trigonelline has been researched along with Depression in 2 studies
trigonelline: in hydra among other organisms; RN given refers to hydroxide inner salt; structure
N-methylnicotinic acid : A pyridinium ion consisting of nicotinic acid having a methyl substituent on the pyridine nitrogen.
N-methylnicotinate : An iminium betaine that is the conjugate base of N-methylnicotinic acid, arising from deprotonation of the carboxy group.
Depression: Depressive states usually of moderate intensity in contrast with MAJOR DEPRESSIVE DISORDER present in neurotic and psychotic disorders.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Trigonelline (TRG) is a pyridine alkaloid that has various pharmacological effects including hypoglycemic, neuroprotective and memory-improving properties." | 1.56 | Trigonelline through the Attenuation of Oxidative Stress Exerts Antidepressant- and Anxiolytic-Like Effects in a Mouse Model of Maternal Separation Stress. ( Amini-Khoei, H; Bijad, E; Habibian Dehkordi, S; Lorigooini, Z; Sadeghi Dehsahraei, K, 2020) |
| "Trigonelline is an alkaloid with neuroprotective activity." | 1.56 | Possible Involvement of N-methyl-D-aspartate Receptor (NMDA-R) in the Antidepressant- like Effect of Trigonelline in Male Mice. ( Amini-Khoei, H; Anjomshoa, M; Bagheri, E; Boroujeni, SN; Lorigooini, Z, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lorigooini, Z | 2 |
| Sadeghi Dehsahraei, K | 1 |
| Bijad, E | 1 |
| Habibian Dehkordi, S | 1 |
| Amini-Khoei, H | 2 |
| Anjomshoa, M | 1 |
| Boroujeni, SN | 1 |
| Bagheri, E | 1 |
2 other studies available for trigonelline and Depression
| Article | Year |
|---|---|
Trigonelline through the Attenuation of Oxidative Stress Exerts Antidepressant- and Anxiolytic-Like Effects in a Mouse Model of Maternal Separation Stress.
Topics: Alkaloids; Animals; Anti-Anxiety Agents; Antidepressive Agents; Antioxidants; Anxiety; Behavior, Ani | 2020 |
Possible Involvement of N-methyl-D-aspartate Receptor (NMDA-R) in the Antidepressant- like Effect of Trigonelline in Male Mice.
Topics: Alkaloids; Animals; Antidepressive Agents; Depression; Male; Mice; N-Methylaspartate; Receptors, N-M | 2020 |