioural despair" in rats and mice: strain differences and the effects of imipramine.
Topics: Animals; Behavior, Animal; Depression; Humans; Imipramine; Male; Mice; Motor Activity; Rats; Species | 1978 |
Clinical utility of tricyclic antidepressant blood levels: a case report.
Topics: Aged; Aging; Depression; Desipramine; Drug Therapy, Combination; Female; Humans; Imipramine; Phenoth | 1979 |
A reward-reduction model of depression using self stimulating rats: an appraisal.
Topics: Amphetamine; Animals; Depression; Disease Models, Animal; Humans; Imipramine; Male; Protriptyline; R | 1979 |
[Diagnosis and treatment of latent depression].
Topics: Adult; Amitriptyline; Antidepressive Agents; Depression; Female; Humans; Imipramine; Male; Middle Ag | 1979 |
Non-specificity of "behavioral despair" as an animal model of depression.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Depression; Disease Models, Animal; Female; Humans | 1979 |
Reversal of learned helplessness by imipramine.
Topics: Animals; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Escape Reaction; Huma | 1979 |
The kinetics of imipramine-N-oxide in man.
Topics: Administration, Oral; Adult; Biological Availability; Depression; Desipramine; Drug Evaluation; Fema | 1978 |
Rampant dental caries in the treatment of depression.
Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Dental Caries; Depression; Drug Combinations | 1978 |
Plasma levels of tricyclic antidepressants and clinical efficacy: review of the literature -- part II.
Topics: Antidepressive Agents, Tricyclic; Biotransformation; Clomipramine; Depression; Desipramine; Dibenzoc | 1979 |
The electroencephalographic and psychological effects of imipramine in depressed inpatients.
Topics: Adult; Depression; Desipramine; Electroencephalography; Female; Humans; Imipramine; Male; Middle Age | 1977 |
The physician's knowledge of psychotropic drugs: preliminary results.
Topics: Amitriptyline; Anxiety; Clinical Competence; Depression; Diazepam; Humans; Imipramine; Internal Medi | 1978 |
Effects of imipramine on chromosomes in psychiatric patients.
Topics: Adult; Age Factors; Aged; Aneuploidy; Chromosome Aberrations; Depression; Female; Humans; Imipramine | 1978 |
Agranulocytosis associated with tricyclics.
Topics: Adult; Agranulocytosis; Depression; Female; Humans; Imipramine | 1978 |
The cardiac effects of therapeutic plasma concentrations of imipramine.
Topics: Adult; Aged; Depression; Electrocardiography; Heart; Heart Conduction System; Humans; Hypotension, O | 1978 |
Speech blockage: a tricyclic side effect.
Topics: Adult; Amitriptyline; Depression; Dose-Response Relationship, Drug; Female; Humans; Imipramine; Male | 1978 |
The myth of pseudodementia: depression and the aging brain.
Topics: Aged; Dementia; Depression; Diagnosis, Differential; Humans; Imipramine; Male | 1978 |
Platelet MAO inhibition following tricyclic antidepressant therapy.
Topics: Adult; Amitriptyline; Blood Platelets; Depression; Dose-Response Relationship, Drug; Female; Humans; | 1978 |
Protracted vomiting following abrupt cessation of psychotropics: a case report.
Topics: Adult; Benztropine; Depression; Drug Therapy, Combination; Haloperidol; Humans; Imipramine; Male; Sc | 1978 |
A pilot open trial of imipramine in prepubertal depressive illness [proceedings].
Topics: Child; Depression; Female; Humans; Imipramine; Male; Pilot Projects | 1978 |
Clinical correlates of tricyclic antidepressant-mediated inhibition of platelet monoamine oxidase.
Topics: Adult; Amitriptyline; Blood Platelets; Depression; Depression, Chemical; Humans; Imipramine; Male; M | 1978 |
Toxoplasmosis masquerading as a psychotropic side effect.
Topics: Antidepressive Agents, Tricyclic; Depression; Diagnosis, Differential; Female; Humans; Imipramine; M | 1978 |
Imipramine and desipramine plasma levels: relationship to dosage schedule and sampling time.
Topics: Adult; Blood Specimen Collection; Depression; Desipramine; Drug Administration Schedule; Female; Hal | 1978 |
Speech blockage in young patients taking tricyclics.
Topics: Adult; Age Factors; Amitriptyline; Depression; Humans; Imipramine; Male; Speech Disorders | 1978 |
The role antidepressants in hospitalised cancer patients. (A pilot study).
Topics: Adult; Depression; Female; Humans; Imipramine; Male; Middle Aged; Neoplasms | 1978 |
Studies on plasma level/effect relationships in imipramine therapy.
Topics: Depression; Desipramine; Humans; Imipramine; Kinetics; Methods | 1978 |
Iatrogenic cataract.
Topics: Adult; Cataract; Depression; Female; Humans; Iatrogenic Disease; Imipramine | 1978 |
[Blood levels of tricyclics and evolution of depressive syndrome during therapy].
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Depression; Humans; Imipramine; Nortriptyline | 1978 |
Prepubertal major depressive disorder: a pilot study.
Topics: Child; Child Behavior Disorders; Depression; Female; Humans; Imipramine; Male; Pilot Projects; Puber | 1978 |
[Somatic disorders and depressive states].
Topics: Amitriptyline; Antidepressive Agents; Cardiovascular Diseases; Depression; Disease; Drug Hypersensit | 1978 |
Depression in the elderly.
Topics: Aged; Antidepressive Agents; Depression; Diagnosis, Differential; Electroconvulsive Therapy; Environ | 1979 |
Hypnopompic hallucinations and treatment with imipramine.
Topics: Depression; Dose-Response Relationship, Drug; Female; Hallucinations; Humans; Imipramine; Middle Age | 1979 |
Myxedematous madness without myxedema. Selective defect of TSH release on TRF loading in a young woman with a history of severe depressive illness cured with thryoid hormone replacement therapy.
Topics: Adolescent; Adult; Depression; Female; Humans; Hypopituitarism; Imipramine; Iodine; Pituitary Gland; | 1976 |
[A case of myocardiopathy with hypothiaminemia exacerbated by imiparmine].
Topics: Cardiomyopathies; Depression; Electrocardiography; Female; Humans; Imipramine; Middle Aged; Thiamine | 1976 |
[Imipramine in the therapy of schizophrenic psychoses].
Topics: Adult; Autistic Disorder; Bipolar Disorder; Depression; Dose-Response Relationship, Drug; Drug Thera | 1975 |
In vivo inhibition of platelet MAO activity by tricyclic antidepressants.
Topics: Adult; Amitriptyline; Blood Platelets; Depression; Humans; Imipramine; Male; Middle Aged; Monoamine | 1977 |
Imipramine and depression.
Topics: Depression; Humans; Imipramine | 1977 |
Clinical implications of imipramine plasma levels for depressive illness.
Topics: Bipolar Disorder; Delusions; Depression; Desipramine; Dose-Response Relationship, Drug; Female; Huma | 1977 |
The unremembered, unimproved depressed patient.
Topics: Adjustment Disorders; Affective Disorders, Psychotic; Amitriptyline; Depression; Electroshock; Human | 1977 |
[Recurrent ventricular fibrillation in a patient treated with imipramine].
Topics: Depression; Female; Humans; Imipramine; Middle Aged; Recurrence; Ventricular Fibrillation | 1977 |
Relationship between age and tricyclic antidepressant plasma levels.
Topics: Administration, Oral; Adult; Age Factors; Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Bod | 1977 |
Depression in children referred to an educational diagnostic center: diagnosis and treatment and analysis of criteria and literature review.
Topics: Age Factors; Amitriptyline; Child; Depression; Female; Humans; Imipramine; Intelligence Tests; Male; | 1977 |
Successful treatment of anorexia nervosa with imipramine.
Topics: Adolescent; Anorexia Nervosa; Depression; Female; Humans; Imipramine; Male; Sleep Initiation and Mai | 1977 |
Interaction between phenytoin and imipramine.
Topics: Adult; Depression; Drug Interactions; Epilepsy; Humans; Imipramine; Phenytoin; Time Factors | 1977 |
IQ as a predictor of antidepressant responses to imipramine.
