Compounds > psycholeine

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psycholeine

Description

psycholeine: structure given in first source; isolated from the tropical plant Psychotria oleoides; exhibits somatostatin antagonistic activity on growth hormone secretion [MeSH]

Cross-References

ID Source	ID
PubMed CID	5748504
MeSH ID	M0207767

Synonyms (7)

Synonym
calycanthine, 8,8'-bis(2,3,8,8a-tetrahydro-1-methylpyrrolo(2,3-b)indo-3a(1h)-yl)-, (2alpha,3alpha,8(3ar,8ar),8'(3ar,8ar))-
144424-79-3
calycanthine, 8,8'-bis(2,3,8,8a-tetrahydro-1-methylpyrrolo(2,3-b)indol-3a(1h)-yl)-, (2alpha,3'alpha,8(3ar,8ar),8'(3ar,8ar))-
psycholeine
13,16-dimethyl-1,7-bis(1-methyl-2,3,8,8a-tetrahydropyrrolo[2,3-b]indol-3a(1h)-yl)-5,6,11,12-tetrahydro-5,10b:11,4b-di(epiminoethano)dibenzo[c,h][2,6]naphthyridine
DTXSID20932314
(2r,11s)-5,14-bis[(3ar,8br)-3-methyl-1,2,3a,4-tetrahydropyrrolo[2,3-b]indol-8b-yl]-19,24-dimethyl-3,12,21,24-tetrazahexacyclo[9.7.3.32,10.01,10.04,9.013,18]tetracosa-4,6,8,13,15,17-hexaene

Research

Studies (5)

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	0 (0.00)	18.7374
1990's	2 (40.00)	18.2507
2000's	1 (20.00)	29.6817
2010's	2 (40.00)	24.3611
2020's	0 (0.00)	2.80

Study Types

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	0 (0.00%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	5 (100.00%)	84.16%

Substance	Studies	Classes	Roles	First Year	Last Year	Average Age	Relationship Strength	Trials	pre-1990	1990's	2000's	2010's	post-2020
quadrigemine a	4	pyrroloindole		1992	2017	22.5	high	0	0	2	1	1	0
magnesium hydroxide	2			1992	2017	19.5	high	0	0	1	0	1	0

Condition	Indicated	Studies	First Year	Last Year	Average Age	Relationship Strength	Trials	pre-1990	1990's	2000's	2010's	post-2020
Burnout, Professional	0	1	2011	2011	13.0	high	0	0	0	0	1	0
Chronic Disease	0	1	2011	2011	13.0	high	0	0	0	0	1	0
Chronic Illness	0	1	2011	2011	13.0	high	0	0	0	0	1	0
Depression	0	1	2011	2011	13.0	high	0	0	0	0	1	0