methotrexate has been researched along with Depression in 29 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (6.90) | 18.7374 |
| 1990's | 5 (17.24) | 18.2507 |
| 2000's | 7 (24.14) | 29.6817 |
| 2010's | 9 (31.03) | 24.3611 |
| 2020's | 6 (20.69) | 2.80 |
| Authors | Studies |
|---|---|
| Amada, N; Futamura, T; Kakumoto, Y; Maeda, K | 1 |
| Aslanlar, DA; Nurullahoglu Atalik, KE; Oz, M; Vişneci, EF | 1 |
| Andrejkovics, M; Baráth, Z; Bereczki, D; Domján, A; Fazekas, K; Flórián, Á; Hodosi, K; Kardos, Z; Kerekes, G; Kostyál, L; Lukács, K; Miksi, Á; Oláh, C; Péntek, M; Sas, A; Sepsi, M; Szarka, E; Szekanecz, Z; Tamási, L; Valikovics, A | 1 |
| Hammami, MB; Mahadevan, U | 1 |
| Barton, JL; England, BR; Hochberg, MC; Mikuls, TR; Rathbun, AM; Ryan, AS; Shardell, MD | 1 |
| Stiebitz, S; Strickler, M; von Streng, T | 1 |
| Fagerli, KM; Hammer, HB; Haugeberg, G; Kalstad, S; Kristianslund, EK; Krøll, F; Kvien, TK; Lie, E; Michelsen, B; Rødevand, E; Sexton, J; Wierød, A | 1 |
| de Jong, P; Hazes, J; Kuijper, TM; Luime, JJ; Tchetverikov, I; van der Lubbe, P; van Zeben, D; Weel, A; Xiong, H | 1 |
| Aftab, MT; Hassali, MA; Naqvi, AA | 1 |
| Beaulieu, P; Bertout, L; Boulet-Craig, A; Drouin, S; Hudson, MM; Krajinovic, M; Krull, KR; Laniel, J; Laverdière, C; Lippé, S; Petrykey, K; Rezgui, A; Robaey, P; Sapkota, Y; Sinnett, D; St-Onge, P; Sultan, S; Yasui, Y | 1 |
| Nardi, AE; Ornelas, AC; Pinho de Oliveira Ribeiro, N; Pinho de Oliveira, CM; Rafael de Mello Schier, A; Silva, AC | 1 |
| Allaart, CF; Giltay, EJ; Heimans, L; Huizinga, TW; Ronday, HK; Steup-Beekman, GM; van der Mast, RC; van Oosterhout, M; Visser, K; Wevers-de Boer, KV | 1 |
| Freundlich, B; Kekow, J; Khandker, R; Melin, J; Moots, R; Singh, A | 1 |
| Hajjaj-Hassouni, N; Ibn Yacoub, Y; Laatiris, A; Rostom, S | 1 |
| Jang, S; Kim, J; Kim, JC; Kim, JS; Kim, SH; Moon, C; Shin, T; Wang, H; Yang, M | 1 |
| Berglund, G; Bolund, C; Fornander, T; Nystedt, M; Rutqvist, LE | 1 |
| Duman, RS | 1 |
| Abu-Saad, HH; Candel, MJ; Courtens, AM; de Jong, N; Schouten, HC | 1 |
| Beutner, KR; Bhushan, R; Elmets, CA; Feldman, SR; Gordon, KB; Gottlieb, A; Koo, JY; Korman, NJ; Lebwohl, M; Leonardi, CL; Menter, A; Van Voorhees, AS | 1 |
| Bleehen, NM; Girling, DJ; Machin, D; Stephens, RJ | 1 |
| Ankum, WM; Bossuyt, PM; Hajenius, PJ; Nieuwkerk, PT; Van der Veen, F; Wijker, W | 1 |
| Fifield, J; McQuillan, J; Reisine, S; Tennen, H | 1 |
| Boogerd, W; Bruning, PF; Lindeboom, J; Muller, MJ; Schagen, SB; van Dam, FS | 1 |
| Bredart, A; Colleoni, M; Goldhirsch, A; Mandala, M; Peruzzotti, G; Robertson, C | 1 |
| Farquhar, CM; Gudex, G; Petrie, KJ; Sowter, MC | 1 |
| Blakemore, KJ; Duhl, AJ; Escallon, CS; Nguyen, C | 1 |
| Drigan, R; Gelber, RD; Spirito, A | 1 |
| Alarcón, GS; Blake, DJ; Brown, S; Koplan, A; Maisiak, R | 1 |
| Appelbaum, FR; Banaji, M; Bensinger, WI; Buckner, CD; Clift, RA; Deeg, HJ; Flournoy, N; Kennedy, MS; Storb, R; Thomas, ED | 1 |
3 review(s) available for methotrexate and Depression
| Article | Year |
|---|---|
Men With Inflammatory Bowel Disease: Sexual Function, Fertility, Medication Safety, and Prostate Cancer.
