trazodone has been researched along with Depression in 107 studies
Trazodone: A serotonin uptake inhibitor that is used as an antidepressive agent. It has been shown to be effective in patients with major depressive disorders and other subsets of depressive disorders. It is generally more useful in depressive disorders associated with insomnia and anxiety. This drug does not aggravate psychotic symptoms in patients with schizophrenia or schizoaffective disorders. (From AMA Drug Evaluations Annual, 1994, p309)
trazodone : An N-arylpiperazine in which one nitrogen is substituted by a 3-chlorophenyl group, while the other is substituted by a 3-(3-oxo[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)propyl group.
Depression: Depressive states usually of moderate intensity in contrast with MAJOR DEPRESSIVE DISORDER present in neurotic and psychotic disorders.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The purpose of this study was to compare the efficacy of Trazodone hydrochloride tablets alone and in combination with press-needles in the treatment of post-stroke depression." | 9.69 | Comparison of the efficacy of Trazodone hydrochloride tablets alone and in combination with press-needles in the treatment of post-stroke depression. ( Cui, Q; Wei, W, 2023) |
| "Treatment with trazodone significantly improved global fibromyalgia severity, sleep quality, and depression, as well as pain interference with daily activities although without showing a direct effect on bodily pain." | 9.15 | Trazodone plus pregabalin combination in the treatment of fibromyalgia: a two-phase, 24-week, open-label uncontrolled study. ( Calandre, EP; Molina-Barea, R; Morillas-Arques, P; Rico-Villademoros, F; Rodriguez-Lopez, CM, 2011) |
| "This study examined the efficacy of trazodone 200 mg/day in patients with erectile dysfunction (ED) without major organic findings." | 9.09 | Trazodone: a double-blind, placebo-controlled, randomized study of its effects in patients with erectile dysfunction without major organic findings. ( Bonte, L; Declercq, G; Demyttenaere, K; Enzlin, P; Vanderborght, W; Vanderschueren, D, 2000) |
| " Twenty-eight inpatients with a diagnosis of endogenous depression received either trazodone, imipramine, or placebo." | 9.04 | Trazodone, a new antidepressant: efficacy and safety in endogenous depression. ( Kellams, JJ; Klapper, MH; Small, JG, 1979) |
| "16 patients with organic depression were treated with low doses of trazodone (100 mg/day) by i." | 9.04 | Trazodone by intravenous infusion in depressions secondary to organic disease. ( Abbruzzese, G; Albano, C; Cocito, L; Gandolfo, C; Roccatagliata, G, 1977) |
| "Trazodone was developed according to the mental pain hypothesis, which was postulated from studying patients and which proposes that depression is associated with a decreased pain threshold." | 8.77 | Trazodone: from the mental pain to the "dys-stress" hypothesis of depression. ( Silvestrini, B, 1989) |
| "A retrospective cohort study was conducted using IBM MarketScan Commercial and Medicare Supplemental Databases to identify adults with: (1) ≥1 ICD-9/ICD-10 code for depression; (2) ≥1 commonly prescribed medication for insomnia (zolpidem immediate release [IR], zolpidem extended release [ER], trazodone, or benzodiazepines); and (3) ≥12 months of eligibility before and after initiating insomnia medication." | 8.12 | Incremental health care resource use and costs among adult patients with depression and treated for insomnia with zolpidem, trazodone, or benzodiazepines. ( Amari, DT; Frech, F; Gor, D; Juday, TR; Malhotra, M; Wickwire, EM, 2022) |
| "The aim of the study was to evaluate the efficacy, tolerability, and safety of once-a day trazodone tablets (Trittico Prolong® 300 mg) in patients with moderate to severe depression in routine clinical practice." | 7.88 | Once-a-Day Trazodone in the Treatment of Depression in Routine Clinical Practice. ( Češková, E; Kellnerová, R; Šedová, M; Starobová, O, 2018) |
| "The evaluation of therapeutic efficiency and safety of using trazodone in treatment of adjustment disorders with the particular focus on dominant symptoms in this illness that is anxiety, lowering of the mood, low self-esteem, sleep disorders and also aggression level." | 7.73 | [The efficacy and safety of trazodone in the treatment of adjustment disorders--naturalistic research]. ( Florkowski, A; Gałecki, P; Zboralski, K, 2005) |
| "Trazodone (TZ) was administered to nine patients suffering from obsessive-compulsive disorder (OCD), who failed to respond to either clomipramine (CMI) or to CMI plus lithium carbonate." | 7.68 | Trazodone treatment in clomipramine-resistant obsessive-compulsive disorder. ( Aizenberg, D; Hermesh, H; Munitz, H, 1990) |
| "Acute pretreatment with clinically equivalent doses of antidepressive drugs has been observed to block D,L-5-hydroxytryptophan (5-HTP) induced behavioral depression in rats working on a food-reinforced operant schedule." | 7.67 | Postsynaptic serotonergic blockade following chronic antidepressive treatment with trazodone in an animal model of depression. ( Aprison, MH; Hendrie, HC; Hingtgen, JN, 1984) |
| "In patients suffering from endogenous depression, Trazodone caused a tendency to normalization of results of Schellong's orthostatic test, the cold pressor test, and tests of thermoregulation." | 7.65 | The influence of trazodone on the circulatory system in patients with endogenous depression. II. Influence on vascular reflexes. ( Kapelski, Z; Mrozikiewicz, A; Rajewski, A; Strzyzewski, W, 1976) |
| "Mianserin was given at a dose of 30 mg for the first 7 days followed by 60 mg daily for the remaining 5 weeks." | 6.66 | The drug treatment of depression in general practice: a comparison of nocte administration of trazodone with mianserin, dothiepin and amitriptyline. ( Blacker, R; Chapman, N; Davey, A; Shanks, NJ, 1988) |
