Page last updated: 2024-11-08

triiodothyronine and Depression

triiodothyronine has been researched along with Depression in 112 studies

Triiodothyronine: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.
3,3',5-triiodo-L-thyronine : An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.

Depression: Depressive states usually of moderate intensity in contrast with MAJOR DEPRESSIVE DISORDER present in neurotic and psychotic disorders.

Research Excerpts

ExcerptRelevanceReference
" Depression could result from changes in tryptophan availability caused by activation of the kynurenine pathway as a result of inflammation."9.14Kynurenine metabolites and inflammation markers in depressed patients treated with fluoxetine or counselling. ( Bridel, MA; Christofides, J; Cowlard, R; Darlington, LG; Forrest, CM; Mackay, GM; Mitchell, S; Stone, TW, 2009)
"To compare the effect of combination therapy with thyroxine (T(4)) and T(3) versus T(4) monotherapy in patients with hypothyroidism on stable T(4) substitution."9.14Effect of combination therapy with thyroxine (T4) and 3,5,3'-triiodothyronine versus T4 monotherapy in patients with hypothyroidism, a double-blind, randomised cross-over study. ( Faber, J; Jarløv, A; Jensen, EW; Kvetny, J; Nygaard, B, 2009)
" Beyond measuring serum levels of thyrotropin, free thyroxine, free triiodothyronine, and prolactin, before the beginning of the study and six months later, all enrolled patients completed questionnaires evaluating male sexual function (International Index of Erectile Func-tion-15: IIEF-15) and assessing the presence and severity of depressive symptoms (Beck Depression Inventory-Second Edition - BDI-II)."7.88Sexual function and depressive symptoms in young men with hypothyroidism receiving levothyroxine/liothyronine combination therapy. ( Krysiak, R; Marek, B; Okopień, B, 2018)
" Changes in kinetic parameters (V(max), maximal velocity and K(M), apparent Michaelis constant) of L-T3 uptake into red blood cells (RBCs) and changes in membrane fluidity in a group of 24 patients with major depression were measured before treatment and after 1 month of treatment with citalopram."7.73Red blood cell triiodothyronine uptake as membrane parameter of depression. ( Fisar, Z; Hanus, Z; Kalisová-Stárková, L; Paclt, I; Vevera, J, 2006)
"We report on two substance misusers with depression resistant to tricyclic antidepressant treatment who responded to triiodothyronine augmentation."7.71Triiodothyronine augmentation for the treatment of depression in substance misusers unresponsive to tricyclic antidepressants. ( Ho, TP; Kan, CK, 2001)
"Serum levels of thyroxine (T4), 3,3',5-triiodothyronine (T3), 3,3',5-triiodothyronine (rT3), 3,5-diiodothyronine (3,5-T2), 3,3'-diiodothyronine (3,3'-T2) and 3',5'-diiodothyronine (3',5'-T2) were studied in 80 patients with endogenous depression before and after electroconvulsive treatment (ECT)."7.66Altered serum levels of thyroxine, triiodothyronines and diiodothyronines in endogenous depression. ( Faber, J; Kirkegaard, C, 1981)
"We investigated the effects of T3 treatment on the depression-like behavior in male transgenic 3xTg-AD mice."5.72Triiodothyronine Treatment reverses Depression-Like Behavior in a triple-transgenic animal model of Alzheimer's Disease. ( Britto, LRG; da Conceição, RR; da Silva, REC; de Souza, JS; de Souza, TJL; do Nascimento, BPP; Giannocco, G; Laureano-Melo, R; Maciel, RMB; Maglione, AV; Penatti, CAA; Ribeiro, MO; Sato, MA, 2022)
" Depression could result from changes in tryptophan availability caused by activation of the kynurenine pathway as a result of inflammation."5.14Kynurenine metabolites and inflammation markers in depressed patients treated with fluoxetine or counselling. ( Bridel, MA; Christofides, J; Cowlard, R; Darlington, LG; Forrest, CM; Mackay, GM; Mitchell, S; Stone, TW, 2009)
"To compare the effect of combination therapy with thyroxine (T(4)) and T(3) versus T(4) monotherapy in patients with hypothyroidism on stable T(4) substitution."5.14Effect of combination therapy with thyroxine (T4) and 3,5,3'-triiodothyronine versus T4 monotherapy in patients with hypothyroidism, a double-blind, randomised cross-over study. ( Faber, J; Jarløv, A; Jensen, EW; Kvetny, J; Nygaard, B, 2009)
"Hypothyroidism may give rise to frank depression that usually responds to thyroxine therapy."4.80The thyroid axis and depression. ( Jackson, IM, 1998)
" Alterations in this axis, particularly low triiodothyronine syndrome, are a common neuroendocrine adaptation to semi-starvation in patients with anorexia nervosa (AN), who also frequently suffer from co-existing depressive symptoms."4.12Associations between pituitary-thyroid hormones and depressive symptoms in individuals with anorexia nervosa before and after weight-recovery. ( Bahnsen, K; Bauer, M; Ehrlich, S; Mirtschink, P; Poitz, DM; Roessner, V; Seidel, M; Steinhäuser, JL; Tam, FI; Wronski, ML, 2022)
" Beyond measuring serum levels of thyrotropin, free thyroxine, free triiodothyronine, and prolactin, before the beginning of the study and six months later, all enrolled patients completed questionnaires evaluating male sexual function (International Index of Erectile Func-tion-15: IIEF-15) and assessing the presence and severity of depressive symptoms (Beck Depression Inventory-Second Edition - BDI-II)."3.88Sexual function and depressive symptoms in young men with hypothyroidism receiving levothyroxine/liothyronine combination therapy. ( Krysiak, R; Marek, B; Okopień, B, 2018)
"The thyroid hormone triiodothyronine (T3) can be used as an augmentation therapy for depression."3.88Use of liothyronine (L-T3) as an augmentation therapy for depression during pregnancy. ( Bhella, VS; Garg, D, 2018)
" The Zhongshan Station crew experienced significant increases in fatigue, anger, tension, confusion, and decrease in free thyroxine (FT4), norepinephrine (NE), and epinephrine (E) during the winter, increase in thyrotropin (TSH) and total triiodothyronine (TT3) when returning, whereas their counterparts at Great Wall Station only experienced increased TT3 after deployment."3.83Different adaptations of Chinese winter-over expeditioners during prolonged Antarctic and sub-Antarctic residence. ( Chen, N; Li, H; Wu, Q; Xu, C; Zhang, T, 2016)
" All patients received the measurements of Zung Self-Rating Depression Scale (SDS) and serum thyroid stimulating hormone (TSH), free thyroxine (FT4), free triiodothyronine (FT3) and TSH receptor antibodies (TRAb)."3.80[Relationship between depression and thyroid hormone levels in patients with Graves disease]. ( Huang, H; Yan, YR; Yan, Z; Zeng, J, 2014)
