n-methylaspartate has been researched along with Depression in 43 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (4.65) | 29.6817 |
| 2010's | 25 (58.14) | 24.3611 |
| 2020's | 16 (37.21) | 2.80 |
| Authors | Studies |
|---|---|
| Min, R; Neubauer, FB; Nevian, T | 1 |
| Bhatia, NY; Doshi, GM; Kale, PP; Ved, HS | 1 |
| Cai, D; Lou, W; Mao, X | 1 |
| Alami, A; Alexander, GC; Mattison, DR; Moore, TJ | 1 |
| Chae, WR; Deuter, CE; Kaczmarczyk, M; Nowacki, J; Otte, C; Piber, D; Wingenfeld, K | 1 |
| Cook, J; Halaris, A | 1 |
| Chen, ZZ; Gu, XH; Liu, X; Wang, W; Wu, HJ; Xu, LJ; Yang, G; Yang, YJ; Zheng, LL | 1 |
| Chen, F; Gao, M; Li, L; Li, Q; Peng, M; Wang, Y; Wu, Y; Yan, Y; Yang, J; Yang, L; Yang, X | 1 |
| Bonanno, G; Bonifacino, T; Di Cesare Mannelli, L; Farina, C; Ghelardini, C; Micheli, L; Milanese, M; Scherz, MW; Torazza, C | 1 |
| Brown, KA; Georgiou, P; Gould, TD; Thompson, SM; Yuan, P; Zanos, P; Zarate, CA | 1 |
| Coimbra, NC; de Freitas, RL; De Gregorio, D; Dos Santos, WF; Gobbi, G; Medeiros, AC; Medeiros, P; Ruggiero, RN; Silva Júnior, PI | 1 |
| Chen, G; Ge, R; Guo, X; Nie, C; Qian, S; Shen, Q; Sheng, L; Sun, Y; Wang, W; Xue, W; Yao, Y; Zhang, H; Zhang, Y; Zhou, T | 1 |
| Hashimoto, K | 1 |
| Amini-Khoei, H; Anjomshoa, M; Bagheri, E; Boroujeni, SN; Lorigooini, Z | 1 |
| Chuchmacz, J; Czarnecka, K; Szymański, P; Wójtowicz, P | 1 |
| Aman, W; Dehpour, AR; Haider, A; Khan, MI; Khan, SN; Mumtaz, F; Naveed, A; Nikoui, V; Ullah, N; Wahab, A; Zaman, H | 1 |
| Cai, E; Gao, Y; Li, H; Lin, M; Liu, S; Tang, G; Wang, R; Yang, H; Zhang, L; Zhao, Y; Zhu, H | 1 |
| Chen, Z; Li, Z; Zhang, H; Zhong, Z; Zhou, Z | 1 |
| Deyama, S; Duman, RS; Fogaça, MV; Fukumoto, K; Kato, T; Li, XY | 1 |
| Dou, M; Gong, A; Han, L; Liang, H; Ma, A; Wang, Q; Wu, Y | 1 |
| Farber, NB | 1 |
| Fariborzi, M; Higley, MJ; Lur, G | 1 |
| Adeyemi, OI; Akanmu, MA; Owolabi, RA | 1 |
| Bum, EN; Moto, FC; Ngoupaye, GT; Taiwe, GS; Talla, E | 1 |
| Dehpour, AR; Ejtemaei Mehr, S; Haj-Mirzaian, A; Kordjazy, N; Ostadhadi, S | 1 |
| Abraham, R; Nirogi, R; Shinde, A | 1 |
| Lu, XY; Wang, X; Zhang, D | 1 |
| Chen, L; Hong, J; Li, L; Lu, ZH; Qu, WJ; Sha, S; Yu, WF | 1 |
| Cortés, P; Harraz, MM; Snyder, SH; Tyagi, R | 1 |
| Björkholm, C; Feltmann, K; Jardemark, K; Konradsson-Geuken, Å; Malmerfelt, A; Marcus, MM; Möller, A; Påhlsson, N; Schilström, B; Svensson, TH | 1 |
| Dubrovina, NI; Zinovyev, DR; Zinovyeva, DV | 1 |
| Feng, ZZ; He, M; Qin, X; Yang, GY; Yang, ZC | 1 |
| Eby, GA; Eby, KL | 1 |
| Cichy, A; Dybała, M; Gołembiowska, K; Listos, J; Nowak, G; Pilc, A; Poleszak, E; Siwek, A; Sowa-Kućma, M; Szewczyk, B; Słotwiński, S; Wlaź, P; Wróbel, A | 1 |
| Ameli, R; Brutsche, NE; DiazGranados, N; Henter, ID; Ibrahim, LA; Luckenbaugh, DA; Machado-Vieira, R; Zarate, CA | 1 |
| Balen, Gde O; Budni, J; Fernandes, SC; Freitas, AE; Moretti, M; Rodrigues, AL | 1 |
| Dubrovina, NI; Zinov'eva, DV | 1 |
| Pałucha-Poniewiera, A; Pilc, A | 1 |
| Bavaresco, DV; Boeck, CR; Comim, CM; Damiani-Neves, M; Moojen, VK; Pescador, BB; Quevedo, J | 1 |
| Bettio, LE; Budni, J; Colla, AR; Cunha, MP; Oliveira, Á; Pazini, FL; Rodrigues, AL | 1 |
| Kaster, MP; Machado, DG; Rodrigues, AL; Santos, AR | 1 |
| Pathak, S; Smith, MA | 1 |
| Hughes, IP; Lawford, BR; Morris, CP; Swagell, CD; Voisey, J; Young, RM | 1 |
4 review(s) available for n-methylaspartate and Depression
| Article | Year |
|---|---|
Importance of Exploring N-Methyl-D-Aspartate (NMDA) as a Future Perspective Target in Depression.
