Page last updated: 2024-10-19

nitrites and Depression

nitrites has been researched along with Depression in 21 studies

Nitrites: Salts of nitrous acid or compounds containing the group NO2-. The inorganic nitrites of the type MNO2 (where M=metal) are all insoluble, except the alkali nitrites. The organic nitrites may be isomeric, but not identical with the corresponding nitro compounds. (Grant & Hackh's Chemical Dictionary, 5th ed)

Depression: Depressive states usually of moderate intensity in contrast with MAJOR DEPRESSIVE DISORDER present in neurotic and psychotic disorders.

Research Excerpts

ExcerptRelevanceReference
" This study was envisaged to evaluate the ameliorative effect of Curcumin on depression like behavior and cognitive impairment observed in pentylenetetrazole kindled animals."7.79Ameliorative effect of Curcumin on seizure severity, depression like behavior, learning and memory deficit in post-pentylenetetrazole-kindled mice. ( Choudhary, KM; Goel, RK; Mishra, A; Poroikov, VV, 2013)
" Repeated CORT dosing caused depression-like behavior in mice as indicated by increased despair effects in forced swim test (FST) and anhedonia in sucrose preference test."5.42Effect of a novel 5-HT3 receptor antagonist 4i, in corticosterone-induced depression-like behavior and oxidative stress in mice. ( Gupta, D; Kurhe, Y; Radhakrishnan, M, 2015)
"Mangiferin pretreatment significantly ameliorated the anxiety-like behaviour as evident from the results of an elevated plus maze, light-dark box and open field test."5.40Protective effect of mangiferin against lipopolysaccharide-induced depressive and anxiety-like behaviour in mice. ( Baruah, CC; Jangra, A; Lahkar, M; Lukhi, MM; Sulakhiya, K, 2014)
"Honokiol (HNK) is a biphenolic neolignan possessing multiple biological activities including antioxidant, anti-inflammatory, anxiolytic, antidepressant and neuroprotective."5.40Honokiol abrogates lipopolysaccharide-induced depressive like behavior by impeding neuroinflammation and oxido-nitrosative stress in mice. ( Baruah, CC; Dwivedi, S; Hazarika, NK; Jangra, A; Kumar, P; Lahkar, M; Sulakhiya, K, 2014)
"Abrupt discontinuation of chronic amphetamine consumption leads to withdrawal symptoms including depression, anhedonia, dysphoria, fatigue, and anxiety."3.88Involvement of NO/NMDA-R pathway in the behavioral despair induced by amphetamine withdrawal. ( Afshari, K; Amini-Khoei, H; Amiri, S; Dehpour, AR; Ghesmati, M; Haj-Mirzaian, A; Hashemiaghdam, A; Ramezanzadeh, K, 2018)
" However, there is no published report on the effect of pioglitazone as an antidepressant in the treatment of depression induced by neuropathic pain with CCI in rats."3.85Possible modulation of PPAR-γ cascade against depression caused by neuropathic pain in rats. ( Deshmukh, VR; Garg, S; Prasoon, P, 2017)
" This study was envisaged to evaluate the ameliorative effect of Curcumin on depression like behavior and cognitive impairment observed in pentylenetetrazole kindled animals."3.79Ameliorative effect of Curcumin on seizure severity, depression like behavior, learning and memory deficit in post-pentylenetetrazole-kindled mice. ( Choudhary, KM; Goel, RK; Mishra, A; Poroikov, VV, 2013)
