Page last updated: 2024-10-26

doxepin and Depression

doxepin has been researched along with Depression in 90 studies

Doxepin: A dibenzoxepin tricyclic compound. It displays a range of pharmacological actions including maintaining adrenergic innervation. Its mechanism of action is not fully understood, but it appears to block reuptake of monoaminergic neurotransmitters into presynaptic terminals. It also possesses anticholinergic activity and modulates antagonism of histamine H(1)- and H(2)-receptors.
doxepin : A dibenzooxepine that is 6,11-dihydrodibenzo[b,e]oxepine substituted by a 3-(dimethylamino)propylidene group at position 11. It is used as an antidepressant drug.

Depression: Depressive states usually of moderate intensity in contrast with MAJOR DEPRESSIVE DISORDER present in neurotic and psychotic disorders.

Research Excerpts

ExcerptRelevanceReference
"Thirty patients with chronic low back or cervical pain combined with clinical depression were studied in a six-week, randomized, double-blind comparison of doxepin and placebo."9.05Doxepin effects on chronic pain, depression and plasma opioids. ( Cork, RC; Crago, BR; Davis, TP; Hameroff, SR; Neuman, C; Scherer, K; Womble, JR, 1982)
"Twenty-one patients with endoscopically proven active duodenal ulcers were studied in a double-blind randomized trial comparing doxepin hydrochloride (50 mg during the first week, and 100 mg thereafter, at bedtime) and cimetidine (1,200 mg/day in four divided doses)."9.05Doxepin and cimetidine in the treatment of duodenal ulcer: a double-blind comparative study. ( Shah, BK; Shrivastava, RK; Siegal, H, 1985)
"Maprotiline (Ludiomil) and doxepin were compared in the treatment of depression in a double-blind multicentre trial."9.04Maprotiline and doxepin in the treatment of depression. A double-glind multicentre comparison. ( Heikkilä, L; Kontiainen, H; Malinen, L; Meriläinen, V; Naarala, M; Väisänen, E, 1978)
"Thirty patients with chronic low back or cervical pain combined with clinical depression were studied in a six-week, randomized, double-blind comparison of doxepin and placebo."5.05Doxepin effects on chronic pain, depression and plasma opioids. ( Cork, RC; Crago, BR; Davis, TP; Hameroff, SR; Neuman, C; Scherer, K; Womble, JR, 1982)
"Twenty-one patients with endoscopically proven active duodenal ulcers were studied in a double-blind randomized trial comparing doxepin hydrochloride (50 mg during the first week, and 100 mg thereafter, at bedtime) and cimetidine (1,200 mg/day in four divided doses)."5.05Doxepin and cimetidine in the treatment of duodenal ulcer: a double-blind comparative study. ( Shah, BK; Shrivastava, RK; Siegal, H, 1985)
"Maprotiline (Ludiomil) and doxepin were compared in the treatment of depression in a double-blind multicentre trial."5.04Maprotiline and doxepin in the treatment of depression. A double-glind multicentre comparison. ( Heikkilä, L; Kontiainen, H; Malinen, L; Meriläinen, V; Naarala, M; Väisänen, E, 1978)
"Trebenzomine, a new psychotropic drug, was compared with doxepin in the treatment of anxiety and depression."5.04Controlled comparison of trebenzomine with doxepin as an antidepressant-anxiolytic. ( Borgen, LA; Goodman, LI; Muniz, C; Pena-Ramos, A, 1979)
" Retrospectively, both subjects suffered from psychiatric disorders and in case 2, the subject was treated for depression with doxepin."3.81Sleep self-intoxication and sleep driving as rare zolpidem-induced complex behaviour. ( Paulke, A; Toennes, SW; Wunder, C, 2015)
"3."3.74A review of controlled studies with nomifensine, performed outside the UK. ( Habermann, W, 1977)
" In this study, we examined, using positron emission tomography (PET) and [(11)C]-doxepin, whether the histaminergic neuron system is involved in human depression."3.72Decreased histamine H1 receptor binding in the brain of depressed patients. ( Fukudo, S; Funaki, Y; Hongo, M; Itoh, M; Iwata, R; Kano, M; Kato, M; Mochizuki, H; Tamura, D; Tashiro, A; Tashiro, M; Utsumi, A; Yanai, K, 2004)
"Doxepin is a tricyclic antidepressant that is widely prescribed for the treatment of mild depression."3.70Detection of doxepin and its major metabolite desmethyldoxepin in hair following drug therapy. ( Moore, CM; Negrusz, A; Perry, JL, 1998)
"A group of moderately to severely depressed individuals with moderate anxiety were studied to determine the frequency and nature of pain complaints and their response to doxepin."3.66The effectiveness of tricyclic antidepressants in the treatment of coexisting pain and depression. ( Bloom, VL; Friedel, RO; Ward, NG, 1979)
"Diazepam treated patients improved significantly more early in the trial, according to a few measures."2.64Doxepin or diazepam for anxious and anxious-depressed outpatients? ( Fisher, S; Gambill, JD; Gardos, G; Haskell, DS; McNair, DM, 1978)
"Treatment with doxepin is a contraindication to driving during the first two weeks or up to the time when amelioration of symptoms is recorded."2.64Psychomotor skills in depressed out-patients treated with L-tryptophan, doxepin, or chlorimipramine. ( Linnoila, M; Mattila, MJ; Seppälä, T, 1978)
"Such approach to treatment of insomnia in depressed patients protects them against dependence on hypnotic drugs."2.47[The effects of antidepressants on sleep in depressed patients with particular reference to trazodone in comparison to agomelatine, amitriptyline, doxepin, mianserine and mirtazapine]. ( Wichniak, A; Wierzbicka, A, 2011)
"Menopause is a period of higher depressive vulnerability."1.43Ovariectomy changes the response to antidepressant drugs in tail suspension test in mice. ( Huang, S; Liu, C; Liu, X; Ye, Y, 2016)
" As a consequence, if a combination of valproic acid with doxepin or venlafaxine is administered, cautious dosing is advisable and TDM should be performed."1.40Interaction of valproic acid and the antidepressant drugs doxepin and venlafaxine: analysis of therapeutic drug monitoring data under naturalistic conditions. ( Deckert, J; Hempel, S; Pfuhlmann, B; Proft, F; Reif, A; Riederer, P; Unterecker, S, 2014)
" The dialysis experiments show that modification of the usual dosage regimen is not necessary during hemodialysis or on dialysis days."1.27Hemodialysis of doxepin and desmethyldoxepin in uremic patients. ( Faulkner, RD; Lee, CS; Senekjian, HO, 1984)
"Doxepin was used as the anti-depressant in a double blind procedure."1.27Emotional problems during weight reduction: advantages of a combined behavior therapy and antidepressive drug therapy for obesity. ( Cayiroglu, S; Nutzinger, DO; Sachs, G; Zapotoczky, HG, 1985)
"), and repeated after changing the dosage schedule to a single daily bedtime (h."1.26Dosage schedule and plasma levels of doxepin and desmethyldoxepin. ( Biggs, JT; Meyer, DA; Preskorn, SH; Rosen, SH; Ziegler, VE, 1978)