| " Using a total side effects score to assess the incidence and severity of adverse events, the two dosing regimens were found not to be significantly different." | 6.66 | A comparison of two oral dosage regimens of 150 mg trazodone in the treatment of depression in general practice. ( Davey, A, 1988) |
| "Trazodone is a triazolopyridine derivative, chemically and pharmacologically unrelated to other currently available antidepressants." | 6.39 | Trazodone. A review of its pharmacology, therapeutic use in depression and therapeutic potential in other disorders. ( Fitton, A; Haria, M; McTavish, D, 1994) |
| "The purpose of this study was to compare the efficacy of Trazodone hydrochloride tablets alone and in combination with press-needles in the treatment of post-stroke depression." | 5.69 | Comparison of the efficacy of Trazodone hydrochloride tablets alone and in combination with press-needles in the treatment of post-stroke depression. ( Cui, Q; Wei, W, 2023) |
| "Severe psoriasis is commonly associated with depression and may be its cause." | 5.27 | Generalized pustular psoriasis precipitated by trazodone in the treatment of depression. ( Baker, H; Barth, JH, 1986) |
| "Treatment with trazodone significantly improved global fibromyalgia severity, sleep quality, and depression, as well as pain interference with daily activities although without showing a direct effect on bodily pain." | 5.15 | Trazodone plus pregabalin combination in the treatment of fibromyalgia: a two-phase, 24-week, open-label uncontrolled study. ( Calandre, EP; Molina-Barea, R; Morillas-Arques, P; Rico-Villademoros, F; Rodriguez-Lopez, CM, 2011) |
| "To test the ability of a 5HT2a/c (trazodone) antagonist, to improve depression and motor function in Parkinson' disease (PD)." | 5.14 | The use of an antagonist 5-HT2a/c for depression and motor function in Parkinson' disease. ( Rosso, AL; Vincent, MB; Werneck, AL, 2009) |
| "This study examined the efficacy of trazodone 200 mg/day in patients with erectile dysfunction (ED) without major organic findings." | 5.09 | Trazodone: a double-blind, placebo-controlled, randomized study of its effects in patients with erectile dysfunction without major organic findings. ( Bonte, L; Declercq, G; Demyttenaere, K; Enzlin, P; Vanderborght, W; Vanderschueren, D, 2000) |
| " In this equivalence study the effect of 5'-MTHF on depressive symptoms and cognitive status was compared to Trazodone (TRZ) in normofolatemic elderly patients with mild to moderate dementia and depression." | 5.07 | Oral 5'-methyltetrahydrofolic acid in senile organic mental disorders with depression: results of a double-blind multicenter study. ( Abate, G; Cucinotta, D; Diana, R; La Greca, P; Le Grazie, C; Passeri, M; Senin, U; Stramba Badiale, M; Ventura, A, 1993) |
| "Forty-seven patients with definite rheumatoid arthritis (RA) were treated in a 32 week, double blind, crossover trial of amitriptyline, desipramine, trazodone, and placebo." | 5.06 | Antidepressant analgesia in rheumatoid arthritis. ( Atwood, C; Beck, NC; Brownlee-Duffeck, M; Elliott, TR; Frank, RG; Haut, AE; Kashani, JH; Kay, DR; Parker, JC; Smith, E, 1988) |
| "This 6-week, double-blind, randomised parallel group study was carried out to assess the efficacy and tolerability of 150 mg trazodone nocte and 30-60 mg mianserin nocte in the treatment of depression in general practice." | 5.06 | The efficacy and residual effects of trazodone (150 mg nocte) and mianserin in the treatment of depressed general practice patients. ( Davey, A; Moon, CA, 1988) |
| "To establish the differential indication of trazodone and to find the predictors of its efficacy, we conducted a study in which 45 patients with major depressive disorder and 75 patients with acute schizophrenia were randomly assigned under double-blind conditions to either 400 mg trazodone daily, 150 mg amitriptyline daily, 20 mg haloperidol daily, or placebo daily." | 5.06 | Experimental examination of trazodone. ( Klieser, E; Lehmann, E, 1989) |
| "A double-blind controlled study was conducted to compare the effects of imipramine and placebo with trazodone, a new antidepressant, in 45 hospitalized patients with primary depression." | 5.05 | Trazodone, a triazolopyridine derivative, in primary depressive disorder. ( Feighner, JP, 1980) |
| "16 patients with organic depression were treated with low doses of trazodone (100 mg/day) by i." | 5.04 | Trazodone by intravenous infusion in depressions secondary to organic disease. ( Abbruzzese, G; Albano, C; Cocito, L; Gandolfo, C; Roccatagliata, G, 1977) |
| " Twenty-eight inpatients with a diagnosis of endogenous depression received either trazodone, imipramine, or placebo." | 5.04 | Trazodone, a new antidepressant: efficacy and safety in endogenous depression. ( Kellams, JJ; Klapper, MH; Small, JG, 1979) |
| " TRAZODONE: Studies conducted in patients with Alzheimer's disease, mixed type dementia, or fronto-temporal dementia have shown the efficacy of trazodone for diverse types of symptoms: sadness, emotional disorders, irritability, fear, psychomotor instability, delirant ideas." | 4.82 | [Serotonin reuptake inhibitors in depression of Alzheimer's disease and other dementias]. ( Lebert, F, 2003) |
| "Trazodone was developed according to the mental pain hypothesis, which was postulated from studying patients and which proposes that depression is associated with a decreased pain threshold." | 4.77 | Trazodone: from the mental pain to the "dys-stress" hypothesis of depression. ( Silvestrini, B, 1989) |
| "A retrospective cohort study was conducted using IBM MarketScan Commercial and Medicare Supplemental Databases to identify adults with: (1) ≥1 ICD-9/ICD-10 code for depression; (2) ≥1 commonly prescribed medication for insomnia (zolpidem immediate release [IR], zolpidem extended release [ER], trazodone, or benzodiazepines); and (3) ≥12 months of eligibility before and after initiating insomnia medication." | 4.12 | Incremental health care resource use and costs among adult patients with depression and treated for insomnia with zolpidem, trazodone, or benzodiazepines. ( Amari, DT; Frech, F; Gor, D; Juday, TR; Malhotra, M; Wickwire, EM, 2022) |