Topics: Depression; Gastrointestinal Agents; Humans; Infertility, Male; Inflammatory Bowel Diseases; Male; Methotrexate; Prostatic Neoplasms; Risk Factors; Sexual Dysfunction, Physiological; Sulfasalazine | 2020 |
Epidemiology of rheumatoid arthritis, clinical aspects and socio-economic determinants in Pakistani patients: A systematic review and meta-analysis.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Bone Diseases, Metabolic; Cardiovascular Diseases; Comorbidity; Cost of Illness; Depression; Depressive Disorder; Fibromyalgia; Methotrexate; Osteoporosis; Pakistan; Prevalence; Risk Factors; Social Class | 2019 |
Depression: a case of neuronal life and death?
Topics: Animals; Antidepressive Agents; Antineoplastic Combined Chemotherapy Protocols; Cell Death; Cell Division; Depression; Etoposide; Humans; Ifosfamide; Limbic System; Methotrexate; Models, Neurological; Models, Psychological; Mood Disorders; Neurons; Stress, Physiological | 2004 |
8 trial(s) available for methotrexate and Depression
| Article | Year |
|---|---|
Effects of psychosocial factors on monitoring treatment effect in newly diagnosed rheumatoid arthritis patients over time: response data from the tREACH study.
Topics: Antirheumatic Agents; Anxiety; Arthritis, Rheumatoid; Depression; Disease Progression; Drug Therapy, Combination; Female; Follow-Up Studies; Glucocorticoids; Humans; Male; Methotrexate; Middle Aged; Monitoring, Physiologic; Severity of Illness Index; Sulfasalazine; Time Factors; Treatment Outcome | 2018 |
The relationship between disease activity and depressive symptoms severity and optimism--results from the IMPROVED study.
Topics: Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Attitude; Depression; Female; Humans; Inflammation; Male; Methotrexate; Middle Aged; Prednisone; Regression Analysis; Remission Induction; Severity of Illness Index; Surveys and Questionnaires | 2013 |
Side effects of adjuvant endocrine treatment in premenopausal breast cancer patients: a prospective randomized study.
Topics: Adult; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Anxiety; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Depression; Female; Fluorouracil; Goserelin; Health Status; Humans; Methotrexate; Middle Aged; Premenopause; Severity of Illness Index; Tamoxifen; Treatment Outcome | 2003 |
A randomised trial of three or six courses of etoposide cyclophosphamide methotrexate and vincristine or six courses of etoposide and ifosfamide in small cell lung cancer (SCLC). II: Quality of life. Medical Research Council Lung Cancer Working Party.
Topics: Adult; Aged; Anorexia; Antineoplastic Combined Chemotherapy Protocols; Anxiety; Carcinoma, Small Cell; Cyclophosphamide; Depression; Dose-Response Relationship, Drug; Drug Administration Schedule; Etoposide; Female; Humans; Ifosfamide; Infusions, Intravenous; Lung Neoplasms; Male; Medical Records; Methotrexate; Middle Aged; Nausea; Palliative Care; Patient Compliance; Quality of Life; Self-Assessment; Vincristine; Vomiting | 1993 |
Systemic methotrexate therapy versus laparoscopic salpingostomy in patients with tubal pregnancy. Part I. Impact on patients' health-related quality of life.
Topics: Adaptation, Psychological; Adult; Anxiety; Depression; Female; Humans; Injections, Intramuscular; Methotrexate; Pregnancy; Pregnancy, Tubal; Quality of Life; Salpingostomy; Surveys and Questionnaires; Treatment Outcome | 1998 |
Cognitive deficits after postoperative adjuvant chemotherapy for breast carcinoma.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Attention; Breast Neoplasms; Chemotherapy, Adjuvant; Cognition Disorders; Cyclophosphamide; Depression; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neuropsychological Tests; Quality of Life; Socioeconomic Factors | 1999 |
A randomised trial comparing single dose systemic methotrexate and laparoscopic surgery for the treatment of unruptured tubal pregnancy.