Topics: Depression; Female; Humans; Imipramine; Intelligence; Male | 1977 |
An examination of baseline and drug-induced levels of cyclic nucleotides in the cerebrospinal fluid of control and psychiatric patients.
Topics: Adolescent; Adult; Aged; Amitriptyline; Bipolar Disorder; Depression; Humans; Imipramine; Lithium; M | 1976 |
Red blood cell catechol O-methyl transferase and response to imipramine in unipolar depressive women.
Topics: Adult; Aged; Catechol O-Methyltransferase; Depression; Erythrocytes; Female; Humans; Imipramine; Mid | 1976 |
Combining tricyclic and monoamine oxidase inhibitor antidepressants.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Depression; Drug Therapy, Combination; Humans; Hype | 1976 |
Investigation of the orthostatic reaction after intravenous administration of imipramine, chlorimipramine, and inimpramine-N-oxide.
Topics: Adult; Aged; Blood Pressure; Clomipramine; Depression; Dibenzazepines; Dose-Response Relationship, D | 1976 |
Effect of flupenthixol on depression with special reference to combination use with tricyclic antidepressants. An uncontrolled pilot study with 45 patients.
Topics: Adolescent; Adult; Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Child; Clomipramine; Depre | 1976 |
Correlation between plasma and cerebrospinal levels of imipramine.
Topics: Depression; Desipramine; Humans; Imipramine | 1976 |
Sensitivity of rating scales completed by psychiatrists, nurses and patients to antidepressant drug effects.
Topics: Adult; Antidepressive Agents; Chlorpromazine; Depression; Diazepam; Emotions; Female; Humans; Imipra | 1976 |
[Psychotropic drugs and glaucoma (author's transl)].
Topics: Adult; Aged; Clomipramine; Depression; Desipramine; Dibenzocycloheptenes; Female; Fluphenazine; Glau | 1976 |
Plasma levels of imipramine in depression. Environmental and genetic factors.
Topics: Adult; Binding Sites; Biological Availability; Depression; Desipramine; Humans; Hydroxylation; Imipr | 1976 |
Atypical endogenous depression. Diagnostic criteria.
Topics: Adult; Amitriptyline; Depression; Doxepin; Family; Female; Humans; Imipramine; Interpersonal Relatio | 1976 |
Psyche and rheuma.
Topics: Aged; Attitude; Child; Chronic Disease; Depression; Family; Female; Humans; Imipramine; Male; Pain; | 1976 |
Antidepressant drugs.
Topics: Age Factors; Amitriptyline; Antidepressive Agents; Anxiety; Arrhythmias, Cardiac; Bipolar Disorder; | 1975 |
Patterns of symptom change in anxious depressed outpatients treated with different drugs.
Topics: Amitriptyline; Antidepressive Agents; Anxiety; Chlordiazepoxide; Chlorpromazine; Depression; Desipra | 1975 |
Managing depression in the '70s.
Topics: Adjustment Disorders; Antidepressive Agents; Bipolar Disorder; Depression; Drug Therapy, Combination | 1975 |
Cardiac effects of imipramine hydrochloride in the elderly.
Topics: Aged; Depression; Electrocardiography; Heart; Humans; Imipramine | 1975 |
Reduced central serotonergic activity in mania: implications for the relationship between depression and mania.
Topics: Bipolar Disorder; Brain; Depression; Disease Models, Animal; Humans; Hydroxyindoleacetic Acid; Hypno | 1975 |
Psychological medicine. Management of depression.
Topics: Amitriptyline; Antidepressive Agents; Anxiety; Clomipramine; Depression; Drug Interactions; Electroc | 1975 |
Gas chromatographic-mass fragmentographic determation of "steady-state" plasma levels of imipramine and desipramine in chronically treated patients.
Topics: Chromatography, Gas; Depression; Desipramine; Dose-Response Relationship, Drug; Female; Gas Chromato | 1975 |
Fifteenth Emil A. Gutheil Memorial Conference. The range of therapies in the treatment of severely depressed suicidal patients.
Topics: Ambulatory Care; Antidepressive Agents; Bipolar Disorder; Crisis Intervention; Depression; Electroco | 1975 |
Imipramine-induced heart block. A longitudinal case study.
Topics: Administration, Oral; Aged; Bundle-Branch Block; Depression; Electrocardiography; Heart Conduction S | 1975 |
Plasma levels of imipramine and clinical outcome.
Topics: Depression; Humans; Imipramine | 1975 |
Biogenic amines and depression. Biochemical and pharmacological separation of two types of depression.
Topics: Amitriptyline; Biogenic Amines; Depression; Desipramine; Dextroamphetamine; Humans; Hydroxyindoleace | 1975 |
Influence of imipramine on the circulatory system in the course of endogenous depressive syndromes. II. Influence of imipramine on vascular reflexes.
Topics: Adult; Blood Pressure; Cold Temperature; Depression; Heart Rate; Hemodynamics; Humans; Imipramine; M | 1975 |
[Methodology of therapeutic trials in psychopharmacology (author's transl)].
Topics: Depression; Diagnosis, Differential; Female; Humans; Imipramine; Male; Social Class; Terminology as | 1975 |
Cerebrospinal fluid amine metabolites in affective illness and schizophrenia: clinical and pharmacological studies.
Topics: Affective Symptoms; Amines; Depression; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Imipram | 1975 |
[Limits of efficacy and tolerance of antidepressive medications].
Topics: Adjustment Disorders; Antidepressive Agents, Tricyclic; Bipolar Disorder; Depression; Humans; Imipra | 1975 |
Memory functions in depression.
Topics: Amitriptyline; Depression; Female; Humans; Imipramine; Male; Memory Disorders; Memory, Short-Term | 1976 |
Letter: Controlled trials of imipramine.
Topics: Depression; Drug Evaluation; Humans; Imipramine | 1976 |
Drug and psychotherapy interactions in depression.
Topics: Anxiety; Attitude; Depression; Diazepam; Drug Therapy, Combination; Employment; Estrogens; Female; H | 1976 |
Platelet 3H-imipramine uptake receptor density and serum serotonin levels in patients with fibromyalgia/fibrositis syndrome.
Topics: Blood Platelets; Carrier Proteins; Depression; Fibromyalgia; Humans; Imipramine; Monoamine Oxidase; | 1992 |
[Experimental model of depression: neurochemical changes and the effects of imipramine and citalopram].
Topics: Animals; Antidepressive Agents; Brain; Catecholamines; Citalopram; Depression; Disease Models, Anima | 1992 |
[Treatment of patients with panic disorder and an elevated urinary excretion of MHPG using imipramine or clonazepam].
Topics: Adult; Anxiety Disorders; Clonazepam; Depression; Female; Humans; Imipramine; Lactates; Lactic Acid; | 1992 |
Biochemical clues to a fibromyalgia-depression link: imipramine binding in patients with fibromyalgia or depression and in healthy controls.
Topics: Adult; Aged; Analysis of Variance; Depression; Female; Fibromyalgia; Humans; Imipramine; Male; Middl | 1992 |
Chronic variable stress facilitates tumoral growth: reversal by imipramine administration.
Topics: Animals; Cyclosporine; Depression; Disease Models, Animal; Imipramine; Immune Tolerance; Immunity; M | 1992 |
Immobility-reducing effects of antidepressants in a genetic animal model of depression.
Topics: Animals; Antidepressive Agents; Depression; Depression, Chemical; Desipramine; Disease Models, Anima | 1992 |
Effects of MK-801 and antidepressant drugs in the forced swimming test in rats.
Topics: Animals; Antidepressive Agents; Citalopram; Depression; Dizocilpine Maleate; Haloperidol; Imipramine | 1992 |
Platelet [3H]imipramine binding in migraine and tension headache in relation to depression.
Topics: Adult; Anxiety; Blood Platelets; Carrier Proteins; Depression; Female; Headache; Humans; Imipramine; | 1991 |
Tritiated imipramine binding. A peripheral marker for serotonin in Parkinson's disease.
Topics: Aged; Biomarkers; Blood Platelets; Depression; Humans; Hydroxyindoleacetic Acid; Imipramine; Middle | 1991 |
Early individualization of tricyclic antidepressant dosing using a Bayesian pharmacokinetic model.
