Page last updated: 2024-11-06

prednisolone and Depression

prednisolone has been researched along with Depression in 25 studies

Prednisolone: A glucocorticoid with the general properties of the corticosteroids. It is the drug of choice for all conditions in which routine systemic corticosteroid therapy is indicated, except adrenal deficiency states.
prednisolone : A glucocorticoid that is prednisone in which the oxo group at position 11 has been reduced to the corresponding beta-hydroxy group. It is a drug metabolite of prednisone.

Depression: Depressive states usually of moderate intensity in contrast with MAJOR DEPRESSIVE DISORDER present in neurotic and psychotic disorders.

Research Excerpts

ExcerptRelevanceReference
"We report a case of anorexia nervosa in a 14-year-old girl following withdrawal of oral prednisolone used in the treatment of asthma."3.69Anorexia nervosa and steroid withdrawal. ( Lacey, JH; Morgan, J, 1996)
"Prednisolone has no effect on withdrawal headache in unselected patients with chronic daily headache and medication overuse."2.73Prednisolone does not reduce withdrawal headache: a randomized, double-blind study. ( Bøe, MG; Mygland, A; Salvesen, R, 2007)
"We assessed Demographic data, the Systemic Lupus Erythematosus Activity Index, the Systemic Lupus International Collaborating Clinics Damage Index, Numeric Rating Scale, Fatigue Severity Scale, Body Image Scale, and the ENRICHD Social Support Instrument."1.72Prevalence and biopsychosocial factors associated with depressive symptoms among patients living with systemic lupus erythematosus in clinical settings in urban Thailand. ( Narupan, N; Pumpuang, W; Seeherunwong, A, 2022)
" Headache had led to chronic use of analgesics and to drug-treated depression."1.35[Severe chronic headache with depression induced by pachymeningitis in Wegener's granulomatosis]. ( Fischer, V; Pelzer, C; von Bierbrauer, A, 2008)
"Four patients with systemic lupus erythematosus (SLE) are described in whom there were major psychiatric complications."1.26Psychiatric problems in systemic lupus erythematosus. ( Dick, WC; Grennan, DM; MacNeill, A; Ward, D, 1976)

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-199010 (40.00)18.7374
1990's1 (4.00)18.2507
2000's6 (24.00)29.6817
2010's5 (20.00)24.3611
2020's3 (12.00)2.80

Authors

AuthorsStudies
Aoki, S1
Deyama, S1
Sugie, R1
Ishimura, K1
Fukuda, H1
Shuto, S1
Minami, M1
Kaneda, K1
Narupan, N1
Seeherunwong, A1
Pumpuang, W1
Bahar-Ozdemir, Y1
Sencan, S1
Ercalik, T1
Kokar, S1
Gunduz, OH1
Lisitsyna, TA1
Vel'tishchev, DIu1
Gerasimov, AN1
Seravina, OF1
Kovalevskaia, OB1
Zel'tyn', AE1
Novikov, AA1
Aleksandrova, EN1
Tallerova, AV1
Kovalenko, LP1
Nagane, Y2
Akaishi, T1
Nakashima, I1
Misu, T1
Fujihara, K1
Aoki, M2
Murai, H1
Imai, T1
Yamamoto, D1
Tsuda, E1
Minami, N1
Suzuki, Y1
Kanai, T1
Uzawa, A1
Kawaguchi, N1
Masuda, M1
Konno, S1
Suzuki, H1
Utsugisawa, K1
Kajiyama, Y1
Iijima, Y1
Chiba, S1
Furuta, M1
Ninomiya, M1
Izumi, A1
Shibata, S1
Kunugi, H1
Yukioka, M1
Komatsubara, Y1
Maeda, A1
Shichikawa, K1
Yukioka, K1
Furumitsu, Y1
Fauchais, AL1
Boivin, V1
Hachulla, E1
Michon-Pasturel, U1
Lambert, M1
Queyrel, V1
Hebbar, M1
Hatron, PY1
Devulder, B1
RAILTON, IE1
WRIGHT, V1
WALKER, WC1
WOOD, EA1
MCDUFFIE, FC1
Lewis, JJ1
Iezzoni, JC1
Berg, CL1
Bøe, MG1
Mygland, A1
Salvesen, R1
von Bierbrauer, A1
Pelzer, C1
Fischer, V1
McKinney, WT1
Kane, FJ1
Hope-Simpson, RE1
Morgan, J1
Lacey, JH1
McNeil, C1
MacNeill, A1
Grennan, DM1
Ward, D1
Dick, WC1
Lasić, S1
Bobarević, N1
Nikolin, B1
Tselibeev, BA1
Brusilovskaia, MI1
Sharma, S1
Gajwani, AK1
Gabriel, R1
Joekes, AM1
Orton, E1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Medication Overuse Headache: A Randomised Double Blind Study of Prednisolone or Placebo in Withdrawal Therapy (Phase 3), and a Randomised 1 Year Follow up by Neurologist or General Physician After Successful Withdrawal Therapy[NCT00135122]Phase 3100 participants (Actual)Interventional2003-09-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for prednisolone and Depression

