5-carboxamidotryptamine has been researched along with Depression in 2 studies
5-carboxamidotryptamine: agonist of 5-HT receptor; structure given in first source
Depression: Depressive states usually of moderate intensity in contrast with MAJOR DEPRESSIVE DISORDER present in neurotic and psychotic disorders.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The novel 5-HT7R antagonist 1-8 exhibited an antidepressant effect at a dose of 25mg/kg in the forced swimming test in mice and showed a U-shaped dose-response curve which typically appears in 5-HT7R antagonists such as SB-269970 and lurasidone." | 1.40 | Novel N-biphenyl-2-ylmethyl 2-methoxyphenylpiperazinylalkanamides as 5-HT7R antagonists for the treatment of depression. ( Cho, H; Choo, H; Choo, IH; Keum, G; Kim, Y; Lee, K; Park, WK; Rhim, H; Tae, J, 2014) |
| " Furthermore, binding studies demonstrate that chronic administration of Fos-inducing agents produces a neuroadaptive downregulation of the 5-HT7 receptor in the hypothalamus." | 1.30 | Effects of antidepressants on 5-HT7 receptor regulation in the rat hypothalamus. ( Eison, AS; Gianutsos, G; Mullins, UL, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kim, Y | 1 |
| Tae, J | 1 |
| Lee, K | 1 |
| Rhim, H | 1 |
| Choo, IH | 1 |
| Cho, H | 1 |
| Park, WK | 1 |
| Keum, G | 1 |
| Choo, H | 1 |
| Mullins, UL | 1 |
| Gianutsos, G | 1 |
| Eison, AS | 1 |
2 other studies available for 5-carboxamidotryptamine and Depression
| Article | Year |
|---|---|
Novel N-biphenyl-2-ylmethyl 2-methoxyphenylpiperazinylalkanamides as 5-HT7R antagonists for the treatment of depression.
Topics: Amides; Animals; Antidepressive Agents; Depression; HEK293 Cells; Humans; Injections, Intraperitonea | 2014 |
Effects of antidepressants on 5-HT7 receptor regulation in the rat hypothalamus.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antidepressive Agents; Circadian Rhythm; Depression | 1999 |