substance p has been researched along with Depression in 38 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (2.63) | 18.7374 |
| 1990's | 3 (7.89) | 18.2507 |
| 2000's | 21 (55.26) | 29.6817 |
| 2010's | 12 (31.58) | 24.3611 |
| 2020's | 1 (2.63) | 2.80 |
| Authors | Studies |
|---|---|
| Duan, XH; Huang, YZ; Liu, WL; Su, KH; Wang, T; Yan, YF; Yang, L | 1 |
| Bai, XG; Hao, LY; Huang, SS; Huang, YP; Li, ZY; Wang, ZL; Xia, XC; Zhang, JF; Zhao, ML; Zheng, XH | 1 |
| Chen, X; Chu, B; Dai, W; Dong, Z; Hu, Y; Liang, J; Pan, M; Yu, S; Zhang, M | 1 |
| Arora, V; Chopra, K | 1 |
| Jin, HJ; Yang, LM; Yu, L; Zhao, H | 1 |
| Baqi, Y; Correa, M; Freeland, C; Hart, EE; López-Cruz, L; Müller, CE; Nunes, EJ; Randall, PA; Salamone, JD; Yohn, SE | 1 |
| Coveñas, R; Muñoz, M | 1 |
| Deng, X; Fu, SK; Li, J; Ren, L; Sun, JD; Zhao, SZ | 1 |
| Groffik, A; Hawro, T; Krull, C; Maurer, M; Metz, M; Saluja, R; Stanger, C; Staubach, P | 1 |
| Huang, GY; Li, SQ; Tian, M; Wang, Y; Xiong, F; Zheng, CH | 1 |
| Sümegi, A | 1 |
| Akhmedov, VA; Ostapenko, VA | 1 |
| Gao, X; Ji, X; Li, L; Luo, Y; Wei, H; Zhao, J | 1 |
| Bae, BG; Lee, KH; Noh, JY; Oh, SH; Park, CO; Park, IH; Wu, WH | 1 |
| Chen, X; Dong, Z; Li, Z; Liang, J; Liu, R; Wang, X; Yu, S | 1 |
| Hunt, SP; Kelly, JP; Kerr, DM; Roche, M | 1 |
| Bilkei-Gorzo, A; Michel, K; Racz, I; Zimmer, A | 1 |
| Berger, M; Fiebich, BL; Herpfer, I; Lieb, K | 1 |
| Leserman, J | 1 |
| Holden, C | 1 |
| Adell, A | 1 |
| Duffy, RA | 1 |
| Bjørnebekk, A; Brené, S; Mathé, AA | 1 |
| McLean, S | 1 |
| Chourbaji, S; Gass, P; Urani, A | 1 |
| Ebner, K; Singewald, N | 1 |
| Braw, Y; Malkesman, O; Weller, A | 1 |
| Andersson, W; Bolwig, TG; Husum, H; Mathé, AA; Wörtwein, G | 1 |
| Eichling, PS; Sahni, J | 1 |
| Feige, B; Fiebich, BL; Herpfer, I; Katzev, M; Lieb, K; Voderholzer, U | 1 |
| Bucinskaite, V; Crumpton, K; Ekblom, A; Lundeberg, T; Stenfors, C; Theodorsson, E | 1 |
| Baby, S; Nguyen, M; Raffa, RB; Tran, D | 1 |
| Witonski, D | 1 |
| Berger, M; Fiebich, BL; Lieb, K | 1 |
| DeVane, CL | 1 |
| Rupniak, NM | 1 |
| Almay, BGL; Johansson, F; Le Grevés, P; Terenius, L; Von Knorring, L | 1 |
13 review(s) available for substance p and Depression
| Article | Year |
|---|---|
Involvement of substance P and the NK-1 receptor in human pathology.
Topics: Alcoholism; Animals; Bacterial Infections; Depression; Humans; Inflammation; Migraine Disorders; Neoplasms; Pain; Receptors, Neurokinin-1; Seizures; Stress, Psychological; Substance P; Virus Diseases; Vomiting | 2014 |
[Domino principle--monoamines in bottom-view].
Topics: Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents; Biogenic Monoamines; Corticotropin-Releasing Hormone; Depression; Depressive Disorder; Dopamine Uptake Inhibitors; Galanin; Humans; Locus Coeruleus; Neuropeptide Y; Neuropeptides; Neurotransmitter Agents; Norepinephrine; Raphe Nuclei; Selective Serotonin Reuptake Inhibitors; Serotonin; Substance P | 2008 |
HIV disease progression: depression, stress, and possible mechanisms.
Topics: Catecholamines; Depression; Disease Progression; Glucocorticoids; HIV Infections; Humans; Stress, Psychological; Substance P | 2003 |
Antidepressant properties of substance P antagonists: relationship to monoaminergic mechanisms?
