saikosaponin d has been researched along with Depression in 13 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 6 (46.15) | 24.3611 |
| 2020's | 7 (53.85) | 2.80 |
| Authors | Studies |
|---|---|
| Bai, Z; Gao, T; Lu, Y; Tian, J; Wang, H; Wang, T; Zhang, R; Zhao, K | 1 |
| Chen, Y; Han, X; Wan, H; Yang, J; Yin, P; Yu, L; Zhang, T; Zhou, H | 1 |
| Deng, X; Du, Z; Fu, Q; Gao, S; Li, S; Liu, T; Ma, S; Ma, Y; Tang, R; Wang, W; Wang, X; Yu, J | 1 |
| Shuang, R; Tong, Y; Wang, H; Zeng, N; Zhao, G | 1 |
| Chao, B; Huang, S; Pan, J; Wang, Y; Zhang, Y | 1 |
| Huang, F; Li, XZ; Ma, SP; Pan, YW; Su, J; Wang, SQ | 1 |
| Hu, MZ; Li, YB; Liu, B; Mi, LF; Wang, AR; Zhang, ZL; Zhao, ZY; Zheng, S | 1 |
| Fang, F; Li, HW; Li, HY; Li, M; Ma, SP; Qin, TT; Qu, R; Ye, LY; Zeng, MJ; Zhao, YH | 1 |
| Chen, SJ; Chen, XQ; Dong, SQ; Li, CD; Li, CF; Liang, WN; Wang, M; Wang, SS; Yi, LT | 1 |
| Li, X; Pan, R; Song, M; Sun, X; Wang, Q; Xu, Y | 1 |
| Deng, X; Guo, L; Ma, S; Su, J; Wang, S; Xu, L | 1 |
| Gao, X; Qiao, M; Sun, P; Wei, S; Xue, L; Zhang, H | 1 |
| Cao, C; Ding, H; Liu, Y | 1 |
13 other study(ies) available for saikosaponin d and Depression
| Article | Year |
|---|---|
Inhibition of IL-6 methylation by Saikosaponin C regulates neuroinflammation to alleviate depression.
Topics: Animals; Depression; DNA Methylation; Humans; Interleukin-6; Mice; Neuroinflammatory Diseases; Tumor Necrosis Factor-alpha | 2023 |
Pharmacokinetic analysis for simultaneous quantification of Saikosaponin A- paeoniflorin in normal and poststroke depression rats: A comparative study.
Topics: Animals; Depression; Drugs, Chinese Herbal; Monoterpenes; Rats; Rats, Sprague-Dawley | 2023 |
Saikosaponin B2 ameliorates depression-induced microglia activation by inhibiting ferroptosis-mediated neuroinflammation and ER stress.
Topics: Animals; Calcium; Depression; Disease Models, Animal; Endoplasmic Reticulum Stress; Hippocampus; Lipopolysaccharides; Mice; Microglia; Neuroinflammatory Diseases; NF-kappa B; Signal Transduction; Stress, Psychological; Toll-Like Receptor 4 | 2023 |
Saikosaponin a activates tet1/dll3/notch1 signalling and promotes hippocampal neurogenesis to improve depression-like behavior in mice.
Topics: Animals; Antidepressive Agents; Depression; Hippocampus; Male; Mice; Molecular Docking Simulation; Neurogenesis; Signal Transduction | 2024 |
Saikosaponin d downregulates microRNA-155 and upregulates FGF2 to improve depression-like behaviors in rats induced by unpredictable chronic mild stress by negatively regulating NF-κB.
Topics: Animals; Behavior, Animal; Depression; Fibroblast Growth Factor 2; Hindlimb Suspension; Hippocampus; Male; MicroRNAs; Neurons; NF-kappa B; Oleanolic Acid; Rats, Sprague-Dawley; Saponins; Signal Transduction; Stress, Psychological | 2020 |
Saikosaponin-d attenuated lipopolysaccharide-induced depressive-like behaviors via inhibiting microglia activation and neuroinflammation.
Topics: Animals; Antidepressive Agents; Cell Survival; Cells, Cultured; Depression; Encephalitis; HMGB1 Protein; Lipopolysaccharides; Male; Mice, Inbred ICR; Microglia; NF-kappa B; Oleanolic Acid; Saponins; Signal Transduction; Toll-Like Receptor 4 | 2020 |
Saikosaponin A improved depression-like behavior and inhibited hippocampal neuronal apoptosis after cerebral ischemia through p-CREB/BDNF pathway.
Topics: Animals; Antidepressive Agents; Apoptosis; Behavior, Animal; Brain Ischemia; Brain-Derived Neurotrophic Factor; Cyclic AMP Response Element-Binding Protein; Dentate Gyrus; Depression; Disease Models, Animal; Hippocampus; Ischemic Stroke; Male; Oleanolic Acid; Rats; Rats, Sprague-Dawley; Recovery of Function; Saponins | 2021 |
Saikosaponin D relieves unpredictable chronic mild stress induced depressive-like behavior in rats: involvement of HPA axis and hippocampal neurogenesis.
Topics: Animals; Antidepressive Agents; Arousal; Corticosterone; Depression; Doublecortin Protein; Hippocampus; Hypothalamo-Hypophyseal System; Male; Motivation; Neurogenesis; Oleanolic Acid; Phytotherapy; Pituitary-Adrenal System; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Saponins; Stress, Psychological | 2017 |
Saikosaponin A attenuates perimenopausal depression-like symptoms by chronic unpredictable mild stress.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Brain; Brain-Derived Neurotrophic Factor; Depression; Female; Oleanolic Acid; Perimenopause; Rats; Rats, Wistar; Saponins; Stress, Psychological | 2018 |
Total Saikosaponins of Bupleurum yinchowense reduces depressive, anxiety-like behavior and increases synaptic proteins expression in chronic corticosterine-treated mice.
Topics: Animals; Antidepressive Agents; Anxiety; Behavior, Animal; Bupleurum; Corticosterone; Depression; Male; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Inbred ICR; Oleanolic Acid; Plant Extracts; Receptors, AMPA; Saponins; Signal Transduction | 2018 |
Modulation of LPA1 receptor-mediated neuronal apoptosis by Saikosaponin-d: A target involved in depression.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Cell Line, Tumor; Coculture Techniques; Depression; Dose-Response Relationship, Drug; Humans; Lysophospholipids; Mice; Mice, Inbred ICR; Neurons; Oleanolic Acid; Random Allocation; Receptors, Lysophosphatidic Acid; Saponins | 2019 |
Shu‑Yu capsule, a Traditional Chinese Medicine formulation, attenuates premenstrual syndrome depression induced by chronic stress constraint.
Topics: Animals; Body Mass Index; Depression; Drugs, Chinese Herbal; Female; Fluoxetine; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Medicine, Chinese Traditional; Oleanolic Acid; Premenstrual Syndrome; Rats; Rats, Wistar; Saponins | 2014 |
Pharmacological experimental study of the anti-depressant effect of total saikosaponins.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Depression; Disease Models, Animal; Drugs, Chinese Herbal; Hindlimb Suspension; Humans; Male; Mice; Motor Activity; Oleanolic Acid; Saponins | 2014 |