| "The aim of the study was to evaluate the efficacy, tolerability, and safety of once-a day trazodone tablets (Trittico Prolong® 300 mg) in patients with moderate to severe depression in routine clinical practice." | 3.88 | Once-a-Day Trazodone in the Treatment of Depression in Routine Clinical Practice. ( Češková, E; Kellnerová, R; Šedová, M; Starobová, O, 2018) |
| " Serotonin syndrome is a potential adverse event associated with the use of SSRIs, the combination of SSRIs and trazodone, and the combination of SSRIs and linezolid." | 3.81 | A Case of an Older Adult Patient and Drugs Associated with Serotonin Syndrome. ( Nguyen, T; Sin, B, 2015) |
| " In this report, we describe a 15-year-old adolescent girl who experienced continued delirium 5 days after an overdose of quetiapine, trazodone, and clonidine." | 3.76 | Prolonged delirium after quetiapine overdose. ( Pedapati, EV; Rhyee, SH; Thompson, J, 2010) |
| "The evaluation of therapeutic efficiency and safety of using trazodone in treatment of adjustment disorders with the particular focus on dominant symptoms in this illness that is anxiety, lowering of the mood, low self-esteem, sleep disorders and also aggression level." | 3.73 | [The efficacy and safety of trazodone in the treatment of adjustment disorders--naturalistic research]. ( Florkowski, A; Gałecki, P; Zboralski, K, 2005) |
| "Trazodone (TZ) was administered to nine patients suffering from obsessive-compulsive disorder (OCD), who failed to respond to either clomipramine (CMI) or to CMI plus lithium carbonate." | 3.68 | Trazodone treatment in clomipramine-resistant obsessive-compulsive disorder. ( Aizenberg, D; Hermesh, H; Munitz, H, 1990) |
| " However, we treated three patients who experienced palinopsia as an isolated symptom, apparently as a side effect of trazodone hydrochloride therapy for depression." | 3.68 | Trazodone-induced palinopsia. ( Hughes, MS; Lessell, S, 1990) |
| "Acute pretreatment with clinically equivalent doses of antidepressive drugs has been observed to block D,L-5-hydroxytryptophan (5-HTP) induced behavioral depression in rats working on a food-reinforced operant schedule." | 3.67 | Postsynaptic serotonergic blockade following chronic antidepressive treatment with trazodone in an animal model of depression. ( Aprison, MH; Hendrie, HC; Hingtgen, JN, 1984) |
| "Trazodone and tricyclics share similar activity towards the core symptoms of depression, whereas their effects on neurohumoral transmission tend to be opposite." | 3.67 | Beyond the limits of typical antidepressants. ( Silvestrini, B, 1988) |
| "Case reports are presented of two depressed patients with probable bipolar disorder who did not respond to trazodone but developed mania when this drug was abruptly replaced with imipramine." | 3.67 | Mania following change from trazodone to imipramine. ( Haggerty, JJ; Jackson, R, 1985) |
| " The results indicate that chronic administration of imipramine or of electroshock led to the abolition of the behavioural depression and of the EEG synchronisation induced by clonidine." | 3.66 | Effects of chronic treatment with imipramine, trazodone and electroshock on the behavioural and electroencephalographic modifications induced by clonidine in the rat. ( Passarelli, F; Scotti de Carolis, A, 1983) |
| "An analysis was made of the occurrence of anticholinergic side effects in 15 multicenter studies of 379 patients with endogenous depression who received either trazodone, imipramine, or placebo." | 3.66 | Lack of anticholinergic side effects with a new antidepressent--trazodone. ( Gershon, S; Newton, R, 1980) |
| "In patients suffering from endogenous depression, Trazodone caused a tendency to normalization of results of Schellong's orthostatic test, the cold pressor test, and tests of thermoregulation." | 3.65 | The influence of trazodone on the circulatory system in patients with endogenous depression. II. Influence on vascular reflexes. ( Kapelski, Z; Mrozikiewicz, A; Rajewski, A; Strzyzewski, W, 1976) |
| "Fifty-four pregnant women with insomnia were randomly assigned to trazodone, diphenhydramine, or placebo treatment." | 2.78 | Insomnia treatment in the third trimester of pregnancy reduces postpartum depression symptoms: a randomized clinical trial. ( Emamian, F; Ghadami, MR; Khazaie, H; Knight, DC; Tahmasian, M, 2013) |
| "Chronic pain is refractory to most currently marketed regimens." | 2.66 | Chronic pain: hypothesized mechanism and rationale for treatment. ( Gershon, S, 1986) |
| "Mianserin was given at a dose of 30 mg for the first 7 days followed by 60 mg daily for the remaining 5 weeks." | 2.66 | The drug treatment of depression in general practice: a comparison of nocte administration of trazodone with mianserin, dothiepin and amitriptyline. ( Blacker, R; Chapman, N; Davey, A; Shanks, NJ, 1988) |
| "Antidepressant drugs have been used to treat tinnitus in patients with and without depressive symptoms." | 2.48 | Antidepressants for patients with tinnitus. ( Baldo, P; Cecco, S; Doree, C; McFerran, D; Molin, P, 2012) |
| "Such approach to treatment of insomnia in depressed patients protects them against dependence on hypnotic drugs." | 2.47 | [The effects of antidepressants on sleep in depressed patients with particular reference to trazodone in comparison to agomelatine, amitriptyline, doxepin, mianserine and mirtazapine]. ( Wichniak, A; Wierzbicka, A, 2011) |
| "Trazodone is an sedative antidepressant, acting quickly, efficiently, safely, with a small number of adverse reactions and proven effective in the treatment of insomnia." | 2.46 | [Efficacy of trazodone in the treatment of insomnia]. ( Florkowski, A; Gałecki, P; Talarowska, M, 2010) |
| "Trazodone is a triazolopyridine derivative, chemically and pharmacologically unrelated to other currently available antidepressants." | 2.39 | Trazodone. A review of its pharmacology, therapeutic use in depression and therapeutic potential in other disorders. ( Fitton, A; Haria, M; McTavish, D, 1994) |