"The aim of this study was to estimate the prevalence of depressive symptoms in patients affected by subclinical hypothyroidism by means of Hamilton Rating Scale for Depression (HAM-D) and Montgomery-Asberg Depression Rating Scale (MADRS); to assess which depressive symptoms are prevalent in our population, with references to the factorialization of HAM-D by Cleary and Guy (1977); to verify whether levothyroxine replacement therapy alone can induce total remission of depressive symptoms."3.76Prevalence of depression in patients affected by subclinical hypothyroidism. ( Demartini, B; Gambini, O; Masu, A; Pontiroli, AE; Scarone, S, 2010)
" The behavioral and neuroendocrinological effects of icariin, a major constituent of flavonoids isolated from Epimedium brevicornum, were investigated in the CMS model of depression in male Wistar rats."3.74Icariin from Epimedium brevicornum attenuates chronic mild stress-induced behavioral and neuroendocrinological alterations in male Wistar rats. ( Jiang, FX; Kong, LD; Kung, HF; Li, YC; Pan, Y; Xia, X, 2007)
" Changes in kinetic parameters (V(max), maximal velocity and K(M), apparent Michaelis constant) of L-T3 uptake into red blood cells (RBCs) and changes in membrane fluidity in a group of 24 patients with major depression were measured before treatment and after 1 month of treatment with citalopram."3.73Red blood cell triiodothyronine uptake as membrane parameter of depression. ( Fisar, Z; Hanus, Z; Kalisová-Stárková, L; Paclt, I; Vevera, J, 2006)
"We report on two substance misusers with depression resistant to tricyclic antidepressant treatment who responded to triiodothyronine augmentation."3.71Triiodothyronine augmentation for the treatment of depression in substance misusers unresponsive to tricyclic antidepressants. ( Ho, TP; Kan, CK, 2001)
"Many patients treated for primary hypothyroidism have an unexplained reduced quality of life (QOL)."2.80Quality of life in patients with primary hypothyroidism related to BMI. ( Berghout, A; Kelderman-Bolk, N; Tijssen, JP; Visser, TJ, 2015)
"Twenty patients with treatment-resistant depression received five 60-s 1-Hz trains over the right dorsolateral prefrontal cortex."2.75Changes in hypothalamic-pituitary-thyroid axis following successful treatment with low-frequency right prefrontal transcranial magnetic stimulation in treatment-resistant depression. ( Fujita, K; Hasegawa, T; Kito, S; Koga, Y, 2010)
"Women with PTSD-CSA showed significant elevations in Total T3 and the TT3/free thyroxine (TT3/FT4) ratio, the FT3/TT3 ratio, and modest reductions in thyroid stimulating hormone relative to our community sample."2.71Thyroid hormone alterations among women with posttraumatic stress disorder due to childhood sexual abuse. ( Friedman, MJ; Jalowiec, JE; McDonagh-Coyle, A; McHugo, GJ; Wang, S, 2005)
"The Clinician-Administered PTSD Scale, the 21-item Hamilton Rating Scale for Depression, and the Clinical Global Impressions-Severity of Illness scale were administered every 2 weeks, and self-assessments were performed with a 100 mm visual analog mood scale."2.70Triiodothyronine augmentation of selective serotonin reuptake inhibitors in posttraumatic stress disorder. ( Agid, O; Lerer, B; Shalev, AY, 2001)
"Depression is a multicausal disorder and has been associated with the risk to develop cancer, dementia, diabetes, epilepsy and stroke."2.49Molecular mechanisms of depression: perspectives on new treatment strategies. ( Borgwardt, S; Lang, UE, 2013)
"Hypothyroidism impacts aspects of cognitive functioning and mood."2.44Neuropsychiatric aspects of hypothyroidism and treatment reversibility. . ( Davis, JD; Tremont, G, 2007)
"Subclinical hyperthyroidism is associated with atrial fibrillation, osteoporosis and dementia."2.42[Subclinical functional disorders of the thyroid gland]. ( Corssmit, EP; Wiersinga, WM, 2003)
" In patients who have experienced only partial treatment results, the clinician should first consider optimizing antidepressant dosage or lengthening therapy."2.40Practical management of treatment-resistant depression. ( Cadieux, RJ, 1998)
" Using drugs together may increase the risk of adverse effects, through potentiation of existing adverse effects or alterations in plasma concentrations of the drug."2.40Risk of adverse events with the use of augmentation therapy for the treatment of resistant depression. ( Schweitzer, I; Tuckwell, V, 1998)
"The use of thyroid hormones in the treatment of depression is reviewed."2.39Thyroid hormone treatment of depression. ( Joffe, RT; Singer, W; Sokolov, ST, 1995)
"We investigated the effects of T3 treatment on the depression-like behavior in male transgenic 3xTg-AD mice."1.72Triiodothyronine Treatment reverses Depression-Like Behavior in a triple-transgenic animal model of Alzheimer's Disease. ( Britto, LRG; da Conceição, RR; da Silva, REC; de Souza, JS; de Souza, TJL; do Nascimento, BPP; Giannocco, G; Laureano-Melo, R; Maciel, RMB; Maglione, AV; Penatti, CAA; Ribeiro, MO; Sato, MA, 2022)
"Starvation affects thyroid hormone status and thyroid hypofunction is in turn associated with depressed mood."1.36Do thyroid hormones mediate the effects of starvation on mood in adolescent girls with eating disorders? ( Rosling, A; Swenne, I, 2010)
"High levels of tension-anxiety and confusion were preceded by declines in free T3 and T4."1.31Circannual pattern of hypothalamic-pituitary-thyroid (HPT) function and mood during extended antarctic residence. ( Case, HS; Do, NV; Finney, NS; Palinkas, LA; Reed, HL; Reedy, KR, 2001)
"Refractory depressions are depressions that respond insufficiently to treatment with the standard antidepressants, given long enough and in adequate dosage."1.30[Treatment of refractory primary depression]. ( van Praag, HM, 1997)
" The importance of adequate dosage and duration in any treatment trial are emphasized, and the evidence in support of combined antidepressants, lithium-antidepressant combinations, the addition of triiodothyronine or tryptophan, the use of anticonvulsants, and the use of vanadium inactivators, is evaluated."1.27Pharmacological strategies in depression. ( Barnes, TR; Katona, CL, 1985)
"In 11 patients with chronic renal failure serum 3'-T1 levels were highly increased 285 pmol/l (115 - 1538 pmol/l) (P less than 0."1.26Serum 3'-monoiodothyronine levels in normal subjects and in patients with thyroid and non-thyroid disease. ( Cohn, D; Faber, J; Friis, T; Kirkegaard, C; Kølendorf, K; Lumholtz, IB; Siersbaek-Nielsen, K; Thomsen, HF, 1981)
"The TSH response in the groups with reactive depression, reactive paranoid psychosis, and neurotic depression, respectively, did not differ significantly from that found in controls."1.26Thyrotrophin-releasing hormone (TRH) stimulation test in manic-depressive illness. ( Bjørum, N; Cohn, D; Kirkegaard, C; Lauridsen, UB, 1978)