Topics: Animals; Antidepressive Agents; Depression; Depressive Disorder, Major; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate | 2022 |
Safety and effectiveness of NMDA receptor antagonists for depression: A multidisciplinary review.
Topics: Animals; Depression; Humans; Ketamine; Mammals; N-Methylaspartate; Phencyclidine; Receptors, N-Methyl-D-Aspartate | 2022 |
Memantine in neurological disorders - schizophrenia and depression.
Topics: Alzheimer Disease; Antidepressive Agents; Antipsychotic Agents; Clinical Trials as Topic; Depression; Drug Repositioning; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Memantine; N-Methylaspartate; Neuronal Plasticity; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Serotonin 5-HT3 Receptor Antagonists | 2021 |
Magnesium for treatment-resistant depression: a review and hypothesis.
Topics: Animals; Antidepressive Agents, Tricyclic; Brain; Clinical Trials as Topic; D-Aspartic Acid; Depression; Depressive Disorder; Depressive Disorder, Major; Fast Foods; Humans; Imipramine; Magnesium; Magnesium Deficiency; Mental Disorders; Models, Neurological; N-Methylaspartate; Randomized Controlled Trials as Topic; Suicide, Attempted | 2010 |
2 trial(s) available for n-methylaspartate and Depression
| Article | Year |
|---|---|
No influence of mineralocorticoid and glutamatergic NMDA receptor stimulation on spatial learning and memory in individuals with major depression.
Topics: Adult; Depression; Depressive Disorder, Major; Female; Hippocampus; Humans; Male; Maze Learning; Memory; Middle Aged; Mineralocorticoids; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Spatial Learning; Spatial Memory; Young Adult | 2022 |
Rapid resolution of suicidal ideation after a single infusion of an N-methyl-D-aspartate antagonist in patients with treatment-resistant major depressive disorder.
Topics: Adult; Antidepressive Agents; Depression; Depressive Disorder, Major; Diagnostic and Statistical Manual of Mental Disorders; Excitatory Amino Acid Antagonists; Female; Humans; Infusions, Intravenous; Ketamine; Male; Middle Aged; N-Methylaspartate; Psychiatric Status Rating Scales; Suicidal Ideation; Time Factors; Treatment Outcome | 2010 |
37 other study(ies) available for n-methylaspartate and Depression
| Article | Year |
|---|---|
Presynaptic NMDA Receptors Influence Ca
Topics: Animals; Calcium; Calcium Channels; Depression; Long-Term Synaptic Depression; N-Methylaspartate; Patch-Clamp Techniques; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Presynaptic; Synapses | 2022 |
Music alleviates pain perception in depression mouse models by promoting the release of glutamate in the hippocampus of mice to act on GRIK5.
Topics: Animals; Depression; Glutamic Acid; Hippocampus; Mice; Music; N-Methylaspartate; Pain; Pain Perception; Serotonin | 2022 |
Adjunctive dopaminergic enhancement of esketamine in treatment-resistant depression.
Topics: Bupropion; Depression; Depressive Disorder, Treatment-Resistant; Dopamine; Humans; Ketamine; N-Methylaspartate | 2022 |
Autophagy promotes membrane trafficking of NR2B to alleviate depression by inhibiting AQP4 expression in mice.