Research

Studies (90)

TimeframeStudies, this research(%)All Research%
pre-199073 (81.11)18.7374
1990's8 (8.89)18.2507
2000's3 (3.33)29.6817
2010's6 (6.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sun, Y1
Liang, Y1
Jiao, Y1
Lin, J1
Qu, H1
Xu, J1
Zhao, C1
Unterecker, S1
Reif, A1
Hempel, S1
Proft, F1
Riederer, P1
Deckert, J1
Pfuhlmann, B1
Paulke, A1
Wunder, C1
Toennes, SW1
Ye, Y1
Liu, C1
Liu, X1
Huang, S1
Wichniak, A1
Wierzbicka, A1
Clark, MS1
Smith, PO1
Jamieson, B1
Kano, M1
Fukudo, S1
Tashiro, A1
Utsumi, A1
Tamura, D1
Itoh, M1
Iwata, R1
Tashiro, M1
Mochizuki, H1
Funaki, Y1
Kato, M1
Hongo, M1
Yanai, K1
Meagher, LJ1
McKay, D1
Herkes, GK1
Needham, M1
Koval'chuk, VV1
Hameroff, SR1
Cork, RC1
Scherer, K1
Crago, BR1
Neuman, C1
Womble, JR1
Davis, TP1
Abbott, R1
Ojemann, LM1
Friel, PN1
Trejo, WJ1
Dudley, DL1
Faulkner, RD1
Senekjian, HO1
Lee, CS1
Pies, RW1
Hertrich, O1
Amsterdam, J1
Brunswick, D1
Mendels, J2
Borg, V1
Murphy, JE1
Ankier, SI1
Marshall, JB1
Forker, AD1
Aronoff, GM1
Evans, WO1
Ward, NG2
Bloom, VL2
Wilson, L1
Raskind, M1
Raisys, VA1
Lindsay, PG1
Wyckoff, M1
Annitto, W1
Friedel, RO2
Klein, DF1
Ulmer, A1
Negrusz, A1
Moore, CM1
Perry, JL1
Ye, F1
Li, X1
Lu, Q1
de Sousa, MP1
Lopes, JS1
Figueira, L1
Cardoso, JN1
von Lieven, T1
Dietz, V1
Schulte, PW1
Woggon, B1
Angst, J1
Elwan, O1
Taher, Y1
Allam, M1
Hassan, MA1
Hollister, LE2
Pinder, RM1
Brogden, RN1
Speight, TM1
Avery, GS1
Habermann, W1
Amin, MM1
Ban, TA1
Lehmann, HE1
Marcotte, E1
Haskell, DS1
Gambill, JD1
Gardos, G1
McNair, DM2
Fisher, S1
Väisänen, E1
Naarala, M1
Kontiainen, H1
Meriläinen, V1
Heikkilä, L1
Malinen, L1
Linnoila, M3
Dorrity, F1
Jobson, K2
Pena-Ramos, A1
Muniz, C1
Goodman, LI1
Borgen, LA1
Barranco, SF1
Thrash, ML1
Hackett, E1
Frey, J1
Ward, J1
Norris, E1
Lieb, J1
Lieberman, PB1
Simmons, EC1
Loeser, JD1
Poe, TE1
Edwards, JL1
Taylor, RB1
Risch, SC1
Huey, LY1
Janowsky, DS1
Burnett, G1
Green, DO1
Seppälä, T1
Mattila, MJ1
Biggs, JT1
Preskorn, SH1
Ziegler, VE1
Rosen, SH1
Meyer, DA1
Roth, N1
Radmayr, E2
Lippmann, S1
Moskovitz, R1
O'Tuama, L1
Zink, CD1
Ratel, M1
Boucharlat, J1
Maitre, A1
Wolf, R1
Ledru, J1
Planche, R1
Gathier, MC1
Lambert, J1
Vanggaard, T1
Smith, JA1
Renshaw, DC1
Woody, GE1
O'Brien, CP1
Rickels, K1
Ayd, FJ1
Schless, A1
Langee, HR1
Conlon, M1
Lechin, F1
van der Dijs, B1
Lechin, A1
Lechin, M1
Coll-García, E1
Jara, H1
Cabrera, A1
Jiménez, V1
Gómez, F1
Tovar, D1
Rosenberg, PB1
Pearlman, CA1
Tversky, J1
Reade, PC1
Gerschman, JA1
Holwill, BJ1
Wright, J1
Orzack, MH1
Friedman, LM1
Marby, DW1
Waring, EM1
Chamberlaine, CH1
McCrank, EW1