Research

Studies (112)

TimeframeStudies, this research(%)All Research%
pre-199045 (40.18)18.7374
1990's16 (14.29)18.2507
2000's24 (21.43)29.6817
2010's24 (21.43)24.3611
2020's3 (2.68)2.80

Authors

AuthorsStudies
Wronski, ML1
Tam, FI1
Seidel, M1
Mirtschink, P1
Poitz, DM1
Bahnsen, K1
Steinhäuser, JL1
Bauer, M2
Roessner, V1
Ehrlich, S1
Maglione, AV1
do Nascimento, BPP1
Ribeiro, MO2
de Souza, TJL1
da Silva, REC1
Sato, MA1
Penatti, CAA1
Britto, LRG1
de Souza, JS1
Maciel, RMB1
da Conceição, RR1
Laureano-Melo, R1
Giannocco, G1
Flach, E1
Koenig, J1
van der Venne, P1
Parzer, P1
Resch, F1
Kaess, M1
Qu, P1
Yu, JX1
Xia, L1
Chen, GH1
Peng, R1
Li, Y1
Krysiak, R2
Marek, B1
Okopień, B2
Szkróbka, W1
Ostan, R1
Monti, D1
Mari, D1
Arosio, B1
Gentilini, D1
Ferri, E1
Passarino, G1
De Rango, F1
D'Aquila, P1
Mariotti, S1
Pasquali, R1
Fanelli, F1
Bucci, L1
Franceschi, C1
Vitale, G1
Bhella, VS1
Garg, D1
Taroza, S1
Rastenytė, D1
Burkauskas, J1
Podlipskytė, A1
Mickuvienė, N1
Bunevicius, A1
Deltuva, V1
Tamasauskas, S1
Tamasauskas, A1
Laws, ER1
Bunevicius, R1
Lang, UE2
Borgwardt, S1
Ge, JF1
Peng, YY1
Qi, CC1
Chen, FH1
Zhou, JN1
Zeng, J1
Yan, YR1
Yan, Z1
Huang, H1
Fjaellegaard, K1
Kvetny, J2
Allerup, PN1
Bech, P1
Ellervik, C1
Kelderman-Bolk, N1
Visser, TJ1
Tijssen, JP1
Berghout, A1
Chen, N1
Wu, Q1
Li, H1
Zhang, T1
Xu, C1
Bocco, BM1
Werneck-de-Castro, JP1
Oliveira, KC1
Fernandes, GW1
Fonseca, TL1
Nascimento, BP1
McAninch, EA1
Ricci, E1
Kvárta-Papp, Z1
Fekete, C1
Bernardi, MM1
Gereben, B1
Bianco, AC1
Özgür, E1
Gürbüz Özgür, B1
Aksu, H1
Cesur, G1
Jeong, HS1
Choi, EK1
Song, IU1
Chung, YA1
Park, JS1
Oh, JK1
Mackay, GM1
Forrest, CM1
Christofides, J1
Bridel, MA1
Mitchell, S1
Cowlard, R1
Stone, TW1
Darlington, LG1
Palinkas, LA2
Reedy, KR2
Shepanek, M1
Reeves, D1
Samuel Case, H1
Van Do, N1
Lester Reed, H1
Nygaard, B1
Jensen, EW1
Jarløv, A1
Faber, J3
Eitan, R1
Landshut, G1
Lifschytz, T3
Einstein, O1
Ben-Hur, T1
Lerer, B4
Kito, S1
Hasegawa, T1
Fujita, K1
Koga, Y1
Swenne, I1
Rosling, A1
Pilhatsch, M1
Winter, C1
Nordström, K1
Vennström, B1
Juckel, G1
Demartini, B1
Masu, A1
Scarone, S1
Pontiroli, AE1
Gambini, O1
Grigorova, M1
Sherwin, BB1
Corssmit, EP1
Wiersinga, WM1
BAUER, HG1
McGAVACK, TH1
SWELL, L1
Sawka, AM1
Gerstein, HC1
Marriott, MJ1
MacQueen, GM1
Joffe, RT3
Lee, IT1
Sheu, WH1
Liau, YJ1
Lin, SY1
Lee, WJ1
Lin, CC1
Gussekloo, J2
van Exel, E2
de Craen, AJ2
Meinders, AE2
Frölich, M2
Westendorp, RG2
Friedman, MJ1
Wang, S1
Jalowiec, JE1
McHugo, GJ1
McDonagh-Coyle, A1
Kalisová-Stárková, L1
Fisar, Z1
Paclt, I1
Hanus, Z1
Vevera, J1
Shalom, G2
Newman, ME2
Jellinger, PS1
Segman, R1
Gur, E1
Golzer, T1
Fliers, E1
Unmehopa, UA1
Alkemade, A1
Davis, JD1
Tremont, G1
Pan, Y1
Kong, LD1
Li, YC1
Xia, X1
Kung, HF1
Jiang, FX1
Frey, A1
Lampert, A1
Dietz, K1
Striebich, S1
Locher, C1
Fedorenko, O1
Möhle, R1
Gallinat, J1
Lang, F1
Chaput, JP1
Arguin, H1
Gagnon, C1
Tremblay, A1
Loosen, PT1
Prange, AJ7
Gambert, SR1
Pontzer, CP1
Dagon, EM1
Kirkegaard, C5
Köbberling, J1
Hintze, G1
Blossey, HC1
Dirks, H1
Emrich, D1
Mayer, G1
Schicha, H1
Cohn, D2
Kølendorf, K1
Thomsen, HF1
Lumholtz, IB1
Siersbaek-Nielsen, K1
Friis, T1
Steiner, M1
Portnoi, VA1
Oppenheimer, JH1
Braverman, LE1
Toft, A1
Jackson, IM2
Ladenson, PW1
Sokolov, ST1
Singer, W1
van Praag, HM1
Baldini, IM1
Vita, A1
Mauri, MC1
Amodei, V1
Carrisi, M1
Bravin, S1
Cantalamessa, L1
Coiro, V1
Volpi, R1
Marchesi, C1
DeFerri, A1
Capretti, L1
Caffarri, G1
Colla, R1
Chiodera, P1
Vorel-Havelkova, E1
Brombacher, PJ1
Levitt, AJ1
Wesson, VA1
Goichot, B1
Schlienger, JL1
Cadieux, RJ1
Schweitzer, I1
Tuckwell, V1
Bellipanni, G1
Bianchi, P1
Pierpaoli, W1
Bulian, D1
Ilyia, E1
Reed, HL1
Do, NV1
Case, HS1
Finney, NS1
Nimmagadda, RR1
Agid, O1
Shalev, AY1
Redei, EE1
Solberg, LC2
Kluczynski, JM1
Pare, WP1
Olson, SL1
Turek, FW1
Redei, E1
Kan, CK1
Ho, TP1
Hatotani, N1
Nomura, J1
Yamaguchi, T1
Kitayama, I1
Bjørum, N1
Lauridsen, UB3
Linnoila, M1
Lamberg, BA1
Rosberg, G1
Karonen, SL1
Welin, MG1
Tsutsui, S1
Yamazaki, Y1
Namba, T1
Tsushima, M1
Orth, JP1
Braccini, T1
Krebs, BP1
Darcourt, G1
Paasche, I1
Garbutt, J1
Malekpour, B1
Brunswick, D1
Jonnalagadda, MR1
Jolliff, L1
Podolak, R1
Wilson, I1
Prange, A1
Schechter, MD1
Chance, WT1
Spaulding, SW1
Burrow, GN1
Ramey, JN1
Donabedian, RK1
Slusher, N1
Norlem, N2
Bjorum, N2
Nordgren, L1
von Schéele, C1
Mountjoy, CQ1
Daskalopoulos, NT1
Brillet, AM1
Caron, J1
Cottereau, MJ1
Deniker, P1
Banki, CM1
Bánki, C1
Shader, RI1
Harsch, I1
Paschke, R1
Usadel, KH1
Drago, F1
Pulvirenti, L1
Spadaro, F1
Pennisi, G1
Maes, M1
Vandewoude, M1
Schotte, C1
Martin, M1
D'Hondt, P1
Scharpe, S1
Blockx, P1
Sakaue, K1
Chopra, IJ1
Solomon, DH1
Huang, TS1
Rifkin, A1
Lavretskaia, EF1
Tenidieva, VD1
Lavretskaia, GI1
Katona, CL1
Barnes, TR1
Taylor, JT1
Fisher, R1
Wilson, IC5
Rabon, AM2
Lipton, MA4
Takahashi, S1
Kondo, H1
Yoshimura, M1
Ochi, Y1
Nelson, JH1
Ogura, C1
Okuma, T1
Uchida, Y1
Imai, S1
Yogi, H1
Wheatley, D2
Coppen, A2
Whybrow, PC2
Noguera, R2
Maggs, R1
Bailey, JE1
Feighner, JP1
King, LJ1
Schuckit, MA1
Croughan, J1
Briscoe, W1
Abdel-Gawad, MS1
Askar, AM1
el-Rakhawy, YT1
McClane, TK3
Knox, AE1
Breese, GR1
Martin, BR1
Alltop, LB1
Shafer, N1
Knox, A1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Desiccated Thyroid Extract Compared to Levothyroxine in the Treatment of Hypothyroidism: A Randomized, Double-blind, Crossover Study.[NCT01739972]180 participants (Anticipated)Interventional2012-05-31Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

