protriptyline has been researched along with Depression in 18 studies
Protriptyline: Tricyclic antidepressant similar in action and side effects to IMIPRAMINE. It may produce excitation.
Depression: Depressive states usually of moderate intensity in contrast with MAJOR DEPRESSIVE DISORDER present in neurotic and psychotic disorders.
| Excerpt | Relevance | Reference |
|---|---|---|
| " After 3 1/2 weeks treatment at dosage levels of 40 mg/day, protriptyline plasma levels ranged from 430 to 1430 nmol/l." | 1.26 | Pharmacokinetic aspects of protriptyline plasma levels. ( MacDonald, AJ; Moody, JP; Naylor, GJ; Whyte, SF, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 17 (94.44) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (5.56) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhao, Z | 1 |
| Zhang, HT | 1 |
| Bootzin, E | 1 |
| Millan, MJ | 1 |
| O'Donnell, JM | 1 |
| VAISBERG, M | 1 |
| KRAKOWSKI, AJ | 1 |
| ARNOLD, OH | 1 |
| KRYSPIN-EXNER, K | 1 |
| Amsterdam, J | 1 |
| Brunswick, D | 1 |
| Mendels, J | 1 |
| Marshall, JB | 1 |
| Forker, AD | 1 |
| Hollister, LE | 1 |
| Biggs, JT | 2 |
| Ziegler, VE | 1 |
| Hullin, RP | 1 |
| Fielding, S | 1 |
| Binks, SM | 1 |
| Murchie, JK | 1 |
| Greenwood, DT | 1 |
| Risch, SC | 1 |
| Huey, LY | 1 |
| Janowsky, DS | 1 |
| Moody, JP | 2 |
| Whyte, SF | 2 |
| MacDonald, AJ | 2 |
| Naylor, GJ | 2 |
| Hallstrom, CO | 1 |
| Rees, WL | 1 |
| Pare, CM | 1 |
| Trenchard, A | 1 |
| Turner, P | 1 |
| Holland, WH | 1 |
| Sherman, WR | 1 |
| Priest, RG | 1 |
| Cunha, UV | 1 |
4 reviews available for protriptyline and Depression
| Article | Year |
|---|---|
The clinical application of tricyclic antidepressant pharmacokinetics and plasma levels.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Depression; Desipramine; Doxepin; Heart; Humans; Im | 1980 |
Cardiovascular effects of tricyclic antidepressant drugs: therapeutic usage, overdose, and management of complications.
Topics: Adult; Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Cardiovascular S | 1982 |
Tricyclic antidepressants (first of two parts).
Topics: Aged; Amines; Amitriptyline; Antidepressive Agents, Tricyclic; Chemical Phenomena; Chemistry; Child; | 1978 |
Blood levels of tricyclic antidepressant drugs: assay procedures, reproducibility and relationship to therapeutic outcome and side effects.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Clinical Trials as Topic; Depression; Double-Blind | 1977 |
3 trials available for protriptyline and Depression
| Article | Year |
|---|---|
Protriptyline plasma levels and antidepressant response.
Topics: Adult; Aged; Biopharmaceutics; Clinical Trials as Topic; Depression; Dibenzocycloheptenes; Drug Eval | 1977 |
Blood levels of tricyclic antidepressant drugs: assay procedures, reproducibility and relationship to therapeutic outcome and side effects.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Clinical Trials as Topic; Depression; Double-Blind | 1977 |
Hostility, somatic symptoms and recovery with antidepressants.
Topics: Depression; Dibenzocycloheptenes; Hostility; Humans; Nortriptyline; Personality Inventory; Protripty | 1975 |
12 other studies available for protriptyline and Depression
| Article | Year |
|---|---|
Association of changes in norepinephrine and serotonin transporter expression with the long-term behavioral effects of antidepressant drugs.
Topics: Animals; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Brain; Cyclohex | 2009 |
PROTRIPTYLINE IN THE TREATMENT OF DEPRESSIVE STATES.
Topics: Antidepressive Agents; Bipolar Disorder; Depression; Depressive Disorder; Depressive Disorder, Major | 1964 |
PROTRIPTYLINE IN TREATMENT OF SEVERE DEPRESSIONS A LONG-RANGE PILOT STUDY.
Topics: Antidepressive Agents; Depression; Depressive Disorder; Depressive Disorder, Major; Drug Therapy; Pi | 1965 |
[CLINICAL EXPERIENCES WITH THE ANTIDEPRESSIVE PROTRIPTYLINE (MK 240)].
Topics: Antidepressive Agents; Depression; Depressive Disorder; Drug Therapy; Hypochondriasis; Mental Disord | 1964 |
Tricyclics in elderly patients.
Topics: Aged; Dementia; Depression; Dibenzocycloheptenes; Humans; Protriptyline | 1979 |
A reward-reduction model of depression using self stimulating rats: an appraisal.
Topics: Amphetamine; Animals; Depression; Disease Models, Animal; Humans; Imipramine; Male; Protriptyline; R | 1979 |
Plasma levels of tricyclic antidepressants and clinical efficacy: review of the literature -- part II.
Topics: Antidepressive Agents, Tricyclic; Biotransformation; Clomipramine; Depression; Desipramine; Dibenzoc | 1979 |
Pharmacokinetic aspects of protriptyline plasma levels.
Topics: Administration, Oral; Adolescent; Adult; Aged; Depression; Dibenzocycloheptenes; Drug Interactions; | 1977 |
Platelet uptake of 5-hydroxytryptamine and dopamine in depression.
Topics: Blood Platelets; Clomipramine; Depression; Dopamine; Humans; Protriptyline; Serotonin | 1976 |
Steady-state protriptyline levels in an outpatient population.
Topics: Administration, Oral; Ambulatory Care; Depression; Dibenzocycloheptenes; Humans; Hydroxylation; Live | 1975 |
Plasma concentrations of protriptyline and clinical effects in depressed women.
Topics: Adjustment Disorders; Administration, Oral; Adolescent; Adult; Aged; Amobarbital; Depression; Dibenz | 1976 |
Antidepressants: their uses in nonpsychiatric disorders of aging.
Topics: Affective Symptoms; Aged; Antidepressive Agents; Chronic Disease; Colonic Diseases, Functional; Depr | 1986 |