Stalker, CA1
Carver, C1
Fry, R1
Barnes, S1
Harris, BA1
Sherertz, EF1
Flowers, FP1
Cunha, UV1
Mahapatra, RK1
Paul, SK1
Mahapatra, D1
Winter, S1
Shrivastava, RK1
Shah, BK1
Siegal, H1
Aaltonen, L1
Syvälahti, E1
Iisalo, E1
Peltomäki, T1
Nutzinger, DO1
Cayiroglu, S1
Sachs, G1
Zapotoczky, HG1
Ehrensing, RH1
Grof, P1
Saxena, B1
Cantor, R1
Daigle, L1
Hetherington, D1
Haines, T1
Pigott, PV1
Jeste, DV1
Vahia, NS1
Ravindranath, S1
Goldberg, HL1
Finnerty, RJ1
Cole, JO1
Náhunek, K1
Kamenická, V1
Cesková, E1
Rodová, A1
Svestka, J1
Misurec, J1
d'Elia, G1
von Knorring, L1
Marcusson, J1
Mattsson, B1
Perris, C1
Persson, G1
Downing, RW1
Murphy, HB1
Ciureza, T1
Tudorache, D1
Ionescu, R2
Niţurad, A1
Nica, S1
Oproiu, L1
Popovici, I1
Roman, I1
Curelaru, S1
Lankosz, J1
Weselucha, P1

Reviews

8 reviews available for doxepin and Depression

ArticleYear
[The effects of antidepressants on sleep in depressed patients with particular reference to trazodone in comparison to agomelatine, amitriptyline, doxepin, mianserine and mirtazapine].
    Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2011, Volume: 31, Issue:181

    Topics: Amitriptyline; Antidepressive Agents; Depression; Doxepin; Humans; Mianserin; Mirtazapine; Sleep; Sl

2011
The clinical application of tricyclic antidepressant pharmacokinetics and plasma levels.
    The American journal of psychiatry, 1980, Volume: 137, Issue:6

    Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Depression; Desipramine; Doxepin; Heart; Humans; Im

1980
Cardiovascular effects of tricyclic antidepressant drugs: therapeutic usage, overdose, and management of complications.
    American heart journal, 1982, Volume: 103, Issue:3

    Topics: Adult; Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Cardiovascular S

1982
Doxepin as an adjunct in the treatment of chronic pain.
    The Journal of clinical psychiatry, 1982, Volume: 43, Issue:8 Pt 2

    Topics: Chronic Disease; Clinical Trials as Topic; Depression; Depressive Disorder; Doxepin; Humans; Hydroxy

1982
Tricyclic antidepressants (first of two parts).
    The New England journal of medicine, 1978, Nov-16, Volume: 299, Issue:20

    Topics: Aged; Amines; Amitriptyline; Antidepressive Agents, Tricyclic; Chemical Phenomena; Chemistry; Child;

1978
Doxepin up-to-date: a review of its pharmacological properties and therapeutic efficacy with particular reference to depression.
    Drugs, 1977, Volume: 13, Issue:3

    Topics: Alcoholism; Amitriptyline; Animals; Anxiety; Cardiovascular Diseases; Depression; Doxepin; Drug Inte