13 reviews available for triiodothyronine and Depression

ArticleYear
Molecular mechanisms of depression: perspectives on new treatment strategies.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2013, Volume: 31, Issue:6

    Topics: Antidepressive Agents; Brain-Derived Neurotrophic Factor; Cyclooxygenase 2; Cytokines; Depression; E

2013
[Subclinical functional disorders of the thyroid gland].
    Nederlands tijdschrift voor geneeskunde, 2003, Jun-14, Volume: 147, Issue:24

    Topics: Depression; Fatigue; Humans; Hyperthyroidism; Hypothyroidism; Risk Factors; Thyroid Diseases; Thyroi

2003
Basic mechanisms of augmentation of antidepressant effects with thyroid hormone.
    Current drug targets, 2006, Volume: 7, Issue:2

    Topics: Animals; Antidepressive Agents; Depression; Drug Synergism; Drug Therapy, Combination; Humans; Micro

2006
Functional neuroanatomy of thyroid hormone feedback in the human hypothalamus and pituitary gland.
    Molecular and cellular endocrinology, 2006, Jun-07, Volume: 251, Issue:1-2

    Topics: Critical Illness; Depression; Feedback, Physiological; Humans; Hypothalamus; Iodide Peroxidase; Iodo

2006
Neuropsychiatric aspects of hypothyroidism and treatment reversibility. .
    Minerva endocrinologica, 2007, Volume: 32, Issue:1

    Topics: Adult; Age Factors; Aged; Animals; Autoantibodies; Brain; Cerebrovascular Circulation; Cognition Dis

2007
A therapeutic controversy. Thyroid hormone treatment: when and what?
    The Journal of clinical endocrinology and metabolism, 1995, Volume: 80, Issue:10

    Topics: Depression; Humans; Hypothyroidism; Therapeutic Equivalency; Thyrotropin-Releasing Hormone; Thyroxin

1995
Thyroid hormone treatment of depression.
    Thyroid : official journal of the American Thyroid Association, 1995, Volume: 5, Issue:3

    Topics: Antidepressive Agents; Depression; Drug Therapy, Combination; Humans; Thyroid Hormones; Treatment Ou

1995
[Non-thyroid indications of treatment with thyroid hormones].
    La Revue de medecine interne, 1998, Volume: 19, Issue:10

    Topics: Animals; Cardiac Surgical Procedures; Cardiomyopathies; Cardiovascular System; Clinical Trials as To

1998
The thyroid axis and depression.
    Thyroid : official journal of the American Thyroid Association, 1998, Volume: 8, Issue:10

    Topics: Adult; Depression; Female; Humans; Hypothyroidism; Male; Middle Aged; Thyroid Diseases; Thyroid Glan

1998
Practical management of treatment-resistant depression.
    American family physician, 1998, Volume: 58, Issue:9

    Topics: Antidepressive Agents; Buspirone; Depression; Drug Resistance; Drug Therapy, Combination; Humans; Li

1998
Risk of adverse events with the use of augmentation therapy for the treatment of resistant depression.
    Drug safety, 1998, Volume: 19, Issue:6

    Topics: Antidepressive Agents; Antidepressive Agents, Tricyclic; Depression; Drug Resistance; Drug Therapy,

1998
Thyroid hormone in the treatment of depression.
    Southern medical journal, 1975, Volume: 68, Issue:8

    Topics: Depression; Drug Therapy, Combination; Electroconvulsive Therapy; Humans; Imipramine; Injections, In

1975
The possible role of thyroid and thyrotrophic hormones in depressive illness.
    Postgraduate medical journal, 1976, Volume: 52, Issue:3 suppl

    Topics: Depression; Electroconvulsive Therapy; Humans; Imipramine; Mental Status Schedule; Thyrotropin; Thyr

1976

Trials

20 trials available for triiodothyronine and Depression

ArticleYear
Sexual function and depressive symptoms in young women with hypothyroidism receiving levothyroxine/liothyronine combination therapy: a pilot study.
    Current medical research and opinion, 2018, Volume: 34, Issue:9

    Topics: Adult; Depression; Female; Humans; Hypothyroidism; Medication Therapy Management; Middle Aged; Pilot

2018
Quality of life in patients with primary hypothyroidism related to BMI.
    European journal of endocrinology, 2015, Volume: 173, Issue:4

    Topics: Adult; Anxiety; Autoantibodies; Autoantigens; Body Mass Index; Depression; Female; Hormone Replaceme

2015
Kynurenine metabolites and inflammation markers in depressed patients treated with fluoxetine or counselling.
    Clinical and experimental pharmacology & physiology, 2009, Volume: 36, Issue:4

    Topics: Adult; Antidepressive Agents; Biomarkers; Counseling; Depression; Drug Therapy, Combination; Female;

2009
A randomized placebo-controlled clinical trial of the effectiveness of thyroxine and triiodothyronine and short-term exposure to bright light in prevention of decrements in cognitive performance and mood during prolonged Antarctic residence.
    Clinical endocrinology, 2010, Volume: 72, Issue:4

    Topics: Adult; Affect; Anger; Antarctic Regions; Cognition; Depression; Female; Humans; Lighting; Male; Phot

2010
Effect of combination therapy with thyroxine (T4) and 3,5,3'-triiodothyronine versus T4 monotherapy in patients with hypothyroidism, a double-blind, randomised cross-over study.
    European journal of endocrinology, 2009, Volume: 161, Issue:6