Topics: Abortifacient Agents, Nonsteroidal; Adult; Anxiety; Chorionic Gonadotropin; Depression; Female; Health Status; Humans; Hysterosalpingography; Laparoscopy; Methotrexate; Pregnancy; Pregnancy, Tubal; Prospective Studies; Surveys and Questionnaires; Treatment Outcome | 2001 |
Cyclosporine as prophylaxis for graft-versus-host disease: a randomized study in patients undergoing marrow transplantation for acute nonlymphoblastic leukemia.
Topics: Acute Disease; Adolescent; Adult; Bacterial Infections; Bone Marrow Transplantation; Cyclosporins; Depression; Graft vs Host Disease; Humans; Hypertension; Kidney Diseases; Length of Stay; Leukemia; Liver Diseases; Methotrexate; Middle Aged; Mycoses; Pulmonary Fibrosis; Random Allocation | 1985 |
18 other study(ies) available for methotrexate and Depression
| Article | Year |
|---|---|
Prenatal methotrexate injection increases behaviors possibly associated with depression and/or autism in rat offspring; A new animal model for mental disorder, based on folate metabolism deficit during pregnancy.
Topics: Animals; Autistic Disorder; Behavior, Animal; Depression; Disease Models, Animal; DNA; Female; Folic Acid; Humans; Mental Disorders; Methotrexate; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Vitamins | 2022 |
N-acetylcysteine ameliorates chemotherapy-induced impaired anxiety and depression-like behaviors by regulating inflammation, oxidative and cholinergic status, and BDNF release.
Topics: Acetylcholinesterase; Acetylcysteine; Animals; Antineoplastic Agents; Antioxidants; Anxiety; Brain-Derived Neurotrophic Factor; Cholinergic Agents; Depression; Humans; Inflammation; Male; Methotrexate; Oxidative Stress; Rats; Rats, Wistar | 2024 |
Assessment of cognitive function in female rheumatoid arthritis patients: associations with cerebrovascular pathology, depression and anxiety.
Topics: Aged; Antirheumatic Agents; Anxiety; Arthritis, Rheumatoid; Biological Products; Carotid Intima-Media Thickness; Case-Control Studies; Cognition; Cognitive Dysfunction; Cross-Sectional Studies; Depression; Female; Humans; Mental Status and Dementia Tests; Methotrexate; Middle Aged; Middle Cerebral Artery | 2020 |
Relationship Between Depression and Disease Activity in United States Veterans With Early Rheumatoid Arthritis Receiving Methotrexate.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Depression; Drug Therapy, Combination; Humans; Male; Methotrexate; Severity of Illness Index; Treatment Outcome; United States; Veterans | 2021 |
Delayed diagnosis of rheumatoid arthritis in an elderly patient presenting with weakness and desolation.
Topics: Aged, 80 and over; Antirheumatic Agents; Arthritis, Rheumatoid; Biomarkers; Delayed Diagnosis; Depression; Diagnosis, Differential; Diagnostic Imaging; Glucocorticoids; Humans; Male; Methotrexate; Muscle Weakness | 2021 |
Do depression and anxiety reduce the likelihood of remission in rheumatoid arthritis and psoriatic arthritis? Data from the prospective multicentre NOR-DMARD study.
Topics: Adult; Aged; Antirheumatic Agents; Anxiety; Arthralgia; Arthritis, Psoriatic; Arthritis, Rheumatoid; Depression; Female; Follow-Up Studies; Humans; Logistic Models; Male; Methotrexate; Middle Aged; Predictive Value of Tests; Prospective Studies; Remission Induction; Severity of Illness Index; Treatment Outcome; Tumor Necrosis Factor-alpha | 2017 |
Influence of genetic factors on long-term treatment related neurocognitive complications, and on anxiety and depression in survivors of childhood acute lymphoblastic leukemia: The Petale study.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adolescent; Adult; Antimetabolites, Antineoplastic; Anxiety; Calcium Channels, L-Type; Child; Child, Preschool; Cohort Studies; Depression; Female; Humans; Infant; Liver-Specific Organic Anion Transporter 1; Long-Term Care; Male; Methotrexate; Neurocognitive Disorders; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Survivors; Young Adult | 2019 |
Anxiety, depression and suicidal ideation in patients with rheumatoid arthritis in use of methotrexate, hydroxychloroquine, leflunomide and biological drugs.
