Page last updated: 2024-10-17

2-aminoadipic acid and Depression

2-aminoadipic acid has been researched along with Depression in 5 studies

2-Aminoadipic Acid: A metabolite in the principal biochemical pathway of lysine. It antagonizes neuroexcitatory activity modulated by the glutamate receptor, N-METHYL-D-ASPARTATE; (NMDA).
2-aminoadipic acid : An alpha-amino acid that is adipic acid bearing a single amino substituent at position 2. An intermediate in the formation of lysine.

Depression: Depressive states usually of moderate intensity in contrast with MAJOR DEPRESSIVE DISORDER present in neurotic and psychotic disorders.

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's3 (60.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Domin, H2
Konieczny, J1
Cieślik, P1
Pochwat, B1
Wyska, E1
Szafarz, M1
Lenda, T1
Biała, D1
Gąsior, Ł1
Śmiałowska, M2
Szewczyk, B2
David, J1
Gormley, S1
McIntosh, AL1
Kebede, V1
Thuery, G1
Varidaki, A1
Coffey, ET1
Harkin, A1
Funatsu, S1
Kondoh, T1
Kawase, T1
Ikeda, H1
Nagasawa, M1
Denbow, DM1
Furuse, M1
Woźniak, M1
Wawrzak-Wleciał, A1
Banasr, M1
Duman, RS1

Other Studies

5 other studies available for 2-aminoadipic acid and Depression

ArticleYear
The antidepressant-like and glioprotective effects of the Y2 receptor antagonist SF-11 in the astroglial degeneration model of depression in rats: Involvement of glutamatergic inhibition.
    Behavioural brain research, 2024, 02-04, Volume: 457

    Topics: 2-Aminoadipic Acid; Animals; Antidepressive Agents; Astrocytes; Depression; Gliotoxin; Prefrontal Co

2024
L-alpha-amino adipic acid provokes depression-like behaviour and a stress related increase in dendritic spine density in the pre-limbic cortex and hippocampus in rodents.
    Behavioural brain research, 2019, 04-19, Volume: 362

    Topics: 2-Aminoadipic Acid; Animals; Antidepressive Agents; Astrocytes; Behavior, Animal; Dendritic Spines;

2019
Long-term consumption of dried bonito dashi (a traditional Japanese fish stock) reduces anxiety and modifies central amino acid levels in rats.
    Nutritional neuroscience, 2015, Volume: 18, Issue:6

    Topics: 2-Aminoadipic Acid; Amino Acids; Animals; Anserine; Anxiety; Asparagine; Behavior, Animal; Cerebellu

2015
Antidepressant-like effect of the mGluR5 antagonist MTEP in an astroglial degeneration model of depression.
    Behavioural brain research, 2014, Oct-15, Volume: 273

    Topics: 2-Aminoadipic Acid; Animals; Antidepressive Agents; Astrocytes; Depression; Disease Models, Animal;

2014
Glial loss in the prefrontal cortex is sufficient to induce depressive-like behaviors.
    Biological psychiatry, 2008, Nov-15, Volume: 64, Issue:10

    Topics: 2-Aminoadipic Acid; Analysis of Variance; Animals; Avoidance Learning; Behavior, Animal; Cell Death;

2008