Topics: Adult; Antidepressive Agents, Tricyclic; Bayes Theorem; Depression; Female; Humans; Imipramine; Male | 1991 |
Circadian variation in platelet imipramine binding during the day in healthy subjects.
Topics: Adult; Biomarkers; Blood Platelets; Circadian Rhythm; Depression; Female; Humans; Imipramine; In Vit | 1991 |
Influence of gonadotropin-releasing hormone on castration-induced 'depression' in mice: a behavioral and binding study.
Topics: Animals; Behavior, Animal; Carrier Proteins; Castration; Cerebral Cortex; Depression; Female; Gonado | 1990 |
Social model of depression in mice of C57BL/6J strain.
Topics: Aggression; Animals; Depression; Disease Models, Animal; Exploratory Behavior; Gastric Mucosa; Gastr | 1991 |
Lack of tolerance to imipramine or mianserine in two animal models of depression.
Topics: Amphetamine; Animals; Anorexia; Behavior, Animal; Depression; Disease Models, Animal; Dose-Response | 1990 |
Effect of imipramine in the "learned helplessness" model of depression in rats is not mimicked by combinations of specific reuptake inhibitors and scopolamine.
Topics: Animals; Antidepressive Agents; Avoidance Learning; Behavior, Animal; Citalopram; Depression; Drug S | 1990 |
Imipramine pharmacokinetics in depressed geriatric patients.
Topics: Adult; Age Factors; Aged; Chromatography, High Pressure Liquid; Depression; Desipramine; Female; Hum | 1990 |
MIF-1 is active in a chronic stress animal model of depression.
Topics: Animals; Antidepressive Agents; Depression; Dose-Response Relationship, Drug; Imipramine; Male; MSH | 1989 |
Depression in patients with Alzheimer's disease.
Topics: Aged; Alzheimer Disease; Depression; Humans; Imipramine | 1989 |
Imipramine for patients with Alzheimer's disease with and without depression.
Topics: Alzheimer Disease; Depression; Humans; Imipramine | 1989 |
Perception of appetite and weight change during treatment for depression.
Topics: Adult; Appetite; Body Image; Depression; Feeding Behavior; Female; Humans; Imipramine; Male; Middle | 1989 |
Role of central histaminergic mechanism in behavioural depression (swimming despair) in mice.
Topics: Animals; Atropine; Central Nervous System; Cimetidine; Depression; Desipramine; Disease Models, Anim | 1988 |
Tritiated imipramine binding distinguishes among subtypes of depression.
Topics: Adult; Ambulatory Care; Bipolar Disorder; Blood Platelets; Carrier Proteins; Cell Membrane; Depressi | 1985 |
Platelet radioligand binding and neuroendocrine challenge tests in depression.
Topics: Adult; Binding Sites; Blood Platelets; Blood Pressure; Clonidine; Depression; Female; Growth Hormone | 1986 |
Effect of nifedipine on the shuttlebox escape deficit induced by inescapable shock in the rat.
Topics: Animals; Binding Sites; Brain; Depression; Electroshock; Escape Reaction; Imipramine; Kinetics; Male | 1988 |
[A case of dynamic ileus caused by tricyclic antidepressive agents].
Topics: Antidepressive Agents, Tricyclic; Depression; Desipramine; Drug Therapy, Combination; Female; Humans | 1988 |
Neutropenia with cross-intolerance between two tricyclic antidepressant agents.
Topics: Adult; Agranulocytosis; Cross Reactions; Depression; Female; Humans; Imipramine; Neutropenia; Nortri | 1987 |
Binding of imipramine to platelet membranes is lower in alcoholics than in controls.
Topics: Adult; Aged; Alcoholism; Blood Platelets; Depression; Humans; Imipramine; Male; Membranes; Middle Ag | 1987 |
Oxytocin acts as an antidepressant in two animal models of depression.
Topics: Animals; Depression; Disease Models, Animal; Drug Interactions; Escape Reaction; Female; Imipramine; | 1987 |
Animal model of depression: retention of motor depression not predictable from the threshold of reaction to the inescapable shock.
Topics: Animals; Bromocriptine; Depression; Differential Threshold; Disease Models, Animal; Electroshock; Es | 1987 |
Pharmacologic profile of fezolamine fumarate: a nontricyclic antidepressant in animal models.
Topics: Animals; Antidepressive Agents; Biological Transport; Blepharoptosis; Brain; Depression; Disease Mod | 1987 |
Noradrenergic rather than GABAergic processes as the common mediation of the antidepressant profile of GABA agonists and imipramine-like drugs in animals.
Topics: Animals; Antidepressive Agents; Brain; Depression; Disease Models, Animal; gamma-Aminobutyric Acid; | 1987 |
Targeting imipramine dose in children with depression.
Topics: Absorption; Administration, Oral; Child; Depression; Desipramine; Female; Half-Life; Humans; Imipram | 1986 |
Antidepressants: their uses in nonpsychiatric disorders of aging.
Topics: Affective Symptoms; Aged; Antidepressive Agents; Chronic Disease; Colonic Diseases, Functional; Depr | 1986 |
Profound behavioral toxicity due to tricyclic antidepressants.
Topics: Acute Disease; Adult; Age Factors; Depression; Desipramine; Female; Hospitalization; Humans; Imipram | 1986 |
Cardiovascular effects of polycyclic antidepressants.
Topics: Adult; Amitriptyline; Amoxapine; Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Depression; | 1986 |
Changes in socio-emotional behavior under imipramine treatment in normal and amygdalo-hypothalamic dogs.
Topics: Amygdala; Animals; Depression; Disease Models, Animal; Dogs; Emotions; Hypothalamic Area, Lateral; I | 1986 |
Antidepressant-binding sites in brain and platelets.
Topics: Animals; Antidepressive Agents; Binding, Competitive; Blood Platelets; Brain; Carrier Proteins; Cell | 1986 |
Lithium potentiation of imipramine in treatment resistant depression.
Topics: Adult; Depression; Drug Synergism; Female; Humans; Imipramine; Lithium; Lithium Carbonate; Male; Mid | 1985 |
Antidepressant-resistant depression in the elderly.
Topics: Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Combined Modality Therapy; Depression; Drug R | 1986 |
Tricyclic antidepressant and metabolite levels in chronic renal failure.
Topics: Adult; Aged; Amitriptyline; Antidepressive Agents; Chromatography, Liquid; Depression; Desipramine; | 1985 |
Imipramine treatment differentially affects platelet 3H-imipramine binding and serotonin uptake in depressed patients.
Topics: Adolescent; Adult; Blood Platelets; Depression; Female; Humans; Imipramine; Kinetics; Male; Middle A | 1985 |
Mania following change from trazodone to imipramine.
Topics: Adult; Bipolar Disorder; Depression; Female; Humans; Imipramine; Middle Aged; Trazodone | 1985 |
Hypnotics and hangovers.
Topics: Antidepressive Agents; Depression; Humans; Hypnotics and Sedatives; Imipramine; Sleep Initiation and | 1971 |
Adverse reactions to the tricyclic-antidepressant drugs. Report from Boston Collaborative Drug Surveillance Program.
Topics: Amitriptyline; Anxiety; Arrhythmias, Cardiac; Cardiovascular Diseases; Depression; Female; Heart; Hu | 1972 |
Pain patterns in the rheumatic disorders.
Topics: Anxiety; Arthritis; Arthritis, Rheumatoid; Aspirin; Chronic Disease; Depression; Giant Cell Arteriti | 1972 |
Renal damage due to imipramine.
Topics: Age Factors; Aged; Depression; Humans; Imipramine; Kidney; Male | 1973 |
Letter: Childhood enuresis-adult depression.
Topics: Adult; Child; Depression; Enuresis; Humans; Imipramine | 1974 |
The choice of alternative antidepressants.
Topics: Adult; Amitriptyline; Antidepressive Agents; Depression; Evaluation Studies as Topic; Female; Humans | 1973 |
Uptake of (3H)5-hydroxytryptamine and (3H)noradrenaline by slices of rat brain incubated in plasma from patients treated with chlorimipramine, imipramine or amitroptyline.