1977
A review of controlled studies with nomifensine, performed outside the UK.
    British journal of clinical pharmacology, 1977, Volume: 4Suppl 2

    Topics: Adult; Aged; Amitriptyline; Clinical Trials as Topic; Depression; Double-Blind Method; Doxepin; Drug

1977
Self-evaluations of antidepressants.
    Psychopharmacologia, 1974, Volume: 37, Issue:4

    Topics: Amitriptyline; Antidepressive Agents; Chlordiazepoxide; Clinical Trials as Topic; Depression; Desipr

1974

Trials

32 trials available for doxepin and Depression

ArticleYear
[Pharmacologic correction of psycho-emotive disorders in the rehabilitation of patients after removal of brain tumors].
    Voprosy onkologii, 2007, Volume: 53, Issue:6

    Topics: Adult; Alprazolam; Amitriptyline; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Brain Neoplas

2007
Doxepin effects on chronic pain, depression and plasma opioids.
    The Journal of clinical psychiatry, 1982, Volume: 43, Issue:8 Pt 2

    Topics: Adult; Aged; beta-Endorphin; Chronic Disease; Depression; Double-Blind Method; Doxepin; Endorphins;

1982
[Clinical trial of Tegretol and Anafranil/Sinequan in alcohol abstinence symptoms].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1980, Feb-20, Volume: 100, Issue:5

    Topics: Alcoholism; Carbamazepine; Clinical Trials as Topic; Clomipramine; Depression; Double-Blind Method;

1980
An evaluation of trazodone in the treatment of depression.
    Neuropharmacology, 1980, Volume: 19, Issue:12

    Topics: Adolescent; Adult; Aged; Amitriptyline; Clinical Trials as Topic; Depression; Double-Blind Method; D

1980
Doxepin as an adjunct in the treatment of chronic pain.
    The Journal of clinical psychiatry, 1982, Volume: 43, Issue:8 Pt 2

    Topics: Chronic Disease; Clinical Trials as Topic; Depression; Depressive Disorder; Doxepin; Humans; Hydroxy

1982
Doxepin plasma levels and therapeutic response in depression: preliminary findings.
    Journal of clinical psychopharmacology, 1982, Volume: 2, Issue:2

    Topics: Chromatography, Gas; Depression; Dose-Response Relationship, Drug; Doxepin; Female; Gas Chromatograp

1982
[Comparative study of three psychotropics for treatment of depressions].
    International pharmacopsychiatry, 1976, Volume: 11, Issue:1

    Topics: Adult; Clinical Trials as Topic; Clomipramine; Depression; Dibenzazepines; Doxepin; Female; Humans;

1976
[Activity profile of carpipramine. Results of an open trial and a double-blind trial versus doxepin].
    Arzneimittel-Forschung, 1976, Volume: 26, Issue:12

    Topics: Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Benzodiazepines; Clinic

1976
A comparative study of antidepressants in the treatment of depressive states.
    The Journal of international medical research, 1976, Volume: 4, Issue:3

    Topics: Adult; Aged; Amitriptyline; Antidepressive Agents; Depression; Dibenzazepines; Dibenzocycloheptenes;

1976
A review of controlled studies with nomifensine, performed outside the UK.
    British journal of clinical pharmacology, 1977, Volume: 4Suppl 2

    Topics: Adult; Aged; Amitriptyline; Clinical Trials as Topic; Depression; Double-Blind Method; Doxepin; Drug

1977
Doxepin and imipramine in the treatment of depression: a double-blind crossover clinical study with EKG recordings.
    Psychopharmacology bulletin, 1978, Volume: 14, Issue:1

    Topics: Adjustment Disorders; Adult; Bipolar Disorder; Clinical Trials as Topic; Depression; Double-Blind Me

1978
Doxepin or diazepam for anxious and anxious-depressed outpatients?
    The Journal of clinical psychiatry, 1978, Volume: 39, Issue:2

    Topics: Adolescent; Adult; Aged; Ambulatory Care; Anxiety; Body Weight; Clinical Trials as Topic; Depression

1978
Maprotiline and doxepin in the treatment of depression. A double-glind multicentre comparison.
    Acta psychiatrica Scandinavica, 1978, Volume: 57, Issue:3

    Topics: Adjustment Disorders; Adult; Affective Disorders, Psychotic; Anthracenes; Clinical Trials as Topic;

1978
Plasma and erythrocyte levels of tricyclic antidepressants in depressed patients.
    The American journal of psychiatry, 1978, Volume: 135, Issue:5

    Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Biopharmaceutics; Clinical Trials as Topic;

1978
Controlled comparison of trebenzomine with doxepin as an antidepressant-anxiolytic.
    The Journal of clinical psychiatry, 1979, Volume: 40, Issue:2

    Topics: Adult; Anxiety; Benzopyrans; Chromans; Clinical Trials as Topic; Depression; Double-Blind Method; Do