"More studies are still warranted in similar rodent models of pain and depression, so, that the present findings can be further substantiated to establish the clinical effectiveness of berberine in a subset of patients suffering from pain as well as depression."3.79Possible involvement of oxido-nitrosative stress induced neuro-inflammatory cascade and monoaminergic pathway: underpinning the correlation between nociceptive and depressive behaviour in a rodent model. ( Arora, V; Chopra, K, 2013)
"Colitis was induced by intrarectal (i."1.43Behavioral despair associated with a mouse model of Crohn's disease: Role of nitric oxide pathway. ( Abbasi, A; Dehpour, AR; Fakhfouri, G; Fakhraei, N; Ghia, JE; Heydarpour, P; Khoshkish, S; Rahimian, R; Salehi-Sadaghiani, M; Wang, H, 2016)
"Depression has been associated with impaired nitric oxide (NO)-mediated vasodilation and vascular dysregulation (VD)."1.43Chronic depression symptoms and salivary NOx are associated with retinal vascular dysregulation: The SABPA study. ( Frasure-Smith, N; Hamer, M; Harvey, BH; Lambert, GW; Malan, L; Malan, NT; Reimann, M; Schlaich, MP; Steyn, F; Vilser, W; von Känel, R, 2016)
"Depression was evaluated in all experimental groups using tail suspension and forced swim test on days 1, 5, 10 and 15, 2h after pentylenetetrazole challenge."1.43Adjuvant indoleamine 2,3-dioxygenase enzyme inhibition for comprehensive management of epilepsy and comorbid depression. ( Goel, RK; Singh, T, 2016)
" Repeated CORT dosing caused depression-like behavior in mice as indicated by increased despair effects in forced swim test (FST) and anhedonia in sucrose preference test."1.42Effect of a novel 5-HT3 receptor antagonist 4i, in corticosterone-induced depression-like behavior and oxidative stress in mice. ( Gupta, D; Kurhe, Y; Radhakrishnan, M, 2015)
"Mangiferin pretreatment significantly ameliorated the anxiety-like behaviour as evident from the results of an elevated plus maze, light-dark box and open field test."1.40Protective effect of mangiferin against lipopolysaccharide-induced depressive and anxiety-like behaviour in mice. ( Baruah, CC; Jangra, A; Lahkar, M; Lukhi, MM; Sulakhiya, K, 2014)
"Honokiol (HNK) is a biphenolic neolignan possessing multiple biological activities including antioxidant, anti-inflammatory, anxiolytic, antidepressant and neuroprotective."1.40Honokiol abrogates lipopolysaccharide-induced depressive like behavior by impeding neuroinflammation and oxido-nitrosative stress in mice. ( Baruah, CC; Dwivedi, S; Hazarika, NK; Jangra, A; Kumar, P; Lahkar, M; Sulakhiya, K, 2014)
"Depression is the most common of all psychiatric disorders and the role of amino acid transmitters in this pathology has been recently studied."1.38Plasma amino acid levels discriminate between control subjects and mildly depressed elderly women. ( Aburto-Arciniega, E; Aguirre-Hernández, R; Cruz-Revilla, C; Guevara-Guzmán, R; Jiménez-Mendoza, A; Mayoral-Mariles, A; Severiano-Pérez, P; Vega-Manriquez, X, 2012)
" Females tended to increase their nitric oxide (NO) levels further, while MDA levels did not reach those of males, thus retaining significantly higher NO bioavailability than in males."1.35Sex differences in oxidant/antioxidant balance under a chronic mild stress regime. ( Chatzigeorgiou, A; Dalla, C; Kamper, EF; Kamper, M; Papadopoulou-Daifoti, Z; Pitychoutis, PM; Tsimpoukidi, O, 2009)