Topics: Animals; Autophagy; Depression; Hippocampus; Humans; Mice; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate | 2022 |
Anti-depressant-like effect of fermented Gastrodia elata Bl. by regulating monoamine levels and BDNF/NMDAR pathways in mice.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Brain-Derived Neurotrophic Factor; Depression; Disease Models, Animal; Dopamine; Gastrodia; Mice; Monoamine Oxidase; N-Methylaspartate; Plant Extracts; Propane; Receptors, N-Methyl-D-Aspartate; Serotonin; Stress, Psychological | 2023 |
Pharmacological Profile of MP-101, a Novel Non-racemic Mixture of R- and S-dimiracetam with Increased Potency in Rat Models of Cognition, Depression and Neuropathic Pain.
Topics: Animals; Cognition; D-Aspartic Acid; Depression; Glutamic Acid; N-Methylaspartate; Neuralgia; Rats | 2022 |
NMDA Receptor Activation-Dependent Antidepressant-Relevant Behavioral and Synaptic Actions of Ketamine.
Topics: Animals; Antidepressive Agents; Depression; Ketamine; Male; Mice; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate | 2023 |
Acanthoscurria gomesiana spider-derived Mygalin in the prelimbic prefrontal cortex modulates neuropathic pain and depression comorbid.
Topics: Animals; Antidepressive Agents; Comorbidity; Depression; Hyperalgesia; Male; N-Methylaspartate; Neuralgia; Prefrontal Cortex; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Spiders | 2023 |
Yueju-Ganmaidazao Decoction confers rapid antidepressant-like effects and the involvement of suppression of NMDA/NO/cGMP signaling.
Topics: Animals; Antidepressive Agents; Cyclic GMP; Depression; Drugs, Chinese Herbal; Mice; N-Methylaspartate; Nitric Oxide; Signal Transduction | 2020 |
Are NMDA and opioid receptors involved in the antidepressant actions of ketamine?
Topics: Animals; Antidepressive Agents; Depression; Ketamine; N-Methylaspartate; Receptors, Opioid; Rodentia | 2020 |
Possible Involvement of N-methyl-D-aspartate Receptor (NMDA-R) in the Antidepressant- like Effect of Trigonelline in Male Mice.
Topics: Alkaloids; Animals; Antidepressive Agents; Depression; Male; Mice; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate | 2020 |
Antidepressant-like effect of ethanol in mice forced swimming test is mediated via inhibition of NMDA/nitric oxide/cGMP signaling pathway.
Topics: Animals; Antidepressive Agents; Arginine; Cyclic GMP; Depression; Ethanol; Mice; N-Methylaspartate; Nitric Oxide; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Swimming | 2021 |
Ergosteryl 2-naphthoate, An Ergosterol Derivative, Exhibits Antidepressant Effects Mediated by the Modification of GABAergic and Glutamatergic Systems.
Topics: Animals; Antidepressive Agents; Bicuculline; Central Nervous System; Depression; Dopamine; Dose-Response Relationship, Drug; Ergosterol; gamma-Aminobutyric Acid; Glutamates; Mice; Motor Activity; N-Methylaspartate; Prazosin; Swimming | 2017 |
Ginsenoside Rg3 exerts anti-depressive effect on an NMDA-treated cell model and a chronic mild stress animal model.
Topics: Animals; Antidepressive Agents; Brain-Derived Neurotrophic Factor; Cyclic AMP Response Element-Binding Protein; Depression; Disease Models, Animal; Female; Ginsenosides; Hippocampus; Humans; Mental Disorders; Mice; Mice, Inbred C57BL; N-Methylaspartate; Neurons; Phosphorylation; Signal Transduction; Stress, Psychological | 2017 |
BDNF release and signaling are required for the antidepressant actions of GLYX-13.
Topics: Animals; Antidepressive Agents; Brain-Derived Neurotrophic Factor; Depression; Ketamine; Male; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; N-Methylaspartate; Oligopeptides; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptor, trkB; Receptors, N-Methyl-D-Aspartate; Signal Transduction | 2018 |
Improvement of symptoms in a rat model of depression through combined zinc and folic acid administration via up-regulation of the Trk B and NMDA.
Topics: Animals; Brain; Depression; Disease Models, Animal; Drug Therapy, Combination; Folic Acid; Male; N-Methylaspartate; Random Allocation; Rats; Rats, Sprague-Dawley; Receptor Protein-Tyrosine Kinases; Up-Regulation; Zinc | 2018 |
NMDA Antagonists for Treatment-Resistant Depression.