| " Side effects were measured with the Udvalg for Kliniske Undersogelser Side Effect Rating Scale (UKU); the total score and UKU subscales were considered." | 1.91 | Characterisation of medication side effects in patients with mostly resistant depression in a real-world setting. ( De Ronchi, D; Fabbri, C; Ferentinos, P; Kasper, S; Mendlewicz, J; Montgomery, S; Panariello, F; Rujescu, D; Serretti, A; Souery, D; Zohar, J, 2023) |
| " Mianserin and mirtazapine (separately) induced dose-dependent antinociception, each one yielding a biphasic dose-response curve, and they were antagonized by naloxone." | 1.91 | Treatment-Resistant Depression (TRD): Is the Opioid System Involved? ( Keidan, L; Pick, CG; Schreiber, S, 2023) |
| "It is licensed to treat depression, but it is also commonly used off-label to treat insomnia." | 1.48 | Evaluating the dose-dependent mechanism of action of trazodone by estimation of occupancies for different brain neurotransmitter targets. ( Settimo, L; Taylor, D, 2018) |
| " Optimal follow-up visits and adequate antidepressant dosing was associated with better adherence during both treatment phases, as was use of other psychotropic medications." | 1.37 | Factors associated with antidepressant adherence for Medicaid-enrolled children and adolescents. ( Bridge, JA; Campo, JV; Fontanella, CA; Marcus, SC, 2011) |
| "Trazodone is a second-generation antidepressant with serotonin antagonist activity." | 1.35 | HPLC analysis of the antidepressant trazodone and its main metabolite m-CPP in human plasma. ( Amore, M; Colliva, C; Fanali, S; Mercolini, L; Raggi, MA, 2008) |
| "Trazodone was frequently recommended for sleep problems." | 1.34 | Reasons for antidepressant prescriptions in Canada. ( Carter, B; Esposito, E; Patten, SB, 2007) |
| "Trazodone is a unique antidepressant, which blocks the postsynaptic serotonin (5-HT) receptors, 5-HT(2A) and 5-HT(2C), and weakly inhibits presynaptic 5-HT transporters." | 1.34 | Does trazodone have a role in palliating symptoms? ( Davis, MP, 2007) |
| "The seizure was successfully treated with benzodiazepines." | 1.32 | Seizure secondary to citalopram overdose. ( Cuenca, PJ; Hoefle, JD; Holt, KR, 2004) |
| "Severe psoriasis is commonly associated with depression and may be its cause." | 1.27 | Generalized pustular psoriasis precipitated by trazodone in the treatment of depression. ( Baker, H; Barth, JH, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 54 (50.47) | 18.7374 |
| 1990's | 14 (13.08) | 18.2507 |
| 2000's | 18 (16.82) | 29.6817 |
| 2010's | 15 (14.02) | 24.3611 |
| 2020's | 6 (5.61) | 2.80 |
| Authors | Studies |
|---|---|
| Wickwire, EM | 1 |
| Amari, DT | 1 |
| Juday, TR | 1 |
| Frech, F | 1 |
| Gor, D | 1 |
| Malhotra, M | 1 |
| Panariello, F | 1 |
| Kasper, S | 2 |
| Zohar, J | 1 |
| Souery, D | 1 |
| Montgomery, S | 1 |
| Ferentinos, P | 1 |
| Rujescu, D | 1 |
| Mendlewicz, J | 1 |
| De Ronchi, D | 1 |
| Serretti, A | 1 |
| Fabbri, C | 1 |
| Cui, Q | 1 |
| Wei, W | 1 |
| Schreiber, S | 2 |
| Keidan, L | 1 |
| Pick, CG | 2 |
| Elhesaisy, N | 1 |
| Swidan, S | 1 |
| Leng, Y | 1 |
| Diem, SJ | 1 |
| Stone, KL | 1 |
| Yaffe, K | 1 |
| Settimo, L | 1 |
| Taylor, D | 1 |
| Češková, E | 1 |
| Šedová, M | 1 |
| Kellnerová, R | 1 |
| Starobová, O | 1 |
| Khazaie, H | 1 |
| Ghadami, MR | 1 |
| Knight, DC | 1 |
| Emamian, F | 1 |
| Tahmasian, M | 1 |
| Osváth, P | 1 |
| Tang, C | 1 |
| Yu, R | 1 |
| Iaboni, A | 1 |
| Seitz, DP | 1 |
| Fischer, HD | 1 |
| Diong, CC | 1 |
| Rochon, PA | 1 |
| Flint, AJ | 1 |
| Nguyen, T | 1 |
| Sin, B | 1 |
| Werneck, AL | 1 |
| Rosso, AL | 1 |
| Vincent, MB | 1 |
| Detry, O | 1 |
| Delwaide, J | 1 |
| De Roover, A | 1 |
| Hans, MF | 1 |
| Delbouille, MH | 1 |
| Monard, J | 1 |
| Honoré, P | 1 |
| Stahl, SM | 1 |
| Gałecki, P | 2 |
| Florkowski, A | 2 |
| Talarowska, M | 1 |
| Rhyee, SH | 1 |
| Pedapati, EV | 1 |
| Thompson, J | 1 |
| Calandre, EP | 1 |
| Morillas-Arques, P | 1 |
| Molina-Barea, R | 1 |
| Rodriguez-Lopez, CM | 1 |
| Rico-Villademoros, F | 1 |
| Fontanella, CA | 1 |
| Bridge, JA | 1 |
| Marcus, SC | 1 |
| Campo, JV | 1 |
| Wichniak, A | 1 |
| Wierzbicka, A | 1 |
| Clark, MS | 1 |
| Smith, PO | 1 |
| Jamieson, B | 1 |
| Baldo, P | 1 |
| Doree, C | 1 |
| Molin, P | 1 |
| McFerran, D | 1 |
| Cecco, S | 1 |
| Lacy, T | 1 |
| Mathis, M | 1 |
| Lebert, F | 1 |
| Cuenca, PJ | 1 |
| Holt, KR | 1 |
| Hoefle, JD | 1 |
| Zboralski, K | 1 |
| Winkler, D | 1 |
| Ortner, R | 1 |
| Pjrek, E | 1 |
| Aschauer, H | 1 |
| Davis, MP | 1 |
| Patten, SB | 1 |
| Esposito, E | 1 |
| Carter, B | 1 |
| Dattilo, PB | 1 |
| Nordin, C | 1 |
| Mercolini, L | 1 |
| Colliva, C | 1 |
| Amore, M | 1 |
| Fanali, S | 1 |
| Raggi, MA | 1 |
| Koval'chuk, VV | 1 |
| Burchinskiĭ, SG | 1 |
| Aronoff, GM | 1 |
| Lydiard, RB | 2 |
| Pottash, AL | 1 |
| Gold, MS | 1 |
| Kane, JM | 1 |
| Lieberman, J | 1 |
| Leonard, BE | 1 |
| Gever, LN | 1 |
| Hingtgen, JN | 1 |
| Hendrie, HC | 1 |
| Aprison, MH | 1 |
| Passarelli, F | 1 |
| Scotti de Carolis, A | 1 |
| Mann, SC | 1 |
| Walker, MM | 1 |
| Messenger, GG | 1 |
| Greenstein, RA | 1 |
| Feighner, JP | 1 |
| Al-Yassiri, MM | 2 |
| Bridges, PK | 3 |
| Murphy, JE | 1 |
| Ankier, SI | 4 |
| Silvestrini, B | 3 |
| Richards, HH | 1 |
| Midha, RN | 1 |
| Miller, S | 1 |
| Bobon, DP | 1 |
| Lapierre, YD | 1 |
| Lottin, T | 1 |
| Gershon, S | 2 |
| Newton, R | 1 |
| Gerner, R | 2 |
| Estabrook, W | 2 |
| Steuer, J | 2 |
| Jarvik, L | 2 |
| Waltuch, L | 1 |
| Kakkar, P | 1 |
| Klein, DF | 1 |
| Pierce, D | 1 |
| Haria, M | 1 |
| Fitton, A | 1 |
| McTavish, D | 1 |
| Jackson, CW | 1 |
| Morton, WA | 1 |
| Passeri, M | 1 |
| Cucinotta, D | 1 |
| Abate, G | 1 |
| Senin, U | 1 |
| Ventura, A | 1 |
| Stramba Badiale, M | 1 |
| Diana, R | 1 |
| La Greca, P | 1 |
| Le Grazie, C | 1 |
| Pescatori, ES | 1 |
| Engelman, JC | 1 |
| Davis, G | 1 |
| Goldstein, I | 1 |
| Otani, K | 2 |
| Tybring, G | 1 |
| Mihara, K | 2 |
| Yasui, N | 1 |
