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meprobamate and Depression

meprobamate has been researched along with Depression in 50 studies

Meprobamate: A carbamate with hypnotic, sedative, and some muscle relaxant properties, although in therapeutic doses reduction of anxiety rather than a direct effect may be responsible for muscle relaxation. Meprobamate has been reported to have anticonvulsant actions against petit mal seizures, but not against grand mal seizures (which may be exacerbated). It is used in the treatment of ANXIETY DISORDERS, and also for the short-term management of INSOMNIA but has largely been superseded by the BENZODIAZEPINES. (From Martindale, The Extra Pharmacopoeia, 30th ed, p603)

Depression: Depressive states usually of moderate intensity in contrast with MAJOR DEPRESSIVE DISORDER present in neurotic and psychotic disorders.

Research Excerpts

ExcerptRelevanceReference
"Phenazepam given to rats in a daily dose of 2 mg/kg intraperitoneally for a long (30 days) time ceased to produce the sedative effect, and discontinuation of the medication led to development of the so-called "recoil syndrome" characterized by general depression and disturbances of the conditioned-reflex activity."3.66[Experimental study of the "'rebound syndrome" following discontinuation of prolonged phenazepam administration and possibilities for preventing it]. ( Garibova, TL; Voronina, TA, 1981)

Research

Studies (50)

TimeframeStudies, this research(%)All Research%
pre-199050 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
ALEXANDER, L2
THIERS, H1
OLIVIER, L1
COLOMB, D1
FAYOLLE, J1
MOULIN, J1
PARIGI, S1
BIAGIOTTI, F1
BELL, JL1
TAUBER, H1
SANTY, A1
PULITO, F1
RUCHWARGER, A1
GORDON, PE2
WILSON, IC1
BROSSEAU, M1
KEARNEY, TR1
ACHTE, KA1
APPLEBY, B1
RICKELS, K6
WARD, CH1
SCHUT, L1
VILKIN, MI1
BOJANOVSKY, J1
CHLOUPKOVA, K1
CHARRIOT, G1
LAMBERT, PA1
KARLSSON, KW1
LEVIT, VG1
SMULEVICH, AB1
POLLACK, B1
MEDUNA, LJ1
BATTERMAN, RC1
FELLNER, CH1
LANDMAN, ME1
SETTEL, E1
Voronina, TA1
Garibova, TL1
Lader, M1
Azcarate, CL1
Kamen, S1
Zung, WW1
Mendels, J1
Hawkins, DR1
Boysen, KH1
Hollister, LE1
Guelfi, JD1
Olivier-Martin, R1
Anton, AH1
Lipman, RS3
Uhlenhuth, EH2
Covi, L3
Downing, RW1
Kellner, R1
Wygant, EG1
Gayral, LF1
Escande, M1
Raab, E1
DeSilverio, R1
Etemad, B1
Derogatis, LR2
Margat, P1
Broussot, T1
Pouly, JP1
Pearson, MM1
Little, RB1
Rickles, K1

Reviews

4 reviews available for meprobamate and Depression

ArticleYear
Minor tranquilizers in the treatment of aggression.
    The Journal of nervous and mental disease, 1975, Volume: 160, Issue:2-1

    Topics: Aggression; Animals; Anti-Anxiety Agents; Anxiety; Chlordiazepoxide; Depression; Diazepam; Epilepsy;

1975
The pharmacology of disordered sleep: a laboratory approach.
    International psychiatry clinics, 1970, Volume: 7, Issue:2

    Topics: Amitriptyline; Anxiety; Arousal; Barbiturates; Brain; Cerebral Cortex; Depression; Desipramine; Huma

1970
Drug use in outpatient treatment.
    The American journal of psychiatry, 1968, Volume: 124, Issue:8

    Topics: Anxiety; Barbiturates; Chlordiazepoxide; Depression; Diazepam; Educational Status; Humans; Meprobama

1968
Psychopharmacology: a review.
    International anesthesiology clinics, 1968,Spring, Volume: 6, Issue:1

    Topics: Amitriptyline; Antidepressive Agents; Anxiety; Butyrophenones; Chlordiazepoxide; Chlorprothixene; De

1968

Trials

11 trials available for meprobamate and Depression

ArticleYear
[Results of a clinical and ambulatory comparative study involving two tranquilizing drug compounds].
    Wiener medizinische Wochenschrift (1946), 1974, Jul-27, Volume: 124, Issue:30

