4-phenylbutyric acid has been researched along with Depression in 2 studies
4-phenylbutyric acid: RN refers to the parent cpd
4-phenylbutyric acid : A monocarboxylic acid the structure of which is that of butyric acid substituted with a phenyl group at C-4. It is a histone deacetylase inhibitor that displays anticancer activity. It inhibits cell proliferation, invasion and migration and induces apoptosis in glioma cells. It also inhibits protein isoprenylation, depletes plasma glutamine, increases production of foetal haemoglobin through transcriptional activation of the gamma-globin gene and affects hPPARgamma activation.
Depression: Depressive states usually of moderate intensity in contrast with MAJOR DEPRESSIVE DISORDER present in neurotic and psychotic disorders.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jangra, A | 2 |
| Sriram, CS | 2 |
| Dwivedi, S | 1 |
| Gurjar, SS | 1 |
| Hussain, MI | 1 |
| Borah, P | 1 |
| Lahkar, M | 2 |
2 other studies available for 4-phenylbutyric acid and Depression
| Article | Year |
|---|---|
Sodium Phenylbutyrate and Edaravone Abrogate Chronic Restraint Stress-Induced Behavioral Deficits: Implication of Oxido-Nitrosative, Endoplasmic Reticulum Stress Cascade, and Neuroinflammation.
Topics: Animals; Antipyrine; Chronic Disease; Depression; Dose-Response Relationship, Drug; Edaravone; Endop | 2017 |
Lipopolysaccharide-Induced Behavioral Alterations Are Alleviated by Sodium Phenylbutyrate via Attenuation of Oxidative Stress and Neuroinflammatory Cascade.
Topics: Animals; Anxiety; Behavioral Symptoms; Depression; Encephalitis; Endoplasmic Reticulum Chaperone BiP | 2016 |