verapamil has been researched along with Depression in 8 studies
Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.
Depression: Depressive states usually of moderate intensity in contrast with MAJOR DEPRESSIVE DISORDER present in neurotic and psychotic disorders.
| Excerpt | Relevance | Reference |
|---|---|---|
| "When antihypertensive treatment options are clinically equivalent, prescribers may first consider using a verapamil SR-based strategy, especially in patients with CAD who have no history of depression." | 5.12 | Depressive symptoms in coronary artery disease patients after hypertension treatment. ( Lopez, LM; Pepine, CJ; Ried, LD; Sauer, BC; Taylor, MD; Tueth, MJ, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (37.50) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (37.50) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Salgin-Goksen, U | 1 |
| Telli, G | 1 |
| Erikci, A | 1 |
| Dedecengiz, E | 1 |
| Tel, BC | 1 |
| Kaynak, FB | 1 |
| Yelekci, K | 1 |
| Ucar, G | 1 |
| Gokhan-Kelekci, N | 1 |
| Yu, H | 1 |
| Li, M | 1 |
| Shen, X | 1 |
| Lv, D | 1 |
| Sun, X | 1 |
| Wang, J | 1 |
| Gu, X | 1 |
| Hu, J | 1 |
| Wang, C | 1 |
| Capasso, R | 1 |
| Borrelli, F | 1 |
| Capasso, F | 1 |
| Mascolo, N | 1 |
| Izzo, AA | 1 |
| Ried, LD | 1 |
| Tueth, MJ | 1 |
| Taylor, MD | 1 |
| Sauer, BC | 1 |
| Lopez, LM | 1 |
| Pepine, CJ | 1 |
| Srivastava, SK | 1 |
| Nath, C | 1 |
| Price, WA | 1 |
| Shalley, JE | 1 |
| Geoffroy, M | 1 |
| Mogilnicka, E | 1 |
| Nielsen, M | 1 |
| Rafaelsen, OJ | 1 |
| Fogelman, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| INternational VErapamil SR Trandolapril STudy[NCT00133692] | Phase 4 | 22,000 participants | Interventional | 1997-09-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for verapamil and Depression
| Article | Year |
|---|---|
Depressive symptoms in coronary artery disease patients after hypertension treatment.
Topics: Aged; Antihypertensive Agents; Atenolol; Coronary Artery Disease; Depression; Female; Humans; Male; | 2006 |
7 other studies available for verapamil and Depression
| Article | Year |
|---|---|
New 2-Pyrazoline and Hydrazone Derivatives as Potent and Selective Monoamine Oxidase A Inhibitors.
Topics: Animals; Antidepressive Agents; Depression; Hep G2 Cells; Humans; Hydrazones; Mice; Molecular Dockin | 2021 |
The Requirement of L-Type Voltage-Dependent Calcium Channel (L-VDCC) in the Rapid-Acting Antidepressant-Like Effects of Scopolamine in Mice.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Brain-Derived Neurotrophic Factor; Calcium Channel | 2018 |
Inhibitory effect of the antidepressant St. John's wort (hypericum perforatum) on rat bladder contractility in vitro.
Topics: Acetylcholine; Adenosine Triphosphate; Animals; Anthracenes; Antidepressive Agents; Atropine; Bridge | 2004 |
The differential effects of calcium channel blockers in the behavioural despair test in mice.
Topics: Animals; Antidepressive Agents; Calcium Channel Blockers; Clomipramine; Clonidine; Cyproheptadine; D | 2000 |
Lithium-verapamil toxicity in the elderly.
Topics: Aged; Depression; Drug Interactions; Female; Humans; Lithium; Lithium Carbonate; Verapamil | 1987 |
Effect of nifedipine on the shuttlebox escape deficit induced by inescapable shock in the rat.
Topics: Animals; Binding Sites; Brain; Depression; Electroshock; Escape Reaction; Imipramine; Kinetics; Male | 1988 |
Verapamil may cause depression, confusion, and impotence.
Topics: Cognition Disorders; Confusion; Depression; Erectile Dysfunction; Humans; Male; Middle Aged; Verapam | 1987 |