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (4.76)18.2507
2000's2 (9.52)29.6817
2010's15 (71.43)24.3611
2020's3 (14.29)2.80

Authors

AuthorsStudies
Maratha, S1
Sharma, V1
Walia, V1
Omidi-Ardali, H1
Badi, AG1
Saghaei, E1
Amini-Khoei, H3
Lorigooini, Z1
Boroujeni, SN1
Sayyadi-Shahraki, M1
Rahimi-Madiseh, M1
Bijad, E1
Garg, S1
Deshmukh, VR1
Prasoon, P1
Haj-Mirzaian, A3
Amiri, S2
Hashemiaghdam, A1
Ramezanzadeh, K1
Ghesmati, M1
Afshari, K1
Dehpour, AR4
Choudhary, KM1
Mishra, A1
Poroikov, VV1
Goel, RK2
Mello, BS1
Monte, AS1
McIntyre, RS1
Soczynska, JK1
Custódio, CS1
Cordeiro, RC1
Chaves, JH1
Vasconcelos, SM1
Nobre, HV1
Florenço de Sousa, FC1
Hyphantis, TN1
Carvalho, AF1
Macêdo, DS1
Arora, V1
Chopra, K1
Jangra, A2
Lukhi, MM1
Sulakhiya, K2
Baruah, CC2
Lahkar, M2
Kumar, P1
Dwivedi, S1
Hazarika, NK1
Gupta, D1
Radhakrishnan, M1
Kurhe, Y1
Rahimi-Balaei, M1
Razmi, A1
Kordjazy, N1
Shirzadian, A1
Ejtemaei Mehr, S1
Sianati, H1
Heydarpour, P1
Rahimian, R1
Fakhfouri, G1
Khoshkish, S1
Fakhraei, N1
Salehi-Sadaghiani, M1
Wang, H1
Abbasi, A1
Ghia, JE1
Saravi, SS2
Mousavi, SE1
Malan, L1
Hamer, M1
von Känel, R1
Schlaich, MP1
Reimann, M1
Frasure-Smith, N1
Lambert, GW1
Vilser, W1
Harvey, BH1
Steyn, F1
Malan, NT1
Singh, T1
Kamper, EF1
Chatzigeorgiou, A1
Tsimpoukidi, O1
Kamper, M1
Dalla, C1
Pitychoutis, PM1
Papadopoulou-Daifoti, Z1
Chhillar, R1
Dhingra, D1
Mayoral-Mariles, A1
Cruz-Revilla, C1
Vega-Manriquez, X1
Aguirre-Hernández, R1
Severiano-Pérez, P1
Aburto-Arciniega, E1
Jiménez-Mendoza, A1
Guevara-Guzmán, R1
Harmon, D1
Eustace, N1
Ghori, K1
Butler, M1
O'Callaghan, S1
O'Donnell, A1
Moore-Groarke, GM1
Shorten, G1
Strathdee, SA1
Hogg, RS1
Martindale, SL1
Cornelisse, PG1
Craib, KJ1
Montaner, JS1
O'Shaughnessy, MV1
Schechter, MT1

Trials

2 trials available for nitrites and Depression

ArticleYear
Effects of doxycycline on depressive-like behavior in mice after lipopolysaccharide (LPS) administration.
    Journal of psychiatric research, 2013, Volume: 47, Issue:10

    Topics: Animals; Antidepressive Agents; Brain; Brain-Derived Neurotrophic Factor; Depression; Disease Models

2013
Plasma concentrations of nitric oxide products and cognitive dysfunction following coronary artery bypass surgery.
    European journal of anaesthesiology, 2005, Volume: 22, Issue:4

    Topics: Adult; Affect; Aged; Biomarkers; Cardiopulmonary Bypass; Cognition Disorders; Delirium; Depression;

2005

Other Studies

19 other studies available for nitrites and Depression

ArticleYear
Possible involvement of NO-cGMP signaling in the antidepressant like Effect of Amantadine in mice.
    Metabolic brain disease, 2022, Volume: 37, Issue:6

    Topics: Amantadine; Animals; Antidepressive Agents; Cyclic GMP; Depression; Glutamic Acid; Hindlimb Suspensi

2022
Nitric oxide mediates the antidepressant-like effect of modafinil in mouse forced swimming and tail suspension tests.
    Journal of basic and clinical physiology and pharmacology, 2020, Oct-05, Volume: 32, Issue:2

    Topics: Animals; Antidepressive Agents; Arginine; Depression; Hindlimb Suspension; Hippocampus; Mice; Modafi

2020
Limonene through Attenuation of Neuroinflammation and Nitrite Level Exerts Antidepressant-Like Effect on Mouse Model of Maternal Separation Stress.
    Behavioural neurology, 2021, Volume: 2021

    Topics: Animals; Antidepressive Agents; Behavior, Animal; Depression; Disease Models, Animal; Limonene; Mate

2021
Possible modulation of PPAR-γ cascade against depression caused by neuropathic pain in rats.
    Journal of basic and clinical physiology and pharmacology, 2017, Nov-27, Volume: 28, Issue:6

    Topics: Animals; Brain; Catalase; Depression; Dose-Response Relationship, Drug; Glutathione; Immobility Resp

2017
Involvement of NO/NMDA-R pathway in the behavioral despair induced by amphetamine withdrawal.
    Brain research bulletin, 2018, Volume: 139

    Topics: Amphetamine; Analysis of Variance; Animals; Central Nervous System Stimulants; Depression; Disease M

2018
Ameliorative effect of Curcumin on seizure severity, depression like behavior, learning and memory deficit in post-pentylenetetrazole-kindled mice.
    European journal of pharmacology, 2013, Mar-15, Volume: 704, Issue:1-3

    Topics: Acetylcholinesterase; Animals; Anticonvulsants; Behavior, Animal; Brain; Convulsants; Curcumin; Depr