ArticleYear
[Clinical factors affecting quality of life and treatment targets in patients with myasthenia gravis].
    Rinsho shinkeigaku = Clinical neurology, 2013, Volume: 53, Issue:11

    Topics: Adult; Aged; Cohort Studies; Cross-Sectional Studies; Cushing Syndrome; Depression; Female; Follow-U

2013

Trials

1 trial available for prednisolone and Depression

ArticleYear
Prednisolone does not reduce withdrawal headache: a randomized, double-blind study.
    Neurology, 2007, Jul-03, Volume: 69, Issue:1

    Topics: Adolescent; Adult; Aged; Analgesics; Anxiety; Combined Modality Therapy; Depression; Double-Blind Me

2007

Other Studies

23 other studies available for prednisolone and Depression

ArticleYear
The antidepressant-like effect of resolvin E1 in repeated prednisolone-induced depression model mice.
    Behavioural brain research, 2022, 02-10, Volume: 418

    Topics: Animals; Antidepressive Agents; Depression; Disease Models, Animal; Dose-Response Relationship, Drug

2022
Prevalence and biopsychosocial factors associated with depressive symptoms among patients living with systemic lupus erythematosus in clinical settings in urban Thailand.
    BMC psychiatry, 2022, 02-09, Volume: 22, Issue:1

    Topics: Cross-Sectional Studies; Depression; Fatigue; Humans; Lupus Erythematosus, Systemic; Pain; Prednisol

2022
The Effect of Pre-Treatment Depression, Anxiety and Somatization Levels on Transforaminal Epidural Steroid Injection: A Prospective Observational Study.
    Pain physician, 2020, Volume: 23, Issue:3

    Topics: Adult; Aged; Anesthetics, Local; Anti-Inflammatory Agents; Anxiety; Bupivacaine; Depression; Female;

2020
[Perception of pain in rheumatoid arthritis: relation to inflammation, psychic disorders, functional status, and quality of life].
    Klinicheskaia meditsina, 2013, Volume: 91, Issue:3

    Topics: Arthritis, Rheumatoid; Depression; Female; Glucocorticoids; Health Status; Humans; Inflammation; Mal

2013
Depressive state and chronic fatigue in multiple sclerosis and neuromyelitis optica.
    Journal of neuroimmunology, 2015, Jun-15, Volume: 283

    Topics: Adult; Aged; Carnitine; Chronic Disease; Comorbidity; Depression; Fatigue; Female; Gait Disorders, N

2015
Social disadvantages associated with myasthenia gravis and its treatment: a multicentre cross-sectional study.
    BMJ open, 2017, 02-23, Volume: 7, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Cross-Sectional Studies; Depression; Female; Humans; Income; Japan;

2017
Prednisolone causes anxiety- and depression-like behaviors and altered expression of apoptotic genes in mice hippocampus.
    Progress in neuro-psychopharmacology & biological psychiatry, 2010, Feb-01, Volume: 34, Issue:1

    Topics: Acoustic Stimulation; Animals; Anxiety; Apoptosis; Depression; Disease Models, Animal; Dose-Response

2010
[Depressive tendency in patients with RA].
    Ryumachi. [Rheumatism], 2002, Volume: 42, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Depression; Female;