    Topics: Adult; Ambulatory Care; Depression; Drug Combinations; Drug Evaluation; Ethanol; Female; Humans; Mal

1974
[Prudent use of drugs against anxiety].
    Der Internist, 1973, Volume: 14, Issue:4

    Topics: Anxiety; Chemical Phenomena; Chemistry; Depression; Diazepam; Evaluation Studies as Topic; Humans; H

1973
Meprobamate combined with benactyzine.
    The Practitioner, 1969, Volume: 202, Issue:211

    Topics: Adolescent; Adult; Aged; Anxiety Disorders; Benactyzine; Child; Clinical Trials as Topic; Depression

1969
Medication attitudes and drug response.
    Diseases of the nervous system, 1969, Volume: 30, Issue:7

    Topics: Anorexia Nervosa; Anxiety; Atropine; Attitude; Attitude of Health Personnel; Clinical Trials as Topi

1969
Patient personality and demographic factors as predictors of early response to psychotropic drug treatment.
    Comprehensive psychiatry, 1970, Volume: 11, Issue:6

    Topics: Adult; Age Factors; Anxiety Disorders; Attitude to Health; Chlordiazepoxide; Clinical Trials as Topi

1970
Psychopharmacology.
    Acta psychiatrica Scandinavica. Supplementum, 1970, Volume: 217

    Topics: Alcoholism; Anxiety; Brain Damage, Chronic; Chronic Disease; Clinical Trials as Topic; Depression; E

1970
1. Improvement criteria in drug trials with neurotic patients.
    Psychological medicine, 1971, Volume: 1, Issue:5

    Topics: Amobarbital; Chlordiazepoxide; Clinical Trials as Topic; Depression; Evaluation Studies as Topic; Hu

1971
Relief of depression in patients with chronic diseases.
    Current therapeutic research, clinical and experimental, 1966, Volume: 8, Issue:8

    Topics: Adult; Aged; Benactyzine; Chronic Disease; Clinical Trials as Topic; Depression; Humans; Male; Mepro

1966
Triavil and Etrafon.
    The Medical letter on drugs and therapeutics, 1966, Feb-25, Volume: 8, Issue:4

    Topics: Amitriptyline; Chlordiazepoxide; Clinical Trials as Topic; Depression; Diazepam; Female; Humans; Mep

1966
Meprobamate and benactyzine (Deprol) in the treatment of depression in general practice. (A controlled study).
    Diseases of the nervous system, 1967, Volume: 28, Issue:4

    Topics: Adolescent; Adult; Aged; Anxiety; Benactyzine; Clinical Trials as Topic; Depression; Female; Humans;

1967
Drug treatment in depression. Antidepressant or tranquilizer?
    JAMA, 1967, Aug-28, Volume: 201, Issue:9

    Topics: Adult; Antidepressive Agents; Anxiety Disorders; Clinical Trials as Topic; Depression; Female; Human

1967

Other Studies

35 other studies available for meprobamate and Depression

ArticleYear
Chemotherapy of depression; use of meprobamate combined with benactyzine (2-diethylaminoethyl benzilate) hydrochloride.
    Journal of the American Medical Association, 1958, Mar-01, Volume: 166, Issue:9

    Topics: Benactyzine; Benzilates; Depression; Depressive Disorder; Humans; Meprobamate; Salts; Tranquilizing

1958
[Importance of meprobamate in dermatology].
    Lyon medical, 1958, Jan-19, Volume: 90, Issue:3

    Topics: Anxiety; Anxiety Disorders; Depression; Depressive Disorder; Dermatology; Humans; Meprobamate; Neuro

1958
[Mental tests (Rorschach, TAT & Toulose-Pieron) and administration of meprobamate].
    Rivista di patologia nervosa e mentale, 1957, Volume: 78, Issue:3

    Topics: Depression; Depressive Disorder; Humans; Intelligence Tests; Meprobamate; Neurotic Disorders; Psycho

1957
Meprobamate combined with 2-diethyl-aminoethyl benzilate hydrochloride (benactyzine).
    Diseases of the nervous system, 1958, Volume: 19, Issue:7, Part 2

    Topics: Benactyzine; Benzilates; Depression; Depressive Disorder; Humans; Meprobamate; Parasympatholytics; S

1958
Treatment of depressive states in office practice.
    Diseases of the nervous system, 1959, Volume: 20, Issue:6

    Topics: Depression; Depressive Disorder; Humans; Meprobamate; Parasympatholytics; Tranquilizing Agents