Topics: Depression; Depressive Disorder, Major; Humans; Ketamine; N-Methylaspartate; Pilot Projects | 2019 |
Ketamine disrupts neuromodulatory control of glutamatergic synaptic transmission.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Brain; Depression; Female; Glutamine; Ketamine; Male; Mice; Mice, Inbred C57BL; N-Methylaspartate; Neurons; Neurotransmitter Agents; Prefrontal Cortex; Receptors, AMPA; Receptors, GABA; Signal Transduction; Swimming; Synapses; Synaptic Potentials; Synaptic Transmission; Video Recording | 2019 |
Effects of ketamine and N-methyl-D-aspartate on fluoxetine-induced antidepressant-related behavior using the forced swimming test.
Topics: Animals; Antidepressive Agents, Second-Generation; Behavior, Animal; Depression; Fluoxetine; Ketamine; Mice; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Swimming; Synaptic Transmission | 2014 |
Antidepressant properties of aqueous macerate from Gladiolus dalenii corms.
Topics: 2-Amino-5-phosphonovalerate; Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents; Depression; Fluoxetine; Hindlimb Suspension; Imipramine; Iridaceae; Male; Medicine, African Traditional; Mice; Motor Activity; N-Methylaspartate; Phytotherapy; Plant Extracts; Receptors, N-Methyl-D-Aspartate; Selective Serotonin Reuptake Inhibitors; Stress, Psychological; Swimming | 2014 |
Opioid/NMDA receptors blockade reverses the depressant-like behavior of foot shock stress in the mouse forced swimming test.
Topics: Analgesics, Opioid; Animals; Behavior, Animal; Depression; Dizocilpine Maleate; Electroshock; Foot; Male; Mice; Morphine; Motor Activity; N-Methylaspartate; Naltrexone; Narcotic Antagonists; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid; Stress, Psychological; Swimming | 2014 |
Role of glutamate and advantages of combining memantine with a 5HT6 ligand in a model of depression.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Depression; Disease Models, Animal; Glutamic Acid; Ligands; Male; Memantine; Motor Activity; N-Methylaspartate; Piperazines; Prefrontal Cortex; Rats; Rats, Wistar; Serotonin; Serotonin Antagonists; Sulfonamides; Swimming | 2014 |
Dentate gyrus-CA3 glutamate release/NMDA transmission mediates behavioral despair and antidepressant-like responses to leptin.
Topics: Animals; Antidepressive Agents; CA3 Region, Hippocampal; Dentate Gyrus; Depression; Disease Models, Animal; Enzyme Inhibitors; Excitatory Amino Acid Agents; Gene Expression Regulation; Glutamic Acid; Leptin; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Motor Activity; N-Methylaspartate; Receptors, Leptin; RNA, Untranslated; Synapses; Synaptic Transmission; Wakefulness | 2015 |
Sex-related neurogenesis decrease in hippocampal dentate gyrus with depressive-like behaviors in sigma-1 receptor knockout mice.
Topics: Animals; Dentate Gyrus; Depression; Diestrus; Estradiol; Female; Male; Membrane Potentials; Mice, Knockout; N-Methylaspartate; Neurogenesis; Neurons; Ovariectomy; Proestrus; Receptors, N-Methyl-D-Aspartate; Receptors, sigma; Sex Characteristics; Sigma-1 Receptor | 2015 |
Antidepressant action of ketamine via mTOR is mediated by inhibition of nitrergic Rheb degradation.
Topics: Animals; Antidepressive Agents; Cells, Cultured; Cerebral Cortex; Cysteine; Depression; Disease Models, Animal; Embryo, Mammalian; Exploratory Behavior; Female; Gene Expression Regulation; HEK293 Cells; Humans; Ketamine; Male; Mice, Inbred C57BL; Mice, Knockout; Monomeric GTP-Binding Proteins; N-Methylaspartate; Neurons; Neuropeptides; Nitric Oxide; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Pregnancy; Proteolysis; Ras Homolog Enriched in Brain Protein; S-Nitrosothiols; Signal Transduction; Swimming; Time Factors; TOR Serine-Threonine Kinases | 2016 |
Alpha7 nicotinic acetylcholine receptor agonists and PAMs as adjunctive treatment in schizophrenia. An experimental study.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Antidepressive Agents; Antipsychotic Agents; Benzamides; Bridged Bicyclo Compounds; Citalopram; Depression; Disease Models, Animal; Dopamine; Excitatory Amino Acid Agonists; Male; N-Methylaspartate; Nicotinic Agonists; Phenylurea Compounds; Prefrontal Cortex; Pyramidal Cells; Rats, Sprague-Dawley; Rats, Wistar; Risperidone; Schizophrenia; Schizophrenic Psychology; Selective Serotonin Reuptake Inhibitors | 2016 |
N-methyl-D-aspartate receptors and amnesia in mice with depression-like state.