Topics: Adult; Aged; Antirheumatic Agents; Anxiety; Arthritis, Rheumatoid; Comorbidity; Depression; Female; Humans; Hydroxychloroquine; Isoxazoles; Leflunomide; Male; Methotrexate; Middle Aged; Psychiatric Status Rating Scales; Suicidal Ideation | 2013 |
Improvements in patient-reported outcomes, symptoms of depression and anxiety, and their association with clinical remission among patients with moderate-to-severe active early rheumatoid arthritis.
Topics: Adult; Antirheumatic Agents; Anxiety; Arthritis, Rheumatoid; Depression; Drug Therapy, Combination; Etanercept; Health Status; Humans; Immunoglobulin G; Logistic Models; Methotrexate; Middle Aged; Psychiatric Status Rating Scales; Randomized Controlled Trials as Topic; Receptors, Tumor Necrosis Factor; Remission Induction; Self Report; Severity of Illness Index; Time Factors; Treatment Outcome | 2011 |
Primary Sjögren's syndrome in Moroccan patients: characteristics, fatigue and quality of life.
Topics: Adult; Aged; Antidepressive Agents; Antirheumatic Agents; Cross-Sectional Studies; Depression; Disability Evaluation; Fatigue; Female; Humans; Male; Methotrexate; Middle Aged; Morocco; Prevalence; Quality of Life; Retrospective Studies; Severity of Illness Index; Sjogren's Syndrome; Surveys and Questionnaires; Treatment Outcome | 2012 |
Acute treatment with methotrexate induces hippocampal dysfunction in a mouse model of breast cancer.
Topics: Animals; Antimetabolites, Antineoplastic; Depression; Female; Hippocampus; Mammary Neoplasms, Experimental; Memory Disorders; Methotrexate; Mice; Mice, Inbred C3H; Tumor Cells, Cultured | 2012 |
Course of mental fatigue and motivation in breast cancer patients receiving adjuvant chemotherapy.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cognition Disorders; Cyclophosphamide; Depression; Fatigue; Female; Fluorouracil; Humans; Mastectomy; Mastectomy, Segmental; Methotrexate; Middle Aged; Motivation; Prospective Studies; Quality of Life | 2005 |
Guidelines of care for the management of psoriasis and psoriatic arthritis: Section 1. Overview of psoriasis and guidelines of care for the treatment of psoriasis with biologics.
Topics: Acitretin; Alefacept; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Arthritis, Psoriatic; Biological Products; Cardiovascular Diseases; Cyclosporine; Depression; Etanercept; Humans; Immunoglobulin G; Interleukin-12; Interleukin-23; Lymphoma; Metabolic Syndrome; Methotrexate; Obesity; Psoriasis; PUVA Therapy; Receptors, Tumor Necrosis Factor; Recombinant Fusion Proteins; Smoking; Tumor Necrosis Factor-alpha | 2008 |
Depression and the long-term risk of pain, fatigue, and disability in patients with rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Depression; Disability Evaluation; Fatigue; Humans; Methotrexate; Pain; Prednisone; Risk Factors; Severity of Illness Index; Time Factors | 1998 |
Depression and degree of acceptance of adjuvant cytotoxic drugs.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Case-Control Studies; Chemotherapy, Adjuvant; Cyclophosphamide; Depression; Drug Administration Schedule; Female; Fluorouracil; Humans; Logistic Models; Methotrexate; Middle Aged; Patient Acceptance of Health Care; Retrospective Studies | 2000 |
Multiple anomalies in a fetus exposed to low-dose methotrexate in the first trimester.
Topics: Abnormalities, Multiple; Adolescent; Bone and Bones; Craniofacial Abnormalities; Depression; Digestive System; Digestive System Abnormalities; Female; Fetal Death; Heart Defects, Congenital; Humans; Infant, Newborn; Methotrexate; Pregnancy; Pregnancy Complications; Pregnancy Trimester, First; Psoriasis; Sertraline; Ultrasonography, Prenatal | 2002 |
Behavioral effects of corticosteroids in children with acute lymphoblastic leukemia.
Topics: Age Factors; Analysis of Variance; Attention; Child; Child Behavior; Child, Preschool; Cytarabine; Depression; Doxorubicin; Drug Interactions; Emotions; Female; Humans; Infant; Interpersonal Relations; Male; Mercaptopurine; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Prospective Studies; Sex Factors; Sleep; Vincristine | 1992 |
Sexual dysfunction among patients with arthritis.
Topics: Arthritis; Depression; Erectile Dysfunction; Female; Happiness; Humans; Male; Marriage; Methotrexate; Penile Erection; Sex Factors; Sexual Dysfunction, Physiological; Spasm; Vaginal Diseases | 1988 |