staurosporine aglycone has been researched along with Depression in 10 studies
staurosporine aglycone: metabolite from culture broth of Nocardiopsis sp.; a neurotrophin antag; inhibits BDNF TrkB receptor
Depression: Depressive states usually of moderate intensity in contrast with MAJOR DEPRESSIVE DISORDER present in neurotic and psychotic disorders.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We examined whether oral administration of geranylgeranylacetone (GGA), a known HSP inducer, produced an antidepressant effect in a social defeat stress model of depression in mice." | 3.85 | HSP105 prevents depression-like behavior by increasing hippocampal brain-derived neurotrophic factor levels in mice. ( Hashikawa, N; Hashikawa-Hobara, N; Kayano, M; Morita, Y; Ogawa, T; Tanoue, R; Utaka, Y; Yamaguchi, S; Yamamoto, S; Zamami, Y, 2017) |
| " Despite the recent interest in bicaudal C homolog 1 gene (BICC1) as a target for the treatment of depression, the upstream signaling molecules that regulate BICC1 are unknown, and very few studies have addressed the involvement of BICC1 in the antidepressant-like effects of the selective M1-AchR inhibitor, biperiden." | 3.85 | The antidepressant-like effects of biperiden may involve BDNF/TrkB signaling-mediated BICC1 expression in the hippocampus and prefrontal cortex of mice. ( Cai, X; Geng, J; Li, C; Li, M; Liu, L; Shen, X; Shi, Y; Sun, X; Wang, C; Wang, J; Yu, H; Zhang, Z; Zhou, D, 2017) |
| "Considering that depression is involved in monoamine reduction, this study evaluated the antidepressant-like effects of gypenosides in mice exposed to chronic unpredictable mild stress (CUMS)." | 1.43 | Antidepressant-like effects of standardized gypenosides: involvement of brain-derived neurotrophic factor signaling in hippocampus. ( Chen, SM; Chen, XM; Fang, XY; Li, CF; Li, YC; Liu, Q; Mu, RH; Wang, SS; Yi, LT, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 9 (90.00) | 24.3611 |
| 2020's | 1 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Guan, W | 1 |
| Gu, JH | 1 |
| Ji, CH | 1 |
| Liu, Y | 1 |
| Tang, WQ | 1 |
| Wang, Y | 1 |
| Jiang, B | 1 |
| Zhu, Y | 1 |
| Chao, C | 1 |
| Duan, X | 1 |
| Cheng, X | 1 |
| Liu, P | 1 |
| Su, S | 1 |
| Duan, J | 1 |
| Dong, TT | 1 |
| Tsim, KW | 1 |
| Gong, Y | 1 |
| Yang, Y | 1 |
| Chen, X | 1 |
| Yang, M | 1 |
| Huang, D | 1 |
| Yang, R | 1 |
| Zhou, L | 1 |
| Li, C | 2 |
| Xiong, Q | 1 |
| Xiong, Z | 1 |
| Hashikawa, N | 1 |
| Utaka, Y | 1 |
| Ogawa, T | 1 |
| Tanoue, R | 1 |
| Morita, Y | 1 |
| Yamamoto, S | 1 |
| Yamaguchi, S | 1 |
| Kayano, M | 1 |
| Zamami, Y | 1 |
| Hashikawa-Hobara, N | 1 |
| Sartim, AG | 1 |
| Sales, AJ | 1 |
| Guimarães, FS | 1 |
| Joca, SR | 1 |
| Takasaki, I | 1 |
| Oose, K | 1 |
| Otaki, Y | 1 |
| Ihara, D | 1 |
| Fukuchi, M | 1 |
| Tabuchi, A | 1 |
| Tsuneki, H | 1 |
| Tabuchi, Y | 1 |
| Kondo, T | 1 |
| Saitoh, A | 1 |
| Yamada, M | 1 |
| Tsuda, M | 1 |
| Mu, RH | 1 |
| Fang, XY | 1 |
| Wang, SS | 1 |
| Li, CF | 1 |
| Chen, SM | 1 |
| Chen, XM | 1 |
| Liu, Q | 1 |
| Li, YC | 1 |
| Yi, LT | 1 |
| Zhang, MW | 1 |
| Zhang, SF | 1 |
| Li, ZH | 1 |
| Han, F | 1 |
| Zhou, D | 1 |
| Zhang, Z | 1 |
| Liu, L | 1 |
| Li, M | 1 |
| Yu, H | 1 |
| Cai, X | 1 |
| Sun, X | 1 |
| Shen, X | 1 |
| Wang, J | 1 |
| Geng, J | 1 |
| Wang, C | 1 |
| Shi, Y | 1 |
| Yamada, N | 1 |
| Katsuura, G | 1 |
| Ochi, Y | 1 |
| Ebihara, K | 1 |
| Kusakabe, T | 1 |
| Hosoda, K | 1 |
| Nakao, K | 1 |
10 other studies available for staurosporine aglycone and Depression
| Article | Year |
|---|---|
Xanthoceraside administration produces significant antidepressant effects in mice through activation of the hippocampal BDNF signaling pathway.
Topics: Animals; Behavior, Animal; Brain-Derived Neurotrophic Factor; Carbazoles; Depression; Disease Models | 2021 |
Kai-Xin-San series formulae alleviate depressive-like behaviors on chronic mild stressed mice via regulating neurotrophic factor system on hippocampus.
Topics: Animals; Antidepressive Agents; Brain-Derived Neurotrophic Factor; Carbazoles; Depression; Disease M | 2017 |
Hyperoside protects against chronic mild stress-induced learning and memory deficits.
Topics: Animals; Brain-Derived Neurotrophic Factor; Carbazoles; Chronic Disease; Cognition; Corticosterone; | 2017 |
HSP105 prevents depression-like behavior by increasing hippocampal brain-derived neurotrophic factor levels in mice.
Topics: Animals; Behavior, Animal; Brain-Derived Neurotrophic Factor; Carbazoles; Cell Line; Depression; Dit | 2017 |
Hippocampal mammalian target of rapamycin is implicated in stress-coping behavior induced by cannabidiol in the forced swim test.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Brain-Derived Neurotrophic Factor; Cannabidiol; Ca | 2018 |
Type II pyrethroid deltamethrin produces antidepressant-like effects in mice.
Topics: Animals; Antidepressive Agents; Brain-Derived Neurotrophic Factor; Carbazoles; Depression; Disease M | 2013 |
Antidepressant-like effects of standardized gypenosides: involvement of brain-derived neurotrophic factor signaling in hippocampus.
Topics: Animals; Antidepressive Agents; Brain-Derived Neurotrophic Factor; Carbazoles; Depression; Disease M | 2016 |
7,8-Dihydroxyflavone reverses the depressive symptoms in mouse chronic mild stress.
Topics: Animals; Antidepressive Agents; Brain-Derived Neurotrophic Factor; Carbazoles; Depression; Disks Lar | 2016 |
The antidepressant-like effects of biperiden may involve BDNF/TrkB signaling-mediated BICC1 expression in the hippocampus and prefrontal cortex of mice.
Topics: Animals; Antidepressive Agents; Biperiden; Brain-Derived Neurotrophic Factor; Carbazoles; Depression | 2017 |
Impaired CNS leptin action is implicated in depression associated with obesity.
Topics: Animals; Behavior, Animal; Brain Mapping; Brain-Derived Neurotrophic Factor; Carbazoles; Depression; | 2011 |