Topics: Amitriptyline; Animals; Brain; Depression; Dibenzazepines; Female; Humans; Imipramine; In Vitro Tech | 1973 |
Psychosis associated with the use of a sequential oral contraceptive.
Topics: Adult; Chlormadinone Acetate; Chlorpromazine; Contraceptives, Oral; Depression; Estrogens; Female; H | 1967 |
Psychotropic--hypnotic drug combination.
Topics: Depression; Diphenhydramine; Drug Synergism; Epistaxis; Humans; Imipramine; Mental Disorders; Methaq | 1967 |
Intensification of the central serotoninergic processes as a possible determinant of the thymoleptic effect.
Topics: Adrenal Cortex Hormones; Animals; Antidepressive Agents; Brain; Brain Chemistry; Depression; Drug Sy | 1969 |
Hypertension during imipramine treatment.
Topics: Depression; Female; Humans; Hypertension; Imipramine; Middle Aged | 1970 |
The switch process from depression to mania: relationship to drugs which alter brain amines.
Topics: Amitriptyline; Behavior; Bipolar Disorder; Brain; Catecholamines; Depression; Dopamine; Electroencep | 1970 |
Mental symptoms in Parkinsonian patients treated with L-dopa.
Topics: Aged; Behavior; Depression; Dihydroxyphenylalanine; Dreams; Female; Humans; Imipramine; Male; Memory | 1970 |
Letter: Pheochromocytoma and tricyclic antidepressants.
Topics: Adrenal Gland Neoplasms; Adult; Blood Vessels; Catecholamines; Depression; Epilepsy, Tonic-Clonic; F | 1974 |
The psychiatrist attitudes and therapeutic means when faced with resistant depressions.
Topics: Amitriptyline; Amphetamine; Antidepressive Agents; Autistic Disorder; Depression; Drug Resistance; D | 1974 |
Clinical application of antidepressant agents in disabled and rehabilitation patients.
Topics: Aged; Amitriptyline; Amphetamine; Antidepressive Agents; Depression; Disabled Persons; Hemiplegia; H | 1965 |
An appraisal of two antidepressants used with the physically debilitated.
Topics: Adult; Depression; Disabled Persons; Female; Hemiplegia; Humans; Imipramine; Indoles; Male; Parapleg | 1966 |
Imipramine and pregnancy.
Topics: Abnormalities, Drug-Induced; Depression; Down Syndrome; Female; Fetal Death; Humans; Imipramine; Pre | 1972 |
The "kynurenine shunt" and depression.
Topics: Adrenal Glands; Adrenalectomy; Amitriptyline; Animals; Antidepressive Agents; Depression; Humans; Im | 1974 |
Brain serotonin, affective illness, and antidepressant drugs: cerebrospinal fluid studies with probenecid.
Topics: Affective Symptoms; Amitriptyline; Antidepressive Agents; Brain; Brain Chemistry; Depression; Fenclo | 1974 |
[True and false adverse effects of thymoanaleptic medications].
Topics: Amitriptyline; Antidepressive Agents; Chemical and Drug Induced Liver Injury; Cholestasis; Depressio | 1968 |
Drug therapy in alcoholism.
Topics: Adult; Alcoholic Intoxication; Alcoholism; Antidepressive Agents; Anxiety; Carbamates; Chlordiazepox | 1970 |
On the treatment of rapid eye movement narcolepsy.
Topics: Adult; Amphetamine; Antidepressive Agents; Cataplexy; Depression; Desipramine; Electroencephalograph | 1974 |
Corticotropin release during ECT in man.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Adult; Anesthesia, General; Barbiturates; Colitis, Ulce | 1974 |
Outpatient group therapy with geriatric patients.
Topics: Aged; Amitriptyline; Antidepressive Agents; Anxiety; Depression; Female; Geriatrics; Humans; Imipram | 1967 |
Norepinephrine metabolism and drugs used in the affective disorders: a possible mechanism of action.
Topics: Animals; Antidepressive Agents; Bipolar Disorder; Brain; Central Nervous System Stimulants; Chlorpro | 1967 |
[On the clinical course and therapy of pathological conditions caused by incompatible antidepressants].
Topics: Adult; Anuria; Bipolar Disorder; Bis-Trimethylammonium Compounds; Depression; Depressive Disorder, M | 1968 |
[Different urinary excretion of 3-methoxy-4-hydroxyphenyl-glycol and response to tricyclic antidepressive drugs].
Topics: Amitriptyline; Depression; Female; Glycols; Humans; Imipramine; Male; Methoxyhydroxyphenylglycol; No | 1974 |
[Self- and foreign placements of current condition in psychopharmacological longitudinal studies].
Topics: Adolescent; Aggression; Alcoholism; Antiparkinson Agents; Anxiety; Depression; Drug Evaluation; Extr | 1974 |
Endogenomorphic depression. A conceptual and terminological revision.
Topics: Adjustment Disorders; Anxiety Disorders; Bipolar Disorder; Depression; Factor Analysis, Statistical; | 1974 |
Confusional states in elderly mental patients treated with antidepressants.
Topics: Aged; Amitriptyline; Cognition Disorders; Confusion; Depression; Drug Therapy, Combination; Female; | 1974 |
The effects of hypnotics on imipramine treatment.
Topics: Adult; Amobarbital; Depression; Desipramine; Drug Interactions; Drug Therapy, Combination; Female; H | 1974 |
Proceedings: Race and response to antidepressant drugs in hospitalized depressed patients.
Topics: Adult; Antidepressive Agents; Black or African American; Chlorpromazine; Depression; Humans; Imipram | 1974 |
Combined thyroid (triiodothyronine)-tricyclic antidepressant treatment in depressive states.
Topics: Adjustment Disorders; Adult; Amitriptyline; Antidepressive Agents; Anxiety; Bipolar Disorder; Blood | 1974 |
Genetic and clinical factors associated with course in depression. Contributions to genetic aspects.
Topics: Alcoholism; Bipolar Disorder; Chlorpromazine; Chronic Disease; Depression; Female; Humans; Imipramin | 1974 |
Contributions to the definition of therapy-resistance and of the therapy-resistant depressions.
Topics: Affective Symptoms; Aged; Depression; Diagnosis, Differential; Drug Resistance; Humans; Imipramine; | 1974 |
Therapy resistant depressions. Methodological problems. Contributions to methodical questions and animal-experimental aspects.
Topics: Antidepressive Agents; Depression; Drug Resistance; Hospitalization; Humans; Imipramine; Lithium; Me | 1974 |
Biochemical criteria for classifying depressive disorders and predicting responses to pharmacotherapy: preliminary findings from studies of norepinephrine metabolism. Contributions to biochemistry.
Topics: Adolescent; Adult; Aged; Amitriptyline; Amphetamine; Anxiety; Bipolar Disorder; Brain; Depression; F | 1974 |
Quantitative determination of imipramine and desmethylimipramine in human plasma by mass fragmentography.
Topics: Chromatography, Gas; Depression; Desipramine; Humans; Imipramine; Mass Spectrometry | 1974 |
The diagnostic process in general practice illustrated by a case of scurvy.
Topics: Aged; Ascorbic Acid; Blood Sedimentation; Depression; Diazepam; Diet; Ecchymosis; Family Practice; F | 1974 |
Predicting treatment responsiveness-resistiveness in a population of depressed patients.
Topics: Antidepressive Agents; Chlorpromazine; Depression; Drug Resistance; Drug Therapy, Combination; Emoti | 1974 |
[Problems of differentiated thymoleptic therapy in phasic depressions].
Topics: Adolescent; Adult; Amitriptyline; Anthracenes; Antidepressive Agents; Azocines; Benzoates; Benzofura | 1974 |
An animal model of depression.
Topics: Acoustic Stimulation; Animals; Behavior, Animal; Conditioning, Classical; Depression; Disease Models | 1974 |
Proceedings: Ptosis as a model of depression.
Topics: Animals; Antidepressive Agents; Blepharoptosis; Depression; Disease Models, Animal; Humans; Imiprami | 1974 |
Proceedings: Drugs, mood, and amines: a profile in psychobiological research.