1979
Early onset of response to doxepin treatment.
    The Journal of clinical psychiatry, 1979, Volume: 40, Issue:6

    Topics: Adjustment Disorders; Adolescent; Adult; Aged; Clinical Trials as Topic; Depression; Double-Blind Me

1979
Psychomotor skills in depressed out-patients treated with L-tryptophan, doxepin, or chlorimipramine.
    Annals of clinical research, 1978, Volume: 10, Issue:4

    Topics: Adult; Attention; Clomipramine; Depression; Dibenzazepines; Doxepin; Female; Humans; Male; Middle Ag

1978
A comparison between dothiepin and doxepin in the treatment of depression.
    The Practitioner, 1976, Volume: 216, Issue:1295

    Topics: Clinical Trials as Topic; Depression; Dibenzothiepins; Dothiepin; Doxepin; Female; Humans; Male

1976
A clinical study of insomnia.
    American family physician, 1975, Volume: 11, Issue:3

    Topics: Adult; Aged; Anxiety Disorders; Clinical Trials as Topic; Depression; Doxepin; Drug Therapy, Combina

1975
Depression and anxiety in heroin addicts: a placebo-controlled study of doxepin in combination with methadone.
    The American journal of psychiatry, 1975, Volume: 132, Issue:4

    Topics: Administration, Oral; Adult; Alcoholic Intoxication; Amphetamine; Anxiety; Barbiturates; Capsules; C

1975
A controlled comparison of doxepin h.s. and doxepin q.i.d.
    Journal of clinical pharmacology, 1975, Volume: 15, Issue:7

    Topics: Adult; Anxiety; Depression; Doxepin; Female; Humans; Male; Middle Aged; Placebos; Psychiatric Status

1975
Weight changes on fluoxetine as a function of baseline weight in depressed outpatients.
    Psychopharmacology bulletin, 1990, Volume: 26, Issue:3

    Topics: Adult; Aged; Body Weight; Depression; Double-Blind Method; Doxepin; Female; Fluoxetine; Humans; Male

1990
Dysthymia: a randomized study of cognitive marital therapy and antidepressants.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1988, Volume: 33, Issue:2

    Topics: Clinical Trials as Topic; Combined Modality Therapy; Depression; Double-Blind Method; Doxepin; Femal

1988
Doxepin and cimetidine in the treatment of duodenal ulcer: a double-blind comparative study.
    Clinical therapeutics, 1985, Volume: 7, Issue:2

    Topics: Adult; Aged; Anxiety; Cimetidine; Clinical Trials as Topic; Depression; Double-Blind Method; Doxepin

1985
Self-evaluations of antidepressants.
    Psychopharmacologia, 1974, Volume: 37, Issue:4

    Topics: Amitriptyline; Antidepressive Agents; Chlordiazepoxide; Clinical Trials as Topic; Depression; Desipr

1974
Doxepin versus amitriptyline in depression: a sequential double-blind study.
    Current therapeutic research, clinical and experimental, 1974, Volume: 16, Issue:5

    Topics: Amitriptyline; Anxiety; Depression; Doxepin; Female; Humans; Hypochondriasis; Intellectual Disabilit

1974
A review of clinical studies with combinations of fluphenazine and nortriptyline.
    Current medical research and opinion, 1972, Volume: 1, Issue:1

    Topics: Amitriptyline; Anxiety; Central Nervous System; Clinical Trials as Topic; Depression; Diazepam; Doxe

1972
A comparative study of doxepin and placebo in depression.
    Indian journal of medical sciences, 1973, Volume: 27, Issue:10

    Topics: Adult; Clinical Trials as Topic; Depression; Doxepin; Female; Humans; Male; Middle Aged; Placebos; P

1973
Doxepin hydrochloride.
    Annals of internal medicine, 1974, Volume: 81, Issue:3

    Topics: Alcoholism; Amitriptyline; Anxiety; Clinical Trials as Topic; Depression; Doxepin; Drug Evaluation;

1974
Doxepin: is a single daily dose enough?
    The American journal of psychiatry, 1974, Volume: 131, Issue:9

    Topics: Administration, Oral; Adult; Anxiety; Clinical Trials as Topic; Depression; Doxepin; Drug Evaluation

1974
Clinical experience with doxepin.
    Activitas nervosa superior, 1974, Volume: 16, Issue:3

    Topics: Adolescent; Adult; Aged; Chemical and Drug Induced Liver Injury; Clinical Trials as Topic; Depressio

1974
A double blind comparison between doxepin and diazepam in the treatment of states of anxiety.
    Acta psychiatrica Scandinavica. Supplementum, 1974, Volume: 255

    Topics: Adolescent; Adult; Aged; Anxiety; Body Weight; Clinical Trials as Topic; Depression; Diazepam; Doxep

1974

Other Studies

53 other studies available for doxepin and Depression

ArticleYear
Comparative efficacy and acceptability of antidepressant treatment in poststroke depression: a multiple-treatments meta-analysis.
    BMJ open, 2017, Aug-03, Volume: 7, Issue:8

