Page last updated: 2024-11-02

pentoxifylline and Depression

pentoxifylline has been researched along with Depression in 5 studies

Depression: Depressive states usually of moderate intensity in contrast with MAJOR DEPRESSIVE DISORDER present in neurotic and psychotic disorders.

Research Excerpts

ExcerptRelevanceReference
" Additionally, the effects of chronic administration of the tricyclic antidepressant imipramine and the anti-TNF-α pentoxyphylline were investigated."5.40Lipopolysaccharide repeated challenge followed by chronic mild stress protocol introduces a combined model of depression in rats: reversibility by imipramine and pentoxifylline. ( Abd-Alkhalek, HA; Abdel-tawab, AM; Aboul-Fotouh, S; El Tabbal, M; Elgarf, AS; Farrag, KA; Hammouda, GA; Hassan, AN; Kassim, SK, 2014)
" We hypothesized that inhibition of neuroinflammation by the PIC synthesis inhibitor, pentoxifylline (PTX) would prevent depression-like behaviors induced by heart failure (HF) post-MI in OVX female rats."3.91Role of Myocardial Infarction-Induced Neuroinflammation for Depression-Like Behavior and Heart Failure in Ovariectomized Female Rats. ( Ahmad, M; Lagace, D; Leenen, FHH; Najjar, F, 2019)
" Additionally, the effects of chronic administration of the tricyclic antidepressant imipramine and the anti-TNF-α pentoxyphylline were investigated."1.40Lipopolysaccharide repeated challenge followed by chronic mild stress protocol introduces a combined model of depression in rats: reversibility by imipramine and pentoxifylline. ( Abd-Alkhalek, HA; Abdel-tawab, AM; Aboul-Fotouh, S; El Tabbal, M; Elgarf, AS; Farrag, KA; Hammouda, GA; Hassan, AN; Kassim, SK, 2014)
"cruzi-induced depression is independent of active or prior CNS inflammation."1.38Trypanosoma cruzi-induced depressive-like behavior is independent of meningoencephalitis but responsive to parasiticide and TNF-targeted therapeutic interventions. ( de Almeida, LR; de Souza, AS; Lannes-Vieira, J; Moreira, OC; Pereira, IR; Rocha, MS; Silva, AA; Silva, RR; Vilar-Pereira, G, 2012)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (60.00)24.3611
2020's2 (40.00)2.80

Authors

AuthorsStudies
Yasrebi, SO1
Momtazmanesh, S1
Moghaddam, HS1
Shahmansouri, N1
Mehrpooya, M1
Arbabi, M1
Ghazizadeh-Hashemi, F1
Akhondzadeh, S1
Uzzan, S1
Azab, AN1
Najjar, F1
Ahmad, M1
Lagace, D1
Leenen, FHH1
Elgarf, AS1
Aboul-Fotouh, S1
Abd-Alkhalek, HA1
El Tabbal, M1
Hassan, AN1
Kassim, SK1
Hammouda, GA1
Farrag, KA1
Abdel-tawab, AM1
Vilar-Pereira, G1
Silva, AA1
Pereira, IR1
Silva, RR1
Moreira, OC1
de Almeida, LR1
de Souza, AS1
Rocha, MS1
Lannes-Vieira, J1

Reviews

1 review available for pentoxifylline and Depression

ArticleYear
Anti-TNF-α Compounds as a Treatment for Depression.
    Molecules (Basel, Switzerland), 2021, Apr-19, Volume: 26, Issue:8

    Topics: Bipolar Disorder; Depression; Female; Humans; Inflammation; Male; Pentoxifylline; Tumor Necrosis Fac

2021

Trials

1 trial available for pentoxifylline and Depression

ArticleYear
Pentoxifylline for treatment of major depression after percutaneous coronary intervention or coronary artery bypass grafting: A randomized, double-blind, placebo-controlled trial.
    Journal of psychosomatic research, 2021, Volume: 150

    Topics: Coronary Artery Bypass; Depression; Depressive Disorder, Major; Double-Blind Method; Humans; Iran; P

2021

Other Studies

3 other studies available for pentoxifylline and Depression

ArticleYear
Role of Myocardial Infarction-Induced Neuroinflammation for Depression-Like Behavior and Heart Failure in Ovariectomized Female Rats.
    Neuroscience, 2019, 09-01, Volume: 415

    Topics: Animals; Behavior Rating Scale; Brain-Derived Neurotrophic Factor; Cytokines; Depression; Disease Mo

2019
Lipopolysaccharide repeated challenge followed by chronic mild stress protocol introduces a combined model of depression in rats: reversibility by imipramine and pentoxifylline.
    Pharmacology, biochemistry, and behavior, 2014, Volume: 126

    Topics: Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Corticosterone; Depression; Disease Mod

2014
Trypanosoma cruzi-induced depressive-like behavior is independent of meningoencephalitis but responsive to parasiticide and TNF-targeted therapeutic interventions.
    Brain, behavior, and immunity, 2012, Volume: 26, Issue:7

    Topics: Animals; Antidepressive Agents, Second-Generation; Chagas Disease; Depression; Emotions; Exploratory

2012