Page last updated: 2024-09-03

4-(alpha-(4-allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl)-n,n-diethylbenzamide and Depression

4-(alpha-(4-allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl)-n,n-diethylbenzamide has been researched along with Depression in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (44.44)29.6817
2010's4 (44.44)24.3611
2020's1 (11.11)2.80

Authors

AuthorsStudies
Liu, J; Ning, K; Wang, Y; Wu, S; Zhang, L1
Chandra, R; Cheer, JF; Dias, C; Francis, TC; Lobo, MK; Nam, H1
Gaveriaux-Ruff, C; Kieffer, BL; Matifas, A; Nagase, H; Nemoto, T; Nozaki, C1
Hirose, N; Kamei, J; Maruyama, Y; Saitoh, A; Takahashi, K; Yamada, M1
Fujii, H; Nagase, H; Nemoto, T; Oka, J; Saitoh, A; Sugiyama, A; Wada, K; Yamada, M1
Altarifi, AA; Folk, JE; Negus, SS; O'Connell, RH; Rice, KC; Rosenberg, MB1
Nwaneshiudu, CA; Perrine, SA; Schroeder, JA; Sheikh, IS; Unterwald, EM1
Hirose, N; Kamei, J; Murasawa, H; Nakatani, A; Saitoh, A; Takahashi, K; Tatsumi, Y; Yamada, M; Yamaguchi, K1
Broom, DC; Folk, JE; Jutkiewicz, EM; Rice, KC; Traynor, JR; Woods, JH1

Other Studies

9 other study(ies) available for 4-(alpha-(4-allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl)-n,n-diethylbenzamide and Depression

ArticleYear
Up-regulation of BDNF/TrkB signaling by δ opioid receptor agonist SNC80 modulates depressive-like behaviors in chronic restraint-stressed mice.
    European journal of pharmacology, 2023, Mar-05, Volume: 942

    Topics: Animals; Brain-Derived Neurotrophic Factor; Depression; Disease Models, Animal; Hippocampus; Mice; Receptors, Opioid, delta; Signal Transduction; Stress, Psychological; Up-Regulation

2023
Reduced nucleus accumbens enkephalins underlie vulnerability to social defeat stress.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2019, Volume: 44, Issue:11

    Topics: Analgesics, Opioid; Animals; Behavior, Animal; Benzamides; Depression; Disease Models, Animal; Dominance-Subordination; Enkephalins; Mice; Mice, Inbred C57BL; Nucleus Accumbens; Piperazines; Receptors, Opioid, delta; Stress, Psychological

2019
In vivo properties of KNT-127, a novel δ opioid receptor agonist: receptor internalization, antihyperalgesia and antidepressant effects in mice.
    British journal of pharmacology, 2014, Volume: 171, Issue:23

    Topics: Analgesics; Animals; Antidepressive Agents; Behavior, Animal; Benzamides; Depression; Drug Tolerance; Freund's Adjuvant; Hot Temperature; Hyperalgesia; Male; Mice, Inbred C57BL; Mice, Knockout; Morphinans; Motor Activity; Pain; Piperazines; Receptors, Opioid, delta

2014
Gene expression profiling reveals complex changes in the olfactory bulbectomy model of depression after chronic treatment with antidepressants.
    Journal of pharmacological sciences, 2008, Volume: 108, Issue:3

    Topics: Animals; Antidepressive Agents; Behavior, Animal; Benzamides; Cerebral Cortex; Cluster Analysis; Depression; Disease Models, Animal; Gene Expression Profiling; Gene Expression Regulation; Imipramine; Male; Olfactory Bulb; Oligonucleotide Array Sequence Analysis; Piperazines; Rats; Rats, Wistar

2008
The novel δ opioid receptor agonist KNT-127 produces antidepressant-like and antinociceptive effects in mice without producing convulsions.
    Behavioural brain research, 2011, Oct-01, Volume: 223, Issue:2

    Topics: Analgesics; Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Behavior, Animal; Benzamides; Depression; Dopamine Antagonists; Imipramine; Male; Mice; Mice, Inbred ICR; Morphinans; Motor Activity; Naltrexone; Narcotic Antagonists; Pain Measurement; Piperazines; Receptors, Opioid, delta; Seizures; Swimming

2011
Effects of the δ opioid receptor agonist SNC80 on pain-related depression of intracranial self-stimulation (ICSS) in rats.
    The journal of pain, 2012, Volume: 13, Issue:4

    Topics: Analgesics, Opioid; Animals; Benzamides; Depression; Disease Models, Animal; Electrodes, Implanted; Male; Nociceptors; Pain; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Self Stimulation

2012
Withdrawal from chronic administration of cocaine decreases delta opioid receptor signaling and increases anxiety- and depression-like behaviors in the rat.
    Neuropharmacology, 2008, Volume: 54, Issue:2

    Topics: Adenylyl Cyclases; Animals; Anxiety; Behavior, Animal; Benzamides; Cocaine; Data Interpretation, Statistical; Depression; Male; Motor Activity; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Signal Transduction; Substance Withdrawal Syndrome; Swimming

2008
Antidepressant-like effects of the delta-opioid receptor agonist SNC80 ([(+)-4-[(alphaR)-alpha-[(2S,5R)-2,5-dimethyl-4-(2-propenyl)-1-piperazinyl]-(3-methoxyphenyl)methyl]-N,N-diethylbenzamide) in an olfactory bulbectomized rat model.
    Brain research, 2008, May-07, Volume: 1208

    Topics: Analysis of Variance; Animals; Antidepressive Agents; Behavior, Animal; Benzamides; Brain; Depression; Desipramine; Disease Models, Animal; Dose-Response Relationship, Drug; Male; Maze Learning; Olfactory Bulb; Piperazines; Rats; Rats, Wistar; Serotonin; Time Factors; Tryptophan Hydroxylase

2008
Nonpeptidic delta-opioid receptor agonists reduce immobility in the forced swim assay in rats.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2002, Volume: 26, Issue:6

    Topics: Animals; Benzamides; Depression; Dose-Response Relationship, Drug; Immobilization; Male; Motor Activity; Narcotics; Organic Chemicals; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Swimming

2002