| Kaneko, S | 2 |
| Ohkubo, T | 1 |
| Nagasaki, T | 1 |
| Sugawara, K | 1 |
| Lawlor, B | 1 |
| Razavi, D | 1 |
| Kormoss, N | 1 |
| Collard, A | 1 |
| Farvacques, C | 1 |
| Delvaux, N | 1 |
| Enzlin, P | 1 |
| Vanderschueren, D | 1 |
| Bonte, L | 1 |
| Vanderborght, W | 1 |
| Declercq, G | 1 |
| Demyttenaere, K | 1 |
| Lantz, MS | 1 |
| Kondo, T | 1 |
| Suzuki, A | 1 |
| Yasui-Furukori, N | 1 |
| Ono, S | 1 |
| Darko, W | 1 |
| Guharoy, R | 1 |
| Rose, F | 1 |
| Lehman, D | 1 |
| Pappas, V | 1 |
| Fukunishi, I | 1 |
| Kitaoka, T | 1 |
| Shirai, T | 1 |
| Kino, K | 1 |
| Kanematsu, E | 1 |
| Sato, Y | 1 |
| Roccatagliata, G | 3 |
| Abbruzzese, G | 1 |
| Albano, C | 1 |
| Cocito, L | 1 |
| Gandolfo, C | 2 |
| Kellams, JJ | 1 |
| Klapper, MH | 1 |
| Small, JG | 1 |
| Trapp, GA | 1 |
| Handorf, CR | 1 |
| Larach, V | 1 |
| Vinar, O | 1 |
| Topiar, A | 1 |
| Muronová, J | 1 |
| Cammarata, S | 1 |
| De Martini, I | 1 |
| Arcuri, T | 1 |
| Loeb, C | 1 |
| Besio, G | 1 |
| Allori, L | 1 |
| Catanese, B | 1 |
| Cioli, V | 1 |
| Interdonato, N | 1 |
| Piccione, M | 2 |
| Decina, P | 1 |
| Dionisio, A | 1 |
| Agnoli, A | 1 |
| Nicoletti, F | 1 |
| Mrozikiewicz, A | 2 |
| Strzyzewski, W | 2 |
| Kapelski, Z | 2 |
| Sydor, L | 1 |
| Rajewski, A | 1 |
| Lehmann, HE | 1 |
| Ban, TA | 2 |
| Schwartz, GV | 1 |
| Putzolu, S | 3 |
| Pecknold, JC | 3 |
| Baiocchi, L | 1 |
| Grad, B | 1 |
| Naveillan, P | 1 |
| Cohen, LJ | 1 |
| Grothe, DR | 1 |
| Hermesh, H | 1 |
| Aizenberg, D | 1 |
| Munitz, H | 1 |
| Metz, A | 1 |
| Shader, RI | 1 |
| Boylan, K | 1 |
| Moon, CA | 2 |
| Laws, D | 1 |
| Stott, PC | 1 |
| Hayes, G | 1 |
| Hughes, MS | 1 |
| Lessell, S | 1 |
| Cazzullo, CL | 1 |
| Klieser, E | 1 |
| Lehmann, E | 1 |
| Blacker, R | 1 |
| Shanks, NJ | 1 |
| Chapman, N | 1 |
| Davey, A | 3 |
| Frank, RG | 1 |
| Kashani, JH | 1 |
| Parker, JC | 1 |
| Beck, NC | 1 |
| Brownlee-Duffeck, M | 1 |
| Elliott, TR | 1 |
| Haut, AE | 1 |
| Atwood, C | 1 |
| Smith, E | 1 |
| Kay, DR | 1 |
| Bucknall, C | 1 |
| Brooks, D | 1 |
| Curry, PV | 1 |
| Bouras, N | 1 |
| Price, LH | 1 |
| Charney, DS | 1 |
| Heninger, GR | 1 |
| Ferguson, S | 1 |
| Barth, JH | 1 |
| Baker, H | 1 |
| Ather, SA | 1 |
| Middleton, RS | 1 |
| Haggerty, JJ | 1 |
| Jackson, R | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| [NCT05753943] | 0 participants | Expanded Access | No longer available | ||||
| Open Label Trial Concerning the Effectiveness of Trazodone in the Treatment of Fibromyalgia (Phase I) and Its Augmentation With Pregabalin in Trazodone Partial Responders (Phase II)[NCT00791739] | Phase 4 | 66 participants (Actual) | Interventional | 2008-04-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
15 reviews available for trazodone and Depression
| Article | Year |
|---|---|
[Current treatment of depression and agitation in the elderly -- clinical use of trazodone].
Topics: Aged; Aged, 80 and over; Anti-Anxiety Agents; Antidepressive Agents; Antidepressive Agents, Second-G | 2013 |
Mechanism of action of trazodone: a multifunctional drug.
Topics: Antidepressive Agents; Depression; Dose-Response Relationship, Drug; Humans; Models, Biological; Neu | 2009 |
[Efficacy of trazodone in the treatment of insomnia].
Topics: Antidepressive Agents, Second-Generation; Depression; Humans; Sleep Initiation and Maintenance Disor | 2010 |
[The effects of antidepressants on sleep in depressed patients with particular reference to trazodone in comparison to agomelatine, amitriptyline, doxepin, mianserine and mirtazapine].
Topics: Amitriptyline; Antidepressive Agents; Depression; Doxepin; Humans; Mianserin; Mirtazapine; Sleep; Sl | 2011 |
Antidepressants for patients with tinnitus.
Topics: Amitriptyline; Antidepressive Agents; Depression; Humans; Nortriptyline; Paroxetine; Randomized Cont | 2012 |
[Serotonin reuptake inhibitors in depression of Alzheimer's disease and other dementias].
Topics: Aged; Alzheimer Disease; Anti-Anxiety Agents; Antidepressive Agents, Second-Generation; Clinical Tri | 2003 |
[Biochemical aspects of using antidepressants in late middle age and the elderly (review)].
Topics: Age Factors; Aged; Aging; Antidepressive Agents; Catechol O-Methyltransferase; Depression; Depressiv | 1983 |
The efficacy of amoxapine, maprotiline, and trazodone in comparison to imipramine and amitriptyline: a review of the literature.
Topics: Amitriptyline; Amoxapine; Anthracenes; Clinical Trials as Topic; Depression; Dibenzoxazepines; Human | 1984 |
Pharmacological properties of some "second generation" antidepressant drugs.
Topics: Animals; Antidepressive Agents; Brompheniramine; Depression; Electroconvulsive Therapy; Humans; Mian | 1980 |
Trazodone--a new antidepressant.
Topics: Animals; Antidepressive Agents; Depression; Drug Interactions; Hemodynamics; Humans; Kinetics; Piper | 1981 |
Trazodone--a new type of antidepressant: a discussion of pharmacological data and their clinical implications.
Topics: Animals; Brain; Depression; Humans; Imipramine; Piperazines; Receptors, Serotonin; Trazodone | 1982 |
Trazodone. A review of its pharmacology, therapeutic use in depression and therapeutic potential in other disorders.
Topics: Aged; Aged, 80 and over; Depression; Female; Humans; Male; Middle Aged; Sleep Initiation and Mainten | 1994 |
Major depression: its recognition and treatment. Part 2. Second-generation and newer antidepressants.
Topics: Antidepressive Agents; Bupropion; Clomipramine; Depression; Female; Fluoxetine; Humans; Male; Maprot | 1992 |
Trazodone: from the mental pain to the "dys-stress" hypothesis of depression.
Topics: Adrenergic alpha-Antagonists; Depression; Humans; Pain; Sensory Thresholds; Trazodone | 1989 |
New treatment for anxious depression syndrome.
Topics: Anxiety; Depression; Humans; Syndrome; Trazodone | 1989 |
33 trials available for trazodone and Depression
| Article | Year |
|---|---|
Comparison of the efficacy of Trazodone hydrochloride tablets alone and in combination with press-needles in the treatment of post-stroke depression.