    Topics: Adolescent; Adult; Aged; Antithyroid Agents; Cross-Over Studies; Depression; Drug Therapy, Combinati

2009
Changes in hypothalamic-pituitary-thyroid axis following successful treatment with low-frequency right prefrontal transcranial magnetic stimulation in treatment-resistant depression.
    Psychiatry research, 2010, Jan-30, Volume: 175, Issue:1-2

    Topics: Adult; Aged; Analysis of Variance; Depression; Female; Functional Laterality; Humans; Hypothalamo-Hy

2010
Does a combination regimen of thyroxine (T4) and 3,5,3'-triiodothyronine improve depressive symptoms better than T4 alone in patients with hypothyroidism? Results of a double-blind, randomized, controlled trial.
    The Journal of clinical endocrinology and metabolism, 2003, Volume: 88, Issue:10

    Topics: Adult; Affect; Depression; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypothyro

2003
Thyroid hormone alterations among women with posttraumatic stress disorder due to childhood sexual abuse.
    Biological psychiatry, 2005, May-15, Volume: 57, Issue:10

    Topics: Adult; Child; Child Abuse, Sexual; Depression; Female; Humans; Neuropsychological Tests; Psychiatric

2005
Impact of suppression of thyroxine on folate status during acute antidepressant therapy.
    Psychiatry research, 1998, Jun-15, Volume: 79, Issue:2

    Topics: Adult; Analysis of Variance; Antidepressive Agents, Tricyclic; Chi-Square Distribution; Depression;

1998
Effects of melatonin in perimenopausal and menopausal women: a randomized and placebo controlled study.
    Experimental gerontology, 2001, Volume: 36, Issue:2

    Topics: Adult; Affect; Circadian Rhythm; Depression; Double-Blind Method; Female; Follicle Stimulating Hormo

2001
Triiodothyronine augmentation of selective serotonin reuptake inhibitors in posttraumatic stress disorder.
    The Journal of clinical psychiatry, 2001, Volume: 62, Issue:3

    Topics: Adult; Ambulatory Care; Depression; Drug Administration Schedule; Drug Therapy, Combination; Female;

2001
Thyroid hormones and TSH, prolactin and LH responses to repeated TRH and LRH injections in depressed patients.
    Acta psychiatrica Scandinavica, 1979, Volume: 59, Issue:5

    Topics: Adult; Clinical Trials as Topic; Depression; Double-Blind Method; Female; Gonadotropin-Releasing Hor

1979
[The psychotropic action of TRH].
    L'Encephale, 1979, Volume: 5, Issue:4

    Topics: Adult; Anxiety; Clinical Trials as Topic; Depression; Double-Blind Method; Female; Humans; Male; Men

1979
Enhancement of imipramine antidepressant activity by thyroid hormone.
    The American journal of psychiatry, 1969, Volume: 126, Issue:4

    Topics: Achilles Tendon; Adult; Clinical Trials as Topic; Depression; Drug Synergism; Female; Humans; Imipra

1969
Potentiation of amitriptyline by thyroid hormone.
    Archives of general psychiatry, 1972, Volume: 26, Issue:3

    Topics: Adult; Age Factors; Amitriptyline; Clinical Trials as Topic; Depression; Drug Synergism; Evaluation

1972
The comparative antidepressant value of L-tryptophan and imipramine with and without attempted potentiation by liothyronine.
    Archives of general psychiatry, 1972, Volume: 26, Issue:3

    Topics: Clinical Trials as Topic; Depression; Drug Combinations; Drug Synergism; Evaluation Studies as Topic

1972
Thyroid function and the response to liothyronine in depression.
    Archives of general psychiatry, 1972, Volume: 26, Issue:3

    Topics: Ankle; Cholesterol; Clinical Trials as Topic; Depression; Evaluation Studies as Topic; Female; Human

1972
Hormonal potentiation of imipramine and ECT in primary depression.
    The American journal of psychiatry, 1972, Volume: 128, Issue:10

    Topics: Adolescent; Adult; Affective Symptoms; Aged; Clinical Trials as Topic; Depression; Dexamethasone; Dr

1972
Evaluation of psychotropic drugs in general practice.
    Proceedings of the Royal Society of Medicine, 1972, Volume: 65, Issue:4

    Topics: Amitriptyline; Antidepressive Agents; Anxiety; Chlordiazepoxide; Clinical Trials as Topic; Depressio

1972
Thyroid-hormone enhancement of imipramine in nonretarded depressions.
    The New England journal of medicine, 1970, May-07, Volume: 282, Issue:19

    Topics: Blood Proteins; Clinical Trials as Topic; Depression; Drug Synergism; Female; Hospitalization; Human

1970

Other Studies

79 other studies available for triiodothyronine and Depression

ArticleYear
Associations between pituitary-thyroid hormones and depressive symptoms in individuals with anorexia nervosa before and after weight-recovery.
    Psychoneuroendocrinology, 2022, Volume: 137

    Topics: Anorexia Nervosa; Cross-Sectional Studies; Depression; Female; Humans; Longitudinal Studies; Thinnes

2022
Triiodothyronine Treatment reverses Depression-Like Behavior in a triple-transgenic animal model of Alzheimer's Disease.
    Metabolic brain disease, 2022, Volume: 37, Issue:8

    Topics: Alzheimer Disease; Animals; Depression; Disease Models, Animal; Glycogen Synthase Kinase 3; Male; Mi

2022
Hypothalamic-pituitary-thyroid axis function in female adolescent nonsuicidal self-injury and its association with comorbid borderline personality disorder and depression.
    Progress in neuro-psychopharmacology & biological psychiatry, 2021, 12-20, Volume: 111

    Topics: Adolescent; Borderline Personality Disorder; Comorbidity; Depression; Female; Humans; Hypothalamo-Hy

2021
Cognitive Performance and the Alteration of Neuroendocrine Hormones in Chronic Tension-Type Headache.
    Pain practice : the official journal of World Institute of Pain, 2018, Volume: 18, Issue:1

    Topics: Adrenocorticotropic Hormone; Adult; Case-Control Studies; Chronic Disease; Cognition; Cognitive Dysf

2018
Low serum thyroid-stimulating hormone levels are associated with lipid profile in depressive patients with long symptom duration.
    Journal of affective disorders, 2017, 08-01, Volume: 217

    Topics: Adult; Aged; Cholesterol, HDL; Cholesterol, LDL; Cross-Sectional Studies; Depression; Female; Humans

2017
Sexual function and depressive symptoms in young men with hypothyroidism receiving levothyroxine/liothyronine combination therapy.
    Endokrynologia Polska, 2018, Volume: 69, Issue:1

    Topics: Adult; Depression; Drug Therapy, Combination; Hormone Replacement Therapy; Humans; Hypothyroidism; M

2018
Heterogeneity of Thyroid Function and Impact of Peripheral Thyroxine Deiodination in Centenarians and Semi-Supercentenarians: Association With Functional Status and Mortality.
    The journals of gerontology. Series A, Biological sciences and medical sciences, 2019, 05-16, Volume: 74, Issue:6

    Topics: Aged; Aged, 80 and over; Aging; Blood Proteins; Cholesterol, HDL; Cognition; Depression; Disability