    Topics: Aged; Antidepressive Agents; Antidepressive Agents, Second-Generation; Citalopram; Depression; Depre

2017
Interaction of valproic acid and the antidepressant drugs doxepin and venlafaxine: analysis of therapeutic drug monitoring data under naturalistic conditions.
    International clinical psychopharmacology, 2014, Volume: 29, Issue:4

    Topics: Adult; Aged; Antidepressive Agents; Biotransformation; Cyclohexanols; Depression; Dose-Response Rela

2014
Sleep self-intoxication and sleep driving as rare zolpidem-induced complex behaviour.
    International journal of legal medicine, 2015, Volume: 129, Issue:1

    Topics: Adult; Amnesia; Antidepressive Agents, Tricyclic; Automobile Driving; Depression; Doxepin; Drug Over

2015
Ovariectomy changes the response to antidepressant drugs in tail suspension test in mice.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2016, Volume: 32, Issue:12

    Topics: Animals; Antidepressive Agents; Behavior, Animal; Depression; Disease Models, Animal; Doxepin; Estro

2016
FPIN's clinical inquiries: Antidepressants for the treatment of insomnia in patients with depression.
    American family physician, 2011, Nov-01, Volume: 84, Issue:9

    Topics: Amitriptyline; Antidepressive Agents; Antidepressive Agents, Tricyclic; Depression; Dose-Response Re

2011
Decreased histamine H1 receptor binding in the brain of depressed patients.
    The European journal of neuroscience, 2004, Volume: 20, Issue:3

    Topics: Adult; Brain; Brain Mapping; Carbon Radioisotopes; Case-Control Studies; Depression; Doxepin; Humans

2004
Parkinsonism-hyperpyrexia syndrome: the role of electroconvulsive therapy.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2006, Volume: 13, Issue:8

    Topics: Acetaminophen; Acyclovir; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Anxiety Agents; Anti-Ba

2006
Hyponatremia due to antidepressant medications.
    Annals of emergency medicine, 1983, Volume: 12, Issue:11

    Topics: Amitriptyline; Amoxapine; Antidepressive Agents, Tricyclic; Depression; Doxepin; Emergencies; Female

1983
Effect of doxepin on seizure frequency in depressed epileptic patients.
    Neurology, 1983, Volume: 33, Issue:5

    Topics: Adolescent; Adult; Depression; Doxepin; Epilepsy; Female; Humans; Male; Middle Aged

1983
Hemodialysis of doxepin and desmethyldoxepin in uremic patients.
    Artificial organs, 1984, Volume: 8, Issue:2

    Topics: Adult; Aged; Depression; Doxepin; Half-Life; Humans; Middle Aged; Renal Dialysis; Uremia

1984
Another case of doxepin for irritable bowel syndrome.
    The American journal of psychiatry, 1983, Volume: 140, Issue:3

    Topics: Adult; Colonic Diseases, Functional; Depression; Doxepin; Humans; Hypochondriasis; Male

1983
[Ataractic treatment in psychiatry and general medicine. Review of drugs. 5].
    Fortschritte der Medizin, 1983, Jul-14, Volume: 101, Issue:26

    Topics: Acridines; Anxiety Disorders; Dementia; Depression; Doxepin; Humans; Mental Disorders; Mood Disorder

1983
The depression-pain syndrome and its response to antidepressants.
    Psychosomatics, 1981, Volume: 22, Issue:7

    Topics: Adolescent; Adult; Aged; Amitriptyline; Antidepressive Agents; Depression; Desipramine; Doxepin; Fem

1981
Excessive caution in psychotropic dosage.
    Psychosomatics, 1980, Volume: 21, Issue:5

    Topics: Aged; Depression; Diagnosis, Differential; Doxepin; Female; Geriatric Psychiatry; Humans

1980
The pharmacotherapy of depression in the elderly: pharmacokinetic considerations.
    Proceedings of the annual meeting of the American Psychopathological Association, 1980, Volume: 69

    Topics: Absorption; Adolescent; Aged; Antidepressive Agents, Tricyclic; Biopharmaceutics; Depression; Doxepi

1980
Clinical and biological aspects of depression in the elderly.
    Proceedings of the annual meeting of the American Psychopathological Association, 1980, Volume: 69

    Topics: Aged; Dementia; Depression; Doxepin; Humans; Imipramine; Methylphenidate; Middle Aged; Trazodone

1980
[Cerebral seizures under doxepin during a substitution with dihydrocodeine].
    Deutsche medizinische Wochenschrift (1946), 1994, Sep-16, Volume: 119, Issue:37

    Topics: Brain Diseases; Codeine; Depression; Doxepin; Humans; Seizures; Substance Withdrawal Syndrome

1994
Detection of doxepin and its major metabolite desmethyldoxepin in hair following drug therapy.
    Journal of analytical toxicology, 1998, Volume: 22, Issue:6