Topics: Animals; Antidepressive Agents; Biogenic Amines; Depression; Emotions; Humans; Imipramine; Methoxyhy | 1974 |
Amenorrhea: symptom of endogenous depression.
Topics: Adult; Amenorrhea; Carbonates; Depression; Female; Humans; Imipramine; Lithium | 1972 |
Averaged evoked responses (aer) in patients with affective disorders.
Topics: Acetophenones; Adjustment Disorders; Adult; Aged; Antidepressive Agents, Tricyclic; Brain; Depressio | 1974 |
Proceedings: Antagonism of nicotinic acid and other kynurenines to antidepressants: one of the probable reasons of the therapy-resistance in depression?
Topics: Allopurinol; Amitriptyline; Animals; Depression; Drug Interactions; Humans; Hypnotics and Sedatives; | 1974 |
Psychotic reactions during organ transplantation.
Topics: Cognition Disorders; Depression; Erectile Dysfunction; Female; Humans; Imipramine; Kidney Transplant | 1972 |
Prediction of drug effect in personality disorders.
Topics: Affective Symptoms; Chlorpromazine; Depression; Diagnosis, Computer-Assisted; Evaluation Studies as | 1973 |
[Therapy susceptibility to thymoleptics in depression].
Topics: Amitriptyline; Depression; Humans; Imipramine; Time Factors | 1972 |
The adverse influence of imipramine on the adaptation of the newborn infant to extrauterine life.
Topics: Cyanosis; Depression; Female; Fetal Diseases; Fetus; Heart Failure; Humans; Imipramine; Infant, Newb | 1972 |
Biogenic amines and their impact in psychiatry.
Topics: Amphetamine; Biogenic Amines; Brain; Depression; Ephedrine; Epinephrine; Humans; Imipramine; Mental | 1972 |
Sustained release amitriptyline (lentizol) in depressive illness.
Topics: Amitriptyline; Delayed-Action Preparations; Depression; Humans; Imipramine | 1973 |
Disrupted 24-hour patterns of cortisol secretion in psychotic depression.
Topics: Adrenal Glands; Adult; Aged; Circadian Rhythm; Depression; Electroconvulsive Therapy; Female; Humans | 1973 |
Plasma cortisol-binding capacity in mental illness.
Topics: Adult; Anxiety; Binding Sites; Bipolar Disorder; Chlorpromazine; Chromatography, Gel; Depression; Di | 1973 |
Single dose vs divided dose imipramine.
Topics: Adult; Depression; Female; Humans; Imipramine; Methods; Middle Aged; Psychiatric Status Rating Scale | 1973 |
[Influence of dibencycladine and imipramine on the caloric intake and body weight].
Topics: Acute Disease; Anthracenes; Antidepressive Agents; Body Weight; Depression; Feeding Behavior; Female | 1973 |
Concomitant imipramine and methylphenidate administration: a case report.
Topics: Depression; Drug Synergism; Humans; Imipramine; Male; Methylphenidate; Middle Aged; Remission, Spont | 1973 |
Imipramine in hyperacusic depression.
Topics: Affect; Auditory Threshold; Depression; Humans; Imipramine; Reflex, Startle | 1973 |
The treatment of depression with a single daily dose of imipramine pamoate.
Topics: Administration, Oral; Adult; Anxiety; Delayed-Action Preparations; Depression; Evaluation Studies as | 1973 |
Influence of affective states and psychoactive drugs on verbal learning and memory.
Topics: Bipolar Disorder; Carbonates; Depression; Dihydroxyphenylalanine; Humans; Imipramine; Lithium; Memor | 1973 |
Plasma binding of imipramine and clinical outcome.
Topics: Blood Proteins; Depression; Female; Humans; Imipramine; Middle Aged; Protein Binding | 1973 |
Is response to antidepressants an aid to the differentiation of response-specific types of depression?
Topics: Adult; Amitriptyline; Depression; Humans; Imipramine; Male; Middle Aged; Nialamide; Recurrence | 1973 |
Grief in the Navajo: psychodynamics and culture.
Topics: Adult; Crying; Culture; Depression; Female; Grief; Humans; Imipramine; Indians, North American; Male | 1973 |
Biological and pharmacokinetic evidence for generic equivalence of three imipramine preparations: comparison with a new imipramine analogue.
Topics: Animals; Depression; Desipramine; Humans; Imipramine; Iris; Norepinephrine; Solubility; Tablets; The | 1973 |
Treatment of depression with Sapilent.
Topics: Adult; Aged; Antidepressive Agents; Depression; Dibenzazepines; Drug Evaluation; Humans; Imipramine; | 1973 |
Measuring the pharmacological action of imipramine in the treatment of depressions.
Topics: Adjustment Disorders; Adult; Aged; Depression; Female; Humans; Imipramine; Male; Methods; Middle Age | 1974 |
Amitriptyline and imipramine poisoning in children.
Topics: Amitriptyline; Arrhythmias, Cardiac; Child, Preschool; Depression; Enuresis; Female; Humans; Imipram | 1974 |
The efficacy of antidepressant drugs. A review of research (1958-1972).
Topics: Adolescent; Adult; Aged; Amitriptyline; Antidepressive Agents; Bipolar Disorder; Depression; Dibenza | 1974 |
[Out-patient family therapy for a 14-year-old girl with anorexia nervosa].
Topics: Adolescent; Ambulatory Care; Anorexia Nervosa; Child; Depression; Family Therapy; Female; Humans; Im | 1974 |
[Therapy of severe pain due to injuries using tofranil].
Topics: Adult; Depression; Humans; Imipramine; Male; Pain; Pain, Postoperative; Phantom Limb; Wounds and Inj | 1974 |
Age-sex differences in response to antidepressant drugs.
Topics: Adjustment Disorders; Adolescent; Adult; Age Factors; Aged; Antidepressive Agents; Anxiety; Chlorpro | 1974 |
Amenorrhea in endogenous depression.
Topics: Adolescent; Adult; Amenorrhea; Bipolar Disorder; Depression; Female; Humans; Imipramine; Lithium; Pe | 1974 |
Differential diagnosis and treatment of depression in the elderly.
Topics: Adjustment Disorders; Aged; Antidepressive Agents; Circadian Rhythm; Dementia; Depression; Diagnosis | 1974 |
Treatment of the depressed outpatient.
Topics: Adolescent; Adult; Aged; Amitriptyline; Antidepressive Agents; Anxiety; Child; Chlordiazepoxide; Dep | 1974 |
Slow constant intravenous infusion of imipramine up to 850 mgm/day in patients with affective illness.
Topics: Blood; Depression; Female; Humans; Imipramine; Infusions, Parenteral; Substance Withdrawal Syndrome; | 1966 |
[Dangers of a too rapid substitution of imipramine for an inhibitor of monoamine oxidase and of the nialamide-isoniazid-barbiturate combination at high doses in psychiatric therapy].
Topics: Adult; Animals; Autonomic Nervous System; Barbiturates; Brain; Brain Chemistry; Catecholamines; Cats | 1967 |
Thioridazine in patients with depression.
Topics: Adolescent; Adult; Depression; Female; Humans; Imipramine; Mental Disorders; Middle Aged; Thioridazi | 1969 |
Evaluation of thiazesim (SQ 10,496) as an anti-depressant: a negative report.
Topics: Adult; Amitriptyline; Antidepressive Agents; Benzazepines; Depression; Female; Humans; Imipramine; M | 1969 |
The toxicologic and pharmacologic properties of amantadine hydrochloride.
Topics: Abnormalities, Drug-Induced; Acetylcholine; Amantadine; Analgesia; Animals; Arrhythmias, Cardiac; Bl | 1969 |
[Clinical study and electroencephalographic correlations of debenzepine].
Topics: Aged; Amitriptyline; Depression; Dibenzazepines; Electroencephalography; Female; Humans; Imipramine; | 1969 |
[Clinical study and electroencephalographic effects of mefexamide].
Topics: Acetates; Amitriptyline; Antidepressive Agents; Depression; Dibenzazepines; Drug Synergism; Electroe | 1969 |
A potential clinical use for methylphenidate with tricyclic antidepressants.