Topics: Animals; Antidepressive Agents; Biogenic Monoamines; Brain; Brain Chemistry; Depression; Depressive Disorder; Humans; Neurokinin-1 Receptor Antagonists; Neurons; Receptors, Neurokinin-1; Serotonin; Substance P; Tissue Distribution | 2004 |
Potential therapeutic targets for neurokinin-1 receptor antagonists.
Topics: Analgesics; Anti-Anxiety Agents; Anti-Asthmatic Agents; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents; Antiemetics; Antineoplastic Agents; Antitussive Agents; Anxiety; Asthma; Clinical Trials as Topic; Cough; Cystitis; Depression; Drug Design; Humans; Inflammation; Irritable Bowel Syndrome; Neoplasms; Neurokinin-1 Receptor Antagonists; Pain; Substance P; Vomiting | 2004 |
Do substance P and the NK1 receptor have a role in depression and anxiety?
Topics: Amygdala; Animals; Anxiety; Depression; Frontal Lobe; Humans; Locus Coeruleus; Neurokinin-1 Receptor Antagonists; Raphe Nuclei; Receptors, Neurokinin-1; Substance P | 2005 |
Mutant mouse models of depression: candidate genes and current mouse lines.
Topics: Animals; Biogenic Monoamines; Depression; Disease Models, Animal; Humans; Hypothalamo-Hypophyseal System; Interleukins; Mice; Mice, Mutant Strains; Models, Neurological; Nerve Growth Factors; Neuropeptide Y; Pituitary-Adrenal System; Receptors, Neurokinin-1; Substance P | 2005 |
The role of substance P in stress and anxiety responses.
Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Brain; Depression; Humans; Hypothalamo-Hypophyseal System; Mood Disorders; Neurokinin-1 Receptor Antagonists; Pituitary-Adrenal System; Psychotropic Drugs; Receptors, Neurokinin-1; Serotonin; Stress, Physiological; Substance P; Synaptic Transmission | 2006 |
Menopause related sleep disorders.
Topics: Depression; Estrogen Replacement Therapy; Estrogens; Female; Fibromyalgia; Humans; Hydrocortisone; Melatonin; Menopause; Phytotherapy; Polysomnography; Progesterone; Serotonin; Sleep Apnea Syndromes; Sleep Initiation and Maintenance Disorders; Sleep Stages; Substance P; Testosterone | 2005 |
Substance P antagonists: the next breakthrough in treating depression?
Topics: Animals; Antidepressive Agents; Clinical Trials as Topic; Depression; Disease Models, Animal; Forecasting; Humans; Receptors, Neurokinin-1; Substance P | 1999 |
[Substance P receptor antagonists--a new antidepressive and anxiolytic mechanism?].
Topics: Anti-Anxiety Agents; Antidepressive Agents, Second-Generation; Anxiety Disorders; Aprepitant; Depression; Humans; Morpholines; Neurokinin-1 Receptor Antagonists; Substance P | 2000 |
Substance P: a new era, a new role.
Topics: Animals; Antidepressive Agents, Second-Generation; Aprepitant; Depression; Humans; Morpholines; Neuropeptides; Pain; Stress, Psychological; Substance P; Synaptic Transmission | 2001 |
New insights into the antidepressant actions of substance P (NK1 receptor) antagonists.
Topics: Animals; Antidepressive Agents; Brain; Depression; Humans; Neurokinin-1 Receptor Antagonists; Receptors, Neurokinin-1; Substance P | 2002 |
2 trial(s) available for substance p and Depression
| Article | Year |
|---|---|
Clinical study of electro-acupuncture treatment with different intensities for functional constipation patients.
Topics: Acupuncture Points; Adolescent; Adult; Analysis of Variance; Anxiety; Constipation; Defecation; Depression; Electroacupuncture; Female; Humans; Hydrocortisone; Male; Middle Aged; Outcome Assessment, Health Care; Substance P; Time Factors; Treatment Outcome; Vasoactive Intestinal Peptide; Young Adult | 2014 |
Effects of substance P on memory and mood in healthy male subjects.
Topics: Adult; Affect; Anxiety; Attention; Autonomic Nervous System; Cross-Over Studies; Depression; Double-Blind Method; Humans; Infusions, Intravenous; Male; Memory, Short-Term; Mental Recall; Neuropsychological Tests; Personality Inventory; Substance P; Vasodilation | 2007 |
23 other study(ies) available for substance p and Depression
| Article | Year |
|---|---|
Effects of Zuojin pill on depressive behavior and gastrointestinal function in rats with chronic unpredictable mild stress: Role of the brain-gut axis.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Biogenic Monoamines; Brain; Chronic Disease; Cytokines; Depression; Drugs, Chinese Herbal; Gastrins; Gastrointestinal Transit; Glucagon-Like Peptide 1; Intestine, Small; Male; Motilin; Rats, Sprague-Dawley; Stress, Psychological; Substance P; Vasoactive Intestinal Peptide | 2020 |
[Correlation of behavioral performance with expressions of substance P and neurokinin-1 receptor in the L5－S2 spinal cord of chronic prostatitis rats].