    Topics: Adult; Antidepressive Agents, Tricyclic; Depression; Doxepin; Female; Gas Chromatography-Mass Spectr

1998
[Symptoms of depressive state in otolaryngology].
    Zhonghua er bi yan hou ke za zhi, 1997, Volume: 32, Issue:2

    Topics: Adolescent; Adult; Antidepressive Agents, Tricyclic; Depression; Diagnosis, Differential; Doxepin; E

1997
[Drug-induced chronic hallucinosis. A case of chronic hallucinosis in an elderly patient following long-term use of psycholeptic drugs].
    Der Nervenarzt, 1976, Volume: 47, Issue:3

    Topics: Aged; Amitriptyline; Antipsychotic Agents; Depression; Doxepin; Female; Hallucinations; Humans; Hypo

1976
Advisability of combined treatment.
    The American journal of psychiatry, 1979, Volume: 136, Issue:5

    Topics: Depression; Doxepin; Drug Therapy, Combination; Humans; Tranylcypromine

1979
Family practice management of depression: how to select tricyclic antidepressants.
    Southern medical journal, 1979, Volume: 72, Issue:6

    Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Depression; Doxepin; Family Practice; Humans; Imipr

1979
Effects of doxepin on perception of laboratory-induced pain in man.
    Pain, 1979, Volume: 6, Issue:2

    Topics: Depression; Doxepin; Humans; Pain Management; Pain, Intractable; Research Design

1979
Hypertensive crisis possibly due to drug interaction.
    Postgraduate medicine, 1979, Volume: 66, Issue:5

    Topics: Blood Pressure; Chlorpromazine; Depression; Doxepin; Drug Interactions; Guanethidine; Humans; Hypert

1979
The effectiveness of tricyclic antidepressants in the treatment of coexisting pain and depression.
    Pain, 1979, Volume: 7, Issue:3

    Topics: Chronic Disease; Depression; Doxepin; Headache; Humans; Pain; Placebos

1979
Plasma levels of tricyclic antidepressants and clinical efficacy: review of the literature -- part II.
    The Journal of clinical psychiatry, 1979, Volume: 40, Issue:2

    Topics: Antidepressive Agents, Tricyclic; Biotransformation; Clomipramine; Depression; Desipramine; Dibenzoc

1979
Weight loss and a concomitant change in plasma tricyclic levels.
    The American journal of psychiatry, 1978, Volume: 135, Issue:2

    Topics: Adult; Body Weight; Depression; Doxepin; Female; Humans; Recurrence; Smoking

1978
Clinical importance of doxepin antidepressant plasma levels.
    The Journal of clinical psychiatry, 1978, Volume: 39, Issue:5

    Topics: Depression; Dose-Response Relationship, Drug; Doxepin; Female; Humans; Middle Aged

1978
Dosage schedule and plasma levels of doxepin and desmethyldoxepin.
    The Journal of clinical psychiatry, 1978, Volume: 39, Issue:10

    Topics: Adult; Aged; Depression; Doxepin; Drug Administration Schedule; Drug Evaluation; Female; Humans; Mid

1978
Fear of death in the aging.
    American journal of psychotherapy, 1978, Volume: 32, Issue:4

    Topics: Aged; Aging; Anxiety; Attitude to Death; Culture; Depression; Doxepin; Fear; Female; Humans; Male; M

1978
[Long-term therapy using Sinquan. Studies on tolerance, under systematic control of laboratory values].
    Die Medizinische Welt, 1976, Feb-27, Volume: 27, Issue:9

    Topics: Aged; Depression; Doxepin; Female; Humans; Long-Term Care; Male; Middle Aged

1976
Tricyclic-induced myoclonus.
    The American journal of psychiatry, 1977, Volume: 134, Issue:1

    Topics: Adult; Amitriptyline; Depression; Doxepin; Humans; Male; Methysergide; Myoclonus; Physostigmine

1977
[Experience with Sinquan in a single bedtime dose].
    Die Medizinische Welt, 1977, Jun-24, Volume: 28, Issue:25

    Topics: Adult; Depression; Doxepin; Drug Evaluation; Female; Humans; Male; Middle Aged; Psychotic Disorders;

1977
[Vegetative exhaustion depression. Experience of a locum-tenens].
    ZFA. Zeitschrift fur Allgemeinmedizin, 1977, Oct-20, Volume: 53, Issue:29

    Topics: Adult; Depression; Doxepin; Female; Humans; Male; Psychophysiologic Disorders; Tranquilizing Agents

1977
[Acute catatonia with favorable course. Apropos of 2 cases].
    Annales medico-psychologiques, 1976, Volume: 1, Issue:2

    Topics: Acute Disease; Adult; Ambulatory Care; Antidepressive Agents; Catatonia; Delusions; Depression; Doxe

1976
[Description of a simple graphic model permitting the comparison of the course of depressive states].
    Annales medico-psychologiques, 1976, Volume: 2, Issue:4