1959
Use of deprol (meprobamate combined with benactyzine hydrochloride) in the office treatment of depression.
    The Medical annals of the District of Columbia, 1959, Volume: 28, Issue:8

    Topics: Benactyzine; Depression; Depressive Disorder; Meprobamate; Parasympatholytics; Tranquilizing Agents

1959
Deprol in the treatment of depression.
    Diseases of the nervous system, 1960, Volume: 21

    Topics: Depression; Depressive Disorder; Meprobamate; Parasympatholytics

1960
STATUS EPILEPTICUS ASSOCIATED WITH WITHDRAWAL FROM DEPROL (MEPROBAMATE AND BENACTYZINE).
    The American journal of psychiatry, 1963, Volume: 120

    Topics: Benactyzine; Conduct Disorder; Depression; Depressive Disorder; Epilepsy; Humans; Meprobamate; Statu

1963
[THE ANTIDEPRESSANTS. DRUG INCOMPATIBILITY].
    L'union medicale du Canada, 1963, Volume: 92

    Topics: Antidepressive Agents; Chlordiazepoxide; Chlorpromazine; Depression; Drug Incompatibility; Imipramin

1963
SUPPORTIVE PSYCHOTHERAPY IN A MEDICAL CLINIC.
    Diseases of the nervous system, 1963, Volume: 24

    Topics: Chlordiazepoxide; Depression; Hospitals, Psychiatric; Humans; Mental Disorders; Meprobamate; Neuroti

1963
[THE PROBLEM OF SUICIDE].
    Nordisk psykiatrisk tidsskrift. Nordic journal of psychiatry, 1963, Volume: 17

    Topics: Alcoholism; Antidepressive Agents; Chlordiazepoxide; Counseling; Depression; Depressive Disorder; Fi

1963
A NEW TREATMENT OF PREMENSTRUAL TENSION.
    The Practitioner, 1964, Volume: 192

    Topics: Bendroflumethiazide; Chlorothiazide; Depression; Depressive Disorder; Female; Humans; Meprobamate; P

1964
DIFFERENT POPULATIONS, DIFFERENT DRUG RESPONSES. A COMPARATIVE STUDY OF TWO ANTI-DEPRESSANTS, EACH USED IN TWO DIFFERENT PATIENT GROUPS.
    The American journal of the medical sciences, 1964, Volume: 247

    Topics: Antidepressive Agents; Benactyzine; Depression; Humans; Imipramine; Meprobamate; Pharmacology; Place

1964
COMPARATIVE CHEMOTHERAPEUTIC TRIAL IN TREATMENT OF CHRONIC BORDERLINE PATIENTS.
    The American journal of psychiatry, 1964, Volume: 120

    Topics: Antidepressive Agents; Anxiety; Benactyzine; Depression; Depressive Disorder; Diazepam; Humans; Mepr

1964
ACTIVATING TRAINING IN THE TREATMENT OF DEPRESSIONS.
    Activitas nervosa superior, 1964, Volume: 6

    Topics: Benactyzine; Decision Making; Depression; Depressive Disorder; Exercise Therapy; Hobbies; Humans; Me

1964
[THERAPEUTIC EFFECTS OF A HYPNOTIC COMPOUND WITH TRANQUILIZING PROPERTIES].
    Lyon medical, 1964, Jun-07, Volume: 211

    Topics: Anxiety; Anxiety Disorders; Depression; Humans; Hypnotics and Sedatives; Meprobamate; Neurotic Disor

1964
[EXPERIENCE WITH STEMBAMATE].
    Nordisk psykiatrisk tidsskrift. Nordic journal of psychiatry, 1964, Volume: 18

    Topics: Anxiety; Anxiety Disorders; Depression; Depressive Disorder; Humans; Meprobamate; Neurotic Disorders

1964
[USE OF OXYLIDINE IN THE AMBULATORY TREATMENT OF MENTAL PATIENTS].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1963, Volume: 63

    Topics: Anxiety; Anxiety Disorders; Cardiovascular Diseases; Delusions; Depression; Guilt; Humans; Hypnotics

1963
REPORT OF AN UNUSUALLY LARGE DOSAGE OF METHYLPHENIDATE HYDROCHLORIDE.
    The American journal of psychiatry, 1964, Volume: 121

    Topics: Alcoholic Beverages; Benactyzine; Depression; Depressive Disorder; Imipramine; Meprobamate; Methylph

1964
THE DEPRESSION COMPLEX: A REVIEW OF THE HISTORY AND TREATMENT OF TWELVE PATIENTS.
    Journal of neuropsychiatry, 1964, Volume: 5