Topics: Brain-Derived Neurotrophic Factor; Depression; Humans; Needles; Serotonin; Stroke; Tablets; Trazodon | 2023 |
Insomnia treatment in the third trimester of pregnancy reduces postpartum depression symptoms: a randomized clinical trial.
Topics: Actigraphy; Adult; Antidepressive Agents, Second-Generation; Depression; Depression, Postpartum; Dip | 2013 |
The use of an antagonist 5-HT2a/c for depression and motor function in Parkinson' disease.
Topics: Aged; Depression; Female; Humans; Male; Middle Aged; Parkinson Disease; Psychiatric Status Rating Sc | 2009 |
Trazodone plus pregabalin combination in the treatment of fibromyalgia: a two-phase, 24-week, open-label uncontrolled study.
Topics: Adult; Analgesics; Analysis of Variance; Anti-Anxiety Agents; Antidepressive Agents, Second-Generati | 2011 |
[Pharmacologic correction of psycho-emotive disorders in the rehabilitation of patients after removal of brain tumors].
Topics: Adult; Alprazolam; Amitriptyline; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Brain Neoplas | 2007 |
Speed of onset of action of the newer antidepressants.
Topics: Amitriptyline; Amoxapine; Antidepressive Agents; Clinical Trials as Topic; Depression; Depressive Di | 1984 |
The efficacy of amoxapine, maprotiline, and trazodone in comparison to imipramine and amitriptyline: a review of the literature.
Topics: Amitriptyline; Amoxapine; Anthracenes; Clinical Trials as Topic; Depression; Dibenzoxazepines; Human | 1984 |
Trazodone, a triazolopyridine derivative, in primary depressive disorder.
Topics: Adolescent; Adult; Aged; Clinical Trials as Topic; Depression; Double-Blind Method; Female; Humans; | 1980 |
Trazodone efficacy and safety in endogenous depression: a double blind comparison with imipramine.
Topics: Adult; Clinical Trials as Topic; Depression; Double-Blind Method; Female; Humans; Imipramine; Male; | 1980 |
An evaluation of trazodone in the treatment of depression.
Topics: Adolescent; Adult; Aged; Amitriptyline; Clinical Trials as Topic; Depression; Double-Blind Method; D | 1980 |
A double-blind study of trazodone and mianserin in the treatment of depression in general practice.
Topics: Adolescent; Adult; Aged; Clinical Trials as Topic; Depression; Diazepam; Dibenzazepines; Dose-Respon | 1982 |
Treatment of geriatric depression with trazodone, imipramine, and placebo: a double-blind study.
Topics: Aged; Depression; Double-Blind Method; Female; Humans; Imipramine; Male; Middle Aged; Piperazines; P | 1980 |
Oral 5'-methyltetrahydrofolic acid in senile organic mental disorders with depression: results of a double-blind multicenter study.
Topics: Administration, Oral; Aged; Aged, 80 and over; Alzheimer Disease; Cognition; Dementia, Multi-Infarct | 1993 |
Comparative study of the efficacy and safety of trazodone versus clorazepate in the treatment of adjustment disorders in cancer patients: a pilot study.
Topics: Adjustment Disorders; Adult; Aged; Anti-Anxiety Agents; Anxiety; Breast Neoplasms; Clorazepate Dipot | 1999 |
Trazodone: a double-blind, placebo-controlled, randomized study of its effects in patients with erectile dysfunction without major organic findings.
Topics: Adolescent; Adult; Aged; Antidepressive Agents, Second-Generation; Depression; Double-Blind Method; | 2000 |
Trazodone by intravenous infusion in depressions secondary to organic disease.
Topics: Adult; Aged; Clinical Trials as Topic; Depression; Female; Humans; Hydroxyindoleacetic Acid; Infusio | 1977 |
Trazodone, a new antidepressant: efficacy and safety in endogenous depression.
Topics: Adult; Aged; Anxiety; Clinical Trials as Topic; Depression; Double-Blind Method; Female; Humans; Imi | 1979 |
Trazodone in the treatment of depressed inpatients.
Topics: Adult; Aged; Clinical Trials as Topic; Depression; Double-Blind Method; Humans; Male; Middle Aged; P | 1979 |
[Fast-acting antidepressive agents: comparison of trazodone and desipramine in a controlled double-blind trial].
Topics: Adult; Aged; Clinical Trials as Topic; Depression; Desipramine; Drug Evaluation; Female; Humans; Mal | 1975 |
[Clinical trial of a new perparation with psychotropic action].
Topics: Adult; Aged; Anxiety; Clinical Trials as Topic; Depression; Drug Evaluation; Female; Humans; Male; M | 1975 |
Psychotherapeutic profile of a new psychoactive drug trazodone (AF-1161).
Topics: Adult; Aged; Clinical Trials as Topic; Depression; Female; Humans; Male; Mental Disorders; Middle Ag | 1975 |
Proceedings: Trazodone: clinical and biochemical studies II. Blood levels and therapeutic responsiveness.
Topics: Adult; Clinical Trials as Topic; Depression; Female; Humans; Male; Middle Aged; Piperazines; Trazodo | 1976 |
Proceedings: Trazodone: clinical and biochemical studies III. Dexamethasone suppression test results and therapeutic responsiveness.
Topics: Adult; Clinical Trials as Topic; Depression; Dexamethasone; Female; Humans; Hydrocortisone; Male; Mi | 1976 |
Proceedings: Trazodone: clinical and biochemical studies I. An uncontrolled clinical trial in depression.
Topics: Adult; Clinical Trials as Topic; Depression; Female; Humans; Male; Middle Aged; Piperazines; Psychia | 1976 |
Efficacy and tolerability of controlled-release trazodone in depression: a large multicentre study in general practice.
Topics: Adolescent; Adult; Aged; Delayed-Action Preparations; Depression; Double-Blind Method; Female; Human | 1990 |
Experimental examination of trazodone.
Topics: Adult; Amitriptyline; Anxiety; Depression; Depressive Disorder; Double-Blind Method; Female; Haloper | 1989 |
Chronic pain: hypothesized mechanism and rationale for treatment.
Topics: Antidepressive Agents; Brain; Chronic Disease; Clinical Trials as Topic; Depression; Humans; Neurotr | 1986 |
The drug treatment of depression in general practice: a comparison of nocte administration of trazodone with mianserin, dothiepin and amitriptyline.
Topics: Adolescent; Adult; Aged; Amitriptyline; Antidepressive Agents; Clinical Trials as Topic; Depression; | 1988 |
A comparison of two oral dosage regimens of 150 mg trazodone in the treatment of depression in general practice.
Topics: Administration, Oral; Adolescent; Adult; Aged; Clinical Trials as Topic; Depression; Double-Blind Me | 1988 |
The efficacy and residual effects of trazodone (150 mg nocte) and mianserin in the treatment of depressed general practice patients.