Topics: Adult; Aged; Animals; Chloral Hydrate; Chromatography, Thin Layer; Depression; Desipramine; Dextroam | 1971 |
[Study of depressive states following the intake of appetite depressants].
Topics: Adolescent; Adult; Anxiety; Appetite Depressants; Depression; Female; Humans; Imipramine; Male; Midd | 1972 |
Abnormalities of indoleamines in affective disorders.
Topics: Adult; Affective Symptoms; Biogenic Amines; Brain Chemistry; Depression; Drug Combinations; Evaluati | 1972 |
Safety of high-dose tricyclic antidepressant therapy.
Topics: Adolescent; Adult; Amitriptyline; Antidepressive Agents; Depression; Dibenzoxepins; Drug Labeling; D | 1972 |
The black cloud. The recognition and treatment of endogenous depression in general practice.
Topics: Amitriptyline; Australia; Depression; Electroconvulsive Therapy; Family Practice; Hospitalization; H | 1972 |
The tricyclic antidepressants.
Topics: Amitriptyline; Antidepressive Agents; Cardiovascular Diseases; Depression; Humans; Imipramine | 1972 |
Limb deformities associated with iminodibenzyl hydrochloride.
Topics: Abnormalities, Drug-Induced; Australia; Depression; Drug Labeling; Female; Humans; Imipramine; Socie | 1972 |
[Neuropsychiatric aspects of male sterility].
Topics: Amitriptyline; Depression; Dibenzazepines; Frustration; Humans; Imipramine; Infertility, Male; Male; | 1972 |
Drowsiness and antidepressant drugs in mild depressive illness.
Topics: Amitriptyline; Antidepressive Agents; Depression; Humans; Imipramine; Indoles; Methylamines; Sleep; | 1972 |
[Basic deliberations on empiric methodology in psychiatry].
Topics: Anxiety; Depression; Humans; Imipramine; Methods; Psychiatry; Research; Speech | 1972 |
Effect of iprindole on amine uptake in man.
Topics: Amines; Antidepressive Agents; Biogenic Amines; Blood Platelets; Blood Pressure; Brain Chemistry; Cy | 1972 |
[The use of psychotropic drugs in geriatrics].
Topics: Aged; Antidepressive Agents; Behavior; Dementia; Depression; Humans; Imipramine; Mental Disorders; T | 1972 |
[Depressive syndromes in patients over age 55. Diagnostic difficulties and therapeutic possibilities].
Topics: Age Factors; Aged; Depression; Diagnosis, Differential; Female; Humans; Imipramine; Male; Middle Age | 1972 |
Thyroid-imipramine clinical and chemical interaction: evidence for a receptor deficit in depression.
Topics: Adult; Catechols; Depression; Female; Glycols; Humans; Hydroxyindoleacetic Acid; Imipramine; Middle | 1972 |
Drugs of dependence though not of abuse: fenfluramine and imipramine.
Topics: Adult; Appetite Depressants; Body Weight; Depression; Dreams; Female; Fenfluramine; Fluorine; Humans | 1971 |
Differentiation of two genetically specific types of depression by the response to antidepressant drugs.
Topics: Amitriptyline; Antidepressive Agents; Depression; Female; Humans; Hydrazines; Imipramine; Male; Mono | 1971 |
Exploration of the anti-depressant potential of L-dopa.
Topics: Animals; Antidepressive Agents; Behavior; Blood Pressure; Carboxy-Lyases; Depression; Dihydroxypheny | 1971 |
The effects of antidepressant therapy. A follow-up study.
Topics: Antidepressive Agents; Bipolar Disorder; Depression; Depressive Disorder, Major; Drug Combinations; | 1971 |
Homovanillic and 5-hydroxyindoleacetic acid in cerebrospinal fluid of depressed patients.
Topics: Adult; Age Factors; Depression; Dexamethasone; Humans; Hydroxyindoleacetic Acid; Imipramine; Middle | 1971 |
Drug treatment of chronic intractable pain in patients referred to a psychiatry clinic.
Topics: Adolescent; Adult; Aged; Amitriptyline; Anxiety; Chlordiazepoxide; Chronic Disease; Depression; Fema | 1971 |
Two new antidepressive preparations.
Topics: Amitriptyline; Depression; Dibenzazepines; Humans; Imipramine; Injections, Intramuscular; Injections | 1971 |
Comparative trial of imipramine and dimethacrin in depressive states in a Nigerian patient population.
Topics: Acridines; Adult; Antidepressive Agents; Depression; Female; Humans; Imipramine; Male; Methylamines; | 1971 |
[Polythymolepsy (combined use of thymoleptics) in cases of endogenous depression].
Topics: Amitriptyline; Antidepressive Agents; Basal Ganglia Diseases; Depression; Dibenzazepines; Drug Thera | 1971 |
Pharmacotherapy in the premenstrual tension.
Topics: Adolescent; Adult; Bipolar Disorder; Chlorpromazine; Depression; Female; Humans; Imipramine; Neuroti | 1971 |
The effect of reserpine and nortriptyline on the excretion of 17-hydroxysteroids.
Topics: Animals; Apomorphine; Behavior, Animal; Depression; Drug Synergism; Grooming; Humans; Imipramine; Li | 1971 |
Drug treatment of depression.
Topics: Depression; Humans; Imipramine; Monoamine Oxidase Inhibitors; Nursing | 1966 |
[Differential therapeutic experiments with antidepressive efficacious psychopharmacotics].
Topics: Amitriptyline; Antidepressive Agents; Depression; Desipramine; Humans; Imipramine; Psychopharmacolog | 1967 |
[Autonomic effects of thymoleptics and their relationships to the antidepressive effect during the course of therapy].
Topics: Adult; Anthropometry; Antidepressive Agents; Autonomic Nervous System; Blood Circulation; Depression | 1970 |
[On the symptoms and therapy of depressive diseases diagnosed in early childhood].
Topics: Aggression; Body Weight; Child Behavior Disorders; Child, Preschool; Depression; Electroencephalogra | 1970 |
[Hidden depression--problem in internal medicine].
Topics: Anxiety; Depression; Fatigue; Feeding and Eating Disorders; Humans; Imipramine; Psychophysiologic Di | 1970 |
[Preliminary observations using I.H.B. 215 on depressive-anxiety states].
Topics: Adult; Aged; Anxiety; Chlordiazepoxide; Depression; Female; Humans; Imipramine; Male; Middle Aged | 1969 |
[The management of depressive conditions using monochloroimipramine by venous and oral administration].
Topics: Adult; Aged; Animals; Cats; Depression; Female; Humans; Imipramine; Male; Methods; Middle Aged | 1968 |
[Depressive syndromes. Evaluation of results in the use of various thymoanaleptics].
Topics: Adult; Antidepressive Agents; Depression; Humans; Imipramine; Liver Function Tests; Middle Aged; Mon | 1968 |
Measurement of mood.
Topics: Affective Symptoms; Amitriptyline; Anthropometry; Antidepressive Agents; Bipolar Disorder; Depressio | 1969 |
Effects of imipramine and reserpine in depression.
Topics: Depression; Female; Humans; Imipramine; Male; Middle Aged; Psychiatric Status Rating Scales; Reserpi | 1969 |
[Ambulatory care of depressive mental disorders with Anafranil in neurologic practice].
Topics: Adult; Antidepressive Agents; Azepines; Depression; Female; Humans; Imipramine; Male; Middle Aged; P | 1969 |
New treatment as a stimulus for replication of research.
Topics: Depression; Humans; Imipramine; Research; Thyroid Hormones | 1969 |
[Sensitivo-motor polyneuritis during prolonged treatment by imipramine].
Topics: Depression; Humans; Imipramine; Male; Middle Aged; Polyneuropathies; Time Factors | 1969 |
[Effect of thymoleptics on acid production of the stomach. Preliminary report].
Topics: Amitriptyline; Chlorpromazine; Depression; Depression, Chemical; Desipramine; Dibenzazepines; Gastri | 1969 |
A case of periodic somnolence whose sleep was induced by glucose.