Topics: Animals; Behavior, Animal; Depression; Interleukin-10; Interleukin-1beta; Interleukin-2; Male; Prostatitis; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Spinal Cord; Substance P; Tumor Necrosis Factor-alpha | 2019 |
Effects of UCMS-induced depression on nociceptive behaviors induced by electrical stimulation of the dura mater.
Topics: Animals; Calcitonin Gene-Related Peptide; Depression; Disease Models, Animal; Dura Mater; Electric Stimulation; Male; Nociception; Rats; Rats, Sprague-Dawley; Stress, Physiological; Substance P | 2013 |
Possible involvement of oxido-nitrosative stress induced neuro-inflammatory cascade and monoaminergic pathway: underpinning the correlation between nociceptive and depressive behaviour in a rodent model.
Topics: Animals; Berberine; Caspase 3; Cerebral Cortex; Depression; Disease Models, Animal; Dopamine; Hippocampus; Hyperalgesia; Interleukin-1beta; Male; NF-kappa B; Nitrites; Nociception; Norepinephrine; Oxidative Stress; Pain; Rats, Wistar; Reserpine; Serotonin; Signal Transduction; Substance P; Superoxide Dismutase | 2013 |
Substance P receptor antagonist in lateral habenula improves rat depression-like behavior.
Topics: Animals; Chromatography, High Pressure Liquid; Depression; Disease Models, Animal; Habenula; Injections, Intraventricular; Male; Microdialysis; Microinjections; Neurokinin-1 Receptor Antagonists; Raphe Nuclei; Rats; Rats, Wistar; Serotonin; Substance P | 2014 |
Effort-related motivational effects of the VMAT-2 inhibitor tetrabenazine: implications for animal models of the motivational symptoms of depression.
Topics: Adenosine A2 Receptor Antagonists; Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents, Second-Generation; Behavior, Animal; Bupropion; Conditioning, Operant; Depression; Disease Models, Animal; Dopamine; Dopamine and cAMP-Regulated Phosphoprotein 32; Enkephalins; Feeding Behavior; Immunohistochemistry; Male; Microdialysis; Motivation; Nucleus Accumbens; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Substance P; Tetrabenazine; Vesicular Monoamine Transport Proteins; Xanthines | 2013 |
[Effect of electroacupuncture stimulation of "Ganshu" (BL 18) on locomotor, gastric mucosal and hypothalamic SP immunoactivity and hippocampal 5-HT content in rats with depression and gastric ulcer].
Topics: Acupuncture Points; Animals; Depression; Disease Models, Animal; Electroacupuncture; Gastric Mucosa; Hippocampus; Humans; Male; Rats; Rats, Sprague-Dawley; Serotonin; Stomach Ulcer; Substance P | 2014 |
Substance P is upregulated in the serum of patients with chronic spontaneous urticaria.
Topics: Anxiety; Biomarkers; Chronic Disease; Depression; Disease Progression; Germany; Humans; Quality of Life; Severity of Illness Index; Substance P; Up-Regulation; Urticaria | 2014 |
[Psychoemotional and humoral changes in patients with combined reflux disorders].
Topics: Adolescent; Adult; Affective Symptoms; Anxiety; Autonomic Nervous System; Case-Control Studies; Depression; Duodenogastric Reflux; Female; Gastroesophageal Reflux; Gastrointestinal Motility; Humans; Male; Middle Aged; Neuropsychological Tests; Psychophysiologic Disorders; Substance P; Young Adult | 2009 |
Plasma and cerebrospinal fluid substance P in post-stroke patients with depression.
Topics: Adult; Aged; Aged, 80 and over; Brain; Depression; Female; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Severity of Illness Index; Stroke; Substance P | 2009 |
Association of stress with symptoms of atopic dermatitis.
Topics: Adolescent; Adult; Anxiety; Biopsy; Case-Control Studies; Child; Depression; Dermatitis, Atopic; Female; Humans; Immunohistochemistry; Male; Middle Aged; Nerve Growth Factor; Neuropeptide Y; Prognosis; Pruritus; Quality of Life; Receptors, Corticotropin-Releasing Hormone; Republic of Korea; Severity of Illness Index; Skin; Stress, Psychological; Substance P; Surveys and Questionnaires; Young Adult | 2010 |
The effects of OB-induced depression on nociceptive behaviors induced by electrical stimulation of the dura mater surrounding the superior sagittal sinus.