2019
Use of liothyronine (L-T3) as an augmentation therapy for depression during pregnancy.
    BMJ case reports, 2018, Dec-07, Volume: 11, Issue:1

    Topics: Adult; Chemotherapy, Adjuvant; Depression; Female; Humans; Pregnancy; Pregnancy Complications; Selec

2018
Lower serum free triiodothyronine levels are associated with symptoms of depression after ischemic stroke.
    Journal of psychosomatic research, 2019, Volume: 122

    Topics: Aged; Depression; Female; Humans; Male; Middle Aged; Risk Factors; Stroke; Triiodothyronine

2019
Low triiodothyronine syndrome as a predictor of poor outcomes in patients undergoing brain tumor surgery: a pilot study: clinical article.
    Journal of neurosurgery, 2013, Volume: 118, Issue:6

    Topics: Aged; Anxiety; Biomarkers; Brain Neoplasms; Depression; Female; Follow-Up Studies; Humans; Male; Mid

2013
Depression-like behavior in subclinical hypothyroidism rat induced by hemi-thyroid electrocauterization.
    Endocrine, 2014, Volume: 45, Issue:3

    Topics: Adrenal Cortex; Animals; Behavior, Animal; Corticosterone; Depression; Disease Models, Animal; Elect

2014
[Relationship between depression and thyroid hormone levels in patients with Graves disease].
    Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2014, Volume: 45, Issue:3

    Topics: Depression; Graves Disease; Humans; Immunoglobulins, Thyroid-Stimulating; Radiopharmaceuticals; Risk

2014
Well-being and depression in individuals with subclinical hypothyroidism and thyroid autoimmunity - a general population study.
    Nordic journal of psychiatry, 2015, Volume: 69, Issue:1

    Topics: Adult; Autoantibodies; Autoimmunity; Biomarkers; Denmark; Depression; Depressive Disorder; Female; H

2015
Different adaptations of Chinese winter-over expeditioners during prolonged Antarctic and sub-Antarctic residence.
    International journal of biometeorology, 2016, Volume: 60, Issue:5

    Topics: Adaptation, Physiological; Adult; Affect; Anger; Antarctic Regions; Asian People; Depression; Dopami

2016
Type 2 Deiodinase Disruption in Astrocytes Results in Anxiety-Depressive-Like Behavior in Male Mice.
    Endocrinology, 2016, Volume: 157, Issue:9

    Topics: Animals; Anxiety; Astrocytes; Depression; Gene Expression; Hindlimb Suspension; Hippocampus; Iodide

2016
The Effect of Congenital and Postnatal Hypothyroidism on Depression-Like Behaviors in Juvenile Rats.
    Journal of clinical research in pediatric endocrinology, 2016, 12-01, Volume: 8, Issue:4

    Topics: Analysis of Variance; Animals; Animals, Newborn; Body Weight; Congenital Hypothyroidism; Depression;

2016
Differences in Brain Glucose Metabolism During Preparation for
    Thyroid : official journal of the American Thyroid Association, 2017, Volume: 27, Issue:1

    Topics: Adult; Affect; Anxiety; Brain; Cognition; Cross-Sectional Studies; Depression; Female; Fluorodeoxygl

2017
The thyroid hormone, triiodothyronine, enhances fluoxetine-induced neurogenesis in rats: possible role in antidepressant-augmenting properties.
    The international journal of neuropsychopharmacology, 2010, Volume: 13, Issue:5

    Topics: Animals; Antidepressive Agents; Depression; Doublecortin Protein; Drug Synergism; Drug Therapy, Comb

2010
Do thyroid hormones mediate the effects of starvation on mood in adolescent girls with eating disorders?
    Psychoneuroendocrinology, 2010, Volume: 35, Issue:10

    Topics: Adolescent; Affect; Body Mass Index; Body Weight; Depression; Feeding and Eating Disorders; Female;

2010
Increased depressive behaviour in mice harboring the mutant thyroid hormone receptor alpha 1.
    Behavioural brain research, 2010, Dec-25, Volume: 214, Issue:2

    Topics: Animals; Anxiety; Behavior, Animal; Depression; Disease Models, Animal; Female; Heterozygote; Hormon

2010
Prevalence of depression in patients affected by subclinical hypothyroidism.
    Panminerva medica, 2010, Volume: 52, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Asymptomatic Diseases; Autoantibodies; Biomarkers; Chi-Square Distri

2010
Thyroid hormones and cognitive functioning in healthy, euthyroid women: a correlational study.
    Hormones and behavior, 2012, Volume: 61, Issue:4

    Topics: Adult; Affect; Aged; Arousal; Attention; Cognition; Depression; Executive Function; Female; Humans;

2012
Depression of the serum cholesterol level by triiodothyropropionic acid.
    The Journal of clinical endocrinology and metabolism, 1959, Volume: 19, Issue:4

    Topics: Cholesterol; Depression; Depressive Disorder; Triiodothyronine

1959
Relationship of stressful life events, anxiety and depression to hyperthyroidism in an asian population.
    Hormone research, 2003, Volume: 60, Issue:5

    Topics: Adult; Anxiety; Case-Control Studies; Depression; Female; Humans; Hyperthyroidism; Life Change Event

2003
Thyroid status, disability and cognitive function, and survival in old age.
    JAMA, 2004, Dec-01, Volume: 292, Issue:21

    Topics: Activities of Daily Living; Aged; Aged, 80 and over; Cognition Disorders; Depression; Disabled Perso

2004
Red blood cell triiodothyronine uptake as membrane parameter of depression.
    Physiological research, 2006, Volume: 55, Issue:2

    Topics: Adult; Antidepressive Agents; Case-Control Studies; Citalopram; Depression; Erythrocyte Membrane; Fe

2006
Sex-dependent effects of fluoxetine and triiodothyronine in the forced swim test in rats.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2006, Volume: 16, Issue:2

    Topics: Animals; Antidepressive Agents, Second-Generation; Depression; Female; Fluoxetine; Male; Motor Activ

2006
Acquired hypothyroidism after switching from thyroid USP to levothyroxine.
    Clinical cornerstone, 2005, Volume: 7 Suppl 2

    Topics: Depression; Drug Therapy, Combination; Fatigue; Female; Hormone Replacement Therapy; Humans; Hypothy

2005
[Thyroid function, activities of daily living and survival in extreme old age: the 'Leiden 85-plus Study'].
    Nederlands tijdschrift voor geneeskunde, 2006, Jan-14, Volume: 150, Issue:2

    Topics: Activities of Daily Living; Aged, 80 and over; Cognition Disorders; Depression; Disabled Persons; Fe

2006
Icariin from Epimedium brevicornum attenuates chronic mild stress-induced behavioral and neuroendocrinological alterations in male Wistar rats.
    Pharmacology, biochemistry, and behavior, 2007, Volume: 87, Issue:1

    Topics: Adrenocorticotropic Hormone; Animals; Behavior, Animal; Body Weight; Brain Chemistry; Chronic Diseas

2007
Thyrotropin serum concentrations in healthy volunteers are associated with depression-related personality traits.
    Neuropsychobiology, 2007, Volume: 56, Issue:2-3