2002
[Psychiatric complications of corticoid therapy in the elderly over 65 years of age treated for Horton disease].
    La Revue de medecine interne, 2002, Volume: 23, Issue:10

    Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents; Anxiety Disorders; Bipolar Disorder; Cluster Head

2002
The use of corticoids in postpartum depression.
    Journal of the American Medical Women's Association, 1961, Volume: 16

    Topics: Adrenal Cortex Hormones; Depression; Depression, Postpartum; Depressive Disorder; Female; Humans; Po

1961
NIALAMIDE AS A "STEROID SPARING" AGENT IN THE TREATMENT OF RHEUMATOID ARTHRITIS.
    Annals of the rheumatic diseases, 1963, Volume: 22

    Topics: Arthritis; Arthritis, Rheumatoid; Depression; Humans; Methylprednisolone; Nialamide; Placebos; Predn

1963
BONE MARROW DEPRESSION AFTER DRUG THERAPY IN PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS.
    Annals of the rheumatic diseases, 1965, Volume: 24

    Topics: Adolescent; Agranulocytosis; Anemia; Anemia, Aplastic; Anti-Bacterial Agents; Bone Marrow; Bone Marr

1965
Methylphenidate-induced autoimmune hepatitis.
    Digestive diseases and sciences, 2007, Volume: 52, Issue:2

    Topics: Alanine Transaminase; Anti-Inflammatory Agents; Aspartate Aminotransferases; Bilirubin; Central Nerv

2007
[Severe chronic headache with depression induced by pachymeningitis in Wegener's granulomatosis].
    Deutsche medizinische Wochenschrift (1946), 2008, Volume: 133, Issue:5

    Topics: Adult; Analgesics; Anti-Inflammatory Agents; Antibodies, Antineutrophil Cytoplasmic; Antidepressive

2008
Pancytopenia due to chlorpromazine.
    The American journal of psychiatry, 1967, Volume: 123, Issue:7

    Topics: Anemia, Aplastic; Chlorpromazine; Depression; Hematocrit; Hemoglobinometry; Humans; Male; Middle Age

1967
Herpes zoster in the elderly.
    Geriatrics, 1967, Volume: 22, Issue:9

    Topics: Adolescent; Adult; Aged; Child; Depression; Facial Paralysis; Herpes Zoster; Humans; Middle Aged; Pa

1967
Anorexia nervosa and steroid withdrawal.
    The International journal of eating disorders, 1996, Volume: 19, Issue:2

    Topics: Adolescent; Anorexia Nervosa; Anti-Inflammatory Agents; Asthma; Bulimia; Depression; Female; Humans;

1996
Cancer fatigue: one drug fails but more are in the pipeline.
    Journal of the National Cancer Institute, 2001, Jun-20, Volume: 93, Issue:12

    Topics: Clinical Trials as Topic; Depression; Dexamethasone; Fatigue; Humans; Neoplasms; Paroxetine; Prednis

2001
Psychiatric problems in systemic lupus erythematosus.
    The British journal of psychiatry : the journal of mental science, 1976, Volume: 128

    Topics: Adult; Aggression; Confusion; Delusions; Depression; Female; Hallucinations; Humans; Hypertension; L

1976
Simultaneous determination of prednisone, prednisolone, cortisol and dexamethasone in plasma by high-performance liquid chromatography.
    Journal of pharmaceutical and biomedical analysis, 1989, Volume: 7, Issue:6

    Topics: Chromatography, High Pressure Liquid; Depression; Dexamethasone; Glucocorticoids; Humans; Hydrocorti

1989
[Psychological disturbances in influenza].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1968, Volume: 68, Issue:3

    Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Aged; Bipolar Disorder; Body Temperature; Catatonia;

1968
Prednisolone induced depression (a case report).
    The Journal of the Association of Physicians of India, 1973, Volume: 21, Issue:10

    Topics: Adult; Depression; Female; Humans; Prednisolone

1973
Hypervitaminosis D, anaemia and renal failure.
    Postgraduate medical journal, 1970, Volume: 46, Issue:537

    Topics: Anemia; Calcium; Depression; Female; Humans; Kidney Failure, Chronic; Middle Aged; Prednisolone; Vit

1970