Topics: Adolescent; Adult; Aged; Clinical Trials as Topic; Depression; Double-Blind Method; Drug Tolerance; | 1988 |
Antidepressant analgesia in rheumatoid arthritis.
Topics: Aged; Amitriptyline; Antidepressive Agents; Arthritis, Rheumatoid; Depression; Desipramine; Double-B | 1988 |
Mianserin and trazodone for cardiac patients with depression.
Topics: Adult; Aged; Clinical Trials as Topic; Depression; Double-Blind Method; Female; Heart Diseases; Hemo | 1988 |
A double-blind evaluation of trazodone in the treatment of depression in the elderly.
Topics: Aged; Amitriptyline; Clinical Trials as Topic; Depression; Double-Blind Method; Female; Humans; Male | 1985 |
60 other studies available for trazodone and Depression
| Article | Year |
|---|---|
Incremental health care resource use and costs among adult patients with depression and treated for insomnia with zolpidem, trazodone, or benzodiazepines.
Topics: Adult; Aged; Benzodiazepines; Delivery of Health Care; Depression; Female; Health Care Costs; Humans | 2022 |
Characterisation of medication side effects in patients with mostly resistant depression in a real-world setting.
Topics: Anxiety Disorders; Depression; Depressive Disorder, Treatment-Resistant; Drug-Related Side Effects a | 2023 |
Treatment-Resistant Depression (TRD): Is the Opioid System Involved?
Topics: Analgesics, Opioid; Animals; Antidepressive Agents; Depression; Dose-Response Relationship, Drug; Fl | 2023 |
Trazodone and mirtazapine: A possible opioid involvement in their use (at low dose) for sleep?
Topics: Analgesics; Analgesics, Opioid; Animals; Antidepressive Agents; Depression; Disease Models, Animal; | 2020 |
Trazodone Loaded Lipid Core Poly (ε-caprolactone) Nanocapsules: Development, Characterization and in Vivo Antidepressant Effect Evaluation.
Topics: Animals; Antidepressive Agents; Delayed-Action Preparations; Depression; Disease Models, Animal; Dru | 2020 |
Antidepressant Use and Cognitive Outcomes in Very Old Women.
Topics: Aged; Aged, 80 and over; Antidepressive Agents; Antidepressive Agents, Tricyclic; Cognition; Cogniti | 2018 |
Evaluating the dose-dependent mechanism of action of trazodone by estimation of occupancies for different brain neurotransmitter targets.
Topics: Animals; Antidepressive Agents; Brain; Dementia; Depression; Depressive Disorder; Humans; Hypnotics | 2018 |
Once-a-Day Trazodone in the Treatment of Depression in Routine Clinical Practice.
Topics: Adult; Aged; Antidepressive Agents, Second-Generation; Depression; Drug Administration Schedule; Dru | 2018 |
Adult-onset idiopathic isolated central hypothyroidism: a case report and literature review.
Topics: Adrenergic alpha-1 Receptor Agonists; Antidepressive Agents, Second-Generation; Depression; Female; | 2015 |
Initiation of Antidepressant Medication After Hip Fracture in Community-Dwelling Older Adults.
Topics: Aged; Aged, 80 and over; Antidepressive Agents; Databases, Factual; Depression; Female; Hip Fracture | 2015 |
A Case of an Older Adult Patient and Drugs Associated with Serotonin Syndrome.
Topics: Aged, 80 and over; Depression; Drug Interactions; Humans; Linezolid; Selective Serotonin Reuptake In | 2015 |
Fulminant hepatic failure induced by venlafaxine and trazodone therapy: a case report.
Topics: Aspartate Aminotransferases; Bilirubin; Cyclohexanols; Depression; Factor V; Female; Humans; Interna | 2009 |
Prolonged delirium after quetiapine overdose.
Topics: Adolescent; Antipsychotic Agents; Cholinergic Antagonists; Clonidine; Cytochrome P-450 CYP3A; Deliri | 2010 |
Factors associated with antidepressant adherence for Medicaid-enrolled children and adolescents.
Topics: Adolescent; Antidepressive Agents; Child; Child, Preschool; Databases, Factual; Depression; Female; | 2011 |
FPIN's clinical inquiries: Antidepressants for the treatment of insomnia in patients with depression.
Topics: Amitriptyline; Antidepressive Agents; Antidepressive Agents, Tricyclic; Depression; Dose-Response Re | 2011 |
Dissociative symptoms from combined treatment with sertraline and trazodone.
Topics: Adult; Antidepressive Agents; Depression; Dissociative Disorders; Dose-Response Relationship, Drug; | 2003 |
Seizure secondary to citalopram overdose.
Topics: Adenosine; Adult; Anti-Arrhythmia Agents; Anticonvulsants; Antidepressive Agents, Second-Generation; | 2004 |
[The efficacy and safety of trazodone in the treatment of adjustment disorders--naturalistic research].
Topics: Adjustment Disorders; Adult; Affect; Aggression; Anxiety; Depression; Female; Humans; Male; Psychiat | 2005 |
Trazodone-induced cardiac arrhythmias: a report of two cases.
Topics: Aged; Antidepressive Agents, Second-Generation; Arrhythmias, Cardiac; Depression; Female; Humans; Ma | 2006 |
Does trazodone have a role in palliating symptoms?
Topics: Antidepressive Agents, Second-Generation; Depression; Drug Interactions; Fluoxetine; Humans; Neoplas | 2007 |
Reasons for antidepressant prescriptions in Canada.
Topics: Antidepressive Agents; Antidepressive Agents, Tricyclic; Canada; Databases, Factual; Depression; Hum | 2007 |
Prolonged QT associated with an overdose of trazodone.
Topics: Adult; Antidepressive Agents, Second-Generation; Bupropion; Depression; Drug Overdose; Electrocardio | 2007 |
HPLC analysis of the antidepressant trazodone and its main metabolite m-CPP in human plasma.
Topics: Acetonitriles; Antidepressive Agents; Buffers; Chromatography, High Pressure Liquid; Depression; Dru | 2008 |
Trazodone associated with priapism.
Topics: Depression; Humans; Male; Piperazines; Priapism; Trazodone | 1984 |
Three new antidepressants amoxapine, maprotiline, and trazodone.
Topics: Amoxapine; Antidepressive Agents; Depression; Humans; Maprotiline; Trazodone | 1983 |
Postsynaptic serotonergic blockade following chronic antidepressive treatment with trazodone in an animal model of depression.
Topics: 5-Hydroxytryptophan; Amitriptyline; Animals; Depression; Disease Models, Animal; Humans; Male; Methy | 1984 |
Effects of chronic treatment with imipramine, trazodone and electroshock on the behavioural and electroencephalographic modifications induced by clonidine in the rat.
Topics: Animals; Behavior, Animal; Brain; Clonidine; Depression; Disease Models, Animal; Electroencephalogra | 1983 |
Leukocytoclastic vasculitis secondary to trazodone treatment.