Topics: Amnesia; Analysis of Variance; Animals; Avoidance Learning; Behavior, Animal; Cycloserine; Depression; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Kynurenic Acid; Male; Mice; Mice, Inbred C57BL; N-Methylaspartate; Receptors, Amino Acid | 2007 |
[Relationship between learning and memory ability and expression of hippocampal N-methyl-D-aspartic acid (NMDA) in burn rats with depression].
Topics: Animals; Burns; Depression; Hippocampus; Maze Learning; Memory; N-Methylaspartate; Rats; Rats, Wistar | 2009 |
The involvement of NMDA and AMPA receptors in the mechanism of antidepressant-like action of zinc in the forced swim test.
Topics: Animals; Antidepressive Agents; Depression; Male; Mice; Motor Activity; N-Methylaspartate; Rats; Rats, Wistar; Receptors, AMPA; Swimming; Zinc | 2010 |
Involvement of nitric oxide-cGMP pathway in the antidepressant-like effect of ascorbic acid in the tail suspension test.
Topics: Animals; Antidepressive Agents; Arginine; Ascorbic Acid; Cyclic GMP; Depression; Disease Models, Animal; Dizocilpine Maleate; Enzyme Inhibitors; Exploratory Behavior; Female; Hindlimb Suspension; Indazoles; Mice; N-Methylaspartate; Nitric Oxide; Oxadiazoles; Piperazines; Purines; Quinoxalines; Signal Transduction; Sildenafil Citrate; Sulfones | 2011 |
[Interaction of N-methyl-D-aspartate and Dopamine D1 receptors in modulation of passive avoidance extinction at mice with depressive-like state].
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Avoidance Learning; Cycloserine; Depression; Depressive Disorder; Dopamine; Dopamine Agonists; Extinction, Psychological; Injections, Intraperitoneal; Male; Memory; Mice; Mice, Inbred C57BL; Models, Animal; N-Methylaspartate; Receptor Cross-Talk; Receptors, Dopamine D1; Receptors, N-Methyl-D-Aspartate | 2011 |
Involvement of mGlu5 and NMDA receptors in the antidepressant-like effect of acamprosate in the tail suspension test.
Topics: Acamprosate; Animals; Antidepressive Agents; Benzamides; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Hindlimb Suspension; Immobility Response, Tonic; Male; Mice; Mice, Inbred C57BL; Motor Activity; N-Methylaspartate; Pyrazoles; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Taurine | 2012 |
NMDA preconditioning prevents object recognition memory impairment and increases brain viability in mice exposed to traumatic brain injury.
Topics: Animals; Anxiety; Avoidance Learning; Behavior, Animal; Brain Injuries; Cell Survival; Depression; Hippocampus; Male; Memory Disorders; Mice; Motor Activity; N-Methylaspartate; Permeability; Recognition, Psychology; Visual Perception | 2012 |
Guanosine produces an antidepressant-like effect through the modulation of NMDA receptors, nitric oxide-cGMP and PI3K/mTOR pathways.
Topics: Analysis of Variance; Animals; Antidepressive Agents; Arginine; Cyclic GMP; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Agents; Exploratory Behavior; Female; Freezing Reaction, Cataleptic; Guanosine; Hindlimb Suspension; Immunosuppressive Agents; Male; Mice; N-Methylaspartate; Nitric Oxide; Phosphatidylinositol 3-Kinases; Receptors, N-Methyl-D-Aspartate; Serine; Signal Transduction; Sirolimus; Swimming; TOR Serine-Threonine Kinases | 2012 |
Involvement of NMDA receptors in the antidepressant-like action of adenosine.
Topics: Adenosine; Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Chlorides; Depression; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Synergism; Imipramine; Immobilization; Ketamine; Male; Mice; N-Methylaspartate; Receptor, Adenosine A1; Receptors, N-Methyl-D-Aspartate; Serine; Swimming; Time Factors; Zinc Compounds | 2012 |
The promise of rapidly acting antidepressants: challenges and opportunities.
Topics: Antidepressive Agents; Depression; Drug Discovery; Humans; Ketamine; N-Methylaspartate | 2012 |
NOS1AP is associated with increased severity of PTSD and depression in untreated combat veterans.
Topics: Adaptor Proteins, Signal Transducing; Adult; Combat Disorders; Depression; Depressive Disorder; Female; Humans; Male; Middle Aged; N-Methylaspartate; Stress Disorders, Post-Traumatic; Veterans; Vietnam Conflict | 2013 |