    Topics: Adjustment Disorders; Adult; Antidepressive Agents; Anxiety; Clomipramine; Depression; Doxepin; Fema

1976
Atypical endogenous depression. Diagnostic criteria.
    Acta psychiatrica Scandinavica. Supplementum, 1976, Volume: 267

    Topics: Adult; Amitriptyline; Depression; Doxepin; Family; Female; Humans; Imipramine; Interpersonal Relatio

1976
Maintenance doxepin (sinequan) therapy for depressive illness.
    Diseases of the nervous system, 1975, Volume: 36, Issue:3

    Topics: Adult; Aged; Bipolar Disorder; Chemical and Drug Induced Liver Injury; Chronic Disease; Depression;

1975
[Drug information. Doxepin (Sinquan)].
    Ugeskrift for laeger, 1975, Jul-21, Volume: 137, Issue:30

    Topics: Depression; Doxepin; Humans

1975
Predictors of response to antidepressant medications.
    American journal of mental retardation : AJMR, 1992, Volume: 97, Issue:1

    Topics: Aggression; Amitriptyline; Antidepressive Agents; Depression; Doxepin; Follow-Up Studies; Humans; In

1992
Doxepin therapy for postprandial symptomatic hypoglycaemic patients: neurochemical, hormonal and metabolic disturbances.
    Clinical science (London, England : 1979), 1991, Volume: 80, Issue:4

    Topics: Adult; Autonomic Nervous System; Depression; Dopamine; Doxepin; Epinephrine; Female; Glucose Toleran

1991
NMS-Like syndrome with a lithium/doxepin combination.
    Journal of clinical psychopharmacology, 1991, Volume: 11, Issue:1

    Topics: Depression; Doxepin; Drug Therapy, Combination; Humans; Lithium; Male; Middle Aged; Neuroleptic Mali

1991
Role of depressive illness in the outcome of treatment of temporomandibular joint pain-dysfunction syndrome.
    Oral surgery, oral medicine, and oral pathology, 1991, Volume: 71, Issue:6

    Topics: Adolescent; Adult; Aged; Analysis of Variance; Chi-Square Distribution; Dental Occlusion; Depression

1991
Improvement of chronic neurotic excoriations with oral doxepin therapy.
    International journal of dermatology, 1987, Volume: 26, Issue:8

    Topics: Administration, Oral; Aged; Chronic Disease; Depression; Dermatitis, Atopic; Doxepin; Female; Humans

1987
Antidepressants: their uses in nonpsychiatric disorders of aging.
    Geriatrics, 1986, Volume: 41, Issue:10

    Topics: Affective Symptoms; Aged; Antidepressive Agents; Chronic Disease; Colonic Diseases, Functional; Depr

1986
Cardiovascular effects of polycyclic antidepressants.
    Angiology, 1986, Volume: 37, Issue:10

    Topics: Adult; Amitriptyline; Amoxapine; Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Depression;

1986
Anticholinergic activity in the serum of patients receiving maintenance amitriptyline or doxepin therapy.
    Acta pharmacologica et toxicologica, 1985, Volume: 56, Issue:1

    Topics: Adult; Amitriptyline; Atropine; Binding Sites; Depression; Doxepin; Female; Humans; Kinetics; Male;

1985
Emotional problems during weight reduction: advantages of a combined behavior therapy and antidepressive drug therapy for obesity.
    Journal of behavior therapy and experimental psychiatry, 1985, Volume: 16, Issue:3

    Topics: Adult; Behavior Therapy; Combined Modality Therapy; Depression; Diet, Reducing; Doxepin; Female; Hum

1985
Letter: Lithium and M.R.I.H. in tardive dyskinesia.
    Lancet (London, England), 1974, Dec-14, Volume: 2, Issue:7894

    Topics: Administration, Oral; Animals; Antipsychotic Agents; Carbonates; Depression; Doxepin; Drug Therapy,

1974
Mixed anxiety-depression. Fact or myth?
    Archives of general psychiatry, 1974, Volume: 30, Issue:3

    Topics: Adult; Amitriptyline; Anxiety Disorders; Barbiturates; Chlordiazepoxide; Depression; Doxepin; Female

1974
Differences between mental disorders of French Canadians and British Canadians.
    Canadian Psychiatric Association journal, 1974, Volume: 19, Issue:3

    Topics: Adolescent; Adult; Age Factors; Aged; Alcoholism; Bipolar Disorder; Canada; Chlordiazepoxide; Cranio

1974
Doxepin in the inpatient treatment of depressive states.
    Revue roumaine de neurologie et de psychiatrie, 1974, Volume: 11, Issue:3

    Topics: Adjustment Disorders; Adult; Aged; Alcoholism; Anxiety Disorders; Depression; Doxepin; Drug Evaluati

1974
[Doxepin, a new antidepressive drug for internal clinic (author's transl)].
    Przeglad lekarski, 1974, Volume: 31, Issue:5

    Topics: Depression; Doxepin; Drug Evaluation; Humans

1974