Topics: Depression; Humans; Male; Middle Aged; Piperazines; Trazodone; Vasculitis, Leukocytoclastic, Cutaneo | 1984 |
Validity and sensitivity of the french version of the Zerssen BfS/BfS' self-rating mood scale during treatment with trazodone and amitriptyline.
Topics: Adolescent; Adult; Amitriptyline; Canada; Depression; Female; Humans; Male; Middle Aged; Piperazines | 1981 |
Lack of anticholinergic side effects with a new antidepressent--trazodone.
Topics: Adult; Aged; Constipation; Depression; Double-Blind Method; Female; Humans; Imipramine; Male; Middle | 1980 |
A placebo-controlled double-blind study of imipramine and trazodone in geriatric depression.
Topics: Age Factors; Aged; Depression; Double-Blind Method; Female; Humans; Imipramine; Male; Middle Aged; P | 1980 |
Clinical and biological aspects of depression in the elderly.
Topics: Aged; Dementia; Depression; Doxepin; Humans; Imipramine; Methylphenidate; Middle Aged; Trazodone | 1980 |
A comparison of trazodone and dothiepin in depression.
Topics: Adult; Aged; Depression; Dibenzothiepins; Dothiepin; Female; Humans; Male; Middle Aged; Piperazines; | 1980 |
Pharmacologic management of obsessive-compulsive disorder.
Topics: 1-Naphthylamine; Antidepressive Agents; Anxiety Disorders; Clomipramine; Depression; Dopamine; Fluox | 1994 |
Priapism of the clitoris: a case report following trazodone use.
Topics: Adjustment Disorders; Adult; Clitoris; Depression; Female; Fluoxetine; Humans; Muscle Contraction; M | 1993 |
Correlation between steady-state plasma concentrations of mianserin and trazodone in depressed patients.
Topics: Antidepressive Agents, Second-Generation; Cytochrome P-450 CYP2D6; Depression; Female; Humans; Male; | 1998 |
'The use of selective serotonin reuptake inhibitors for depression and psychosis complicating dementia'--1997, 12, 519-527.
Topics: Buspirone; Dementia; Depression; Drug Therapy, Combination; Humans; Psychotic Disorders; Selective S | 1998 |
Serotonin syndrome. A common but often unrecognized psychiatric condition.
Topics: Aged; Anxiety Disorders; Buspirone; Citalopram; Depression; Female; Humans; Selective Serotonin Reup | 2001 |
Effects of genetic polymorphism of CYP1A2 inducibility on the steady-state plasma concentrations of trazodone and its active metabolite m-chlorophenylpiperazine in depressed Japanese patients.
Topics: Adult; Alleles; Antidepressive Agents, Second-Generation; Chromatography, High Pressure Liquid; Cyto | 2001 |
Myoclonus secondary to the concurrent use of trazodone and fluoxetine.
Topics: Adult; Antidepressive Agents, Second-Generation; Depression; Drug Synergism; Fluoxetine; HIV Infecti | 2001 |
A hemodialysis patient with trazodone-induced parkinsonism.
Topics: Antidepressive Agents, Second-Generation; Depression; Humans; Kidney Failure, Chronic; Male; Middle | 2002 |
[Trazodone: an Italian drug recently registered in the USSR].
Topics: Depression; Humans; Mental Disorders; Piperazines; Psychophysiologic Disorders; Trazodone | 1979 |
Trazodone in depressions.
Topics: Depression; Double-Blind Method; Humans; Imipramine; Piperazines; Trazodone | 1979 |
[Treatment of depression in the menopause with trazodone].
Topics: Adjustment Disorders; Anxiety; Depression; Female; Humans; Menopause; Middle Aged; Piperazines; Traz | 1979 |
[Variations in the urinary level of MHPG in depressive syndromes].
Topics: Adult; Age Factors; Aged; Antidepressive Agents, Tricyclic; Anxiety; Depression; Depressive Disorder | 1979 |
A study of serum levels of trazodone produced in man following single or repeated oral administrations.
Topics: Administration, Oral; Anxiety; Depression; Dose-Response Relationship, Drug; Female; Humans; Male; P | 1978 |
The influence of trazodone on the circulatory system in patients with endogenous depression. I. Basic circulatory parameters.
Topics: Adult; Blood Circulation; Blood Pressure; Depression; Female; Humans; Male; Middle Aged; Piperazines | 1976 |
The influence of trazodone on the circulatory system in patients with endogenous depression. II. Influence on vascular reflexes.
Topics: Adult; Blood Circulation; Cold Temperature; Depression; Humans; Middle Aged; Piperazines; Reflex; Re | 1976 |
[Treatment of depressive syndrome with trazodone (author's transl)].
Topics: Adult; Depression; Drug Evaluation; Female; Humans; Male; Middle Aged; Piperazines; Trazodone | 1975 |
Insights in the use of trazodone in depressed patients. Proceedings from the VIII World Congress of Psychiatry. Athens, Greece, October 12-19, 1989.
Topics: Depression; Humans; Trazodone | 1990 |
Trazodone treatment in clomipramine-resistant obsessive-compulsive disorder.
Topics: Adult; Analysis of Variance; Clinical Trials as Topic; Clomipramine; Depression; Drug Resistance; Fe | 1990 |
Adverse interactions encountered when using trazodone to treat insomnia associated with fluoxetine.
Topics: Adult; Depression; Drug Interactions; Female; Fluoxetine; Humans; Sleep Initiation and Maintenance D | 1990 |
Persistent dystonia associated with buspirone.
Topics: Anxiety; Buspirone; Depression; Drug Therapy, Combination; Dystonia; Female; Follow-Up Studies; Huma | 1990 |
Trazodone-induced palinopsia.
Topics: Adult; Afterimage; Depression; Female; Hallucinations; Humans; Male; Middle Aged; Trazodone; Vision | 1990 |
[A new sustained-release formulation of trazodone for treatment of minor psychopathological depression. A controlled study].
Topics: Aged; Delayed-Action Preparations; Depression; Female; Humans; Male; Middle Aged; Trazodone | 1989 |
Beyond the limits of typical antidepressants.
Topics: Amines; Antidepressive Agents, Tricyclic; Brain; Depression; Humans; Receptors, Adrenergic, alpha; S | 1988 |
Effects of trazodone treatment on serotonergic function in depressed patients.
Topics: Adult; Affect; Aged; Blood Pressure; Depression; Female; Growth Hormone; Humans; Male; Middle Aged; | 1988 |
Regression toward the mean?
Topics: Cerebrovascular Disorders; Depression; Female; Humans; Male; Statistics as Topic; Trazodone | 1987 |
Generalized pustular psoriasis precipitated by trazodone in the treatment of depression.
Topics: Adult; Depression; Humans; Male; Psoriasis; Trazodone | 1986 |
Mania following change from trazodone to imipramine.
Topics: Adult; Bipolar Disorder; Depression; Female; Humans; Imipramine; Middle Aged; Trazodone | 1985 |