Topics: Amitriptyline; Animals; Antidepressive Agents; Depression; Disease Models, Animal; Dura Mater; Electric Stimulation; Male; Migraine Disorders; Olfactory Bulb; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Substance P; Superior Sagittal Sinus | 2011 |
Neurokinin-1 receptor deletion modulates behavioural and neurochemical alterations in an animal model of depression.
Topics: Animals; Biogenic Monoamines; Brain; Depression; Disease Models, Animal; Exploratory Behavior; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Olfactory Bulb; Receptors, Neurokinin-1; Substance P | 2012 |
Diminished anxiety- and depression-related behaviors in mice with selective deletion of the Tac1 gene.
Topics: Animals; Anxiety; Behavior, Animal; Depression; Male; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Knockout; Models, Animal; Motor Activity; Neurokinin A; Neurosurgical Procedures; Olfactory Bulb; Smell; Social Behavior; Spatial Behavior; Stress, Physiological; Substance P | 2002 |
[Substance P-antagonists as a new class of antidepressant drugs].
Topics: Animals; Antidepressive Agents; Aprepitant; Depression; Double-Blind Method; Humans; Mice; Mice, Knockout; Morpholines; Neurokinin-1 Receptor Antagonists; Placebos; Randomized Controlled Trials as Topic; Rats; Substance P; Time Factors | 2002 |
Future brightening for depression treatments.
Topics: Adult; Animals; Antidepressive Agents; Brain; Child; Clinical Trials as Topic; Corticotropin-Releasing Hormone; Depression; Depressive Disorder; Dopamine Agents; Electric Stimulation Therapy; Electroconvulsive Therapy; Humans; Magnetics; Neurons; Phosphodiesterase Inhibitors; Psychotherapy; Receptors, N-Methyl-D-Aspartate; Stress, Psychological; Substance P | 2003 |
The antidepressant effect of running is associated with increased hippocampal cell proliferation.
Topics: Analysis of Variance; Animals; Antidepressive Agents; Behavior, Animal; Body Weight; Brain-Derived Neurotrophic Factor; Bromodeoxyuridine; Cell Count; Cell Proliferation; Depression; Disease Models, Animal; Dynorphins; Enkephalins; Freezing Reaction, Cataleptic; Hippocampus; Immunohistochemistry; In Situ Hybridization; Male; Rats; Rats, Inbred Strains; RNA, Messenger; Running; Substance P | 2005 |
Assessment of antidepressant and anxiolytic properties of NK1 antagonists and substance P in Wistar Kyoto rats.
Topics: Analysis of Variance; Animals; Antidepressive Agents; Behavior, Animal; Depression; Disease Models, Animal; Exploratory Behavior; Hypothalamus; Male; Rats; Rats, Inbred WKY; Rats, Wistar; Substance P; Swimming | 2007 |
Gene-environment interaction affects substance P and neurokinin A in the entorhinal cortex and periaqueductal grey in a genetic animal model of depression: implications for the pathophysiology of depression.
Topics: Adrenal Glands; Animals; Anxiety, Separation; Body Weight; Corticotropin-Releasing Hormone; Depression; Entorhinal Cortex; Immunochemistry; Male; Neurokinin A; Occipital Lobe; Organ Size; Periaqueductal Gray; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Social Isolation; Substance P | 2008 |
Effects of repeated sensory stimulation (electro-acupuncture) and physical exercise (running) on open-field behaviour and concentrations of neuropeptides in the hippocampus in WKY and SHR rats.
Topics: Animals; Depression; Electric Stimulation; Electroacupuncture; Exploratory Behavior; Galanin; Hippocampus; Hypertension; Male; Neurokinin A; Neuropeptide Y; Neuropeptides; Physical Exertion; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Substance P; Vasoactive Intestinal Peptide | 1996 |
Anterior knee pain syndrome.
Topics: Adolescent; Adult; Aged; Analysis of Variance; Arthralgia; Depression; Female; Humans; Joint Instability; Knee Joint; Male; Middle Aged; Personality Inventory; Range of Motion, Articular; Substance P | 1999 |
Depression. Five new treatments.
Topics: Antidepressive Agents; Depression; Depressive Disorder; Electric Stimulation Therapy; Humans; Hydrocortisone; Magnetics; Morpholines; Reboxetine; Substance P; Vagus Nerve | 2000 |
Substance P in CSF of patients with chronic pain syndromes.
Topics: Adult; Aged; Chronic Disease; Depression; Female; Humans; Male; Middle Aged; Nervous System Diseases; Pain; Pain, Intractable; Personality Inventory; Substance P; Syndrome | 1988 |