    Topics: Adolescent; Adult; Aged; Depression; Female; Humans; Male; Middle Aged; Personality; Personality Inv

2007
Increase in depression symptoms with weight loss: association with glucose homeostasis and thyroid function.
    Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme, 2008, Volume: 33, Issue:1

    Topics: Adult; Blood Glucose; Depression; Diet, Reducing; Glucose Tolerance Test; Homeostasis; Humans; Male;

2008
Thyrotropin releasing hormone (TRH): a useful tool for psychoneuroendocrine investigation.
    Psychoneuroendocrinology, 1980, Volume: 5, Issue:1

    Topics: Adult; Alcoholism; Depression; Endocrine Glands; Female; Growth Hormone; Humans; Male; Middle Aged;

1980
Thyroid status and the depressed elderly.
    Journal of the American Geriatrics Society, 1980, Volume: 28, Issue:10

    Topics: Aged; Aging; Catecholamines; Depression; Humans; Thyroid Gland; Thyroid Hormones; Thyrotropin; Thyro

1980
Altered serum levels of thyroxine, triiodothyronines and diiodothyronines in endogenous depression.
    Acta endocrinologica, 1981, Volume: 96, Issue:2

    Topics: Depression; Diiodothyronines; Electroconvulsive Therapy; Female; Humans; Male; Thyroid Hormones; Thy

1981
[Diagnostic problems of hyperthyroidism in the older age group (author's transl)].
    Deutsche medizinische Wochenschrift (1946), 1981, Jul-31, Volume: 106, Issue:31-32

    Topics: Age Factors; Aged; Body Weight; Depression; Dyspnea; Female; Humans; Hyperthyroidism; Male; Middle A

1981
Serum 3'-monoiodothyronine levels in normal subjects and in patients with thyroid and non-thyroid disease.
    Acta endocrinologica, 1981, Volume: 97, Issue:4

    Topics: Adult; Depression; Female; Humans; Hyperthyroidism; Hypothyroidism; Kidney Failure, Chronic; Male; M

1981
Triiodothyronine, imipramine, and depression.
    The American journal of psychiatry, 1980, Volume: 137, Issue:3

    Topics: Depression; Drug Therapy, Combination; Female; Humans; Imipramine; Male; Triiodothyronine

1980
T3 toxicosis presented by depression in an elderly woman.
    Postgraduate medical journal, 1980, Volume: 56, Issue:657

    Topics: Aged; Depression; Female; Humans; Hyperthyroidism; Triiodothyronine

1980
[Treatment of refractory primary depression].
    Nederlands tijdschrift voor geneeskunde, 1997, Jul-12, Volume: 141, Issue:28

    Topics: Antidepressive Agents, Tricyclic; Chemotherapy, Adjuvant; Depression; Drug Therapy, Combination; Hum

1997
Psychopathological and cognitive features in subclinical hypothyroidism.
    Progress in neuro-psychopharmacology & biological psychiatry, 1997, Volume: 21, Issue:6

    Topics: Adult; Aged; Anxiety; Brief Psychiatric Rating Scale; Cognition Disorders; Depression; Female; Goite

1997
Different effects of pyridostigmine on the thyrotropin response to thyrotropin-releasing hormone in endogenous depression and subclinical thyrotoxicosis.
    Metabolism: clinical and experimental, 1998, Volume: 47, Issue:1

    Topics: Adult; Cholinesterase Inhibitors; Depression; Diagnosis, Differential; Humans; Male; Pyridostigmine

1998
[Changes in therapy-resistant primary depression].
    Nederlands tijdschrift voor geneeskunde, 1997, Aug-30, Volume: 141, Issue:35

    Topics: Depression; Humans; Hypothyroidism; Triiodothyronine

1997
Circannual pattern of hypothalamic-pituitary-thyroid (HPT) function and mood during extended antarctic residence.
    Psychoneuroendocrinology, 2001, Volume: 26, Issue:4

    Topics: Adult; Affect; Anger; Antarctic Regions; Confusion; Depression; Fatigue; Female; Humans; Hypothalamu

2001
Thyroid hormone in depression.
    Australian family physician, 2001, Volume: 30, Issue:3

    Topics: Depression; Humans; Triiodothyronine

2001
Paradoxical hormonal and behavioral responses to hypothyroid and hyperthyroid states in the Wistar-Kyoto rat.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2001, Volume: 24, Issue:6

    Topics: Animals; Antidepressive Agents; Behavior, Animal; Depression; Hormones; Hyperthyroidism; Hypothalamo

2001
Altered hormone levels and circadian rhythm of activity in the WKY rat, a putative animal model of depression.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2001, Volume: 281, Issue:3

    Topics: Activity Cycles; Adrenocorticotropic Hormone; Animals; Behavior, Animal; Chronobiology Disorders; Co

2001
Triiodothyronine augmentation for the treatment of depression in substance misusers unresponsive to tricyclic antidepressants.
    Hong Kong medical journal = Xianggang yi xue za zhi, 2001, Volume: 7, Issue:3

    Topics: Adolescent; Adult; Antidepressive Agents; Antidepressive Agents, Tricyclic; Depression; Female; Huma

2001
Clinical and experimental studies on the pathogenesis of depression.
    Psychoneuroendocrinology, 1977, Volume: 2, Issue:2

    Topics: Adult; Animals; Brain; Depression; Disease Models, Animal; Female; Histocytochemistry; Humans; Hypot

1977
Thyrotrophin-releasing hormone (TRH) stimulation test in manic-depressive illness.
    Archives of general psychiatry, 1978, Volume: 35, Issue:8

    Topics: Adjustment Disorders; Adult; Age Factors; Aged; Biperiden; Bipolar Disorder; Depression; Female; Hal

1978
Combined therapy of T3, and antidepressants in depression.
    The Journal of international medical research, 1979, Volume: 7, Issue:2

    Topics: Adolescent; Adult; Antidepressive Agents; Depression; Drug Therapy, Combination; Female; Humans; Mal

1979
[Biochemistry of depression].
    Psychiatrie, Neurologie, und medizinische Psychologie, 1976, Volume: 28, Issue:2

    Topics: Adrenocorticotropic Hormone; Bipolar Disorder; Contraceptives, Oral; Cyclic AMP; Depression; Dopamin

1976
Effects of triiodothyronine on drug levels and cardiac function in depressed patients treated with imipramine.
    The American journal of psychiatry, 1979, Volume: 136, Issue:7

    Topics: Adult; Depression; Desipramine; Female; Heart Conduction System; Heart Rate; Humans; Imipramine; Mid

1979
Non-specificity of "behavioral despair" as an animal model of depression.
    European journal of pharmacology, 1979, Dec-07, Volume: 60, Issue:2-3

    Topics: Animals; Antidepressive Agents; Behavior, Animal; Depression; Disease Models, Animal; Female; Humans

1979
Effect of increased iodide intake on thyroid function in subjects on chronic lithium therapy.
    Acta endocrinologica, 1977, Volume: 84, Issue:2

    Topics: Adult; Aged; Depression; Female; Humans; Iodides; Lithium; Male; Middle Aged; Potassium Iodide; Thyr

1977
Prognostic value of thyrotropin-releasing hormone stimulation test in endogenous depression.
    Acta psychiatrica Scandinavica, 1975, Volume: 52, Issue:3

