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cgp 12177 and Depression

cgp 12177 has been researched along with Depression in 4 studies

CGP 12177 : A benzimidazole that is benzimidazol-2-one substituted at position 4 by a 3-(tert-butylamino)-2-hydroxypropoxy group.

Depression: Depressive states usually of moderate intensity in contrast with MAJOR DEPRESSIVE DISORDER present in neurotic and psychotic disorders.

Research Excerpts

ExcerptRelevanceReference
"beta-Adrenoceptor binding sites were measured by saturation binding of [3H]CGP 12177 in nine brain regions from 13 suicides, with a firm retrospective diagnosis of depression, who had been receiving antidepressant drugs, and 11 matched controls."3.68Brain beta-adrenoceptor binding sites in depressed suicide victims: effects of antidepressant treatment. ( Cheetham, SC; Crompton, MR; De Paermentier, F; Horton, RW; Katona, CL, 1991)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (50.00)18.2507
2000's2 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Zhang, HT1
Whisler, LR1
Huang, Y1
Xiang, Y1
O'Donnell, JM1
Papp, M1
Nalepa, I1
Vetulani, J1
Sastre, M1
Guimón, J1
García-Sevilla, JA1
De Paermentier, F1
Cheetham, SC1
Crompton, MR1
Katona, CL1
Horton, RW1

Other Studies

4 other studies available for cgp 12177 and Depression

ArticleYear
Postsynaptic alpha-2 adrenergic receptors are critical for the antidepressant-like effects of desipramine on behavior.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2009, Volume: 34, Issue:4

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic beta-An

2009
Reversal by imipramine of beta-adrenoceptor up-regulation induced in a chronic mild stress model of depression.
    European journal of pharmacology, 1994, Aug-11, Volume: 261, Issue:1-2

    Topics: Adenylyl Cyclases; Adrenergic beta-Antagonists; Animals; Cerebral Cortex; Chronic Disease; Depressio

1994
Relationships between beta- and alpha2-adrenoceptors and G coupling proteins in the human brain: effects of age and suicide.
    Brain research, 2001, Apr-20, Volume: 898, Issue:2

    Topics: Adolescent; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Ad

2001
Brain beta-adrenoceptor binding sites in depressed suicide victims: effects of antidepressant treatment.
    Psychopharmacology, 1991, Volume: 105, Issue:2

    Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Antidepressive Agents; Brain Chemistry; Cerebr

1991