Topics: Adolescent; Adult; Carbamazepine; Depression; Electroencephalography; Food Preferences; Glucose; Hum | 1969 |
Differential response to treatment as a function of the changing character of a depression.
Topics: Depression; Humans; Imipramine; Male; Middle Aged; Psychology; Suicide; Tranylcypromine | 1970 |
Imipramine effects upon hostility in depression.
Topics: Adult; Aged; Analysis of Variance; Depression; Female; Hospitalization; Hostility; Humans; Imipramin | 1970 |
[Current problems of endogenous depression].
Topics: Amitriptyline; Antidepressive Agents; Chlorpromazine; Convulsive Therapy; Depression; Desipramine; F | 1970 |
[Clinical antidepressant drug therapy].
Topics: Amitriptyline; Antidepressive Agents; Depression; Desipramine; Dibenzazepines; Humans; Imipramine; N | 1970 |
Depressive illness in general practice.
Topics: Depression; Family Practice; Humans; Imipramine | 1970 |
The effects of imipramine and electric convulsive therapy on the excretion of various minerals in depressed patients.
Topics: Depression; Electroconvulsive Therapy; Female; Humans; Imipramine; Magnesium; Male; Phosphates; Pota | 1970 |
Thyroid hormone and tricyclic antidepressants in resistant depressions.
Topics: Adult; Amitriptyline; Antidepressive Agents; Depression; Drug Synergism; Female; Humans; Imipramine; | 1970 |
Differentiation of two genetically specific types of depression by the response to antidepressant drugs.
Topics: Antidepressive Agents; Depression; Diagnosis, Differential; Humans; Imipramine; Monoamine Oxidase In | 1970 |
Studies of mineral metabolism in mental depression. I. The effects of imipramine and electric convulsive therapy on calcium balance and kinetics.
Topics: Adult; Aged; Calcium; Depression; Electroconvulsive Therapy; Female; Humans; Imipramine; Kinetics; M | 1970 |
Imipramine and lithium effects of biogenic amine transport in depressed and manic-depressed patients.
Topics: Animals; Biological Transport; Bipolar Disorder; Blood Platelets; Brain; Cell Membrane; Depression; | 1970 |
Psychic effects in patients treated with levodopa.
Topics: Aged; Depression; Dihydroxyphenylalanine; Female; Humans; Imipramine; Middle Aged; Parkinson Disease | 1970 |
Enhancement of imipramine by thyroid stimulating hormone: clinical and theoretical implications.
Topics: Adult; Depression; Drug Synergism; Female; Humans; Imipramine; Male; Middle Aged; Psychiatric Status | 1970 |
Noveril (dibenzepin)--another new antidepressive.
Topics: Amitriptyline; Antidepressive Agents; Depression; Dibenzazepines; Humans; Imipramine; Nortriptyline | 1970 |
Antianxiety and anti-depressant drugs.
Topics: Amitriptyline; Antidepressive Agents; Anxiety; Chlordiazepoxide; Depression; Desipramine; Dibenzoxep | 1970 |
[Three cases of action myoclonus during treatment with imipramine and amitriptyline].
Topics: Aged; Amitriptyline; Depression; Electromyography; Female; Humans; Imipramine; Middle Aged; Myoclonu | 1970 |
[Psychosensory phenomena during treatment with tricyclic thymoanaleptics (presentation of 2 cases)].
Topics: Depression; Desipramine; Female; Hallucinations; Humans; Imipramine; Male; Middle Aged; Tranquilizin | 1970 |
[Combination treatment of engodenous depressions].
Topics: Adult; Aged; Amitriptyline; Depression; Humans; Imipramine; Male; Middle Aged | 1970 |
Monoamine oxidase inhibitors, combined with thymoleptics: Are they really unusable for human beings?
Topics: Animals; Behavior, Animal; Brain Chemistry; Brain Stem; Butyrophenones; Depression; Fluorescence; Hu | 1970 |
[Complications caused by anonymous preclinical medication].
Topics: Amitriptyline; Antidepressive Agents; Barbiturates; Bromides; Cannabis; Chlordiazepoxide; Delirium; | 1970 |
[Dream activation by thymoleptics].
Topics: Amitriptyline; Antidepressive Agents; Depression; Depression, Chemical; Diazepam; Dibenzazepines; Dr | 1970 |
[Intragastric telemetric pH measuring during thymoleptic therapy].
Topics: Amitriptyline; Depression; Depression, Chemical; Desipramine; Dibenzazepines; Female; Gastric Acidit | 1970 |
Clinical and metabolic studies with imipramine in man.
Topics: Anxiety; Depression; Dextroamphetamine; Female; Humans; Imipramine; Male; Methylphenidate; Psychiatr | 1971 |
Clinical significance of plasma imipramine levels.
Topics: Depression; Female; Humans; Imipramine; Male; Psychiatric Status Rating Scales | 1971 |
[Mechanisms of short-term memory].
Topics: Amobarbital; Amphetamine; Chlorpromazine; Depression; Humans; Hypothalamus; Imipramine; Memory, Shor | 1971 |
[Depressive syndromes in childhood and adolescence. Symptomatology, etiology and prognosis].
Topics: Adolescent; Age Factors; Child; Child Development; Child Psychiatry; Child, Hospitalized; Child, Pre | 1971 |
[Clinical evaluation of antidepressive effects of doxepin].
Topics: Adjustment Disorders; Adolescent; Adult; Aged; Depression; Dibenzoxepins; Female; Humans; Imipramine | 1971 |
Combined antidepressant therapy.
Topics: Adjustment Disorders; Adult; Amitriptyline; Depression; Electroconvulsive Therapy; Female; Humans; I | 1971 |
[New drugs. 5].
Topics: Anthracenes; Depression; Gentamicins; Humans; Imipramine; Lincomycin; Osteomyelitis; Respiratory Tra | 1971 |
Tricyclic antidepressants and monoamine oxidase inhibitors.
Topics: Administration, Oral; Adolescent; Adult; Aged; Amitriptyline; Animals; Depression; Desipramine; Drug | 1971 |
[Comparative clinical-experimental studies on imipramine and desipramine].
Topics: Blood Circulation; Blood Pressure; Depression; Desipramine; Drug Synergism; Heart; Humans; Imipramin | 1967 |
[The treatment of endogenous depression with chlorimipramine (Anafranil)].
Topics: Adult; Aged; Cardiovascular System; Depression; Dibenzazepines; Electroencephalography; Female; Huma | 1967 |
[Clinical trial of the new antidepressive agent imipramine-N-oxide].
Topics: Depression; Female; Humans; Imipramine; Male | 1967 |
[Anafranil: a new strongly effective antidepressive in neurological practice].
Topics: Adult; Aged; Depression; Female; Humans; Imipramine; Male; Middle Aged | 1967 |
[Comparative clinical experiences with dibenzazepine and dibenzodiazepine derivatives].
Topics: Antidepressive Agents; Depression; Desipramine; Dibenzazepines; Humans; Imipramine; Middle Aged; Sch | 1967 |
Imipramine (Melipramine) therapy of depressions imitating internal diseases.
Topics: Depression; Humans; Imipramine; Psychophysiologic Disorders | 1968 |
Recognition of depression.
Topics: Aged; Aging; Amitriptyline; Brain Damage, Chronic; Depression; Humans; Imipramine; Social Isolation; | 1968 |
Effect of imipramine, physostigmine and amphetamine on the electrical activity of the brain in the cat.
Topics: Amphetamine; Amygdala; Animals; Arousal; Cats; Cerebral Cortex; Cerebral Ventricles; Depression; Ele | 1968 |
Allergy sympton survey. Evaluation of emotional content in allergy.
Topics: Anxiety; Chlordiazepoxide; Depression; Humans; Hypersensitivity; Imipramine; Psychophysiologic Disor | 1968 |
[Comparative characteristics of the effect of melipramine on the bio-electric activity of the brain in patients with circular depression and paranoid schizophrenia].
Topics: Brain; Depression; Electroencephalography; Female; Humans; Imipramine; Injections, Intramuscular; Pa | 1968 |
[1st observations on the use of chlor-imipramine (G 34586) in a group of depressive patients].