2013
Possible involvement of oxido-nitrosative stress induced neuro-inflammatory cascade and monoaminergic pathway: underpinning the correlation between nociceptive and depressive behaviour in a rodent model.
    Journal of affective disorders, 2013, Volume: 151, Issue:3

    Topics: Animals; Berberine; Caspase 3; Cerebral Cortex; Depression; Disease Models, Animal; Dopamine; Hippoc

2013
Protective effect of mangiferin against lipopolysaccharide-induced depressive and anxiety-like behaviour in mice.
    European journal of pharmacology, 2014, Oct-05, Volume: 740

    Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Antioxidants; Anxiety; Behavior, Animal; Brain-

2014
Honokiol abrogates lipopolysaccharide-induced depressive like behavior by impeding neuroinflammation and oxido-nitrosative stress in mice.
    European journal of pharmacology, 2014, Dec-05, Volume: 744

    Topics: Animals; Antidepressive Agents; Biphenyl Compounds; Brain-Derived Neurotrophic Factor; Corticosteron

2014
Effect of a novel 5-HT3 receptor antagonist 4i, in corticosterone-induced depression-like behavior and oxidative stress in mice.
    Steroids, 2015, Volume: 96

    Topics: Animals; Behavior, Animal; Catalase; Corticosterone; Depression; Glutathione; Hypothalamus; Lipid Pe

2015
Co-occurrence of anxiety and depressive-like behaviors following adolescent social isolation in male mice; possible role of nitrergic system.
    Physiology & behavior, 2015, Jun-01, Volume: 145

    Topics: Animals; Animals, Newborn; Anxiety Disorders; Depression; Disease Models, Animal; Enzyme Inhibitors;

2015
Behavioral despair associated with a mouse model of Crohn's disease: Role of nitric oxide pathway.
    Progress in neuro-psychopharmacology & biological psychiatry, 2016, Jan-04, Volume: 64

    Topics: Animals; Antidepressive Agents; Colitis; Colon; Crohn Disease; Depression; Disease Models, Animal; E

2016
Minocycline Attenuates Depressive-Like Behaviour Induced by Rat Model of Testicular Torsion: Involvement of Nitric Oxide Pathway.
    Basic & clinical pharmacology & toxicology, 2016, Volume: 118, Issue:4

    Topics: Animals; Antidepressive Agents; Behavior, Animal; Cyclic GMP; Depression; Disease Models, Animal; Ma

2016
Chronic depression symptoms and salivary NOx are associated with retinal vascular dysregulation: The SABPA study.
    Nitric oxide : biology and chemistry, 2016, 05-01, Volume: 55-56

    Topics: Black People; Blood Pressure; Depression; Female; Humans; Male; Nitrates; Nitric Oxide; Nitrites; Re

2016
Adjuvant indoleamine 2,3-dioxygenase enzyme inhibition for comprehensive management of epilepsy and comorbid depression.
    European journal of pharmacology, 2016, Aug-05, Volume: 784

    Topics: Animals; Comorbidity; Corticosterone; Depression; Drug Interactions; Enzyme Inhibitors; Epilepsy; Hi

2016
Sex differences in oxidant/antioxidant balance under a chronic mild stress regime.
    Physiology & behavior, 2009, Aug-04, Volume: 98, Issue:1-2

    Topics: Animals; Antioxidants; Chronic Disease; Colorimetry; Depression; Female; Glutathione Peroxidase; Glu

2009
Antidepressant-like activity of gallic acid in mice subjected to unpredictable chronic mild stress.
    Fundamental & clinical pharmacology, 2013, Volume: 27, Issue:4

    Topics: Animals; Antidepressive Agents; Antioxidants; Brain; Catalase; Corticosterone; Depression; Fluoxetin

2013
Plasma amino acid levels discriminate between control subjects and mildly depressed elderly women.
    Archives of medical research, 2012, Volume: 43, Issue:5

    Topics: Aged; Amino Acids; Case-Control Studies; Depression; Female; Humans; Logistic Models; Nitrites; Olfa

2012
Determinants of sexual risk-taking among young HIV-negative gay and bisexual men.
    Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association, 1998, Sep-01, Volume: 19, Issue:1

    Topics: Adult; Age Factors; Bisexuality; Cohort Studies; Cross-Sectional Studies; Depression; Educational St

1998