    Topics: Anxiety; Anxiety Disorders; Benactyzine; Bipolar Disorder; Depression; Drug Therapy; Humans; Mental

1964
SUSTAINED-ACTION AMPHETAMINE-MEPROBAMATE COMBINATION FOR THE TREATMENT OF OBESITY.
    Current therapeutic research, clinical and experimental, 1964, Volume: 6

    Topics: Amphetamine; Amphetamines; Appetite Depressants; Biomedical Research; Delayed-Action Preparations; D

1964
EARLY RECOGNITION OF DEPRESSION.
    Geriatrics, 1964, Volume: 19

    Topics: Amitriptyline; Amphetamine; Amphetamines; Barbiturates; Benactyzine; Chlordiazepoxide; Deanol; Depre

1964
Clinical trial of a new antidepressive agent.
    The Journal of the Medical Society of New Jersey, 1960, Volume: 57

    Topics: Antidepressive Agents; Depression; Depressive Disorder; Meprobamate; Parasympatholytics

1960
Treatment of depression in the elderly with a meprobamate-benactyzine hydrochloride combination (deprol).
    Antibiotic medicine & clinical therapy (New York, NY), 1960, Volume: 7

    Topics: Aged; Aged, 80 and over; Benactyzine; Depression; Depressive Disorder; Meprobamate; Parasympatholyti

1960
Deprol advertising.
    The Medical letter on drugs and therapeutics, 1967, Feb-24, Volume: 9, Issue:4

    Topics: Advertising; Benactyzine; Depression; Ethics, Pharmacy; Evaluation Studies as Topic; Humans; Meproba

1967
[Experimental study of the "'rebound syndrome" following discontinuation of prolonged phenazepam administration and possibilities for preventing it].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1981, Volume: 81, Issue:7

    Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Chlorpromazine; Conditioning, Clas

1981
Anxiolytic drugs.
    The Practitioner, 1975, Volume: 215, Issue:1288

    Topics: Adrenergic beta-Antagonists; Anthracenes; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Ant

1975
Tardive dyskinesia. A significant syndrome for geriatric dentistry.
    Oral surgery, oral medicine, and oral pathology, 1975, Volume: 39, Issue:1

    Topics: Aged; Arteriosclerosis; Bruxism; Chlorpromazine; Dementia; Denture, Complete; Depression; Depressive

1975
Sleep and depression. IV. Longitudinal studies.
    The Journal of nervous and mental disease, 1971, Volume: 153, Issue:4

    Topics: Adult; Depression; Desipramine; Electroconvulsive Therapy; Ethynodiol Diacetate; Female; Hospitaliza

1971
[Procedure for assessing anxiety; therapeutic results].
    La Revue du praticien, 1972, Apr-21, Volume: 22, Issue:12

    Topics: Adjustment Disorders; Alcoholism; Antidepressive Agents; Anxiety; Bipolar Disorder; Depression; Diag

1972
[Amitriptyline, Differential activity of tricyclic antidepressive agents].
    La Nouvelle presse medicale, 1972, Nov-04, Volume: 1, Issue:39

    Topics: Adolescent; Aged; Amitriptyline; Antidepressive Agents; Chlordiazepoxide; Chlorprothixene; Depressio

1972
Dimensions of outpatient neurotic pathology: comparison of a clinical vrsus an empirical assessment.
    Journal of consulting and clinical psychology, 1970, Volume: 34, Issue:2

    Topics: Anxiety; Chlordiazepoxide; Depression; Factor Analysis, Statistical; Female; Hostility; Humans; Male

1970
[Trial of G. 35020 in 52 cases of depression].
    Annales medico-psychologiques, 1968, Volume: 1, Issue:1

    Topics: Adult; Aged; Bipolar Disorder; Depression; Depressive Disorder, Major; Desipramine; Female; Humans;

1968
The addictive process in unusual addictions: a further elaboration of etiology.
    The American journal of psychiatry, 1969, Volume: 125, Issue:9

    Topics: Body Image; Defense Mechanisms; Depression; Ego; Fantasy; Female; Frustration; Habits; Humans; Male;

1969
Factors of symptom distress. Doctor ratings of anxious neurotic outpatients.
    Archives of general psychiatry, 1969, Volume: 21, Issue:3

    Topics: Anxiety Disorders; Cognition Disorders; Depression; Factor Analysis, Statistical; Fear; Humans; Mepr

1969