    Topics: Adult; Aged; Depression; Evaluation Studies as Topic; Female; Humans; Male; Middle Aged; Prognosis;

1975
Myxedematous madness without myxedema. Selective defect of TSH release on TRF loading in a young woman with a history of severe depressive illness cured with thryoid hormone replacement therapy.
    Acta medica Scandinavica, 1976, Volume: 199, Issue:3

    Topics: Adolescent; Adult; Depression; Female; Humans; Hypopituitarism; Imipramine; Iodine; Pituitary Gland;

1976
[Progressive exhaustion of the psychotropic effect of T.R.H. Clinical and neuroendocrinologic study].
    Annales medico-psychologiques, 1976, Volume: 2, Issue:2

    Topics: Adult; Depression; Humans; Male; Thyrotropin; Thyrotropin-Releasing Hormone; Thyroxine; Triiodothyro

1976
Cerebrospinal fluid amine metabolites after combined amitriptyline-triiodothyronine treatment of depressed women.
    European journal of clinical pharmacology, 1977, Apr-20, Volume: 11, Issue:4

    Topics: Adult; Amitriptyline; Biogenic Amines; Depression; Drug Therapy, Combination; Female; Homovanillic A

1977
[The use of triiodothyronine in the treatment of depression].
    Orvosi hetilap, 1975, Oct-26, Volume: 116, Issue:43

    Topics: Depression; Female; Humans; Triiodothyronine

1975
Problems of polypharmacy in depression.
    Diseases of the nervous system, 1976, Volume: 37, Issue:3 PT 2

    Topics: Antidepressive Agents; Antidepressive Agents, Tricyclic; Depression; Drug Therapy, Combination; Huma

1976
The possible etiological role of psychological disturbances in Graves' disease.
    Acta medica Austriaca, 1992, Volume: 19 Suppl 1

    Topics: Adult; Anxiety; Autoantibodies; CD4-CD8 Ratio; Depression; Female; Graves Disease; Humans; Leukocyte

1992
Effects of TRH and prolactin in the behavioral despair (swim) model of depression in rats.
    Psychoneuroendocrinology, 1990, Volume: 15, Issue:5-6

    Topics: Aging; Animals; Behavior, Animal; Depression; Desipramine; Injections, Intraventricular; Injections,

1990
The decreased availability of L-tryptophan in depressed females: clinical and biological correlates.
    Progress in neuro-psychopharmacology & biological psychiatry, 1990, Volume: 14, Issue:6

    Topics: Adrenocorticotropic Hormone; Adult; Amino Acids; Analysis of Variance; Depression; Depressive Disord

1990
[Studies on the factors affecting serum thyrotropin levels in healthy controls and on the thyroid function in depressed patients using a highly sensitive immunoassay].
    Nihon Naibunpi Gakkai zasshi, 1990, Oct-20, Volume: 66, Issue:10

    Topics: Adult; Aged; Circadian Rhythm; Depression; Female; Fluoroimmunoassay; Humans; Male; Middle Aged; Ref

1990
Serum thyrotropin in hospitalized psychiatric patients: evidence for hyperthyrotropinemia as measured by an ultrasensitive thyrotropin assay.
    Metabolism: clinical and experimental, 1990, Volume: 39, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Bipolar Disorder; Dementia; Depression; Female; Humans; Male; Mental

1990
Depression. Management tips for the primary care physician.
    Postgraduate medicine, 1988, Feb-01, Volume: 83, Issue:2

    Topics: Antidepressive Agents, Tricyclic; Depression; Humans; Lithium; Monoamine Oxidase Inhibitors; Primary

1988
[Hormonal profile of depressed patients].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1987, Volume: 87, Issue:4

    Topics: Adult; Aged; Bipolar Disorder; Depression; Female; Growth Hormone; Hormones; Humans; Hydrocortisone;

1987
Pharmacological strategies in depression.
    British journal of hospital medicine, 1985, Volume: 34, Issue:3

    Topics: Antidepressive Agents, Tricyclic; Carbamazepine; Depression; Drug Administration Schedule; Drug Ther

1985
Letter: Thyrotropin-releasing hormone and depression.
    Lancet (London, England), 1974, Sep-21, Volume: 2, Issue:7882

    Topics: Adult; Aged; Depression; Female; Humans; Injections, Intravenous; Male; Middle Aged; Thyroid Functio

1974
The quantitative relationship between anxiety-depressive states and the triiodothyronine I-131 binding capacity of alpha and beta globulins--a biochemical test and graphic index for investigation of protein-hormonal physiology in psychiatric disorders.
    Journal of psychiatric research, 1968, Volume: 6, Issue:2

    Topics: Adolescent; Adult; Aged; Alpha-Globulins; Anxiety; Beta-Globulins; Blood Protein Electrophoresis; De

1968
Thyrotropin responses to TRH in depressive illness: relation to clinical subtypes and prolonged duration of depressive episode.
    Folia psychiatrica et neurologica japonica, 1974, Volume: 28, Issue:4

    Topics: Adjustment Disorders; Adolescent; Adult; Aged; Bipolar Disorder; Depression; Depressive Disorder, Ma

1974
Selecting the optimum oral contraceptive.
    The Journal of reproductive medicine, 1973, Volume: 11, Issue:4

    Topics: Acne Vulgaris; Blood Coagulation Disorders; Brain Edema; Breast; Candidiasis; Capillaries; Carbohydr

1973
Combined thyroid (triiodothyronine)-tricyclic antidepressant treatment in depressive states.
    Folia psychiatrica et neurologica japonica, 1974, Volume: 28, Issue:3

    Topics: Adjustment Disorders; Adult; Amitriptyline; Antidepressive Agents; Anxiety; Bipolar Disorder; Blood

1974
Treatment of depression "C" thyroid shock.
    The Journal of the Egyptian Medical Association, 1972, Volume: 55, Issue:7

    Topics: Convulsive Therapy; Depression; Electrocardiography; Humans; Male; Thyroid Hormones; Triiodothyronin

1972
Thyroid-imipramine clinical and chemical interaction: evidence for a receptor deficit in depression.
    Journal of psychiatric research, 1972, Volume: 9, Issue:3

    Topics: Adult; Catechols; Depression; Female; Glycols; Humans; Hydroxyindoleacetic Acid; Imipramine; Middle

1972
Caution in thyroid therapy.
    The New England journal of medicine, 1970, Jul-23, Volume: 283, Issue:4

    Topics: Age Factors; Aged; Depression; Heart Diseases; Humans; Hypothyroidism; Middle Aged; Myxedema; Triiod

1970
Caution in thyroid therapy.
    The New England journal of medicine, 1970, Jul-23, Volume: 283, Issue:4

    Topics: Age Factors; Aged; Depression; Heart Diseases; Humans; Hypothyroidism; Middle Aged; Myxedema; Triiod

1970
Enhancement of imipramine by thyroid stimulating hormone: clinical and theoretical implications.
    The American journal of psychiatry, 1970, Volume: 127, Issue:2

    Topics: Adult; Depression; Drug Synergism; Female; Humans; Imipramine; Male; Middle Aged; Psychiatric Status

1970