Assay ID | Title | Year | Journal | Article |
AID748848 | Drug metabolism in mouse liver microsomes assessed as (E)-2,2,2-trifluoro-N-(4-(hydroxymethyl)-2-methylphenyl)-N'-(3-methoxybenzylidene)acetohydrazide retention time at 5 uM by LC/MS/MS analysis | 2013 | Bioorganic & medicinal chemistry, May-15, Volume: 21, Issue:10
| Metabolism of a potent neuroprotective hydrazide. |
AID748865 | Drug metabolism in human liver microsomes assessed as formation of (E)-N-(2,4-dimethylphenyl)-2,2,2-trifluoro-N'-(3-hydroxybenzyli-dene)acetohydrazide at 5 uM by LC/MS/MS analysis | 2013 | Bioorganic & medicinal chemistry, May-15, Volume: 21, Issue:10
| Metabolism of a potent neuroprotective hydrazide. |
AID748853 | Half life in human liver microsomes at 5 uM by LC/MS/MS analysis in presence of NADPH | 2013 | Bioorganic & medicinal chemistry, May-15, Volume: 21, Issue:10
| Metabolism of a potent neuroprotective hydrazide. |
AID748876 | Drug metabolism in mouse liver microsomes assessed as metabolite M5 retention time at 5 uM by LC/MS/MS analysis | 2013 | Bioorganic & medicinal chemistry, May-15, Volume: 21, Issue:10
| Metabolism of a potent neuroprotective hydrazide. |
AID748864 | Drug metabolism in human liver microsomes assessed as formation of (E)-2,2,2-trifluoro-N-(4-(hydroxymethyl)-2-methylphenyl)-N'-(3-methoxybenzylidene)acetohydrazide at 5 uM by LC/MS/MS analysis | 2013 | Bioorganic & medicinal chemistry, May-15, Volume: 21, Issue:10
| Metabolism of a potent neuroprotective hydrazide. |
AID748872 | Drug metabolism in human liver microsomes assessed as formation of 3-methoxy benzaldehyde at 5 uM by LC/MS/MS analysis | 2013 | Bioorganic & medicinal chemistry, May-15, Volume: 21, Issue:10
| Metabolism of a potent neuroprotective hydrazide. |
AID748851 | Drug metabolism in human liver microsomes assessed as retention time at 5 uM by LC/MS/MS analysis | 2013 | Bioorganic & medicinal chemistry, May-15, Volume: 21, Issue:10
| Metabolism of a potent neuroprotective hydrazide. |
AID748862 | Half life in BALB/c mouse blood at 20 mg/kg, iv administered in corn oil by LC/MS/MS analysis | 2013 | Bioorganic & medicinal chemistry, May-15, Volume: 21, Issue:10
| Metabolism of a potent neuroprotective hydrazide. |
AID748863 | Half life in BALB/c mouse brain at 20 mg/kg, iv administered in corn oil by LC/MS/MS analysis | 2013 | Bioorganic & medicinal chemistry, May-15, Volume: 21, Issue:10
| Metabolism of a potent neuroprotective hydrazide. |
AID748861 | Drug metabolism in BALB/c mouse blood assessed as retention time at 20 mg/kg, iv administered in corn oil by LC/MS/MS analysis | 2013 | Bioorganic & medicinal chemistry, May-15, Volume: 21, Issue:10
| Metabolism of a potent neuroprotective hydrazide. |
AID748857 | Neuroprotective activity in rat primary cortical neurons assessed as reduction in trophic factor withdrawal after 2 days by fluorescent live-dead assay | 2013 | Bioorganic & medicinal chemistry, May-15, Volume: 21, Issue:10
| Metabolism of a potent neuroprotective hydrazide. |
AID748873 | Drug metabolism in human liver microsomes assessed as formation of 2,4-dimethylhydrazine at 5 uM by LC/MS/MS analysis | 2013 | Bioorganic & medicinal chemistry, May-15, Volume: 21, Issue:10
| Metabolism of a potent neuroprotective hydrazide. |
AID748849 | Drug metabolism in mouse liver microsomes assessed as (E)-N'-(3,4-dihydroxybenzylidene)-N-(2,4-dimethylphenyl)-2,2,2-trifluoroacetohydrazide retention time at 5 uM by LC/MS/MS analysis | 2013 | Bioorganic & medicinal chemistry, May-15, Volume: 21, Issue:10
| Metabolism of a potent neuroprotective hydrazide. |
AID748854 | Half life in mouse liver microsomes at 5 uM by LC/MS/MS analysis in presence of NADPH | 2013 | Bioorganic & medicinal chemistry, May-15, Volume: 21, Issue:10
| Metabolism of a potent neuroprotective hydrazide. |
AID748874 | Drug metabolism in human liver microsomes assessed as formation of 2,4-dimethylaniline at 5 uM by LC/MS/MS analysis | 2013 | Bioorganic & medicinal chemistry, May-15, Volume: 21, Issue:10
