cgp 12177 has been researched along with Depression in 4 studies
CGP 12177 : A benzimidazole that is benzimidazol-2-one substituted at position 4 by a 3-(tert-butylamino)-2-hydroxypropoxy group.
Depression: Depressive states usually of moderate intensity in contrast with MAJOR DEPRESSIVE DISORDER present in neurotic and psychotic disorders.
| Excerpt | Relevance | Reference |
|---|---|---|
| "beta-Adrenoceptor binding sites were measured by saturation binding of [3H]CGP 12177 in nine brain regions from 13 suicides, with a firm retrospective diagnosis of depression, who had been receiving antidepressant drugs, and 11 matched controls." | 3.68 | Brain beta-adrenoceptor binding sites in depressed suicide victims: effects of antidepressant treatment. ( Cheetham, SC; Crompton, MR; De Paermentier, F; Horton, RW; Katona, CL, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, HT | 1 |
| Whisler, LR | 1 |
| Huang, Y | 1 |
| Xiang, Y | 1 |
| O'Donnell, JM | 1 |
| Papp, M | 1 |
| Nalepa, I | 1 |
| Vetulani, J | 1 |
| Sastre, M | 1 |
| Guimón, J | 1 |
| García-Sevilla, JA | 1 |
| De Paermentier, F | 1 |
| Cheetham, SC | 1 |
| Crompton, MR | 1 |
| Katona, CL | 1 |
| Horton, RW | 1 |
4 other studies available for cgp 12177 and Depression
| Article | Year |
|---|---|
Postsynaptic alpha-2 adrenergic receptors are critical for the antidepressant-like effects of desipramine on behavior.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic beta-An | 2009 |
Reversal by imipramine of beta-adrenoceptor up-regulation induced in a chronic mild stress model of depression.
Topics: Adenylyl Cyclases; Adrenergic beta-Antagonists; Animals; Cerebral Cortex; Chronic Disease; Depressio | 1994 |
Relationships between beta- and alpha2-adrenoceptors and G coupling proteins in the human brain: effects of age and suicide.
Topics: Adolescent; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Ad | 2001 |
Brain beta-adrenoceptor binding sites in depressed suicide victims: effects of antidepressant treatment.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Antidepressive Agents; Brain Chemistry; Cerebr | 1991 |