Topics: Adult; Depression; Female; Humans; Imipramine; Male; Middle Aged; Schizophrenia | 1968 |
[Recent acquisitions on the therapy of depression: from unilateral electroshock to the use of lithium salts].
Topics: Amitriptyline; Depression; Dominance, Cerebral; Electroconvulsive Therapy; Electrodes; Humans; Imipr | 1968 |
[Tryptophan metabolism during depression].
Topics: Amitriptyline; Depression; Female; Humans; Hydrazines; Imipramine; Male; Serotonin; Tranylcypromine; | 1968 |
[Response to psychotropic drugs in depressive syndromes. Clinico-statistical contribution].
Topics: Antidepressive Agents; Depression; Desipramine; Humans; Imipramine; Monoamine Oxidase Inhibitors | 1968 |
Imipramine antagonism of the CNS effects of norepinephrine; behavioral and neurochemical correlates.
Topics: Animals; Brain Chemistry; Chickens; Depression; Humans; Imipramine; Motor Activity; Norepinephrine; | 1968 |
[Contribution to the clinical evaluation of the antidepressive effect of dimethacrine (Istonil)].
Topics: Antidepressive Agents; Depression; Humans; Imipramine | 1968 |
[Experiences with the treatment of endogenous depressions with anafranil].
Topics: Azepines; Depression; Electroconvulsive Therapy; Humans; Imipramine; Methods | 1969 |
Clinical significance of anticholinergic effects of imipramine-like drugs.
Topics: Amitriptyline; Animals; Atropine; Columbidae; Depression; Desipramine; Diphenhydramine; Humans; Imip | 1969 |
Masked depression and the use of antidepressants in general practice.
Topics: Adult; Age Factors; Amitriptyline; Antidepressive Agents; Depression; Family Practice; Female; Human | 1969 |
Sodium transfer from plasma to CSF in severe depressive illness.
Topics: Aged; Blood-Brain Barrier; Depression; Dexamethasone; Electroconvulsive Therapy; Female; Humans; Hyd | 1969 |
[On the psychopharmalogic characteristics and a clinical evaluation of the therapeutic effect of antidepressants].
Topics: Animals; Antidepressive Agents; Chemical Phenomena; Chemistry; Depression; Humans; Imipramine; Monoa | 1969 |
Drugs for patients with concurrent anxiety and depression.
Topics: Amitriptyline; Antidepressive Agents; Anxiety; Depression; Humans; Imipramine; Phenelzine | 1969 |
Fatal myocardial infarction associated with sub-clinical doses of imipramine.
Topics: Depression; Humans; Imipramine; Male; Middle Aged; Myocardial Infarction | 1969 |
[Clinical-psychiatric observations with noxiptilin in depressive syndromes].
Topics: Adjustment Disorders; Amitriptyline; Antidepressive Agents; Bipolar Disorder; Chlorpromazine; Depres | 1969 |
Do psyhiatric out-patients take their drugs?
Topics: Chlorpromazine; Chromatography; Depression; Female; Humans; Imipramine; Male; Mental Disorders; Psyc | 1965 |
[Pharmaclogical modification of depressive symptoms].
Topics: Antidepressive Agents; Depression; Humans; Imipramine; Monoamine Oxidase Inhibitors | 1965 |
A comparison of two antidepressant drugs.
Topics: Adult; Aging; Depression; Female; Humans; Imipramine; Male; Middle Aged; Phenelzine; Sex | 1964 |
Differences in the metabolism of norepinephrine in depressions. The effects of various therapies.
Topics: Adult; Aged; Amitriptyline; Brain; Chlorpromazine; Depression; Electroconvulsive Therapy; Female; Hu | 1965 |
Antidepressive drugs.
Topics: Adolescent; Adult; Aged; Amitriptyline; Amphetamine; Antidepressive Agents; Classification; Depressi | 1965 |
Desipramine and imipramine in an outpatient setting: a comparative study.
Topics: Adolescent; Adult; Depression; Desipramine; Humans; Imipramine; Middle Aged | 1965 |
Preliminary evaluation of a new anti-depressant, trimipramine, by a sequential method.
Topics: Antidepressive Agents; Depression; Female; Humans; Imipramine; Male; Psychotic Disorders; Statistics | 1965 |
[Use of imipramine as an adjunct in therapy of depression].
Topics: Adolescent; Adult; Aged; Depression; Humans; Imipramine; Middle Aged | 1965 |
Catecholamine metabolism in affective disorders. I. Normetanephrine and VMA excretion in depressed patients treated with imipramine.
Topics: Depression; Female; Humans; Imipramine; Mandelic Acids; Middle Aged; Normetanephrine; Placebos; Urin | 1965 |
[Tofranil therapy of depression in adolescent disorders].
Topics: Adolescent; Depression; Humans; Imipramine | 1965 |
Preliminary comparative trial of proheptatriene and imipramine in the treatment of depressions. (An intensive and controlled study).
Topics: Antidepressive Agents; Depression; Humans; Imipramine | 1965 |
The therapeutic effect of imipramine in repeated phases of endogenous depression in the same individual.
Topics: Depression; Female; Humans; Imipramine; Male; Middle Aged | 1965 |
New treatment of some chronic tension states.
Topics: Adult; Aged; Amitriptyline; Antidepressive Agents; Anxiety; Chlorpromazine; Depression; Electroconvu | 1966 |
Geriatric patients treated with imipramine: five-year follow-up.
Topics: Aged; Depression; Female; Follow-Up Studies; Humans; Imipramine; Male | 1966 |
Drugs for depression.
Topics: Amitriptyline; Amphetamine; Depression; Electroconvulsive Therapy; Humans; Imipramine; Monoamine Oxi | 1966 |
[Treatment of depressive states with chlorimipramine (G 34,586) administered by slow venous perfusion].
Topics: Aged; Antidepressive Agents; Depression; Female; Humans; Imipramine; Male | 1966 |
Combined drug and psychotherapy of severely depressed ambulatory patients.
Topics: Antidepressive Agents; Depression; Humans; Imipramine; Iproniazid; Psychoanalytic Therapy; Psychothe | 1966 |
Withdrawal symptoms after abrupt termination of imipramine.
Topics: Adult; Depression; Drug Tolerance; Humans; Imipramine; Male; Parent-Child Relations; Personality; Su | 1966 |
Dreaming in the depressed.
Topics: Adult; Bipolar Disorder; Depression; Depressive Disorder, Major; Dreams; Female; Humans; Imipramine; | 1966 |
The metabolism of norepinephrine in depressions. Differences and effects of therapies.
Topics: Adult; Aged; Amitriptyline; Bipolar Disorder; Chlordiazepoxide; Chlorpromazine; Depression; Depressi | 1966 |
[Action of tofranil on the human embryo].
Topics: Adult; Depression; Female; Fetus; Humans; Imipramine; Infant, Newborn; Pregnancy; Pregnancy Complica | 1966 |
Nosology of depression and differential response to drugs.
Topics: Classification; Depression; Humans; Imipramine; Psychoanalysis; Thioridazine | 1966 |
[Contribution to the study of depression in children and its treatment with imipramine].
Topics: Adolescent; Child; Child Behavior Disorders; Depression; Female; Humans; Imipramine; Male | 1966 |
Visual hallucinations with iminodibenzyl ANTIDEPRESSANTS.
Topics: Adult; Amitriptyline; Depression; Female; Hallucinations; Humans; Imipramine; Middle Aged | 1966 |
The real effect of imipramine, isocarboxazid and nialamide.
Topics: Adult; Depression; Humans; Imipramine; Isocarboxazid; Nialamide | 1966 |
[Our experience with the treatment of depressive status with deprenil--Polfa].
Topics: Depression; Humans; Imipramine | 1966 |
[Our experience with the treatment of depressive status with deprenil--Polfa].
Topics: Depression; Humans; Imipramine | 1966 |
[Combined therapy in endogenous depression].
Topics: Antidepressive Agents; Depression; Depressive Disorder, Major; Humans; Imipramine; Thioridazine | 1966 |
[Problems of psychopharmacotherapy].
Topics: Adolescent; Antidepressive Agents; Depression; Humans; Imipramine; Mental Disorders; Psychopharmacol | 1966 |