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pentobarbital and Depression

pentobarbital has been researched along with Depression in 27 studies

Pentobarbital: A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally. It is prescribed more frequently for sleep induction than for sedation but, like similar agents, may lose its effectiveness by the second week of continued administration. (From AMA Drug Evaluations Annual, 1994, p236)
pentobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and sec-pentyl groups.

Depression: Depressive states usually of moderate intensity in contrast with MAJOR DEPRESSIVE DISORDER present in neurotic and psychotic disorders.

Research Excerpts

ExcerptRelevanceReference
" The present study investigated the possible relation between muscimol-induced long-term depression and barbiturates/benzodiazepine-induced amnesia and attempts to determine the possible effect of pregnenolone sulfate on muscimol-induced long-term depression."7.70Potentiation of muscimol-induced long-term depression by benzodiazepines and prevention or reversal by pregnenolone sulfate. ( Akhondzadeh, S; Stone, TW, 1998)
" The present study investigated the possible relation between muscimol-induced long-term depression and barbiturates/benzodiazepine-induced amnesia and attempts to determine the possible effect of pregnenolone sulfate on muscimol-induced long-term depression."3.70Potentiation of muscimol-induced long-term depression by benzodiazepines and prevention or reversal by pregnenolone sulfate. ( Akhondzadeh, S; Stone, TW, 1998)
"Anxiety and depression are often comorbid with neurological as well as other medical maladies."1.56Electronegativity in Substituted-4(H)-quinazolinones Causes Anxiolysis without a Sedative-hypnotic Adverse Reaction in Female Wistar Rats. ( Agarwal, RK; Das, D; Gajbhiye, A; Mishra, S; Patil, S; Sahu, A; Verma, E, 2020)
"Hyperoside was obtained from the aerial parts of H."1.37The anti-immobility effect of hyperoside on the forced swimming test in rats is mediated by the D2-like receptors activation. ( Betti, AH; Haas, JS; Poser, GL; Rates, SM; Schripsema, J; Stein, AC; Stolz, ED, 2011)

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-199019 (70.37)18.7374
1990's1 (3.70)18.2507
2000's1 (3.70)29.6817
2010's5 (18.52)24.3611
2020's1 (3.70)2.80

Authors

AuthorsStudies
Mishra, S1
Das, D1
Sahu, A1
Verma, E1
Patil, S1
Agarwal, RK1
Gajbhiye, A1
Wang, W1
Tan, T1
Yu, Y1
Huang, Z1
Du, Y1
Han, H1
Dong, Z1
Ueno, H1
Suemitsu, S1
Murakami, S1
Kitamura, N1
Wani, K1
Takahashi, Y1
Matsumoto, Y1
Okamoto, M1
Ishihara, T1
Haas, JS1
Stolz, ED1
Betti, AH1
Stein, AC1
Schripsema, J1
Poser, GL1
Rates, SM1
Dhir, A1
Malik, S1
Kessar, SV1
Singh, KN1
Kulkarni, SK1
Luo, J1
Min, S1
Wei, K1
Li, P1
Dong, J1
Liu, YF1
VAN HARREVELD, A1
STAMM, JS1
LARSON, E2
WYNN, MF2
ADAMS, JP2
ROBERTSON, AC1
FOULKS, JG1
DANIEL, EE1
SILA, B1
MOWRER, M1
ULETT, G1
JOHNSON, M1
SHAGASS, C1
SCHWARTZ, M1
KUEBLER, WF1
BENDURE, JD1
HOROVITZ, ZP1
FURGIUELE, AR1
BRANNICK, LJ1
BURKE, JC1
CRAVER, BN1
LISS, L1
SOLZE, DA1
FISCHER, R1
BOEHRINGER, A1
WILKINS, DS1
FEATHERSTONE, RM1
Pickens, RW1
Heston, LL1
Akhondzadeh, S1
Stone, TW1
Moreira, DL1
Souza, PO1
Kaplan, MA1
Pereira, NA1
Cardoso, GL1
Guimarães, EF1
Prange, AJ1
Wilson, IC1
Breese, GR1
Lipton, MA1
Kissin, B1
Gross, MM1
Carranza-Acevedo, J2
Velasco, M2
Hauri, P1
Hawkins, DR1
Greenberg, R1
Pearlman, C1
Vogel, GW1
Traub, AC1
Ben-Horin, P1
Meyers, GM1

Reviews

2 reviews available for pentobarbital and Depression

ArticleYear
Behavioral effects of hypothalamic releasing hormones in animals and men.
    Progress in brain research, 1975, Volume: 42

    Topics: Animals; Behavior; Brain; Child; Depression; Female; Gonadotropin-Releasing Hormone; Humans; Hyperki

1975
Cutting the REM nerve: an approach to the adaptive role of REM sleep.
    Perspectives in biology and medicine, 1974,Summer, Volume: 17, Issue:4

    Topics: Adaptation, Psychological; Animals; Anxiety; Avoidance Learning; Defense Mechanisms; Depression; Ele

1974

Other Studies

25 other studies available for pentobarbital and Depression

ArticleYear
Electronegativity in Substituted-4(H)-quinazolinones Causes Anxiolysis without a Sedative-hypnotic Adverse Reaction in Female Wistar Rats.
    Central nervous system agents in medicinal chemistry, 2020, Volume: 20, Issue:1

    Topics: Animals; Anti-Anxiety Agents; Anxiety; Depression; Female; Hypnotics and Sedatives; Lethal Dose 50;

2020
Inhibition of AMPAR endocytosis alleviates pentobarbital-induced spatial memory deficits and synaptic depression.
    Behavioural brain research, 2018, Feb-26, Volume: 339

    Topics: Animals; Depression; Endocytosis; Hippocampus; Long-Term Potentiation; Male; Memory Disorders; Memor

2018
Behavioural effects of inhalation exposure to dizocilpine (MK-801) in mice.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2019, Volume: 117

    Topics: Animals; Behavior, Animal; Depression; Dizocilpine Maleate; Drug Administration Routes; Imipramine;

2019
The anti-immobility effect of hyperoside on the forced swimming test in rats is mediated by the D2-like receptors activation.
    Planta medica, 2011, Volume: 77, Issue:4

    Topics: Animals; Antidepressive Agents; Behavior, Animal; Brazil; Central Nervous System Depressants; Depres

2011
Evaluation of antidepressant activity of 1-(7-methoxy-2-methyl-1,2,3,4-tetrahydro-isoquinolin-4-YL)-cyclohexanol, a β-substituted phenylethylamine in mice.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2011, Volume: 21, Issue:9

    Topics: Animals; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antipsychotic Agents; Beha

2011
Propofol protects against impairment of learning-memory and imbalance of hippocampal Glu/GABA induced by electroconvulsive shock in depressed rats.
    Journal of anesthesia, 2011, Volume: 25, Issue:5

    Topics: Animals; Cognition; Depression; Down-Regulation; Electroconvulsive Therapy; Electroshock; gamma-Amin

2011
Effect of pentobarbital and ether on the spreading cortical depression.
    The American journal of physiology, 1953, Volume: 173, Issue:1

    Topics: Barbiturates; Cerebral Cortex; Cortical Spreading Depression; Depression; Depressive Disorder; Ether

1953
Studies of pentobarbital depression.
    Anesthesiology, 1954, Volume: 15, Issue:5

    Topics: Barbiturates; Depression; Depressive Disorder; Humans; Pentobarbital; Pentylenetetrazole; Poisoning;

1954
The effects of pentobarbital-induced myocardial depression on cardiac electrolyte distribution.
    The Journal of pharmacology and experimental therapeutics, 1958, Volume: 122, Issue:2

    Topics: Cardiomyopathies; Depression; Electrolytes; Heart; Humans; Myocardium; Pentobarbital

1958
The differentiation of psychiatric patients by EEG changes after sodium pentothal.
    Recent advances in biological psychiatry, 1961, Volume: 4

    Topics: Depression; Depressive Disorder; Electroencephalography; Humans; Pentobarbital; Psychotic Disorders;

1961
NEUROPHYSIOLOGICAL DYSFUNCTION ASSOCIATED WITH SOME PSYCHIATRIC DISORDERS.
    Psychiatric research reports, 1963, Volume: 17

    Topics: Anxiety; Anxiety Disorders; Attention; Cats; Depression; Electroencephalography; Hearing; Humans; Me

1963
THE EFFECT OF DIMEFLINE ON ACUTE CANINE BARBITURATE DEPRESSION.
    American journal of veterinary research, 1963, Volume: 24

    Topics: Anesthesia; Anesthesia, General; Animals; Barbiturates; Central Nervous System Stimulants; Depressio

1963
A NEW CHEMICAL STRUCTURE WITH SPECIFIC DEPRESSANT EFFECTS ON THE AMYGDALA AND ON THE HYPER-IRRITABILITY OF THE 'SEPTAL RAT'.
    Nature, 1963, Oct-26, Volume: 200

    Topics: Amygdala; Cats; Cerebral Ventricles; Chlordiazepoxide; Chlorpromazine; Depression; Electric Stimulat

1963
THE HISTOMORPHOLOGY OF EXPERIMENTAL EXCITATION.
    Neurology, 1964, Volume: 14

    Topics: Acridines; Coloring Agents; Depression; Depressive Disorder; Hippocampus; Histology; Lysergic Acid D

1964
[CLINICAL EXPERIENCES WITH PENTOBARBITAL IN A PSYCHIATRIC CLINIC].
    Medizinische Klinik, 1964, Jul-03, Volume: 59

    Topics: Bipolar Disorder; Depression; Depressive Disorder, Major; Drug Therapy; Humans; Mental Disorders; Pa

1964
Sodium succinate in pentobarbital depression of the cerebral cortex and medulla oblongata.
    Anesthesiology, 1955, Volume: 16, Issue:2

    Topics: Barbiturates; Cerebral Cortex; Depression; Medulla Oblongata; Metabolism; Pentobarbital; Sodium; Suc

1955
Studies on the depression of brain oxidations; biopsy technique and analysis of variance in the selection of a pentobarbital concentration.
    The Journal of laboratory and clinical medicine, 1949, Volume: 34, Issue:6

    Topics: Analysis of Variance; Biopsy; Brain; Depression; Depressive Disorder; Neurochemistry; Pentobarbital

1949
Personality factors in human drug self-administration.
    NIDA research monograph, 1981, Volume: 37

    Topics: Adult; Depression; Female; Humans; Male; Middle Aged; MMPI; Pentobarbital; Personality; Self Adminis

1981
Potentiation of muscimol-induced long-term depression by benzodiazepines and prevention or reversal by pregnenolone sulfate.
    Pharmacological research, 1998, Volume: 38, Issue:6

    Topics: Amnesia; Animals; Barbiturates; Benzodiazepines; Cognition Disorders; Depression; Diazepam; Drug Syn

1998
Effect of leaf essential oil from Piper solmsianum C.DC. in mice behaviour.
    Anais da Academia Brasileira de Ciencias, 2001, Volume: 73, Issue:1

    Topics: Akathisia, Drug-Induced; Animals; Antifungal Agents; Behavior, Animal; Depression; Diazepam; Dioxola

2001
Drug therapy in alcoholism.
    Current psychiatric therapies, 1970, Volume: 10

    Topics: Adult; Alcoholic Intoxication; Alcoholism; Antidepressive Agents; Anxiety; Carbamates; Chlordiazepox

1970
[Paradoxical sleep in depressed patients. Effect of methaqualone and pentobarbital].
    Archivos de investigacion medica, 1971, Volume: 2, Issue:2

    Topics: Adult; Depression; Humans; Male; Methaqualone; Middle Aged; Pentobarbital; Sleep, REM

1971
[Paradoxical sleep in depressed patients. Effects of methaqualone and pentobarbital].
    Archivos de investigacion medica, 1971, Volume: 2, Issue:2

    Topics: Adult; Depression; Humans; Male; Methaqualone; Middle Aged; Pentobarbital; Sleep Initiation and Main

1971
Human sleep after leucotomy. A case study.
    Archives of general psychiatry, 1972, Volume: 26, Issue:5

    Topics: Amitriptyline; Chlorpromazine; Depression; Electroencephalography; Female; Frontal Lobe; Humans; Mid

1972
REM deprivation. II. The effects on depressed patients.
    Archives of general psychiatry, 1968, Volume: 18, Issue:3

    Topics: Amitriptyline; Catecholamines; Depression; Dreams; Electroencephalography; Eye Movements; Female; Hu

1968