| Metabolism of a potent neuroprotective hydrazide. |
AID748858 | Drug metabolism in BALB/c mouse blood assessed as (E)-N-(2,4-dimethylphenyl)-2,2,2-trifluoro-N'-(3-hydroxybenzyli-dene)acetohydrazide retention time at 20 mg/kg, iv administered in corn oil by LC/MS/MS analysis | 2013 | Bioorganic & medicinal chemistry, May-15, Volume: 21, Issue:10
| Metabolism of a potent neuroprotective hydrazide. |
AID748852 | Drug metabolism in mouse liver microsomes assessed as retention time at 5 uM by LC/MS/MS analysis | 2013 | Bioorganic & medicinal chemistry, May-15, Volume: 21, Issue:10
| Metabolism of a potent neuroprotective hydrazide. |
AID748869 | Drug metabolism in mouse liver microsomes assessed as formation of 3-methoxy benzaldehyde at 5 uM by LC/MS/MS analysis | 2013 | Bioorganic & medicinal chemistry, May-15, Volume: 21, Issue:10
| Metabolism of a potent neuroprotective hydrazide. |
AID748866 | Drug metabolism in mouse plasma assessed as formation of 2,4-dimethylhydrazine at 5 uM by LC/MS/MS analysis | 2013 | Bioorganic & medicinal chemistry, May-15, Volume: 21, Issue:10
| Metabolism of a potent neuroprotective hydrazide. |
AID748860 | Drug metabolism in BALB/c mouse blood assessed as metabolite BM1 retention time at 20 mg/kg, iv administered in corn oil by LC/MS/MS analysis | 2013 | Bioorganic & medicinal chemistry, May-15, Volume: 21, Issue:10
| Metabolism of a potent neuroprotective hydrazide. |
AID748868 | Drug metabolism in mouse plasma assessed as formation of 2,4-dimethylaniline at 5 uM by LC/MS/MS analysis | 2013 | Bioorganic & medicinal chemistry, May-15, Volume: 21, Issue:10
| Metabolism of a potent neuroprotective hydrazide. |
AID748856 | Neuroprotective activity in human MC65 cells expressing C-terminal 99 amino acids from beta secretase assessed as reduction in intracellular amyloid beta toxicity after 4 days by MTT assay | 2013 | Bioorganic & medicinal chemistry, May-15, Volume: 21, Issue:10
| Metabolism of a potent neuroprotective hydrazide. |
AID748859 | Drug metabolism in BALB/c mouse blood assessed as metabolite BM2 retention time at 20 mg/kg, iv administered in corn oil by LC/MS/MS analysis | 2013 | Bioorganic & medicinal chemistry, May-15, Volume: 21, Issue:10
| Metabolism of a potent neuroprotective hydrazide. |
AID748871 | Drug metabolism in mouse liver microsomes assessed as formation of 2,4-dimethylhydrazine at 5 uM by LC/MS/MS analysis | 2013 | Bioorganic & medicinal chemistry, May-15, Volume: 21, Issue:10
| Metabolism of a potent neuroprotective hydrazide. |
AID748850 | Drug metabolism in mouse liver microsomes assessed as (E)-N-(2,4-dimethylphenyl)-2,2,2-trifluoro-N'-(3-hydroxybenzyli-dene)acetohydrazide retention time at 5 uM by LC/MS/MS analysis | 2013 | Bioorganic & medicinal chemistry, May-15, Volume: 21, Issue:10
| Metabolism of a potent neuroprotective hydrazide. |
AID748870 | Drug metabolism in mouse liver microsomes assessed as formation of 2,4-dimethylaniline at 5 uM by LC/MS/MS analysis | 2013 | Bioorganic & medicinal chemistry, May-15, Volume: 21, Issue:10
| Metabolism of a potent neuroprotective hydrazide. |
AID748875 | Drug metabolism in mouse liver microsomes assessed as metabolite M4 retention time at 5 uM by LC/MS/MS analysis | 2013 | Bioorganic & medicinal chemistry, May-15, Volume: 21, Issue:10
| Metabolism of a potent neuroprotective hydrazide. |
AID748867 | Drug metabolism in mouse plasma assessed as formation of 3-methoxy benzaldehyde at 5 uM by LC/MS/MS analysis | 2013 | Bioorganic & medicinal chemistry, May-15, Volume: 21, Issue:10
| Metabolism of a potent neuroprotective hydrazide. |
AID748855 | Neuroprotective activity in mouse HT22 cells assessed as reduction in glutamate-induced oxidative stress incubated for 30 mins prior to glutamate-challenge measured after 24 hrs by MTT assay | 2013 | Bioorganic & medicinal chemistry, May-15, Volume: 21, Issue:10
| Metabolism of a potent neuroprotective hydrazide. |
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |